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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Salidroside
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Accession:CHEBI:9009 term browser browse the term
Definition:A glycoside that has formula C14H20O7.
Synonyms:related_synonym: Formula=C14H20O7;   InChI=1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1;   InChIKey=ILRCGYURZSFMEG-RKQHYHRCSA-N;   SMILES=OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O;   Tyrosol glucoside;   p-Hydroxyphenethyl alcohol 1-O-beta-D-glucoside
 xref: CAS:10338-51-9;   KEGG:C06046
 xref_mesh: MESH:C009172


show annotations for term's descendants           Sort by:
Salidroside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions EXP rhodioloside affects the reaction [ABCB1 protein results in increased transport of Digoxin] CTD PMID:24380838 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 multiple interactions ISO [furan co-treated with rhodioloside] results in increased expression of ABCB11 mRNA CTD PMID:32251705 NCBI chr 2:168,915,390...169,031,324
Ensembl chr 2:168,915,498...169,031,324 		JBrowse link
G ACHE acetylcholinesterase (Yt blood group) multiple interactions ISO rhodioloside inhibits the reaction [Isoflurane results in increased activity of ACHE protein] CTD PMID:28084090 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in decreased phosphorylation of AKT1 protein]]; rhodioloside inhibits the reaction [Colistin results in decreased phosphorylation of AKT1 protein] CTD PMID:28465020 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G ALPL alkaline phosphatase, biomineralization associated increases activity
increases expression		 ISO rhodioloside results in increased activity of ALPL protein
rhodioloside results in increased expression of ALPL mRNA		 CTD PMID:24055767 NCBI chr 1:21,508,984...21,578,410
Ensembl chr 1:21,509,397...21,578,410 		JBrowse link
G AOC1 amine oxidase copper containing 1 decreases secretion ISO rhodioloside results in decreased secretion of AOC1 protein CTD PMID:37530723 NCBI chr 7:150,852,120...150,861,504
Ensembl chr 7:150,824,627...150,861,504 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP		 rhodioloside inhibits the reaction [Doxorubicin results in increased expression of BAX mRNA]
rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]; sirtinol inhibits the reaction [rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in increased expression of BAX protein]]; rhodioloside inhibits the reaction [cobaltous chloride results in increased expression of BAX protein]; rhodioloside inhibits the reaction [Colistin results in increased expression of BAX protein]; rhodioloside inhibits the reaction [Doxorubicin results in increased expression of BAX mRNA]; rhodioloside inhibits the reaction [Doxorubicin results in increased expression of BAX protein]		 CTD PMID:21499890 PMID:24072175 PMID:28465020 PMID:28851138 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression
multiple interactions		 ISO
EXP		 rhodioloside results in increased expression of BCL2 mRNA
rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]; sirtinol inhibits the reaction [rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in decreased expression of BCL2 protein]]; rhodioloside inhibits the reaction [Colistin results in decreased expression of BCL2 protein]; rhodioloside inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA]
rhodioloside results in increased expression of BCL2 protein		 CTD PMID:24072175 PMID:28465020 PMID:28851138 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BMP2 bone morphogenetic protein 2 increases expression ISO rhodioloside results in increased expression of BMP2 mRNA CTD PMID:24055767 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G BMP6 bone morphogenetic protein 6 increases expression ISO rhodioloside results in increased expression of BMP6 mRNA CTD PMID:24055767 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G BMP7 bone morphogenetic protein 7 increases expression ISO rhodioloside results in increased expression of BMP7 mRNA CTD PMID:24055767 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641 		JBrowse link
G CASP1 caspase 1 multiple interactions ISO rhodioloside inhibits the reaction [Glucose results in increased expression of CASP1 protein]
rhodioloside inhibits the reaction [furan results in increased cleavage of CASP1 protein]		 CTD PMID:29031534 PMID:34450210 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP12 caspase 12 (gene/pseudogene) multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased cleavage of CASP12 protein] CTD PMID:34450210 NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO
EXP		 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in increased activity of and results in increased cleavage of CASP3 protein]]; rhodioloside inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; rhodioloside inhibits the reaction [Colistin results in increased activity of and results in increased cleavage of CASP3 protein]; rhodioloside inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]
rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; sirtinol inhibits the reaction [rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]]		 CTD PMID:24072175 PMID:28465020 PMID:28851138 PMID:30991096 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CAT catalase increases expression
