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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of nitric oxide biosynthetic process
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Accession:GO:0045429 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
Synonyms:exact_synonym: positive regulation of nitric oxide anabolism;   positive regulation of nitric oxide biosynthesis;   positive regulation of nitric oxide formation;   positive regulation of nitric oxide synthesis;   up regulation of nitric oxide biosynthetic process;   upregulation of nitric oxide biosynthetic process
 narrow_synonym: activation of nitric oxide biosynthetic process;   stimulation of nitric oxide biosynthetic process


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positive regulation of nitric oxide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen IDA RGD PMID:17616753 RGD:8548892 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 involved_in ISO (PMID:20018850) RGD PMID:20018850 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926 		JBrowse link
G Aif1 allograft inflammatory factor 1 IDA
IMP		 RGD PMID:16157606 PMID:16157606 RGD:2313017, RGD:2313017 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA		 (PMID:10376603)
GO_REF:0000107		 RGD
Ensembl		 PMID:10376603 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 IMP RGD PMID:18335029 RGD:2313325 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO		 GO_REF:0000107
(PMID:8995232)		 Ensembl
RGD		 PMID:8995232 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:O00206|UniProtKB:P16671|UniProtKB:Q9Y2C9 (PMID:20037584) RGD PMID:20037584 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Asl argininosuccinate lyase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:22081021)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:22081021 GO_REF:0000024 GO_REF:0000107 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662 		JBrowse link
G Ass1 argininosuccinate synthase 1 involved_in ISO (PMID:21106532) RGD PMID:21106532 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Cd36 CD36 molecule involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P05067-PRO_0000000092 (PMID:20037584)		 Ensembl
RGD		 PMID:20037584 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (PMID:19358895) RGD PMID:19358895 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Clu clusterin involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:15857407)
GO_REF:0000107		 Alzheimers_University_of_Toronto
RGD
Ensembl		 PMID:15857407 GO_REF:0000024 GO_REF:0000107 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 IMP RGD PMID:21620800 RGD:9685153 NCBI chr 1:135,300,048...135,407,688
Ensembl chr 1:135,300,461...135,409,760 		JBrowse link
G Crp C-reactive protein IDA RGD PMID:9767445 RGD:9586000 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 involved_in IMP
IBA
ISO		 GO_REF:0000033
(PMID:21493890)		 GO_Central
RGD		 PMID:21493890 PMID:12237779 GO_REF:0000033, RGD:727432 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339 		JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:16973909 RGD:9685181 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157 		JBrowse link
G Esr1 estrogen receptor 1 involved_in ISO
ISS		 (PMID:21937726)
GO_REF:0000024		 RGD
UniProt		 PMID:21937726 GO_REF:0000024 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Hrh1 histamine receptor H 1 IDA RGD PMID:12419527 RGD:727463 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12855682)		 UniProt
RGD		 PMID:12855682 GO_REF:0000024 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IMP RGD PMID:9062344 RGD:1600239 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifng interferon gamma involved_in
acts_upstream_of_or_within		 ISO (PMID:8383325)
(PMID:11168643)		 RGD PMID:8383325 PMID:11168643 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:8383325) RGD PMID:8383325 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 IDA RGD PMID:15845578 RGD:2306941 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Insr insulin receptor involved_in ISO (PMID:10747347) RGD PMID:10747347 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Itgb2 integrin subunit beta 2 IMP RGD PMID:9062344 RGD:1600239 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:12595539 RGD:1641934 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jak3 Janus kinase 3 IMP RGD PMID:22788969 RGD:11533941 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Klf2 KLF transcription factor 2 acts_upstream_of ISO (PMID:21768538) RGD PMID:21768538 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in ISO (PMID:22430140) RGD PMID:22430140 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12645935)		 Ensembl
RGD		 PMID:12645935 GO_REF:0000107 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Mir181a2 microRNA 181a-2 involved_in ISO RNAcentral:URS0000241987_9606|RNAcentral:URS00003DA300_9606 (PMID:22232059) RGD PMID:22232059 NCBI chr 3:22,615,845...22,615,961
Ensembl chr 3:22,615,845...22,615,961 		JBrowse link
G Mir181b1 microRNA 181b-1 involved_in ISO RNAcentral:URS0000229622_9606|RNAcentral:URS0000605E00_9606 (PMID:22232059) RGD PMID:22232059 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797 		JBrowse link
G Mir181b2 microRNA 181b-2 involved_in ISO RNAcentral:URS0000229622_9606 (PMID:22232059) RGD PMID:22232059 NCBI chr 3:22,616,948...22,617,035
Ensembl chr 3:22,616,948...22,617,035 		JBrowse link
G Mir29b1 microRNA 29b-1 IMP RGD PMID:29374012 RGD:13702880 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir99b microRNA 99b acts_upstream_of
involved_in		 ISO RNAcentral:URS00002C10B3_9606 (PMID:22232059)
RNAcentral:URS00001C308D_9606 (PMID:22232059)		 RGD PMID:22232059 NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:58,677,011...58,677,090 		JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:19576187 RGD:10041012 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24970700)		 UniProt
RGD		 PMID:24970700 GO_REF:0000024 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150 		JBrowse link
G Oprm1 opioid receptor, mu 1 involved_in ISO (PMID:20214800) RGD PMID:20214800 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta acts_upstream_of_or_within ISO (PMID:18558630) RGD PMID:18558630 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:19265036) RGD PMID:19265036 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in IMP PMID:9630216 BHF-UCL PMID:9630216 RGD:5135054 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:21926342 RGD:10041069 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Ptx3 pentraxin 3 acts_upstream_of_or_within ISO (PMID:14726497) RGD PMID:14726497 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 acts_upstream_of_or_within ISO MGI:3701255 (PMID:16476767) RGD PMID:16476767 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Smad3 SMAD family member 3 involved_in ISO
IGI		 (PMID:27038547) RGD PMID:27038547 PMID:27038547 RGD:11535100 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IMP RGD PMID:14720208 RGD:10042970 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO MGI:1857480 (PMID:15637112) RGD PMID:15637112 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IMP RGD PMID:22788969 RGD:11533941 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:2679794 (PMID:12872135) RGD PMID:12872135 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675 (PMID:10549626), (PMID:16239543) RGD PMID:10549626 PMID:16239543 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1860885 (PMID:10549626)
UniProtKB:P05067-PRO_0000000092 (PMID:20037584)		 Ensembl
RGD		 PMID:10549626 PMID:20037584 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr5 toll-like receptor 5 IDA RGD PMID:16973131 RGD:1643119 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO UniProtKB:O00206|UniProtKB:P05067-PRO_0000000092|UniProtKB:P16671 (PMID:20037584) RGD PMID:20037584 NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:8383325) RGD PMID:8383325 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 IMP RGD PMID:16081483 RGD:2317115 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) RGD PMID:12645935 NCBI chr 1:1,694,255...1,716,160 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20069
    cellular process 19150
      positive regulation of cellular process 6402
        positive regulation of metabolic process 3876
          positive regulation of nitric oxide metabolic process 58
            positive regulation of nitric oxide biosynthetic process 56
Path 2
Term Annotations click to browse term
  biological_process 20069
    biological regulation 13555
      regulation of biological process 13132
        regulation of cellular process 12767
          regulation of metabolic process 6743
            regulation of nitric oxide metabolic process 89
              regulation of nitric oxide biosynthetic process 86
                positive regulation of nitric oxide biosynthetic process 56
paths to the root