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2-ethoxyethanol - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2-ethoxyethanol
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Accession:CHEBI:46788 term browser browse the term
Definition:A hydroxyether that is the ethyl ether derivative of ethylene glycol.
Synonyms:related_synonym: 2-ethoxyethyl alcohol;   2EE;   Cellosolve;   Formula=C4H10O2;   HOCH2CH2OC2H5;   InChI=1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3;   InChIKey=ZNQVEEAIQZEUHB-UHFFFAOYSA-N;   Oxitol;   SMILES=CCOCCO;   beta-ethoxyethanol;   ethylene glycol ethyl ether;   ethylene glycol monoethyl ether
 alt_id: CHEBI:34272;   CHEBI:42340
 xref: CAS:110-80-5;   DrugBank:DB02249;   Gmelin:82142;   HMDB:HMDB0031213;   KEGG:C14687
 xref_mesh: MESH:C021296
 xref: PDBeChem:ETX;   PMID:12209180;   PMID:24399739;   PMID:2625497;   PMID:7151721;   Reaxys:1098271;   Wikipedia:2-Ethoxyethanol

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2-ethoxyethanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt2 AKT serine/threonine kinase 2 increases expression EXP 2-ethoxyethanol results in increased expression of AKT2 mRNA CTD PMID:19643169 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 increases expression EXP 2-ethoxyethanol results in increased expression of AKT3 mRNA CTD PMID:19643169 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:88,946,091...89,225,708 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases reaction ISO ALDH2 protein promotes the reaction 2-ethoxyethanol CTD PMID:17878629 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G App amyloid beta precursor protein increases expression EXP 2-ethoxyethanol results in increased expression of APP mRNA CTD PMID:19643169 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Arf3 ARF GTPase 3 increases expression EXP 2-ethoxyethanol results in increased expression of ARF3 mRNA CTD PMID:19643169 NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002 		JBrowse link
G Atf2 activating transcription factor 2 increases expression EXP 2-ethoxyethanol results in increased expression of ATF2 mRNA CTD PMID:19643169 NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Bag6 BAG cochaperone 6 increases expression EXP 2-ethoxyethanol results in increased expression of BAG6 mRNA CTD PMID:19643169 NCBI chr20:3,680,607...3,693,329
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP 2-ethoxyethanol results in increased expression of BCL2L1 mRNA CTD PMID:19643169 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Cat catalase decreases activity EXP 2-ethoxyethanol results in decreased activity of CAT protein CTD PMID:20172899 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 increases expression EXP 2-ethoxyethanol results in increased expression of CAV mRNA CTD PMID:19643169 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression EXP 2-ethoxyethanol results in increased expression of CEBPG mRNA CTD PMID:19643169 NCBI chr 1:96,820,981...96,829,736
Ensembl chr 1:87,684,019...87,694,569 		JBrowse link
G Cel carboxyl ester lipase increases expression EXP 2-ethoxyethanol results in increased expression of CEL mRNA CTD PMID:19643169 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035 		JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 increases expression EXP 2-ethoxyethanol results in increased expression of CHP1 mRNA CTD PMID:19643169 NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:106,536,004...106,571,251 		JBrowse link
G Cltc clathrin heavy chain increases expression EXP 2-ethoxyethanol results in increased expression of CLTC mRNA CTD PMID:19643169 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 increases expression EXP 2-ethoxyethanol results in increased expression of CSNK1A1 mRNA CTD PMID:19643169 NCBI chr18:57,285,156...57,320,540
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Csnk1d casein kinase 1, delta increases expression EXP 2-ethoxyethanol results in increased expression of CSNK1D mRNA CTD PMID:19643169 NCBI chr10:106,713,497...106,754,953
Ensembl chr10:106,221,992...106,256,614 		JBrowse link
G Csnk1g3 casein kinase 1, gamma 3 increases expression EXP 2-ethoxyethanol results in increased expression of CSNK1G3 mRNA CTD PMID:19643169 NCBI chr18:49,497,839...49,584,828
Ensembl chr18:47,299,579...47,386,535 		JBrowse link
G Cttn cortactin increases expression EXP 2-ethoxyethanol results in increased expression of CTTN mRNA CTD PMID:19643169 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression EXP 2-ethoxyethanol results in increased expression of DHCR7 mRNA CTD PMID:19643169 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 decreases expression EXP 2-ethoxyethanol results in decreased expression of DYNC1LI1 mRNA CTD PMID:19643169 NCBI chr 8:123,254,823...123,288,496
Ensembl chr 8:114,376,662...114,410,934 		JBrowse link
G Eloa elongin A increases expression EXP 2-ethoxyethanol results in increased expression of ELOA mRNA CTD PMID:19643169 NCBI chr 5:148,231,600...148,246,760
Ensembl chr 5:148,231,596...148,246,765 		JBrowse link
