Gps2 (G protein pathway suppressor 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Gps2 (G protein pathway suppressor 2) Heterocephalus glaber
Analyze
Symbol: Gps2
Name: G protein pathway suppressor 2
RGD ID: 18932773
Description: ENCODES a protein that exhibits cyclin binding (ortholog); transcription coactivator activity (ortholog); transcription corepressor activity (ortholog); INVOLVED IN B cell differentiation (ortholog); negative regulation of B cell receptor signaling pathway (ortholog); negative regulation of fat cell differentiation (ortholog); ASSOCIATED WITH common variable immunodeficiency (ortholog); congenital myasthenic syndrome 2A (ortholog); dyskeratosis congenita (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247869,938,384 - 9,941,235 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247869,938,384 - 9,941,210 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Gps2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247869,938,384 - 9,941,235 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247869,938,384 - 9,941,210 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
GPS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,312,661 - 7,315,360 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,311,324 - 7,315,564 (-)EnsemblGRCh38hg38GRCh38
GRCh37177,215,980 - 7,218,679 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,156,702 - 7,159,382 (-)NCBINCBI36Build 36hg18NCBI36
Build 34177,156,701 - 7,159,382NCBI
Celera177,241,919 - 7,244,599 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,110,027 - 7,112,707 (-)NCBIHuRef
CHM1_1177,224,746 - 7,227,426 (-)NCBICHM1_1
T2T-CHM13v2.0177,216,645 - 7,219,344 (-)NCBIT2T-CHM13v2.0
Gps2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,804,805 - 69,807,882 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,804,714 - 69,807,417 (+)EnsemblGRCm39 Ensembl
GRCm381169,913,980 - 69,917,056 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,913,888 - 69,916,591 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,727,694 - 69,730,093 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,730,387 - 69,732,786 (+)NCBIMGSCv36mm8
Celera1177,462,080 - 77,464,479 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.92NCBI
Gps2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,136,043 - 55,139,106 (+)NCBIGRCr8
mRatBN7.21054,637,360 - 54,640,542 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,637,455 - 54,640,650 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,300,045 - 59,302,565 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,788,617 - 58,791,137 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,295,924 - 54,298,444 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,524,327 - 56,527,447 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,524,468 - 56,526,987 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,269,440 - 56,272,538 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,757,674 - 56,760,194 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1053,791,431 - 53,793,951 (+)NCBICelera
Cytogenetic Map10q24NCBI
Gps2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554679,600,829 - 9,603,606 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554679,600,829 - 9,604,148 (+)NCBIChiLan1.0ChiLan1.0
GPS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21914,909,000 - 14,911,982 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11716,874,828 - 16,878,377 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,346,766 - 7,349,682 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,333,474 - 7,336,378 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,333,571 - 7,335,871 (-)Ensemblpanpan1.1panPan2
GPS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,273,169 - 32,275,915 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl532,273,173 - 32,275,580 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,410,901 - 32,413,619 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,378,257 - 32,380,975 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,378,257 - 32,380,591 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,343,689 - 32,346,407 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,302,465 - 32,305,182 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,479,500 - 32,482,218 (-)NCBIUU_Cfam_GSD_1.0
Gps2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,135,044 - 47,137,738 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936595609,232 - 611,845 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936595608,730 - 611,871 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,664,875 - 52,667,610 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,664,869 - 52,667,643 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23139,940,663 - 139,943,454 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GPS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,690,831 - 6,694,245 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl166,686,667 - 6,693,804 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605914,716,459 - 14,719,347 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000015818   ⟹   ENSHGLP00000015654
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247869,938,384 - 9,941,235 (-)Ensembl
RefSeq Acc Id: XM_013076828   ⟹   XP_012932282
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247869,938,384 - 9,941,210 (-)NCBI
Protein Sequences
Protein RefSeqs XP_012932282 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB04473 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000015654
  ENSHGLP00100041528
RefSeq Acc Id: XP_012932282   ⟸   XM_013076828
- UniProtKB: G5B5B2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000015654   ⟸   ENSHGLT00000015818


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011192 Ensembl, ENTREZGENE
  ENSHGLG00100043788 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000015818 ENTREZGENE
  ENSHGLT00100054282 UniProtKB/TrEMBL
InterPro GPS2 UniProtKB/TrEMBL
KEGG Report hgl:101716315 UniProtKB/TrEMBL
NCBI Gene Gps2 ENTREZGENE
PANTHER G PROTEIN PATHWAY SUPPRESSOR 2 UniProtKB/TrEMBL
  PTHR22654 UniProtKB/TrEMBL
Pfam G_path_suppress UniProtKB/TrEMBL
UniProt G5B5B2 ENTREZGENE, UniProtKB/TrEMBL