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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:immune response-regulating signaling pathway
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Accession:GO:0002764 term browser browse the term
Definition:The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response.
Synonyms:exact_synonym: immune response-regulating signalling pathway

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immune response-regulating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsh cathepsin H involved_in ISO (PMID:16822283) UniProt PMID:16822283 NCBI chrNW_004624941:82,209...98,156
Ensembl chrNW_004624941:82,209...98,182 		JBrowse link
G Lat2 linker for activation of T cells family member 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624740:13,745,949...13,764,869 JBrowse link
antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:10587647) UniProt PMID:10587647 NCBI chrNW_004624746:11,660,859...11,695,991
Ensembl chrNW_004624746:11,660,426...11,695,988 		JBrowse link
G Cd19 CD19 molecule involved_in ISO (PMID:1373518) UniProt PMID:1373518 NCBI chrNW_004624782:12,844,148...12,850,770
Ensembl chrNW_004624782:12,845,432...12,850,576 		JBrowse link
G Lax1 lymphocyte transmembrane adaptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15843560) TreeGrafter
MGI
Ensembl		 PMID:15843560 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624807:7,182,094...7,192,412
Ensembl chrNW_004624807:7,183,832...7,192,320 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624740:15,266,759...15,289,420
Ensembl chrNW_004624740:15,266,653...15,278,165 		JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) BHF-UCL PMID:15214043 NCBI chrNW_004624832:5,050,222...5,068,565
Ensembl chrNW_004624832:5,050,222...5,055,506 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:23728777) MGI PMID:23728777 NCBI chrNW_004624789:15,612,311...15,623,878
Ensembl chrNW_004624789:15,612,335...15,624,152 		JBrowse link
B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:11120811), (PMID:19228876) MGI PMID:11120811 PMID:19228876 NCBI chrNW_004624760:4,878,811...5,032,719
Ensembl chrNW_004624760:4,878,556...5,031,491 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO (PMID:9020138) UniProt PMID:9020138 NCBI chrNW_004624746:11,660,859...11,695,991
Ensembl chrNW_004624746:11,660,426...11,695,988 		JBrowse link
G Bcl2 BCL2 apoptosis regulator involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344 		JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:23555801)
(PMID:876631)		 ARUK-UCL
UniProt		 PMID:876631 PMID:23555801 NCBI chrNW_004624758:25,129,922...25,180,180
Ensembl chrNW_004624758:25,129,853...25,181,761 		JBrowse link
G Blnk B cell linker involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:7,565,169...7,681,102 JBrowse link
G Bmx BMX non-receptor tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624829:297,187...344,555
Ensembl chrNW_004624829:297,351...344,164 		JBrowse link
G Btk Bruton tyrosine kinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624902:1,173,101...1,216,662
Ensembl chrNW_004624902:1,182,682...1,216,171 		JBrowse link
G Cd19 CD19 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9254656) TreeGrafter
MGI		 PMID:9254656 GO_REF:0000118 NCBI chrNW_004624782:12,844,148...12,850,770
Ensembl chrNW_004624782:12,845,432...12,850,576 		JBrowse link
G Cd38 CD38 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624755:16,035,412...16,093,610
Ensembl chrNW_004624755:16,034,771...16,093,866 		JBrowse link
G Cd79a CD79a molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1373499), (PMID:8626447) TreeGrafter
MGI
InterPro
Ensembl		 PMID:1373499 PMID:8626447 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624907:803,439...806,879
Ensembl chrNW_004624907:803,359...806,897 		JBrowse link
G Cd79b CD79b molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1373499), (PMID:8626447) TreeGrafter
MGI
InterPro		 PMID:1373499 PMID:8626447 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624849:1,429,446...1,432,835
Ensembl chrNW_004624849:1,429,912...1,432,955 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624765:12,449,205...12,454,324
Ensembl chrNW_004624765:12,449,205...12,454,324 		JBrowse link
G Fcrl5 Fc receptor like 5 acts_upstream_of ISO (PMID:23509253) MGI PMID:23509253 NCBI chrNW_004624794:3,217,505...3,248,486 JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624801:5,143,239...5,219,136
Ensembl chrNW_004624801:5,143,141...5,219,244 		JBrowse link
G Itk IL2 inducible T cell kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624733:32,125,005...32,198,901
Ensembl chrNW_004624733:32,127,388...32,198,869 		JBrowse link
G Klhl6 kelch like family member 6 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624730:72,916,601...72,972,204 JBrowse link
G Lat2 linker for activation of T cells family member 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624740:13,745,949...13,764,869 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7499277) TreeGrafter
MGI		 PMID:7499277 GO_REF:0000118 NCBI chrNW_004624764:15,469,582...15,495,351
Ensembl chrNW_004624764:15,472,685...15,495,351 		JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 acts_upstream_of_or_within ISO (PMID:16249387) MGI PMID:16249387 NCBI chrNW_004624741:29,390,743...29,393,457 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:23509253)
(PMID:7499277)		 MGI PMID:7499277 PMID:23509253 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (PMID:9254656) MGI PMID:9254656 NCBI chrNW_004624747:1,296,062...1,389,674
Ensembl chrNW_004624747:1,296,221...1,389,757 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:3829850|PMID:18955699) UniProt PMID:18955699 MGI:3829850 NCBI chrNW_004624743:8,072,871...8,235,174
Ensembl chrNW_004624743:8,072,673...8,235,252 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624904:2,508,576...2,575,505
Ensembl chrNW_004624904:2,508,799...2,578,609 		JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15143214) TreeGrafter
MGI		 PMID:15143214 GO_REF:0000118 NCBI chrNW_004624752:6,298,251...6,356,562
Ensembl chrNW_004624752:6,324,181...6,357,066 		JBrowse link
G Nfatc2 nuclear factor of activated T cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624790:4,366,440...4,484,279
Ensembl chrNW_004624790:4,366,406...4,484,432 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:17367755) MGI PMID:17367755 NCBI chrNW_004624830:5,334,273...5,430,887
Ensembl chrNW_004624830:5,333,616...5,408,723 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624838:1,384,337...1,387,602
Ensembl chrNW_004624838:1,384,204...1,390,205 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:17367755) MGI PMID:17367755 NCBI chrNW_004624789:15,612,311...15,623,878
Ensembl chrNW_004624789:15,612,335...15,624,152 		JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (PMID:15509800)
(MGI:1861532|PMID:10925250)
(PMID:11606584)		 ARUK-UCL
UniProt		 PMID:10925250 PMID:11606584 PMID:15509800 MGI:1861532 NCBI chrNW_004624746:5,678,057...5,824,663
Ensembl chrNW_004624746:5,682,666...5,821,855 		JBrowse link
G Plekha1 pleckstrin homology domain containing A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:24,299,199...24,365,459 JBrowse link
G Prkcb protein kinase C beta involved_in ISO (MGI:3626015|PMID:12118249) UniProt PMID:12118249 MGI:3626015 NCBI chrNW_004624782:8,974,995...9,287,609
Ensembl chrNW_004624782:8,974,765...9,287,702 		JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9254656)
(PMID:23509253)		 Ensembl
MGI		 PMID:9254656 PMID:23509253 GO_REF:0000107 NCBI chrNW_004624860:3,580,225...3,595,403
Ensembl chrNW_004624860:3,580,560...3,595,090 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within
involved_in		 ISO (PMID:9254656)
(PMID:7499277)
(MGI:3687418|PMID:8692271)		 MGI
UniProt		 PMID:7499277 PMID:8692271 PMID:9254656 MGI:3687418 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
G Rftn1 raftlin, lipid raft linker 1 involved_in ISO (PMID:12805216) UniProt PMID:12805216 NCBI chrNW_004624821:1,561,845...1,763,654
Ensembl chrNW_004624821:1,562,778...1,751,345 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:9233773)
(PMID:10872802)		 UniProt
MGI		 PMID:9233773 PMID:10872802 NCBI chrNW_004624740:15,266,759...15,289,420
Ensembl chrNW_004624740:15,266,653...15,278,165 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in ISO (PMID:24043312) MGI PMID:24043312 NCBI chrNW_004624738:20,466,120...20,591,966
Ensembl chrNW_004624738:20,466,117...20,591,910 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:7499277), (PMID:8626447) MGI
TreeGrafter
Ensembl		 PMID:7499277 PMID:8626447 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391 		JBrowse link
G Tec tec protein tyrosine kinase involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624761:18,695,168...18,824,045
Ensembl chrNW_004624761:18,695,177...18,822,078 		JBrowse link
G Txk TXK tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624761:18,841,795...18,897,564
Ensembl chrNW_004624761:18,841,795...18,897,458 		JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 involved_in ISO (PMID:17875758) UniProt PMID:17875758 NCBI chrNW_004624772:3,604,553...4,022,986
Ensembl chrNW_004624772:3,604,165...4,022,990 		JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (PMID:15294986) AgBase PMID:15294986 NCBI chrNW_004624743:33,372,023...33,374,438
Ensembl chrNW_004624743:33,367,898...33,373,922 		JBrowse link
G Clec7a C-type lectin domain containing 7A acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chrNW_004624752:26,871,556...26,885,778
Ensembl chrNW_004624752:26,871,292...26,891,910 		JBrowse link
G Fcn1 ficolin 1 involved_in ISO (PMID:21037097) UniProt PMID:21037097 NCBI chrNW_004624760:2,743,996...2,751,116
Ensembl chrNW_004624760:2,743,996...2,751,110 		JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISO (PMID:21037097) UniProt PMID:21037097 NCBI chrNW_004624794:8,140,629...8,155,313
Ensembl chrNW_004624794:8,140,629...8,155,258 		JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO (PMID:15294986) AgBase PMID:15294986 NCBI chrNW_004624842:1,306,299...1,332,269
Ensembl chrNW_004624842:1,301,831...1,332,346 		JBrowse link
G Mbl2 mannose binding lectin 2 involved_in ISO (PMID:22966085) ComplexPortal PMID:22966085 NCBI chrNW_004624791:10,881,319...10,886,294
Ensembl chrNW_004624791:10,881,268...10,886,297 		JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833 		JBrowse link
cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35322803), (PMID:35438208), (PMID:35460603) UniProt PMID:32911482 PMID:32912999 PMID:33542149 PMID:35322803 PMID:35438208 More... NCBI chrNW_004624819:587,739...680,618
Ensembl chrNW_004624819:643,045...680,684 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (MGI:7548257|PMID:37832545)
(PMID:25636800), (PMID:30842659), (PMID:30842662), (PMID:35388221), (PMID:37832545)		 UniProt PMID:25636800 PMID:30842659 PMID:30842662 PMID:35388221 PMID:37832545 MGI:7548257 NCBI chrNW_004624743:32,277,197...32,283,346
Ensembl chrNW_004624743:32,273,385...32,283,235 		JBrowse link
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3ar1 complement C3a receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624860:5,196,621...5,204,686
Ensembl chrNW_004624860:5,197,619...5,199,043 		JBrowse link
G C5ar1 complement C5a receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624832:6,413,169...6,423,394
Ensembl chrNW_004624832:6,414,587...6,423,394 		JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chrNW_004624832:6,403,002...6,411,399
Ensembl chrNW_004624832:6,403,621...6,404,631 		JBrowse link
complement receptor mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (MGI:6189359|PMID:22632727) ARUK-UCL PMID:22632727 MGI:6189359 NCBI chrNW_004624828:3,773,816...3,798,077
Ensembl chrNW_004624828:3,770,221...3,797,946 		JBrowse link
G C3ar1 complement C3a receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624860:5,196,621...5,204,686
Ensembl chrNW_004624860:5,197,619...5,199,043 		JBrowse link
G C5ar1 complement C5a receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:6,413,169...6,423,394
Ensembl chrNW_004624832:6,414,587...6,423,394 		JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:6,403,002...6,411,399
Ensembl chrNW_004624832:6,403,621...6,404,631 		JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624747:11,553,268...11,601,105 JBrowse link
G Cmklr2 chemerin chemokine-like receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624765:9,898,536...9,953,815
Ensembl chrNW_004624765:9,952,440...9,953,507 		JBrowse link
G Fpr1 formyl peptide receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,305,274...3,309,964
Ensembl chrNW_004624832:3,308,802...3,309,845 		JBrowse link
G Fpr2 formyl peptide receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,275,365...3,282,308 JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:15907827), (PMID:19135435) UniProt PMID:15907827 PMID:19135435 NCBI chrNW_004624756:2,505,937...2,569,618
Ensembl chrNW_004624756:2,505,945...2,569,464 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (MGI:6189359|PMID:22632727) ARUK-UCL PMID:22632727 MGI:6189359 NCBI chrNW_004624782:14,316,505...14,367,841
Ensembl chrNW_004624782:14,318,499...14,367,922 		JBrowse link
G LOC101706116 N-formyl peptide receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,238,627...3,239,711
Ensembl chrNW_004624832:3,238,627...3,239,685 		JBrowse link
G LOC106007553 N-formyl peptide receptor 2-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624832:3,255,571...3,262,458 JBrowse link
cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpk1 alpha kinase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624838:6,273,398...6,288,363
Ensembl chrNW_004624838:6,229,899...6,287,920 		JBrowse link
G Becn1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:1,386,154...1,406,314
Ensembl chrNW_004624795:1,385,756...1,405,714 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:23258413) UniProt PMID:23258413 NCBI chrNW_004624819:587,739...680,618
Ensembl chrNW_004624819:643,045...680,684 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (PMID:19211564) UniProt PMID:19211564 NCBI chrNW_004624795:1,787,958...1,793,475
Ensembl chrNW_004624795:1,787,958...1,794,692 		JBrowse link
G Ipo5 importin 5 involved_in ISO (PMID:31340999) UniProt PMID:31340999 NCBI chrNW_004624793:12,971,397...13,004,126
Ensembl chrNW_004624793:12,969,459...13,004,139 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624832:4,611,445...4,616,319
Ensembl chrNW_004624832:4,612,374...4,616,276 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:21931555) UniProt PMID:21931555 NCBI chrNW_004624766:21,850,211...21,853,189 JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:16125763), (PMID:20451243) UniProt PMID:16125763 PMID:20451243 NCBI chrNW_004624741:4,936,556...4,951,081
Ensembl chrNW_004624741:4,939,040...4,954,058 		JBrowse link
