Ipo5 (importin 5) - Rat Genome Database

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Gene: Ipo5 (importin 5) Heterocephalus glaber
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Symbol: Ipo5
Name: importin 5
RGD ID: 18921386
Description: ENCODES a protein that exhibits nuclear import signal receptor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cytoplasmic pattern recognition receptor signaling pathway (ortholog); NLS-bearing protein import into nucleus (ortholog); ASSOCIATED WITH Anal Atresia, Hypospadias, and Penoscrotal Inversion (ortholog); Animal Disease Models (ortholog); holoprosencephaly 5 (ortholog); FOUND IN cytosol (ortholog); Golgi apparatus (ortholog); nuclear membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: importin-5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479312,969,459 - 13,004,139 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479312,971,397 - 13,004,126 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ipo5Naked Mole-RatAnal Atresia, Hypospadias, and Penoscrotal Inversion  ISOIPO5 (Homo sapiens)8554872ClinVar Annotator: match by term: Anal atresia more ...ClinVarPMID:31690835
Ipo5Naked Mole-Ratholoprosencephaly 5  ISOIPO5 (Homo sapiens)8554872ClinVar Annotator: match by term: Holoprosencephaly 5ClinVarPMID:17274816 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ipo5Naked Mole-RatAnimal Disease Models  ISOIPO5 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:27602772
Ipo5Naked Mole-Ratlung adenocarcinoma  ISOIPO5 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:27602772


Biological Process

  

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ipo5Naked Mole-Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-0086150520179 UniProtGO_REF:0000044
Ipo5Naked Mole-Ratcytoplasm located_inIEAUniProtKB-KW:KW-0963150520179 UniProtGO_REF:0000043
Ipo5Naked Mole-Ratcytosol located_inISOIPO5 (Homo sapiens)9068941 HPAGO_REF:0000052
Ipo5Naked Mole-RatGolgi apparatus located_inISOIPO5 (Homo sapiens)9068941 HPAGO_REF:0000052
Ipo5Naked Mole-Ratnuclear membrane located_inISOIPO5 (Homo sapiens)9068941 HPAGO_REF:0000052
Ipo5Naked Mole-Ratnucleoplasm located_inISOIPO5 (Homo sapiens)9068941 HPAGO_REF:0000052
Ipo5Naked Mole-Ratnucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
Ipo5Naked Mole-Ratnucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044

Molecular Function
1 to 16 of 16 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ipo5Naked Mole-Ratnuclear import signal receptor activity enablesISOIPO5 (Homo sapiens)9068941 PMID:31340999UniProtPMID:31340999
Ipo5Naked Mole-Ratnuclear import signal receptor activity enablesISOIpo5 (Mus musculus)9068941 PMID:17143267GO_CentralPMID:17143267
Ipo5Naked Mole-Ratprotein binding enablesISOUniProtKB:P703159068941 PMID:15102471IntActPMID:15102471
Ipo5Naked Mole-Ratprotein binding enablesISOUniProtKB:Q8QZY39068941 PMID:17143267UniProtPMID:17143267
Ipo5Naked Mole-Ratprotein binding enablesISOPR:E9Q9D59068941 PMID:23055941MGIPMID:23055941
Ipo5Naked Mole-Ratprotein binding enablesISOUniProtKB:Q132779068941 PMID:29475951UniProtPMID:29475951
Ipo5Naked Mole-Ratprotein binding enablesISOUniProtKB:O95166 more ...9068941 PMID:20562859IntActPMID:20562859
Ipo5Naked Mole-Ratprotein binding enablesISOUniProtKB:P27958-PRO_00000375769068941 PMID:10799599IntActPMID:10799599
Ipo5Naked Mole-Ratprotein binding enablesISOPR:P628279068941 PMID:11809816MGIPMID:11809816
Ipo5Naked Mole-Ratprotein binding enablesISOUniProtKB:P428589068941 PMID:32814053IntActPMID:32814053
Ipo5Naked Mole-Ratprotein binding enablesISOUniProtKB:P605209068941 PMID:33961781IntActPMID:33961781
Ipo5Naked Mole-Ratprotein binding enablesISOUniProtKB:Q8NE359068941 PMID:22730302UniProtPMID:22730302
Ipo5Naked Mole-Ratprotein binding enablesISOUniProtKB:Q8BUE49068941 PMID:26689472UniProtPMID:26689472
Ipo5Naked Mole-Ratprotein binding enablesISOUniProtKB:Q9BUP39068941 PMID:15282309UniProtPMID:15282309
Ipo5Naked Mole-Ratprotein binding enablesISOUniProtKB:Q96AP09068941 PMID:21044950IntActPMID:21044950
Ipo5Naked Mole-Ratprotein binding enablesISOUniProtKB:P181249068941 PMID:20828572IntActPMID:20828572
1 to 16 of 16 rows

