Plcg1 (phospholipase C gamma 1) - Rat Genome Database

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Gene: Plcg1 (phospholipase C gamma 1) Heterocephalus glaber
Analyze
Symbol: Plcg1
Name: phospholipase C gamma 1
RGD ID: 18922956
Description: ENCODES a protein that exhibits calcium-dependent phospholipase C activity (ortholog); glutamate receptor binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN calcium ion transport (ortholog); calcium-mediated signaling (ortholog); cell migration (ortholog); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH acute myocardial infarction (ortholog); adult T-cell leukemia/lymphoma (ortholog); Alzheimer's disease (ortholog); FOUND IN cell projection (ortholog); cell-cell junction (ortholog); clathrin-coated vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249191,766,149 - 1,803,097 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249191,766,533 - 1,800,130 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Plcg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249191,766,149 - 1,803,097 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249191,766,533 - 1,800,130 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PLCG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382041,137,543 - 41,177,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2041,136,960 - 41,196,801 (+)EnsemblGRCh38hg38GRCh38
GRCh372039,766,183 - 39,806,266 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362039,199,575 - 39,237,771 (+)NCBINCBI36Build 36hg18NCBI36
Build 342039,199,574 - 39,237,771NCBI
Celera2036,476,730 - 36,514,924 (+)NCBICelera
Cytogenetic Map20q12NCBI
HuRef2036,504,215 - 36,542,409 (+)NCBIHuRef
CHM1_12039,670,573 - 39,708,755 (+)NCBICHM1_1
T2T-CHM13v2.02042,868,611 - 42,909,312 (+)NCBIT2T-CHM13v2.0
Plcg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392160,573,230 - 160,617,680 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2160,573,220 - 160,617,680 (+)EnsemblGRCm39 Ensembl
GRCm382160,731,310 - 160,775,760 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2160,731,300 - 160,775,760 (+)EnsemblGRCm38mm10GRCm38
MGSCv372160,557,046 - 160,601,496 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362160,422,751 - 160,467,201 (+)NCBIMGSCv36mm8
Celera2166,663,373 - 166,707,819 (+)NCBICelera
Cytogenetic Map2H2NCBI
cM Map280.97NCBI
Plcg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83169,805,299 - 169,836,040 (+)NCBIGRCr8
mRatBN7.23149,385,587 - 149,416,330 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3149,385,587 - 149,416,330 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3153,198,699 - 153,229,463 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03161,698,084 - 161,728,848 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03159,437,731 - 159,468,477 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03156,727,642 - 156,758,307 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3156,727,642 - 156,758,307 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03162,957,126 - 162,987,842 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43151,522,949 - 151,553,998 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13151,428,984 - 151,460,034 (+)NCBI
Celera3148,059,477 - 148,090,220 (+)NCBICelera
RH 3.4 Map31368.6RGD
Cytogenetic Map3q42NCBI
Plcg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544515,787,496 - 15,823,859 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544515,787,496 - 15,823,859 (-)NCBIChiLan1.0ChiLan1.0
PLCG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22146,878,783 - 46,917,555 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12046,871,882 - 46,910,654 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02037,477,077 - 37,515,854 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12038,577,199 - 38,615,149 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2038,572,709 - 38,615,145 (+)Ensemblpanpan1.1panPan2
PLCG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12429,198,536 - 29,213,899 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2429,198,556 - 29,214,714 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2428,823,106 - 28,859,401 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02429,883,241 - 29,919,530 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2429,883,201 - 29,919,502 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12429,152,120 - 29,188,420 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02429,256,001 - 29,292,271 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02429,752,157 - 29,788,483 (+)NCBIUU_Cfam_GSD_1.0
Plcg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640178,117,909 - 178,150,680 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936561598,382 - 631,581 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936561598,372 - 631,575 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1743,810,048 - 43,844,554 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11743,810,003 - 43,844,553 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21749,203,540 - 49,238,416 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1222,599,547 - 22,638,394 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605071,416,788 - 71,455,730 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000002763   ⟹   ENSHGLP00000002709
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249191,766,149 - 1,803,097 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000002764   ⟹   ENSHGLP00000002710
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249191,766,613 - 1,798,798 (+)Ensembl
RefSeq Acc Id: XM_004874031   ⟹   XP_004874088
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249191,766,613 - 1,800,130 (+)NCBI
RefSeq Acc Id: XM_004874032   ⟹   XP_004874089
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249191,766,613 - 1,800,130 (+)NCBI
RefSeq Acc Id: XR_002391930
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249191,766,533 - 1,798,398 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004874088 (Get FASTA)   NCBI Sequence Viewer  
  XP_004874089 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000002709
  ENSHGLP00100022349
GenBank Protein JAN97991 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004874088   ⟸   XM_004874031
- Peptide Label: isoform X1
- UniProtKB: G5C9N1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004874089   ⟸   XM_004874032
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J3L4 (UniProtKB/TrEMBL),   G5C9N1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000002710   ⟸   ENSHGLT00000002764
Ensembl Acc Id: ENSHGLP00000002709   ⟸   ENSHGLT00000002763


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002041 Ensembl, ENTREZGENE
  ENSHGLG00100016440 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000002763 ENTREZGENE
  ENSHGLT00100022582 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.20.20.190 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PI-PLC_fam UniProtKB/TrEMBL
  PLC-gamma UniProtKB/TrEMBL
  PLC-gamma_C-SH2 UniProtKB/TrEMBL
  PLC-gamma_N-SH2 UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/TrEMBL
  PLCgamma1_SH3 UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/TrEMBL
  PLipase_C_Pinositol-sp_Y UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene Plcg1 ENTREZGENE
PANTHER PTHR10336 UniProtKB/TrEMBL
  PTHR10336:SF173 UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  PI-PLC-X UniProtKB/TrEMBL
  PI-PLC-Y UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
PIRSF PLC-gamma UniProtKB/TrEMBL
PRINTS PHPHLIPASEC UniProtKB/TrEMBL
  SH2DOMAIN UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  PIPLC_X_DOMAIN UniProtKB/TrEMBL
  PIPLC_Y_DOMAIN UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART PLCXc UniProtKB/TrEMBL
  PLCYc UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
  SSF51695 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A0P6J3L4 ENTREZGENE, UniProtKB/TrEMBL
  G5C9N1 ENTREZGENE, UniProtKB/TrEMBL