Tarbp2 (TARBP2 subunit of RISC loading complex) - Rat Genome Database

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Gene: Tarbp2 (TARBP2 subunit of RISC loading complex) Heterocephalus glaber
Analyze
Symbol: Tarbp2
Name: TARBP2 subunit of RISC loading complex
RGD ID: 18932996
Description: ENCODES a protein that exhibits enzyme binding (ortholog); identical protein binding (ortholog); pre-miRNA binding (ortholog); INVOLVED IN miRNA processing (ortholog); multicellular organism growth (ortholog); negative regulation of cytoplasmic pattern recognition receptor signaling pathway (ortholog); PARTICIPATES IN microRNA pathway; ASSOCIATED WITH genetic disease (ortholog); Microsatellite Instability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); RISC-loading complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: RISC-loading complex subunit TARBP2; TARBP2, RISC loading complex RNA binding subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,597,428 - 1,603,504 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,598,422 - 1,603,494 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Tarbp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,597,428 - 1,603,504 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,598,422 - 1,603,494 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TARBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,500,923 - 53,506,431 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,500,921 - 53,506,431 (+)EnsemblGRCh38hg38GRCh38
GRCh371253,894,707 - 53,900,215 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361252,180,972 - 52,186,482 (+)NCBINCBI36Build 36hg18NCBI36
Build 341252,180,971 - 52,186,480NCBI
Celera1253,545,063 - 53,550,573 (+)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,934,287 - 50,939,797 (+)NCBIHuRef
CHM1_11253,861,761 - 53,867,271 (+)NCBICHM1_1
T2T-CHM13v2.01253,466,928 - 53,472,436 (+)NCBIT2T-CHM13v2.0
Tarbp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,423,327 - 102,432,112 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,426,627 - 102,432,111 (+)EnsemblGRCm39 Ensembl
GRCm3815102,516,077 - 102,523,676 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,518,192 - 102,523,676 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715102,348,677 - 102,354,107 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,346,493 - 102,351,708 (+)NCBIMGSCv36mm8
Celera15104,676,011 - 104,681,441 (+)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1557.65NCBI
Tarbp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,527,710 - 135,532,826 (+)NCBIGRCr8
mRatBN7.27133,649,118 - 133,654,306 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,649,090 - 133,654,314 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,404,936 - 135,410,051 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,634,303 - 137,639,418 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,620,556 - 137,625,671 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07144,121,688 - 144,126,860 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,121,744 - 144,126,857 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,912,728 - 141,918,855 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,272,043 - 141,273,188 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17141,348,156 - 141,349,625 (+)NCBI
Celera7130,076,808 - 130,081,909 (+)NCBICelera
Cytogenetic Map7q36NCBI
Tarbp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458793,759 - 798,806 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955458793,753 - 798,755 (+)NCBIChiLan1.0ChiLan1.0
TARBP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21040,678,185 - 40,683,408 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11240,674,949 - 40,681,391 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,246,937 - 35,253,378 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,031,822 - 36,038,080 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,031,818 - 36,038,008 (-)Ensemblpanpan1.1panPan2
TARBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,715,157 - 1,720,050 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,715,158 - 1,726,885 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,530,279 - 44,535,121 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,719,078 - 1,723,920 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl271,719,077 - 1,723,754 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,736,610 - 1,741,453 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,719,877 - 1,724,720 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,931,979 - 44,936,821 (+)NCBIUU_Cfam_GSD_1.0
Tarbp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,384,789 - 62,390,032 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,774,213 - 10,796,268 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,774,793 - 10,780,041 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TARBP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,718,688 - 18,723,839 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,718,588 - 18,723,843 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2519,154,223 - 19,159,472 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TARBP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,601,634 - 49,607,097 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1149,602,113 - 49,606,816 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037196,446,953 - 196,453,171 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000001728   ⟹   ENSHGLP00000001683
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249041,597,428 - 1,603,504 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000001729   ⟹   ENSHGLP00000001684
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249041,598,543 - 1,603,221 (+)Ensembl
RefSeq Acc Id: XM_013068476   ⟹   XP_012923930
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,598,422 - 1,603,494 (+)NCBI
RefSeq Acc Id: XM_021250658   ⟹   XP_021106317
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,598,422 - 1,603,494 (+)NCBI
RefSeq Acc Id: XM_021250659   ⟹   XP_021106318
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,598,704 - 1,603,494 (+)NCBI
RefSeq Acc Id: XM_021250660   ⟹   XP_021106319
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,598,422 - 1,603,494 (+)NCBI
RefSeq Acc Id: XM_021250661   ⟹   XP_021106320
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249041,598,422 - 1,603,494 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021106317   ⟸   XM_021250658
- Peptide Label: isoform X1
RefSeq Acc Id: XP_012923930   ⟸   XM_013068476
- Peptide Label: isoform X2
- UniProtKB: G5BIF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106319   ⟸   XM_021250660
- Peptide Label: isoform X4
RefSeq Acc Id: XP_021106320   ⟸   XM_021250661
- Peptide Label: isoform X5
RefSeq Acc Id: XP_021106318   ⟸   XM_021250659
- Peptide Label: isoform X3
RefSeq Acc Id: ENSHGLP00000001683   ⟸   ENSHGLT00000001728
RefSeq Acc Id: ENSHGLP00000001684   ⟸   ENSHGLT00000001729


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001284 Ensembl, ENTREZGENE
  ENSHGLG00100011274 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000001728 ENTREZGENE
  ENSHGLT00000001729 ENTREZGENE
  ENSHGLT00100015406 UniProtKB/TrEMBL
Gene3D-CATH 3.30.160.20 UniProtKB/TrEMBL
InterPro dsRBD_dom UniProtKB/TrEMBL
  TRBP2 UniProtKB/TrEMBL
  TRBP2_DSRM_1 UniProtKB/TrEMBL
  TRBP2_DSRM_2 UniProtKB/TrEMBL
  TRBP2_DSRM_3 UniProtKB/TrEMBL
KEGG Report hgl:101701286 UniProtKB/TrEMBL
NCBI Gene Tarbp2 ENTREZGENE
PANTHER LOQUACIOUS, ISOFORM B UniProtKB/TrEMBL
  PTHR46205:SF1 UniProtKB/TrEMBL
Pfam dsrm UniProtKB/TrEMBL
PROSITE DS_RBD UniProtKB/TrEMBL
SMART DSRM UniProtKB/TrEMBL
Superfamily-SCOP dsRNA-binding domain-like UniProtKB/TrEMBL
UniProt G5BIF3 ENTREZGENE, UniProtKB/TrEMBL