multiple interactions		 ISO rhodioloside results in increased expression of CAT mRNA; rhodioloside results in increased expression of CAT protein
rhodioloside inhibits the reaction [furan results in decreased activity of CAT protein]; rhodioloside inhibits the reaction [furan results in decreased expression of CAT mRNA]; rhodioloside inhibits the reaction [Streptozocin results in decreased activity of CAT protein]		 CTD PMID:24072175 PMID:31682803 PMID:34450210 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CDH2 cadherin 2 multiple interactions ISO rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CDH2 protein] CTD PMID:31682803 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946 		JBrowse link
G CERT1 ceramide transporter 1 multiple interactions ISO rhodioloside inhibits the reaction [Glucose results in increased expression of CERT1 mRNA] CTD PMID:29031534 NCBI chr 5:75,368,486...75,511,981
Ensembl chr 5:75,356,345...75,512,138 		JBrowse link
G CHAT choline O-acetyltransferase multiple interactions ISO rhodioloside inhibits the reaction [Isoflurane results in decreased activity of CHAT protein] CTD PMID:28084090 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942 		JBrowse link
G CLDN11 claudin 11 multiple interactions ISO rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CLDN11 protein] CTD PMID:31682803 NCBI chr 3:170,418,868...170,434,691
Ensembl chr 3:170,418,868...170,454,733 		JBrowse link
G CYBB cytochrome b-245 beta chain multiple interactions EXP rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of CYBB protein]; sirtinol inhibits the reaction [rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of CYBB protein]] CTD PMID:28851138 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased expression of CYP2E1 protein] CTD PMID:34450210 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO rhodioloside inhibits the reaction [furan results in decreased expression of CYP7A1 mRNA] CTD PMID:32251705 NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased expression of DDIT3 mRNA]; rhodioloside inhibits the reaction [furan results in increased expression of DDIT3 protein] CTD PMID:34450210 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 multiple interactions ISO rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 mRNA]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 protein] CTD PMID:24989011 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G ENO2 enolase 2 multiple interactions
increases expression		 ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester promotes the reaction [rhodioloside results in increased expression of ENO2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of ENO2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of ENO2 protein]
rhodioloside results in increased expression of ENO2 mRNA; rhodioloside results in increased expression of ENO2 protein		 CTD PMID:24929042 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased phosphorylation of ERN1 protein] CTD PMID:34450210 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G FGF19 fibroblast growth factor 19 multiple interactions ISO [furan co-treated with rhodioloside] results in increased expression of FGF15 mRNA CTD PMID:32251705 NCBI chr11:69,698,238...69,704,022
Ensembl chr11:69,698,238...69,704,022 		JBrowse link
G FN1 fibronectin 1 multiple interactions ISO rhodioloside inhibits the reaction [Glucose results in increased expression of FN1 mRNA] CTD PMID:29031534 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G HES1 hes family bHLH transcription factor 1 decreases expression ISO rhodioloside results in decreased expression of HES1 mRNA CTD PMID:24929042 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions ISO [rhodioloside co-treated with cobaltous chloride co-treated with NGF protein] results in decreased expression of HIF1A mRNA; R 59949 inhibits the reaction [rhodioloside promotes the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein]]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of HIF1A protein]; rhodioloside promotes the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein] CTD PMID:21499890 PMID:24989011 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased expression of HSPA5 mRNA]; rhodioloside inhibits the reaction [furan results in increased expression of HSPA5 protein] CTD PMID:34450210 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G IL18 interleukin 18 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased expression of IL18 mRNA]; rhodioloside inhibits the reaction [furan results in increased expression of IL18 protein] CTD PMID:34450210 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO rhodioloside inhibits the reaction [Isoflurane results in increased expression of IL1B protein]
rhodioloside inhibits the reaction [furan results in increased expression of IL1B mRNA]; rhodioloside inhibits the reaction [furan results in increased expression of IL1B protein]; rhodioloside results in decreased secretion of and results in decreased expression of IL1B protein		 CTD PMID:28084090 PMID:34450210 PMID:37530723 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased expression of IL6 mRNA]; rhodioloside results in decreased secretion of and results in decreased expression of IL6 protein CTD PMID:34450210 PMID:37530723 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MAP2 microtubule associated protein 2 multiple interactions
