Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of interleukin-1 beta production
go back to main search page
Accession:GO:0032731 term browser browse the term
Definition:Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production.
Synonyms:exact_synonym: positive regulation of IL-1 beta production;   up regulation of interleukin-1 beta production;   upregulation of interleukin-1 beta production
 narrow_synonym: activation of interleukin-1 beta production;   positive regulation of interleukin-1 beta biosynthetic process;   positive regulation of interleukin-1 beta secretion;   stimulation of interleukin-1 beta production
 alt_id: GO:0050718;   GO:0050725


show annotations for term's descendants           Sort by:
positive regulation of interleukin-1 beta production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P05067 (PMID:22406537)		 Ensembl
RGD		 PMID:22406537 GO_REF:0000107 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Aim2 absent in melanoma 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:19158675), (PMID:19158676), (PMID:19158679), (PMID:24630722)
MGI:2653833 (PMID:23997220)
(PMID:19158675), (PMID:19158676), (PMID:34006824)		 RGD PMID:19158675 PMID:19158676 PMID:19158679 PMID:23997220 PMID:24630722 More... NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975 		JBrowse link
G App amyloid beta precursor protein involved_in ISO
IEA		 UniProtKB:Q62151 (PMID:22406537)
GO_REF:0000107		 RGD
Ensembl		 PMID:22406537 GO_REF:0000107 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Casp1 caspase 1 involved_in
acts_upstream_of_or_within		 IMP
IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:18490713)
(PMID:11432859), (PMID:11536016), (PMID:11821383), (PMID:15030775), (PMID:15326478), (PMID:16037825), (PMID:22267217), (PMID:24630722), (PMID:7642516)
(PMID:21147462), (PMID:27270401), (PMID:29255148)		 Ensembl
UniProt
RGD		 PMID:7642516 PMID:11432859 PMID:11536016 PMID:11821383 PMID:15030775 More... GO_REF:0000024 GO_REF:0000107, RGD:2315918 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp4 caspase 4 acts_upstream_of_or_within ISO MGI:1931465|MGI:2653833 (PMID:22002608) RGD PMID:22002608 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp8 caspase 8 involved_in ISO (PMID:22267217) RGD PMID:22267217 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15845453) RGD PMID:15845453 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:P22893 (PMID:21784977)		 UniProt
RGD		 PMID:21784977 GO_REF:0000024 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccn1 cellular communication network factor 1 IMP RGD PMID:27653023 RGD:150429754 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 IMP RGD PMID:16790532 RGD:1598562 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Cd36 CD36 molecule involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23812099)		 UniProt
Ensembl
RGD		 PMID:23812099 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:22267217) RGD PMID:22267217 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Egr1 early growth response 1 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:11100120)		 Ensembl
UniProt
RGD		 PMID:11100120 GO_REF:0000024 GO_REF:0000107 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15155775)		 UniProt
RGD		 PMID:15155775 GO_REF:0000024 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fzd5 frizzled class receptor 5 involved_in IEA
ISO		 GO_REF:0000107
ComplexPortal:CPX-1134|UniProtKB:P22725 (PMID:21857966)		 Ensembl
RGD		 PMID:21857966 GO_REF:0000107 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:22461501) RGD PMID:22461501 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
G Gsdmd gasdermin D involved_in ISO (PMID:26611636), (PMID:29195811), (PMID:29274245), (PMID:33883744) RGD PMID:26611636 PMID:29195811 PMID:29274245 PMID:33883744 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055 		JBrowse link
G Hk1 hexokinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:27374331)		 Ensembl
RGD		 PMID:27374331 GO_REF:0000107 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:19890330) RGD PMID:19890330 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12385642)		 Ensembl