G Rigi RNA sensor RIG-I involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624736:37,134,718...37,204,543
Ensembl chrNW_004624736:37,133,059...37,197,218 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:23910378), (PMID:35388221) UniProt PMID:23910378 PMID:35388221 NCBI chrNW_004624743:32,277,197...32,283,346
Ensembl chrNW_004624743:32,273,385...32,283,235 		JBrowse link
G Tbk1 TANK binding kinase 1 involved_in ISO (PMID:29441066) UniProt PMID:29441066 NCBI chrNW_004624802:3,861,821...3,914,061
Ensembl chrNW_004624802:3,862,709...3,914,028 		JBrowse link
G Tifa TRAF interacting protein with forkhead associated domain involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624838:6,160,712...6,167,408 JBrowse link
G Traf3ip3 TRAF3 interacting protein 3 involved_in ISO (PMID:31390091) UniProt PMID:31390091 NCBI chrNW_004624807:2,214,288...2,239,449
Ensembl chrNW_004624807:2,214,449...2,235,048 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:20501938), (PMID:23015697) UniProt PMID:20501938 PMID:23015697 NCBI chrNW_004624767:10,729,766...10,803,253
Ensembl chrNW_004624767:10,729,413...10,748,455 		JBrowse link
G Trim25 tripartite motif containing 25 involved_in ISO (PMID:17392790) UniProt PMID:17392790 NCBI chrNW_004624795:11,967,908...11,986,707
Ensembl chrNW_004624795:11,971,610...11,986,608 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:22607805) UniProt PMID:22607805 NCBI chrNW_004624786:4,080,650...4,135,200
Ensembl chrNW_004624786:4,080,427...4,135,459 		JBrowse link
endolysosomal toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Washc4 WASH complex subunit 4 acts_upstream_of_or_within ISO (PMID:33749590) MGI PMID:33749590 NCBI chrNW_004624750:3,830,646...3,883,458 JBrowse link
Fc receptor mediated inhibitory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:3703139|PMID:16272347) UniProt PMID:16272347 MGI:3703139 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902 		JBrowse link
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902 		JBrowse link
Fc receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene, receptor tyrosine kinase involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chrNW_004624761:14,733,912...14,831,428 JBrowse link
G Pigr polymeric immunoglobulin receptor involved_in ISO (PMID:22022593) UniProt PMID:22022593 NCBI chrNW_004624807:4,545,508...4,562,976
Ensembl chrNW_004624807:4,545,481...4,563,357 		JBrowse link
Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig involved_in ISO (PMID:16735691) UniProt PMID:16735691 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034 		JBrowse link
G Fer FER tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624743:26,663,440...27,097,771
Ensembl chrNW_004624743:26,694,465...27,091,250 		JBrowse link
Fc-gamma receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd247 CD247 molecule involved_in ISO (PMID:8478617) UniProt PMID:8478617 NCBI chrNW_004624826:5,504,676...5,574,037
Ensembl chrNW_004624826:5,505,569...5,573,783 		JBrowse link
G Clec4e C-type lectin domain family 4 member E involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23602766) Ensembl
MGI		 PMID:23602766 GO_REF:0000107 NCBI chrNW_004624860:4,108,782...4,113,693
Ensembl chrNW_004624860:4,108,640...4,113,839 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:23602766) MGI PMID:23602766 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb involved_in ISO (PMID:2142460) ARUK-UCL PMID:2142460 NCBI chrNW_004624826:97,605...112,101 JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa involved_in ISO (PMID:23024279), (PMID:8478617) UniProt PMID:8478617 PMID:23024279 NCBI chrNW_004624826:51,387...59,117 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:8478617) UniProt PMID:8478617 NCBI chrNW_004624764:15,469,582...15,495,351
Ensembl chrNW_004624764:15,472,685...15,495,351 		JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myo1g myosin IG involved_in ISO (MGI:5586792|PMID:23038771) UniProt PMID:23038771 MGI:5586792 NCBI chrNW_004624740:7,362,653...7,374,041
Ensembl chrNW_004624740:7,363,143...7,373,713 		JBrowse link
immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag6 BAG cochaperone 6 involved_in ISO (PMID:18852879) UniProt PMID:18852879 NCBI chrNW_004624754:24,559,483...24,571,073
Ensembl chrNW_004624754:24,559,801...24,571,073 		JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in ISO (PMID:18852879) UniProt PMID:18852879 NCBI chrNW_004624754:24,607,623...24,612,716 JBrowse link
immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zc3h12a zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:20,224,919...20,234,108
Ensembl chrNW_004624764:20,224,906...20,234,629 		JBrowse link
immune response-inhibiting signal transduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il20rb interleukin 20 receptor subunit beta acts_upstream_of_or_within ISO (PMID:19124723) MGI PMID:19124723 NCBI chrNW_004624730:13,371,898...13,408,927
Ensembl chrNW_004624730:13,378,478...13,409,676 		JBrowse link
immune response-regulating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btla B and T lymphocyte associated acts_upstream_of_or_within ISO (PMID:15568026) MGI PMID:15568026 NCBI chrNW_004624731:36,097,083...36,131,498
Ensembl chrNW_004624731:36,097,156...36,129,669 		JBrowse link
G Cd40 CD40 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15240714) TreeGrafter
MGI		 PMID:15240714 GO_REF:0000118 NCBI chrNW_004624790:8,475,640...8,485,927
Ensembl chrNW_004624790:8,476,158...8,485,856 		JBrowse link
G Fpr2 formyl peptide receptor 2 involved_in ISO (PMID:25505240) ARUK-UCL PMID:25505240 NCBI chrNW_004624832:3,275,365...3,282,308 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:894972|PMID:9252121) UniProt PMID:9252121 MGI:894972 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 ISO RGD PMID:1531699 RGD:2306006 NCBI chrNW_004624828:3,838,464...3,896,698
Ensembl chrNW_004624828:3,838,706...3,897,080 		JBrowse link
innate immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr4 toll like receptor 4 ISO RGD PMID:19226379 RGD:2312509 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifih1 interferon induced with helicase C domain 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624732:3,187,791...3,248,795
Ensembl chrNW_004624732:3,187,791...3,250,981 		JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chrNW_004624788:15,158,920...15,294,785 JBrowse link
MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) BHF-UCL PMID:16148103 NCBI chrNW_004624889:2,736,727...2,746,333 JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12872135)
(PMID:12719478)
(PMID:14764662)		 Ensembl
MGI
InterPro		 PMID:12719478 PMID:12872135 PMID:14764662 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004624731:2,677,259...2,681,408
Ensembl chrNW_004624731:2,677,290...2,681,489 		JBrowse link
G Tlr2 toll like receptor 2 acts_upstream_of_or_within ISO (PMID:12719478) MGI PMID:12719478 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833 		JBrowse link
G Tlr4 toll like receptor 4 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (MGI:4438693|PMID:20037584)
(PMID:20037584)		 ARUK-UCL
ComplexPortal		 PMID:20037584 MGI:4438693 NCBI chrNW_004624840:7,323,022...7,349,334 JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 involved_in ISO (MGI:5305352|PMID:22011580) UniProt PMID:22011580 MGI:5305352 NCBI chrNW_004624733:40,964,020...41,006,381 JBrowse link
MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) MGI PMID:19265123 NCBI chrNW_004624788:15,158,920...15,294,785 JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 acts_upstream_of_or_within ISO (PMID:12872135)
(PMID:12855817)		 MGI PMID:12855817 PMID:12872135 NCBI chrNW_004624828:4,964,199...4,973,465
Ensembl chrNW_004624828:4,971,093...4,973,198 		JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 involved_in ISO (PMID:17088249) UniProt PMID:17088249 NCBI chrNW_004624777:1,124,389...1,222,450
Ensembl chrNW_004624777:1,124,204...1,158,324 		JBrowse link
natural killer cell inhibitory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec12b C-type lectin domain family 12 member B involved_in ISO (PMID:17562706) UniProt PMID:17562706 NCBI chrNW_004624752:26,790,063...26,796,279 JBrowse link
negative regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trim11 tripartite motif containing 11 involved_in ISO (PMID:27498865) UniProt PMID:27498865 NCBI chrNW_004624937:1,100,297...1,109,017
Ensembl chrNW_004624937:1,100,297...1,109,027 		JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624794:8,211,232...8,224,020
Ensembl chrNW_004624794:8,211,094...8,221,866 		JBrowse link
G Cd300a CD300a molecule involved_in ISO (PMID:21482706) UniProt PMID:21482706 NCBI chrNW_004624801:4,404,376...4,420,836
Ensembl chrNW_004624801:4,404,262...4,421,097 		JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb involved_in ISO (PMID:24169826) ARUK-UCL PMID:24169826 NCBI chrNW_004624826:97,605...112,101 JBrowse link
G Fcrl5 Fc receptor like 5 acts_upstream_of_or_within ISO (PMID:23509253) MGI PMID:23509253 NCBI chrNW_004624794:3,217,505...3,248,486 JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (MGI:5896692|PMID:28039360) UniProt PMID:28039360 MGI:5896692 NCBI chrNW_004624786:9,938,384...9,941,210
Ensembl chrNW_004624786:9,938,384...9,941,235 		JBrowse link
G Lpxn leupaxin involved_in ISO (MGI:3722965|PMID:17640867)
(PMID:17640867)		 UniProt PMID:17640867 MGI:3722965 NCBI chrNW_004624864:1,815,056...1,852,041
Ensembl chrNW_004624864:1,818,614...1,852,503 		JBrowse link
G Plcl2 phospholipase C like 2 acts_upstream_of_or_within ISO (PMID:14517301) MGI PMID:14517301 NCBI chrNW_004624821:2,132,075...2,316,624
Ensembl chrNW_004624821:2,131,851...2,315,934 		JBrowse link
negative regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:507,880...525,295
Ensembl chrNW_004624734:509,368...525,295 		JBrowse link
G Aurkb aurora kinase B involved_in ISO (PMID:33542149) UniProt PMID:33542149 NCBI chrNW_004624786:10,769,797...10,775,142
Ensembl chrNW_004624786:10,765,610...10,775,112 		JBrowse link
G Banf1 BAF nuclear assembly factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:20,435,143...20,436,830
Ensembl chrNW_004624767:20,434,955...20,436,640 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:32911482), (PMID:32912999) UniProt PMID:32911482 PMID:32912999 NCBI chrNW_004624819:587,739...680,618
Ensembl chrNW_004624819:643,045...680,684 		JBrowse link
G Irgm immunity related GTPase M involved_in ISO (PMID:32715615) UniProt PMID:32715615 NCBI chrNW_004624733:41,241,488...41,248,162 JBrowse link
G Lyplal1 lysophospholipase like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624835:3,023,151...3,052,826
Ensembl chrNW_004624835:3,022,311...3,052,724 		JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 involved_in ISO (PMID:35460603) UniProt PMID:35460603 NCBI chrNW_004624807:446,662...478,571
Ensembl chrNW_004624807:446,647...479,069 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 involved_in ISO (PMID:35322803) UniProt PMID:35322803 NCBI chrNW_004624904:1,553,253...1,579,212
Ensembl chrNW_004624904:1,555,635...1,578,982 		JBrowse link
G Ppp6c protein phosphatase 6 catalytic subunit involved_in ISO (PMID:32474700) UniProt PMID:32474700 NCBI chrNW_004624760:10,025,102...10,073,164
Ensembl chrNW_004624760:10,024,575...10,074,329 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:33273464) UniProt PMID:33273464 NCBI chrNW_004624735:7,534,483...7,702,079
Ensembl chrNW_004624735:7,534,506...7,700,305 		JBrowse link
G Trex1 three prime repair exonuclease 1 involved_in ISO (PMID:33476576) UniProt PMID:33476576 NCBI chrNW_004624730:2,431,270...2,433,010
Ensembl chrNW_004624730:2,431,999...2,432,959 		JBrowse link
G Zdhhc18 zinc finger DHHC-type palmitoyltransferase 18 involved_in ISO (PMID:35438208) UniProt PMID:35438208 NCBI chrNW_004624764:10,822,540...10,853,842 JBrowse link
negative regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itch itchy E3 ubiquitin protein ligase involved_in ISO (PMID:27736772) UniProt PMID:27736772 NCBI chrNW_004624842:4,840,848...4,977,785
Ensembl chrNW_004624842:4,842,419...4,935,699 		JBrowse link
G Tarbp2 TARBP2 subunit of RISC loading complex involved_in ISO (PMID:30927622) UniProt PMID:30927622 NCBI chrNW_004624904:1,598,422...1,603,494
Ensembl chrNW_004624904:1,597,428...1,603,504 		JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO (PMID:27736772) UniProt PMID:27736772 NCBI chrNW_004624739:2,800,453...2,894,355
Ensembl chrNW_004624739:2,801,301...2,885,094 		JBrowse link
G Tspan6 tetraspanin 6 involved_in ISO (PMID:22908223) UniProt PMID:22908223 NCBI chrNW_004624902:1,977,700...1,985,004
Ensembl chrNW_004624902:1,978,467...1,986,303 		JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (MGI:6271154|PMID:25568335) UniProt PMID:25568335 MGI:6271154 NCBI chrNW_004624822:31,175...74,252
Ensembl chrNW_004624822:33,880...74,308 		JBrowse link
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:9,239,119...9,243,617
Ensembl chrNW_004624786:9,239,177...9,243,961 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (PMID:21187438) UniProt PMID:21187438 NCBI chrNW_004624795:1,787,958...1,793,475
Ensembl chrNW_004624795:1,787,958...1,794,692 		JBrowse link
G Riok3 RIO kinase 3 involved_in ISO (PMID:25865883) UniProt PMID:25865883 NCBI chrNW_004624770:8,675,501...8,696,999
Ensembl chrNW_004624770:8,675,294...8,697,620 		JBrowse link
G Tkfc triokinase and FMN cyclase involved_in ISO (PMID:17600090) UniProt PMID:17600090 NCBI chrNW_004624926:862,339...870,936
Ensembl chrNW_004624926:862,339...869,926 		JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300a molecule involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chrNW_004624801:4,404,376...4,420,836
Ensembl chrNW_004624801:4,404,262...4,421,097 		JBrowse link
G Cd300lf CD300 molecule like family member f involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chrNW_004624801:4,573,010...4,587,632
Ensembl chrNW_004624801:4,573,010...4,587,592 		JBrowse link
negative regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sarm1 sterile alpha and TIR motif containing 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624786:974,785...1,001,810
Ensembl chrNW_004624786:974,876...997,956 		JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd17a abhydrolase domain containing 17A, depalmitoylase involved_in ISO (PMID:38092000) UniProt PMID:38092000 NCBI chrNW_004624828:6,915,126...6,923,433
Ensembl chrNW_004624828:6,917,061...6,923,433 		JBrowse link
G Cptp ceramide-1-phosphate transfer protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624818:8,283,925...8,287,410
Ensembl chrNW_004624818:8,283,926...8,287,274 		JBrowse link
G Csnk1a1 casein kinase 1 alpha 1 involved_in ISO (MGI:6787653|PMID:34615873) UniProt PMID:34615873 MGI:6787653 NCBI chrNW_004624774:8,815,021...8,862,657
Ensembl chrNW_004624774:8,815,023...8,862,878 		JBrowse link
G Fbxl2 F-box and leucine rich repeat protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624788:11,253,912...11,350,045
