Tasl (TLR adaptor interacting with endolysosomal SLC15A4) - Rat Genome Database

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Gene: Tasl (TLR adaptor interacting with endolysosomal SLC15A4) Heterocephalus glaber
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Symbol: Tasl
Name: TLR adaptor interacting with endolysosomal SLC15A4 (Ensembl:chromosome unknown CXorf21 homolog)
RGD ID: 18904599
Description: INVOLVED IN positive regulation of innate immune response (inferred); positive regulation of toll-like receptor 7 signaling pathway (inferred); positive regulation of toll-like receptor 8 signaling pathway (inferred); ASSOCIATED WITH autistic disorder (ortholog); Duchenne muscular dystrophy (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN endolysosome membrane (inferred); intracellular membrane-bounded organelle (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: chromosome unknown CXorf21 homolog; CUNHXorf21; uncharacterized protein CXorf21; uncharacterized protein CXorf21 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476225,430,926 - 25,448,114 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476225,427,519 - 25,448,180 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tasl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476225,430,926 - 25,448,114 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476225,427,519 - 25,448,180 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TASL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X30,558,809 - 30,577,766 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX30,558,809 - 30,577,766 (-)EnsemblGRCh38hg38GRCh38
GRCh37X30,576,926 - 30,595,883 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X30,486,862 - 30,505,835 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X30,336,597 - 30,355,571NCBI
CeleraX34,698,462 - 34,717,597 (-)NCBICelera
Cytogenetic MapXp21.2NCBI
HuRefX28,314,203 - 28,333,300 (-)NCBIHuRef
CHM1_1X30,607,829 - 30,626,921 (-)NCBICHM1_1
T2T-CHM13v2.0X30,150,830 - 30,169,806 (-)NCBIT2T-CHM13v2.0
Tasl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X84,820,445 - 84,935,105 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX84,913,960 - 84,935,105 (+)EnsemblGRCm39 Ensembl
GRCm38X85,776,968 - 85,891,499 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX85,870,354 - 85,891,499 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X83,115,612 - 83,136,838 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X82,122,992 - 82,144,218 (+)NCBIMGSCv36mm8
CeleraX77,064,940 - 77,086,117 (+)NCBICelera
Cytogenetic MapXC1NCBI
cM MapX39.39NCBI
Tasl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X54,354,755 - 54,373,930 (+)NCBIGRCr8
mRatBN7.2X50,403,962 - 50,423,141 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX50,361,248 - 50,423,269 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX51,733,739 - 51,752,906 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X55,234,110 - 55,253,281 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X52,865,125 - 52,884,294 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X54,390,733 - 54,409,466 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX54,390,733 - 54,409,466 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X54,590,577 - 54,609,310 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X72,641,314 - 72,660,592 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX50,943,855 - 50,963,014 (+)NCBICelera
Cytogenetic MapXq21NCBI
Tasl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955531267,216 - 293,127 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955531207,614 - 293,127 (+)NCBIChiLan1.0ChiLan1.0
TASL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X32,351,736 - 32,372,522 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X32,355,112 - 32,375,901 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X23,159,321 - 23,178,192 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X30,716,157 - 30,735,059 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX30,716,617 - 30,717,522 (-)Ensemblpanpan1.1panPan2
TASL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X25,664,361 - 25,679,044 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX30,639,199 - 30,653,660 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X25,695,592 - 25,710,287 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X25,741,501 - 25,755,942 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X25,732,975 - 25,747,432 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X25,829,165 - 25,843,624 (-)NCBIUU_Cfam_GSD_1.0
Tasl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X18,534,520 - 18,554,443 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365536,628,131 - 6,629,027 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365536,628,131 - 6,629,027 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TASL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX26,365,027 - 26,384,760 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X26,363,808 - 26,384,933 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X28,635,141 - 28,651,261 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TASL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X28,953,805 - 28,973,055 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX28,954,266 - 28,955,171 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605630,933,802 - 30,953,001 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000011164   ⟹   ENSHGLP00000011040
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476225,430,926 - 25,448,114 (+)Ensembl
RefSeq Acc Id: XM_004850060   ⟹   XP_004850117
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476225,427,519 - 25,448,180 (+)NCBI
RefSeq Acc Id: XM_021262608   ⟹   XP_021118267
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476225,427,519 - 25,448,180 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004850117 (Get FASTA)   NCBI Sequence Viewer  
  XP_021118267 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB05479 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000011040
  ENSHGLP00100000262
  ENSHGLP00100032297
  ENSHGLP00100041694
  ENSHGLP00100053571
  ENSHGLP00100057015
GenBank Protein JAO01840 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021118267   ⟸   XM_021262608
- Peptide Label: isoform X1
- UniProtKB: A0A0P6K6Z7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004850117   ⟸   XM_004850060
- Peptide Label: isoform X2
- UniProtKB: G5B868 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000011040   ⟸   ENSHGLT00000011164


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007921 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100000226 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000011164 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLT00100000289 UniProtKB/TrEMBL
  ENSHGLT00100043267 UniProtKB/TrEMBL
  ENSHGLT00100065187 UniProtKB/TrEMBL
  ENSHGLT00100072952 UniProtKB/TrEMBL
  ENSHGLT00100083595 UniProtKB/TrEMBL
InterPro TASL UniProtKB/TrEMBL
KEGG Report hgl:101720186 UniProtKB/TrEMBL
NCBI Gene CUNHXorf21 ENTREZGENE
PANTHER PTHR14889 UniProtKB/TrEMBL
  TLR ADAPTER INTERACTING WITH SLC15A4 ON THE LYSOSOME UniProtKB/TrEMBL
Pfam DUF4569 UniProtKB/TrEMBL
UniProt A0A0P6K6Z7 ENTREZGENE, UniProtKB/TrEMBL
  G5B868 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-07-14 Tasl  TLR adaptor interacting with endolysosomal SLC15A4  CUNHXorf21  chromosome unknown CXorf21 homolog  Symbol and/or name change 5135510 APPROVED