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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:capsaicin
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Accession:CHEBI:3374 term browser browse the term
Definition:A capsaicinoid that has formula C18H27NO3.
Synonyms:exact_synonym: (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide
 related_synonym: (E)-8-Methyl-N-vanillyl-6-nonenamide;   Formula=C18H27NO3;   InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+;   InChIKey=YKPUWZUDDOIDPM-SOFGYWHQSA-N;   Isodecenoic acid vanillylamide;   SMILES=COc1cc(CNC(=O)CCCC\\C=C\\C(C)C)ccc1O;   Zostrix;   trans-8-Methyl-N-vanillyl-6-nonenamide
 xref: BPDB:1630;   Beilstein:2816484;   CAS:404-86-4;   Drug_Central:3064;   KEGG:C06866;   KEGG:D00250
 xref_mesh: MESH:D002211
 xref: Wikipedia:Capsaicin


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capsaicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A member 1 multiple interactions
increases response to substance
increases expression		 EXP 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]; [Capsaicin results in increased expression of ABCA1 protein] which results in decreased uptake of Cholesterol; [Capsaicin results in increased expression of ABCA1 protein] which results in increased secretion of Cholesterol; APOE affects the reaction [Capsaicin results in increased expression of ABCA1 protein]; Cyclosporine affects the reaction [Capsaicin results in increased expression of ABCA1 protein]; KT 5720 inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]
ABCA1 results in increased susceptibility to Capsaicin		 CTD PMID:21908651 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895 		JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions
increases expression
decreases expression		 ISO Capsaicin affects the reaction [ABCB1 protein results in increased export of Digoxin]
Capsaicin results in increased expression of ABCB1 mRNA; Capsaicin results in increased expression of ABCB1 protein
Capsaicin results in decreased expression of ABCB1A mRNA		 CTD PMID:16674925 PMID:24013073 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B decreases expression ISO Capsaicin results in decreased expression of ABCB1B mRNA CTD PMID:24013073 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315 		JBrowse link
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase increases expression ISO Capsaicin results in increased expression of ABL1 mRNA CTD PMID:19502594 NCBI chr 2:31,578,256...31,697,105
Ensembl chr 2:31,578,388...31,694,239 		JBrowse link
G Acacb acetyl-Coenzyme A carboxylase beta decreases expression ISO Capsaicin results in decreased expression of ACACB mRNA CTD PMID:16278290 NCBI chr 5:114,284,748...114,388,822
Ensembl chr 5:114,284,596...114,388,822 		JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl increases expression ISO Capsaicin results in increased expression of ACOX1 mRNA CTD PMID:18533110 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO Capsaicin results in decreased expression of ACSL3 mRNA CTD PMID:18533110 NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases secretion
increases expression		 EXP Capsaicin results in increased secretion of ADIPOQ protein
Capsaicin results in increased expression of ADIPOQ mRNA; Capsaicin results in increased expression of ADIPOQ protein		 CTD PMID:17295509 PMID:17719033 PMID:19798065 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778 		JBrowse link
G Adra2a adrenergic receptor, alpha 2a decreases response to substance EXP ADRA2A results in decreased susceptibility to Capsaicin CTD PMID:15220790 NCBI chr19:54,033,690...54,037,413
Ensembl chr19:54,032,582...54,037,413 		JBrowse link
G Aga aspartylglucosaminidase decreases expression ISO Capsaicin results in decreased expression of AGA mRNA CTD PMID:16278290 NCBI chr 8:53,964,718...53,976,457
Ensembl chr 8:53,964,762...53,976,456 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO Capsaicin results in increased expression of AGTR1A mRNA CTD PMID:20349343 NCBI chr13:30,520,339...30,566,850
Ensembl chr13:30,520,424...30,566,850 		JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions EXP Capsaicin inhibits the reaction [Methylcholanthrene results in increased activity of and results in increased localization of AHR protein] CTD PMID:21250977 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 affects localization ISO Capsaicin affects the localization of AIFM1 protein CTD PMID:20925121 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440 		JBrowse link
G Akirin2 akirin 2 increases expression ISO Capsaicin results in increased expression of AKIRIN2 mRNA CTD PMID:16278290 NCBI chr 4:34,550,615...34,566,930
Ensembl chr 4:34,550,937...34,566,908 		JBrowse link
G Akr1a1 aldo-keto reductase family 1, member A1 multiple interactions ISO Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of AKR1A1 protein] CTD PMID:20359164 NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases expression
increases phosphorylation
multiple interactions
increases activity		 ISO
EXP		 Capsaicin results in increased expression of AKT1 protein modified form
Capsaicin results in increased phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of AKT1 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of AKT1 protein]; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of AKT1 protein]; wortmannin inhibits the reaction [Capsaicin results in increased phosphorylation of AKT1 protein]
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Capsaicin co-treated with Oxygen deficiency co-treated with Oxygen] results in increased phosphorylation of AKT1 protein]; [Capsaicin co-treated with Oxygen deficiency co-treated with Oxygen] results in increased phosphorylation of AKT1 protein
Capsaicin results in increased activity of AKT1 protein		 CTD PMID:16360265 PMID:17084039 PMID:17979524 PMID:19011674 PMID:19059400 More... NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Alb albumin increases expression ISO Capsaicin results in increased expression of ALB protein CTD PMID:9537786 PMID:18991268 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase family 3, subfamily A1 decreases expression ISO Capsaicin results in decreased expression of ALDH3A1 mRNA CTD PMID:16278290 NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
decreases activity		 ISO [Capsaicin co-treated with Curcumin] results in decreased activity of ALOX5 protein
Capsaicin results in decreased activity of ALOX5 protein		 CTD PMID:16956363 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139 		JBrowse link
G Amhr2 anti-Mullerian hormone type 2 receptor decreases expression ISO Capsaicin results in decreased expression of AMHR2 mRNA CTD PMID:16278290 NCBI chr15:102,353,437...102,363,075
Ensembl chr15:102,353,802...102,363,068 		JBrowse link
G Amn amnionless multiple interactions
increases expression		 ISO AMN protein inhibits the reaction [Capsaicin results in increased expression of SST protein]; AMN protein inhibits the reaction [Capsaicin results in increased expression of TAC1 protein]
Capsaicin results in increased expression of AMN protein		 CTD PMID:16938409 NCBI chr12:111,237,530...111,242,860
Ensembl chr12:111,237,529...111,242,860 		JBrowse link
G Angpt1 angiopoietin 1 increases expression ISO Capsaicin results in increased expression of ANGPT1 mRNA CTD PMID:21310942 NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373 		JBrowse link
G Angpt2 angiopoietin 2 increases expression ISO Capsaicin results in increased expression of ANGPT2 mRNA CTD PMID:21310942 NCBI chr 8:18,740,279...18,791,578
Ensembl chr 8:18,740,279...18,791,578 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Capsaicin results in increased expression of APAF1 mRNA CTD PMID:19502594 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632 		JBrowse link
G Apob apolipoprotein B increases expression ISO Capsaicin results in increased expression of APOB mRNA CTD PMID:16278290 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835 		JBrowse link
G Apoc1 apolipoprotein C-I decreases expression ISO Capsaicin results in decreased expression of APOC1 mRNA CTD PMID:18533110 NCBI chr 7:19,423,405...19,426,584
Ensembl chr 7:19,423,406...19,426,585 		JBrowse link
G Apoe apolipoprotein E multiple interactions EXP APOE affects the reaction [Capsaicin results in decreased expression of LRP1 protein]; APOE affects the reaction [Capsaicin results in increased expression of ABCA1 protein]; Capsaicin inhibits the reaction [[APOE affects the susceptibility to Dietary Fats] which affects the abundance of Cholesterol]; Capsaicin inhibits the reaction [[APOE affects the susceptibility to Dietary Fats] which affects the abundance of Triglycerides] CTD PMID:21908651 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Aqp1 aquaporin 1 increases response to substance EXP AQP1 results in increased susceptibility to Capsaicin CTD PMID:20018876 NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540 		JBrowse link
G Ar androgen receptor increases expression
multiple interactions		 ISO Capsaicin results in increased expression of AR protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of AR protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of AR protein]; Capsaicin inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Capsaicin inhibits the reaction [Dihydrotestosterone results in increased expression of AR protein]; capsazepine inhibits the reaction [Capsaicin results in increased expression of AR protein]; iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of AR protein]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin results in increased expression of AR protein]		 CTD PMID:16540674 PMID:19059400 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Areg amphiregulin multiple interactions EXP [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA] CTD PMID:20660715 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291 		JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 increases expression ISO Capsaicin results in increased expression of ARPP19 mRNA CTD PMID:16278290 NCBI chr 9:74,944,896...74,967,595
Ensembl chr 9:74,944,896...74,967,595 		JBrowse link
G Arrdc4 arrestin domain containing 4 decreases expression ISO Capsaicin results in decreased expression of ARRDC4 mRNA CTD PMID:33512557 NCBI chr 7:68,386,742...68,398,986
Ensembl chr 7:68,386,743...68,398,989 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO ATF3 mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]; Capsaicin promotes the reaction [CEBPB protein binds to ATF3 protein binds to GSK3B protein] CTD PMID:20110283 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
affects localization		 ISO Cycloheximide inhibits the reaction [Capsaicin results in increased expression of ATF4 protein]
Capsaicin affects the localization of ATF4 protein		 CTD PMID:18533110 PMID:19139269 PMID:20925121 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742 		JBrowse link
G Atg16l1 autophagy related 16 like 1 decreases expression ISO Capsaicin results in decreased expression of ATG16L1 mRNA CTD PMID:20349343 NCBI chr 1:87,683,730...87,720,150
Ensembl chr 1:87,683,592...87,720,150 		JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases expression		 ISO ATG5 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein]; ATG5 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of PRKDC protein]
Capsaicin results in increased expression of ATG5 protein		 CTD PMID:22226932 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287 		JBrowse link
G Atm ataxia telangiectasia mutated increases activity
increases expression
increases phosphorylation
multiple interactions		 ISO Capsaicin results in increased activity of ATM protein
Capsaicin results in increased expression of ATM mRNA
Capsaicin results in increased phosphorylation of ATM protein
3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein]; ATG5 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein]; Capsaicin results in increased phosphorylation of and results in increased activity of ATM protein		 CTD PMID:19502594 PMID:22226932 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040 		JBrowse link
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 affects metabolic processing
decreases expression		 ISO Capsaicin affects the metabolism of ATP2A2 protein
Capsaicin results in decreased expression of ATP2A2 protein modified form		 CTD PMID:18037908 NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288 		JBrowse link
G Atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 decreases expression ISO Capsaicin results in decreased expression of ATP6AP1 mRNA CTD PMID:16278290 NCBI chr  X:73,340,753...73,348,297
Ensembl chr  X:73,340,703...73,348,327 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Capsaicin results in increased expression of BAD mRNA CTD PMID:19502594 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bag3 BCL2-associated athanogene 3 increases expression ISO Capsaicin results in increased expression of BAG3 mRNA CTD PMID:19502594 NCBI chr 7:128,125,307...128,148,705
Ensembl chr 7:128,125,340...128,148,705 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases activity
increases expression		 EXP
ISO		 Capsaicin results in increased activity of BAK1 protein
Capsaicin results in increased expression of BAK1 mRNA		 CTD PMID:17295509 PMID:19502594 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983 		JBrowse link
G Bax BCL2-associated X protein multiple interactions
increases activity
increases expression
affects localization
affects expression		 ISO
EXP		 TP53 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]; TRPV6 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]
Capsaicin results in increased activity of BAX protein
Capsaicin affects the localization of BAX protein
Capsaicin results in increased expression of BAX; Capsaicin results in increased expression of BAX mRNA; Capsaicin results in increased expression of BAX protein
Capsaicin affects the expression of BAX protein		 CTD PMID:16540674 PMID:17292493 PMID:17295509 PMID:19002586 PMID:19331147 More... NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcan brevican decreases expression ISO Capsaicin results in decreased expression of BCAN mRNA CTD PMID:16278290 NCBI chr 3:87,894,839...87,908,458
Ensembl chr 3:87,894,838...87,907,537 		JBrowse link
G Bcl10 B cell leukemia/lymphoma 10 increases expression ISO Capsaicin results in increased expression of BCL10 mRNA CTD PMID:19502594 NCBI chr 3:145,630,017...145,640,121
Ensembl chr 3:145,628,559...145,640,111 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases response to substance
decreases expression
increases expression
affects expression		 ISO
EXP		 BCL2 protein results in decreased susceptibility to Capsaicin
Capsaicin results in decreased expression of BCL2; Capsaicin results in decreased expression of BCL2 protein
Capsaicin results in increased expression of BCL2 mRNA
Capsaicin affects the expression of BCL2 protein		 CTD PMID:9580328 PMID:11275362 PMID:15595419 PMID:17295509 PMID:17306913 More... NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression
increases expression		 ISO Capsaicin results in decreased expression of BCL2L1 protein
Capsaicin results in increased expression of BCL2L1 mRNA		 CTD PMID:17505005 PMID:19502594 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 increases expression ISO Capsaicin results in increased expression of BCLAF1 mRNA CTD PMID:19502594 NCBI chr10:20,187,897...20,218,390
Ensembl chr10:20,188,215...20,220,359 		JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [Capsaicin results in increased expression of BDKRB1 mRNA]; capsazepine inhibits the reaction [Capsaicin results in increased expression of BDKRB1 mRNA]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin results in increased expression of BDKRB1 mRNA] CTD PMID:22264228 NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687 		JBrowse link
G Bdkrb2 bradykinin receptor, beta 2 multiple interactions ISO Capsaicin inhibits the reaction [[KNG1 protein alternative form binds to and results in increased activity of BDKRB2 protein] which results in increased abundance of Inositol Phosphates]
BDKRB2 affects the reaction [Capsaicin results in increased activity of TRPV1 protein]; BDKRB2 affects the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]		 CTD PMID:15363968 PMID:17347322 NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496 		JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions
affects expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of BDNF protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of BDNF protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of BDNF protein] CTD PMID:22150557 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352 		JBrowse link
G Becn1 beclin 1, autophagy related increases expression ISO Capsaicin results in increased expression of BECN1 mRNA CTD PMID:20349343 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
increases expression
multiple interactions		 ISO Capsaicin results in increased cleavage of BID protein
Capsaicin results in increased expression of BID mRNA
Capsaicin promotes the reaction [TNFSF10 results in increased cleavage of BID protein]		 CTD PMID:19502594 PMID:22200406 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO Capsaicin results in increased expression of BIRC2 mRNA CTD PMID:19502594 NCBI chr 9:7,818,227...7,837,123
Ensembl chr 9:7,818,228...7,837,065 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression
multiple interactions		 ISO Capsaicin results in decreased expression of BIRC5; Capsaicin results in decreased expression of BIRC5 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in decreased expression of BIRC5 protein]; BIRC5 results in decreased activity of [Capsaicin co-treated with TNFSF10 protein]		 CTD PMID:17505005 PMID:19002586 PMID:19939880 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Bnip2 BCL2/adenovirus E1B interacting protein 2 increases expression ISO Capsaicin results in increased expression of BNIP2 mRNA CTD PMID:19502594 NCBI chr 9:69,896,660...69,918,941
Ensembl chr 9:69,896,748...69,915,599 		JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 decreases expression
increases expression		 ISO Capsaicin results in decreased expression of BNIP3 mRNA
Capsaicin results in increased expression of BNIP3 mRNA		 CTD PMID:19502594 PMID:36044967 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like decreases expression
increases expression		 ISO Capsaicin results in decreased expression of BNIP3L mRNA
Capsaicin results in increased expression of BNIP3L mRNA		 CTD PMID:19502594 PMID:36044967 NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326 		JBrowse link
G Cacng3 calcium channel, voltage-dependent, gamma subunit 3 decreases expression ISO Capsaicin results in decreased expression of CACNG3 mRNA CTD PMID:16278290 NCBI chr 7:122,270,967...122,368,616
Ensembl chr 7:122,269,715...122,368,616 		JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha increases expression
increases secretion
multiple interactions
affects response to substance
decreases expression		 ISO
EXP		 Capsaicin results in increased expression of CALCA mRNA; Capsaicin results in increased expression of CALCA protein
Capsaicin results in increased secretion of CALCA protein
[Capsaicin co-treated with Ethanol] results in increased expression of CALCA protein; CALCA protein affects the reaction [Capsaicin results in decreased susceptibility to Ethanol]; CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 mRNA]; CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 protein]; CALCA protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]; CNR1 protein affects the reaction [Capsaicin results in increased secretion of CALCA protein]; rimabotulinumtoxinB inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]
CALCA protein affects the susceptibility to Capsaicin
CALCA protein alternative form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; capsazepine inhibits the reaction [Capsaicin results in increased expression of CALCA mRNA]
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; [Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein; [Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein; [Capsaicin results in decreased susceptibility to safranal] which results in decreased secretion of CALCA protein; botulinum toxin type D inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; butaprost promotes the reaction [Capsaicin results in increased secretion of CALCA protein]; Calcium affects the reaction [Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium affects the reaction [Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]]; Calcium affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Capsaicin inhibits the reaction [Freund's Adjuvant results in increased expression of CALCA mRNA]; Capsaicin inhibits the reaction [monophosphoryl lipid A results in increased expression of CALCA mRNA]; Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]; Capsaicin inhibits the reaction [Nitroglycerin results in increased expression of CALCA mRNA]; Capsaicin promotes the reaction [Phenol results in decreased expression of CALCA protein]; Capsaicin results in increased secretion of [CALCA protein co-treated with CALCB protein]; capsazepine inhibits the reaction [Capsaicin results in increased expression of CALCA protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of [CALCA protein co-treated with CALCB protein]]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Carbon Dioxide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; chelerythrine inhibits the reaction [Capsaicin results in increased expression of CALCA protein]; Dinoprostone promotes the reaction [Capsaicin results in increased secretion of CALCA protein]; Enkephalin, Ala(2)-MePhe(4)-Gly(5)- inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; epothilone B affects the reaction [[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein]; iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of CALCA protein]; mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Nefopam inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; neuropeptide Y, Leu(31)-Pro(34)- inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; NGF protein promotes the reaction [Capsaicin results in increased expression of CALCA protein]; nociceptin (1-13) amide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; OPRL1 protein promotes the reaction [nociceptin (1-13) amide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Paclitaxel inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Plant Extracts inhibits the reaction [Capsaicin results in decreased expression of CALCA protein]; Plant Extracts inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Polyphenols inhibits the reaction [Capsaicin results in decreased expression of CALCA protein]; Polyphenols inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; PPP3CA protein affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; TRPV1 protein affects the reaction [Capsaicin results in increased secretion of CALCA protein]
