Rab7b (RAB7B, member RAS oncogene family) - Rat Genome Database

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Gene: Rab7b (RAB7B, member RAS oncogene family) Heterocephalus glaber
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Symbol: Rab7b
Name: RAB7B, member RAS oncogene family
RGD ID: 18932504
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); INVOLVED IN cellular response to type II interferon (ortholog); late endosome to Golgi transport (ortholog); negative regulation of toll-like receptor 4 signaling pathway (ortholog); ASSOCIATED WITH Acute Coronary Syndrome (ortholog); autistic disorder (ortholog); osteoporosis (ortholog); FOUND IN Golgi apparatus (ortholog); trans-Golgi network (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein Rab-7b
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248075,307,440 - 5,334,945 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248075,307,361 - 5,334,578 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rab7b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248075,307,440 - 5,334,945 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248075,307,361 - 5,334,578 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RAB7B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381205,976,740 - 206,003,395 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1205,976,740 - 206,003,461 (-)EnsemblGRCh38hg38GRCh38
Celera1179,083,656 - 179,111,173 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
T2T-CHM13v2.01205,240,788 - 205,267,388 (-)NCBIT2T-CHM13v2.0
Rab7b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391131,616,412 - 131,646,288 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1131,616,433 - 131,643,177 (+)EnsemblGRCm39 Ensembl
GRCm381131,688,681 - 131,715,443 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1131,688,695 - 131,715,439 (+)EnsemblGRCm38mm10GRCm38
MGSCv371133,585,272 - 133,610,041 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361133,516,271 - 133,540,610 (+)NCBIMGSCv36mm8
Celera1134,288,561 - 134,315,745 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map157.18NCBI
Rab7b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81345,673,396 - 45,699,798 (+)NCBIGRCr8
mRatBN7.21343,121,168 - 43,147,581 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1343,121,226 - 43,147,581 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1345,724,566 - 45,751,219 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01347,012,704 - 47,039,362 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01344,277,285 - 44,303,944 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01348,456,143 - 48,483,714 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1348,455,923 - 48,482,138 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01353,528,328 - 53,554,460 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41344,620,063 - 44,636,864 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1343,459,652 - 43,485,905 (+)NCBICelera
Cytogenetic Map13q13NCBI
Rab7b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540641,615,302 - 41,638,151 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540641,615,302 - 41,638,157 (-)NCBIChiLan1.0ChiLan1.0
RAB7B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2143,366,553 - 43,393,623 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1143,332,079 - 43,359,104 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01181,584,814 - 181,611,831 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11185,868,040 - 185,894,691 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1185,867,145 - 185,894,691 (-)Ensemblpanpan1.1panPan2
RAB7B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1382,333,939 - 2,359,531 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl382,335,535 - 2,359,469 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha382,426,274 - 2,452,097 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0382,331,177 - 2,356,692 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl382,331,172 - 2,356,652 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1382,324,856 - 2,350,846 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0382,716,580 - 2,742,361 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0382,917,536 - 2,943,551 (-)NCBIUU_Cfam_GSD_1.0
Rab7b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934469,264,259 - 69,283,993 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365576,504,509 - 6,519,219 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365576,504,562 - 6,519,219 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB7B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl966,635,638 - 66,666,036 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1966,635,636 - 66,666,034 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2972,916,252 - 72,946,414 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAB7B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12523,341,090 - 23,367,414 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2523,341,490 - 23,367,398 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605524,038,503 - 24,064,596 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000006992   ⟹   ENSHGLP00000006908
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248075,307,440 - 5,334,945 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000006993   ⟹   ENSHGLP00000006909
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248075,307,440 - 5,334,945 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000006994   ⟹   ENSHGLP00000006910
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248075,315,792 - 5,333,497 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000006995   ⟹   ENSHGLP00000006911
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248075,315,792 - 5,330,312 (+)Ensembl
RefSeq Acc Id: XM_004862074   ⟹   XP_004862131
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248075,307,371 - 5,334,578 (+)NCBI
RefSeq Acc Id: XM_021242398   ⟹   XP_021098057
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248075,307,365 - 5,334,578 (+)NCBI
RefSeq Acc Id: XM_021242399   ⟹   XP_021098058
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248075,307,361 - 5,334,578 (+)NCBI
RefSeq Acc Id: XM_021242400   ⟹   XP_021098059
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248075,307,361 - 5,334,578 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004862131 (Get FASTA)   NCBI Sequence Viewer  
  XP_021098057 (Get FASTA)   NCBI Sequence Viewer  
  XP_021098058 (Get FASTA)   NCBI Sequence Viewer  
  XP_021098059 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000006908
  ENSHGLP00000006909
GenBank Protein JAO01081 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021098058   ⟸   XM_021242399
- Peptide Label: isoform X1
- UniProtKB: G5BX52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098059   ⟸   XM_021242400
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021098057   ⟸   XM_021242398
- Peptide Label: isoform X1
- UniProtKB: G5BX52 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004862131   ⟸   XM_004862074
- Peptide Label: isoform X2
- UniProtKB: G5BX52 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000006909   ⟸   ENSHGLT00000006993
Ensembl Acc Id: ENSHGLP00000006910   ⟸   ENSHGLT00000006994
Ensembl Acc Id: ENSHGLP00000006911   ⟸   ENSHGLT00000006995
Ensembl Acc Id: ENSHGLP00000006908   ⟸   ENSHGLT00000006992


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005045 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000006992 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLT00000006993 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
NCBI Gene Rab7b ENTREZGENE
PANTHER RAB FAMILY UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-7B UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE ARF UniProtKB/TrEMBL
  RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0P6K691_HETGA UniProtKB/TrEMBL
  G5BX52 ENTREZGENE, UniProtKB/TrEMBL