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Gene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 2-butoxyethanol | decreases expression | EXP | | 6480464 | n-butoxyethanol results in decreased expression of IL16 mRNA | CTD | PMID:19812364 | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of IL16 mRNA | CTD | PMID:18648102 | benzene | increases expression | ISO | RGD:1351288 | 6480464 | Benzene results in increased expression of IL16 mRNA | CTD | PMID:15929907 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of IL16 mRNA | CTD | PMID:22228805 | bisphenol A | increases expression | ISO | RGD:1583872 | 6480464 | bisphenol A results in increased expression of IL16 mRNA | CTD | PMID:18180321 | cimetidine | multiple interactions | ISO | RGD:1351288 | 6480464 | Cimetidine inhibits the reaction [HRH2 protein promotes the reaction [Histamine results in increased expression of IL16 protein]] | CTD | PMID:12235264 | clobenpropit | multiple interactions | ISO | RGD:1351288 | 6480464 | HRH2 protein promotes the reaction [clobenpropit results in increased expression of IL16 protein] | CTD | PMID:12235264 | clobenpropit | increases expression | ISO | RGD:1351288 | 6480464 | clobenpropit results in increased expression of IL16 protein | CTD | PMID:12235264 | cyclophosphamide | decreases expression | EXP | | 6480464 | Cyclophosphamide results in decreased expression of IL16 mRNA | CTD | PMID:21041162 | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of IL16 mRNA | CTD | PMID:21041162 | diethylstilbestrol | decreases expression | EXP | | 6480464 | Diethylstilbestrol results in decreased expression of IL16 mRNA | CTD | PMID:21041162 | histamine | multiple interactions | ISO | RGD:1351288 | 6480464 | Cimetidine inhibits the reaction [HRH2 protein promotes the reaction [Histamine results in increased expression of IL16 protein]]; more ... | CTD | PMID:12235264 | histamine | increases expression | ISO | RGD:1351288 | 6480464 | Histamine results in increased expression of IL16 protein | CTD | PMID:12235264 | melphalan | decreases expression | ISO | RGD:1351288 | 6480464 | Melphalan results in decreased expression of IL16 mRNA | CTD | PMID:22363485 | methotrexate | decreases expression | ISO | RGD:1351288 | 6480464 | Methotrexate results in decreased expression of IL16 mRNA | CTD | PMID:17400583 | mono(2-ethylhexyl) phthalate | decreases expression | EXP | | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of IL16 mRNA | CTD | PMID:22401849 | mycophenolic acid | increases expression | EXP | | 6480464 | Mycophenolic Acid results in increased expression of IL16 mRNA | CTD | PMID:19818335 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of IL16 mRNA | CTD | PMID:17562736 | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide results in decreased expression of IL16 mRNA | CTD | PMID:19073995 | simvastatin | multiple interactions | EXP | | 6480464 | [Lipopolysaccharides co-treated with Simvastatin] results in increased expression of IL16 mRNA | CTD | PMID:15665042 | sterigmatocystin | increases expression | EXP | | 6480464 | Sterigmatocystin results in increased expression of IL16 mRNA | CTD | PMID:19818335 | titanium dioxide | affects expression | ISO | RGD:1351288 | 6480464 | titanium dioxide affects the expression of IL16 mRNA | CTD | PMID:19695317 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Phenotype Annotations
Disease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Phenotype Annotations
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References - curated
References - uncurated
RGD Disease Portals| Il16 has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Il16 (Mus musculus) |
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| IL16 (Homo sapiens) |
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| Il16 (Rattus norvegicus) |
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Position Markers| D7Mit261 |
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| AF017111 |
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QTLs in Region (Mouse Genome Assembly Build 37)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| RefSeq Acc Id: | NM_010551 | |||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | |||||||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||||||||
| Protein Acc Id: | NP_034681 | |||||||||||||||||||||||||
| Position: |
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Protein Sequences
Promoters| RGD ID: | 6841328 | ||||||||||
| Promoter ID: | MM_KWN:51391 | ||||||||||
| Type: | Non-CpG | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | Brain, Lung, Spleen | ||||||||||
| Transcripts: | OTTMUST00000067592, UC009IDT.1 | ||||||||||
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| RGD ID: | 6849224 | ||||||||||
| Promoter ID: | MM_XEF:6644 | ||||||||||
| Type: | Non-CpG | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | Brain, Lung | ||||||||||
| Transcripts: | NM_204352 | ||||||||||
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| RGD ID: | 6849223 | ||||||||||
| Promoter ID: | MM_XEF:6645 | ||||||||||
| Type: | Non-CpG | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | Brain | ||||||||||
| Transcripts: | NM_172217 | ||||||||||
| Position: |
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| RGD ID: | 6841327 | ||||||||||
| Promoter ID: | MM_KWN:51393 | ||||||||||
| Type: | Non-CpG | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | Brain | ||||||||||
| Transcripts: | OTTMUST00000067595 | ||||||||||
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| RGD ID: | 6841326 | ||||||||||
| Promoter ID: | MM_KWN:51394 | ||||||||||
| Type: | Non-CpG | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | Brain | ||||||||||
| Transcripts: | ENSMUST00000001792 | ||||||||||
| Position: |
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| RGD ID: | 6841564 | ||||||||||
| Promoter ID: | MM_KWN:51396 | ||||||||||
| Type: | Non-CpG | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | Lung | ||||||||||
| Transcripts: | UC009IDU.1 | ||||||||||
| Position: |
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSMUSG00000001741 | ENTREZGENE |
| Ensembl Protein | ENSMUSP00000001792 | ENTREZGENE |
| Ensembl Transcript | ENSMUST00000001792 | ENTREZGENE |
| Entrez Gene | 16170 | ENTREZGENE |
| Germonline | ENSMUSG00000001741 | |
| HomoloGene Group ID | 18157 | ENTREZGENE |
| InterPro | Interleukin-16 | UniProtKB/Swiss-Prot |
| PDZ/DHR/GLGF | UniProtKB/Swiss-Prot | |
| IPI | IPI00137805 | UniProtKB/Swiss-Prot |
| IPI00880512 | UniProtKB/TrEMBL | |
| IPI00880626 | UniProtKB/TrEMBL | |
| IPI00930865 | UniProtKB/Swiss-Prot | |
| KEGG Report | mmu:16170 | ENTREZGENE, UniProtKB/Swiss-Prot |
| MGD | MGI:1270855 | ENTREZGENE |
| Pfam | PDZ | UniProtKB/Swiss-Prot |
| PRINTS | INTRLEUKIN16 | UniProtKB/Swiss-Prot |
| PROSITE | PDZ | UniProtKB/Swiss-Prot |
| SMART | PDZ | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | PDZ | UniProtKB/Swiss-Prot |
| UniGene | Mm.10137 | ENTREZGENE |
| UniProt | D3Z3C7_MOUSE | UniProtKB/TrEMBL |
| D6RI15_MOUSE | UniProtKB/TrEMBL | |
| IL16_MOUSE | UniProtKB/Swiss-Prot | |
| Q3UZ81_MOUSE | UniProtKB/TrEMBL |
| More on Il16 | |
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Entrez Gene |
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Ensembl Gene |
![]() | Genome Browser |
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MGI Report |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 1557964 |
| Created: | 2005-11-30 |
| Species: | Mus musculus |
| Last Modified: | 2013-02-27 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