Capsaicin results in decreased expression of CALCA mRNA; Capsaicin results in decreased expression of CALCA protein		 CTD PMID:2462184 PMID:3412491 PMID:7473211 PMID:8971780 PMID:11738242 More... NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592 		JBrowse link
G Calcb calcitonin-related polypeptide, beta increases expression
increases secretion
multiple interactions
decreases activity		 ISO Capsaicin results in increased expression of CALCB mRNA
Capsaicin results in increased secretion of CALCB protein
capsazepine inhibits the reaction [Capsaicin results in increased expression of CALCB mRNA]
Capsaicin results in increased secretion of [CALCA protein co-treated with CALCB protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of [CALCA protein co-treated with CALCB protein]]
CALCB protein alternative form results in decreased activity of Capsaicin		 CTD PMID:9932722 PMID:14764656 PMID:17434803 PMID:18584893 NCBI chr 7:114,315,790...114,322,603
Ensembl chr 7:114,317,878...114,322,600 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions ISO Capsaicin results in increased phosphorylation of and results in increased expression of CAMK2A protein CTD PMID:12019337 NCBI chr18:61,058,704...61,121,224
Ensembl chr18:61,058,690...61,121,224 		JBrowse link
G Camp cathelicidin antimicrobial peptide multiple interactions
increases expression		 ISO Glyoxal promotes the reaction [Capsaicin results in increased expression of CAMP protein] CTD PMID:29496360 NCBI chr 9:109,676,445...109,678,524
Ensembl chr 9:109,676,447...109,678,685 		JBrowse link
G Casp2 caspase 2 multiple interactions ISO [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP2 protein CTD PMID:19939880 NCBI chr 6:42,241,942...42,259,442
Ensembl chr 6:42,241,919...42,259,442 		JBrowse link
G Casp3 caspase 3 increases expression
increases activity
increases cleavage
affects expression
multiple interactions
affects activity
affects cleavage		 ISO
EXP		 Capsaicin results in increased expression of CASP3 protein
Capsaicin results in increased activity of CASP3 protein
Capsaicin results in increased cleavage of CASP3 protein
Capsaicin affects the expression of CASP3 protein
[ND1 gene mutant form results in increased susceptibility to Capsaicin] which results in increased activity of CASP3 protein; Capsaicin promotes the reaction [resveratrol results in increased activity of CASP3 protein]; Capsaicin promotes the reaction [TNFSF10 protein results in increased cleavage of CASP3 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP3 protein]; Capsaicin promotes the reaction [TRPV1 protein results in increased activity of CASP3 protein]; Capsaicin results in increased cleavage of and results in increased activity of CASP3 protein; capsazepine inhibits the reaction [Capsaicin results in increased cleavage of and results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [Capsaicin results in increased cleavage of CASP3 protein]; EUK-134 inhibits the reaction [Capsaicin results in increased cleavage of CASP3 protein]; resveratrol promotes the reaction [Capsaicin results in increased activity of CASP3 protein]
Capsaicin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in increased activity of CASP3 protein]
Capsaicin affects the activity of CASP3 protein
Capsaicin affects the cleavage of CASP3 protein		 CTD PMID:11275362 PMID:16125681 PMID:16477149 PMID:17295509 PMID:17306913 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase increases activity
increases expression
multiple interactions		 ISO Capsaicin results in increased activity of CASP4 protein
Capsaicin results in increased expression of CASP4 mRNA
Capsaicin results in increased cleavage of and results in increased activity of CASP4 protein		 CTD PMID:19139269 PMID:19699254 PMID:20349343 PMID:20371669 NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783 		JBrowse link
G Casp6 caspase 6 multiple interactions ISO [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP6 protein CTD PMID:19939880 NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752 		JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity		 ISO [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP7 protein
Capsaicin results in increased activity of CASP7 protein		 CTD PMID:19139269 PMID:19699254 PMID:19855437 PMID:19939880 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776 		JBrowse link
G Casp8 caspase 8 increases activity
increases expression
multiple interactions
decreases expression		 ISO Capsaicin results in increased activity of CASP8 protein
Capsaicin results in increased expression of CASP8 mRNA
[Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP8 protein; Capsaicin promotes the reaction [resveratrol results in decreased expression of CASP8 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP8 protein]; resveratrol promotes the reaction [Capsaicin results in decreased expression of CASP8 protein]		 CTD PMID:19502594 PMID:19846903 PMID:19939880 PMID:22200406 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 increases cleavage
increases expression
affects expression
multiple interactions
increases activity		 ISO Capsaicin results in increased cleavage of CASP9 protein
Capsaicin results in increased expression of CASP9 mRNA
Capsaicin affects the expression of CASP9 protein
Capsaicin results in increased expression of CASP9 protein
[Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP9 protein; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP9 protein]; CAT protein inhibits the reaction [Capsaicin results in increased cleavage of CASP9 protein]; EUK-134 inhibits the reaction [Capsaicin results in increased cleavage of CASP9 protein]
Capsaicin results in increased activity of CASP9 protein		 CTD PMID:16125681 PMID:16477149 PMID:19502594 PMID:19699254 PMID:19855437 More... NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cat catalase multiple interactions ISO
EXP		 CAT protein inhibits the reaction [Capsaicin results in increased cleavage of CASP3 protein]; CAT protein inhibits the reaction [Capsaicin results in increased cleavage of CASP9 protein]; CAT protein inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]
Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased expression of CAT]		 CTD PMID:14871840 PMID:18023135 PMID:18338764 PMID:21647434 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Cck cholecystokinin multiple interactions EXP
ISO		 [Capsaicin co-treated with CCK protein alternative form] results in increased expression of TAC1 protein; Capsaicin inhibits the reaction [CCK protein alternative form results in decreased expression of NGF mRNA]; Capsaicin promotes the reaction [CCK protein alternative form results in increased expression of NGF protein]
Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK3 protein]		 CTD PMID:10683199 PMID:22508518 NCBI chr 9:121,318,890...121,324,728
Ensembl chr 9:121,318,890...121,324,760 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression ISO Capsaicin results in increased expression of CCL19 mRNA CTD PMID:20349343 NCBI chr 4:42,754,525...42,756,558
Ensembl chr 4:42,754,525...42,756,577 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
decreases secretion
multiple interactions
increases expression		 EXP
ISO		 Capsaicin results in decreased expression of CCL2 mRNA; Capsaicin results in decreased expression of CCL2 protein
Capsaicin results in decreased secretion of CCL2 protein
capsazepine inhibits the reaction [Capsaicin results in decreased secretion of CCL2 protein]; troglitazone promotes the reaction [Capsaicin results in decreased secretion of CCL2 protein]
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL2 protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of CCL2 protein]
Capsaicin results in increased expression of CCL2 mRNA; Capsaicin results in increased expression of CCL2 protein
Capsaicin promotes the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]		 CTD PMID:17719033 PMID:19798065 PMID:20349343 PMID:22150557 PMID:30244119 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of CCL20 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL20 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL20 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCL20 protein]		 CTD PMID:22150557 NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL22 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL22 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCL22 protein] CTD PMID:22150557 NCBI chr 8:95,472,312...95,478,016
Ensembl chr 8:95,472,218...95,478,327 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression		 ISO Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CCL3 mRNA]]
Capsaicin results in increased expression of CCL3 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCL3 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCL3 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCL3 protein]		 CTD PMID:21745629 PMID:22150557 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Capsaicin results in decreased expression of CCNA2 protein CTD PMID:19939880 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Capsaicin results in decreased expression of CCNB1 protein CTD PMID:19939880 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Capsaicin results in decreased expression of CCND1 protein CTD PMID:17505005 PMID:19855437 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Ccnl1 cyclin L1 increases expression ISO Capsaicin results in increased expression of CCNL1 mRNA CTD PMID:20349343 NCBI chr 3:65,853,333...65,869,451
Ensembl chr 3:65,853,572...65,865,670 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of CCR4 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CCR4 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CCR4 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CCR4 protein]		 CTD PMID:22150557 NCBI chr 9:114,319,384...114,334,544
Ensembl chr 9:114,319,384...114,333,984 		JBrowse link
G Cd46 CD46 antigen, complement regulatory protein increases expression ISO Capsaicin results in increased expression of CD46 mRNA CTD PMID:16278290 NCBI chr 1:194,721,279...194,781,149
Ensembl chr 1:194,719,134...194,774,557 		JBrowse link
G Cd68 CD68 antigen decreases expression EXP Capsaicin results in decreased expression of CD68 mRNA CTD PMID:19798065 NCBI chr11:69,555,039...69,556,996
Ensembl chr11:69,555,039...69,556,979 		JBrowse link
G Cd80 CD80 antigen increases expression
multiple interactions		 ISO Capsaicin results in increased expression of CD80 protein
[Naproxen co-treated with Sumatriptan] affects the reaction [Capsaicin results in increased expression of CD80 protein]; Naproxen affects the reaction [Capsaicin results in increased expression of CD80 protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of CD80 protein]		 CTD PMID:22150557 NCBI chr16:38,277,793...38,316,682
Ensembl chr16:38,275,923...38,316,697 		JBrowse link
G Cd8b1 CD8 subunit beta 1 increases expression ISO Capsaicin results in increased expression of CD8B mRNA CTD PMID:16278290 NCBI chr 6:71,299,772...71,314,476
Ensembl chr 6:71,299,772...71,314,478 		JBrowse link
G Cdc14a CDC14 cell division cycle 14A increases expression ISO Capsaicin results in increased expression of CDC14A mRNA CTD PMID:20349343 NCBI chr 3:116,066,202...116,222,390
Ensembl chr 3:116,066,202...116,222,394 		JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of CDH1 protein
acadesine promotes the reaction [Capsaicin results in increased expression of CDH1 protein]; bafilomycin A1 inhibits the reaction [Capsaicin results in increased expression of CDH1 protein]; dorsomorphin inhibits the reaction [Capsaicin results in increased expression of CDH1 protein]		 CTD PMID:36044967 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878 		JBrowse link
G Cdh2 cadherin 2 multiple interactions
decreases expression		 ISO acadesine promotes the reaction [Capsaicin results in decreased expression of CDH2 protein]; bafilomycin A1 inhibits the reaction [Capsaicin results in decreased expression of CDH2 protein]; dorsomorphin inhibits the reaction [Capsaicin results in decreased expression of CDH2 protein] CTD PMID:36044967 NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303 		JBrowse link
G Cdk1 cyclin dependent kinase 1 increases expression ISO Capsaicin results in increased expression of CDK1 mRNA CTD PMID:20349343 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Capsaicin results in decreased expression of CDK2 protein CTD PMID:20646592 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900 		JBrowse link
G Cdk4 cyclin dependent kinase 4 decreases expression ISO Capsaicin results in decreased expression of CDK4 mRNA CTD PMID:16278290 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression
decreases expression		 ISO Capsaicin results in increased expression of CDKN1A mRNA; Capsaicin results in increased expression of CDKN1A protein
Capsaicin results in decreased expression of CDKN1A protein		 CTD PMID:16540674 PMID:19502594 PMID:20646592 PMID:22226932 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B increases expression
decreases expression		 EXP
ISO		 Capsaicin results in increased expression of CDKN1B
Capsaicin results in decreased expression of CDKN1B protein
Capsaicin results in increased expression of CDKN1B protein		 CTD PMID:19855437 PMID:20069556 PMID:22226932 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A increases expression ISO Capsaicin results in increased expression of CDKN2A mRNA CTD PMID:18533110 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
multiple interactions		 EXP
ISO		 Capsaicin results in decreased expression of CEBPA protein
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of CEBPA mRNA]		 CTD PMID:17295509 PMID:20359164 NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
increases activity		 ISO
EXP		 [CEBPB protein binds to GDF15 promoter] promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA]; Capsaicin promotes the reaction [CEBPB protein binds to ATF3 protein binds to GSK3B protein]; CEBPB mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]; CEBPB protein promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA]
[Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]		 CTD PMID:20110283 PMID:21250977 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Cfl1 cofilin 1, non-muscle multiple interactions ISO [Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] which results in increased import of Calcium; Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein; Egtazic Acid inhibits the reaction [Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] CTD PMID:17303079 NCBI chr19:5,540,483...5,544,059
Ensembl chr19:5,540,483...5,545,229 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression
decreases expression		 ISO Capsaicin results in increased expression of CFLAR mRNA
Capsaicin results in decreased expression of CFLAR protein alternative form		 CTD PMID:19502594 PMID:19939880 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator increases activity EXP Capsaicin results in increased activity of CFTR protein; Capsaicin results in increased activity of CFTR protein mutant form CTD PMID:15155835 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO Capsaicin results in increased expression of CHEK2 mRNA CTD PMID:19502594 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011 		JBrowse link
G Ciita class II transactivator multiple interactions EXP Capsaicin inhibits the reaction [IFNG protein results in increased expression of CIITA mRNA] CTD PMID:19825429 NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282 		JBrowse link
G Cilk1 ciliogenesis associated kinase 1 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of CILK1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CILK1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CILK1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CILK1 protein]		 CTD PMID:22150557 NCBI chr 9:78,016,425...78,079,396
Ensembl chr 9:78,016,474...78,079,389 		JBrowse link
G Cldn1 claudin 1 increases expression ISO Capsaicin results in increased expression of CLDN1 mRNA CTD PMID:16278290 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591 		JBrowse link
G Clec2d C-type lectin domain family 2, member d decreases expression ISO Capsaicin results in decreased expression of CLEC2D mRNA CTD PMID:16278290 NCBI chr 6:129,157,578...129,163,498
Ensembl chr 6:129,157,578...129,163,497 		JBrowse link
G Clk1 CDC-like kinase 1 increases expression ISO Capsaicin results in increased expression of CLK1 mRNA CTD PMID:20349343 NCBI chr 1:58,451,147...58,463,247
Ensembl chr 1:58,449,348...58,463,225 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
affects response to substance
increases activity		 EXP
ISO		 CNR1 protein affects the reaction [Capsaicin results in increased secretion of CALCA protein]
CNR1 protein affects the susceptibility to Capsaicin
Capsaicin results in increased activity of CNR1 protein		 CTD PMID:11408034 PMID:18987195 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831 		JBrowse link
G Cntf ciliary neurotrophic factor increases expression
multiple interactions		 ISO Capsaicin results in increased expression of CNTF protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CNTF protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CNTF protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CNTF protein]		 CTD PMID:22150557 NCBI chr19:12,740,892...12,742,996
Ensembl chr19:12,741,024...12,742,996 		JBrowse link
G Cntfr ciliary neurotrophic factor receptor multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CNTFR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CNTFR protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CNTFR protein] CTD PMID:22150557 NCBI chr 4:41,657,498...41,697,091
Ensembl chr 4:41,657,498...41,697,089 		JBrowse link
G Col18a1 collagen, type XVIII, alpha 1 increases expression ISO Capsaicin results in increased expression of COL18A1 mRNA CTD PMID:21310942 NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382 		JBrowse link
G Col1a1 collagen, type I, alpha 1 increases expression ISO Capsaicin results in increased expression of COL1A1 mRNA CTD PMID:20349343 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868 		JBrowse link
G Col3a1 collagen, type III, alpha 1 increases expression ISO Capsaicin results in increased expression of COL3A1 mRNA CTD PMID:20349343 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866 		JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4I1 increases expression ISO Capsaicin results in increased expression of COX4I1 protein CTD PMID:18079164 NCBI chr 8:121,394,964...121,400,948
Ensembl chr 8:121,394,961...121,400,946 		JBrowse link
G Cox5a cytochrome c oxidase subunit 5A increases expression ISO Capsaicin results in increased expression of COX5A protein CTD PMID:18991268 NCBI chr 9:57,423,012...57,439,710
Ensembl chr 9:57,428,557...57,439,709 		JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 increases expression ISO Capsaicin results in increased expression of COX6A1 mRNA CTD PMID:16278290 NCBI chr 5:115,483,711...115,487,017
Ensembl chr 5:115,483,701...115,487,040 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions
increases expression		 ISO Capsaicin promotes the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]
Capsaicin results in increased expression of CPT1A mRNA
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of CPT1A mRNA]		 CTD PMID:20359164 PMID:21745629 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; NPC 15437 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; Ro 31-8425 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; U 0126 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein] CTD PMID:15385614 PMID:15631885 PMID:16159392 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707 		JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) increases expression
multiple interactions		 ISO Capsaicin results in increased expression of CSF2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CSF2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CSF2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CSF2 protein]		 CTD PMID:22150557 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493 		JBrowse link
G Csnk2a1 casein kinase 2, alpha 1 polypeptide increases phosphorylation ISO Capsaicin results in increased phosphorylation of CSNK2A1 protein CTD PMID:20510015 NCBI chr 2:152,068,468...152,123,772
Ensembl chr 2:152,068,759...152,123,772 		JBrowse link
G Csnk2b casein kinase 2, beta polypeptide increases phosphorylation ISO Capsaicin results in increased phosphorylation of CSNK2B protein CTD PMID:20510015 NCBI chr17:35,335,171...35,341,029
Ensembl chr17:35,335,172...35,341,029 		JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of CTNNB1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CTNNB1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CTNNB1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CTNNB1 protein]		 CTD PMID:22150557 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 affects expression
multiple interactions		 ISO Capsaicin affects the expression of CX3CL1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of CX3CL1 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of CX3CL1 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of CX3CL1 protein]		 CTD PMID:22150557 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of CXCL10 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCL10 protein]		 CTD PMID:22150557 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748 		JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
affects expression
decreases expression
increases expression
