Tnip3 (TNFAIP3 interacting protein 3) - Rat Genome Database

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Gene: Tnip3 (TNFAIP3 interacting protein 3) Heterocephalus glaber
Analyze
Symbol: Tnip3
Name: TNFAIP3 interacting protein 3
RGD ID: 18929869
Description: ENCODES a protein that exhibits polyubiquitin modification-dependent protein binding (ortholog); INVOLVED IN MyD88-independent toll-like receptor signaling pathway (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); toll-like receptor 4 signaling pathway (ortholog); ASSOCIATED WITH neurodevelopmental disorder with hearing loss, seizures, and brain abnormalities (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TNFAIP3-interacting protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247771,124,204 - 1,158,324 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247771,124,389 - 1,222,450 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Tnip3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247771,124,204 - 1,158,324 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247771,124,389 - 1,222,450 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TNIP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384121,131,408 - 121,227,483 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4121,131,408 - 121,227,466 (-)EnsemblGRCh38hg38GRCh38
GRCh374122,052,563 - 122,148,638 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364122,272,017 - 122,304,926 (-)NCBINCBI36Build 36hg18NCBI36
Build 344122,410,171 - 122,443,081NCBI
Celera4119,438,060 - 119,523,157 (-)NCBICelera
Cytogenetic Map4q27NCBI
HuRef4117,779,606 - 117,875,679 (-)NCBIHuRef
CHM1_14122,029,103 - 122,125,192 (-)NCBICHM1_1
T2T-CHM13v2.04124,435,731 - 124,531,810 (-)NCBIT2T-CHM13v2.0
Tnip3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39665,567,382 - 65,611,024 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl665,502,297 - 65,611,024 (+)EnsemblGRCm39 Ensembl
GRCm38665,590,398 - 65,634,040 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl665,525,313 - 65,634,040 (+)EnsemblGRCm38mm10GRCm38
MGSCv37665,540,392 - 65,584,034 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36665,520,173 - 65,563,618 (+)NCBIMGSCv36mm8
Celera667,716,507 - 67,760,116 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map630.26NCBI
Tnip3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8496,197,019 - 96,237,357 (+)NCBIGRCr8
mRatBN7.2494,867,258 - 94,908,780 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl494,811,097 - 94,907,605 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0496,386,207 - 96,490,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl496,449,351 - 96,492,871 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04161,172,197 - 161,277,545 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4495,130,822 - 95,170,426 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera489,547,296 - 89,643,845 (+)NCBICelera
Cytogenetic Map4q31NCBI
Tnip3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542819,479,638 - 19,511,758 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542819,479,633 - 19,511,738 (+)NCBIChiLan1.0ChiLan1.0
TNIP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23118,923,914 - 119,008,116 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14119,208,280 - 119,292,441 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04113,343,082 - 113,428,022 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14124,481,710 - 124,577,599 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4124,481,721 - 124,577,599 (-)Ensemblpanpan1.1panPan2
TNIP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11918,857,719 - 18,960,760 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1918,853,168 - 18,960,760 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1919,080,344 - 19,183,678 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01918,983,923 - 19,087,318 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1918,979,685 - 19,087,318 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11918,943,691 - 19,046,633 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01919,214,924 - 19,317,879 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01919,693,807 - 19,796,756 (+)NCBIUU_Cfam_GSD_1.0
Tnip3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530166,410,411 - 66,441,702 (+)NCBIHiC_Itri_2
TNIP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8102,892,366 - 102,991,848 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18102,892,427 - 102,990,902 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28110,275,634 - 110,377,144 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNIP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1768,416,674 - 68,519,097 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl768,422,328 - 68,454,143 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603747,385,284 - 47,482,964 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000005066   ⟹   ENSHGLP00000005001
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247771,124,204 - 1,158,324 (-)Ensembl
RefSeq Acc Id: XM_004854924   ⟹   XP_004854981
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247771,124,389 - 1,222,450 (-)NCBI
RefSeq Acc Id: XM_021236442   ⟹   XP_021092101
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247771,124,389 - 1,222,450 (-)NCBI
RefSeq Acc Id: XM_021236443   ⟹   XP_021092102
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247771,124,389 - 1,158,389 (-)NCBI
RefSeq Acc Id: XM_021236444   ⟹   XP_021092103
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247771,124,389 - 1,181,226 (-)NCBI
RefSeq Acc Id: XM_021236445   ⟹   XP_021092104
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247771,124,389 - 1,158,415 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004854981 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092101 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092102 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092103 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092104 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005001
GenBank Protein JAO02305 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021092101   ⟸   XM_021236442
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004854981   ⟸   XM_004854924
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JKU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092103   ⟸   XM_021236444
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JKU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092104   ⟸   XM_021236445
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JKU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092102   ⟸   XM_021236443
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JKU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000005001   ⟸   ENSHGLT00000005066


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003668 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000005066 ENTREZGENE
Gene3D-CATH Nemo cc2-lz domain - 1d5 darpin complex UniProtKB/TrEMBL
InterPro CC2-LZ_dom UniProtKB/TrEMBL
NCBI Gene Tnip3 ENTREZGENE
PANTHER PTHR31882:SF2 UniProtKB/TrEMBL
  TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER UniProtKB/TrEMBL
Pfam CC2-LZ UniProtKB/TrEMBL
UniProt A0A0P6JKU0 ENTREZGENE, UniProtKB/TrEMBL