| (-)-epigallocatechin 3-gallate | decreases expression | ISO | RGD:1352097 | 6480464 | epigallocatechin gallate results in decreased expression of POMC mRNA | CTD | PMID:20706672 |
| (S)-colchicine | increases secretion | ISO | RGD:3366 | 6480464 | Colchicine results in increased secretion of POMC protein | CTD | PMID:2453250 |
| (S)-nicotine | multiple interactions | EXP | | 6480464 | POMC protein affects the reaction [Nicotine results in increased abundance of Dopamine] | CTD | PMID:15689546 |
| (S)-nicotine | affects expression | ISO | RGD:3366 | 6480464 | Nicotine affects the expression of POMC protein | CTD | PMID:22975262 |
| (S)-nicotine | affects response to substance | EXP | | 6480464 | POMC protein affects the susceptibility to Nicotine | CTD | PMID:19376143 |
| (Z)-hex-3-en-1-ol | multiple interactions | ISO | RGD:3366 | 6480464 | [2,5-dihydro-2,4,5-trimethylthiazoline co-treated with 3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC protein; more ... | CTD | PMID:21515296 |
| (Z)-hex-3-en-1-ol | multiple interactions | ISO | RGD:3366 | 6480464 | [3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC | CTD | PMID:19103229 |
| 11-deoxycorticosterone | increases abundance | ISO | RGD:1352097 | 6480464 | POMC protein results in increased abundance of Desoxycorticosterone | CTD | PMID:3015796 |
| 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of POMC mRNA | CTD | PMID:17942748 |
| 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POMC mRNA | CTD | PMID:17942748 |
| 17beta-estradiol | multiple interactions | ISO | RGD:3366 | 6480464 | Estradiol affects the reaction [Tetrahydrocannabinol results in increased expression of POMC mRNA] | CTD | PMID:11528220 |
| 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-hexadecafluorononanoic acid | increases secretion | EXP | | 6480464 | hexadecafluoro-nonanoic acid results in increased secretion of POMC protein alternative form | CTD | PMID:18583369 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of POMC mRNA; more ... | CTD | PMID:12520768 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:3366 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of POMC mRNA | CTD | PMID:15093705 PMID:18824019 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:3366 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of POMC mRNA | CTD | PMID:18824019 PMID:15093705 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:3366 | 6480464 | [Tetrachlorodibenzodioxin co-treated with LEP protein] affects the expression of POMC mRNA | CTD | PMID:15977195 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POMC mRNA | CTD | PMID:17942748 |
| 2,4-dinitrotoluene | affects expression | ISO | RGD:3366 | 6480464 | 2,4-dinitrotoluene affects the expression of POMC mRNA | CTD | PMID:21346803 |
| 2-hexenal | multiple interactions | ISO | RGD:3366 | 6480464 | [3-hexen-1-ol co-treated with 2-hexenal] inhibits the reaction [2,5-dihydro-2,4,5-trimethylthiazoline results in decreased expression of POMC protein]; more ... | CTD | PMID:21515296 |
| 2-hexenal | multiple interactions | ISO | RGD:3366 | 6480464 | [3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC | CTD | PMID:19103229 |
| 20-HETE | multiple interactions | ISO | RGD:3366 | 6480464 | N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine inhibits the reaction [POMC protein affects the abundance of 20-hydroxy-5,8,11,14-eicosatetraenoic acid] | CTD | PMID:19458537 |
| 20-HETE | increases abundance | ISO | RGD:3366 | 6480464 | POMC protein results in increased abundance of 20-hydroxy-5,8,11,14-eicosatetraenoic acid | CTD | PMID:19458537 PMID:18067589 |
| 20-HETE | increases abundance | ISO | RGD:3366 | 6480464 | POMC protein results in increased abundance of 20-hydroxy-5,8,11,14-eicosatetraenoic acid | CTD | PMID:18067589 PMID:19458537 |
| 3',5'-cyclic AMP | multiple interactions | ISO | RGD:3366 | 6480464 | [Theophylline co-treated with POMC protein] results in increased abundance of Cyclic AMP; more ... | CTD | PMID:4306506 |
| 3',5'-cyclic GMP | affects abundance | ISO | RGD:3366 | 6480464 | POMC protein affects the abundance of Cyclic GMP | CTD | PMID:11193135 |
| 3,4-methylenedioxymethamphetamine | decreases expression | EXP | | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of POMC mRNA | CTD | PMID:19523041 |
| 3,4-methylenedioxymethamphetamine | multiple interactions | EXP | | 6480464 | naltrindole inhibits the reaction [N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of POMC mRNA] | CTD | PMID:19523041 |
| 7,12-dimethyltetraphene | multiple interactions | ISO | RGD:3366 | 6480464 | POMC protein promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene] | CTD | PMID:7588239 |
| acetaldehyde | increases expression | ISO | RGD:3366 | 6480464 | Acetaldehyde results in increased expression of POMC protein; more ... | CTD | PMID:7704432 |
| acetylcholine | increases expression | ISO | RGD:3366 | 6480464 | Acetylcholine results in increased expression of POMC protein; more ... | CTD | PMID:7588217 |
| acetylcholine | multiple interactions | ISO | RGD:3366 | 6480464 | Atropine inhibits the reaction [Acetylcholine results in increased expression of POMC protein]; more ... | CTD | PMID:7588217 |
| acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of POMC mRNA; more ... | CTD | PMID:15003292 |
| aldosterone | multiple interactions | ISO | RGD:1352097 | 6480464 | Dexamethasone inhibits the reaction [POMC protein results in increased abundance of Aldosterone] | CTD | PMID:3015796 |
| aldosterone | increases secretion | ISO | RGD:3366 | 6480464 | POMC results in increased secretion of Aldosterone | CTD | PMID:1659878 |
| aldosterone | increases abundance | ISO | RGD:1352097 | 6480464 | POMC protein results in increased abundance of Aldosterone | CTD | PMID:3015796 |
| aldosterone | decreases abundance | ISO | RGD:1352097 | 6480464 | POMC protein results in decreased abundance of Aldosterone | CTD | PMID:2551692 |
| all-trans-retinol | increases expression | ISO | RGD:3366 | 6480464 | Vitamin A results in increased expression of POMC protein | CTD | PMID:17373634 |
| ammonium chloride | affects expression | ISO | RGD:3366 | 6480464 | Ammonium Chloride affects the expression of POMC mRNA | CTD | PMID:16483693 |
| apocynin | multiple interactions | ISO | RGD:3366 | 6480464 | acetovanillone inhibits the reaction [POMC protein affects the abundance of F2-Isoprostanes] | CTD | PMID:16053986 |
| aspartame | increases expression | ISO | RGD:1352097 | 6480464 | Aspartame results in increased expression of POMC protein alternative form | CTD | PMID:1805284 |
| atrazine | increases secretion | ISO | RGD:3366 | 6480464 | Atrazine results in increased secretion of POMC protein modified form | CTD | PMID:19690231 PMID:19710361 |
| atrazine | increases secretion | ISO | RGD:3366 | 6480464 | Atrazine results in increased secretion of POMC protein modified form | CTD | PMID:19710361 PMID:19690231 |
| atropine | multiple interactions | ISO | RGD:3366 | 6480464 | Atropine inhibits the reaction [Acetylcholine results in increased expression of POMC protein] | CTD | PMID:7588217 |
| benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in increased expression of POMC mRNA | CTD | PMID:21715664 |
| benzo[a]pyrene | increases expression | ISO | RGD:3366 | 6480464 | Benzo(a)pyrene results in increased expression of POMC mRNA | CTD | PMID:21839799 |
| beta-hexachlorocyclohexane | multiple interactions | EXP | | 6480464 | [Dichlorodiphenyl Dichloroethylene co-treated with beta-hexachlorocyclohexane] results in decreased expression of POMC mRNA | CTD | PMID:16758953 |
| bezafibrate | decreases expression | EXP | | 6480464 | Bezafibrate results in decreased expression of POMC mRNA | CTD | PMID:18787029 |
| bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:1352097 | 6480464 | Mustard Gas results in increased expression of POMC protein alternative form | CTD | PMID:8299707 |
| bromocriptine | decreases expression | ISO | RGD:3366 | 6480464 | Bromocriptine results in decreased expression of POMC protein alternative form | CTD | PMID:6274577 |
| bromocriptine | increases expression | ISO | RGD:1352097 | 6480464 | Bromocriptine results in increased expression of POMC protein modified form; more ... | CTD | PMID:1325994 |
| bromocriptine | multiple interactions | ISO | RGD:3366 | 6480464 | Bromocriptine inhibits the reaction [POMC protein results in decreased secretion of Corticosterone] | CTD | PMID:12742521 |
| bucladesine | increases expression | ISO | RGD:1352097 | 6480464 | Bucladesine results in increased expression of POMC mRNA; more ... | CTD | PMID:1325994 |
| buspirone | increases expression | ISO | RGD:1352097 | 6480464 | Buspirone results in increased expression of POMC protein | CTD | PMID:19762159 |
| buspirone | multiple interactions | ISO | RGD:1352097 | 6480464 | Imipramine inhibits the reaction [Buspirone results in increased expression of POMC protein] | CTD | PMID:19762159 |
| caffeine | increases secretion | ISO | RGD:3366 | 6480464 | Caffeine results in increased secretion of POMC protein alternative form | CTD | PMID:22959462 |
| capsaicin | multiple interactions | ISO | RGD:3366 | 6480464 | Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein]; more ... | CTD | PMID:2846107 |
| capsaicin | increases expression | ISO | RGD:3366 | 6480464 | Capsaicin results in increased expression of POMC protein | CTD | PMID:22150557 |
| capsaicin | multiple interactions | ISO | RGD:3366 | 6480464 | capsazepine inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; more ... | CTD | PMID:8925284 |
| capsaicin | increases secretion | ISO | RGD:3366 | 6480464 | Capsaicin results in increased secretion of POMC protein | CTD | PMID:8925284 |
| capsaicin | multiple interactions | ISO | RGD:3366 | 6480464 | Naproxen inhibits the reaction [Capsaicin results in increased expression of POMC protein]; more ... | CTD | PMID:22150557 |
| celecoxib | multiple interactions | ISO | RGD:3366 | 6480464 | celecoxib inhibits the reaction [docetaxel results in increased expression of POMC mRNA] | CTD | PMID:22902858 |
| chloroquine | multiple interactions | ISO | RGD:3366 | 6480464 | Chloroquine inhibits the reaction [POMC protein modified form results in increased chemical synthesis of Adrenal Cortex Hormones] | CTD | PMID:2993719 |
| citalopram | increases expression | ISO | RGD:1352097 | 6480464 | Citalopram results in increased expression of POMC protein | CTD | PMID:20414043 |