increases secretion		 ISO 7-oxozeanol inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]; AM 251 promotes the reaction [Capsaicin results in increased secretion of CXCL8 protein]; Capsaicin inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Capsaicin inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein]; Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CXCL8 mRNA]; Capsaicin inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; capsazepine inhibits the reaction [Capsaicin results in increased expression of CXCL8 mRNA]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased secretion of CXCL8 protein]; Egtazic Acid inhibits the reaction [Capsaicin results in increased expression of CXCL8 mRNA]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin inhibits the reaction [Palmitic Acid results in increased expression of CXCL8 mRNA]]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]; RTKI cpd affects the reaction [Capsaicin results in increased secretion of CXCL8 protein]; Ruthenium Red inhibits the reaction [Capsaicin results in increased expression of CXCL8 mRNA]
Capsaicin affects the expression of CXCL8 mRNA
Capsaicin results in decreased expression of CXCL8 protein		 CTD PMID:12034025 PMID:16173059 PMID:17760719 PMID:20619260 PMID:21745629 More... NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of CXCL2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCL2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCL2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCL2 protein]		 CTD PMID:22150557 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797 		JBrowse link
G Cxcl5 C-X-C motif chemokine ligand 5 multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCL5 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCL5 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCL5 protein] CTD PMID:22150557 NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of CXCR4 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of CXCR4 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of CXCR4 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of CXCR4 protein]		 CTD PMID:22150557 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Cybb cytochrome b-245, beta polypeptide multiple interactions EXP
ISO		 CYBB protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]
CYBB mutant form inhibits the reaction [Capsaicin results in increased expression of STAT1 protein]		 CTD PMID:18203709 PMID:20712533 NCBI chr  X:9,301,493...9,354,005
Ensembl chr  X:9,301,491...9,354,010 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
affects expression		 EXP [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Capsaicin affects the expression of and affects the activity of CYP1A1 protein; Capsaicin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]
Capsaicin affects the expression of CYP1A1 mRNA		 CTD PMID:19449198 PMID:21250977 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Capsaicin results in decreased activity of CYP1A2 protein CTD PMID:22375877 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 decreases activity ISO Capsaicin results in decreased activity of CYP2C19 protein CTD PMID:22375877 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 decreases activity ISO Capsaicin results in decreased activity of CYP2C9 protein CTD PMID:22375877 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388 		JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 decreases activity ISO Capsaicin results in decreased activity of CYP2D6 protein CTD PMID:22375877 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression ISO Capsaicin results in increased expression of CYP2E1 CTD PMID:22375877 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Dap death-associated protein increases expression ISO Capsaicin results in increased expression of DAP mRNA CTD PMID:36044967 NCBI chr15:31,224,531...31,274,484
Ensembl chr15:31,224,460...31,274,487 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
affects localization		 ISO Capsaicin results in increased expression of DDIT3 protein
Capsaicin analog results in increased expression of DDIT3 mRNA; Capsaicin results in increased expression of DDIT3; Capsaicin results in increased expression of DDIT3 mRNA; Capsaicin results in increased expression of DDIT3 protein
Capsaicin affects the localization of DDIT3 protein		 CTD PMID:18533110 PMID:19139269 PMID:19285962 PMID:19331147 PMID:19699254 More... NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Defb2 defensin beta 2 multiple interactions
increases expression		 ISO Glyoxal promotes the reaction [Capsaicin results in increased expression of DEFB2 protein] CTD PMID:29496360 NCBI chr 8:22,329,942...22,333,519
Ensembl chr 8:22,329,942...22,333,498 		JBrowse link
G Depp1 DEPP1 autophagy regulator increases expression ISO Capsaicin results in increased expression of DEPP1 mRNA CTD PMID:36044967 NCBI chr 6:116,627,645...116,629,808
Ensembl chr 6:116,627,570...116,629,755 		JBrowse link
G Dffa DNA fragmentation factor, alpha subunit decreases expression ISO Capsaicin results in decreased expression of DFFA CTD PMID:16188123 NCBI chr 4:149,188,599...149,205,110
Ensembl chr 4:149,188,603...149,205,104 		JBrowse link
G Dpp3 dipeptidylpeptidase 3 decreases expression ISO Capsaicin results in decreased expression of DPP3 mRNA CTD PMID:20349343 NCBI chr19:4,957,257...4,978,315
Ensembl chr19:4,957,257...4,978,315 		JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO [NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]] which results in increased expression of DUSP1 protein; DUSP1 mutant form promotes the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased secretion of CXCL8 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased secretion of IL6 protein] CTD PMID:22171160 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102 		JBrowse link
G E2f1 E2F transcription factor 1 increases expression ISO Capsaicin results in increased expression of E2F1 mRNA CTD PMID:19502594 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812 		JBrowse link
G Edn1 endothelin 1 multiple interactions
decreases activity		 ISO EDN1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; FR 139317 inhibits the reaction [EDN1 protein results in decreased activity of Capsaicin] CTD PMID:9932722 PMID:19429182 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions ISO Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of EEF2 protein] CTD PMID:20359164 NCBI chr10:81,012,465...81,018,343
Ensembl chr10:81,012,465...81,018,332 		JBrowse link
G Egf epidermal growth factor multiple interactions
decreases activity
decreases expression		 ISO Capsaicin inhibits the reaction [EGF results in increased activity of MMP2 protein]; Capsaicin inhibits the reaction [EGF results in increased activity of MMP9 protein]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP14]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP2]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP9]; Capsaicin inhibits the reaction [EGF results in increased localization of FOS protein]; Capsaicin inhibits the reaction [EGF results in increased localization of JUN protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of AKT1 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of EGFR protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK3 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK8 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK9 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of PTK2 protein]
Capsaicin results in decreased activity of EGF protein
Capsaicin results in decreased expression of EGF protein		 CTD PMID:9324159 PMID:14521749 PMID:21462327 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases expression
increases phosphorylation		 ISO
EXP		 AG 1879 inhibits the reaction [Capsaicin results in increased phosphorylation of EGFR protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of EGFR protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Capsaicin results in increased phosphorylation of EGFR protein]; RTKI cpd inhibits the reaction [Capsaicin results in increased phosphorylation of EGFR protein]
Capsaicin results in decreased expression of EGFR protein
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; EGFR gene mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]		 CTD PMID:14521749 PMID:19855437 PMID:20619260 PMID:20660715 PMID:21462327 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Egr1 early growth response 1 increases expression ISO Capsaicin results in increased expression of EGR1 mRNA CTD PMID:20349343 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO Capsaicin results in increased phosphorylation of EIF2A protein CTD PMID:18533110 PMID:19285962 NCBI chr 3:58,433,252...58,464,922
Ensembl chr 3:58,433,242...58,464,922 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha increases phosphorylation ISO Capsaicin results in increased phosphorylation of EIF2S1 protein CTD PMID:19139269 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784 		JBrowse link
G Eln elastin increases expression ISO Capsaicin results in increased expression of ELN mRNA CTD PMID:16278290 NCBI chr 5:134,731,449...134,776,300
Ensembl chr 5:134,731,447...134,776,177 		JBrowse link
G Eno2 enolase 2, gamma neuronal multiple interactions EXP Capsaicin inhibits the reaction [Benzo(a)pyrene results in increased expression of ENO2 protein] CTD PMID:19449198 NCBI chr 6:124,737,018...124,746,489
Ensembl chr 6:124,737,016...124,746,636 		JBrowse link
G Enox2 ecto-NOX disulfide-thiol exchanger 2 increases response to substance ISO ENOX2 results in increased susceptibility to Capsaicin CTD PMID:15706060 NCBI chr  X:48,098,584...48,377,126
Ensembl chr  X:48,098,584...48,377,136 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; 3-(2-methoxybenzylamino)-2-phenylpiperidine inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; [[Capsaicin results in increased chemical synthesis of Lysophosphatidylcholines] which results in increased secretion of Lysophosphatidylcholines] promotes the reaction [ENPP2 results in increased chemical synthesis of lysophosphatidic acid]; [ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid; arachidonyltrifluoromethane inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; bisindolylmaleimide I inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; Dizocilpine Maleate inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; U 0126 inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; xestospongin C inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid] CTD PMID:19014389 NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288 		JBrowse link
G Epor erythropoietin receptor increases expression EXP Capsaicin results in increased expression of EPOR mRNA; Capsaicin results in increased expression of EPOR protein CTD PMID:17603282 NCBI chr 9:21,870,193...21,874,915
Ensembl chr 9:21,870,193...21,874,802 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects expression
decreases expression		 ISO Capsaicin affects the expression of ERBB2 mRNA
Capsaicin results in decreased expression of ERBB2 protein		 CTD PMID:19502594 PMID:19855437 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 increases expression ISO Capsaicin results in increased expression of ERN1 protein CTD PMID:19139269 PMID:19699254 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of ERRFI1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of ERRFI1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of ERRFI1 protein] CTD PMID:22150557 NCBI chr 4:150,938,253...150,953,346
Ensembl chr 4:150,938,376...150,953,349 		JBrowse link
G Etfa electron transferring flavoprotein, alpha polypeptide multiple interactions ISO Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of ETFA protein] CTD PMID:20359164 NCBI chr 9:55,361,720...55,419,528
Ensembl chr 9:55,361,792...55,419,527 		JBrowse link
G Exosc8 exosome component 8 decreases expression ISO Capsaicin results in decreased expression of EXOSC8 mRNA CTD PMID:16278290 NCBI chr 3:54,636,099...54,642,469
Ensembl chr 3:54,636,099...54,642,814 		JBrowse link
G F2 coagulation factor II affects expression ISO Capsaicin affects the expression of F2 protein CTD PMID:8285224 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] CTD PMID:16793902 NCBI chr13:95,648,226...95,661,748
Ensembl chr13:95,648,240...95,661,735 		JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte decreases expression
multiple interactions		 ISO Capsaicin results in decreased expression of FABP4 mRNA
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of FABP4 mRNA]; Capsaicin inhibits the reaction [Dietary Fats results in increased expression of FABP4 protein]		 CTD PMID:18533110 PMID:20359164 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636 		JBrowse link
G Fabp5 fatty acid binding protein 5, epidermal decreases expression ISO Capsaicin results in decreased expression of FABP5 mRNA CTD PMID:18533110 NCBI chr 3:10,077,645...10,081,670
Ensembl chr 3:10,077,608...10,081,667 		JBrowse link
G Fadd Fas associated via death domain increases expression
multiple interactions		 ISO Capsaicin results in increased expression of FADD protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FADD protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FADD protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FADD protein]		 CTD PMID:22150557 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200 		JBrowse link
G Fam162a family with sequence similarity 162, member A decreases expression ISO Capsaicin results in decreased expression of FAM162A mRNA CTD PMID:16278290 NCBI chr16:35,864,214...35,891,931
Ensembl chr16:35,864,131...35,891,964 		JBrowse link
G Fas Fas cell surface death receptor increases expression
affects expression
multiple interactions		 ISO Capsaicin results in increased expression of FAS mRNA; Capsaicin results in increased expression of FAS protein
Capsaicin affects the expression of FAS mRNA
Capsaicin promotes the reaction [resveratrol results in increased expression of FAS protein]
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FAS protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FAS protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FAS protein]		 CTD PMID:19502594 PMID:19846903 PMID:21310942 PMID:22150557 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fasl Fas ligand multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FASLG protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FASLG protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FASLG protein] CTD PMID:22150557 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 increases expression ISO Capsaicin results in increased expression of FBXL2 mRNA CTD PMID:36044967 NCBI chr 9:113,787,625...113,855,871
Ensembl chr 9:113,792,705...113,875,259 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Capsaicin results in increased expression of FDFT1 mRNA CTD PMID:33512557 NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027 		JBrowse link
G Fdps farnesyl diphosphate synthetase increases expression ISO Capsaicin results in increased expression of FDPS mRNA CTD PMID:16278290 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266 		JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Capsaicin results in decreased expression of FGF2 protein CTD PMID:14521749 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257 		JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 multiple interactions
affects expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of FGFBP1 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of FGFBP1 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of FGFBP1 protein] CTD PMID:22150557 NCBI chr 5:44,136,200...44,139,173
Ensembl chr 5:44,136,200...44,139,121 		JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 decreases expression ISO Capsaicin results in decreased expression of FGFR1 protein CTD PMID:14521749 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734 		JBrowse link
G Fgl1 fibrinogen-like protein 1 multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FGL1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FGL1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FGL1 protein] CTD PMID:22150557 NCBI chr 8:41,644,471...41,671,015
Ensembl chr 8:41,644,471...41,668,193 		JBrowse link
G Fkbp4 FK506 binding protein 4 decreases expression ISO Capsaicin results in decreased expression of FKBP4 mRNA CTD PMID:20349343 NCBI chr 6:128,407,066...128,415,619
Ensembl chr 6:128,406,698...128,415,640 		JBrowse link
G Flcn folliculin increases expression ISO Capsaicin results in increased expression of FLCN mRNA CTD PMID:36044967 NCBI chr11:59,682,234...59,706,138
Ensembl chr11:59,682,234...59,700,842 		JBrowse link
G Fmod fibromodulin increases expression ISO Capsaicin results in increased expression of FMOD mRNA CTD PMID:20349343 NCBI chr 1:133,964,992...133,976,018
Ensembl chr 1:133,964,992...133,976,015 		JBrowse link
G Fnta farnesyltransferase, CAAX box, alpha increases expression ISO Capsaicin results in increased expression of FNTA mRNA CTD PMID:16278290 NCBI chr 8:26,488,716...26,505,638
Ensembl chr 8:26,488,750...26,505,678 		JBrowse link
G Fos FBJ osteosarcoma oncogene decreases expression
multiple interactions
increases expression		 ISO
EXP		 Capsaicin results in decreased expression of FOS mRNA
Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS mRNA]; Dextran Sulfate promotes the reaction [Capsaicin results in increased expression of FOS protein]; GHRL protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]; GRK6 mutant form promotes the reaction [Dextran Sulfate promotes the reaction [Capsaicin results in increased expression of FOS protein]]; HTR1B protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]; HTR1D protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]; HTR1F protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]; LY 344864 inhibits the reaction [Capsaicin results in increased expression of FOS protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FOS protein]
Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; Capsaicin inhibits the reaction [EGF results in increased localization of FOS protein]
2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline inhibits the reaction [Capsaicin results in increased expression of FOS]; 2-amino-4-phosphonobutyric acid inhibits the reaction [Capsaicin results in increased expression of FOS]; 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased expression of FOS]; Capsaicin inhibits the reaction [8-sulfocholecystokinin octapeptide results in increased expression of FOS protein]; Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]; Capsaicin inhibits the reaction [GHRL results in increased expression of FOS protein]; Capsaicin inhibits the reaction [Hydrochloric Acid results in increased expression of FOS protein]; Melatonin inhibits the reaction [Capsaicin results in increased expression of FOS protein]
Capsaicin results in increased expression of FOS; Capsaicin results in increased expression of FOS mRNA; Capsaicin results in increased expression of FOS protein		 CTD PMID:1922926 PMID:9372230 PMID:9580328 PMID:10401552 PMID:10749792 More... NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Fosl1 fos-like antigen 1 multiple interactions
increases expression		 ISO N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Capsaicin results in increased expression of FOSL1 protein] CTD PMID:20054487 NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974 		JBrowse link
G Foxa1 forkhead box A1 decreases expression ISO Capsaicin results in decreased expression of FOXA1 mRNA CTD PMID:18533110 NCBI chr12:57,585,750...57,594,815
Ensembl chr12:57,587,414...57,593,702 		JBrowse link
G Foxe3 forkhead box E3 increases expression ISO Capsaicin results in increased expression of FOXE3 mRNA CTD PMID:16278290 NCBI chr 4:114,781,640...114,783,264
Ensembl chr 4:114,782,344...114,783,210 		JBrowse link
G Fstl1 follistatin-like 1 multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of FSTL1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of FSTL1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of FSTL1 protein] CTD PMID:22150557 NCBI chr16:37,597,417...37,656,878
Ensembl chr16:37,597,235...37,656,876 		JBrowse link
G Fxyd6 FXYD domain-containing ion transport regulator 6 increases expression ISO Capsaicin results in increased expression of FXYD6 mRNA CTD PMID:16278290 NCBI chr 9:45,280,768...45,307,457
Ensembl chr 9:45,281,483...45,307,457 		JBrowse link
G Gabrr3 gamma-aminobutyric acid type A receptor subunit rho 3 increases expression ISO Capsaicin results in increased expression of GABRR3 mRNA CTD PMID:16278290 NCBI chr16:59,227,745...59,282,102
Ensembl chr16:59,227,695...59,284,867 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha increases expression ISO Capsaicin results in increased expression of GADD45A mRNA CTD PMID:19502594 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441 		JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions
decreases response to substance
increases expression		 ISO
EXP		 GAL protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]
GAL protein results in decreased susceptibility to Capsaicin
Capsaicin results in increased expression of GAL mRNA		 CTD PMID:8971780 PMID:17999197 PMID:18553211 PMID:19112407 NCBI chr19:3,459,915...3,464,544
Ensembl chr19:3,459,915...3,464,544 		JBrowse link
G Galr2 galanin receptor 2 increases expression ISO Capsaicin results in increased expression of GALR2 mRNA CTD PMID:18553211 NCBI chr11:116,170,520...116,174,776
Ensembl chr11:116,171,765...116,174,764 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions
increases expression		 ISO Capsaicin inhibits the reaction [Dietary Fats results in increased expression of GAPDH protein]
Capsaicin results in increased expression of GAPDH protein		 CTD PMID:18991268 PMID:20359164 NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430 		JBrowse link
G Gast gastrin increases secretion
decreases secretion		 ISO Capsaicin results in increased secretion of GAST protein
Capsaicin results in decreased secretion of GAST protein		 CTD PMID:8093880 PMID:19208342 PMID:19296048 NCBI chr11:100,225,233...100,227,823
Ensembl chr11:100,225,233...100,227,822 		JBrowse link
G Gata1 GATA binding protein 1 increases expression EXP Capsaicin results in increased expression of GATA1 mRNA CTD PMID:17603282 NCBI chr  X:7,825,504...7,842,844
Ensembl chr  X:7,825,499...7,844,310 		JBrowse link
G Gcg glucagon multiple interactions EXP Capsaicin inhibits the reaction [Deoxyglucose results in increased secretion of GCG protein] CTD PMID:1378463 NCBI chr 2:62,304,874...62,313,997