Ensembl chrNW_004624788:11,253,934...11,349,137 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624880:2,070,410...2,075,069
Ensembl chrNW_004624880:2,070,523...2,079,421 		JBrowse link
G Irgm immunity related GTPase M involved_in ISO (MGI:6282153|PMID:30612879)
(PMID:30612879)		 UniProt PMID:30612879 MGI:6282153 NCBI chrNW_004624733:41,241,488...41,248,162 JBrowse link
G Lamp2 lysosomal associated membrane protein 2 involved_in ISO (PMID:36586411) UniProt PMID:36586411 NCBI chrNW_004624931:297,864...343,314
Ensembl chrNW_004624931:298,328...343,915 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624824:1,035,172...1,047,632
Ensembl chrNW_004624824:1,035,094...1,047,678 		JBrowse link
G Nlrc3 NLR family CARD domain containing 3 involved_in ISO (PMID:25277106) UniProt PMID:25277106 NCBI chrNW_004624824:1,356,587...1,375,403
Ensembl chrNW_004624824:1,357,326...1,375,688 		JBrowse link
G Sirt2 sirtuin 2 acts_upstream_of_or_within ISO (PMID:23502856) MGI PMID:23502856 NCBI chrNW_004624794:12,239,363...12,259,561
Ensembl chrNW_004624794:12,235,263...12,259,276 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISO (MGI:6391726|PMID:29887864)
(PMID:32514138)		 ARUK-UCL PMID:29887864 PMID:32514138 MGI:6391726 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231 		JBrowse link
G Zdhhc12 zinc finger DHHC-type palmitoyltransferase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624760:6,273,989...6,276,788
Ensembl chrNW_004624760:6,273,994...6,276,776 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbin erbb2 interacting protein involved_in ISO (MGI:5640951|PMID:16203728)
(PMID:16203728)		 UniProt PMID:16203728 MGI:5640951 NCBI chrNW_004624815:3,765,261...3,901,309
Ensembl chrNW_004624815:3,768,207...3,852,815 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990 		JBrowse link
G Znrf4 zinc and ring finger 4 involved_in ISO (PMID:28656966) UniProt PMID:28656966 NCBI chrNW_004624828:4,633,434...4,635,366 JBrowse link
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:9,239,119...9,243,617
Ensembl chrNW_004624786:9,239,177...9,243,961 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624795:1,787,958...1,793,475
Ensembl chrNW_004624795:1,787,958...1,794,692 		JBrowse link
G Gpatch3 G-patch domain containing 3 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624764:10,879,342...10,889,175
Ensembl chrNW_004624764:10,879,556...10,889,146 		JBrowse link
G Nlrx1 NLR family member X1 acts_upstream_of_or_within ISO (PMID:21703540) MGI PMID:21703540 NCBI chrNW_004624784:14,549,926...14,564,028
Ensembl chrNW_004624784:14,549,834...14,563,398 		JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor involved_in ISO (PMID:26471729) UniProt PMID:26471729 NCBI chrNW_004624801:10,531,107...10,589,502
Ensembl chrNW_004624801:10,533,064...10,589,096 		JBrowse link
G Rnf125 ring finger protein 125 involved_in ISO (PMID:17460044), (PMID:26471729) UniProt PMID:17460044 PMID:26471729 NCBI chrNW_004624770:909,808...942,386 JBrowse link
G Sec14l1 SEC14 like lipid binding 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624801:6,890,278...6,942,724
Ensembl chrNW_004624801:6,890,134...6,945,443 		JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 involved_in ISO (PMID:26471729) UniProt PMID:26471729 NCBI chrNW_004624747:110,090...132,145
Ensembl chrNW_004624747:110,090...132,097 		JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase involved_in ISO (PMID:38225265) UniProt PMID:38225265 NCBI chrNW_004624831:868,417...1,065,591
Ensembl chrNW_004624831:868,563...1,060,248 		JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO (PMID:14738763) MGI PMID:14738763 NCBI chrNW_004624731:43,803,743...44,018,682
Ensembl chrNW_004624731:43,803,768...44,015,870 		JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISO (MGI:2672999|PMID:12883552) UniProt PMID:12883552 MGI:2672999 NCBI chrNW_004624767:2,173,774...2,210,304
Ensembl chrNW_004624767:2,173,272...2,210,279 		JBrowse link
G Dusp22 dual specificity phosphatase 22 involved_in
acts_upstream_of_or_within		 ISO (PMID:38225265)
(PMID:24714587)		 UniProt
MGI		 PMID:24714587 PMID:38225265 NCBI chrNW_004624756:23,968,148...24,017,340
Ensembl chrNW_004624756:23,968,017...24,017,332 		JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624795:994,103...1,001,697 JBrowse link
G Elf1 E74 like ETS transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14738763) Ensembl
MGI		 PMID:14738763 GO_REF:0000107 NCBI chrNW_004624748:13,987,001...14,090,451
Ensembl chrNW_004624748:14,017,621...14,091,619 		JBrowse link
G Ezr ezrin involved_in ISO (PMID:20551903) UniProt PMID:20551903 NCBI chrNW_004624929:827,275...873,743
Ensembl chrNW_004624929:826,531...873,572 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) ARUK-UCL PMID:18619870 MGI:3803048 NCBI chrNW_004624764:14,208,144...14,277,208
Ensembl chrNW_004624764:14,207,094...14,228,135 		JBrowse link
G Lgals3 galectin 3 involved_in ISO (MGI:4355752|PMID:19706535) BHF-UCL PMID:19706535 MGI:4355752 NCBI chrNW_004624731:14,300,138...14,307,843
Ensembl chrNW_004624731:14,298,201...14,304,637 		JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO (PMID:12970181) MGI PMID:12970181 NCBI chrNW_004624750:18,562,270...18,710,397
Ensembl chrNW_004624750:18,562,221...18,705,540 		JBrowse link
G Prnp prion protein (Kanno blood group) involved_in ISO (MGI:4943618|PMID:20145049) BHF-UCL PMID:20145049 MGI:4943618 NCBI chrNW_004624741:5,785,139...5,802,162
Ensembl chrNW_004624741:5,785,158...5,802,162 		JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (MGI:5320871|PMID:22080863) UniProt PMID:22080863 MGI:5320871 NCBI chrNW_004624770:19,808,400...19,877,494
Ensembl chrNW_004624770:19,808,400...19,876,503 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in ISO (PMID:18056643) UniProt PMID:18056643 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990 		JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9064344) MGI
Ensembl		 PMID:9064344 GO_REF:0000107 NCBI chrNW_004624860:3,580,225...3,595,403
Ensembl chrNW_004624860:3,580,560...3,595,090 		JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J involved_in ISO (PMID:11259588), (PMID:9780142)
(MGI:4942249|PMID:12913111)
(PMID:12913111)		 UniProt PMID:9780142 PMID:11259588 PMID:12913111 MGI:4942249 NCBI chrNW_004624767:942,786...1,051,112
Ensembl chrNW_004624767:945,553...1,051,138 		JBrowse link
G Sh2d1a SH2 domain containing 1A involved_in ISO (PMID:9774102) UniProt PMID:9774102 NCBI chrNW_004624797:3,120,123...3,142,564
Ensembl chrNW_004624797:3,120,123...3,142,564 		JBrowse link
G Sla2 Src like adaptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624842:2,853,183...2,882,269
Ensembl chrNW_004624842:2,853,144...2,881,116 		JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in ISO (MGI:1096761|PMID:9285719) UniProt PMID:9285719 MGI:1096761 NCBI chrNW_004624784:14,779,533...14,784,315
Ensembl chrNW_004624784:14,780,698...14,784,897 		JBrowse link
G Ubash3a ubiquitin associated and SH3 domain containing A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14738763) TreeGrafter
MGI		 PMID:14738763 GO_REF:0000118 NCBI chrNW_004624745:28,026,274...28,057,922 JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) UniProt PMID:23609450 MGI:5490396 NCBI chrNW_004624751:23,478,263...23,488,834
Ensembl chrNW_004624751:23,478,096...23,483,521 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:4456928|PMID:20385881) UniProt PMID:20385881 MGI:4456928 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (MGI:6162316|PMID:26599367)
(PMID:26599367)		 UniProt PMID:26599367 MGI:6162316 NCBI chrNW_004624839:4,908,861...5,000,218
Ensembl chrNW_004624839:4,908,639...5,000,677 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:15220916) MGI PMID:15220916 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chrNW_004624840:7,323,022...7,349,334 JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6695864|PMID:31134514) ARUK-UCL PMID:31134514 MGI:6695864 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231 		JBrowse link
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) UniProt PMID:19865078 NCBI chrNW_004624869:1,326,605...1,337,195 JBrowse link
G Rnf170 ring finger protein 170 involved_in ISO (PMID:31076723) UniProt PMID:31076723 NCBI chrNW_004624780:67,160...127,620
Ensembl chrNW_004624780:66,049...126,383 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in ISO (MGI:5619743|PMID:21695056) CACAO PMID:21695056 MGI:5619743 NCBI chrNW_004624809:6,434,842...6,487,442
Ensembl chrNW_004624809:6,436,658...6,487,251 		JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (MGI:5490396|PMID:23609450) UniProt PMID:23609450 MGI:5490396 NCBI chrNW_004624751:23,478,263...23,488,834
Ensembl chrNW_004624751:23,478,096...23,483,521 		JBrowse link
G Bpifb1 BPI fold containing family B member 1 involved_in ISO (PMID:21900486) UniProt PMID:21900486 NCBI chrNW_004624842:5,951,202...5,972,212
Ensembl chrNW_004624842:5,951,203...5,972,212 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO (PMID:19948740) UniProt PMID:19948740 NCBI chrNW_004624760:13,472,500...13,658,070
Ensembl chrNW_004624760:13,472,672...13,657,930 		JBrowse link
G LOC101722352 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:19412184) UniProt PMID:19412184 NCBI chrNW_004624733:6,304,454...6,341,827 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:4456928|PMID:20385881) UniProt PMID:20385881 MGI:4456928 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28609714) UniProt PMID:28609714 NCBI chrNW_004624839:4,908,861...5,000,218
Ensembl chrNW_004624839:4,908,639...5,000,677 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:3,102,424...3,109,497
Ensembl chrNW_004624795:3,102,439...3,109,497 		JBrowse link
G Rab7b RAB7B, member RAS oncogene family involved_in ISO (MGI:3834524|PMID:17395780) UniProt PMID:17395780 MGI:3834524 NCBI chrNW_004624807:5,307,361...5,334,578
Ensembl chrNW_004624807:5,307,440...5,334,945 		JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO (PMID:31281713) UniProt PMID:31281713 NCBI chrNW_004624733:42,689,454...42,700,916
Ensembl chrNW_004624733:42,691,841...42,700,916 		JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO (PMID:28898289) UniProt PMID:28898289 NCBI chrNW_004624739:2,800,453...2,894,355
Ensembl chrNW_004624739:2,801,301...2,885,094 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6152919|PMID:29407460)
(MGI:6695864|PMID:31134514)		 ARUK-UCL PMID:29407460 PMID:31134514 MGI:6152919 MGI:6695864 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231 		JBrowse link
G Trim32 tripartite motif containing 32 involved_in ISO (PMID:28898289) UniProt PMID:28898289 NCBI chrNW_004624760:18,577,764...18,600,869
Ensembl chrNW_004624760:18,585,279...18,599,659 		JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gramd4 GRAM domain containing 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624752:3,328,132...3,401,027
Ensembl chrNW_004624752:3,330,905...3,400,977 		JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO (PMID:14716310) UniProt PMID:14716310 NCBI chrNW_004624764:22,542,892...22,577,077
Ensembl chrNW_004624764:22,543,857...22,577,121 		JBrowse link
G Ptprs protein tyrosine phosphatase receptor type S involved_in ISO (PMID:26231120) UniProt PMID:26231120 NCBI chrNW_004624828:4,688,555...4,764,805
Ensembl chrNW_004624828:4,716,249...4,764,614 		JBrowse link
G Rab7b RAB7B, member RAS oncogene family involved_in ISO (MGI:4355098|PMID:19587007) UniProt PMID:19587007 MGI:4355098 NCBI chrNW_004624807:5,307,361...5,334,578
Ensembl chrNW_004624807:5,307,440...5,334,945 		JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin beta 2 involved_in ISO (MGI:3662828|PMID:16378096) UniProt PMID:16378096 MGI:3662828 NCBI chrNW_004624786:8,568,102...8,576,445
Ensembl chrNW_004624786:8,568,198...8,577,914 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) UniProt PMID:20829348 NCBI chrNW_004624828:6,313,165...6,322,837
Ensembl chrNW_004624828:6,313,867...6,322,764 		JBrowse link
G Gpr108 G protein-coupled receptor 108 involved_in ISO (MGI:6220977|PMID:30332431) UniProt PMID:30332431 MGI:6220977 NCBI chrNW_004624828:3,805,151...3,812,113
Ensembl chrNW_004624828:3,805,366...3,812,055 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (MGI:5896692|PMID:28039360) UniProt PMID:28039360 MGI:5896692 NCBI chrNW_004624786:9,938,384...9,941,210
Ensembl chrNW_004624786:9,938,384...9,941,235 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927) BHF-UCL PMID:12150927 MGI:2183694 NCBI chrNW_004624802:2,042,486...2,098,921
Ensembl chrNW_004624802:2,047,409...2,098,545 		JBrowse link
G Irf4 interferon regulatory factor 4 acts_upstream_of_or_within ISO (PMID:16236719) MGI PMID:16236719 NCBI chrNW_004624756:23,917,111...23,931,482
Ensembl chrNW_004624756:23,918,323...23,931,501 		JBrowse link
G Lgr4 leucine rich repeat containing G protein-coupled receptor 4 involved_in ISO (MGI:5499954|PMID:23589304) UniProt PMID:23589304 MGI:5499954 NCBI chrNW_004624766:17,110,809...17,147,585
Ensembl chrNW_004624766:17,112,909...17,147,785 		JBrowse link
G Lrrc14 leucine rich repeat containing 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624735:12,337,564...12,345,260 JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624754:24,639,757...24,652,059
Ensembl chrNW_004624754:24,639,860...24,649,968 		JBrowse link
G Nlrp6 NLR family pyrin domain containing 6 acts_upstream_of_or_within ISO (PMID:22763455) MGI PMID:22763455 NCBI chrNW_004624766:22,143,405...22,150,903 JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624853:4,091,591...4,145,344
Ensembl chrNW_004624853:4,091,316...4,140,201 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 involved_in ISO (MGI:4821539|PMID:20584979) UniProt PMID:20584979 MGI:4821539 NCBI chrNW_004624824:279,893...383,220
Ensembl chrNW_004624824:293,374...383,156 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (MGI:5487531|PMID:20728433) UniProt PMID:20728433 MGI:5487531 NCBI chrNW_004624737:8,021,478...8,154,543
Ensembl chrNW_004624737:8,022,836...8,154,422 		JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004624772:17,099,593...17,196,258
Ensembl chrNW_004624772:17,104,189...17,196,326 		JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase acid like 3B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:11,785,739...11,807,351
Ensembl chrNW_004624764:11,785,640...11,807,084 		JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in ISO (MGI:3773763|PMID:18083102) UniProt PMID:18083102 MGI:3773763 NCBI chrNW_004624804:8,711,487...8,729,025
Ensembl chrNW_004624804:8,710,821...8,728,072 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004624786:4,080,650...4,135,200
Ensembl chrNW_004624786:4,080,427...4,135,459 		JBrowse link
NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of ISO (PMID:23502856) MGI PMID:23502856 NCBI chrNW_004624754:25,058,312...25,069,052
Ensembl chrNW_004624754:25,058,204...25,069,561 		JBrowse link
