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NMN zwitterion - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:NMN zwitterion
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Accession:CHEBI:16171 term browser browse the term
Definition:A nicotinamide mononucleotide that has formula C11H15N2O8P.
Synonyms:exact_synonym: 3-carbamoyl-1-[5-O-(hydroxyphosphinato)-beta-D-ribofuranosyl]pyridinium
 related_synonym: 3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium;   3-(aminocarbonyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium, inner salt;   Formula=C11H15N2O8P;   InChI=1S/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/t7-,8-,9-,11-/m1/s1;   InChIKey=DAYLJWODMCOQEW-TURQNECASA-N;   NMN;   Nicotinamide D-ribonucleotide;   Nicotinamide mononucleotide;   Nicotinamide nucleotide;   Nicotinamide ribonucleotide;   SMILES=NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H]1O;   beta-Nicotinamide D-ribonucleotide;   beta-Nicotinamide mononucleotide;   beta-Nicotinamide ribonucleotide
 alt_id: CHEBI:10433;   CHEBI:12397;   CHEBI:13409;   CHEBI:14646;   CHEBI:14647;   CHEBI:22850;   CHEBI:25522;   CHEBI:7557
 xref: Beilstein:3570187;   CAS:1094-61-7;   KEGG:C00455;   KNApSAcK:C00019694
 xref_mesh: MESH:D009537
 xref: PDBeChem:NMN
 cyclic_relationship: is_conjugate_acid_of CHEBI:14649;   is_conjugate_base_of CHEBI:14648

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NMN zwitterion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of ACADM mRNA] CTD PMID:23834033 NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions EXP Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of ACP5 protein] CTD PMID:30292833 NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Nicotinamide Mononucleotide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:34752167 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in decreased expression of ALDOA protein] CTD PMID:38159578 NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Axin1 axin 1 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide results in increased expression of AXIN1 protein] CTD PMID:32005247 NCBI chr10:15,667,894...15,720,092
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions EXP
ISO		 Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in decreased activity of BGLAP protein]; Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in decreased expression of BGLAP protein] CTD PMID:30292833 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO
EXP		 Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of CASP1 protein modified form] CTD PMID:30292833 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Cat catalase multiple interactions ISO [Nicotinamide Mononucleotide co-treated with Zearalenone] results in decreased expression of CAT protein CTD PMID:38159578 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO Nicotinamide Mononucleotide affects the reaction [NAMPT protein affects the expression of CCND1 protein]; Nicotinamide Mononucleotide inhibits the reaction [N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide results in decreased expression of CCND1 protein] CTD PMID:32005247 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cd36 CD36 molecule multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of CD36 mRNA] CTD PMID:38159578 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd38 CD38 molecule multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of CD38 mRNA] CTD PMID:38159578 NCBI chr14:71,384,532...71,424,794
Ensembl chr14:67,172,063...67,211,986 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Nicotinamide Mononucleotide inhibits the reaction [Hydrogen Peroxide results in increased expression of CDKN1A protein]]; Dicumarol inhibits the reaction [Nicotinamide Mononucleotide inhibits the reaction [Hydrogen Peroxide results in increased expression of CDKN1A protein]]; Nicotinamide Mononucleotide inhibits the reaction [Hydrogen Peroxide results in increased expression of CDKN1A protein] CTD PMID:37640247 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions ISO 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Nicotinamide Mononucleotide inhibits the reaction [Hydrogen Peroxide results in increased expression of CDKN2A protein]]; Dicumarol inhibits the reaction [Nicotinamide Mononucleotide inhibits the reaction [Hydrogen Peroxide results in increased expression of CDKN2A protein]]; Nicotinamide Mononucleotide inhibits the reaction [Hydrogen Peroxide results in increased expression of CDKN2A protein] CTD PMID:37640247 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:34752167 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of CPT1A mRNA] CTD PMID:38159578 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO Nicotinamide Mononucleotide affects the reaction [NAMPT protein affects the expression of CTNNB1 protein]; Nicotinamide Mononucleotide inhibits the reaction [N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide results in decreased expression of CTNNB1 protein] CTD PMID:32005247 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of DGAT1 mRNA] CTD PMID:38159578 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of DGAT2 mRNA] CTD PMID:38159578 NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of ELOVL3 mRNA] CTD PMID:38159578 NCBI chr 1:254,938,731...254,942,559