Ensembl chr 2:62,304,874...62,313,994 		JBrowse link
G Gch1 GTP cyclohydrolase 1 affects response to substance ISO GCH1 gene SNP affects the susceptibility to Capsaicin CTD PMID:19081190 NCBI chr14:47,391,352...47,426,870
Ensembl chr14:47,391,352...47,426,870 		JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions
increases expression
increases phosphorylation		 ISO [CEBPB protein binds to GDF15 promoter] promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA]; ATF3 mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]; CEBPB mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]; CEBPB protein promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA]; GSK3B mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA]
Capsaicin results in increased phosphorylation of GDF15 protein		 CTD PMID:20110283 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions		 ISO Capsaicin results in increased expression of GFAP mRNA
7-nitroindazole inhibits the reaction [Capsaicin results in increased expression of GFAP protein]; [7-nitroindazole co-treated with pimagedine] promotes the reaction [Capsaicin results in increased expression of GFAP protein]; Capsaicin inhibits the reaction [IL6 protein results in increased expression of GFAP mRNA]; capsazepine inhibits the reaction [Capsaicin results in increased expression of GFAP protein]; pimagedine inhibits the reaction [Capsaicin results in increased expression of GFAP protein]		 CTD PMID:18405923 PMID:19285962 PMID:20826152 NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738 		JBrowse link
G Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 affects expression
multiple interactions		 ISO Capsaicin affects the expression of GFRA1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of GFRA1 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of GFRA1 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of GFRA1 protein]		 CTD PMID:22150557 NCBI chr19:58,224,013...58,444,387
Ensembl chr19:58,224,036...58,444,341 		JBrowse link
G Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 affects expression
multiple interactions		 ISO Capsaicin affects the expression of GFRA2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of GFRA2 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of GFRA2 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of GFRA2 protein]		 CTD PMID:22150557 NCBI chr14:71,127,547...71,217,280
Ensembl chr14:71,127,560...71,217,278 		JBrowse link
G Gh growth hormone decreases secretion
multiple interactions
increases expression		 ISO Capsaicin results in decreased secretion of GH protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of GH1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of GH1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of GH1 protein]		 CTD PMID:12360474 PMID:22150557 NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691 		JBrowse link
G Ghr growth hormone receptor increases expression
multiple interactions		 ISO Capsaicin results in increased expression of GHR protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of GHR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of GHR protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of GHR protein]		 CTD PMID:22150557 NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974 		JBrowse link
G Ghrl ghrelin multiple interactions
decreases activity		 EXP
ISO		 GHRL protein inhibits the reaction [Capsaicin results in increased expression of FOS protein]
Capsaicin inhibits the reaction [GHRL results in increased expression of FOS protein]
Capsaicin results in decreased activity of GHRL protein		 CTD PMID:12360474 PMID:15177919 PMID:18202139 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841 		JBrowse link
G Gjb6 gap junction protein, beta 6 increases expression ISO Capsaicin results in increased expression of GJB6 mRNA CTD PMID:20349343 NCBI chr14:57,360,760...57,370,764
Ensembl chr14:57,360,760...57,371,068 		JBrowse link
G Glp1r glucagon-like peptide 1 receptor decreases expression ISO Capsaicin results in decreased expression of GLP1R mRNA CTD PMID:22031786 NCBI chr17:31,120,841...31,155,484
Ensembl chr17:31,120,791...31,159,765 		JBrowse link
G Glud1 glutamate dehydrogenase 1 increases expression ISO Capsaicin results in increased expression of GLUD1 protein CTD PMID:18991268 NCBI chr14:34,032,684...34,066,990
Ensembl chr14:34,032,684...34,067,222 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble multiple interactions ISO Capsaicin inhibits the reaction [ferric sulfate results in increased activity of GOT1 protein]; Capsaicin inhibits the reaction [Iron results in increased activity of GOT1 protein] CTD PMID:16956363 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044 		JBrowse link
G Gpr132 G protein-coupled receptor 132 decreases expression EXP Capsaicin results in decreased expression of GPR132 mRNA CTD PMID:19602228 NCBI chr12:112,814,493...112,832,035
Ensembl chr12:112,814,493...112,831,848 		JBrowse link
G Gpr176 G protein-coupled receptor 176 decreases expression ISO Capsaicin results in decreased expression of GPR176 mRNA CTD PMID:16278290 NCBI chr 2:118,107,577...118,205,022
Ensembl chr 2:118,107,591...118,203,900 		JBrowse link
G Gpr4 G protein-coupled receptor 4 decreases expression EXP Capsaicin results in decreased expression of GPR4 mRNA CTD PMID:19602228 NCBI chr 7:18,946,463...18,958,101
Ensembl chr 7:18,946,463...18,958,099 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO Capsaicin inhibits the reaction [ferric sulfate results in increased activity of GPT protein]; Capsaicin inhibits the reaction [Iron results in increased activity of GPT protein] CTD PMID:16956363 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP Capsaicin inhibits the reaction [Ethanol results in decreased expression of GPX1 mRNA] CTD PMID:18926900 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions EXP Capsaicin inhibits the reaction [Ethanol results in decreased expression of GPX4 mRNA] CTD PMID:18926900 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273 		JBrowse link
G Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) increases phosphorylation
multiple interactions		 ISO Capsaicin results in increased phosphorylation of GRIA1 protein
KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of GRIA1 protein]		 CTD PMID:12019337 NCBI chr11:56,902,342...57,221,070
Ensembl chr11:56,902,213...57,221,070 		JBrowse link
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) multiple interactions
increases expression
increases phosphorylation		 ISO N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Capsaicin results in increased phosphorylation of GRIN1 protein]; phenyl-N-tert-butylnitrone inhibits the reaction [Capsaicin results in increased expression of GRIN1 protein modified form] CTD PMID:17317010 PMID:20054487 NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199 		JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) increases phosphorylation
multiple interactions		 ISO Capsaicin results in increased phosphorylation of GRIN2B protein
capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of GRIN2B protein]; Excitatory Amino Acid Antagonists inhibits the reaction [Capsaicin results in increased phosphorylation of GRIN2B protein]		 CTD PMID:18577691 NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 multiple interactions
decreases response to substance		 EXP GRK6 mutant form promotes the reaction [Dextran Sulfate promotes the reaction [Capsaicin results in increased expression of FOS protein]]
GRK6 results in decreased susceptibility to Capsaicin		 CTD PMID:18687398 NCBI chr13:55,592,865...55,608,740
Ensembl chr13:55,592,885...55,608,740 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Capsaicin promotes the reaction [CEBPB protein binds to ATF3 protein binds to GSK3B protein]; GSK3B mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA] CTD PMID:20110283 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gsr glutathione reductase multiple interactions EXP Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased activity of GSR protein]; Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased expression of GSR] CTD PMID:18023135 PMID:18338764 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions ISO Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Capsaicin inhibits the reaction [TNF protein results in increased expression of GSTP1 mRNA] CTD PMID:15313406 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Gtf2h2 general transcription factor II H, polypeptide 2 decreases expression ISO Capsaicin results in decreased expression of GTF2H2 mRNA CTD PMID:16278290 NCBI chr13:100,596,726...100,629,123
Ensembl chr13:100,596,726...100,629,087 		JBrowse link
G Gypa glycophorin A increases expression EXP Capsaicin results in increased expression of GYPA mRNA CTD PMID:17603282 NCBI chr 8:81,220,674...81,237,414
Ensembl chr 8:81,220,410...81,237,171 		JBrowse link
G Gzma granzyme A multiple interactions
increases expression		 ISO Capsaicin results in increased expression of and results in increased secretion of GZMA protein
Capsaicin results in increased expression of GZMA mRNA		 CTD PMID:21310942 NCBI chr13:113,230,358...113,237,515
Ensembl chr13:113,230,359...113,237,515 		JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 multiple interactions EXP Capsaicin inhibits the reaction [IFNG protein results in increased expression of H2-AB1 mRNA] CTD PMID:19825429 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393 		JBrowse link
G H2ax H2A.X variant histone increases localization ISO Capsaicin results in increased localization of H2AX protein CTD PMID:22226932 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G H2bc1 H2B clustered histone 1 decreases expression ISO Capsaicin results in decreased expression of H2BC1 mRNA CTD PMID:16278290 NCBI chr13:24,117,708...24,118,139
Ensembl chr13:24,117,756...24,118,139 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) multiple interactions EXP Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased activity of H6PD protein] CTD PMID:18338764 NCBI chr 4:150,063,931...150,093,480
Ensembl chr 4:150,063,932...150,093,480 		JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain increases expression EXP Capsaicin results in increased expression of HBB-B1 mRNA CTD PMID:17603282
G Hbb-bh1 hemoglobin Z, beta-like embryonic chain multiple interactions ISO Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of HBG1 protein] CTD PMID:20359164 NCBI chr 7:103,490,845...103,492,369
Ensembl chr 7:103,490,844...103,492,371 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions EXP [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of HBEGF mRNA CTD PMID:20660715 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858 		JBrowse link
G Hcrt hypocretin multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of HCRT protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of HCRT protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of HCRT protein] CTD PMID:22150557 NCBI chr11:100,652,519...100,653,757
Ensembl chr11:100,651,895...100,653,757 		JBrowse link
G Hdac2 histone deacetylase 2 increases expression ISO Capsaicin results in increased expression of HDAC2 mRNA CTD PMID:16278290 NCBI chr10:36,850,293...36,877,885
Ensembl chr10:36,850,540...36,877,885 		JBrowse link
G Hey2 hairy/enhancer-of-split related with YRPW motif 2 increases expression ISO Capsaicin results in increased expression of HEY2 mRNA CTD PMID:16278290 NCBI chr10:30,708,355...30,718,779
Ensembl chr10:30,708,355...30,718,797 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit increases expression ISO Capsaicin results in increased expression of HIF1A mRNA CTD PMID:12242509 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Hip1r huntingtin interacting protein 1 related decreases expression ISO Capsaicin results in decreased expression of HIP1R mRNA CTD PMID:20349343 NCBI chr 5:124,111,665...124,141,263
Ensembl chr 5:124,111,691...124,143,621 		JBrowse link
G Hmgb2 high mobility group box 2 increases expression ISO Capsaicin results in increased expression of HMGB2 mRNA CTD PMID:16278290 NCBI chr 8:57,964,877...57,969,033
Ensembl chr 8:57,964,941...57,969,033 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of HMOX1 mRNA; Capsaicin results in increased expression of HMOX1 protein
Capsaicin inhibits the reaction [monophosphoryl lipid A results in increased expression of HMOX1 mRNA]; Capsaicin promotes the reaction [Hydrochloric Acid results in increased expression of HMOX1 protein]
Acetylcysteine inhibits the reaction [Capsaicin results in increased expression of HMOX1 mRNA]		 CTD PMID:11738242 PMID:17979524 PMID:18617559 PMID:36044967 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression ISO Capsaicin results in increased expression of HNRNPA1 mRNA CTD PMID:20349343 NCBI chr15:103,148,840...103,155,119
Ensembl chr15:103,148,859...103,155,119 		JBrowse link
G Hpcal1 hippocalcin-like 1 increases expression ISO Capsaicin results in increased expression of HPCAL1 mRNA CTD PMID:16278290 NCBI chr12:17,740,810...17,841,943
Ensembl chr12:17,740,857...17,841,934 		JBrowse link
G Hras Harvey rat sarcoma virus oncogene increases expression ISO Capsaicin results in increased expression of HRAS mRNA CTD PMID:9461043 NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918 		JBrowse link
G Hsf1 heat shock factor 1 increases expression ISO Capsaicin results in increased expression of HSF1 mRNA CTD PMID:24746025 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113 		JBrowse link
G Hsp90b1 heat shock protein 90, beta (Grp94), member 1 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of HSP90B1 protein
Capsaicin inhibits the reaction [Dietary Fats results in increased expression of HSP90B1 protein]		 CTD PMID:18991268 PMID:20359164 NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373 		JBrowse link
G Hspa5 heat shock protein 5 increases expression
increases localization		 ISO Capsaicin results in increased expression of HSPA5; Capsaicin results in increased expression of HSPA5 protein
Capsaicin results in increased localization of HSPA5 protein		 CTD PMID:19139269 PMID:19331147 PMID:19699254 PMID:21859781 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hspb1 heat shock protein 1 multiple interactions ISO Capsaicin inhibits the reaction [Dietary Fats results in increased expression of HSP27 protein] CTD PMID:20359164 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417 		JBrowse link
G Htr1b 5-hydroxytryptamine (serotonin) receptor 1B multiple interactions EXP HTR1B protein inhibits the reaction [Capsaicin results in increased expression of FOS protein] CTD PMID:12110114 NCBI chr 9:81,510,344...81,515,885
Ensembl chr 9:81,510,344...81,515,881 		JBrowse link
G Htr1d 5-hydroxytryptamine (serotonin) receptor 1D multiple interactions EXP HTR1D protein inhibits the reaction [Capsaicin results in increased expression of FOS protein] CTD PMID:12110114 NCBI chr 4:136,150,835...136,171,716
Ensembl chr 4:136,150,835...136,171,709 		JBrowse link
G Htr1f 5-hydroxytryptamine (serotonin) receptor 1F multiple interactions EXP HTR1F protein inhibits the reaction [Capsaicin results in increased expression of FOS protein] CTD PMID:12110114 NCBI chr16:64,745,092...64,926,147
Ensembl chr16:64,745,092...64,926,217 		JBrowse link
G Htr3a 5-hydroxytryptamine (serotonin) receptor 3A decreases activity ISO Capsaicin results in decreased activity of HTR3A protein CTD PMID:26456648 NCBI chr 9:48,810,513...48,822,451
Ensembl chr 9:48,810,513...48,822,399 		JBrowse link
G Htr3b 5-hydroxytryptamine (serotonin) receptor 3B decreases expression ISO Capsaicin results in decreased expression of HTR3B mRNA CTD PMID:16278290 NCBI chr 9:48,846,308...48,876,290
Ensembl chr 9:48,846,308...48,876,290 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Capsaicin inhibits the reaction [Freund's Adjuvant results in increased expression of ICAM1] CTD PMID:20600813 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Ide insulin degrading enzyme multiple interactions
affects expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of IDE protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of IDE protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of IDE protein] CTD PMID:22150557 NCBI chr19:37,246,140...37,341,664
Ensembl chr19:37,246,142...37,340,010 		JBrowse link
G Ifng interferon gamma decreases expression
multiple interactions		 EXP
ISO		 Capsaicin results in decreased expression of IFNG
Capsaicin results in decreased expression of IFNG protein
[Capsaicin results in increased susceptibility to Glyoxal] which results in increased expression of IFNG mRNA; [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in decreased expression of IFNG protein]; Naproxen inhibits the reaction [Capsaicin results in decreased expression of IFNG protein]; Sumatriptan inhibits the reaction [Capsaicin results in decreased expression of IFNG protein]
Capsaicin inhibits the reaction [[IFNG protein results in increased abundance of Nitric Oxide] which results in increased expression of NOS2 protein]; Capsaicin inhibits the reaction [IFNG protein results in increased abundance of Nitric Oxide]; Capsaicin inhibits the reaction [IFNG protein results in increased expression of CIITA mRNA]; Capsaicin inhibits the reaction [IFNG protein results in increased expression of H2-AB1 mRNA]; Capsaicin inhibits the reaction [IFNG results in increased activity of STAT1 protein]; Capsaicin inhibits the reaction [IFNG results in increased expression of NOS2 protein]		 CTD PMID:14530214 PMID:17306834 PMID:19825429 PMID:22150557 PMID:29496360 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
increases expression		 EXP
ISO		 CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 mRNA]; CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 protein]; Isoflavones promotes the reaction [Capsaicin results in increased expression of IGF1 protein]
capsazepine inhibits the reaction [Capsaicin results in increased expression of IGF1 protein]
Capsaicin results in increased expression of IGF1 mRNA; Capsaicin results in increased expression of IGF1 protein
[Capsaicin co-treated with Isoflavones] results in increased expression of IGF1 protein; TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1 mRNA]		 CTD PMID:17307377 PMID:17569567 PMID:17693108 PMID:19502719 PMID:21310942 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904 		JBrowse link
G Igf1r insulin-like growth factor I receptor increases expression
multiple interactions		 ISO Capsaicin results in increased expression of IGF1R mRNA
TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1R mRNA]		 CTD PMID:21310942 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Igf2 insulin-like growth factor 2 increases expression ISO Capsaicin results in increased expression of IGF2 mRNA CTD PMID:20349343 NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553 		JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression		 EXP
ISO		 Capsaicin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]]
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL10 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL10 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL10 protein]
Capsaicin results in increased expression of IL10 mRNA; Capsaicin results in increased expression of IL10 protein		 CTD PMID:15502055 PMID:18460982 PMID:19878665 PMID:22150557 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 decreases expression ISO Capsaicin results in decreased expression of IL11RA1 mRNA CTD PMID:16278290 NCBI chr 4:41,760,443...41,769,473
Ensembl chr 4:41,699,989...41,769,474 		JBrowse link
G Il12b interleukin 12b decreases expression ISO Capsaicin results in decreased expression of IL12B mRNA CTD PMID:18533110 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860 		JBrowse link
G Il13 interleukin 13 multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL13 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL13 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL13 protein] CTD PMID:22150557 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions
decreases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]; Naproxen inhibits the reaction [Capsaicin results in decreased expression of IL1A protein]; Sumatriptan inhibits the reaction [Capsaicin results in decreased expression of IL1A protein] CTD PMID:22150557 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta decreases secretion
multiple interactions
affects expression
increases expression
increases response to substance		 ISO
EXP		 Capsaicin results in decreased secretion of IL1B protein
Capsaicin inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Capsaicin inhibits the reaction [IL1B protein results in increased expression of CXCL8 protein]; Capsaicin promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]
Capsaicin affects the expression of IL1B protein
Capsaicin results in increased expression of IL1B mRNA; Capsaicin results in increased expression of IL1B protein
[Capsaicin results in increased susceptibility to Formaldehyde] which results in increased expression of IL1B mRNA; [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of IL1B protein]; Capsaicin inhibits the reaction [Ibotenic Acid results in increased expression of IL1B protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of IL1B protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of IL1B protein]; spantide II inhibits the reaction [Capsaicin results in increased expression of IL1B protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of IL1B protein]
IL1B gene SNP results in increased susceptibility to Capsaicin		 CTD PMID:12034025 PMID:15265675 PMID:18769453 PMID:19878665 PMID:22150557 More... NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO IL1RN protein inhibits the reaction [Nicotine results in increased activity of Capsaicin] CTD PMID:27180639 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Il2 interleukin 2 decreases expression
increases expression
multiple interactions		 EXP
ISO		 Capsaicin results in decreased expression of IL2
Capsaicin results in increased expression of IL2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL2 protein]		 CTD PMID:17306834 PMID:22150557 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il3 interleukin 3 multiple interactions
affects expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of IL3 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of IL3 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of IL3 protein] CTD PMID:22150557 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103 		JBrowse link