G Kcnj8 potassium inwardly rectifying channel subfamily J member 8 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:28928055) MGI
Ensembl		 PMID:28928055 GO_REF:0000107 NCBI chrNW_004624752:16,939,289...16,945,692
Ensembl chrNW_004624752:16,939,384...16,946,723 		JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in
acts_upstream_of_or_within		 ISO (MGI:5492224|PMID:23582325), (MGI:5792478|PMID:27043286), (MGI:5913002|PMID:28716882), (MGI:5921465|PMID:28656979), (MGI:6106673|PMID:28943315), (MGI:6260219|PMID:30487600), (MGI:6787653|PMID:34615873), (MGI:6844859|PMID:34861190), (MGI:6859739|PMID:28465465), (PMID:26173909)
(PMID:17483456), (PMID:23582325), (PMID:25686105), (PMID:27043286), (PMID:27432880), (PMID:28465465), (PMID:28656979), (PMID:28943315), (PMID:30487600), (PMID:31189953), (PMID:33231615), (PMID:34554188), (PMID:34615873), (PMID:35114687), (PMID:35254907), (PMID:35559676), (PMID:36442502)
(PMID:22753929)		 UniProt
MGI		 PMID:17483456 PMID:22753929 PMID:23582325 PMID:25686105 PMID:26173909 More... MGI:5492224 MGI:5792478 MGI:5913002 MGI:5921465 MGI:6106673 MGI:6260219 MGI:6787653 MGI:6844859 MGI:6859739 NCBI chrNW_004624937:564,191...584,470 JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:27432880) UniProt PMID:27432880 NCBI chrNW_004624782:14,247,333...14,249,861
Ensembl chrNW_004624782:14,247,864...14,249,000 		JBrowse link
G Sirt2 sirtuin 2 acts_upstream_of ISO (PMID:23502856) MGI PMID:23502856 NCBI chrNW_004624794:12,239,363...12,259,561
Ensembl chrNW_004624794:12,235,263...12,259,276 		JBrowse link
NLRP6 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlrp6 NLR family pyrin domain containing 6 involved_in ISO (MGI:6706628|PMID:32424362), (MGI:6833928|PMID:34678144)
(PMID:30674671), (PMID:31932628), (PMID:34678144)		 UniProt PMID:30674671 PMID:31932628 PMID:32424362 PMID:34678144 MGI:6706628 MGI:6833928 NCBI chrNW_004624766:22,143,405...22,150,903 JBrowse link
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf34 ring finger protein 34 involved_in ISO (PMID:25012219) UniProt PMID:25012219 NCBI chrNW_004624747:21,904,652...21,920,579
Ensembl chrNW_004624747:21,904,667...21,920,778 		JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18261938) MGI
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chrNW_004624838:1,384,337...1,387,602
Ensembl chrNW_004624838:1,384,204...1,390,205 		JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 involved_in ISO (MGI:6210191|PMID:27007849)
(PMID:11058605), (PMID:12791997), (PMID:12796777)		 UniProt PMID:11058605 PMID:12791997 PMID:12796777 PMID:27007849 MGI:6210191 NCBI chrNW_004624739:285,791...339,752
Ensembl chrNW_004624739:285,689...341,956 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:29452636), (PMID:30279485)
(PMID:11894098)		 UniProt
MGI		 PMID:11894098 PMID:29452636 PMID:30279485 NCBI chrNW_004624744:2,194,339...2,227,498
Ensembl chrNW_004624744:2,201,319...2,226,890 		JBrowse link
G Tlr4 toll like receptor 4 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inava innate immunity activator involved_in ISO (PMID:28436939) UniProt PMID:28436939 NCBI chrNW_004624807:9,718,307...9,738,282
Ensembl chrNW_004624807:9,718,307...9,738,148 		JBrowse link
G Irgm immunity related GTPase M involved_in ISO (PMID:25891078) UniProt PMID:25891078 NCBI chrNW_004624733:41,241,488...41,248,162 JBrowse link
G Lacc1 laccase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624748:11,150,678...11,194,794
Ensembl chrNW_004624748:11,187,316...11,194,841 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chrNW_004624838:1,384,337...1,387,602
Ensembl chrNW_004624838:1,384,204...1,390,205 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:12527755)
(PMID:23892723)
(PMID:12626759), (PMID:15044951), (PMID:17355968), (PMID:23806334), (PMID:31649195)
(MGI:6210191|PMID:27007849)
(MGI:3529429|PMID:15692052)		 MGI
UniProt		 PMID:12527755 PMID:12626759 PMID:15044951 PMID:15692052 PMID:17355968 More... MGI:3529429 MGI:6210191 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103 		JBrowse link
G Otulin OTU deubiquitinase with linear linkage specificity involved_in ISO (PMID:23806334) UniProt PMID:23806334 NCBI chrNW_004624751:11,676,932...11,703,143
Ensembl chrNW_004624751:11,676,850...11,702,061 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12527755) MGI
Ensembl		 PMID:12527755 GO_REF:0000107 NCBI chrNW_004624767:20,732,813...20,742,016
Ensembl chrNW_004624767:20,732,938...20,741,272 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 ISO (MGI:7484276|PMID:17947236)
(PMID:11894098)
(PMID:16824733), (PMID:17355968), (PMID:17562858), (PMID:23806334), (PMID:28545134), (PMID:29452636), (PMID:30026309), (PMID:30279485), (PMID:30478312)		 UniProt
MGI		 PMID:11894098 PMID:16824733 PMID:17355968 PMID:17562858 PMID:17947236 More... MGI:7484276 NCBI chrNW_004624744:2,194,339...2,227,498
Ensembl chrNW_004624744:2,201,319...2,226,890 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:18261938) MGI
Ensembl		 PMID:18261938 GO_REF:0000107 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:23258413) UniProt PMID:23258413 NCBI chrNW_004624819:587,739...680,618
Ensembl chrNW_004624819:643,045...680,684 		JBrowse link
G Clec4e C-type lectin domain family 4 member E involved_in ISO (PMID:24101491) UniProt PMID:24101491 NCBI chrNW_004624860:4,108,782...4,113,693
Ensembl chrNW_004624860:4,108,640...4,113,839 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) UniProt PMID:28436939 NCBI chrNW_004624807:9,718,307...9,738,282
Ensembl chrNW_004624807:9,718,307...9,738,148 		JBrowse link
G Lacc1 laccase domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624748:11,150,678...11,194,794
Ensembl chrNW_004624748:11,187,316...11,194,841 		JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 involved_in ISO (PMID:31649195) UniProt PMID:31649195 NCBI chrNW_004624739:285,791...339,752
Ensembl chrNW_004624739:285,689...341,956 		JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 involved_in ISO (PMID:31649195) UniProt PMID:31649195 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103 		JBrowse link
G Rnf144a ring finger protein 144A involved_in ISO (PMID:37955227) UniProt PMID:37955227 NCBI chrNW_004624846:3,297,444...3,393,473
Ensembl chrNW_004624846:3,300,960...3,378,372 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:23910378) UniProt PMID:23910378 NCBI chrNW_004624743:32,277,197...32,283,346
Ensembl chrNW_004624743:32,273,385...32,283,235 		JBrowse link
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbp5 guanylate binding protein 5 involved_in ISO (MGI:5774627|PMID:25774716), (MGI:5774628|PMID:25774715) UniProt PMID:25774715 PMID:25774716 MGI:5774627 MGI:5774628 NCBI chrNW_004624742:8,324,902...8,335,965 JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (MGI:3687418|PMID:8692271) UniProt PMID:8692271 MGI:3687418 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:15,192,446...15,210,923
Ensembl chrNW_004624767:15,192,452...15,210,922 		JBrowse link
G Cmtm3 CKLF like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO (PMID:15196959) MGI PMID:15196959 NCBI chrNW_004624746:19,830,839...19,840,350
Ensembl chrNW_004624746:19,830,839...19,839,430 		JBrowse link
G Foxp1 forkhead box P1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624773:5,543,529...6,076,522
Ensembl chrNW_004624773:5,543,536...5,883,131 		JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624752:6,298,251...6,356,562
Ensembl chrNW_004624752:6,324,181...6,357,066 		JBrowse link
G Prkcb protein kinase C beta involved_in ISO (MGI:3700457|PMID:16301747) UniProt PMID:16301747 MGI:3700457 NCBI chrNW_004624782:8,974,995...9,287,609
Ensembl chrNW_004624782:8,974,765...9,287,702 		JBrowse link
G Prkch protein kinase C eta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:39,620,690...39,830,281
Ensembl chrNW_004624734:39,619,273...39,830,353 		JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO (PMID:25074919) MGI PMID:25074919 NCBI chrNW_004624854:1,163,025...1,280,717 JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624761:1,361,271...1,409,548
Ensembl chrNW_004624761:1,361,498...1,409,674 		JBrowse link
positive regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:37832545) UniProt PMID:37832545 NCBI chrNW_004624799:3,554,644...3,623,317
Ensembl chrNW_004624799:3,554,678...3,622,289 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 involved_in ISO (PMID:36745868) UniProt PMID:36745868 NCBI chrNW_004624745:30,793,114...30,811,944
Ensembl chrNW_004624745:30,794,024...30,811,944 		JBrowse link
G Tab1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 involved_in ISO (PMID:37832545) UniProt PMID:37832545 NCBI chrNW_004624752:8,912,467...8,937,313
Ensembl chrNW_004624752:8,913,900...8,937,329 		JBrowse link
G Zdhhc9 zinc finger DHHC-type palmitoyltransferase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624797:9,027,316...9,060,321
Ensembl chrNW_004624797:9,023,833...9,060,855 		JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624806:11,324,239...11,390,487
Ensembl chrNW_004624806:11,324,344...11,388,206 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISO RGD PMID:16177098 RGD:1578516 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in ISO (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
G Ptprj protein tyrosine phosphatase receptor type J involved_in ISO (MGI:3774343|PMID:18249142) ARUK-UCL PMID:18249142 MGI:3774343 NCBI chrNW_004624767:942,786...1,051,112
Ensembl chrNW_004624767:945,553...1,051,138 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family ISO RGD PMID:18832707 RGD:9835043 NCBI chrNW_004624772:7,340,152...7,425,218
Ensembl chrNW_004624772:7,368,653...7,424,938 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 ISO RGD PMID:18832707 RGD:9835043 NCBI chrNW_004624760:4,376,733...4,474,834
Ensembl chrNW_004624760:4,376,713...4,474,837 		JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:6271154|PMID:25568335) UniProt PMID:25568335 MGI:6271154 NCBI chrNW_004624750:3,789,015...3,827,079
Ensembl chrNW_004624750:3,789,022...3,827,079 		JBrowse link
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr4a3 nuclear receptor subfamily 4 group A member 3 involved_in ISO (MGI:5586645|PMID:24586680) UniProt PMID:24586680 MGI:5586645 NCBI chrNW_004624825:1,098,915...1,141,373
Ensembl chrNW_004624825:1,097,432...1,141,446 		JBrowse link
positive regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 involved_in ISO (PMID:22328336) UniProt PMID:22328336 NCBI chrNW_004624735:34,337,722...34,516,891
Ensembl chrNW_004624735:34,337,835...34,519,559 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (MGI:4421606|PMID:20080593) UniProt PMID:20080593 MGI:4421606 NCBI chrNW_004624795:1,787,958...1,793,475
Ensembl chrNW_004624795:1,787,958...1,794,692 		JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 acts_upstream_of_or_within ISO (PMID:23502856) MGI PMID:23502856 NCBI chrNW_004624754:25,058,312...25,069,052
Ensembl chrNW_004624754:25,058,204...25,069,561 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 involved_in ISO (MGI:7387171|PMID:23246432)
(PMID:28943315)		 UniProt PMID:23246432 PMID:28943315 MGI:7387171 NCBI chrNW_004624963:142,987...212,190
Ensembl chrNW_004624963:145,580...212,064 		JBrowse link
G Btk Bruton tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624902:1,173,101...1,216,662
Ensembl chrNW_004624902:1,182,682...1,216,171 		JBrowse link
G Casp4 caspase 4 involved_in ISO (MGI:5780643|PMID:26173909) UniProt PMID:26173909 MGI:5780643 NCBI chrNW_004624918:145,661...187,006 JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624739:29,341,620...29,441,232
Ensembl chrNW_004624739:29,407,568...29,441,333 		JBrowse link
G Ddx3x DEAD-box helicase 3 X-linked involved_in ISO (MGI:6368386|PMID:31511697) UniProt PMID:31511697 MGI:6368386 NCBI chrNW_004624762:14,290,267...14,305,437
Ensembl chrNW_004624762:14,290,267...14,305,633 		JBrowse link
G Dhx33 DEAH-box helicase 33 involved_in ISO (PMID:23871209) UniProt PMID:23871209 NCBI chrNW_004624786:9,247,294...9,266,645
Ensembl chrNW_004624786:9,248,382...9,266,519 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:22461501) UniProt PMID:22461501 NCBI chrNW_004624742:8,324,902...8,335,965 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO (MGI:6106673|PMID:28943315)
(PMID:28943315)		 UniProt PMID:28943315 MGI:6106673 NCBI chrNW_004624928:1,442,216...1,494,275
Ensembl chrNW_004624928:1,439,146...1,494,266 		JBrowse link
G Mark4 microtubule affinity regulating kinase 4 involved_in ISO (PMID:28656979)
(MGI:5921465|PMID:28656979)		 UniProt PMID:28656979 MGI:5921465 NCBI chrNW_004624907:2,184,702...2,212,673
Ensembl chrNW_004624907:2,184,729...2,212,666 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:23582325)
(MGI:5492224|PMID:23582325)		 UniProt PMID:23582325 MGI:5492224 NCBI chrNW_004624741:4,936,556...4,951,081
Ensembl chrNW_004624741:4,939,040...4,954,058 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor involved_in ISO (PMID:33718825) UniProt PMID:33718825 NCBI chrNW_004624731:2,677,259...2,681,408
Ensembl chrNW_004624731:2,677,290...2,681,489 		JBrowse link
G Nek7 NIMA related kinase 7 involved_in ISO (MGI:5751332|PMID:26814970)
(PMID:31189953), (PMID:36442502)
(MGI:5698271|PMID:26642356)		 UniProt PMID:26642356 PMID:26814970 PMID:31189953 PMID:36442502 MGI:5698271 MGI:5751332 NCBI chrNW_004624798:2,116,888...2,283,061
Ensembl chrNW_004624798:2,116,900...2,198,999 		JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of_or_within ISO (PMID:32514138) ARUK-UCL PMID:32514138 NCBI chrNW_004624746:5,678,057...5,824,663
Ensembl chrNW_004624746:5,682,666...5,821,855 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624733:38,012,694...38,033,745
Ensembl chrNW_004624733:38,012,392...38,036,914 		JBrowse link
G Prkd1 protein kinase D1 involved_in ISO (MGI:5913002|PMID:28716882) UniProt PMID:28716882 MGI:5913002 NCBI chrNW_004624820:2,408,562...2,726,199
Ensembl chrNW_004624820:2,408,360...2,726,606 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990 		JBrowse link
G Stmp1 short transmembrane mitochondrial protein 1 involved_in ISO (MGI:6384515|PMID:31836654) UniProt PMID:31836654 MGI:6384515 NCBI chrNW_004624765:15,941,281...15,969,027 JBrowse link
G Tlr4 toll like receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (MGI:5546292|PMID:23812099) UniProt PMID:23812099 MGI:5546292 NCBI chrNW_004624840:7,323,022...7,349,334 JBrowse link
G Zdhhc5 zinc finger DHHC-type palmitoyltransferase 5 involved_in ISO (PMID:38092000) UniProt PMID:38092000 NCBI chrNW_004624864:3,027,537...3,049,567
Ensembl chrNW_004624864:3,028,170...3,048,945 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (MGI:6278628|PMID:21277849), (MGI:6450424|PMID:19570976) UniProt PMID:19570976 PMID:21277849 MGI:6278628 MGI:6450424 NCBI chrNW_004624747:26,252,788...26,275,273
Ensembl chrNW_004624747:26,252,492...26,275,173 		JBrowse link
G Slc46a2 solute carrier family 46 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624760:22,124,321...22,134,601