increases expression		 ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester promotes the reaction [rhodioloside results in increased expression of MAP2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of MAP2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of MAP2 protein]
rhodioloside results in increased expression of MAP2 mRNA; rhodioloside results in increased expression of MAP2 protein		 CTD PMID:24929042 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAP3K5 protein] CTD PMID:34450210 NCBI chr 6:136,557,046...136,793,091
Ensembl chr 6:136,557,046...136,793,097 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAPK1 protein] CTD PMID:34450210 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAPK3 protein] CTD PMID:34450210 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAPK8 protein] CTD PMID:34450210 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions ISO Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein] CTD PMID:24989011 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased phosphorylation of NFKBIA protein] CTD PMID:34450210 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NGF nerve growth factor multiple interactions ISO [rhodioloside co-treated with cobaltous chloride co-treated with NGF protein] results in decreased expression of HIF1A mRNA; Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]]; Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 mRNA]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 protein]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of HIF1A protein] CTD PMID:24989011 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions ISO rhodioloside inhibits the reaction [Glucose results in increased expression of NLRP3 protein]
rhodioloside inhibits the reaction [furan results in increased expression of NLRP3 protein]		 CTD PMID:29031534 PMID:34450210 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108 		JBrowse link
G NOG noggin multiple interactions ISO NOG protein inhibits the reaction [rhodioloside results in increased expression of ENO2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of ENO2 protein]; NOG protein inhibits the reaction [rhodioloside results in increased expression of MAP2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of MAP2 protein]; NOG protein inhibits the reaction [rhodioloside results in increased expression of TUBB3 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of TUBB3 protein] CTD PMID:24929042 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611 		JBrowse link
G NOTCH1 notch receptor 1 decreases expression ISO rhodioloside results in decreased expression of NOTCH1 mRNA CTD PMID:24929042 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NOX1 NADPH oxidase 1 multiple interactions ISO rhodioloside inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA] CTD PMID:24072175 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased expression of NR0B2 mRNA] CTD PMID:32251705 NCBI chr 1:26,911,489...26,913,975
Ensembl chr 1:26,911,489...26,913,975 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 multiple interactions ISO rhodioloside affects the reaction [furan affects the expression of NR1H4 mRNA] CTD PMID:32251705 NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414 		JBrowse link
G OCLN occludin multiple interactions ISO rhodioloside affects the reaction [furan results in decreased expression of OCLN protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased expression of OCLN protein] CTD PMID:31682803 PMID:32251705 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO rhodioloside results in increased phosphorylation of [PRKAA1 protein binds to PRKAA2 protein] CTD PMID:37530723 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions ISO rhodioloside results in increased phosphorylation of [PRKAA1 protein binds to PRKAA2 protein] CTD PMID:37530723 NCBI chr 1:56,645,314...56,715,335
Ensembl chr 1:56,645,314...56,715,335 		JBrowse link
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta multiple interactions ISO rhodioloside inhibits the reaction [[Oxygen co-treated with Glucose deficiency] results in decreased expression of PRKAR2B protein] CTD PMID:24726522 NCBI chr 7:107,044,705...107,161,811
Ensembl chr 7:107,044,705...107,161,811 		JBrowse link
G PYCARD PYD and CARD domain containing multiple interactions ISO rhodioloside inhibits the reaction [Glucose results in increased expression of PYCARD protein]
rhodioloside inhibits the reaction [furan results in increased expression of PYCARD protein]		 CTD PMID:29031534 PMID:34450210 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO rhodioloside inhibits the reaction [cobaltous chloride results in increased expression of RELA protein]
rhodioloside inhibits the reaction [furan results in increased phosphorylation of RELA protein]		 CTD PMID:21499890 PMID:34450210 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 multiple interactions ISO Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:24989011 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G RUNX2 RUNX family transcription factor 2 increases expression
increases activity		 ISO rhodioloside results in increased expression of RUNX2 mRNA
rhodioloside results in increased activity of RUNX2 protein		 CTD PMID:24055767 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions EXP rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of and results in decreased activity of SIRT1 protein] CTD PMID:28851138 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SMAD1 SMAD family member 1 multiple interactions