RGD		 PMID:12385642 GO_REF:0000107 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 acts_upstream_of_or_within ISO (PMID:23997220) RGD PMID:23997220 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within
involved_in		 ISO MGI:1857184 (PMID:12925700)
(PMID:26227742)		 RGD PMID:12925700 PMID:26227742 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il17a interleukin 17A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:29734196)
GO_REF:0000107		 RGD
Ensembl		 PMID:29734196 GO_REF:0000107 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il18 interleukin 18 IEP RGD PMID:17623049 RGD:4889480 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il6 interleukin 6 involved_in ISO RNAcentral:URS00004E0808_9606 (PMID:31886314) RGD PMID:31886314 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Isl1 ISL LIM homeobox 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22727192)		 Ensembl
RGD		 PMID:22727192 GO_REF:0000107 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Jak2 Janus kinase 2 involved_in IMP
ISO		 during cerulein-induced pancreatitis
UniProtKB:P01580 (PMID:26227742)		 RGD PMID:26227742 PMID:16934228 RGD:1641810 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Lilra5 leukocyte immunoglobulin like receptor A5 involved_in ISO (PMID:12393390), (PMID:19009525) RGD PMID:12393390 PMID:19009525 NCBI chr 1:69,973,292...69,978,750
Ensembl chr 1:69,973,292...70,001,718 		JBrowse link
G Lpl lipoprotein lipase involved_in IEA
ISO		 GO_REF:0000107
RNAcentral:URS00005C83FD_10090 (PMID:22963823)		 Ensembl
RGD		 PMID:22963823 GO_REF:0000107 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Malt1 MALT1 paracaspase involved_in ISO (PMID:22267217) RGD PMID:22267217 NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260 		JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISO (PMID:16037825)
(PMID:27270401)		 RGD PMID:16037825 PMID:27270401 NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973 		JBrowse link
G Mir144 microRNA 144 involved_in ISO (PMID:24733347) RGD PMID:24733347 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
G Mir206 microRNA 206 involved_in ISO (PMID:27277332) RGD PMID:27277332 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332 		JBrowse link
G Mir23a microRNA 23a IMP RGD PMID:33403590 RGD:155882539 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in ISS
ISO		 GO_REF:0000024
(PMID:33718825)		 UniProt
RGD		 PMID:33718825 GO_REF:0000024 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISO
ISS		 UniProtKB:P10749|UniProtKB:P29466 (PMID:15882992)
GO_REF:0000024
(PMID:16648852), (PMID:16648853), (PMID:22484733)		 RGD
UniProt		 PMID:15882992 PMID:16648852 PMID:16648853 PMID:22484733 GO_REF:0000024 NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A involved_in ISO (PMID:33243852), (PMID:7642516)
(PMID:18511561)		 RGD PMID:7642516 PMID:18511561 PMID:33243852 NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180 		JBrowse link
G Nlrp2 NLR family pyrin domain containing 2 involved_in ISO (PMID:15030775) RGD PMID:15030775 NCBI chr 1:69,515,505...69,554,689
Ensembl chr 1:69,515,505...69,554,454 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:15030775), (PMID:16407889), (PMID:17483456), (PMID:18403674), (PMID:18604214), (PMID:23582325), (PMID:25686105), (PMID:28847925), (PMID:30487600), (PMID:31086327), (PMID:31086329), (PMID:31189953)
MGI:107700|MGI:1931465|MGI:2686159 (PMID:22002608), (PMID:23997220)
(PMID:23582325), (PMID:27374331), (PMID:28847925), (PMID:29255148), (PMID:30487600)		 UniProt
RGD		 PMID:15030775 PMID:16407889 PMID:17483456 PMID:18403674 PMID:18604214 More... GO_REF:0000024 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 IMP RGD PMID:22450316 RGD:9831170 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:15107016), (PMID:21040358) RGD PMID:15107016 PMID:21040358 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Orm1 orosomucoid 1 involved_in ISO (PMID:8774350) RGD PMID:8774350 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 IDA
IMP
ISO		 (PMID:17036048), (PMID:18089587)