Ensembl chrNW_004624760:22,124,321...22,134,906 		JBrowse link
G Tlr4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nagk N-acetylglucosamine kinase involved_in ISO (MGI:7484284|PMID:36002575)
(PMID:36002575)		 UniProt PMID:36002575 MGI:7484284 NCBI chrNW_004624762:2,382,708...2,391,896
Ensembl chrNW_004624762:2,382,709...2,391,656 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chrNW_004624767:19,920,149...19,938,892
Ensembl chrNW_004624767:19,920,687...19,929,638 		JBrowse link
G Slc15a3 solute carrier family 15 member 3 involved_in ISO (MGI:5571205|PMID:24695226) UniProt PMID:24695226 MGI:5571205 NCBI chrNW_004624926:294,263...303,326
Ensembl chrNW_004624926:294,376...303,248 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (MGI:5571205|PMID:24695226) UniProt PMID:24695226 MGI:5571205 NCBI chrNW_004624747:26,252,788...26,275,273
Ensembl chrNW_004624747:26,252,492...26,275,173 		JBrowse link
G Tlr4 toll like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) Ensembl
MGI		 PMID:18261938 GO_REF:0000107 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
positive regulation of pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zdhhc5 zinc finger DHHC-type palmitoyltransferase 5 involved_in ISO (MGI:6414746|PMID:31649195)
(PMID:31649195)		 UniProt PMID:31649195 MGI:6414746 NCBI chrNW_004624864:3,027,537...3,049,567
Ensembl chrNW_004624864:3,028,170...3,048,945 		JBrowse link
positive regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd17 ankyrin repeat domain 17 involved_in ISO (PMID:22328336) UniProt PMID:22328336 NCBI chrNW_004624735:34,337,722...34,516,891
Ensembl chrNW_004624735:34,337,835...34,519,559 		JBrowse link
G Dhx58 DExH-box helicase 58 involved_in ISO (MGI:4421606|PMID:20080593) UniProt PMID:20080593 MGI:4421606 NCBI chrNW_004624795:1,787,958...1,793,475
Ensembl chrNW_004624795:1,787,958...1,794,692 		JBrowse link
G Pum1 pumilio RNA binding family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:14,361,376...14,486,460
Ensembl chrNW_004624764:14,361,012...14,486,542 		JBrowse link
G Pum2 pumilio RNA binding family member 2 involved_in ISO (PMID:25340845) UniProt PMID:25340845 NCBI chrNW_004624738:2,951,253...3,042,905
Ensembl chrNW_004624738:2,950,415...3,043,011 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 involved_in ISO (PMID:24399297) CACAO PMID:24399297 NCBI chrNW_004624802:5,559,107...5,682,338
Ensembl chrNW_004624802:5,560,574...5,682,300 		JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 involved_in ISO (PMID:21102435) UniProt PMID:21102435 NCBI chrNW_004624765:19,441,299...19,509,468
Ensembl chrNW_004624765:19,439,923...19,509,186 		JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO (PMID:30193849) UniProt PMID:30193849 NCBI chrNW_004624741:1,399,405...1,400,980
Ensembl chrNW_004624741:1,399,481...1,400,701 		JBrowse link
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (PMID:11435465) MGI PMID:11435465 NCBI chrNW_004624790:9,809,550...9,829,199
Ensembl chrNW_004624790:9,809,492...9,829,883 		JBrowse link
G Bcl10 BCL10 immune signaling adaptor involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chrNW_004624742:12,210,333...12,222,533
Ensembl chrNW_004624742:12,210,360...12,221,759 		JBrowse link
G Card11 caspase recruitment domain family member 11 involved_in ISO (MGI:6695669|PMID:12154356)
(PMID:12154360)		 UniProt PMID:12154356 PMID:12154360 MGI:6695669 NCBI chrNW_004624740:29,974,707...30,085,498
Ensembl chrNW_004624740:29,974,689...30,085,981 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:2,777,766...2,787,664
Ensembl chrNW_004624795:2,779,627...2,788,897 		JBrowse link
G Cd226 CD226 molecule involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624806:11,324,239...11,390,487
Ensembl chrNW_004624806:11,324,344...11,388,206 		JBrowse link
G Cd81 CD81 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:15,192,446...15,210,923
Ensembl chrNW_004624767:15,192,452...15,210,922 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO (PMID:16501569) MGI PMID:16501569 NCBI chrNW_004624757:5,895,912...5,953,485 JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (PMID:18287044), (PMID:27777308) UniProt PMID:18287044 PMID:27777308 NCBI chrNW_004624946:997,571...1,015,748
Ensembl chrNW_004624946:996,814...1,013,379 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 involved_in ISO (PMID:18796614) BHF-UCL PMID:18796614 NCBI chrNW_004624907:1,266,348...1,279,258
Ensembl chrNW_004624907:1,266,348...1,278,699 		JBrowse link
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:19179613) MGI PMID:19179613 NCBI chrNW_004624737:49,471...82,981
Ensembl chrNW_004624737:49,371...83,514 		JBrowse link
G LOC101706523 T-cell receptor-associated transmembrane adapter 1 acts_upstream_of_or_within ISO (PMID:11390434) MGI PMID:11390434 NCBI chrNW_004624731:40,281,086...40,319,254
Ensembl chrNW_004624731:40,280,884...40,306,653 		JBrowse link
G LOC101712173 poliovirus receptor homolog involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,582,636...1,596,528 JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,713,786...1,739,158
Ensembl chrNW_004624907:1,713,443...1,740,627 		JBrowse link
G Prkd2 protein kinase D2 involved_in ISO (MGI:4849903|PMID:20819079) UniProt PMID:20819079 MGI:4849903 NCBI chrNW_004624832:6,885,627...6,915,316
Ensembl chrNW_004624832:6,886,327...6,915,179 		JBrowse link
G Rab29 RAB29, member RAS oncogene family involved_in ISO (PMID:26021297) ParkinsonsUK-UCL PMID:26021297 NCBI chrNW_004624807:5,478,570...5,483,473
Ensembl chrNW_004624807:5,478,707...5,483,475 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:20,732,813...20,742,016
Ensembl chrNW_004624767:20,732,938...20,741,272 		JBrowse link
G Rps3 ribosomal protein S3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624817:1,710,768...1,715,923
Ensembl chrNW_004624817:1,710,768...1,716,224 		JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624983:31,552...47,575
Ensembl chrNW_004624983:31,766...45,077 		JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 involved_in ISO (PMID:38225265) UniProt PMID:38225265 NCBI chrNW_004624754:16,701,950...16,798,293
Ensembl chrNW_004624754:16,701,331...16,798,897 		JBrowse link
positive regulation of toll-like receptor 13 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Treml4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (MGI:5775261|PMID:25848864) UniProt PMID:25848864 MGI:5775261 NCBI chrNW_004624754:17,600,341...17,608,766 JBrowse link
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) UniProt PMID:19865078 NCBI chrNW_004624869:1,326,605...1,337,195 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (MGI:5788395|PMID:16267105) UniProt PMID:16267105 MGI:5788395 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184 		JBrowse link
G LOC101717043 cytochrome b-245 light chain involved_in ISO (PMID:22423966) UniProt PMID:22423966 NCBI chrNW_004624746:911,852...919,361
Ensembl chrNW_004624746:911,842...919,362 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (MGI:6162316|PMID:26599367)
(PMID:26599367), (PMID:28471450)		 UniProt PMID:26599367 PMID:28471450 MGI:6162316 NCBI chrNW_004624839:4,908,861...5,000,218
Ensembl chrNW_004624839:4,908,639...5,000,677 		JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624743:27,251,937...27,331,213
Ensembl chrNW_004624743:27,254,436...27,301,934 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) BHF-UCL PMID:19509286 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646 		JBrowse link
G Tlr1 toll like receptor 1 involved_in ISO (PMID:22198949) ARUK-UCL PMID:22198949 NCBI chrNW_004624840:7,287,772...7,349,282
Ensembl chrNW_004624840:7,287,781...7,290,162 		JBrowse link
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004624827:2,844,855...2,878,367
Ensembl chrNW_004624827:2,844,115...2,879,179 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) UniProt PMID:19865078 NCBI chrNW_004624869:1,326,605...1,337,195 JBrowse link
G Flot1 flotillin 1 involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004624754:24,992,961...25,000,463
Ensembl chrNW_004624754:24,992,929...25,003,759 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chrNW_004624762:9,328,275...9,382,996
Ensembl chrNW_004624762:9,328,109...9,386,067 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (MGI:4943396|PMID:17322885) BHF-UCL PMID:17322885 MGI:4943396 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646 		JBrowse link
G Trim3 tripartite motif containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624817:7,965,976...7,991,426
Ensembl chrNW_004624817:7,965,976...7,991,411 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624823:1,353,601...1,405,762
Ensembl chrNW_004624823:1,353,621...1,401,160 		JBrowse link
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (MGI:5645195|PMID:24380872) UniProt PMID:24380872 MGI:5645195 NCBI chrNW_004624743:33,372,023...33,374,438
Ensembl chrNW_004624743:33,367,898...33,373,922 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:18622013) UniProt PMID:18622013 NCBI chrNW_004624869:1,326,605...1,337,195 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (MGI:5788395|PMID:16267105) UniProt PMID:16267105 MGI:5788395 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184 		JBrowse link
G Ifi35 interferon induced protein 35 involved_in ISO (PMID:29038465) UniProt PMID:29038465 NCBI chrNW_004624795:1,260,476...1,268,015
Ensembl chrNW_004624795:1,260,476...1,262,080 		JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO (PMID:11528597) BHF-UCL PMID:11528597 NCBI chrNW_004624842:1,306,299...1,332,269
Ensembl chrNW_004624842:1,301,831...1,332,346 		JBrowse link
G LOC101722352 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:22685567)
(PMID:19412184)		 UniProt PMID:19412184 PMID:22685567 NCBI chrNW_004624733:6,304,454...6,341,827 JBrowse link
G Ltf lactotransferrin involved_in ISO (PMID:20345905) UniProt PMID:20345905 NCBI chrNW_004624730:74,636,554...74,656,817
Ensembl chrNW_004624730:74,636,522...74,656,886 		JBrowse link
G Ninj1 ninjurin 1 involved_in ISO (MGI:6694429|PMID:25860173) UniProt PMID:25860173 MGI:6694429 NCBI chrNW_004624868:3,430,539...3,442,205
Ensembl chrNW_004624868:3,430,209...3,445,542 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 involved_in ISO (PMID:18511497) BHF-UCL PMID:18511497 NCBI chrNW_004624767:1,459,601...1,473,224
Ensembl chrNW_004624767:1,459,601...1,467,795 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chrNW_004624762:9,328,275...9,382,996
Ensembl chrNW_004624762:9,328,109...9,386,067 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:19509286) BHF-UCL PMID:19509286 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646 		JBrowse link
G Wdfy1 WD repeat and FYVE domain containing 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624823:1,353,601...1,405,762
Ensembl chrNW_004624823:1,353,621...1,401,160 		JBrowse link
G Znrf1 zinc and ring finger 1 involved_in ISO (PMID:28593998) UniProt PMID:28593998 NCBI chrNW_004624746:11,847,627...11,954,637
Ensembl chrNW_004624746:11,848,425...11,954,784 		JBrowse link
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3 X-linked involved_in ISO (PMID:30341167) UniProt PMID:30341167 NCBI chrNW_004624762:14,290,267...14,305,437
Ensembl chrNW_004624762:14,290,267...14,305,633 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624846:3,395,536...3,408,616
Ensembl chrNW_004624846:3,395,406...3,408,626 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:25238095), (PMID:32433612)
(MGI:4848237|PMID:21045126), (MGI:6357091|PMID:25238095)		 UniProt PMID:21045126 PMID:25238095 PMID:32433612 MGI:4848237 MGI:6357091 NCBI chrNW_004624747:26,252,788...26,275,273
Ensembl chrNW_004624747:26,252,492...26,275,173 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624762:25,427,519...25,448,180
Ensembl chrNW_004624762:25,430,926...25,448,114 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells like 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624754:17,600,341...17,608,766 JBrowse link
positive regulation of toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3 X-linked involved_in ISO (PMID:30341167) UniProt PMID:30341167 NCBI chrNW_004624762:14,290,267...14,305,437
Ensembl chrNW_004624762:14,290,267...14,305,633 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (PMID:32433612) UniProt PMID:32433612 NCBI chrNW_004624747:26,252,788...26,275,273
Ensembl chrNW_004624747:26,252,492...26,275,173 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624762:25,427,519...25,448,180
Ensembl chrNW_004624762:25,430,926...25,448,114 		JBrowse link
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624846:3,395,536...3,408,616
Ensembl chrNW_004624846:3,395,406...3,408,626 		JBrowse link
G Rtn4 reticulon 4 involved_in ISO (MGI:6274965|PMID:25917084) UniProt PMID:25917084 MGI:6274965 NCBI chrNW_004624833:6,514,409...6,584,061 JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (MGI:4848237|PMID:21045126), (MGI:6278628|PMID:21277849), (MGI:6357091|PMID:25238095)
(PMID:25238095)		 UniProt PMID:21045126 PMID:21277849 PMID:25238095 MGI:4848237 MGI:6278628 MGI:6357091 NCBI chrNW_004624747:26,252,788...26,275,273
Ensembl chrNW_004624747:26,252,492...26,275,173 		JBrowse link
G Treml4 triggering receptor expressed on myeloid cells like 4 involved_in ISO (MGI:5775261|PMID:25848864) UniProt PMID:25848864 MGI:5775261 NCBI chrNW_004624754:17,600,341...17,608,766 JBrowse link
G Zdhhc3 zinc finger DHHC-type palmitoyltransferase 3 involved_in ISO (PMID:38169466) UniProt PMID:38169466 NCBI chrNW_004624730:75,561,842...75,597,867
Ensembl chrNW_004624730:75,561,812...75,599,152 		JBrowse link
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gdi1 GDP dissociation inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624946:902,831...908,815
Ensembl chrNW_004624946:902,461...909,613 		JBrowse link
G Lrch4 leucine rich repeats and calponin homology domain containing 4 involved_in ISO (MGI:3615854|PMID:16449650) UniProt PMID:16449650 MGI:3615854 NCBI chrNW_004624740:16,491,804...16,503,682
Ensembl chrNW_004624740:16,491,837...16,503,491 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (MGI:5487531|PMID:20728433) UniProt PMID:20728433 MGI:5487531 NCBI chrNW_004624737:8,021,478...8,154,543
Ensembl chrNW_004624737:8,022,836...8,154,422 		JBrowse link
regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd19 CD19 molecule involved_in ISO (MGI:1100180|PMID:9382888)
(PMID:9382888)		 UniProt PMID:9382888 MGI:1100180 NCBI chrNW_004624782:12,844,148...12,850,770
Ensembl chrNW_004624782:12,845,432...12,850,576 		JBrowse link
G Fcmr Fc mu receptor involved_in ISO (MGI:5888941|PMID:28135254) UniProt PMID:28135254 MGI:5888941 NCBI chrNW_004624807:4,567,240...4,581,406 JBrowse link
G Gcsam germinal center associated signaling and motility involved_in ISO (PMID:23299888) UniProt PMID:23299888 NCBI chrNW_004624731:36,444,290...36,451,195 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902 		JBrowse link