Ensembl chr 1:244,997,287...245,001,115 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor decreases abundance ISO ERCC6 gene mutant form results in decreased abundance of Nicotinamide Mononucleotide CTD PMID:25440059 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of FASN mRNA] CTD PMID:38159578 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Foxo4 forkhead box O4 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of FOXO4 mRNA] CTD PMID:36336710 NCBI chr  X:70,425,218...70,432,120
Ensembl chr  X:66,385,558...66,392,115 		JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 increases expression ISO Nicotinamide Mononucleotide results in increased expression of GALNT1 mRNA CTD PMID:29935245 NCBI chr18:15,763,697...15,843,598
Ensembl chr18:15,489,020...15,568,245 		JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions ISO [resveratrol co-treated with Nicotinamide Mononucleotide] inhibits the reaction [RETN protein results in increased activity of GLB1 protein] CTD PMID:23827175 NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:114,085,508...114,158,127 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein] CTD PMID:34752167 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of H2AX protein] CTD PMID:36756972 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO
EXP		 Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of IL18 protein]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of IL18 mRNA] CTD PMID:30292833 PMID:38159578 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP		 Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of IL1B protein]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of IL1B mRNA] CTD PMID:30292833 PMID:38159578 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Lpin1 lipin 1 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of LPIN1 protein] CTD PMID:38159578 NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:39,312,748...39,417,097 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased phosphorylation of MAPK1 protein] CTD PMID:38159578 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased phosphorylation of MAPK3 protein] CTD PMID:38159578 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mir34a microRNA 34a multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA inhibits the reaction [NAMPT protein results in increased chemical synthesis of NAD]]; Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased abundance of NAD]; Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of ACADM mRNA]; Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of PPARA mRNA]; Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of PPARD mRNA] CTD PMID:23834033 NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase affects binding
multiple interactions		 EXP
ISO		 NAMPT protein binds to Nicotinamide Mononucleotide
Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA inhibits the reaction [NAMPT protein results in increased chemical synthesis of NAD]]
Nicotinamide Mononucleotide affects the reaction [NAMPT protein affects the expression of CCND1 protein]; Nicotinamide Mononucleotide affects the reaction [NAMPT protein affects the expression of CTNNB1 protein]		 CTD PMID:16901503 PMID:23834033 PMID:32005247 NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO
EXP		 Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 protein]
Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 mRNA]; Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 protein]		 CTD PMID:30292833 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase multiple interactions ISO 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in increased expression of SQSTM1 protein]]; Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of FOXO4 mRNA]; Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of PPARGC1A mRNA]; Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of SHANK2 mRNA]; Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in increased expression of SQSTM1 protein] CTD PMID:36336710 NCBI chr 2:53,144,157...53,237,857
Ensembl chr 2:51,411,413...51,504,823 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions		 ISO Nicotinamide Mononucleotide results in increased expression of NQO1 protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Nicotinamide Mononucleotide results in increased expression of NQO1 protein]		 CTD PMID:37640247 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 affects abundance
multiple interactions		 ISO PARP1 protein affects the abundance of Nicotinamide Mononucleotide
[Nicotinamide Mononucleotide co-treated with Cisplatin] results in decreased expression of PARP1 protein; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of PARP1 mRNA]		 CTD PMID:19426698 PMID:34089817 PMID:38159578 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in decreased expression of PGK1 protein] CTD PMID:38159578 NCBI chr  X:75,336,988...75,352,962
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of PNPLA2 protein] CTD PMID:38159578 NCBI chr 1:205,982,279...205,987,361
