Aurkb (aurora kinase B) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Aurkb (aurora kinase B) Heterocephalus glaber
Analyze
Symbol: Aurkb
Name: aurora kinase B
RGD ID: 18908438
Description: ENCODES a protein that exhibits kinase binding (ortholog); protein kinase activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cell cycle G2/M phase transition (ortholog); cellular response to UV (ortholog); cleavage furrow formation (ortholog); ASSOCIATED WITH common variable immunodeficiency (ortholog); COVID-19 (ortholog); Diamond-Blackfan anemia (ortholog); FOUND IN chromocenter (ortholog); chromosome passenger complex (ortholog); chromosome, centromeric region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,765,610 - 10,775,112 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478610,769,797 - 10,775,142 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Aurkb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478610,765,610 - 10,775,112 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478610,769,797 - 10,775,142 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
AURKB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,204,731 - 8,210,575 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl178,204,733 - 8,210,600 (-)EnsemblGRCh38hg38GRCh38
GRCh37178,108,049 - 8,113,893 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,048,774 - 8,054,608 (-)NCBINCBI36Build 36hg18NCBI36
Build 34178,048,781 - 8,054,604NCBI
Celera178,136,501 - 8,142,334 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef178,003,833 - 8,009,723 (-)NCBIHuRef
CHM1_1178,117,184 - 8,123,078 (-)NCBICHM1_1
T2T-CHM13v2.0178,110,914 - 8,116,765 (-)NCBIT2T-CHM13v2.0
Aurkb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391168,936,477 - 68,942,490 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1168,936,473 - 68,942,490 (+)EnsemblGRCm39 Ensembl
GRCm381169,045,624 - 69,051,664 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,045,647 - 69,051,664 (+)EnsemblGRCm38mm10GRCm38
MGSCv371168,859,145 - 68,865,164 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361168,861,838 - 68,867,857 (+)NCBIMGSCv36mm8
Celera1175,989,163 - 75,995,182 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.32NCBI
Aurkb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81054,243,116 - 54,249,675 (+)NCBIGRCr8
mRatBN7.21053,744,290 - 53,750,831 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1053,745,142 - 53,750,837 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,407,027 - 58,412,691 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01057,895,622 - 57,901,286 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,403,795 - 53,409,462 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,625,860 - 55,632,399 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,626,741 - 55,634,991 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,368,674 - 55,375,204 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,798,710 - 55,804,367 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11055,812,332 - 55,817,990 (+)NCBI
Celera1052,911,399 - 52,917,056 (+)NCBICelera
Cytogenetic Map10q24NCBI
Aurkb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554678,715,136 - 8,723,932 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554678,715,387 - 8,720,889 (+)NCBIChiLan1.0ChiLan1.0
AURKB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21965,541,318 - 65,548,629 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11770,350,748 - 70,358,057 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01743,447,661 - 43,453,864 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11748,180,066 - 48,186,129 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1748,180,066 - 48,186,129 (+)Ensemblpanpan1.1panPan2
AURKB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1533,014,098 - 33,028,951 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl533,014,102 - 33,033,948 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha533,150,233 - 33,165,558 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0533,117,167 - 33,132,493 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl533,117,171 - 33,132,455 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1533,083,909 - 33,099,234 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0533,039,680 - 33,055,006 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0533,219,643 - 33,234,968 (-)NCBIUU_Cfam_GSD_1.0
Aurkb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,961,511 - 47,966,600 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,435,852 - 1,440,351 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,435,601 - 1,437,423 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AURKB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,410,177 - 53,423,225 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,410,833 - 53,426,165 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21255,886,065 - 55,894,911 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AURKB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,571,255 - 7,583,034 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,570,538 - 7,582,959 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605913,820,184 - 13,826,795 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000027427   ⟹   ENSHGLP00000027186
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462478610,765,610 - 10,775,112 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000027428   ⟹   ENSHGLP00000027187
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462478610,765,610 - 10,775,112 (-)Ensembl
RefSeq Acc Id: XM_004857488   ⟹   XP_004857545
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478610,769,925 - 10,775,129 (-)NCBI
RefSeq Acc Id: XM_013076752   ⟹   XP_012932206
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478610,769,925 - 10,774,718 (-)NCBI
RefSeq Acc Id: XM_013076753   ⟹   XP_012932207
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478610,769,925 - 10,775,091 (-)NCBI
RefSeq Acc Id: XM_021238324   ⟹   XP_021093983
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478610,769,797 - 10,775,142 (-)NCBI
RefSeq Acc Id: XM_021238325   ⟹   XP_021093984
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478610,769,925 - 10,775,064 (-)NCBI
RefSeq Acc Id: XM_021238326   ⟹   XP_021093985
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478610,769,925 - 10,774,952 (-)NCBI
RefSeq Acc Id: XM_021238327   ⟹   XP_021093986
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478610,769,797 - 10,772,137 (-)NCBI
RefSeq Acc Id: XP_021093983   ⟸   XM_021238324
- Peptide Label: isoform X1
- UniProtKB: G5B5F5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093986   ⟸   XM_021238327
- Peptide Label: isoform X4
RefSeq Acc Id: XP_004857545   ⟸   XM_004857488
- Peptide Label: isoform X3
- UniProtKB: A0A0N8EUG8 (UniProtKB/TrEMBL),   G5B5F5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012932207   ⟸   XM_013076753
- Peptide Label: isoform X1
- UniProtKB: G5B5F5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093984   ⟸   XM_021238325
- Peptide Label: isoform X3
- UniProtKB: A0A0N8EUG8 (UniProtKB/TrEMBL),   G5B5F5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093985   ⟸   XM_021238326
- Peptide Label: isoform X1
- UniProtKB: G5B5F5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012932206   ⟸   XM_013076752
- Peptide Label: isoform X2
- UniProtKB: G5B5F5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000027186   ⟸   ENSHGLT00000027427
Ensembl Acc Id: ENSHGLP00000027187   ⟸   ENSHGLT00000027428


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019335 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000027428 ENTREZGENE
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Aur UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report hgl:101713391 UniProtKB/TrEMBL
NCBI Gene Aurkb ENTREZGENE
PANTHER PTHR24350 UniProtKB/TrEMBL
  PTHR24350:SF4 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A0N8EUG8 ENTREZGENE, UniProtKB/TrEMBL
  G5B5F5 ENTREZGENE, UniProtKB/TrEMBL