G Il4 interleukin 4 decreases expression
multiple interactions
increases expression		 EXP
ISO		 Capsaicin results in decreased expression of IL4
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL4 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL4 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL4 protein]
Capsaicin results in increased expression of IL4 mRNA; Capsaicin results in increased expression of IL4 protein		 CTD PMID:17306834 PMID:22150557 PMID:29496360 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il5 interleukin 5 decreases expression
increases expression
multiple interactions		 EXP
ISO		 Capsaicin results in decreased expression of IL5
Capsaicin results in increased expression of IL5 mRNA; Capsaicin results in increased expression of IL5 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL5 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL5 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL5 protein]		 CTD PMID:17306834 PMID:22150557 PMID:29496360 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
increases expression
decreases secretion
increases secretion		 ISO
EXP		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; 7-oxozeanol inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; bisindolylmaleimide inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]; Capsaicin promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; capsazepine inhibits the reaction [Capsaicin results in increased expression of IL6 mRNA]; capsazepine inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased secretion of IL6 protein]; Egtazic Acid inhibits the reaction [Capsaicin results in increased expression of IL6 mRNA]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; RTKI cpd affects the reaction [Capsaicin results in increased secretion of IL6 protein]; Ruthenium Red inhibits the reaction [Capsaicin results in increased expression of IL6 mRNA]; TRPV1 protein promotes the reaction [Capsaicin results in increased expression of IL6 mRNA]; TRPV1 protein promotes the reaction [Capsaicin results in increased expression of IL6 protein]
Capsaicin results in decreased expression of IL6 mRNA; Capsaicin results in decreased expression of IL6 protein
capsazepine inhibits the reaction [Capsaicin results in decreased secretion of IL6 protein]; troglitazone promotes the reaction [Capsaicin results in decreased secretion of IL6 protein]
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Capsaicin inhibits the reaction [Ibotenic Acid results in increased expression of IL6 protein]; Capsaicin inhibits the reaction [IL6 protein results in increased expression of GFAP mRNA]; Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; Ketotifen inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; spantide II inhibits the reaction [Capsaicin results in increased expression of IL6 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of IL6 protein]
Capsaicin results in increased expression of IL6 mRNA; Capsaicin results in increased expression of IL6 protein		 CTD PMID:15265675 PMID:15502055 PMID:16173059 PMID:17306835 PMID:17505005 More... NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Il6st interleukin 6 signal transducer decreases expression ISO Capsaicin results in decreased expression of IL6ST protein CTD PMID:19285962 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620 		JBrowse link
G Il7 interleukin 7 decreases expression ISO Capsaicin results in decreased expression of IL7 mRNA CTD PMID:16278290 NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820 		JBrowse link
G Inhba inhibin beta-A increases expression
multiple interactions		 ISO Capsaicin results in increased expression of INHBA protein
Capsaicin inhibits the reaction [Ibotenic Acid results in increased expression of INHBA protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of INHBA protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of INHBA protein]		 CTD PMID:22150557 PMID:36925032 NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206 		JBrowse link
G Ins1 insulin I decreases expression
multiple interactions
increases expression
affects response to substance		 EXP
ISO		 Capsaicin results in decreased expression of INS1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of INS1 protein]; Capsaicin promotes the reaction [Glucose results in increased secretion of INS1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of INS1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of INS1 protein]
Capsaicin affects the susceptibility to INS1 protein		 CTD PMID:16322403 PMID:17241282 PMID:19798065 PMID:22150557 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914 		JBrowse link
G Ins2 insulin II multiple interactions ISO [INS protein co-treated with Capsaicin] promotes the reaction [Capsaicin results in increased uptake of cobaltous chloride] CTD PMID:14622148 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Irs1 insulin receptor substrate 1 increases expression EXP Capsaicin results in increased expression of IRS1 mRNA CTD PMID:19798065 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137 		JBrowse link
G Itga5 integrin alpha 5 (fibronectin receptor alpha) increases expression ISO Capsaicin results in increased expression of ITGA5 mRNA CTD PMID:16278290 NCBI chr15:103,252,713...103,275,218
Ensembl chr15:103,252,713...103,275,190 		JBrowse link
G Jak1 Janus kinase 1 multiple interactions ISO Capsaicin results in decreased phosphorylation of and results in decreased activity of JAK1 protein CTD PMID:17505005 NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479 		JBrowse link
G Jun jun proto-oncogene decreases expression
multiple interactions
increases expression		 ISO Capsaicin results in decreased expression of JUN mRNA
[Capsaicin results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; Capsaicin inhibits the reaction [EGF results in increased localization of JUN protein]
Capsaicin results in increased expression of JUN mRNA		 CTD PMID:1922926 PMID:9580328 PMID:17292493 PMID:19502594 PMID:21462327 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Jund jun D proto-oncogene increases expression ISO Capsaicin results in increased expression of JUND mRNA CTD PMID:16278290 NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265 		JBrowse link
G Kcnq4 potassium voltage-gated channel, subfamily Q, member 4 increases expression ISO Capsaicin results in increased expression of KCNQ4 mRNA CTD PMID:16278290 NCBI chr 4:120,553,331...120,605,809
Ensembl chr 4:120,553,335...120,605,809 		JBrowse link
G Kif11 kinesin family member 11 increases expression ISO Capsaicin results in increased expression of KIF11 mRNA CTD PMID:16278290 NCBI chr19:37,364,830...37,410,311
Ensembl chr19:37,364,851...37,410,307 		JBrowse link
G Klf1 Kruppel-like transcription factor 1 (erythroid) increases expression EXP Capsaicin results in increased expression of KLF1 mRNA CTD PMID:17603282 NCBI chr 8:85,628,611...85,631,920
Ensembl chr 8:85,628,557...85,631,924 		JBrowse link
G Klf4 Kruppel-like transcription factor 4 (gut) increases expression ISO Capsaicin results in increased expression of KLF4 mRNA CTD PMID:20349343 NCBI chr 4:55,527,137...55,536,984
Ensembl chr 4:55,527,143...55,532,466 		JBrowse link
G Klk6 kallikrein related-peptidase 6 increases expression ISO Capsaicin results in increased expression of KLK6 mRNA CTD PMID:20349343 NCBI chr 7:43,473,967...43,481,219
Ensembl chr 7:43,473,923...43,481,454 		JBrowse link
G Kng1 kininogen 1 multiple interactions
affects activity
increases response to substance		 ISO
EXP		 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [KNG1 protein results in increased susceptibility to Capsaicin]; 2-aminoethyl diphenylborinate inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Capsaicin inhibits the reaction [[KNG1 protein alternative form binds to and results in increased activity of BDKRB2 protein] which results in increased abundance of Inositol Phosphates]; Capsaicin promotes the reaction [Nicotine results in decreased activity of KNG1 protein alternative form]; HU 211 inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Indomethacin inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; U 73343 promotes the reaction [KNG1 protein results in increased susceptibility to Capsaicin]
KNG1 protein alternative form affects the reaction [P2RY2 protein affects the susceptibility to Capsaicin]
BDKRB2 affects the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]; KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]
Capsaicin affects the activity of KNG1 protein		 CTD PMID:7807204 PMID:10490893 PMID:15363968 PMID:15750287 PMID:16696851 More... NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828 		JBrowse link
G Lep leptin decreases expression
increases expression
multiple interactions		 EXP
ISO		 Capsaicin results in decreased expression of LEP protein
Capsaicin results in increased expression of LEP mRNA; Capsaicin results in increased expression of LEP protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of LEP protein]; Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of LEP mRNA]; Naproxen inhibits the reaction [Capsaicin results in increased expression of LEP protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of LEP protein]		 CTD PMID:16278290 PMID:17295509 PMID:19798065 PMID:20359164 PMID:22150557 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Lgals1 lectin, galactose binding, soluble 1 increases expression ISO Capsaicin results in increased expression of LGALS1 protein CTD PMID:18991268 NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665 		JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 multiple interactions
decreases expression
decreases response to substance		 EXP 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; [Capsaicin results in decreased expression of LRP1 protein] which results in decreased uptake of Cholesterol; [Capsaicin results in decreased expression of LRP1 protein] which results in increased secretion of Cholesterol; APOE affects the reaction [Capsaicin results in decreased expression of LRP1 protein]; Cyclosporine inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; KT 5720 inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]
LRP1 results in decreased susceptibility to Capsaicin		 CTD PMID:21908651 NCBI chr10:127,374,026...127,457,158
Ensembl chr10:127,374,030...127,457,017 		JBrowse link
G Ltb4r2 leukotriene B4 receptor 2 decreases expression ISO Capsaicin results in decreased expression of LTB4R2 mRNA CTD PMID:16278290 NCBI chr14:55,995,379...56,001,523
Ensembl chr14:55,998,885...56,002,595 		JBrowse link
G Ltf lactotransferrin increases expression ISO Capsaicin results in increased expression of LTF protein CTD PMID:9537786 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha multiple interactions
affects localization		 ISO acadesine promotes the reaction [Capsaicin affects the localization of MAP1LC3A protein]; dorsomorphin inhibits the reaction [Capsaicin affects the localization of MAP1LC3A protein] CTD PMID:36044967 NCBI chr 2:155,118,284...155,119,993
Ensembl chr 2:155,118,217...155,119,993 		JBrowse link
G Map2 microtubule-associated protein 2 increases expression ISO Capsaicin results in increased expression of MAP2 mRNA CTD PMID:18405923 NCBI chr 1:66,214,337...66,481,742
Ensembl chr 1:66,214,432...66,481,742 		JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 increases expression ISO Capsaicin results in increased expression of MAP2K1 mRNA CTD PMID:19502594 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913 		JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 multiple interactions ISO 7-oxozeanol inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAP3K7 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of MAP3K7 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAP3K7 protein] CTD PMID:22171160 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 decreases activity
increases activity
increases localization
increases expression
multiple interactions
increases phosphorylation		 ISO
EXP		 Capsaicin results in decreased activity of MAPK1 protein
Capsaicin results in increased activity of MAPK1 protein
Capsaicin results in increased localization of MAPK1 protein modified form
Capsaicin results in increased expression of MAPK1 protein modified form
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; 7-oxozeanol inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK1 protein]; Capsaicin results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; tricyclodecane-9-yl-xanthogenate inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK1 protein]; Capsaicin results in increased activity of and results in increased phosphorylation of MAPK1 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; 7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK1 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Dizocilpine Maleate inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; Genistein inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; Lidocaine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; SR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; staurosporine aglycone inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; substance P (6-11), Tyr(6)-D-Phe(7)-D-His(9)- inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Xenon inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]		 CTD PMID:12196597 PMID:12478662 PMID:12941468 PMID:14530214 PMID:15385614 More... NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK14 protein] CTD PMID:21745629 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Mapk15 mitogen-activated protein kinase 15 increases expression ISO Capsaicin results in increased expression of MAPK15 mRNA CTD PMID:36044967 NCBI chr15:75,865,581...75,871,002
Ensembl chr15:75,865,618...75,871,003 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases activity
increases activity
increases localization
increases expression
multiple interactions
increases phosphorylation		 ISO
EXP		 Capsaicin results in decreased activity of MAPK3 protein
Capsaicin results in increased activity of MAPK3 protein
Capsaicin results in increased localization of MAPK3 protein modified form
Capsaicin results in increased expression of MAPK3 protein modified form
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; 7-oxozeanol inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; bafilomycin A1 inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK3 protein]; Capsaicin results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; tricyclodecane-9-yl-xanthogenate inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased activity of MAPK3 protein]; Capsaicin results in increased activity of and results in increased phosphorylation of MAPK3 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; 7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Capsaicin inhibits the reaction [CCK protein results in increased phosphorylation of MAPK3 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein; Dizocilpine Maleate inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Genistein inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Lidocaine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Ro 31-8425 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]]; Ro 31-8425 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; Ro 31-8425 promotes the reaction [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]]; SR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; staurosporine aglycone inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; substance P (6-11), Tyr(6)-D-Phe(7)-D-His(9)- inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Xenon inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]		 CTD PMID:12196597 PMID:12478662 PMID:12941468 PMID:14530214 PMID:15385614 More... NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 increases phosphorylation ISO Capsaicin results in increased phosphorylation of MAPK7 protein CTD PMID:17237256 NCBI chr11:61,379,638...61,385,101
Ensembl chr11:61,379,638...61,385,232 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
increases activity		 ISO 7-oxozeanol inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; 7-oxozeanol promotes the reaction [MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]]; [Capsaicin results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein; Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK8 protein]; Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein; capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; DUSP1 mutant form promotes the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]; MAPK8 protein promotes the reaction [Capsaicin results in decreased degradation of TP53 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]
Capsaicin results in increased phosphorylation of MAPK8 protein		 CTD PMID:9580328 PMID:12478662 PMID:17292493 PMID:20619260 PMID:21462327 More... NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases activity
multiple interactions
increases phosphorylation		 ISO Capsaicin results in increased activity of MAPK9 protein
Capsaicin inhibits the reaction [EGF results in increased phosphorylation of MAPK9 protein]; Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK9 protein]
Capsaicin results in increased phosphorylation of MAPK9 protein		 CTD PMID:9580328 PMID:20619260 PMID:21462327 PMID:21745629 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248 		JBrowse link
G Mapt microtubule-associated protein tau increases expression ISO Capsaicin results in increased expression of MAPT mRNA CTD PMID:36044967 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression ISO Capsaicin results in increased expression of MARCKS mRNA CTD PMID:20349343 NCBI chr10:37,009,239...37,014,922
Ensembl chr10:37,009,371...37,014,916 		JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 increases expression ISO Capsaicin results in increased expression of MCL1 mRNA CTD PMID:19502594 PMID:36044967 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487 		JBrowse link
G Mdh1 malate dehydrogenase 1, NAD (soluble) multiple interactions ISO Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of MDH1 protein] CTD PMID:20359164 NCBI chr11:21,506,692...21,521,934
Ensembl chr11:21,506,692...21,522,367 		JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 increases expression
multiple interactions
decreases expression		 ISO Capsaicin results in increased expression of MDM2 mRNA
Capsaicin promotes the reaction [resveratrol results in decreased expression of MDM2 protein]; resveratrol promotes the reaction [Capsaicin results in decreased expression of MDM2 protein]; TP53 affects the reaction [Capsaicin results in decreased expression of MDM2 protein]		 CTD PMID:19502594 PMID:19846903 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) increases expression
multiple interactions		 ISO Capsaicin results in increased expression of MIF protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of MIF protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of MIF protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of MIF protein]		 CTD PMID:22150557 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions ISO Capsaicin inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MKI67 protein] CTD PMID:29155087 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Mmp12 matrix metallopeptidase 12 decreases expression EXP Capsaicin results in decreased expression of MMP12 mRNA; Capsaicin results in decreased expression of MMP12 protein CTD PMID:18441096 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499 		JBrowse link
G Mmp13 matrix metallopeptidase 13 decreases expression
increases expression
multiple interactions		 ISO Capsaicin results in decreased expression of MMP13 mRNA
Capsaicin results in increased expression of MMP13 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of MMP13 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of MMP13 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of MMP13 protein]		 CTD PMID:16278290 PMID:22150557 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331 		JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) multiple interactions ISO Capsaicin inhibits the reaction [EGF results in increased expression of MMP14] CTD PMID:21462327 NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821 		JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) multiple interactions
increases expression		 ISO capsazepine inhibits the reaction [Capsaicin results in increased expression of MMP1 protein]
Capsaicin results in increased expression of MMP1 mRNA; Capsaicin results in increased expression of MMP1 protein		 CTD PMID:17508023 PMID:21310942 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression		 ISO Capsaicin inhibits the reaction [EGF results in increased activity of MMP2 protein]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP2]
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of MMP2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of MMP2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of MMP2 protein]		 CTD PMID:21462327 PMID:22150557 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression		 ISO 4-aminobenzamide inhibits the reaction [Capsaicin results in increased activity of MMP9 protein]; Capsaicin inhibits the reaction [EGF results in increased activity of MMP9 protein]; Capsaicin inhibits the reaction [EGF results in increased expression of MMP9]; Capsaicin results in increased expression of and results in increased activity of MMP9 protein; TRPV1 inhibits the reaction [Capsaicin results in increased expression of and results in increased activity of MMP9 protein]
Capsaicin results in increased expression of MMP9 mRNA		 CTD PMID:21310942 PMID:21462327 PMID:22230393 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mobp myelin-associated oligodendrocytic basic protein increases expression ISO Capsaicin results in increased expression of MOBP mRNA CTD PMID:20349343 NCBI chr 9:119,978,740...120,010,554
Ensembl chr 9:119,978,773...120,010,550 		JBrowse link
G Mog myelin oligodendrocyte glycoprotein increases expression ISO Capsaicin results in increased expression of MOG mRNA CTD PMID:20349343 NCBI chr17:37,321,632...37,334,290
Ensembl chr17:37,321,635...37,334,290 		JBrowse link
G Mpo myeloperoxidase affects activity
multiple interactions
