| (+)-pilocarpine | increases expression | ISO | RGD:619823 | 6480464 | Pilocarpine results in increased expression of XRCC1 mRNA | CTD | PMID:17971868 |
| 1-methylphenanthrene | multiple interactions | ISO | RGD:732968 | 6480464 | [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of XRCC1 mRNA | CTD | PMID:17690111 |
| 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of XRCC1 mRNA | CTD | PMID:17555576 |
| 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | RGD:732968 | 6480464 | [2,2,4,4-tetrabromodiphenyl ether co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of XRCC1 mRNA | CTD | PMID:18948301 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:732968 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of XRCC1 mRNA | CTD | PMID:16039398 PMID:18762178 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of XRCC1 mRNA | CTD | PMID:21570461 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:619823 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of XRCC1 mRNA | CTD | PMID:21215274 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:732968 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of XRCC1 mRNA | CTD | PMID:18762178 PMID:16039398 |
| 4-hydroxyphenyl retinamide | multiple interactions | ISO | RGD:732968 | 6480464 | Ascorbic Acid inhibits the reaction [Fenretinide results in decreased expression of XRCC1 protein]; more ... | CTD | PMID:16124896 |
| 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:732968 | 6480464 | Fenretinide results in decreased expression of XRCC1 protein | CTD | PMID:16124896 |
| 5-aza-2'-deoxycytidine | multiple interactions | ISO | RGD:732968 | 6480464 | decitabine inhibits the reaction [Cadmium Chloride results in decreased expression of XRCC1 protein]; more ... | CTD | PMID:22112500 |
| 5-fluoro-2'-deoxyuridine | decreases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 protein results in decreased susceptibility to Floxuridine | CTD | PMID:21613406 PMID:22194930 |
| 5-fluoro-2'-deoxyuridine | decreases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 protein results in decreased susceptibility to Floxuridine | CTD | PMID:22194930 PMID:21613406 |
| 6-propyl-2-thiouracil | increases expression | ISO | RGD:619823 | 6480464 | Propylthiouracil results in increased expression of XRCC1 mRNA | CTD | PMID:18077114 |
| all-trans-retinoic acid | decreases expression | EXP | | 6480464 | Tretinoin results in decreased expression of XRCC1 mRNA | CTD | PMID:16604517 |
| ammonium chloride | affects expression | ISO | RGD:619823 | 6480464 | Ammonium Chloride affects the expression of XRCC1 mRNA | CTD | PMID:16483693 |
| arsenic atom | increases expression | ISO | RGD:732968 | 6480464 | Arsenic results in increased expression of XRCC1 mRNA | CTD | PMID:12773770 |
| arsenic atom | affects response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism affects the susceptibility to Arsenic | CTD | PMID:17374727 |
| arsenic atom | multiple interactions | ISO | RGD:732968 | 6480464 | Curcumin inhibits the reaction [Arsenic results in decreased expression of XRCC1 mRNA]; more ... | CTD | PMID:21332098 |
| arsenic atom | decreases expression | ISO | RGD:732968 | 6480464 | Arsenic results in decreased expression of XRCC1 protein; more ... | CTD | PMID:21332098 |
| asbestos | increases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism results in increased susceptibility to Asbestos | CTD | PMID:16564556 |
| asbestos | affects response to substance | ISO | RGD:732968 | 6480464 | XRCC1 protein affects the susceptibility to Asbestos | CTD | PMID:16944782 |
| benzene | affects response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism affects the susceptibility to Benzene | CTD | PMID:18214807 PMID:17095285 |
| benzene | affects response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism affects the susceptibility to Benzene | CTD | PMID:17095285 PMID:18214807 |
| benzene | affects response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene SNP affects the susceptibility to Benzene | CTD | PMID:15612468 |
| benzene | decreases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene SNP results in decreased susceptibility to Benzene | CTD | PMID:16284386 |
| benzene | increases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene SNP results in increased susceptibility to Benzene | CTD | PMID:16284386 |
| benzo[a]pyrene | multiple interactions | ISO | RGD:732968 | 6480464 | [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of XRCC1 mRNA; more ... | CTD | PMID:17690111 |
| bleomycin A2 | decreases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 results in decreased susceptibility to Bleomycin | CTD | PMID:20705543 |
| bleomycin A2 | affects response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism affects the susceptibility to Bleomycin | CTD | PMID:12082022 |
| cadmium dichloride | multiple interactions | ISO | RGD:732968 | 6480464 | decitabine inhibits the reaction [Cadmium Chloride results in decreased expression of XRCC1 mRNA]; more ... | CTD | PMID:22112500 |
| cadmium dichloride | increases methylation | ISO | RGD:732968 | 6480464 | Cadmium Chloride results in increased methylation of XRCC1 promoter | CTD | PMID:22112500 |
| cadmium dichloride | decreases expression | ISO | RGD:732968 | 6480464 | Cadmium Chloride results in decreased expression of XRCC1 mRNA; more ... | CTD | PMID:22112500 |
| chloroethene | multiple interactions | ISO | RGD:732968 | 6480464 | GSTM1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]; more ... | CTD | PMID:16097394 |
| chloroethene | increases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene SNP results in increased susceptibility to Vinyl Chloride | CTD | PMID:17555083 more ... |
| chloroethene | increases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene SNP results in increased susceptibility to Vinyl Chloride | CTD | PMID:18420361 more ... |
| chloroethene | increases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene SNP results in increased susceptibility to Vinyl Chloride | CTD | PMID:20100738 more ... |
