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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of glial cell differentiation
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Accession:GO:0045687 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of glia cell differentiation.
Synonyms:exact_synonym: positive regulation of glia cell differentiation;   positive regulation of neuroglia differentiation;   up regulation of glial cell differentiation;   upregulation of glial cell differentiation
 narrow_synonym: activation of glial cell differentiation;   stimulation of glial cell differentiation


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positive regulation of glial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hes1 hes family bHLH transcription factor 1 IMP RGD PMID:10839357 RGD:704354 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Il1b interleukin 1 beta IDA RGD PMID:23168994 RGD:7175538 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Notch1 notch receptor 1 IMP RGD PMID:12853432 RGD:1358543 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Ntf3 neurotrophin 3 IDA RGD PMID:15139015 RGD:1358328 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596 		JBrowse link
G Rnf112 ring finger protein 112 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21566658)		 Ensembl
RGD		 PMID:21566658 GO_REF:0000107 NCBI chr10:46,121,146...46,126,691
Ensembl chr10:46,121,148...46,126,699 		JBrowse link
G Rtn4 reticulon 4 IDA RGD PMID:19379790 RGD:2314929 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Spint1 serine peptidase inhibitor, Kunitz type 1 IMP RGD PMID:23409135 RGD:10043095 NCBI chr 3:106,231,082...106,244,121
Ensembl chr 3:106,231,444...106,244,119 		JBrowse link
positive regulation of astrocyte activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1r colony stimulating factor 1 receptor IMP RGD PMID:33841088 RGD:151665762 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
positive regulation of astrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 IMP RGD PMID:23843614 RGD:8553949 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Bin1 bridging integrator 1 involved_in ISO
ISS
IEA		 (PMID:10412034)
GO_REF:0000024
GO_REF:0000107		 RGD
Alzheimers_University_of_Toronto
Ensembl		 PMID:10412034 GO_REF:0000024 GO_REF:0000107 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:99414 (PMID:10486560), (PMID:15882580)		 Ensembl
RGD		 PMID:10486560 PMID:15882580 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in ISO (MGI:5009184|PMID:12090754) RGD PMID:12090754 MGI:5009184 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:2655020|PMID:12666205)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:12666205 GO_REF:0000024 GO_REF:0000107 MGI:2655020 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:3830733 (PMID:19109490) RGD PMID:19109490 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Il1b interleukin 1 beta IDA RGD PMID:22270046 RGD:6482669 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer acts_upstream_of_or_within ISO (PMID:10486560) RGD PMID:10486560 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Lif LIF, interleukin 6 family cytokine acts_upstream_of_or_within ISO (PMID:10486560) RGD PMID:10486560 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Mag myelin-associated glycoprotein IDA RGD PMID:19349915 RGD:9685287 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656 		JBrowse link
G Notch1 notch receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2655020|PMID:12666205)		 UniProt
RGD		 PMID:12666205 GO_REF:0000024 MGI:2655020 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 IMP RGD PMID:23769735 RGD:10045891 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IEA		 (PMID:1691280)
GO_REF:0000107		 RGD
Ensembl		 PMID:1691280 GO_REF:0000107 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:10357934)		 Ensembl
RGD		 PMID:10357934 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
positive regulation of microglia differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6192878|PMID:29909984)		 UniProt
RGD		 PMID:29909984 GO_REF:0000024 MGI:6192878 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
positive regulation of oligodendrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspa aspartoacylase IMP RGD PMID:16634055 RGD:1599295 NCBI chr10:57,891,704...57,945,267
Ensembl chr10:57,892,104...57,945,272 		JBrowse link
G Clcn2 chloride voltage-gated channel 2 IMP RGD PMID:29344669 RGD:213230158 NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 involved_in ISO (MGI:4458974|PMID:20534485) RGD PMID:20534485 MGI:4458974 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Dag1 dystroglycan 1 IMP RGD PMID:17395644 RGD:11541054 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 IDA RGD PMID:22139091 RGD:9685417 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Gsx2 GS homeobox 2 acts_upstream_of_or_within ISO (PMID:23042297) RGD PMID:23042297 NCBI chr14:33,123,799...33,126,151
Ensembl chr14:33,124,381...33,126,105 		JBrowse link
G Hdac1 histone deacetylase 1 acts_upstream_of_or_within IMP
ISO		 MGI:1097691 (PMID:19503085) RGD PMID:19503085 PMID:22573687 RGD:9590148 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within IMP
ISO		 MGI:108086 (PMID:19503085) RGD PMID:19503085 PMID:22573687 RGD:9590148 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Il33 interleukin 33 IMP RGD PMID:31165473 RGD:40400907 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il34 interleukin 34 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5805301|PMID:27445335)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:27445335 GO_REF:0000024 GO_REF:0000107 MGI:5805301 NCBI chr19:38,714,990...38,782,749
Ensembl chr19:38,714,991...38,764,000 		JBrowse link
G Mdk midkine involved_in ISO
IEA
ISS		 (PMID:27445335)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:27445335 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Mir219a1 microRNA 219a-1 acts_upstream_of_or_within ISO (PMID:20223197) RGD PMID:20223197 NCBI chr20:4,829,687...4,829,796