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csk C-terminal Src kinase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:9325302 GO_REF:0000118 RGD:2303720 NCBI chrNW_004624894:12,621...29,400
Ensembl chrNW_004624894:24,203...29,668 		JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa ISO RGD PMID:16482158 PMID:22184119 RGD:11041001 RGD:2293335 NCBI chrNW_004624826:23,930...34,735 JBrowse link
G Pten phosphatase and tensin homolog ISO negative regulation RGD PMID:18056380 RGD:2292524 NCBI chrNW_004624791:13,975,235...14,056,900 JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:15235600)
(PMID:17341663)		 MGI PMID:15235600 PMID:17341663 NCBI chrNW_004624740:8,624,231...8,688,747
Ensembl chrNW_004624740:8,624,205...8,690,800 		JBrowse link
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf1 interferon regulatory factor 1 involved_in ISO (MGI:3691368|PMID:17018642) UniProt PMID:17018642 MGI:3691368 NCBI chrNW_004624733:39,596,565...39,603,428
Ensembl chrNW_004624733:39,596,501...39,603,526 		JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (MGI:3575992|PMID:15800576) UniProt PMID:15800576 MGI:3575992 NCBI chrNW_004624766:21,850,211...21,853,189 JBrowse link
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf7 interferon regulatory factor 7 involved_in ISO (MGI:3575992|PMID:15800576) UniProt PMID:15800576 MGI:3575992 NCBI chrNW_004624766:21,850,211...21,853,189 JBrowse link
regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak2 eukaryotic translation initiation factor 2 alpha kinase 2 involved_in ISO (MGI:5432942|PMID:22801494) UniProt PMID:22801494 MGI:5432942 NCBI chrNW_004624738:18,716,623...18,764,243
Ensembl chrNW_004624738:18,717,092...18,758,457 		JBrowse link
regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a2 solute carrier family 15 member 2 involved_in ISO (MGI:6192142|PMID:29784761) UniProt PMID:29784761 MGI:6192142 NCBI chrNW_004624912:180,048...222,909
Ensembl chrNW_004624912:179,969...222,909 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISO (MGI:6192142|PMID:29784761) UniProt PMID:29784761 MGI:6192142 NCBI chrNW_004624747:26,252,788...26,275,273
Ensembl chrNW_004624747:26,252,492...26,275,173 		JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) MGI PMID:23892723 NCBI chrNW_004624767:19,920,149...19,938,892
Ensembl chrNW_004624767:19,920,687...19,929,638 		JBrowse link
regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:27824081) UniProt PMID:27824081 NCBI chrNW_004624832:6,144,260...6,154,172
Ensembl chrNW_004624832:6,145,749...6,154,411 		JBrowse link
regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl10 BCL10 immune signaling adaptor acts_upstream_of_or_within ISO (PMID:14614861) MGI PMID:14614861 NCBI chrNW_004624742:12,210,333...12,222,533
Ensembl chrNW_004624742:12,210,360...12,221,759 		JBrowse link
G Cd300a CD300a molecule involved_in ISO (PMID:22046970) UniProt PMID:22046970 NCBI chrNW_004624801:4,404,376...4,420,836
Ensembl chrNW_004624801:4,404,262...4,421,097 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:14752163) MGI PMID:14752163 NCBI chrNW_004624764:15,469,582...15,495,351
Ensembl chrNW_004624764:15,472,685...15,495,351 		JBrowse link
G Malt1 MALT1 paracaspase acts_upstream_of_or_within ISO (PMID:14614861) MGI PMID:14614861 NCBI chrNW_004624792:4,148,258...4,223,431
Ensembl chrNW_004624792:4,148,453...4,217,548 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:3580753|PMID:15917799) BHF-UCL PMID:15917799 MGI:3580753 NCBI chrNW_004624771:7,837,547...7,948,217 JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:28598420) MGI
Ensembl		 PMID:28598420 GO_REF:0000107 NCBI chrNW_004624983:31,552...47,575
Ensembl chrNW_004624983:31,766...45,077 		JBrowse link
regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flot2 flotillin 2 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004624786:1,449,001...1,465,208
Ensembl chrNW_004624786:1,450,234...1,465,102 		JBrowse link
G Hcfc2 host cell factor C2 acts_upstream_of_or_within ISO (PMID:28970238) MGI PMID:28970238 NCBI chrNW_004624750:4,627,848...4,660,448
Ensembl chrNW_004624750:4,629,669...4,660,413 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:37158982) UniProt PMID:37158982 NCBI chrNW_004624842:2,212,561...2,260,514
Ensembl chrNW_004624842:2,211,020...2,230,132 		JBrowse link
regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (MGI:6270783|PMID:27219021) UniProt PMID:27219021 MGI:6270783 NCBI chrNW_004624822:31,175...74,252
Ensembl chrNW_004624822:33,880...74,308 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:6270783|PMID:27219021) UniProt PMID:27219021 MGI:6270783 NCBI chrNW_004624750:3,789,015...3,827,079
Ensembl chrNW_004624750:3,789,022...3,827,079 		JBrowse link
G Flot1 flotillin 1 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004624754:24,992,961...25,000,463
Ensembl chrNW_004624754:24,992,929...25,003,759 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624815:1,290,106...1,376,961
Ensembl chrNW_004624815:1,289,997...1,369,610 		JBrowse link
regulation of toll-like receptor 6 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6695864|PMID:31134514) ARUK-UCL PMID:31134514 MGI:6695864 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231 		JBrowse link
regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO (PMID:20037584) ARUK-UCL PMID:20037584 NCBI chrNW_004624745:13,904,912...14,159,374
Ensembl chrNW_004624745:13,902,577...14,159,372 		JBrowse link
G Cd36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624739:29,341,620...29,441,232
Ensembl chrNW_004624739:29,407,568...29,441,333 		JBrowse link
G Esr1 estrogen receptor 1 acts_upstream_of_or_within ISO (PMID:22659029) MGI PMID:22659029 NCBI chrNW_004624785:6,164,507...6,601,302
Ensembl chrNW_004624785:6,164,379...6,601,326 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624742:5,260,651...5,271,908
Ensembl chrNW_004624742:5,261,537...5,270,695 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (MGI:6158883|PMID:20616063) UniProt PMID:20616063 MGI:6158883 NCBI chrNW_004624839:4,908,861...5,000,218
Ensembl chrNW_004624839:4,908,639...5,000,677 		JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624762:25,427,519...25,448,180
Ensembl chrNW_004624762:25,430,926...25,448,114 		JBrowse link
RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clpb ClpB family mitochondrial disaggregase involved_in ISO (PMID:31522117) UniProt PMID:31522117 NCBI chrNW_004624817:4,593,823...4,735,573
Ensembl chrNW_004624817:4,593,639...4,735,091 		JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor acts_upstream_of_or_within ISO (PMID:22745163) MGI PMID:22745163 NCBI chrNW_004624794:8,913,278...9,035,652 JBrowse link
G Mavs mitochondrial antiviral signaling protein acts_upstream_of_or_within ISO (PMID:22745163) MGI PMID:22745163 NCBI chrNW_004624741:4,936,556...4,951,081
Ensembl chrNW_004624741:4,939,040...4,954,058 		JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:31522117) UniProt PMID:31522117 NCBI chrNW_004624795:5,556,728...5,565,969
Ensembl chrNW_004624795:5,556,450...5,565,988 		JBrowse link
G Phb2 prohibitin 2 involved_in ISO (PMID:31522117) UniProt PMID:31522117 NCBI chrNW_004624860:3,599,435...3,605,016
Ensembl chrNW_004624860:3,599,687...3,604,872 		JBrowse link
G Rigi RNA sensor RIG-I involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624736:37,134,718...37,204,543
Ensembl chrNW_004624736:37,133,059...37,197,218 		JBrowse link
G Rnf135 ring finger protein 135 involved_in ISO (MGI:6152590|PMID:21147464), (MGI:6377978|PMID:28469175)
(PMID:23950712)
(PMID:28469175), (PMID:31006531)		 UniProt PMID:21147464 PMID:23950712 PMID:28469175 PMID:31006531 MGI:6152590 MGI:6377978 NCBI chrNW_004624875:221,206...231,178
Ensembl chrNW_004624875:220,771...232,394 		JBrowse link
G Trim25 tripartite motif containing 25 NOT|involved_in ISO (PMID:31006531) UniProt PMID:31006531 NCBI chrNW_004624795:11,967,908...11,986,707
Ensembl chrNW_004624795:11,971,610...11,986,608 		JBrowse link
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clec7a C-type lectin domain containing 7A involved_in ISO (MGI:3844414|PMID:19136564) ARUK-UCL PMID:19136564 MGI:3844414 NCBI chrNW_004624752:26,871,556...26,885,778
Ensembl chrNW_004624752:26,871,292...26,891,910 		JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (MGI:3844414|PMID:19136564), (MGI:5300086|PMID:22041900) ARUK-UCL PMID:19136564 PMID:22041900 MGI:3844414 MGI:5300086 NCBI chrNW_004624746:5,678,057...5,824,663
Ensembl chrNW_004624746:5,682,666...5,821,855 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chrNW_004624794:10,183,934...10,187,180
Ensembl chrNW_004624794:10,183,515...10,187,244 		JBrowse link
stimulatory killer cell immunoglobulin-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tyrobp transmembrane immune signaling adaptor TYROBP involved_in ISO (PMID:9655483) UniProt PMID:9655483 NCBI chrNW_004624794:10,183,934...10,187,180
Ensembl chrNW_004624794:10,183,515...10,187,244 		JBrowse link
T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18305217) MGI PMID:18305217 NCBI chrNW_004624760:4,878,811...5,032,719
Ensembl chrNW_004624760:4,878,556...5,031,491 		JBrowse link
G Ada adenosine deaminase acts_upstream_of ISO (PMID:11435465) MGI PMID:11435465 NCBI chrNW_004624790:9,809,550...9,829,199
Ensembl chrNW_004624790:9,809,492...9,829,883 		JBrowse link
G Bcl10 BCL10 immune signaling adaptor involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004624742:12,210,333...12,222,533
Ensembl chrNW_004624742:12,210,360...12,221,759 		JBrowse link
G Bmx BMX non-receptor tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624829:297,187...344,555
Ensembl chrNW_004624829:297,351...344,164 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:18228248) MGI PMID:18228248 NCBI chrNW_004624765:20,766,368...20,951,560
Ensembl chrNW_004624765:20,773,885...20,951,736 		JBrowse link
G Btk Bruton tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624902:1,173,101...1,216,662
Ensembl chrNW_004624902:1,182,682...1,216,171 		JBrowse link
G Btn1a1 butyrophilin subfamily 1 member A1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624756:356,124...362,425
Ensembl chrNW_004624756:357,047...362,415 		JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 acts_upstream_of_or_within ISO (PMID:17028169) MGI PMID:17028169 NCBI chrNW_004624816:3,334,934...3,348,355
Ensembl chrNW_004624816:3,334,684...3,347,842 		JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within ISO (PMID:15637280), (PMID:17028169) MGI PMID:15637280 PMID:17028169 NCBI chrNW_004624866:4,973,087...5,287,477
Ensembl chrNW_004624866:4,973,207...5,281,746 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (PMID:23793062) MGI PMID:23793062 NCBI chrNW_004624746:18,692,179...18,704,952
Ensembl chrNW_004624746:18,692,225...18,704,476 		JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO (PMID:12697763) MGI PMID:12697763 NCBI chrNW_004624731:43,803,743...44,018,682
Ensembl chrNW_004624731:43,803,768...44,015,870 		JBrowse link
G Cd247 CD247 molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11435465) MGI
TreeGrafter		 PMID:11435465 GO_REF:0000118 NCBI chrNW_004624826:5,504,676...5,574,037
Ensembl chrNW_004624826:5,505,569...5,573,783 		JBrowse link
G Cd276 CD276 molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624781:691,348...703,202 JBrowse link
G Cd28 CD28 molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23793062) TreeGrafter
MGI		 PMID:23793062 GO_REF:0000118 NCBI chrNW_004624765:12,650,092...12,667,168 JBrowse link
G Cd2ap CD2 associated protein acts_upstream_of_or_within ISO (PMID:14512504) MGI PMID:14512504 NCBI chrNW_004624754:13,420,594...13,511,672
Ensembl chrNW_004624754:13,420,603...13,511,523 		JBrowse link
G Cd3e CD3e molecule acts_upstream_of_or_within ISO (PMID:10485657) MGI PMID:10485657 NCBI chrNW_004624784:13,714,667...13,726,881
Ensembl chrNW_004624784:13,712,920...13,726,950 		JBrowse link
G Cd8a CD8 subunit alpha involved_in ISO (PMID:17145893) ComplexPortal PMID:17145893 NCBI chrNW_004624749:16,564,944...16,569,890 JBrowse link
G Cd8b CD8 subunit beta involved_in ISO (PMID:17145893) ComplexPortal PMID:17145893 NCBI chrNW_004624749:16,513,360...16,525,494 JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO (PMID:18305217) MGI PMID:18305217 NCBI chrNW_004624945:734,532...767,184
Ensembl chrNW_004624945:734,532...767,168 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte associated protein 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624765:12,449,205...12,454,324
Ensembl chrNW_004624765:12,449,205...12,454,324 		JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822)
(MGI:5751612|PMID:26774822)		 UniProt PMID:26774822 MGI:5751612 NCBI chrNW_004624798:2,621,604...2,844,370
Ensembl chrNW_004624798:2,622,379...2,838,775 		JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004624747:23,413,045...23,422,227
Ensembl chrNW_004624747:23,414,077...23,421,074 		JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624734:26,682,521...26,688,490
Ensembl chrNW_004624734:26,682,521...26,688,559 		JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004624906:733,148...882,690
Ensembl chrNW_004624906:733,146...892,362 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004624738:9,438,484...9,443,931
Ensembl chrNW_004624738:9,437,554...9,443,747 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon involved_in ISO (PMID:8626696) UniProt PMID:8626696 NCBI chrNW_004624730:72,417,069...72,428,194
Ensembl chrNW_004624730:72,417,856...72,428,093 		JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 involved_in ISO (PMID:32098969) UniProt PMID:32098969 NCBI chrNW_004624908:1,327,569...1,340,741
Ensembl chrNW_004624908:1,327,602...1,340,240 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:32610127) MGI PMID:32610127 NCBI chrNW_004624738:10,370,479...10,391,623
Ensembl chrNW_004624738:10,370,103...10,391,623 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO (PMID:10072494), (PMID:11265635) MGI PMID:10072494 PMID:11265635 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679 		JBrowse link
G Fyb1 FYN binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624759:15,683,741...15,794,628
Ensembl chrNW_004624759:15,683,779...15,793,908 		JBrowse link
G Fyb2 FYN binding protein 2 involved_in ISO (PMID:27335501) UniProt PMID:27335501 NCBI chrNW_004624862:3,323,643...3,463,825 JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624933:248,298...456,933
Ensembl chrNW_004624933:389,627...456,520 		JBrowse link
G Gata3 GATA binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624775:2,985,077...3,014,567
Ensembl chrNW_004624775:2,994,164...3,015,392 		JBrowse link
G Hras HRas proto-oncogene, GTPase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21444916) MGI
Ensembl		 PMID:21444916 GO_REF:0000107 NCBI chrNW_004624766:21,907,423...21,913,414
Ensembl chrNW_004624766:21,911,241...21,913,653 		JBrowse link