G Eno2 enolase 2 increases expression EXP 2-ethoxyethanol results in increased expression of ENO2 mRNA CTD PMID:19643169 NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Epn2 epsin 2 increases expression EXP 2-ethoxyethanol results in increased expression of EPN2 mRNA CTD PMID:19643169 NCBI chr10:46,697,238...46,759,128
Ensembl chr10:46,197,785...46,259,642 		JBrowse link
G Gata4 GATA binding protein 4 increases expression EXP 2-ethoxyethanol results in increased expression of GATA4 mRNA CTD PMID:19643169 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gata6 GATA binding protein 6 increases expression EXP 2-ethoxyethanol results in increased expression of GATA6 mRNA CTD PMID:19643169 NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Gdi2 GDP dissociation inhibitor 2 increases expression EXP 2-ethoxyethanol results in increased expression of GDI2 mRNA CTD PMID:19643169 NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366 		JBrowse link
G Hk1 hexokinase 1 increases expression EXP 2-ethoxyethanol results in increased expression of HK1 mRNA CTD PMID:19643169 NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Hk2 hexokinase 2 increases expression EXP 2-ethoxyethanol results in increased expression of HK2 mRNA CTD PMID:19643169 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Igf2 insulin-like growth factor 2 increases expression EXP 2-ethoxyethanol results in increased expression of IGF2 mRNA CTD PMID:19643169 NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Jak2 Janus kinase 2 increases expression EXP 2-ethoxyethanol results in increased expression of JAK2 mRNA CTD PMID:19643169 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase increases expression EXP 2-ethoxyethanol results in increased expression of LYN mRNA CTD PMID:19643169 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 decreases expression EXP 2-ethoxyethanol results in decreased expression of MAP3K12 mRNA CTD PMID:19643169 NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:133,630,835...133,640,789 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases expression EXP 2-ethoxyethanol results in increased expression of MAPK1 mRNA CTD PMID:19643169 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk10 mitogen activated protein kinase 10 increases expression EXP 2-ethoxyethanol results in increased expression of MAPK10 mRNA CTD PMID:19643169 NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,497,707...6,786,201 		JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression EXP 2-ethoxyethanol results in increased expression of MXI1 mRNA CTD PMID:19643169 NCBI chr 1:262,329,274...262,389,037
Ensembl chr 1:252,323,303...252,383,681 		JBrowse link
G Nab1 Ngfi-A binding protein 1 increases expression EXP 2-ethoxyethanol results in increased expression of NAB1 mRNA CTD PMID:19643169 NCBI chr 9:49,053,579...49,093,078
Ensembl chr 9:49,053,758...49,092,098 		JBrowse link
G Nfia nuclear factor I/A increases expression EXP 2-ethoxyethanol results in increased expression of NFIA mRNA CTD PMID:19643169 NCBI chr 5:112,436,655...112,781,878
Ensembl chr 5:112,436,644...112,775,885 		JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 increases expression EXP 2-ethoxyethanol results in increased expression of NR2F2 mRNA CTD PMID:19643169 NCBI chr 1:133,419,161...133,434,290
Ensembl chr 1:124,009,181...124,022,031 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 increases expression EXP 2-ethoxyethanol results in increased expression of PAK2 mRNA CTD PMID:19643169 NCBI chr11:82,212,896...82,273,803
Ensembl chr11:68,707,969...68,768,816 		JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 increases expression EXP 2-ethoxyethanol results in increased expression of PFKFB2 mRNA CTD PMID:19643169 NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699 		JBrowse link
G Pla2g4a phospholipase A2 group 4A increases expression EXP 2-ethoxyethanol results in increased expression of PLA2G4A mRNA CTD PMID:19643169 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Plcb3 phospholipase C beta 3 increases expression EXP 2-ethoxyethanol results in increased expression of PLCB3 mRNA CTD PMID:19643169 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228 		JBrowse link
G Pou2f3 POU class 2 homeobox 3 increases expression EXP 2-ethoxyethanol results in increased expression of POU2F3 mRNA CTD PMID:19643169 NCBI chr 8:43,495,408...43,577,795
Ensembl chr 8:43,495,527...43,577,795 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha increases expression EXP 2-ethoxyethanol results in increased expression of PRKAR2A mRNA CTD PMID:19643169 NCBI chr 8:118,271,608...118,337,332
Ensembl chr 8:109,395,833...109,455,628 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family increases expression EXP 2-ethoxyethanol results in increased expression of RAB5A mRNA CTD PMID:19643169 NCBI chr 9:6,720,057...6,749,456
Ensembl chr 9:6,484,469...6,512,873 		JBrowse link
G Rnf4 ring finger protein 4 increases expression EXP 2-ethoxyethanol results in increased expression of RNF4 mRNA CTD PMID:19643169 NCBI chr14:80,625,864...80,647,138