Ensembl chr 1:196,552,723...196,557,805 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of PPARA mRNA] CTD PMID:23834033 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [MIR34A mRNA results in decreased expression of PPARD mRNA]; Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of PPARD mRNA] CTD PMID:23834033 PMID:38159578 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of PPARG mRNA] CTD PMID:38159578 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of PPARGC1A mRNA] CTD PMID:36336710 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions EXP Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of PYCARD protein] CTD PMID:30292833 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Retn resistin multiple interactions ISO [resveratrol co-treated with Nicotinamide Mononucleotide] inhibits the reaction [RETN protein results in increased activity of GLB1 protein] CTD PMID:23827175 NCBI chr12:6,508,653...6,511,115
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of SCD1 mRNA] CTD PMID:38159578 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in decreased expression of SHANK2 mRNA] CTD PMID:36336710 NCBI chr 1:208,575,144...209,020,300
Ensembl chr 1:199,169,429...199,589,394 		JBrowse link
G Sirt1 sirtuin 1 increases expression
multiple interactions		 EXP
ISO		 Nicotinamide Mononucleotide results in increased expression of SIRT1 mRNA
Nicotinamide Mononucleotide inhibits the reaction [Ethanol results in decreased expression of SIRT1 mRNA]; Nicotinamide Mononucleotide inhibits the reaction [Ethanol results in decreased expression of SIRT1 protein]
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of SIRT1 mRNA]		 CTD PMID:32087266 PMID:38159578 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc12a8 solute carrier family 12, member 8 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in decreased expression of SLC12A8 mRNA] CTD PMID:38159578 NCBI chr11:80,622,000...80,771,674
Ensembl chr11:67,116,877...67,266,834 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,490,262...46,532,954
Ensembl chr10:45,991,095...46,033,904 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in decreased expression of SOD1 protein] CTD PMID:38159578 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [Nicotinamide Mononucleotide co-treated with Zearalenone] results in decreased expression of SOD2 mRNA CTD PMID:38159578 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in increased expression of SQSTM1 protein]]; Nicotinamide Mononucleotide inhibits the reaction [[NNT protein inhibits the reaction [NNT protein modified form results in decreased susceptibility to Cisplatin]] which results in increased expression of SQSTM1 protein] CTD PMID:36336710 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]; Nicotinamide Mononucleotide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Nicotinamide Mononucleotide inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:34752167 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of TNF mRNA] CTD PMID:38159578 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Txnip thioredoxin interacting protein multiple interactions ISO
EXP		 Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of TXNIP protein]
Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of TXNIP mRNA]; Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of TXNIP protein]		 CTD PMID:30292833 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions EXP
ISO		 Nicotinamide Mononucleotide inhibits the reaction [Ethanol results in increased expression of UCP2 protein]
Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of UCP2 mRNA]		 CTD PMID:32087266 PMID:38159578 NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      biological role 19856
        biochemical role 19566
          metabolite 19554
            prokaryotic metabolite 18592
              bacterial metabolite 18592
                Escherichia coli metabolite 18503
                  NMN zwitterion 58
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      chalcogen 19580
                        oxygen atom 19551
                          oxygen molecular entity 19551
                            hydroxides 19361
                              oxoacid 18797
                                pnictogen oxoacid 15018
                                  phosphorus oxoacid 14577
                                    phosphoric acids 13927
                                      phosphoric acid 13927
                                        phosphoric acid derivative 13839
                                          phosphate 13838
                                            organic phosphate 13838
                                              carbohydrate phosphate 1969
                                                phospho sugar 1814
                                                  aldose phosphate 1811
                                                    aldopentose phosphate 1803
                                                      ribose phosphate 1798
                                                        ribonucleotide 1758
                                                          nicotinamide mononucleotide 58
                                                            NMN zwitterion 58
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