| clofibrate | increases expression | EXP | | 6480464 | Clofibrate results in increased expression of POMC mRNA | CTD | PMID:17585979 |
| clonidine | increases expression | ISO | RGD:1352097 | 6480464 | Clonidine results in increased expression of POMC protein | CTD | PMID:2455169 PMID:6089027 |
| clonidine | multiple interactions | ISO | RGD:3366 | 6480464 | Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein] | CTD | PMID:2846107 |
| clonidine | increases expression | ISO | RGD:1352097 | 6480464 | Clonidine results in increased expression of POMC protein | CTD | PMID:6089027 PMID:2455169 |
| clonidine | multiple interactions | ISO | RGD:3366 | 6480464 | Indomethacin inhibits the reaction [Clonidine results in increased secretion of POMC protein alternative form] | CTD | PMID:10898105 |
| clonidine | increases secretion | ISO | RGD:3366 | 6480464 | Clonidine results in increased secretion of POMC protein alternative form | CTD | PMID:10898105 |
| clonidine | decreases expression | ISO | RGD:3366 | 6480464 | Clonidine results in decreased expression of POMC protein | CTD | PMID:3039113 |
| clonidine | multiple interactions | ISO | RGD:1352097 | 6480464 | [Clonidine results in increased expression of POMC protein] which results in increased susceptibility to Naloxone | CTD | PMID:6089027 |
| clonidine (amino form) | increases expression | ISO | RGD:1352097 | 6480464 | Clonidine results in increased expression of POMC protein | CTD | PMID:2455169 PMID:6089027 |
| clonidine (amino form) | multiple interactions | ISO | RGD:3366 | 6480464 | Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein] | CTD | PMID:2846107 |
| clonidine (amino form) | increases expression | ISO | RGD:1352097 | 6480464 | Clonidine results in increased expression of POMC protein | CTD | PMID:6089027 PMID:2455169 |
| clonidine (amino form) | multiple interactions | ISO | RGD:3366 | 6480464 | Indomethacin inhibits the reaction [Clonidine results in increased secretion of POMC protein alternative form] | CTD | PMID:10898105 |
| clonidine (amino form) | increases secretion | ISO | RGD:3366 | 6480464 | Clonidine results in increased secretion of POMC protein alternative form | CTD | PMID:10898105 |
| clonidine (amino form) | decreases expression | ISO | RGD:3366 | 6480464 | Clonidine results in decreased expression of POMC protein | CTD | PMID:3039113 |
| clonidine (amino form) | multiple interactions | ISO | RGD:1352097 | 6480464 | [Clonidine results in increased expression of POMC protein] which results in increased susceptibility to Naloxone | CTD | PMID:6089027 |
| clonidine (imino form) | increases expression | ISO | RGD:1352097 | 6480464 | Clonidine results in increased expression of POMC protein | CTD | PMID:2455169 PMID:6089027 |
| clonidine (imino form) | multiple interactions | ISO | RGD:3366 | 6480464 | Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein] | CTD | PMID:2846107 |
| clonidine (imino form) | increases expression | ISO | RGD:1352097 | 6480464 | Clonidine results in increased expression of POMC protein | CTD | PMID:6089027 PMID:2455169 |
| clonidine (imino form) | multiple interactions | ISO | RGD:3366 | 6480464 | Indomethacin inhibits the reaction [Clonidine results in increased secretion of POMC protein alternative form] | CTD | PMID:10898105 |
| clonidine (imino form) | increases secretion | ISO | RGD:3366 | 6480464 | Clonidine results in increased secretion of POMC protein alternative form | CTD | PMID:10898105 |
| clonidine (imino form) | decreases expression | ISO | RGD:3366 | 6480464 | Clonidine results in decreased expression of POMC protein | CTD | PMID:3039113 |
| clonidine (imino form) | multiple interactions | ISO | RGD:1352097 | 6480464 | [Clonidine results in increased expression of POMC protein] which results in increased susceptibility to Naloxone | CTD | PMID:6089027 |
| cocaine | increases expression | ISO | RGD:3366 | 6480464 | Cocaine results in increased expression of POMC protein | CTD | PMID:9610951 PMID:17001283 |
| cocaine | increases expression | ISO | RGD:3366 | 6480464 | Cocaine results in increased expression of POMC protein | CTD | PMID:17001283 PMID:9610951 |
| cocaine | increases expression | ISO | RGD:3366 | 6480464 | Cocaine results in increased expression of POMC protein alternative form | CTD | PMID:8301594 |
| cocaine | multiple interactions | ISO | RGD:3366 | 6480464 | eticlopride inhibits the reaction [Cocaine results in increased expression of POMC protein] | CTD | PMID:17001283 |
| cocaine | increases response to substance | ISO | RGD:3366 | 6480464 | POMC results in increased susceptibility to Cocaine | CTD | PMID:19279569 |
| cocaine | multiple interactions | ISO | RGD:3366 | 6480464 | [CTAP octapeptide binds to and results in decreased activity of OPRM1 protein] inhibits the reaction [POMC protein results in increased susceptibility to Cocaine] | CTD | PMID:19279569 |
| cocaine | increases response to substance | EXP | | 6480464 | POMC results in increased susceptibility to Cocaine | CTD | PMID:18176854 |
| cocaine | increases secretion | ISO | RGD:1352097 | 6480464 | Cocaine results in increased secretion of POMC protein | CTD | PMID:11750770 |