Ensembl chr20:4,829,687...4,829,796 		JBrowse link
G Mir23a microRNA 23a acts_upstream_of_or_within ISO (PMID:24101522) RGD PMID:24101522 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071 		JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within
involved_in		 IMP
ISO
IEA		 MGI:2179311|MGI:3850506 (PMID:25411504)
GO_REF:0000107		 RGD
Ensembl		 PMID:25411504 PMID:19439614 GO_REF:0000107, RGD:10040963 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myrf myelin regulatory factor IDA RGD PMID:27370227 RGD:213230157 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO MGI:1355331 (PMID:11566099) RGD PMID:11566099 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Nkx6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO MGI:1352738 (PMID:15629702) RGD PMID:15629702 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681 		JBrowse link
G Nkx6-2 NK6 homeobox 2 acts_upstream_of_or_within ISO MGI:1206039 (PMID:15629702) RGD PMID:15629702 NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515 		JBrowse link
G Olig2 oligodendrocyte transcription factor 2 acts_upstream_of_or_within ISO MGI:97347 (PMID:11566099) RGD PMID:11566099 NCBI chr11:30,475,510...30,478,886
Ensembl chr11:30,475,398...30,480,152 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IMP RGD PMID:18543250 RGD:2301878 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prmt5 protein arginine methyltransferase 5 IMP RGD PMID:22041901 RGD:9491827 NCBI chr15:27,968,893...27,978,291
Ensembl chr15:27,968,910...27,978,296 		JBrowse link
G Ptn pleiotrophin involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27445335), (PMID:30667096)		 UniProt
Ensembl
RGD		 PMID:27445335 PMID:30667096 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456 		JBrowse link
G Ptpra protein tyrosine phosphatase, receptor type, A IMP RGD PMID:19812040 RGD:2314625 NCBI chr 3:117,650,146...117,759,744
Ensembl chr 3:117,650,183...117,759,728 		JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 involved_in IMP PMID:30667096 UniProt PMID:30667096 RGD:14397553 NCBI chr 4:51,397,316...51,595,220
Ensembl chr 4:51,397,601...51,595,218 		JBrowse link
G Qki QKI, KH domain containing RNA binding involved_in IMP
ISO
IEA		 (MGI:4839851|PMID:20956316), (MGI:4950003|PMID:21253564), (MGI:5903342|PMID:28188285)
GO_REF:0000107		 RGD
Ensembl		 PMID:20956316 PMID:21253564 PMID:28188285 PMID:17575274 GO_REF:0000107 MGI:4839851 MGI:4950003 MGI:5903342, RGD:10045992 NCBI chr 1:50,387,716...50,501,568
Ensembl chr 1:50,387,698...50,498,831 		JBrowse link
G Rheb Ras homolog, mTORC1 binding involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2179311|MGI:3850507 (PMID:25411504)		 Ensembl
RGD		 PMID:25411504 GO_REF:0000107 NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:11171336)		 Ensembl
RGD		 PMID:11171336 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Tenm4 teneurin transmembrane protein 4 involved_in ISO (MGI:5437806|PMID:22915103) RGD PMID:22915103 MGI:5437806 NCBI chr 1:149,895,097...151,263,315
Ensembl chr 1:150,780,381...151,259,144 		JBrowse link
G Tlr2 toll-like receptor 2 IDA RGD PMID:21971760 RGD:7241097 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO
IBA		 (MGI:5775216|PMID:27147664)
GO_REF:0000033		 RGD
GO_Central		 PMID:27147664 GO_REF:0000033 MGI:5775216 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tp73 tumor protein p73 IMP RGD PMID:14960496 RGD:2291843 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Zfp365 zinc finger protein 365 involved_in IMP
IEA
ISO		 PMID:24481677
GO_REF:0000107
(MGI:5558972|PMID:24481677)		 Ensembl
RGD		 PMID:24481677 PMID:24481677 GO_REF:0000107 MGI:5558972, RGD:13210567 NCBI chr20:20,666,240...20,689,734
Ensembl chr20:20,666,240...20,691,238 		JBrowse link
G Zfp488 zinc finger protein 488 involved_in
acts_upstream_of_or_within		 ISO (MGI:6189284|PMID:22355521)
MGI:1355331 (PMID:16908628)		 RGD PMID:16908628 PMID:22355521 MGI:6189284 NCBI chr16:9,283,039...9,293,681
Ensembl chr16:9,283,043...9,293,671 		JBrowse link
positive regulation of Schwann cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag1 BAG cochaperone 1 IMP RGD PMID:23108487 RGD:13506903 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075 		JBrowse link
G Dicer1 dicer 1 ribonuclease III involved_in ISO (MGI:4454581|PMID:20463238), (MGI:4830414|PMID:20805985) RGD PMID:20463238 PMID:20805985 MGI:4454581 MGI:4830414 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Egr2 early growth response 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:1331140|PMID:10068633)		 UniProt
RGD		 PMID:10068633 GO_REF:0000024 MGI:1331140 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IMP RGD PMID:18385332 RGD:2298785 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18195
      cellular developmental process 4695
        cell differentiation 4694
          glial cell differentiation 325
            positive regulation of glial cell differentiation 56
              positive regulation of Schwann cell differentiation 4
              positive regulation of astrocyte differentiation + 15
              positive regulation of microglia differentiation 1
              positive regulation of oligodendrocyte differentiation 33
Path 2
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      anatomical structure development 6486
        multicellular organism development 5239
          system development 4526
            nervous system development 2801
              neurogenesis 2065
                gliogenesis 441
                  glial cell differentiation 325
                    regulation of glial cell differentiation 97
                      positive regulation of glial cell differentiation 56
                        positive regulation of Schwann cell differentiation 4
                        positive regulation of astrocyte differentiation + 15
                        positive regulation of microglia differentiation 1
                        positive regulation of oligodendrocyte differentiation 33
paths to the root