decreases expression		 ISO Capsaicin affects the activity of MPO protein
Capsaicin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Capsaicin inhibits the reaction [Diquat results in increased activity of MPO protein]; Capsaicin inhibits the reaction [Indomethacin results in increased activity of MPO protein]; Capsaicin inhibits the reaction [Iodoacetamide results in increased activity of MPO protein]; Capsaicin promotes the reaction [Ethanol results in increased activity of MPO protein]; Indomethacin inhibits the reaction [Capsaicin affects the activity of MPO protein]
Capsaicin results in decreased expression of MPO protein		 CTD PMID:10671773 PMID:12024109 PMID:12893632 PMID:15046732 PMID:15573930 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Mrpl3 mitochondrial ribosomal protein L3 decreases expression ISO Capsaicin results in decreased expression of MRPL3 mRNA CTD PMID:16278290 NCBI chr 9:104,930,394...104,954,665
Ensembl chr 9:104,930,438...104,957,087 		JBrowse link
G Msmo1 methylsterol monoxygenase 1 increases expression ISO Capsaicin results in increased expression of MSMO1 mRNA CTD PMID:18533110 NCBI chr 8:65,171,157...65,186,822
Ensembl chr 8:65,171,173...65,186,826 		JBrowse link
G mt-Nd1 NADH dehydrogenase 1, mitochondrial increases response to substance
multiple interactions		 ISO ND1 gene mutant form results in increased susceptibility to Capsaicin
[ND1 gene mutant form results in increased susceptibility to Capsaicin] which results in increased activity of CASP3 protein		 CTD PMID:29991444 NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
increases phosphorylation
decreases phosphorylation		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of MTOR protein]; acadesine promotes the reaction [Capsaicin results in decreased phosphorylation of MTOR protein]; dorsomorphin inhibits the reaction [Capsaicin results in decreased phosphorylation of MTOR protein]; Wortmannin inhibits the reaction [Capsaicin results in increased phosphorylation of MTOR protein] CTD PMID:19139269 PMID:22226932 PMID:36044967 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140 		JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric increases secretion
multiple interactions		 ISO Capsaicin results in increased secretion of MUC5AC protein
Capsaicin promotes the reaction [Citric Acid results in increased secretion of MUC5AC protein]		 CTD PMID:22566028 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968 		JBrowse link
G Muc5b mucin 5, subtype B, tracheobronchial increases secretion ISO Capsaicin results in increased secretion of MUC5B protein CTD PMID:21981454 NCBI chr 7:141,392,796...141,426,826
Ensembl chr 7:141,392,807...141,426,821 		JBrowse link
G Musk muscle, skeletal, receptor tyrosine kinase multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of MUSK protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of MUSK protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of MUSK protein] CTD PMID:22150557 NCBI chr 4:58,285,742...58,377,848
Ensembl chr 4:58,285,962...58,374,303 		JBrowse link
G Myc myelocytomatosis oncogene increases expression ISO Capsaicin results in increased expression of MYC mRNA CTD PMID:9461043 PMID:19502594 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Myl1 myosin, light polypeptide 1 multiple interactions ISO Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of MYL1 protein] CTD PMID:20359164 NCBI chr 1:66,963,454...66,987,091
Ensembl chr 1:66,963,454...66,984,563 		JBrowse link
G Myl4 myosin, light polypeptide 4 decreases expression ISO Capsaicin results in decreased expression of MYL4 mRNA CTD PMID:33512557 NCBI chr11:104,427,604...104,478,041
Ensembl chr11:104,441,489...104,486,579 		JBrowse link
G Ncr1 natural cytotoxicity triggering receptor 1 increases expression ISO Capsaicin results in increased expression of NCR1 mRNA CTD PMID:16278290 NCBI chr 7:4,340,714...4,348,183
Ensembl chr 7:4,340,723...4,348,163 		JBrowse link
G Ndufb4 NADH:ubiquinone oxidoreductase subunit B4 decreases expression ISO Capsaicin results in decreased expression of NDUFB4 mRNA CTD PMID:16278290 NCBI chr16:37,467,962...37,474,779
Ensembl chr16:37,467,532...37,474,815 		JBrowse link
G Nectin1 nectin cell adhesion molecule 1 increases expression ISO Capsaicin results in increased expression of NECTIN1 mRNA CTD PMID:16278290 NCBI chr 9:43,655,251...43,718,758
Ensembl chr 9:43,655,281...43,743,955 		JBrowse link
G Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 increases expression ISO Capsaicin results in increased expression of NEK2 mRNA CTD PMID:33512557 NCBI chr 1:191,553,622...191,565,161
Ensembl chr 1:191,553,556...191,565,162 		JBrowse link
G Nfatc4 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 increases localization ISO Capsaicin results in increased localization of NFATC4 protein CTD PMID:16849427 NCBI chr14:56,062,252...56,071,400
Ensembl chr14:56,060,601...56,071,400 		JBrowse link
G Nfe2 nuclear factor, erythroid derived 2 increases expression EXP Capsaicin results in increased expression of NFE2 mRNA CTD PMID:17603282 NCBI chr15:103,156,640...103,166,809
Ensembl chr15:103,156,639...103,166,830 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
increases localization		 ISO Acetylcysteine inhibits the reaction [Capsaicin results in increased localization of NFE2L2 protein] CTD PMID:17979524 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 affects expression
multiple interactions		 ISO Capsaicin affects the expression of NFKB1 mRNA
[NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]] which results in increased expression of DUSP1 protein; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK1 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased secretion of CXCL8 protein]; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased secretion of IL6 protein]		 CTD PMID:19502594 PMID:22171160 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions
decreases degradation
increases phosphorylation
increases localization		 ISO 7-oxozeanol promotes the reaction [MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]]; Capsaicin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; MAPK8 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of NFKBIA protein]
Capsaicin results in decreased degradation of NFKBIA protein
Capsaicin results in increased localization of NFKBIA protein		 CTD PMID:12214859 PMID:16540674 PMID:22171160 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Ngf nerve growth factor multiple interactions
decreases expression
increases expression
increases response to substance		 ISO
EXP		 NTRK1 promotes the reaction [NGF protein results in increased susceptibility to Capsaicin]; NTRK1 protein mutant form affects the reaction [NGF protein results in increased susceptibility to Capsaicin]
bisindolylmaleimide I inhibits the reaction [NGF results in increased susceptibility to Capsaicin]; Capsaicin inhibits the reaction [CCK protein alternative form results in decreased expression of NGF mRNA]; Capsaicin promotes the reaction [CCK protein alternative form results in increased expression of NGF protein]; KN 62 inhibits the reaction [NGF results in increased susceptibility to Capsaicin]; PIK3R1 gene mutant form inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; Staurosporine inhibits the reaction [NGF results in increased susceptibility to Capsaicin]; wortmannin inhibits the reaction [NGF results in increased susceptibility to Capsaicin]
Capsaicin results in decreased expression of NGF mRNA
Capsaicin results in increased expression of NGF protein
NGF protein results in increased susceptibility to Capsaicin; NGF results in increased susceptibility to Capsaicin
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [U 0126 inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; [Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein; [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NGF protein]; bisindolylmaleimide I inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; epothilone B affects the reaction [[Capsaicin co-treated with NGF protein] results in increased secretion of CALCA protein]; Ketotifen inhibits the reaction [Capsaicin results in increased expression of NGF protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of NGF protein]; NGF protein promotes the reaction [Capsaicin results in increased expression of CALCA protein]; NGF protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Promethazine inhibits the reaction [Capsaicin results in increased expression of NGF protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of NGF protein]; spantide II inhibits the reaction [Capsaicin results in increased expression of NGF protein]; staurosporine aglycone inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of NGF protein]; U 0126 inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]; U 0126 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin]]
Capsaicin results in decreased expression of NGF protein		 CTD PMID:9259450 PMID:10683199 PMID:11166474 PMID:12815188 PMID:15265675 More... NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329 		JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) increases expression
decreases expression
multiple interactions		 ISO Capsaicin results in increased expression of NGFR protein
Capsaicin results in decreased expression of NGFR mRNA
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NGFR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of NGFR protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of NGFR protein]		 CTD PMID:8971780 PMID:22150557 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression ISO Capsaicin results in increased expression of NME2 mRNA CTD PMID:21310942 NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal increases expression
multiple interactions		 ISO Capsaicin results in increased expression of NOS1 protein
TP53 affects the reaction [Capsaicin results in increased expression of NOS1 protein]
Capsaicin results in increased expression of NOS1 mRNA; Capsaicin results in increased expression of NOS1 protein		 CTD PMID:7477891 PMID:10880996 PMID:11576744 PMID:19846903 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
increases expression		 ISO
EXP		 Capsaicin promotes the reaction [resveratrol results in increased expression of NOS2 protein]; resveratrol promotes the reaction [Capsaicin results in increased expression of NOS2 protein]; TP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS2 protein]]; TP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS2 protein]]
Capsaicin inhibits the reaction [[IFNG protein results in increased abundance of Nitric Oxide] which results in increased expression of NOS2 protein]; Capsaicin inhibits the reaction [[Lipopolysaccharides results in increased abundance of Nitric Oxide] which results in increased expression of NOS2 protein]; Capsaicin inhibits the reaction [IFNG results in increased expression of NOS2 protein]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
Capsaicin results in increased expression of NOS2; Capsaicin results in increased expression of NOS2 mRNA; Capsaicin results in increased expression of NOS2 protein
Capsaicin inhibits the reaction [Indomethacin results in increased activity of NOS2 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 protein]		 CTD PMID:10671773 PMID:11576744 PMID:14530214 PMID:15681035 PMID:19846903 More... NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions
increases expression
decreases expression		 ISO Capsaicin promotes the reaction [resveratrol results in increased expression of NOS3 protein]; resveratrol promotes the reaction [Capsaicin results in increased expression of NOS3 protein]; TP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS3 protein]]; TP53 affects the reaction [Capsaicin results in increased expression of NOS3 protein]; TP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS3 protein]]
Capsaicin results in decreased expression of NOS3 mRNA		 CTD PMID:16278290 PMID:18037908 PMID:19846903 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Nox3 NADPH oxidase 3 multiple interactions
increases expression		 ISO
EXP		 NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 protein]
Capsaicin results in increased expression of NOX3 mRNA; Capsaicin results in increased expression of NOX3 protein
NOX3 mutant form inhibits the reaction [Capsaicin results in increased abundance of Reactive Oxygen Species]		 CTD PMID:20712533 NCBI chr17:3,685,515...3,746,536
Ensembl chr17:3,685,515...3,746,536 		JBrowse link
G Nox4 NADPH oxidase 4 affects expression ISO Capsaicin affects the expression of NOX4 mRNA; Capsaicin affects the expression of NOX4 protein CTD PMID:34939720 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 increases expression ISO Capsaicin results in increased expression of NPC1 mRNA CTD PMID:18533110 PMID:36044967 NCBI chr18:12,322,751...12,369,851
Ensembl chr18:12,322,749...12,369,457 		JBrowse link
G Npy neuropeptide Y multiple interactions ISO Capsaicin inhibits the reaction [NPY protein affects the susceptibility to Potassium] CTD PMID:18055875 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 multiple interactions
increases response to substance		 ISO neuropeptide Y, Leu(31)-Pro(34)- inhibits the reaction [NPY1R protein results in increased susceptibility to Capsaicin] CTD PMID:16714086 NCBI chr 8:67,149,595...67,159,452
Ensembl chr 8:67,149,844...67,159,444 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions
decreases expression
increases expression		 EXP
ISO		 Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased activity of NQO1 protein]
Capsaicin results in decreased expression of NQO1 protein
Capsaicin results in increased expression of NQO1
Capsaicin results in increased expression of NQO1 mRNA		 CTD PMID:10880996 PMID:17979524 PMID:19449198 PMID:33512557 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide quinone reductase 2 multiple interactions ISO Capsaicin inhibits the reaction [Dietary Fats results in increased expression of NQO2 protein] CTD PMID:20359164 NCBI chr13:34,148,642...34,172,448
Ensembl chr13:34,148,670...34,172,426 		JBrowse link
G Nrp1 neuropilin 1 multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of NRP1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of NRP1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of NRP1 protein] CTD PMID:22150557 NCBI chr 8:129,085,553...129,231,957
Ensembl chr 8:129,085,085...129,229,844 		JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 multiple interactions
decreases expression		 ISO NTRK1 promotes the reaction [NGF protein results in increased susceptibility to Capsaicin]; NTRK1 protein mutant form affects the reaction [NGF protein results in increased susceptibility to Capsaicin]
Capsaicin results in decreased expression of NTRK1 mRNA		 CTD PMID:8971780 PMID:9259450 PMID:17324588 NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469 		JBrowse link
G Nupr1 nuclear protein transcription regulator 1 increases expression ISO Capsaicin results in increased expression of NUPR1 mRNA CTD PMID:36044967 NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033 		JBrowse link
G Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) multiple interactions EXP Capsaicin inhibits the reaction [Benzo(a)pyrene results in decreased expression of OGDH] CTD PMID:18023135 NCBI chr11:6,241,597...6,309,094
Ensembl chr11:6,241,633...6,306,642 		JBrowse link
G Olig1 oligodendrocyte transcription factor 1 increases expression ISO Capsaicin results in increased expression of OLIG1 mRNA CTD PMID:20349343 NCBI chr16:91,066,657...91,068,827
Ensembl chr16:91,066,660...91,068,821 		JBrowse link
G Oprl1 opioid receptor-like 1 multiple interactions ISO OPRL1 protein promotes the reaction [nociceptin (1-13) amide inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]] CTD PMID:17640294 NCBI chr 2:181,356,585...181,362,778
Ensembl chr 2:181,356,809...181,362,778 		JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO Capsaicin inhibits the reaction [carfentanil binds to OPRM1 protein] CTD PMID:12406535 NCBI chr10:6,708,593...6,988,209
Ensembl chr10:6,708,506...6,988,198 		JBrowse link
G Optn optineurin increases expression ISO Capsaicin results in increased expression of OPTN mRNA CTD PMID:36044967 NCBI chr 2:5,023,902...5,069,210
Ensembl chr 2:5,025,453...5,068,862 		JBrowse link
G Or8d1b olfactory receptor family 8 subfamily D member 1B increases expression ISO Capsaicin results in increased expression of OLR1271 mRNA CTD PMID:16278290 NCBI chr 9:38,886,974...38,887,900
Ensembl chr 9:38,883,609...38,891,157 		JBrowse link
G P2ry2 purinergic receptor P2Y, G-protein coupled 2 affects response to substance
multiple interactions		 EXP P2RY2 protein affects the susceptibility to Capsaicin
KNG1 protein alternative form affects the reaction [P2RY2 protein affects the susceptibility to Capsaicin]		 CTD PMID:18343036 NCBI chr 7:100,645,775...100,661,260
Ensembl chr 7:100,645,775...100,662,073 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage
multiple interactions
increases ADP-ribosylation
increases expression		 EXP
ISO		 Capsaicin results in increased cleavage of PARP1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; 3-aminobenzamide inhibits the reaction [Capsaicin results in increased ADP-ribosylation of PARP1 protein modified form]; 3-aminobenzamide promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; 3-aminobenzamide promotes the reaction [Capsaicin results in increased expression of PARP1 protein]; Caffeine promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased cleavage of PARP1 protein]; Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein; pifithrin promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]		 CTD PMID:17295509 PMID:17505005 PMID:19855437 PMID:22200406 PMID:22226932 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pclaf PCNA clamp associated factor increases expression ISO Capsaicin results in increased expression of PCLAF mRNA CTD PMID:20349343 NCBI chr 9:65,797,605...65,810,833
Ensembl chr 9:65,797,519...65,810,548 		JBrowse link
G Pcolce procollagen C-endopeptidase enhancer protein increases expression ISO Capsaicin results in increased expression of PCOLCE mRNA CTD PMID:16278290 NCBI chr 5:137,603,369...137,609,666
Ensembl chr 5:137,603,365...137,612,046 		JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 decreases expression ISO Capsaicin results in decreased expression of PCSK5 mRNA CTD PMID:16278290 NCBI chr19:17,409,678...17,815,076
Ensembl chr19:17,409,683...17,814,996 		JBrowse link
G Pctp phosphatidylcholine transfer protein decreases expression ISO Capsaicin results in decreased expression of PCTP mRNA CTD PMID:18533110 NCBI chr11:89,873,370...89,893,720
Ensembl chr11:89,873,491...89,893,720 		JBrowse link
G Pde2a phosphodiesterase 2A, cGMP-stimulated decreases expression ISO Capsaicin results in decreased expression of PDE2A mRNA CTD PMID:20349343 NCBI chr 7:101,070,905...101,162,026
Ensembl chr 7:101,060,093...101,162,026
Ensembl chr 7:101,060,093...101,162,026 		JBrowse link
G Pdgfa platelet derived growth factor, alpha increases expression
multiple interactions		 ISO Capsaicin results in increased expression of PDGFA protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PDGFA protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PDGFA protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of PDGFA protein]		 CTD PMID:22150557 NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 decreases expression ISO Capsaicin results in decreased expression of PDX1 mRNA CTD PMID:16278290 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658 		JBrowse link
G Pdyn prodynorphin increases expression
multiple interactions		 ISO Capsaicin results in increased expression of PDYN mRNA; Capsaicin results in increased expression of PDYN protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased expression of PDYN protein]		 CTD PMID:15385614 NCBI chr 2:129,528,469...129,541,858
Ensembl chr 2:129,528,485...129,541,764 		JBrowse link
G Pdzd2 PDZ domain containing 2 increases expression ISO Capsaicin results in increased expression of PDZD2 mRNA CTD PMID:16278290 NCBI chr15:12,359,797...12,740,052
Ensembl chr15:12,359,797...12,740,010 		JBrowse link
G Per2 period circadian clock 2 increases expression ISO Capsaicin results in increased expression of PER2 mRNA CTD PMID:24746025 NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046 		JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression
decreases expression		 ISO Capsaicin results in increased expression of PGM1 mRNA; Capsaicin results in increased expression of PGM1 protein
Capsaicin results in decreased expression of PGM1 mRNA		 CTD PMID:19891501 PMID:20349343 NCBI chr 4:99,786,648...99,844,491
Ensembl chr 4:99,786,611...99,844,491 		JBrowse link
G Phb2 prohibitin 2 multiple interactions ISO Capsaicin binds to and results in increased localization of PHB2 protein CTD PMID:19116139 NCBI chr 6:124,689,252...124,693,908
Ensembl chr 6:124,689,299...124,693,913 		JBrowse link
G Phox2a paired-like homeobox 2a increases expression ISO Capsaicin results in increased expression of PHOX2A mRNA CTD PMID:16278290 NCBI chr 7:101,467,520...101,471,933
Ensembl chr 7:101,467,520...101,471,933 		JBrowse link
G Phykpl 5-phosphohydroxy-L-lysine phospholyase increases expression ISO Capsaicin results in increased expression of PHYKPL mRNA CTD PMID:20349343 NCBI chr11:51,474,751...51,494,091
Ensembl chr11:51,475,584...51,495,316 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions EXP PIK3R1 gene mutant form inhibits the reaction [NGF protein results in increased susceptibility to Capsaicin] CTD PMID:17324588 NCBI chr13:101,817,269...101,904,725
Ensembl chr13:101,817,071...101,904,725 		JBrowse link
G Pink1 PTEN induced putative kinase 1 increases expression ISO Capsaicin results in increased expression of PINK1 mRNA CTD PMID:36044967 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618 		JBrowse link
G Pla2g15 phospholipase A2, group XV decreases expression ISO Capsaicin results in decreased expression of PLA2G15 mRNA CTD PMID:20349343 NCBI chr 8:106,876,986...106,891,350
Ensembl chr 8:106,877,031...106,891,347 		JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) multiple interactions