| corticosterone | multiple interactions | ISO | RGD:3366 | 6480464 | Bromocriptine inhibits the reaction [POMC protein results in decreased secretion of Corticosterone] | CTD | PMID:12742521 |
| corticosterone | increases abundance | ISO | RGD:3366 | 6480464 | POMC protein results in increased abundance of Corticosterone | CTD | PMID:10518784 PMID:7588239 |
| corticosterone | increases abundance | ISO | RGD:3366 | 6480464 | POMC protein results in increased abundance of Corticosterone | CTD | PMID:10518784 |
| corticosterone | multiple interactions | ISO | RGD:3366 | 6480464 | oxophenylarsine inhibits the reaction [POMC protein results in increased abundance of Corticosterone]; more ... | CTD | PMID:10518784 |
| corticosterone | increases secretion | ISO | RGD:3366 | 6480464 | POMC results in increased secretion of Corticosterone | CTD | PMID:1659878 |
| corticosterone | decreases secretion | ISO | RGD:3366 | 6480464 | POMC protein results in decreased secretion of Corticosterone | CTD | PMID:12742521 |
| corticosterone | increases secretion | ISO | RGD:3366 | 6480464 | POMC protein results in increased secretion of Corticosterone | CTD | PMID:11132610 |
| corticosterone | decreases abundance | ISO | RGD:3366 | 6480464 | POMC protein results in decreased abundance of Corticosterone | CTD | PMID:11518849 |
| corticosterone | increases secretion | ISO | RGD:3366 | 6480464 | POMC protein modified form results in increased secretion of Corticosterone | CTD | PMID:20837582 |
| corticosterone | multiple interactions | ISO | RGD:3366 | 6480464 | Cromolyn Sodium inhibits the reaction [POMC results in increased secretion of Corticosterone] | CTD | PMID:1659878 |
| corticosterone | multiple interactions | ISO | RGD:3366 | 6480464 | fulvestrant inhibits the reaction [nonylphenol promotes the reaction [POMC protein modified form results in increased secretion of Corticosterone]]; more ... | CTD | PMID:20837582 |
| corticosterone | decreases secretion | ISO | RGD:3366 | 6480464 | Corticosterone results in decreased secretion of POMC protein | CTD | PMID:3015567 |
| corticosterone | multiple interactions | ISO | RGD:3366 | 6480464 | Corticosterone inhibits the reaction [Nitroprusside results in increased secretion of POMC protein] | CTD | PMID:3015567 |
| cortisol | increases abundance | ISO | RGD:1352097 | 6480464 | POMC protein results in increased abundance of Hydrocortisone | CTD | PMID:9881897 |
| cortisol | increases secretion | ISO | RGD:1352097 | 6480464 | POMC protein results in increased secretion of Hydrocortisone | CTD | PMID:11082157 PMID:1321309 |
| cortisol | increases secretion | ISO | RGD:1352097 | 6480464 | POMC protein results in increased secretion of Hydrocortisone | CTD | PMID:1321309 PMID:11082157 |
| cortisol | increases response to substance | ISO | RGD:1352097 | 6480464 | POMC protein results in increased susceptibility to Hydrocortisone | CTD | PMID:3015460 |
| cyanamide | multiple interactions | ISO | RGD:3366 | 6480464 | [Ethanol co-treated with Cyanamide] results in increased expression of POMC mRNA | CTD | PMID:11139417 |
| cycloheximide | multiple interactions | ISO | RGD:3366 | 6480464 | Cycloheximide inhibits the reaction [POMC protein modified form results in increased chemical synthesis of Adrenal Cortex Hormones] | CTD | PMID:2993719 |
| cyclophosphamide | increases expression | ISO | RGD:3366 | 6480464 | Cyclophosphamide results in increased expression of POMC protein | CTD | PMID:15276878 |
| cyproheptadine | decreases secretion | ISO | RGD:1352097 | 6480464 | Cyproheptadine results in decreased secretion of POMC protein | CTD | PMID:642945 |
| D-glucose | decreases expression | ISO | RGD:3366 | 6480464 | Glucose results in decreased expression of POMC mRNA | CTD | PMID:18627777 |
| D-glucose | multiple interactions | EXP | | 6480464 | POMC inhibits the reaction [INS1 results in increased uptake of Glucose] | CTD | PMID:18310442 |
| DDE | multiple interactions | EXP | | 6480464 | [Dichlorodiphenyl Dichloroethylene co-treated with beta-hexachlorocyclohexane] results in decreased expression of POMC mRNA | CTD | PMID:16758953 |
| DDT | multiple interactions | ISO | RGD:1352097 | 6480464 | [Lindane co-treated with DDT] results in increased expression of POMC | CTD | PMID:16329587 |
| dehydroepiandrosterone sulfate | increases abundance | ISO | RGD:1352097 | 6480464 | POMC results in increased abundance of Dehydroepiandrosterone Sulfate | CTD | PMID:2161262 |
| deisopropylatrazine | increases secretion | ISO | RGD:3366 | 6480464 | 6-deisopropylatrazine results in increased secretion of POMC protein modified form | CTD | PMID:19690231 PMID:19710361 |
| deisopropylatrazine | increases secretion | ISO | RGD:3366 | 6480464 | 6-deisopropylatrazine results in increased secretion of POMC protein modified form | CTD | PMID:19710361 PMID:19690231 |
| Delta(9)-tetrahydrocannabinol | increases expression | ISO | RGD:3366 | 6480464 | Tetrahydrocannabinol results in increased expression of POMC mRNA | CTD | PMID:11528220 PMID:9128838 |
| Delta(9)-tetrahydrocannabinol | multiple interactions | ISO | RGD:3366 | 6480464 | Estradiol affects the reaction [Tetrahydrocannabinol results in increased expression of POMC mRNA] | CTD | PMID:11528220 |