| chloroethene | increases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene SNP results in increased susceptibility to Vinyl Chloride | CTD | PMID:17555083 more ... |
| chloroethene | multiple interactions | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene] | CTD | PMID:12010862 PMID:16881598 |
| chloroethene | decreases expression | ISO | RGD:619823 | 6480464 | Vinyl Chloride results in decreased expression of XRCC1 protein | CTD | PMID:15256147 |
| chloroethene | increases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene SNP results in increased susceptibility to Vinyl Chloride | CTD | PMID:20100738 more ... |
| chloroethene | multiple interactions | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene] | CTD | PMID:16881598 PMID:12010862 |
| chloroethene | multiple interactions | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene] | CTD | PMID:16881598 |
| chloroethene | multiple interactions | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene] | CTD | PMID:14602524 |
| cisplatin | decreases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 mRNA results in decreased susceptibility to Cisplatin | CTD | PMID:15882455 |
| cisplatin | decreases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 protein results in decreased susceptibility to Cisplatin | CTD | PMID:19853026 |
| clofibrate | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of XRCC1 mRNA; more ... | CTD | PMID:17585979 |
| copper(2+) sulfate | decreases expression | ISO | RGD:732968 | 6480464 | Copper Sulfate results in decreased expression of XRCC1 mRNA | CTD | PMID:19549813 |
| crocidolite asbestos | decreases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 results in decreased susceptibility to Asbestos, Crocidolite | CTD | PMID:20705543 |
| curcumin | multiple interactions | ISO | RGD:732968 | 6480464 | Curcumin inhibits the reaction [Arsenic results in decreased expression of XRCC1 mRNA]; more ... | CTD | PMID:21332098 |
| cyclophosphamide | decreases expression | ISO | RGD:619823 | 6480464 | Cyclophosphamide results in decreased expression of XRCC1 mRNA | CTD | PMID:11056294 |
| cytarabine | increases expression | ISO | RGD:732968 | 6480464 | Cytarabine results in increased expression of XRCC1 mRNA | CTD | PMID:19194470 |
| Delta(9)-tetrahydrocannabinol | decreases expression | ISO | RGD:732968 | 6480464 | Tetrahydrocannabinol results in decreased expression of XRCC1 mRNA | CTD | PMID:16039398 |
| ethanol | increases expression | ISO | RGD:732968 | 6480464 | Ethanol results in increased expression of XRCC1 mRNA; more ... | CTD | PMID:22056336 |
| fluoranthene | multiple interactions | ISO | RGD:732968 | 6480464 | [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of XRCC1 mRNA | CTD | PMID:17690111 |
| formaldehyde | affects response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism affects the susceptibility to Formaldehyde | CTD | PMID:17290738 |
| furan | increases expression | EXP | | 6480464 | furan results in increased expression of XRCC1 mRNA | CTD | PMID:20194422 |
| gefitinib | affects response to substance | ISO | RGD:732968 | 6480464 | XRCC1 protein polymorphism affects the susceptibility to gefitinib | CTD | PMID:21264830 |
| genistein | decreases expression | EXP | | 6480464 | Genistein results in decreased expression of XRCC1 mRNA | CTD | PMID:16169203 |
| hydrogen peroxide | decreases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 results in decreased susceptibility to Hydrogen Peroxide | CTD | PMID:20705543 |
| L-ascorbic acid | multiple interactions | ISO | RGD:732968 | 6480464 | Ascorbic Acid inhibits the reaction [Fenretinide results in decreased expression of XRCC1 protein]; more ... | CTD | PMID:16124896 |
| lead(0) | decreases expression | ISO | RGD:732968 | 6480464 | Lead results in decreased expression of XRCC1 mRNA | CTD | PMID:19921347 |
| N-acetyl-L-cysteine | multiple interactions | ISO | RGD:732968 | 6480464 | Acetylcysteine inhibits the reaction [2,2,4,4-tetrabromodiphenyl ether results in decreased expression of XRCC1 mRNA] | CTD | PMID:18948301 |
| N-ethyl-N-nitrosourea | decreases expression | ISO | RGD:732968 | 6480464 | Ethylnitrosourea results in decreased expression of XRCC1 mRNA | CTD | PMID:21071726 |
| paracetamol | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of XRCC1 mRNA; more ... | CTD | PMID:17585979 |
| piperonyl butoxide | decreases expression | EXP | | 6480464 | Piperonyl Butoxide results in decreased expression of XRCC1 mRNA | CTD | PMID:17014948 |
| platinum | affects response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism affects the susceptibility to Platinum | CTD | PMID:18851872 |
| platinum(0) | affects response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism affects the susceptibility to Platinum | CTD | PMID:18851872 |
| resveratrol | increases expression | ISO | RGD:732968 | 6480464 | resveratrol results in increased expression of XRCC1 mRNA; more ... | CTD | PMID:22056336 |
| styrene | increases response to substance | ISO | RGD:732968 | 6480464 | XRCC1 gene polymorphism results in increased susceptibility to Styrene | CTD | PMID:15992842 |
| styrene | increases expression | ISO | RGD:732968 | 6480464 | Styrene results in increased expression of XRCC1 mRNA | CTD | PMID:21030303 |
| styrene | affects response to substance | ISO | RGD:732968 | 6480464 | XRCC1 protein polymorphism affects the susceptibility to Styrene | CTD | PMID:15468052 |
| styrene oxide | affects response to substance | ISO | RGD:732968 | 6480464 | XRCC1 protein polymorphism affects the susceptibility to styrene oxide | CTD | PMID:15468052 |
| tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of XRCC1 mRNA | CTD | PMID:17555576 |
| trans-resveratrol | increases expression | ISO | RGD:732968 | 6480464 | resveratrol results in increased expression of XRCC1 mRNA; more ... | CTD | PMID:22056336 |
| troglitazone | decreases expression | ISO | RGD:732968 | 6480464 | troglitazone results in decreased expression of XRCC1 mRNA | CTD | PMID:19631733 |