PMID:22301074   PMID:30032202  



Ipo5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479312,969,459 - 13,004,139 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479312,971,397 - 13,004,126 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
IPO5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381397,953,675 - 98,024,296 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1397,953,658 - 98,024,296 (+)EnsemblGRCh38hg38GRCh38
GRCh371398,605,929 - 98,676,550 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361397,403,930 - 97,474,551 (+)NCBINCBI36Build 36hg18NCBI36
Celera1379,453,341 - 79,523,964 (+)NCBICelera
Cytogenetic Map13q32.2NCBI
HuRef1379,203,817 - 79,274,125 (+)NCBIHuRef
CHM1_11398,576,302 - 98,646,937 (+)NCBICHM1_1
T2T-CHM13v2.01397,160,508 - 97,231,138 (+)NCBIT2T-CHM13v2.0
Ipo5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914121,134,271 - 121,185,451 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14121,148,636 - 121,185,411 (+)EnsemblGRCm39 Ensembl
GRCm3814120,896,840 - 120,948,046 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14120,911,224 - 120,947,999 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714121,310,416 - 121,347,268 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614120,046,431 - 120,083,179 (+)NCBIMGSCv36mm8
Celera14119,467,218 - 119,497,933 (+)NCBICelera
Cytogenetic Map14E4- E5NCBI
cM Map1464.81NCBI
Ipo5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815104,397,626 - 104,447,985 (+)NCBIGRCr8
mRatBN7.21597,990,755 - 98,041,074 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1598,005,299 - 98,041,126 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.015106,243,110 - 106,293,326 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15106,257,650 - 106,292,112 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015109,639,020 - 109,689,209 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415105,944,155 - 106,021,407 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.115105,983,354 - 106,037,884 (+)NCBI
Celera1596,799,493 - 96,849,477 (+)NCBICelera
Cytogenetic Map15q24NCBI
Ipo5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540412,416,755 - 12,459,452 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540412,416,755 - 12,480,281 (-)NCBIChiLan1.0ChiLan1.0
IPO5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21499,471,672 - 99,541,033 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11398,140,454 - 98,209,817 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01379,115,320 - 79,185,598 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11398,295,472 - 98,336,707 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1398,294,766 - 98,336,700 (+)Ensemblpanpan1.1panPan2
IPO5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12248,126,053 - 48,182,897 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2248,136,242 - 48,180,495 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2247,906,269 - 47,965,065 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02248,566,642 - 48,625,469 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2248,566,671 - 48,625,439 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12248,215,943 - 48,274,722 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02248,249,947 - 48,308,738 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02248,285,886 - 48,344,697 (+)NCBIUU_Cfam_GSD_1.0
Ipo5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945183,675,492 - 183,720,213 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647212,229,922 - 12,271,964 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647212,231,970 - 12,271,639 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IPO5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1167,004,109 - 67,060,551 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11167,019,299 - 67,059,375 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21174,138,179 - 74,173,295 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IPO5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1376,644,113 - 76,690,718 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl376,644,131 - 76,692,146 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604633,103,550 - 33,150,436 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

.






Ensembl Acc Id: ENSHGLT00000003652   ⟹   ENSHGLP00000003597
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462479312,969,459 - 13,004,139 (-)Ensembl
RefSeq Acc Id: XM_021239332   ⟹   XP_021094991
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479312,971,397 - 13,004,126 (-)NCBI
Protein RefSeqs XP_021094991 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003597
RefSeq Acc Id: XP_021094991   ⟸   XM_021239332
- UniProtKB: A0AAX6RCA4 (UniProtKB/TrEMBL),   G5C350 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000003597   ⟸   ENSHGLT00000003652



1 to 22 of 22 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSHGLG00000002656 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000003652 ENTREZGENE
Gene3D-CATH Leucine-rich Repeat Variant UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  HEAT UniProtKB/TrEMBL
  Importin_beta UniProtKB/TrEMBL
  Importin_rep_4 UniProtKB/TrEMBL
  Importin_rep_5 UniProtKB/TrEMBL
  Importin_rep_6 UniProtKB/TrEMBL
  TOG UniProtKB/TrEMBL
NCBI Gene Ipo5 ENTREZGENE
PANTHER IMPORTIN BETA UniProtKB/TrEMBL
Pfam HEAT UniProtKB/TrEMBL
  HEAT_EZ UniProtKB/TrEMBL
  Importin_rep_4 UniProtKB/TrEMBL
  Importin_rep_5 UniProtKB/TrEMBL
  Importin_rep_6 UniProtKB/TrEMBL
SMART TOG UniProtKB/TrEMBL
Superfamily-SCOP ARM repeat UniProtKB/TrEMBL
UniProt A0AAX6RCA4 ENTREZGENE, UniProtKB/TrEMBL
  G5C350 ENTREZGENE, UniProtKB/TrEMBL
1 to 22 of 22 rows