| Delta(9)-tetrahydrocannabinol | affects expression | ISO | RGD:3366 | 6480464 | Tetrahydrocannabinol affects the expression of POMC mRNA | CTD | PMID:12829401 |
| Delta(9)-tetrahydrocannabinol | increases expression | ISO | RGD:3366 | 6480464 | Tetrahydrocannabinol results in increased expression of POMC | CTD | PMID:10219981 |
| dexamethasone | multiple interactions | ISO | RGD:1352097 | 6480464 | Dexamethasone inhibits the reaction [Crack Cocaine results in increased secretion of POMC protein] | CTD | PMID:10780258 |
| dexamethasone | affects response to substance | ISO | RGD:1352097 | 6480464 | POMC affects the susceptibility to Dexamethasone | CTD | PMID:1459535 |
| dexamethasone | decreases expression | ISO | RGD:1352097 | 6480464 | Dexamethasone results in decreased expression of POMC protein | CTD | PMID:174842 |
| dexamethasone | decreases secretion | ISO | RGD:1352097 | 6480464 | Dexamethasone results in decreased secretion of POMC protein | CTD | PMID:9253312 |
| dexamethasone | multiple interactions | ISO | RGD:1352097 | 6480464 | Dexamethasone inhibits the reaction [POMC protein results in increased abundance of Aldosterone] | CTD | PMID:3015796 |
| diazoxide | increases secretion | ISO | RGD:3366 | 6480464 | Isoproterenol results in increased secretion of POMC protein alternative form | CTD | PMID:10898105 |
| dichlorvos | multiple interactions | ISO | RGD:3366 | 6480464 | Dichlorvos inhibits the reaction [POMC protein modified form results in increased chemical synthesis of Adrenal Cortex Hormones] | CTD | PMID:2993719 |
| dichlorvos | increases secretion | ISO | RGD:3366 | 6480464 | Dichlorvos results in increased secretion of POMC protein modified form | CTD | PMID:6245657 |
| diethyl ether | increases secretion | ISO | RGD:3366 | 6480464 | Ether, Ethyl results in increased secretion of POMC protein | CTD | PMID:2846107 |
| dimethyl sulfoxide | decreases expression | EXP | | 6480464 | Dimethyl Sulfoxide results in decreased expression of POMC protein | CTD | PMID:15680486 |
| dinitrogen oxide | increases secretion | ISO | RGD:3366 | 6480464 | Nitrous Oxide results in increased secretion of POMC protein | CTD | PMID:2846107 |
| dioxygen | increases secretion | ISO | RGD:3366 | 6480464 | Oxygen results in increased secretion of POMC protein | CTD | PMID:2846107 |
| disodium cromoglycate | multiple interactions | ISO | RGD:3366 | 6480464 | Cromolyn Sodium inhibits the reaction [POMC results in increased secretion of Corticosterone] | CTD | PMID:1659878 |
| disulfiram | decreases expression | ISO | RGD:3366 | 6480464 | Disulfiram results in decreased expression of POMC protein alternative form | CTD | PMID:8246921 |
| docetaxel anhydrous | increases expression | ISO | RGD:3366 | 6480464 | docetaxel results in increased expression of POMC mRNA | CTD | PMID:22902858 |
| docetaxel anhydrous | multiple interactions | ISO | RGD:3366 | 6480464 | celecoxib inhibits the reaction [docetaxel results in increased expression of POMC mRNA]; more ... | CTD | PMID:22902858 |
| dodecane | increases expression | ISO | RGD:3366 | 6480464 | n-dodecane results in increased expression of POMC protein modified form | CTD | PMID:19152832 |
| dopamine | multiple interactions | EXP | | 6480464 | POMC protein affects the reaction [Nicotine results in increased abundance of Dopamine] | CTD | PMID:15689546 |
| ethanol | decreases expression | ISO | RGD:1352097 | 6480464 | Ethanol results in decreased expression of POMC mRNA | CTD | PMID:17934066 |
| ethanol | multiple interactions | ISO | RGD:3366 | 6480464 | Ethanol results in increased expression of and results in increased secretion of POMC protein; more ... | CTD | PMID:20021565 |
| ethanol | affects response to substance | ISO | RGD:3366 | 6480464 | POMC protein affects the susceptibility to Ethanol | CTD | PMID:20021565 |
| ethanol | increases expression | ISO | RGD:3366 | 6480464 | Ethanol results in increased expression of POMC mRNA | CTD | PMID:7704432 PMID:16925589 |
| ethanol | increases expression | ISO | RGD:3366 | 6480464 | Ethanol results in increased expression of POMC protein | CTD | PMID:7704432 more ... |
| ethanol | increases expression | ISO | RGD:3366 | 6480464 | Ethanol results in increased expression of POMC protein | CTD | PMID:16925589 more ... |
| ethanol | increases expression | ISO | RGD:3366 | 6480464 | Ethanol results in increased expression of POMC protein | CTD | PMID:9610951 more ... |
| ethanol | increases expression | ISO | RGD:3366 | 6480464 | Ethanol results in increased expression of POMC mRNA | CTD | PMID:16925589 PMID:7704432 |
| ethanol | decreases secretion | ISO | RGD:3366 | 6480464 | Ethanol results in decreased secretion of POMC protein alternative form | CTD | PMID:12746300 |
| ethanol | multiple interactions | ISO | RGD:3366 | 6480464 | [Ethanol co-treated with Cyanamide] results in increased expression of POMC mRNA | CTD | PMID:11139417 |
| ethanol | multiple interactions | ISO | RGD:3366 | 6480464 | astressin B inhibits the reaction [Ethanol results in decreased secretion of POMC protein alternative form]; more ... | CTD | PMID:12746300 |