MGI:2386080|MGI:3606250 (PMID:11016935), (PMID:15905573), (PMID:18490713)		 RGD PMID:11016935 PMID:15905573 PMID:17036048 PMID:18089587 PMID:18490713 More... RGD:1642715, RGD:1642715 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Panx1 Pannexin 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:17036048)
(PMID:18490713)		 RGD PMID:17036048 PMID:18490713 NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774 		JBrowse link
G Pycard PYD and CARD domain containing involved_in
acts_upstream_of_or_within		 ISO (PMID:15030775), (PMID:16037825), (PMID:22267217), (PMID:24630722), (PMID:7642516)
MGI:107700|MGI:2653833|MGI:3686870 (PMID:22002608), (PMID:23997220)
(PMID:19158675), (PMID:27270401), (PMID:29255148)		 RGD PMID:7642516 PMID:15030775 PMID:16037825 PMID:19158675 PMID:22002608 More... NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit acts_upstream_of ISO (PMID:27203220) RGD PMID:27203220 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in ISO (PMID:11432859) RGD PMID:11432859 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Smad3 SMAD family member 3 IMP TGFbeta-1 dependent, in pancreatic stellate cells RGD PMID:16371439 RGD:2300404 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO
IEA		 RNAcentral:URS00004E0808_9606|UniProtKB:P05231 (PMID:31886314)
GO_REF:0000107		 RGD
Ensembl		 PMID:31886314 GO_REF:0000107 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stmp1 short transmembrane mitochondrial protein 1 involved_in ISO (PMID:31836654) RGD PMID:31836654 NCBI chr 4:63,927,523...63,937,355 JBrowse link
G Tlr2 toll-like receptor 2 involved_in ISO ComplexPortal:CPX-1134 (PMID:22198949) RGD PMID:22198949 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:11432859)
GO_REF:0000107
(PMID:23812099)		 UniProt
RGD
Ensembl		 PMID:11432859 PMID:23812099 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO (PMID:23812099) RGD PMID:23812099 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tlr8 toll-like receptor 8 involved_in ISO (PMID:24942581), (PMID:33718825) RGD PMID:24942581 PMID:33718825 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549 		JBrowse link
G Tmem106a transmembrane protein 106A involved_in ISS
ISO		 GO_REF:0000024
(PMID:26215746)		 UniProt
RGD		 PMID:26215746 GO_REF:0000024 NCBI chr10:86,506,908...86,515,915
Ensembl chr10:86,506,936...86,515,892 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:31124343) RGD PMID:31124343 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Trim16 tripartite motif-containing 16 involved_in ISO (PMID:16575408) RGD PMID:16575408 NCBI chr10:47,485,982...47,509,010
Ensembl chr10:47,486,297...47,551,907 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO (PMID:25690660) RGD PMID:25690660 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
G Usp50 ubiquitin specific peptidase 50 acts_upstream_of_or_within ISO (PMID:28094437) RGD PMID:28094437 NCBI chr 3:114,012,104...114,035,468
Ensembl chr 3:114,011,702...114,035,476 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO
IEA		 (PMID:18174455)
GO_REF:0000107
ComplexPortal:CPX-1134|UniProtKB:Q9EQD0 (PMID:18174455), (PMID:21857966)		 RGD
Ensembl		 PMID:18174455 PMID:21857966 GO_REF:0000107 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    positive regulation of biological process 6746
      positive regulation of multicellular organismal process 1895
        positive regulation of cytokine production 535
          positive regulation of interleukin-1 production 73
            positive regulation of interleukin-1 beta production 62
Path 2
Term Annotations click to browse term
  biological_process 20069
    biological regulation 13554
      regulation of biological process 13131
        regulation of cellular process 12768
          regulation of metabolic process 6743
            regulation of biosynthetic process 5507
              regulation of macromolecule biosynthetic process 5305
                regulation of gene expression 5186
                  regulation of cytokine production 906
                    regulation of interleukin-1 production 133
                      regulation of interleukin-1 beta production 111
                        positive regulation of interleukin-1 beta production 62
paths to the root