Zdhhc12 (zinc finger DHHC-type palmitoyltransferase 12) - Rat Genome Database

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Gene: Zdhhc12 (zinc finger DHHC-type palmitoyltransferase 12) Heterocephalus glaber
Analyze
Symbol: Zdhhc12
Name: zinc finger DHHC-type palmitoyltransferase 12 (Ensembl:zinc finger DHHC-type containing 12)
RGD ID: 18921397
Description: ENCODES a protein that exhibits acyltransferase activity (inferred); palmitoyltransferase activity (inferred); protein-cysteine S-palmitoyltransferase activity (inferred); INVOLVED IN gephyrin clustering involved in postsynaptic density assembly (inferred); negative regulation of NLRP3 inflammasome complex assembly (inferred); positive regulation of synaptic transmission, GABAergic (inferred); ASSOCIATED WITH genetic disease (ortholog); primary coenzyme Q10 deficiency 7 (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable palmitoyltransferase ZDHHC12; Putative palmitoyltransferase ZDHHC12; zinc finger DHHC-type containing 12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247606,273,994 - 6,276,776 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247606,273,989 - 6,276,788 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Zdhhc12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247606,273,994 - 6,276,776 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247606,273,989 - 6,276,788 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ZDHHC12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389128,720,873 - 128,724,127 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9128,720,870 - 128,724,127 (-)EnsemblGRCh38hg38GRCh38
GRCh379131,483,152 - 131,486,406 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,522,969 - 130,526,229 (-)NCBINCBI36Build 36hg18NCBI36
Build 349128,562,704 - 128,565,962NCBI
Celera9102,133,934 - 102,137,194 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9101,092,809 - 101,095,741 (-)NCBIHuRef
CHM1_19131,634,114 - 131,637,374 (-)NCBICHM1_1
T2T-CHM13v2.09140,925,640 - 140,928,894 (-)NCBIT2T-CHM13v2.0
Zdhhc12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39229,980,956 - 29,983,647 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl229,980,956 - 29,983,660 (-)EnsemblGRCm39 Ensembl
GRCm38230,090,943 - 30,093,638 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl230,090,944 - 30,093,648 (-)EnsemblGRCm38mm10GRCm38
MGSCv37229,946,464 - 29,949,155 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36229,912,953 - 29,915,644 (-)NCBIMGSCv36mm8
Celera229,794,461 - 29,797,152 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.15NCBI
Zdhhc12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8333,761,338 - 33,764,207 (-)NCBIGRCr8
mRatBN7.2313,363,504 - 13,366,383 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,363,504 - 13,366,474 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx316,438,171 - 16,440,875 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0325,023,137 - 25,025,841 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,273,727 - 23,276,432 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,656,397 - 8,659,102 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,656,412 - 8,659,102 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0314,008,555 - 14,011,260 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.439,096,320 - 9,099,025 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.139,096,621 - 9,099,325 (-)NCBI
Celera38,137,016 - 8,139,720 (-)NCBICelera
Cytogenetic Map3p12NCBI
Zdhhc12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555701,131,234 - 1,133,909 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555701,131,234 - 1,133,909 (-)NCBIChiLan1.0ChiLan1.0
ZDHHC12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21110,626,390 - 10,629,830 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1910,628,740 - 10,632,191 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0999,844,535 - 99,847,806 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,510,734 - 128,514,005 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,510,739 - 128,514,004 (-)Ensemblpanpan1.1panPan2
ZDHHC12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1954,877,188 - 54,880,579 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl954,877,110 - 54,880,553 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,072,606 - 54,075,998 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0955,798,243 - 55,801,640 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl955,798,303 - 55,801,636 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,558,838 - 54,562,230 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0954,871,500 - 54,874,882 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0954,965,010 - 54,968,403 (+)NCBIUU_Cfam_GSD_1.0
Zdhhc12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,432,761 - 196,435,370 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,199,742 - 16,203,858 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648716,201,288 - 16,203,818 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZDHHC12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1269,081,272 - 269,084,840 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11269,081,274 - 269,084,853 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21303,105,133 - 303,106,855 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZDHHC12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,419,784 - 9,423,091 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl129,419,852 - 9,422,774 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366609644,892 - 48,185 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000020356   ⟹   ENSHGLP00000020155
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247606,273,994 - 6,276,776 (+)Ensembl
RefSeq Acc Id: XM_004849191   ⟹   XP_004849248
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247606,273,993 - 6,276,788 (+)NCBI
RefSeq Acc Id: XM_004849192   ⟹   XP_004849249
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247606,273,989 - 6,276,776 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004849248 (Get FASTA)   NCBI Sequence Viewer  
  XP_004849249 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA99951 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000020155
  ENSHGLP00000030551
GenBank Protein JAO01787 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004849249   ⟸   XM_004849192
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004849248   ⟸   XM_004849191
- Peptide Label: isoform X1
- UniProtKB: G5ASE1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000020155   ⟸   ENSHGLT00000020356


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014429 Ensembl, ENTREZGENE
  ENSHGLG00000043046 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000020356 ENTREZGENE
  ENSHGLT00000091786 UniProtKB/TrEMBL
InterPro Palmitoyltrfase_DHHC UniProtKB/TrEMBL
KEGG Report hgl:101719837 UniProtKB/TrEMBL
NCBI Gene Zdhhc12 ENTREZGENE
PANTHER PALMITOYLTRANSFERASE ZDHHC12 UniProtKB/TrEMBL
  ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam DHHC UniProtKB/TrEMBL
PROSITE DHHC UniProtKB/TrEMBL
UniProt G5ASE1 ENTREZGENE, UniProtKB/TrEMBL