G Icoslg inducible T cell costimulator ligand involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624745:29,880,943...29,888,635
Ensembl chrNW_004624745:29,880,992...29,888,717 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534 		JBrowse link
G Itk IL2 inducible T cell kinase involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624733:32,125,005...32,198,901
Ensembl chrNW_004624733:32,127,388...32,198,869 		JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:15,244,521...15,292,901
Ensembl chrNW_004624764:15,244,390...15,275,379 		JBrowse link
G Lat linker for activation of T cells involved_in ISO (PMID:25907557) UniProt PMID:25907557 NCBI chrNW_004624782:12,795,104...12,799,496
Ensembl chrNW_004624782:12,795,104...12,799,410 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:8943371) UniProt PMID:8943371 NCBI chrNW_004624764:15,469,582...15,495,351
Ensembl chrNW_004624764:15,472,685...15,495,351 		JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 involved_in ISO (PMID:20551903) UniProt PMID:20551903 NCBI chrNW_004624733:19,625,276...19,720,125
Ensembl chrNW_004624733:19,672,868...19,719,584 		JBrowse link
G LOC101697345 HLA class II histocompatibility antigen, DP beta 1 chain involved_in ISO (PMID:32341563) UniProt PMID:32341563 NCBI chrNW_004624754:23,661,031...23,672,549
Ensembl chrNW_004624754:23,658,339...23,672,663 		JBrowse link
G LOC101698274 V-set domain-containing T-cell activation inhibitor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624731:27,867,562...27,900,768 JBrowse link
G LOC101703821 HLA class II histocompatibility antigen, DQ beta 1 chain involved_in ISO (PMID:32341563) UniProt PMID:32341563 NCBI chrNW_004624754:23,895,509...23,902,487
Ensembl chrNW_004624754:23,895,607...23,906,713 		JBrowse link
G LOC101716577 tyrosine-protein kinase ZAP-70 involved_in
acts_upstream_of_or_within		 ISO (PMID:9489702)
(PMID:9208839)		 UniProt
MGI		 PMID:9208839 PMID:9489702 NCBI chrNW_004624749:2,893,601...2,901,256
Ensembl chrNW_004624749:2,893,601...2,901,035 		JBrowse link
G LOC106008672 butyrophilin-like protein 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624958:519,966...591,348 JBrowse link
G Malt1 MALT1 paracaspase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624792:4,148,258...4,223,431
Ensembl chrNW_004624792:4,148,453...4,217,548 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 acts_upstream_of_or_within ISO (PMID:9064344) MGI PMID:9064344 NCBI chrNW_004624747:1,296,062...1,389,674
Ensembl chrNW_004624747:1,296,221...1,389,757 		JBrowse link
G Mog myelin oligodendrocyte glycoprotein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624754:25,397,191...25,412,123
Ensembl chrNW_004624754:25,397,144...25,411,319 		JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004624794:10,172,789...10,180,693
Ensembl chrNW_004624794:10,168,792...10,179,510 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004624789:15,612,311...15,623,878
Ensembl chrNW_004624789:15,612,335...15,624,152 		JBrowse link
G Nras NRAS proto-oncogene, GTPase acts_upstream_of_or_within ISO (PMID:21444916) MGI PMID:21444916 NCBI chrNW_004624772:10,358,554...10,369,371 JBrowse link
G Pde4b phosphodiesterase 4B involved_in ISO (PMID:17404263) BHF-UCL PMID:17404263 NCBI chrNW_004624742:28,557,159...29,113,269
Ensembl chrNW_004624742:28,557,283...29,016,844 		JBrowse link
G Plcg1 phospholipase C gamma 1 acts_upstream_of_or_within ISO (PMID:15728238) MGI PMID:15728238 NCBI chrNW_004624919:1,766,533...1,800,130
Ensembl chrNW_004624919:1,766,149...1,803,097 		JBrowse link
G Plcg2 phospholipase C gamma 2 acts_upstream_of_or_within ISO (PMID:15728238) MGI PMID:15728238 NCBI chrNW_004624746:5,678,057...5,824,663
Ensembl chrNW_004624746:5,682,666...5,821,855 		JBrowse link
G Pram1 PML-RARA regulated adaptor molecule 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624828:1,251,566...1,259,032
Ensembl chrNW_004624828:1,251,815...1,256,314 		JBrowse link
G Prkd2 protein kinase D2 involved_in ISO (PMID:17077180) BHF-UCL PMID:17077180 NCBI chrNW_004624832:6,885,627...6,915,316
Ensembl chrNW_004624832:6,886,327...6,915,179 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO (PMID:17698590) MGI PMID:17698590 NCBI chrNW_004624734:28,200,358...28,272,684
Ensembl chrNW_004624734:28,200,140...28,272,743 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (PMID:17698590) MGI PMID:17698590 NCBI chrNW_004624771:17,183,538...17,205,460
Ensembl chrNW_004624771:17,183,447...17,224,188 		JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14752163) MGI
Ensembl
TreeGrafter		 PMID:14752163 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624772:9,472,869...9,552,751
Ensembl chrNW_004624772:9,472,913...9,550,990 		JBrowse link
G Ptpn6 protein tyrosine phosphatase non-receptor type 6 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:9064344) Ensembl
MGI		 PMID:9064344 GO_REF:0000107 NCBI chrNW_004624860:3,580,225...3,595,403
Ensembl chrNW_004624860:3,580,560...3,595,090 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 involved_in ISO (PMID:20005846) UniProt PMID:20005846 NCBI chrNW_004624741:1,503,017...1,523,542
Ensembl chrNW_004624741:1,502,942...1,523,675 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (MGI:6142401|PMID:25282160) UniProt PMID:25282160 MGI:6142401 NCBI chrNW_004624771:7,837,547...7,948,217 JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624760:12,025,206...12,074,548 JBrowse link
G Rftn1 raftlin, lipid raft linker 1 involved_in ISO (MGI:3850290|PMID:19414744) UniProt PMID:19414744 MGI:3850290 NCBI chrNW_004624821:1,561,845...1,763,654
Ensembl chrNW_004624821:1,562,778...1,751,345 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 ISO (MGI:5285496|PMID:21469090)
(PMID:11894098)		 UniProt
MGI		 PMID:11894098 PMID:21469090 MGI:5285496 NCBI chrNW_004624744:2,194,339...2,227,498
Ensembl chrNW_004624744:2,201,319...2,226,890 		JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO (PMID:20005846) UniProt PMID:20005846 NCBI chrNW_004624820:8,376,530...8,388,596
Ensembl chrNW_004624820:8,375,871...8,388,569 		JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO (PMID:24645804) MGI PMID:24645804 NCBI chrNW_004624825:3,846,604...3,972,780
Ensembl chrNW_004624825:3,845,092...3,973,636 		JBrowse link
G Skap1 src kinase associated phosphoprotein 1 involved_in ISO (PMID:11909961) UniProt PMID:11909961 NCBI chrNW_004624795:4,726,715...4,960,167
Ensembl chrNW_004624795:4,727,149...4,960,082 		JBrowse link
G Slc39a6 solute carrier family 39 member 6 involved_in ISO (PMID:34394081) UniProt PMID:34394081 NCBI chrNW_004624779:10,400,581...10,433,405
Ensembl chrNW_004624779:10,399,198...10,432,869 		JBrowse link
G Spn sialophorin involved_in ISO PMID:12496963 ARUK-UCL PMID:12496963 RGD:1358565 NCBI chrNW_004624782:13,471,083...13,483,712 JBrowse link
G Sppl3 signal peptide peptidase like 3 involved_in ISO (PMID:25384971)
(MGI:5640905|PMID:25384971)		 UniProt PMID:25384971 MGI:5640905 NCBI chrNW_004624747:12,795,803...12,925,319
Ensembl chrNW_004624747:12,795,563...12,928,649 		JBrowse link
G Stk11 serine/threonine kinase 11 acts_upstream_of_or_within ISO (PMID:21487392) MGI PMID:21487392 NCBI chrNW_004624828:7,444,339...7,466,926
Ensembl chrNW_004624828:7,445,069...7,467,298 		JBrowse link
G Stoml2 stomatin like 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18641330) UniProt
Ensembl		 PMID:18641330 GO_REF:0000107 NCBI chrNW_004624915:294,781...298,312
Ensembl chrNW_004624915:294,777...298,278 		JBrowse link
G Tec tec protein tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624761:18,695,168...18,824,045
Ensembl chrNW_004624761:18,695,177...18,822,078 		JBrowse link
G Themis thymocyte selection associated involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624753:2,214,779...2,292,936 JBrowse link
G Themis2 thymocyte selection associated family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22732588) TreeGrafter
MGI		 PMID:22732588 GO_REF:0000118 NCBI chrNW_004624764:11,717,083...11,732,791
Ensembl chrNW_004624764:11,717,950...11,732,799 		JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624784:14,779,533...14,784,315
Ensembl chrNW_004624784:14,780,698...14,784,897 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISO (MGI:2137821|PMID:11485735) UniProt PMID:11485735 MGI:2137821 NCBI chrNW_004624754:13,567,898...13,633,368
Ensembl chrNW_004624754:13,567,734...13,634,009 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:23514740)
(PMID:15125833)		 UniProt PMID:15125833 PMID:23514740 NCBI chrNW_004624767:10,729,766...10,803,253
Ensembl chrNW_004624767:10,729,413...10,748,455 		JBrowse link
G Txk TXK tyrosine kinase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624761:18,841,795...18,897,564
Ensembl chrNW_004624761:18,841,795...18,897,458 		JBrowse link
G Ube2n ubiquitin conjugating enzyme E2 N involved_in ISO (PMID:15125833) UniProt PMID:15125833 NCBI chrNW_004624750:13,432,657...13,468,797
Ensembl chrNW_004624750:13,432,661...13,457,776 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624772:12,837,940...12,911,263
Ensembl chrNW_004624772:12,837,668...12,911,802 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in ISO (MGI:6141968|PMID:27400149) BHF-UCL PMID:27400149 MGI:6141968 NCBI chrNW_004624735:8,987,390...9,122,277
Ensembl chrNW_004624735:8,987,469...9,124,516 		JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:20,224,919...20,234,108
Ensembl chrNW_004624764:20,224,906...20,234,629 		JBrowse link
G Znf683 zinc finger protein 683 involved_in ISO (PMID:26179882) UniProt PMID:26179882 NCBI chrNW_004624764:10,382,733...10,388,608 JBrowse link
TIRAP-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:11544529) BHF-UCL PMID:11544529 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646 		JBrowse link
toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184 		JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:10383454)
(PMID:10549626)		 BHF-UCL
MGI		 PMID:10383454 PMID:10549626 NCBI chrNW_004624946:613,392...618,459
Ensembl chrNW_004624946:613,890...618,445 		JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chrNW_004624786:478,048...491,086 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 acts_upstream_of ISO (PMID:15220916) MGI PMID:15220916 NCBI chrNW_004624757:5,956,873...6,000,052
Ensembl chrNW_004624757:5,958,486...6,000,103 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:8,021,478...8,154,543
Ensembl chrNW_004624737:8,022,836...8,154,422 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894098) MGI PMID:11894098 NCBI chrNW_004624744:2,194,339...2,227,498
Ensembl chrNW_004624744:2,201,319...2,226,890 		JBrowse link
G Tlr2 toll like receptor 2 involved_in ISO (PMID:17128265) BHF-UCL PMID:17128265 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (MGI:3656197|PMID:16633345) UniProt PMID:16633345 MGI:3656197 NCBI chrNW_004624755:24,976,375...24,995,150
Ensembl chrNW_004624755:24,976,361...25,001,397 		JBrowse link
toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule involved_in ISO (MGI:5645190|PMID:25158758) UniProt PMID:25158758 MGI:5645190 NCBI chrNW_004624912:350,201...432,410
Ensembl chrNW_004624912:350,157...426,712 		JBrowse link
G Colec12 collectin subfamily member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624770:10,860,097...11,136,478
Ensembl chrNW_004624770:10,859,205...11,013,175 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) UniProt PMID:22842346 MGI:5437532 NCBI chrNW_004624733:32,521,318...32,527,499 JBrowse link
G Lgals9 galectin 9 involved_in ISO PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chrNW_004624786:478,048...491,086 JBrowse link
G Oas1 2'-5'-oligoadenylate synthetase 1 involved_in ISO (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chrNW_004624747:19,428,994...19,434,512
Ensembl chrNW_004624747:19,428,833...19,434,550 		JBrowse link
G Rftn1 raftlin, lipid raft linker 1 acts_upstream_of_or_within ISO (PMID:21266579) MGI PMID:21266579 NCBI chrNW_004624821:1,561,845...1,763,654
Ensembl chrNW_004624821:1,562,778...1,751,345 		JBrowse link
G Scara3 scavenger receptor class A member 3 NOT|involved_in ISO (PMID:25204797) UniProt PMID:25204797 NCBI chrNW_004624758:22,454,181...22,488,431
Ensembl chrNW_004624758:22,454,213...22,488,452 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:8,975,216...8,982,825
Ensembl chrNW_004624786:8,974,587...9,007,986 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (PMID:12471095) UniProt PMID:12471095 NCBI chrNW_004624828:4,964,199...4,973,465
Ensembl chrNW_004624828:4,971,093...4,973,198 		JBrowse link
G Tlr3 toll like receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624769:16,925,969...16,945,250
Ensembl chrNW_004624769:16,925,984...16,941,196 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO PMID:25158758 UniProt PMID:25158758 RGD:10054077 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (MGI:3656197|PMID:16633345) UniProt PMID:16633345 MGI:3656197 NCBI chrNW_004624755:24,976,375...24,995,150
Ensembl chrNW_004624755:24,976,361...25,001,397 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624767:18,859,990...18,869,083
Ensembl chrNW_004624767:18,860,017...18,868,581 		JBrowse link
toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624743:33,372,023...33,374,438
Ensembl chrNW_004624743:33,367,898...33,373,922 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex involved_in ISO (PMID:26189595) UniProt PMID:26189595 NCBI chrNW_004624737:12,022,081...12,052,128
Ensembl chrNW_004624737:12,022,419...12,052,131 		JBrowse link
G Ecsit ECSIT signaling integrator involved_in ISO (PMID:25371197) UniProt PMID:25371197 NCBI chrNW_004624828:3,264,054...3,276,270
Ensembl chrNW_004624828:3,264,149...3,269,030 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) UniProt PMID:14660645 NCBI chrNW_004624776:7,858,400...7,862,716
Ensembl chrNW_004624776:7,793,259...7,863,184 		JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 acts_upstream_of_or_within ISO (PMID:10549626) MGI PMID:10549626 NCBI chrNW_004624946:613,392...618,459
Ensembl chrNW_004624946:613,890...618,445 		JBrowse link
G Irak2 interleukin 1 receptor associated kinase 2 involved_in ISO (PMID:17878161) UniProt PMID:17878161 NCBI chrNW_004624731:5,294,464...5,348,426
Ensembl chrNW_004624731:5,294,431...5,348,481 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624832:4,611,445...4,616,319
Ensembl chrNW_004624832:4,612,374...4,616,276 		JBrowse link
G Lgals9 galectin 9 NOT|involved_in ISO (PMID:16116184) UniProt PMID:16116184 NCBI chrNW_004624786:478,048...491,086 JBrowse link
G LOC101722352 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:28630139) UniProt PMID:28630139 NCBI chrNW_004624733:6,304,454...6,341,827 JBrowse link
G Ly96 lymphocyte antigen 96 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624744:17,209,285...17,241,347
Ensembl chrNW_004624744:17,208,990...17,241,347 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:5913054|PMID:28098138) UniProt PMID:28098138 MGI:5913054 NCBI chrNW_004624886:4,029,318...4,168,797