| ethanol | multiple interactions | ISO | RGD:1352097 | 6480464 | fomepizole inhibits the reaction [Ethanol results in decreased expression of POMC mRNA] | CTD | PMID:17934066 |
| fentanyl | decreases expression | ISO | RGD:1352097 | 6480464 | Fentanyl results in decreased expression of POMC protein alternative form | CTD | PMID:20084599 |
| fentanyl | multiple interactions | ISO | RGD:1352097 | 6480464 | [Fentanyl co-treated with Morphine] results in decreased expression of POMC protein alternative form | CTD | PMID:20084599 |
| fludrocortisone | multiple interactions | ISO | RGD:1352097 | 6480464 | [Fludrocortisone binds to and results in increased activity of NR3C2 protein] which results in decreased expression of POMC protein | CTD | PMID:16566900 |
| fluoxetine | increases expression | ISO | RGD:3366 | 6480464 | Fluoxetine results in increased expression of POMC protein; more ... | CTD | PMID:18359080 |
| fluoxetine | decreases expression | ISO | RGD:3366 | 6480464 | Fluoxetine results in decreased expression of POMC mRNA | CTD | PMID:15936043 PMID:16042082 |
| fomepizole | multiple interactions | ISO | RGD:1352097 | 6480464 | fomepizole inhibits the reaction [Ethanol results in decreased expression of POMC mRNA] | CTD | PMID:17934066 |
| formaldehyde | increases expression | EXP | | 6480464 | Formaldehyde results in increased expression of POMC mRNA; more ... | CTD | PMID:15805735 PMID:15196973 |
| formaldehyde | increases expression | EXP | | 6480464 | Formaldehyde results in increased expression of POMC mRNA; more ... | CTD | PMID:15196973 PMID:15805735 |
| fructose | decreases expression | ISO | RGD:3366 | 6480464 | Fructose results in decreased expression of POMC mRNA | CTD | PMID:18627777 |
| fulvestrant | multiple interactions | ISO | RGD:3366 | 6480464 | fulvestrant inhibits the reaction [nonylphenol promotes the reaction [POMC protein modified form results in increased secretion of Corticosterone]] | CTD | PMID:20837582 |
| gamma-hexachlorocyclohexane | multiple interactions | ISO | RGD:1352097 | 6480464 | [Lindane co-treated with DDT] results in increased expression of POMC | CTD | PMID:16329587 |
| genistein | decreases expression | ISO | RGD:1352097 | 6480464 | Genistein results in decreased expression of POMC mRNA | CTD | PMID:20706672 |
| glucose | decreases expression | ISO | RGD:3366 | 6480464 | Glucose results in decreased expression of POMC mRNA | CTD | PMID:18627777 |
| glucose | multiple interactions | EXP | | 6480464 | POMC inhibits the reaction [INS1 results in increased uptake of Glucose] | CTD | PMID:18310442 |
| glycerol | increases secretion | ISO | RGD:1352097 | 6480464 | POMC protein alternative form results in increased secretion of Glycerol | CTD | PMID:8429757 |
| halothane | increases secretion | ISO | RGD:3366 | 6480464 | Halothane results in increased secretion of POMC protein | CTD | PMID:2846107 |
| imipramine | multiple interactions | ISO | RGD:1352097 | 6480464 | Imipramine inhibits the reaction [Buspirone results in increased expression of POMC protein] | CTD | PMID:19762159 |
| indomethacin | multiple interactions | ISO | RGD:3366 | 6480464 | Indomethacin inhibits the reaction [Phenylephrine results in increased secretion of POMC protein alternative form]; more ... | CTD | PMID:10898105 |
| isoprenaline | increases secretion | ISO | RGD:3366 | 6480464 | Isoproterenol results in increased secretion of POMC protein alternative form | CTD | PMID:10898105 |
| lansoprazole | increases expression | ISO | RGD:1352097 | 6480464 | lansoprazole results in increased expression of POMC protein | CTD | PMID:16524691 |
| lidocaine | multiple interactions | ISO | RGD:3366 | 6480464 | Lidocaine inhibits the reaction [Capsaicin results in increased secretion of POMC protein] | CTD | PMID:8925284 |
| magnesium atom | multiple interactions | ISO | RGD:3366 | 6480464 | Phentolamine inhibits the reaction [POMC results in increased uptake of Magnesium] | CTD | PMID:191614 |
| magnesium atom | increases uptake | ISO | RGD:3366 | 6480464 | POMC results in increased uptake of Magnesium | CTD | PMID:191614 |
| magnesium atom | decreases uptake | ISO | RGD:3366 | 6480464 | POMC modified form results in decreased uptake of Magnesium | CTD | PMID:191614 |
| melatonin | multiple interactions | ISO | RGD:3366 | 6480464 | [Melatonin co-treated with p-Chloroamphetamine] results in increased expression of POMC protein | CTD | PMID:11478929 |
| methamidophos | increases expression | ISO | RGD:3366 | 6480464 | methamidophos results in increased expression of POMC protein alternative form | CTD | PMID:11048668 |
| metyrapone | increases expression | ISO | RGD:1352097 | 6480464 | Metyrapone results in increased expression of POMC protein | CTD | PMID:16566900 |
| metyrapone | increases expression | ISO | RGD:3366 | 6480464 | Metyrapone results in increased expression of POMC | CTD | PMID:638031 |
| morphine | multiple interactions | ISO | RGD:1352097 | 6480464 | [Fentanyl co-treated with Morphine] results in decreased expression of POMC protein alternative form | CTD | PMID:20084599 |
| morphine | multiple interactions | ISO | RGD:3366 | 6480464 | Capsaicin inhibits the reaction [[Morphine co-treated with Naloxone] results in increased secretion of POMC protein]; more ... | CTD | PMID:2846107 |