increases expression		 ISO rhodioloside results in increased phosphorylation of and results in increased expression of SMAD1 protein
rhodioloside results in increased expression of SMAD1 mRNA		 CTD PMID:24929042 NCBI chr 4:145,480,770...145,559,176
Ensembl chr 4:145,481,194...145,559,176 		JBrowse link
G SMAD5 SMAD family member 5 increases expression
multiple interactions		 ISO rhodioloside results in increased expression of SMAD5 mRNA
rhodioloside results in increased phosphorylation of and results in increased expression of SMAD5 protein		 CTD PMID:24929042 NCBI chr 5:136,132,845...136,182,733
Ensembl chr 5:136,132,845...136,188,747 		JBrowse link
G SMAD9 SMAD family member 9 increases expression
multiple interactions		 ISO rhodioloside results in increased expression of SMAD9 mRNA
rhodioloside results in increased phosphorylation of and results in increased expression of SMAD9 protein		 CTD PMID:24929042 NCBI chr13:36,844,831...36,920,854
Ensembl chr13:36,844,831...36,920,887 		JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions ISO rhodioloside inhibits the reaction [furan results in decreased expression of SOD1 mRNA] CTD PMID:34450210 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 increases expression ISO rhodioloside results in increased expression of SOD2 mRNA; rhodioloside results in increased expression of SOD2 protein CTD PMID:24072175 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SP7 Sp7 transcription factor increases expression ISO rhodioloside results in increased expression of SP7 mRNA CTD PMID:24055767 NCBI chr12:53,326,575...53,344,793
Ensembl chr12:53,326,575...53,345,315 		JBrowse link
G SPP1 secreted phosphoprotein 1 increases expression ISO rhodioloside results in increased expression of SPP1 mRNA CTD PMID:24055767 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO rhodioloside inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; rhodioloside inhibits the reaction [Paraquat results in increased expression of TGFB1 protein] CTD PMID:25674253 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TJP1 tight junction protein 1 multiple interactions ISO rhodioloside inhibits the reaction [furan results in decreased expression of TJP1 protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased expression of TJP1 protein] CTD PMID:31682803 PMID:32251705 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO rhodioloside inhibits the reaction [Isoflurane results in increased expression of TNF protein]
rhodioloside inhibits the reaction [furan results in increased expression of TNF mRNA]; rhodioloside results in decreased secretion of and results in decreased expression of TNF protein		 CTD PMID:28084090 PMID:34450210 PMID:37530723 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TRAF2 TNF receptor associated factor 2 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased expression of TRAF2 protein] CTD PMID:34450210 NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,912...136,926,607 		JBrowse link
G TUBB3 tubulin beta 3 class III multiple interactions
increases expression		 ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester promotes the reaction [rhodioloside results in increased expression of TUBB3 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of TUBB3 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of TUBB3 protein]
rhodioloside results in increased expression of TUBB3 mRNA; rhodioloside results in increased expression of TUBB3 protein		 CTD PMID:24929042 NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761 		JBrowse link
G TXNIP thioredoxin interacting protein multiple interactions
decreases expression		 ISO rhodioloside inhibits the reaction [Glucose results in increased expression of TXNIP protein]
rhodioloside results in decreased expression of TXNIP protein		 CTD PMID:29031534 PMID:37530723 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579 		JBrowse link
G XBP1 X-box binding protein 1 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased expression of XBP1 protein] CTD PMID:34450210 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    chemical entity 26019
      atom 26015
        nonmetal atom 25503
          oxygen atom 24811
            oxygen molecular entity 24811
              organooxygen compound 24060
                carbohydrates and carbohydrate derivatives 16777
                  carbohydrate derivative 15654
                    glycosyl compound 13719
                      glycoside 12279
                        Salidroside 71
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    p-block element atom 25840
                      carbon group element atom 25437
                        carbon atom 25395
                          organic molecular entity 25395
                            heteroorganic entity 24770
                              organochalcogen compound 24383
                                organooxygen compound 24060
                                  carbohydrates and carbohydrate derivatives 16777
                                    carbohydrate 16777
                                      carbohydrate derivative 15654
                                        glycosyl compound 13719
                                          glycoside 12279
                                            Salidroside 71
paths to the root