increases phosphorylation		 ISO SB 203580 inhibits the reaction [Capsaicin results in increased phosphorylation of PLA2G4A protein] CTD PMID:19959817 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041 		JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO Capsaicin results in increased expression of PLAU mRNA CTD PMID:21310942 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression ISO Capsaicin results in increased expression of PLAUR mRNA CTD PMID:21310942 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
G Plcb3 phospholipase C, beta 3 decreases expression ISO Capsaicin results in decreased expression of PLCB3 mRNA CTD PMID:20349343 NCBI chr19:6,931,081...6,951,738
Ensembl chr19:6,929,693...6,953,838 		JBrowse link
G Plin2 perilipin 2 affects expression
multiple interactions		 ISO Capsaicin affects the expression of PLIN2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of PLIN2 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of PLIN2 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of PLIN2 protein]		 CTD PMID:22150557 NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297 		JBrowse link
G Plp1 proteolipid protein (myelin) 1 increases expression ISO Capsaicin results in increased expression of PLP1 mRNA CTD PMID:20349343 NCBI chr  X:135,720,897...135,739,331
Ensembl chr  X:135,723,420...135,740,482 		JBrowse link
G Pnisr PNN interacting serine/arginine-rich increases expression ISO Capsaicin results in increased expression of PNISR mRNA CTD PMID:20349343 NCBI chr 4:21,846,621...21,876,475
Ensembl chr 4:21,847,583...21,876,475 		JBrowse link
G Polb polymerase (DNA directed), beta decreases expression ISO Capsaicin results in decreased expression of POLB mRNA CTD PMID:16278290 NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451 		JBrowse link
G Polr2f polymerase (RNA) II (DNA directed) polypeptide F increases expression ISO Capsaicin results in increased expression of POLR2F mRNA CTD PMID:16278290 NCBI chr15:79,025,525...79,035,974
Ensembl chr15:79,025,209...79,035,974 		JBrowse link
G Pomc pro-opiomelanocortin-alpha multiple interactions
increases expression
increases secretion		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of POMC protein]; Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein]; Capsaicin inhibits the reaction [[Morphine co-treated with Naloxone] results in increased secretion of POMC protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; CP 96345 inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; Dizocilpine Maleate inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; Lidocaine inhibits the reaction [Capsaicin results in increased secretion of POMC protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of POMC protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of POMC protein] CTD PMID:2846107 PMID:8925284 PMID:22150557 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions EXP Capsaicin inhibits the reaction [Benzo(a)pyrene results in increased expression of POR protein] CTD PMID:19449198 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
increases expression		 ISO
EXP		 Capsaicin results in decreased expression of PPARA mRNA
Capsaicin results in increased expression of PPARA mRNA		 CTD PMID:18769453 PMID:19798065 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Ppard peroxisome proliferator activator receptor delta decreases expression ISO Capsaicin results in decreased expression of PPARD mRNA CTD PMID:18769453 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions
decreases expression
increases activity		 ISO
EXP		 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Capsaicin results in increased activity of PPARG protein]
Capsaicin results in decreased expression of PPARG mRNA
Capsaicin results in decreased expression of PPARG protein
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of PPARG mRNA]		 CTD PMID:15383218 PMID:17295509 PMID:18769453 PMID:20359164 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression
multiple interactions		 EXP
ISO		 Capsaicin results in increased expression of PPARGC1A mRNA
Capsaicin promotes the reaction [Dietary Fats results in increased expression of PPARGC1A mRNA]		 CTD PMID:19798065 PMID:20359164 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions ISO Capsaicin inhibits the reaction [Colforsin results in increased phosphorylation of PPP1R12A protein] CTD PMID:21474433 NCBI chr10:107,997,913...108,115,846
Ensembl chr10:107,998,054...108,120,336 		JBrowse link
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform multiple interactions ISO PPP3CA protein affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]] CTD PMID:17590514 NCBI chr 3:136,375,778...136,643,488
Ensembl chr 3:136,375,885...136,643,488 		JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit increases expression ISO Capsaicin results in increased expression of PPP5C mRNA CTD PMID:16278290 NCBI chr 7:16,738,575...16,761,812
Ensembl chr 7:16,738,565...16,761,849 		JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO Capsaicin inhibits the reaction [Dietary Fats results in increased expression of PRDX1 protein] CTD PMID:20359164 NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019 		JBrowse link
G Prdx6 peroxiredoxin 6 increases expression ISO Capsaicin results in increased expression of PRDX6 protein CTD PMID:18991268 NCBI chr 1:161,067,682...161,078,780
Ensembl chr 1:161,067,682...161,078,789 		JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit multiple interactions
increases expression
increases phosphorylation		 ISO [Genistein co-treated with Capsaicin] results in increased activity of PRKAA1 protein; acadesine promotes the reaction [Capsaicin results in increased expression of PRKAA1 protein]; dorsomorphin inhibits the reaction [Capsaicin results in increased expression of PRKAA1 protein]
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PRKAA1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PRKAA1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of PRKAA1 protein]
Capsaicin results in increased phosphorylation of PRKAA1 protein		 CTD PMID:19723084 PMID:22150557 PMID:36044967 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380 		JBrowse link
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit increases phosphorylation
multiple interactions		 ISO Capsaicin results in increased phosphorylation of PRKAA2 protein
acadesine promotes the reaction [Capsaicin results in increased expression of PRKAA2 protein]; dorsomorphin inhibits the reaction [Capsaicin results in increased expression of PRKAA2 protein]		 CTD PMID:36044967 NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087 		JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha increases phosphorylation EXP Capsaicin results in increased phosphorylation of PRKACA protein CTD PMID:21908651 NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072 		JBrowse link
G Prkca protein kinase C, alpha increases expression
multiple interactions		 ISO Capsaicin results in increased expression of PRKCA mRNA; Capsaicin results in increased expression of PRKCA protein
chelerythrine inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]; iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]
bisindolylmaleimide inhibits the reaction [Capsaicin results in increased expression of PRKCA protein]		 CTD PMID:18752301 PMID:21474332 NCBI chr11:107,824,213...108,237,360
Ensembl chr11:107,824,213...108,234,754 		JBrowse link
G Prkcd protein kinase C, delta increases expression
multiple interactions		 ISO Capsaicin results in increased expression of PRKCD protein
[NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]] which results in increased expression of DUSP1 protein; NFKB1 mutant form inhibits the reaction [Capsaicin results in increased expression of PRKCD protein]		 CTD PMID:22171160 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167 		JBrowse link
G Prkce protein kinase C, epsilon multiple interactions ISO PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] CTD PMID:16793902 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347 		JBrowse link
G Prkcz protein kinase C, zeta increases response to substance EXP PRKCZ protein alternative form results in increased susceptibility to Capsaicin CTD PMID:27899695 NCBI chr 4:155,344,579...155,445,856
Ensembl chr 4:155,344,586...155,445,818 		JBrowse link
G Prkd1 protein kinase D1 multiple interactions ISO PRKD1 promotes the reaction [Capsaicin results in increased uptake of Calcium]
PRKD1 mutant form inhibits the reaction [Capsaicin results in increased uptake of Calcium]		 CTD PMID:15471852 NCBI chr12:50,388,009...50,696,075
Ensembl chr12:50,388,014...50,695,881 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide multiple interactions
increases phosphorylation		 ISO 3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of PRKDC protein]; ATG5 mutant form inhibits the reaction [Capsaicin results in increased phosphorylation of PRKDC protein]; Capsaicin results in increased phosphorylation of and results in increased activity of PRKDC protein; pifithrin inhibits the reaction [Capsaicin results in increased phosphorylation of PRKDC protein] CTD PMID:22226932 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Prlr prolactin receptor increases expression
multiple interactions		 ISO Capsaicin results in increased expression of PRLR protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PRLR protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PRLR protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of PRLR protein]		 CTD PMID:22150557 NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266 		JBrowse link
G Prok1 prokineticin 1 multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of PROK1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of PROK1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of PROK1 protein] CTD PMID:22150557 NCBI chr 3:107,139,232...107,147,023
Ensembl chr 3:107,140,113...107,147,023 		JBrowse link
G Prok2 prokineticin 2 increases response to substance EXP PROK2 protein results in increased susceptibility to Capsaicin CTD PMID:17107623 NCBI chr 6:99,687,833...99,703,368
Ensembl chr 6:99,688,260...99,703,353 		JBrowse link
G Prokr1 prokineticin receptor 1 multiple interactions
increases response to substance		 EXP PROKR1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]
PROKR1 protein results in increased susceptibility to Capsaicin		 CTD PMID:16793879 NCBI chr 6:87,555,568...87,567,741
Ensembl chr 6:87,555,573...87,567,725 		JBrowse link
G Prokr2 prokineticin receptor 2 decreases expression ISO Capsaicin results in decreased expression of PROKR2 mRNA CTD PMID:16278290 NCBI chr 2:132,211,625...132,227,413
Ensembl chr 2:132,179,653...132,227,367 		JBrowse link
G Ptgir prostaglandin I receptor (IP) increases response to substance EXP PTGIR results in increased susceptibility to Capsaicin CTD PMID:15985616 NCBI chr 7:16,640,442...16,644,828
Ensembl chr 7:16,640,415...16,644,830 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
increases expression		 ISO
EXP		 Capsaicin promotes the reaction [Genistein results in decreased expression of PTGS2 protein]
Capsaicin results in decreased expression of PTGS2 protein
Capsaicin results in decreased expression of PTGS2 mRNA
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein; Capsaicin inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; EGFR gene mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; RTKI cpd inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; SRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]
Capsaicin results in increased expression of PTGS2 mRNA; Capsaicin results in increased expression of PTGS2 protein
[Genistein co-treated with Capsaicin] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Botulinum Toxins, Type A inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]		 CTD PMID:11125845 PMID:14530214 PMID:17141941 PMID:17719033 PMID:19723084 More... NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 multiple interactions ISO Capsaicin inhibits the reaction [EGF results in increased phosphorylation of PTK2 protein] CTD PMID:21462327 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) increases expression ISO Capsaicin results in increased expression of PTPN22 mRNA CTD PMID:36044967 NCBI chr 3:103,763,891...103,819,568
Ensembl chr 3:103,767,111...103,819,563 		JBrowse link
G Rab39b RAB39B, member RAS oncogene family increases expression ISO Capsaicin results in increased expression of RAB39B mRNA CTD PMID:36044967 NCBI chr  X:74,615,651...74,621,837
Ensembl chr  X:74,615,652...74,621,837 		JBrowse link
G Ranbp3l RAN binding protein 3-like increases expression ISO Capsaicin results in increased expression of RANBP3L mRNA CTD PMID:20349343 NCBI chr15:8,997,209...9,071,355
Ensembl chr15:8,997,433...9,067,417 		JBrowse link
G Rarres2 retinoic acid receptor responder (tazarotene induced) 2 multiple interactions EXP RARRES2 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] CTD PMID:20383154 NCBI chr 6:48,546,630...48,549,778
Ensembl chr 6:48,546,630...48,549,723 		JBrowse link
G Rbm5 RNA binding motif protein 5 increases expression ISO Capsaicin results in increased expression of RBM5 mRNA CTD PMID:20349343 NCBI chr 9:107,617,694...107,648,228
Ensembl chr 9:107,617,570...107,648,195 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) decreases activity
decreases localization		 EXP
ISO		 Capsaicin results in decreased activity of RELA protein
Capsaicin results in decreased localization of RELA protein		 CTD PMID:12214859 PMID:16540674 PMID:17719033 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Retn resistin increases expression
multiple interactions		 ISO Capsaicin results in increased expression of RETN protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of RETN protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of RETN protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of RETN protein]		 CTD PMID:22150557 NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110 		JBrowse link
G Retnlb resistin like beta multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of RETNLB protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of RETNLB protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of RETNLB protein] CTD PMID:22150557 NCBI chr16:48,637,219...48,639,255
Ensembl chr16:48,637,219...48,639,255 		JBrowse link
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 increases expression ISO Capsaicin results in increased expression of RIPK2 mRNA CTD PMID:19502594 NCBI chr 4:16,122,740...16,163,674
Ensembl chr 4:16,122,733...16,163,647 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase polypeptide 3 increases expression ISO Capsaicin results in increased expression of RPS6KA3 protein CTD PMID:18991268 NCBI chr  X:158,038,652...158,151,240
Ensembl chr  X:157,993,303...158,151,240 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 decreases phosphorylation
increases phosphorylation		 ISO Capsaicin results in decreased phosphorylation of RPS6KB1 protein
Capsaicin results in increased phosphorylation of RPS6KB1 mRNA		 CTD PMID:22226932 PMID:36044967 NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631 		JBrowse link
G Rragc Ras-related GTP binding C increases expression ISO Capsaicin results in increased expression of RRAGC mRNA CTD PMID:36044967 NCBI chr 4:123,811,226...123,830,790
Ensembl chr 4:123,811,239...123,830,790 		JBrowse link
G Rragd Ras-related GTP binding D increases expression ISO Capsaicin results in increased expression of RRAGD mRNA CTD PMID:36044967 NCBI chr 4:32,982,998...33,022,180
Ensembl chr 4:32,983,037...33,022,180 		JBrowse link
G Rxra retinoid X receptor alpha decreases expression ISO Capsaicin results in decreased expression of RXRA mRNA CTD PMID:18769453 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969 		JBrowse link
G Rxrb retinoid X receptor beta decreases expression ISO Capsaicin results in decreased expression of RXRB mRNA CTD PMID:18769453 NCBI chr17:34,250,786...34,257,377
Ensembl chr17:34,250,786...34,257,373 		JBrowse link
G S100a4 S100 calcium binding protein A4 increases expression ISO Capsaicin results in increased expression of S100A4 mRNA CTD PMID:21310942 NCBI chr 3:90,511,077...90,513,349
Ensembl chr 3:90,511,078...90,513,352 		JBrowse link
G S100b S100 protein, beta polypeptide, neural increases expression ISO Capsaicin results in increased expression of S100B protein CTD PMID:17635592 NCBI chr10:76,089,670...76,097,153
Ensembl chr10:76,089,687...76,096,993 		JBrowse link
G S100g S100 calcium binding protein G increases expression ISO Capsaicin results in increased expression of S100G mRNA CTD PMID:16278290 NCBI chr  X:161,744,988...161,747,595
Ensembl chr  X:161,744,988...161,747,595 		JBrowse link
G Scn10a sodium channel, voltage-gated, type X, alpha multiple interactions
increases response to substance		 EXP SCN10A protein affects the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]
SCN10A results in increased susceptibility to Capsaicin		 CTD PMID:12351708 PMID:18845912 NCBI chr 9:119,437,522...119,548,388
Ensembl chr 9:119,437,522...119,548,388 		JBrowse link
G Scp2 sterol carrier protein 2, liver decreases expression ISO Capsaicin results in decreased expression of SCP2 mRNA CTD PMID:18533110 NCBI chr 4:107,901,027...108,002,168
Ensembl chr 4:107,901,036...108,002,195 		JBrowse link
G Sele selectin, endothelial cell increases expression
multiple interactions		 ISO Capsaicin results in increased expression of SELE protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SELE protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of SELE protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of SELE protein]		 CTD PMID:22150557 NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246 		JBrowse link
G Sell selectin, lymphocyte increases expression
multiple interactions		 ISO Capsaicin results in increased expression of SELL protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SELL protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of SELL protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of SELL protein]		 CTD PMID:22150557 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750 		JBrowse link
G Senp5 SUMO/sentrin specific peptidase 5 decreases expression ISO Capsaicin results in decreased expression of SENP5 mRNA CTD PMID:20349343 NCBI chr16:31,778,488...31,829,388
Ensembl chr16:31,778,490...31,822,105 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 decreases expression ISO Capsaicin results in decreased expression of SERPINE1 mRNA CTD PMID:21310942 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Sesn1 sestrin 1 increases expression ISO Capsaicin results in increased expression of SESN1 mRNA CTD PMID:36044967 NCBI chr10:41,686,570...41,784,432
Ensembl chr10:41,685,931...41,784,420 		JBrowse link
G Sesn3 sestrin 3 increases expression ISO Capsaicin results in increased expression of SESN3 mRNA CTD PMID:36044967 NCBI chr 9:14,187,597...14,237,430
Ensembl chr 9:14,186,363...14,244,397 		JBrowse link
G Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) increases expression ISO Capsaicin results in increased expression of SFPQ mRNA CTD PMID:20349343 NCBI chr 4:126,914,504...126,944,894
Ensembl chr 4:126,915,117...126,930,806 		JBrowse link
G Sh3bp5 SH3-domain binding protein 5 (BTK-associated) decreases expression ISO Capsaicin results in decreased expression of SH3BP5 mRNA CTD PMID:16278290 NCBI chr14:31,094,571...31,158,056
Ensembl chr14:31,081,837...31,158,035 		JBrowse link
G Sh3kbp1 SH3-domain kinase binding protein 1 increases expression ISO Capsaicin results in increased expression of SH3KBP1 mRNA CTD PMID:16278290 NCBI chr  X:158,409,888...158,758,916
Ensembl chr  X:158,410,268...158,761,065 		JBrowse link
G Sirt1 sirtuin 1 affects expression ISO Capsaicin affects the expression of SIRT1 mRNA; Capsaicin affects the expression of SIRT1 protein CTD PMID:34939720 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Slc12a1 solute carrier family 12, member 1 multiple interactions
increases expression		 ISO [Capsaicin co-treated with Sodium Chloride, Dietary] results in increased expression of SLC12A1 mRNA
Capsaicin results in increased expression of SLC12A1 mRNA		 CTD PMID:17414671 NCBI chr 2:124,994,430...125,071,922
Ensembl chr 2:124,994,425...125,071,922 		JBrowse link
G Slc12a2 solute carrier family 12, member 2 affects response to substance EXP SLC12A2 affects the susceptibility to Capsaicin CTD PMID:15135928 NCBI chr18:58,011,505...58,079,893
Ensembl chr18:58,011,750...58,079,893 		JBrowse link
G Slc16a10 solute carrier family 16 (monocarboxylic acid transporters), member 10 decreases expression ISO Capsaicin results in decreased expression of SLC16A10 mRNA CTD PMID:16278290 NCBI chr10:39,909,528...40,018,262
Ensembl chr10:39,909,528...40,018,254 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Capsaicin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375 		JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 increases expression EXP Capsaicin results in increased expression of SLC2A4 mRNA CTD PMID:19798065 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014 		JBrowse link
G Slc37a1 solute carrier family 37 (glycerol-3-phosphate transporter), member 1 decreases expression ISO Capsaicin results in decreased expression of SLC37A1 mRNA CTD PMID:20349343 NCBI chr17:31,495,722...31,569,683
Ensembl chr17:31,505,766...31,569,713 		JBrowse link
G Slit1 slit guidance ligand 1 increases expression ISO Capsaicin results in increased expression of SLIT1 mRNA CTD PMID:16278290 NCBI chr19:41,586,263...41,735,714
Ensembl chr19:41,588,696...41,732,104 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression
multiple interactions
decreases response to substance		 EXP Capsaicin results in increased expression of SOD2 protein modified form
phenyl-N-tert-butylnitrone inhibits the reaction [Capsaicin results in decreased activity of SOD2 protein]; phenyl-N-tert-butylnitrone inhibits the reaction [Capsaicin results in increased expression of SOD2 protein modified form]; tempol inhibits the reaction [Capsaicin results in decreased activity of SOD2 protein]; tempol inhibits the reaction [Capsaicin results in increased expression of SOD2 protein modified form]
SOD2 results in decreased susceptibility to Capsaicin		 CTD PMID:19129394 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Sostdc1 sclerostin domain containing 1 increases expression ISO Capsaicin results in increased expression of SOSTDC1 mRNA CTD PMID:20349343 NCBI chr12:36,364,168...36,368,451
Ensembl chr12:36,364,138...36,368,451 		JBrowse link
G Sp1 trans-acting transcription factor 1 multiple interactions
increases localization		 ISO Capsaicin promotes the reaction [SP1 protein binds to TNFSF10 promoter]