Ensembl chr14:76,401,299...76,422,566 		JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase increases expression EXP 2-ethoxyethanol results in increased expression of ROS1 mRNA CTD PMID:19643169 NCBI chr20:31,432,636...31,583,998
Ensembl chr20:31,432,637...31,583,865 		JBrowse link
G Sec14l2 SEC14-like lipid binding 2 increases expression EXP 2-ethoxyethanol results in increased expression of SEC14L2 mRNA CTD PMID:19643169 NCBI chr14:78,973,805...78,998,480
Ensembl chr14:78,973,808...78,993,788 		JBrowse link
G Sik1 salt-inducible kinase 1 increases expression EXP 2-ethoxyethanol results in increased expression of SIK1 mRNA CTD PMID:19643169 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991 		JBrowse link
G Snrk SNF related kinase increases expression EXP 2-ethoxyethanol results in increased expression of SNRK mRNA CTD PMID:19643169 NCBI chr 8:130,657,204...130,711,461
Ensembl chr 8:121,793,302...121,832,323 		JBrowse link
G Snx16 sorting nexin 16 increases expression EXP 2-ethoxyethanol results in increased expression of SNX16 mRNA CTD PMID:19643169 NCBI chr 2:91,335,896...91,357,622
Ensembl chr 2:91,336,092...91,357,619 		JBrowse link
G Soat1 sterol O-acyltransferase 1 increases expression EXP 2-ethoxyethanol results in increased expression of SOAT1 mRNA CTD PMID:19643169 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494 		JBrowse link
G Stk17b serine/threonine kinase 17b increases expression EXP 2-ethoxyethanol results in increased expression of STK17B mRNA CTD PMID:19643169 NCBI chr 9:55,307,485...55,338,085
Ensembl chr 9:55,307,668...55,338,031 		JBrowse link
G Stx2 syntaxin 2 increases expression EXP 2-ethoxyethanol results in increased expression of STX2 mRNA CTD PMID:19643169 NCBI chr12:27,678,744...27,714,751
Ensembl chr12:27,689,819...27,714,751 		JBrowse link
G Stxbp1 syntaxin binding protein 1 increases expression EXP 2-ethoxyethanol results in increased expression of STXBP1 mRNA CTD PMID:19643169 NCBI chr 3:36,474,428...36,536,120
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
G Sycp1 synaptonemal complex protein 1 decreases expression EXP 2-ethoxyethanol results in decreased expression of SYCP1 mRNA CTD PMID:19643169 NCBI chr 2:190,296,688...190,456,687
Ensembl chr 2:190,296,954...190,456,737 		JBrowse link
G Sycp2 synaptonemal complex protein 2 decreases expression EXP 2-ethoxyethanol results in decreased expression of SYCP2 mRNA CTD PMID:19643169 NCBI chr 3:165,431,715...165,502,134
Ensembl chr 3:165,436,331...165,498,789 		JBrowse link
G Sycp3 synaptonemal complex protein 3 decreases expression EXP 2-ethoxyethanol results in decreased expression of SYCP3 mRNA CTD PMID:19643169 NCBI chr 7:22,874,055...22,888,512
Ensembl chr 7:22,874,055...22,888,511 		JBrowse link
G Tle4 TLE family member 4, transcriptional corepressor increases expression EXP 2-ethoxyethanol results in increased expression of TLE4 mRNA CTD PMID:19643169 NCBI chr 1:221,086,250...221,222,826
Ensembl chr 1:211,661,746...211,797,862 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 increases expression EXP 2-ethoxyethanol results in increased expression of TMED2 mRNA CTD PMID:19643169 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
G Wt1 WT1 transcription factor increases expression EXP 2-ethoxyethanol results in increased expression of WT1 mRNA CTD PMID:19643169 NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
G Yy1 YY1 transcription factor increases expression EXP 2-ethoxyethanol results in increased expression of YY1 mRNA CTD PMID:19643169 NCBI chr 6:133,471,615...133,500,875
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
G Zfp111 zinc finger protein 111 increases expression EXP 2-ethoxyethanol results in increased expression of ZFP111 mRNA CTD PMID:19643169 NCBI chr 1:79,762,897...79,774,274
Ensembl chr 1:79,762,782...79,775,608 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20856
    role 20816
      application 20617
        solvent 17470
          ethylene glycol 154
            2-ethoxyethanol 63
              2-ethoxyethyl 2-(4-\{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy\}phenoxy)propanoate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20856
    subatomic particle 20854
      composite particle 20854
        hadron 20854
          baryon 20854
            nucleon 20854
              atomic nucleus 20854
                atom 20854
                  main group element atom 20777
                    p-block element atom 20777
                      chalcogen 20489
                        oxygen atom 20455
                          oxygen molecular entity 20455
                            hydroxides 20228
                              organic hydroxy compound 19767
                                polyol 11904
                                  diol 3996
                                    glycol 3764
                                      glycol ether 947
                                        2-ethoxyethanol 63
                                          2-ethoxyethyl 2-(4-\{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy\}phenoxy)propanoate + 0
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