| morphine | multiple interactions | EXP | | 6480464 | [Zymosan co-treated with Morphine] results in increased expression of POMC mRNA | CTD | PMID:15979727 |
| morphine | increases expression | EXP | | 6480464 | Morphine results in increased expression of POMC mRNA | CTD | PMID:20144693 |
| naloxone | multiple interactions | ISO | RGD:1352097 | 6480464 | [Clonidine results in increased expression of POMC protein] which results in increased susceptibility to Naloxone | CTD | PMID:6089027 |
| naloxone | multiple interactions | ISO | RGD:3366 | 6480464 | Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein]; more ... | CTD | PMID:2846107 |
| naloxone | increases expression | ISO | RGD:1352097 | 6480464 | Naloxone results in increased expression of POMC protein alternative form | CTD | PMID:2255747 |
| naloxone | multiple interactions | ISO | RGD:1352097 | 6480464 | Naloxone binds to and results in increased activity of POMC protein alternative form | CTD | PMID:3157294 |
| naproxen | multiple interactions | ISO | RGD:3366 | 6480464 | [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of POMC protein]; more ... | CTD | PMID:22150557 |
| nickel atom | increases expression | ISO | RGD:3366 | 6480464 | Nickel results in increased expression of POMC mRNA | CTD | PMID:20682304 |
| nitric oxide | multiple interactions | ISO | RGD:3366 | 6480464 | CRH protein affects the reaction [Nitric Oxide results in increased secretion of POMC protein alternative form] | CTD | PMID:10460269 |
| nitric oxide | decreases abundance | ISO | RGD:3366 | 6480464 | POMC protein results in decreased abundance of Nitric Oxide | CTD | PMID:11193135 PMID:11703388 |
| nitric oxide | decreases abundance | ISO | RGD:3366 | 6480464 | POMC protein results in decreased abundance of Nitric Oxide | CTD | PMID:11703388 PMID:11193135 |
| nitric oxide | increases secretion | ISO | RGD:3366 | 6480464 | Nitric Oxide results in increased secretion of POMC protein alternative form | CTD | PMID:10460269 |
| nitroprusside | multiple interactions | ISO | RGD:3366 | 6480464 | Corticosterone inhibits the reaction [Nitroprusside results in increased secretion of POMC protein] | CTD | PMID:3015567 |
| nitroprusside | multiple interactions | ISO | RGD:3366 | 6480464 | Nitroprusside inhibits the reaction [POMC protein modified form results in increased secretion of Corticosterone]; more ... | CTD | PMID:20837582 |
| nitroprusside | increases secretion | ISO | RGD:3366 | 6480464 | Nitroprusside results in increased secretion of POMC protein | CTD | PMID:3015567 |
| nonane | increases expression | ISO | RGD:3366 | 6480464 | nonane results in increased expression of POMC protein modified form | CTD | PMID:19152832 |
| olanzapine | decreases expression | ISO | RGD:3366 | 6480464 | olanzapine results in decreased expression of POMC protein | CTD | PMID:21695181 |
| paracetamol | decreases expression | ISO | RGD:1352097 | 6480464 | Acetaminophen results in decreased expression of POMC protein | CTD | PMID:16449370 |
| pentobarbital | multiple interactions | ISO | RGD:3366 | 6480464 | Muscimol promotes the reaction [Pentobarbital results in decreased expression of POMC mRNA] | CTD | PMID:7937335 |
| pentobarbital | multiple interactions | ISO | RGD:3366 | 6480464 | Pentobarbital inhibits the reaction [Acetylcholine results in increased expression of POMC protein] | CTD | PMID:7588217 |
| pentobarbital | decreases expression | ISO | RGD:3366 | 6480464 | Pentobarbital results in decreased expression of POMC mRNA | CTD | PMID:7937335 |
| phenylephrine | increases response to substance | ISO | RGD:1352097 | 6480464 | POMC protein results in increased susceptibility to Phenylephrine | CTD | PMID:3015460 PMID:2822310 |
| phenylephrine | increases response to substance | ISO | RGD:1352097 | 6480464 | POMC protein results in increased susceptibility to Phenylephrine | CTD | PMID:2822310 PMID:3015460 |
| phenylephrine | increases secretion | ISO | RGD:3366 | 6480464 | Phenylephrine results in increased secretion of POMC protein alternative form | CTD | PMID:10898105 |
| phenylephrine | multiple interactions | ISO | RGD:3366 | 6480464 | Indomethacin inhibits the reaction [Phenylephrine results in increased secretion of POMC protein alternative form] | CTD | PMID:10898105 |
| potassium atom | affects abundance | ISO | RGD:3366 | 6480464 | POMC protein affects the abundance of Potassium | CTD | PMID:9535146 PMID:2157753 |
| potassium atom | affects abundance | ISO | RGD:3366 | 6480464 | POMC protein affects the abundance of Potassium | CTD | PMID:2157753 PMID:9535146 |
| potassium atom | multiple interactions | ISO | RGD:3366 | 6480464 | Spironolactone inhibits the reaction [POMC protein modified form results in decreased abundance of Potassium] | CTD | PMID:10100081 |
| potassium atom | decreases abundance | ISO | RGD:3366 | 6480464 | POMC protein modified form results in decreased abundance of Potassium | CTD | PMID:10100081 |
| prednisolone | decreases expression | ISO | RGD:3366 | 6480464 | Prednisolone results in decreased expression of POMC protein modified form | CTD | PMID:9625448 |