Ensembl chrNW_004624886:4,027,178...4,168,902 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 involved_in ISO (PMID:25371197) UniProt PMID:25371197 NCBI chrNW_004624799:3,554,644...3,623,317
Ensembl chrNW_004624799:3,554,678...3,622,289 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624731:2,677,259...2,681,408
Ensembl chrNW_004624731:2,677,290...2,681,489 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO (PMID:29624734) MGI PMID:29624734 NCBI chrNW_004624795:1,553,582...1,558,110
Ensembl chrNW_004624795:1,553,037...1,558,197 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18261938) TreeGrafter
MGI
Ensembl		 PMID:18261938 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624838:1,384,337...1,387,602
Ensembl chrNW_004624838:1,384,204...1,390,205 		JBrowse link
G Nmi N-myc and STAT interactor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624866:4,230,258...4,263,156
Ensembl chrNW_004624866:4,229,535...4,263,688 		JBrowse link
G Oas1 2'-5'-oligoadenylate synthetase 1 involved_in ISO (PMID:30078389) ARUK-UCL PMID:30078389 NCBI chrNW_004624747:19,428,994...19,434,512
Ensembl chrNW_004624747:19,428,833...19,434,550 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:8,021,478...8,154,543
Ensembl chrNW_004624737:8,022,836...8,154,422 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:20,732,813...20,742,016
Ensembl chrNW_004624767:20,732,938...20,741,272 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894098) MGI PMID:11894098 NCBI chrNW_004624744:2,194,339...2,227,498
Ensembl chrNW_004624744:2,201,319...2,226,890 		JBrowse link
G S100a14 S100 calcium binding protein A14 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624885:3,529,813...3,531,314
Ensembl chrNW_004624885:3,529,026...3,532,182 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:8,975,216...8,982,825
Ensembl chrNW_004624786:8,974,587...9,007,986 		JBrowse link
G Tbk1 TANK binding kinase 1 involved_in ISO (PMID:28747347) UniProt PMID:28747347 NCBI chrNW_004624802:3,861,821...3,914,061
Ensembl chrNW_004624802:3,862,709...3,914,028 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (PMID:12471095) UniProt PMID:12471095 NCBI chrNW_004624828:4,964,199...4,973,465
Ensembl chrNW_004624828:4,971,093...4,973,198 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646 		JBrowse link
G Tlr4 toll like receptor 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25549946) MGI
Ensembl
TreeGrafter		 PMID:25549946 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
G Tmem126a transmembrane protein 126A acts_upstream_of_or_within ISO (PMID:25549946) MGI PMID:25549946 NCBI chrNW_004624845:4,264,497...4,272,973 JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 involved_in ISO (PMID:17088249) UniProt PMID:17088249 NCBI chrNW_004624777:1,124,389...1,222,450
Ensembl chrNW_004624777:1,124,204...1,158,324 		JBrowse link
G Traf3 TNF receptor associated factor 3 involved_in ISO (PMID:18222170) UniProt PMID:18222170 NCBI chrNW_004624734:1,728,353...1,820,345
Ensembl chrNW_004624734:1,728,255...1,786,010 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:25371197) UniProt PMID:25371197 NCBI chrNW_004624767:10,729,766...10,803,253
Ensembl chrNW_004624767:10,729,413...10,748,455 		JBrowse link
G Tril TLR4 interactor with leucine rich repeats involved_in ISO (PMID:19710467) UniProt PMID:19710467 NCBI chrNW_004624739:1,663,916...1,668,258
Ensembl chrNW_004624739:1,664,432...1,666,867 		JBrowse link
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tirap TIR domain containing adaptor protein NOT|involved_in ISO (MGI:3531416|PMID:12447442) BHF-UCL PMID:12447442 MGI:3531416 NCBI chrNW_004624812:433,540...445,517
Ensembl chrNW_004624812:439,319...446,646 		JBrowse link
G Tlr5 toll like receptor 5 involved_in ISO (PMID:17128265) BHF-UCL PMID:17128265 NCBI chrNW_004624835:5,495,723...5,503,462
Ensembl chrNW_004624835:5,500,461...5,503,034 		JBrowse link
toll-like receptor 7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) UniProt PMID:22842346 MGI:5437532 NCBI chrNW_004624733:32,521,318...32,527,499 JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:8,021,478...8,154,543
Ensembl chrNW_004624737:8,022,836...8,154,422 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:8,975,216...8,982,825
Ensembl chrNW_004624786:8,974,587...9,007,986 		JBrowse link
G Tlr7 toll like receptor 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624882:1,375,216...1,379,705 JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624767:18,859,990...18,869,083
Ensembl chrNW_004624767:18,860,017...18,868,581 		JBrowse link
toll-like receptor 8 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myd88 MYD88 innate immune signal transduction adaptor involved_in ISO (PMID:33718825) UniProt PMID:33718825 NCBI chrNW_004624731:2,677,259...2,681,408
Ensembl chrNW_004624731:2,677,290...2,681,489 		JBrowse link
G Tlr8 toll like receptor 8 involved_in ISO (PMID:12032557), (PMID:24942581), (PMID:33718825) UniProt PMID:12032557 PMID:24942581 PMID:33718825 NCBI chrNW_004624882:1,240,519...1,247,311
Ensembl chrNW_004624882:1,240,626...1,312,468 		JBrowse link
toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epg5 ectopic P-granules 5 autophagy tethering factor acts_upstream_of_positive_effect ISO (PMID:29130391) UniProt PMID:29130391 NCBI chrNW_004624778:9,490,744...9,614,289
Ensembl chrNW_004624778:9,491,258...9,614,299 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) UniProt PMID:22842346 MGI:5437532 NCBI chrNW_004624733:32,521,318...32,527,499 JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 involved_in ISO (MGI:5486235|PMID:23372731) UniProt PMID:23372731 MGI:5486235 NCBI chrNW_004624750:7,222,306...7,303,809
Ensembl chrNW_004624750:7,219,251...7,303,834 		JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:8,021,478...8,154,543
Ensembl chrNW_004624737:8,022,836...8,154,422 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (MGI:3656197|PMID:16633345) UniProt PMID:16633345 MGI:3656197 NCBI chrNW_004624755:24,976,375...24,995,150
Ensembl chrNW_004624755:24,976,361...25,001,397 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624767:18,859,990...18,869,083
Ensembl chrNW_004624767:18,860,017...18,868,581 		JBrowse link
toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO (PMID:20847273) MGI PMID:20847273 NCBI chrNW_004624869:2,459,370...2,741,529
Ensembl chrNW_004624869:2,459,947...2,741,328 		JBrowse link
G Bcl10 BCL10 immune signaling adaptor involved_in ISO (PMID:16831874) UniProt PMID:16831874 NCBI chrNW_004624742:12,210,333...12,222,533
Ensembl chrNW_004624742:12,210,360...12,221,759 		JBrowse link
G Cd86 CD86 molecule acts_upstream_of_or_within ISO (PMID:19734906) MGI PMID:19734906 NCBI chrNW_004624912:350,201...432,410
Ensembl chrNW_004624912:350,157...426,712 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30990796) Ensembl
MGI		 PMID:30990796 GO_REF:0000107 NCBI chrNW_004624767:20,519,054...20,525,311
Ensembl chrNW_004624767:20,519,313...20,524,554 		JBrowse link
G Irak3 interleukin 1 receptor associated kinase 3 ISO RGD PMID:27832756 RGD:34888235 NCBI chrNW_004624802:2,042,486...2,098,921
Ensembl chrNW_004624802:2,047,409...2,098,545 		JBrowse link
G LOC101703392 twinfilin-2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624730:6,004,706...6,020,876 JBrowse link
G LOC101707222 toll-like receptor 12 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624764:16,546,107...16,548,950 JBrowse link
G Lrrc19 leucine rich repeat containing 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19679103) Ensembl
MGI		 PMID:19679103 GO_REF:0000107 NCBI chrNW_004624736:31,208,583...31,218,754
Ensembl chrNW_004624736:31,206,168...31,218,754 		JBrowse link
G Ly96 lymphocyte antigen 96 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624744:17,209,285...17,241,347
Ensembl chrNW_004624744:17,208,990...17,241,347 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 involved_in ISO (MGI:3761050|PMID:17906627) UniProt PMID:17906627 MGI:3761050 NCBI chrNW_004624807:4,726,511...4,774,945
Ensembl chrNW_004624807:4,724,234...4,796,143 		JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624730:4,446,815...4,492,753
Ensembl chrNW_004624730:4,446,850...4,476,630 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:23728777)
(PMID:25124037)		 MGI PMID:23728777 PMID:25124037 NCBI chrNW_004624789:15,612,311...15,623,878
Ensembl chrNW_004624789:15,612,335...15,624,152 		JBrowse link
G Plcg2 phospholipase C gamma 2 involved_in ISO (MGI:3844414|PMID:19136564) ARUK-UCL PMID:19136564 MGI:3844414 NCBI chrNW_004624746:5,678,057...5,824,663
Ensembl chrNW_004624746:5,682,666...5,821,855 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 involved_in ISO (MGI:3761050|PMID:17906627) UniProt PMID:17906627 MGI:3761050 NCBI chrNW_004624829:4,978,181...5,087,493
Ensembl chrNW_004624829:4,983,282...5,087,485 		JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (PMID:12471095) UniProt PMID:12471095 NCBI chrNW_004624828:4,964,199...4,973,465
Ensembl chrNW_004624828:4,971,093...4,973,198 		JBrowse link
G Tifab TIFA inhibitor acts_upstream_of_negative_effect ISO (PMID:26458771) MGI PMID:26458771 NCBI chrNW_004624733:11,578,934...11,587,250 JBrowse link
G Tlr1 toll like receptor 1 involved_in ISO
IEA		 RGD
InterPro
TreeGrafter		 PMID:16973131 GO_REF:0000002 GO_REF:0000118 RGD:1643119 NCBI chrNW_004624840:7,287,772...7,349,282
Ensembl chrNW_004624840:7,287,781...7,290,162 		JBrowse link
G Tlr2 toll like receptor 2 involved_in IEA
ISO		 TreeGrafter
InterPro
UniProt
RGD		 PMID:16973131 PMID:18353287 GO_REF:0000002 GO_REF:0000104 GO_REF:0000118 RGD:1643119 RGD:5684896 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833 		JBrowse link
G Tlr3 toll like receptor 3 involved_in ISO
IEA		 RGD
InterPro
Ensembl
TreeGrafter		 PMID:16973131 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1643119 NCBI chrNW_004624769:16,925,969...16,945,250
Ensembl chrNW_004624769:16,925,984...16,941,196 		JBrowse link
G Tlr4 toll like receptor 4 involved_in ISO
IEA		 RGD
InterPro
Ensembl		 PMID:16973131 GO_REF:0000002 GO_REF:0000107 RGD:1643119 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
G Tlr5 toll like receptor 5 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624835:5,495,723...5,503,462
Ensembl chrNW_004624835:5,500,461...5,503,034 		JBrowse link
G Tlr6 toll like receptor 6 ISO RGD PMID:16973131 PMID:18353287 RGD:1643119 RGD:5684896 NCBI chrNW_004624840:7,323,022...7,349,334 JBrowse link
G Tlr7 toll like receptor 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624882:1,375,216...1,379,705 JBrowse link
G Tlr8 toll like receptor 8 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624882:1,240,519...1,247,311
Ensembl chrNW_004624882:1,240,626...1,312,468 		JBrowse link
G Traf3 TNF receptor associated factor 3 involved_in ISO (MGI:4839450|PMID:16306937) UniProt PMID:16306937 MGI:4839450 NCBI chrNW_004624734:1,728,353...1,820,345
Ensembl chrNW_004624734:1,728,255...1,786,010 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16415873) InterPro
MGI		 PMID:16415873 GO_REF:0000002 NCBI chrNW_004624767:18,859,990...18,869,083
Ensembl chrNW_004624767:18,860,017...18,868,581 		JBrowse link
toll-like receptor TLR1:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scimp SLP adaptor and CSK interacting membrane protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:8,975,216...8,982,825
Ensembl chrNW_004624786:8,974,587...9,007,986 		JBrowse link
toll-like receptor TLR6:TLR2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr2 toll like receptor 2 involved_in ISO (PMID:23626692) ComplexPortal PMID:23626692 NCBI chrNW_004624858:4,931,820...4,984,175
Ensembl chrNW_004624858:4,979,485...4,981,833 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (PMID:23626692) ComplexPortal PMID:23626692 NCBI chrNW_004624840:7,323,022...7,349,334 JBrowse link
TRAM-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101722352 TIR domain-containing adapter molecule 2 involved_in ISO (PMID:22685567)
(PMID:19412184)		 UniProt PMID:19412184 PMID:22685567 NCBI chrNW_004624733:6,304,454...6,341,827 JBrowse link
G Prkce protein kinase C epsilon involved_in ISO (MGI:3652658|PMID:16757566) UniProt PMID:16757566 MGI:3652658 NCBI chrNW_004624738:27,118,764...27,630,733
Ensembl chrNW_004624738:27,118,145...27,627,606 		JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 involved_in ISO (PMID:30883606) UniProt PMID:30883606 NCBI chrNW_004624737:28,633,815...28,675,773
Ensembl chrNW_004624737:28,634,079...28,686,886 		JBrowse link
TRIF-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule involved_in ISO (PMID:36232715) UniProt PMID:36232715 NCBI chrNW_004624736:9,991,851...10,017,047
Ensembl chrNW_004624736:9,996,156...10,013,814 		JBrowse link
G Cd300lf CD300 molecule like family member f involved_in ISO (PMID:22043923) UniProt PMID:22043923 NCBI chrNW_004624801:4,573,010...4,587,632
Ensembl chrNW_004624801:4,573,010...4,587,592 		JBrowse link
G Cd40 CD40 molecule involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624790:8,475,640...8,485,927
Ensembl chrNW_004624790:8,476,158...8,485,856 		JBrowse link
G Irf3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624832:4,611,445...4,616,319
Ensembl chrNW_004624832:4,612,374...4,616,276 		JBrowse link
G LOC101722352 TIR domain-containing adapter molecule 2 involved_in IEA TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624733:6,304,454...6,341,827 JBrowse link
G Ticam1 toll like receptor adaptor molecule 1 involved_in ISO (MGI:3718934|PMID:17658277)
(PMID:25636800)		 ParkinsonsUK-UCL
CACAO		 PMID:17658277 PMID:25636800 MGI:3718934 NCBI chrNW_004624828:4,964,199...4,973,465
Ensembl chrNW_004624828:4,971,093...4,973,198 		JBrowse link
G Tlr4 toll like receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624760:17,596,516...17,608,955
Ensembl chrNW_004624760:17,598,630...17,609,120 		JBrowse link
G Tlr6 toll like receptor 6 involved_in ISO (MGI:4438693|PMID:20037584) ARUK-UCL PMID:20037584 MGI:4438693 NCBI chrNW_004624840:7,323,022...7,349,334 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    cellular process 14237
      signal transduction 5415
        immune response-regulating signaling pathway 414
          immune response-activating signaling pathway + 405
          immune response-inhibiting signal transduction + 3
          immune response-regulating cell surface receptor signaling pathway + 256
Path 2
Term Annotations click to browse term
  biological_process 15093
    biological regulation 10618
      regulation of biological process 10301
        regulation of response to stimulus 3638
          regulation of immune response 762
            immune response-regulating signaling pathway 414
              immune response-activating signaling pathway + 405
              immune response-inhibiting signal transduction + 3
              immune response-regulating cell surface receptor signaling pathway + 256
paths to the root