| prednisolone | multiple interactions | ISO | RGD:3366 | 6480464 | sairei-to inhibits the reaction [Prednisolone results in decreased expression of POMC protein modified form] | CTD | PMID:9625448 |
| prednisone | decreases expression | ISO | RGD:1352097 | 6480464 | Prednisone results in decreased expression of POMC protein modified form | CTD | PMID:1977371 |
| progesterone | multiple interactions | EXP | | 6480464 | [benzylphosphonic acid results in decreased activity of POMC protein] which results in decreased chemical synthesis of Progesterone; more ... | CTD | PMID:12530643 |
| propazine | increases secretion | ISO | RGD:3366 | 6480464 | propazine results in increased secretion of POMC protein modified form | CTD | PMID:19690231 |
| pyridoxal 5'-phosphate | decreases secretion | EXP | | 6480464 | Pyridoxal Phosphate results in decreased secretion of POMC protein | CTD | PMID:16690808 |
| rabeprazole sodium | increases expression | ISO | RGD:1352097 | 6480464 | rabeprazole results in increased expression of POMC protein | CTD | PMID:16524691 |
| reserpine | increases expression | ISO | RGD:3366 | 6480464 | Reserpine results in increased expression of POMC protein alternative form | CTD | PMID:8479280 |
| reserpine | multiple interactions | ISO | RGD:3366 | 6480464 | POMC protein alternative form inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA] | CTD | PMID:20504635 |
| reserpine | increases expression | ISO | RGD:3366 | 6480464 | Reserpine results in increased expression of POMC mRNA | CTD | PMID:20504635 |
| simazine | increases secretion | ISO | RGD:3366 | 6480464 | Simazine results in increased secretion of POMC protein modified form | CTD | PMID:19690231 |
| sodium atom | affects abundance | ISO | RGD:3366 | 6480464 | POMC protein affects the abundance of Sodium | CTD | PMID:9535146 PMID:2157753 |
| sodium atom | affects abundance | ISO | RGD:3366 | 6480464 | POMC protein affects the abundance of Sodium | CTD | PMID:2157753 PMID:9535146 |
| sodium atom | increases abundance | ISO | RGD:3366 | 6480464 | POMC protein modified form results in increased abundance of Sodium | CTD | PMID:10100081 |
| sodium atom | multiple interactions | ISO | RGD:3366 | 6480464 | Spironolactone inhibits the reaction [POMC protein modified form results in increased abundance of Sodium] | CTD | PMID:10100081 |
| spironolactone | multiple interactions | ISO | RGD:3366 | 6480464 | Spironolactone inhibits the reaction [POMC protein modified form results in decreased abundance of Potassium]; more ... | CTD | PMID:10100081 |
| streptozocin | multiple interactions | ISO | RGD:3366 | 6480464 | INS protein inhibits the reaction [Streptozocin results in decreased expression of POMC mRNA] | CTD | PMID:20219977 |
| streptozocin | decreases expression | ISO | RGD:3366 | 6480464 | Streptozocin results in decreased expression of POMC mRNA | CTD | PMID:20219977 |
| sufentanil | decreases expression | ISO | RGD:1352097 | 6480464 | Sufentanil results in decreased expression of POMC protein modified form | CTD | PMID:15714323 |
| sumatriptan | decreases expression | ISO | RGD:1352097 | 6480464 | Sumatriptan results in decreased expression of POMC protein modified form | CTD | PMID:7640145 |
| sumatriptan | multiple interactions | ISO | RGD:3366 | 6480464 | Sumatriptan inhibits the reaction [Capsaicin results in increased expression of POMC protein]; more ... | CTD | PMID:22150557 |
| superoxide | increases abundance | ISO | RGD:3366 | 6480464 | POMC protein results in increased abundance of Superoxides | CTD | PMID:16620303 |
| tetrachloromethane | multiple interactions | EXP | | 6480464 | POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]; more ... | CTD | PMID:16508911 |
| tetracycline | increases expression | EXP | | 6480464 | Tetracycline results in increased expression of POMC mRNA | CTD | PMID:16917069 |
| theophylline | multiple interactions | ISO | RGD:3366 | 6480464 | INS1 protein inhibits the reaction [[Theophylline co-treated with POMC protein] results in increased abundance of Cyclic AMP] | CTD | PMID:4306506 |
| thioacetamide | multiple interactions | EXP | | 6480464 | POMC protein alternative form inhibits the reaction [Thioacetamide results in increased degradation of NFKBIA protein]; more ... | CTD | PMID:15313186 |
| thioacetamide | multiple interactions | EXP | | 6480464 | POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of TNF mRNA] | CTD | PMID:15313186 PMID:16511523 |
| thioacetamide | multiple interactions | EXP | | 6480464 | POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of TNF mRNA] | CTD | PMID:16511523 PMID:15313186 |
| thioacetamide | multiple interactions | EXP | | 6480464 | POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein]; more ... | CTD | PMID:16511523 |
| toluene | increases expression | ISO | RGD:3366 | 6480464 | Toluene results in increased expression of POMC protein | CTD | PMID:15707876 |
| urethane | increases secretion | ISO | RGD:3366 | 6480464 | Urethane results in increased secretion of POMC protein | CTD | PMID:2846107 |
| valproic acid | affects expression | ISO | RGD:3366 | 6480464 | Valproic Acid affects the expression of POMC protein | CTD | PMID:7816191 |