Capsaicin results in increased localization of SP1 protein		 CTD PMID:22200406 NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839 		JBrowse link
G Spi1 Spi-1 proto-oncogene increases expression EXP Capsaicin results in increased expression of SPI1 mRNA CTD PMID:17603282 NCBI chr 2:90,912,750...90,946,104
Ensembl chr 2:90,912,735...90,946,101 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of SPP1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of SPP1 protein]; Sumatriptan promotes the reaction [Capsaicin results in increased expression of SPP1 protein] CTD PMID:22150557 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Src Rous sarcoma oncogene multiple interactions
increases activity		 ISO
EXP		 Capsaicin results in decreased phosphorylation of and results in decreased activity of SRC protein
SRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]
Capsaicin results in increased activity of SRC protein
AG 1879 inhibits the reaction [Capsaicin results in increased activity of SRC protein]		 CTD PMID:17505005 PMID:20660715 PMID:21340460 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO Capsaicin results in increased expression of SREBF1 mRNA CTD PMID:36044967 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G Sst somatostatin multiple interactions
increases expression
decreases expression
increases secretion		 ISO
EXP		 AMN protein inhibits the reaction [Capsaicin results in increased expression of SST protein]
Capsaicin results in decreased expression of SST mRNA
Capsaicin results in increased secretion of SST protein		 CTD PMID:8093704 PMID:8093880 PMID:9932722 PMID:16938409 PMID:19296048 More... NCBI chr16:23,708,327...23,710,041
Ensembl chr16:23,708,323...23,709,708 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression
multiple interactions
increases response to substance		 ISO
EXP		 Capsaicin results in increased expression of STAT1 mRNA; Capsaicin results in increased expression of STAT1 protein
Capsaicin results in increased phosphorylation of and results in increased activity of STAT1 protein; CYBB mutant form inhibits the reaction [Capsaicin results in increased expression of STAT1 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOS2 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of NOX3 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of PTGS2 protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein]
STAT1 results in increased susceptibility to Capsaicin
Capsaicin inhibits the reaction [IFNG results in increased activity of STAT1 protein]; Capsaicin results in increased phosphorylation of and results in increased activity of STAT1 protein		 CTD PMID:14530214 PMID:20712533 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
affects localization
increases phosphorylation		 ISO Bortezomib promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]; Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]; Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein; pervanadate inhibits the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]; Thalidomide promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]
Capsaicin affects the localization of STAT3 protein
Capsaicin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; SR140333B inhibits the reaction [Capsaicin results in increased phosphorylation of STAT3 protein]		 CTD PMID:16788306 PMID:17505005 PMID:19285962 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Steap3 STEAP family member 3 multiple interactions ISO Capsaicin inhibits the reaction [Dietary Fats results in increased expression of STEAP3 protein] CTD PMID:20359164 NCBI chr 1:120,154,137...120,198,810
Ensembl chr 1:120,118,487...120,200,435 		JBrowse link
G Suv39h1 suppressor of variegation 3-9 1 decreases expression ISO Capsaicin results in decreased expression of SUV39H1 mRNA CTD PMID:16278290 NCBI chr  X:7,927,401...7,940,994
Ensembl chr  X:7,927,410...7,940,999 		JBrowse link
G Syn2 synapsin II increases response to substance EXP SYN2 results in increased susceptibility to Capsaicin CTD PMID:18701217 NCBI chr 6:115,111,863...115,259,587
Ensembl chr 6:115,111,863...115,258,967 		JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) affects response to substance EXP SYNGAP1 affects the susceptibility to Capsaicin CTD PMID:21525372 NCBI chr17:27,160,186...27,191,408
Ensembl chr17:27,160,227...27,191,408 		JBrowse link
G Syt7 synaptotagmin VII increases expression ISO Capsaicin results in increased expression of SYT7 mRNA CTD PMID:16278290 NCBI chr19:10,366,142...10,430,545
Ensembl chr19:10,366,454...10,430,544 		JBrowse link
G Tac1 tachykinin 1 affects expression
decreases expression
increases expression
increases secretion
multiple interactions
decreases secretion
decreases activity		 EXP
ISO		 Capsaicin affects the expression of TAC1 protein
Capsaicin results in decreased expression of TAC1 mRNA
Capsaicin results in increased expression of TAC1 mRNA; Capsaicin results in increased expression of TAC1 protein
Capsaicin results in increased secretion of TAC1 protein; Capsaicin results in increased secretion of TAC1 protein alternative form; Capsaicin results in increased secretion of TAC1 protein modified form
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; 2-aminoethyl diphenylborinate inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; AMN protein inhibits the reaction [Capsaicin results in increased expression of TAC1 protein]; bisindolylmaleimide I inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Capsaicin inhibits the reaction [Freund's Adjuvant results in increased expression of TAC1 mRNA]; Capsaicin inhibits the reaction [Potassium results in increased secretion of TAC1 protein modified form]; Capsaicin results in increased expression of and results in increased secretion of TAC1 protein; capsazepine inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]; capsazepine inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; cochinchinenin inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]; Colforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; CP 96345 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; dragon's blood inhibits the reaction [Capsaicin results in increased secretion of TAC1 protein]; Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Gabapentin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; GAL protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]; Go 6976 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; HU 211 inhibits the reaction [Colforsin promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; HU 211 inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Iloprost promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Indomethacin inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Indomethacin inhibits the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; KNG1 protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Morphine promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; NGF protein promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Pregabalin inhibits the reaction [Freund's Adjuvant promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; Pregabalin inhibits the reaction [Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; pyrazolanthrone promotes the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; SB 203580 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]; U 0126 inhibits the reaction [GR 73632 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]]
Capsaicin results in decreased expression of TAC1 mRNA; Capsaicin results in decreased expression of TAC1 protein
[Capsaicin co-treated with CCK protein alternative form] results in increased expression of TAC1 protein; Capsaicin inhibits the reaction [sodium arsenite results in increased secretion of TAC1 protein]; SCN10A protein affects the reaction [Capsaicin results in increased secretion of TAC1 protein alternative form]; TAC1 protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]
Capsaicin results in decreased secretion of TAC1 protein
TAC1 protein results in decreased activity of Capsaicin		 CTD PMID:2325850 PMID:2480171 PMID:3412491 PMID:6205719 PMID:7473211 More... NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834 		JBrowse link
G Tac2 tachykinin 2 decreases expression ISO Capsaicin results in decreased expression of TAC2 mRNA CTD PMID:16278290 NCBI chr10:127,560,347...127,567,637
Ensembl chr10:127,560,347...127,567,637 		JBrowse link
G Tacr1 tachykinin receptor 1 decreases expression
increases response to substance
affects expression
multiple interactions
increases expression		 EXP
ISO		 Capsaicin results in decreased expression of TACR1 mRNA; Capsaicin results in decreased expression of TACR1 protein
TACR1 results in increased susceptibility to Capsaicin
Capsaicin affects the expression of TACR1 mRNA
Capsaicin affects the reaction [Vehicle Emissions affects the expression of TACR1 mRNA]; Capsaicin inhibits the reaction [[1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TACR1 mRNA]; Capsaicin promotes the reaction [Vehicle Emissions results in increased expression of TACR1 protein]
Capsaicin results in increased expression of TACR1 protein		 CTD PMID:10360863 PMID:11166975 PMID:13680092 PMID:18441096 PMID:19399481 More... NCBI chr 6:82,378,990...82,537,085
Ensembl chr 6:82,379,315...82,537,085 		JBrowse link
G Tacr2 tachykinin receptor 2 increases response to substance
decreases expression
multiple interactions		 ISO TACR2 gene polymorphism results in increased susceptibility to Capsaicin
Capsaicin results in decreased expression of TACR2 mRNA
Capsaicin inhibits the reaction [[1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TACR2 mRNA]		 CTD PMID:16278290 PMID:16893949 PMID:19399481 NCBI chr10:62,088,217...62,101,769
Ensembl chr10:62,088,217...62,101,769 		JBrowse link
G Tal1 T cell acute lymphocytic leukemia 1 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of TAL1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TAL1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TAL1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TAL1 protein]		 CTD PMID:22150557 NCBI chr 4:114,913,623...114,928,952
Ensembl chr 4:114,913,623...114,928,952 		JBrowse link
G Tek TEK receptor tyrosine kinase increases expression
multiple interactions		 ISO Capsaicin results in increased expression of TEK protein
Capsaicin results in increased expression of TEK mRNA
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TEK protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TEK protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TEK protein]		 CTD PMID:21310942 PMID:22150557 NCBI chr 4:94,627,322...94,763,213
Ensembl chr 4:94,627,526...94,763,213 		JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO Capsaicin results in increased expression of TGFA mRNA; Capsaicin results in increased expression of TGFA protein CTD PMID:11989832 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
multiple interactions
increases expression		 ISO Capsaicin results in decreased expression of TGFB1 mRNA
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TGFB1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TGFB1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TGFB1 protein]		 CTD PMID:18533110 PMID:22150557 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of TGFB2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TGFB2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TGFB2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TGFB2 protein]		 CTD PMID:22150557 NCBI chr 1:186,354,984...186,441,504
Ensembl chr 1:186,354,989...186,438,186 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 multiple interactions
increases expression		 ISO [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TGFB3 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TGFB3 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TGFB3 protein] CTD PMID:22150557 NCBI chr12:86,103,517...86,125,815
Ensembl chr12:86,103,519...86,125,815 		JBrowse link
G Thop1 thimet oligopeptidase 1 increases expression ISO Capsaicin results in increased expression of THOP1 mRNA CTD PMID:16278290 NCBI chr10:80,905,917...80,918,194
Ensembl chr10:80,905,869...80,918,393 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of TIMP1 mRNA
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein]		 CTD PMID:21310942 PMID:22150557 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974 		JBrowse link
G Timp2 tissue inhibitor of metalloproteinase 2 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of TIMP2 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP2 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TIMP2 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TIMP2 protein]		 CTD PMID:22150557 NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566 		JBrowse link
G Timp3 tissue inhibitor of metalloproteinase 3 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of TIMP3 mRNA
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP3 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TIMP3 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TIMP3 protein]		 CTD PMID:21310942 PMID:22150557 NCBI chr10:86,136,276...86,185,369
Ensembl chr10:86,136,236...86,185,370 		JBrowse link
G Tlr4 toll-like receptor 4 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of TLR4 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TLR4 protein]		 CTD PMID:22150557 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 decreases expression ISO Capsaicin results in decreased expression of TM7SF2 mRNA CTD PMID:18533110 NCBI chr19:6,112,851...6,117,880
Ensembl chr19:6,112,851...6,118,403 		JBrowse link
G Tmem37 transmembrane protein 37 increases expression ISO Capsaicin results in increased expression of TMEM37 mRNA CTD PMID:16278290 NCBI chr 1:119,995,106...120,001,799
Ensembl chr 1:119,995,107...120,001,804 		JBrowse link
G Tnc tenascin C decreases expression ISO Capsaicin results in decreased expression of TNC mRNA CTD PMID:33512557 NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252 		JBrowse link
G Tnf tumor necrosis factor decreases secretion
affects response to substance
increases response to substance
multiple interactions
increases expression
increases secretion
decreases expression		 EXP
ISO		 Capsaicin results in decreased secretion of TNF protein
TNF protein affects the susceptibility to Capsaicin
TNF protein results in increased susceptibility to Capsaicin
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased secretion of TNF protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Capsaicin results in increased secretion of TNF protein]; bisindolylmaleimide inhibits the reaction [Capsaicin results in increased secretion of TNF protein]; CALCA protein alternative form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; Capsaicin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Capsaicin inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; Capsaicin inhibits the reaction [TNF protein results in increased expression of GSTP1 mRNA]; Capsaicin promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; capsazepine inhibits the reaction [Capsaicin results in increased secretion of TNF protein]
Capsaicin results in increased expression of TNF mRNA
Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]
[Capsaicin results in increased susceptibility to Formaldehyde] which results in increased expression of TNF mRNA; [Capsaicin results in increased susceptibility to Glyoxal] which results in increased expression of TNF mRNA; [Lipopolysaccharides co-treated with Capsaicin] results in increased expression of TNF protein; [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of TNF mRNA]; Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Capsaicin inhibits the reaction [monophosphoryl lipid A results in decreased expression of TNF protein]; Capsaicin inhibits the reaction [Nitroglycerin results in decreased expression of TNF protein]; capsazepine inhibits the reaction [Capsaicin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Ketotifen inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TNF protein]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF mRNA]; NOX3 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Ranitidine inhibits the reaction [Capsaicin results in increased expression of TNF protein]; spantide II inhibits the reaction [Capsaicin results in increased expression of TNF protein]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF mRNA]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TNF protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TNF protein]
Capsaicin results in decreased expression of TNF mRNA; Capsaicin results in decreased expression of TNF protein
Capsaicin results in increased expression of TNF mRNA; Capsaicin results in increased expression of TNF protein		 CTD PMID:11408036 PMID:11744139 PMID:12024109 PMID:12034025 PMID:15265675 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b increases expression ISO Capsaicin results in increased expression of TNFRSF10A mRNA; Capsaicin results in increased expression of TNFRSF10A protein CTD PMID:19502594 PMID:19846903 NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860 		JBrowse link
G Tnfrsf19 tumor necrosis factor receptor superfamily, member 19 affects expression
multiple interactions		 ISO Capsaicin affects the expression of TNFRSF19 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin affects the expression of TNFRSF19 protein]; Naproxen inhibits the reaction [Capsaicin affects the expression of TNFRSF19 protein]; Sumatriptan inhibits the reaction [Capsaicin affects the expression of TNFRSF19 protein]		 CTD PMID:22150557 NCBI chr14:61,201,283...61,284,304
Ensembl chr14:61,201,324...61,283,939 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a increases expression
multiple interactions		 ISO
EXP		 Capsaicin results in increased expression of TNFRSF1A mRNA
Capsaicin results in increased expression of TNFRSF1A protein
capsazepine inhibits the reaction [Capsaicin results in increased expression of TNFRSF1A protein]; phenyl-N-tert-butylnitrone inhibits the reaction [Capsaicin results in increased expression of TNFRSF1A protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of TNFRSF1A protein]		 CTD PMID:19531269 PMID:21310942 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnfrsf25 tumor necrosis factor receptor superfamily, member 25 increases expression ISO Capsaicin results in increased expression of TNFRSF25 mRNA CTD PMID:19502594 NCBI chr 4:152,199,985...152,204,568
Ensembl chr 4:152,200,391...152,204,576 		JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 multiple interactions
increases activity
increases expression
increases response to substance		 ISO [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP2 protein; [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP6 protein; [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP7 protein; [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP8 protein; [Capsaicin co-treated with TNFSF10 protein] results in increased cleavage of CASP9 protein; BIRC5 results in decreased activity of [Capsaicin co-treated with TNFSF10 protein]; Capsaicin promotes the reaction [SP1 protein binds to TNFSF10 promoter]; Capsaicin promotes the reaction [TNFSF10 protein results in increased cleavage of CASP3 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP3 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP8 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased activity of CASP9 protein]; Capsaicin promotes the reaction [TNFSF10 results in increased cleavage of BID protein]; Capsaicin promotes the reaction [TNFSF10 results in increased cleavage of PARP1 protein]; Egtazic Acid inhibits the reaction [Capsaicin results in increased expression of TNFSF10 mRNA]; staurosporine aglycone inhibits the reaction [Capsaicin results in increased expression of TNFSF10 mRNA]; TNFRSF10B mutant form inhibits the reaction [Capsaicin results in increased susceptibility to TNFSF10 protein]
Capsaicin results in increased activity of TNFSF10 protein
Capsaicin results in increased expression of TNFSF10 mRNA; Capsaicin results in increased expression of TNFSF10 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TNFSF10 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of TNFSF10 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TNFSF10 protein]		 CTD PMID:19939880 PMID:22150557 PMID:22200406 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576 		JBrowse link
G Tom1 target of myb1 trafficking protein decreases expression ISO Capsaicin results in decreased expression of TOM1 mRNA CTD PMID:20349343 NCBI chr 8:75,760,326...75,796,749
Ensembl chr 8:75,760,333...75,796,749 		JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO Capsaicin results in increased expression of TPI1 mRNA; Capsaicin results in increased expression of TPI1 protein CTD PMID:19891501 NCBI chr 6:124,787,549...124,791,121
Ensembl chr 6:124,787,549...124,791,259 		JBrowse link
G Traf3 TNF receptor-associated factor 3 increases expression ISO Capsaicin results in increased expression of TRAF3 mRNA CTD PMID:19502594 NCBI chr12:111,132,799...111,233,589
Ensembl chr12:111,132,804...111,233,587 		JBrowse link
G Traf4 TNF receptor associated factor 4 increases expression ISO Capsaicin results in increased expression of TRAF4 mRNA CTD PMID:19502594 NCBI chr11:78,049,249...78,056,405
Ensembl chr11:78,049,325...78,056,415 		JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 increases expression ISO Capsaicin results in increased expression of TRAFD1 mRNA CTD PMID:16278290 NCBI chr 5:121,509,788...121,524,543
Ensembl chr 5:121,509,788...121,523,695 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Capsaicin results in increased expression of TRIB3 mRNA CTD PMID:36044967 NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952 		JBrowse link
G Triml1 tripartite motif family-like 1 increases expression ISO Capsaicin results in increased expression of TRIML1 mRNA CTD PMID:36044967 NCBI chr 8:43,582,843...43,633,531
Ensembl chr 8:43,582,844...43,594,523 		JBrowse link
G Trp53 transformation related protein 53 decreases degradation
increases expression
increases degradation
multiple interactions
increases phosphorylation
affects response to substance		 ISO
EXP		 Capsaicin results in decreased degradation of TP53 protein
Capsaicin results in increased expression of TRP53
Capsaicin results in increased degradation of TP53 protein
Capsaicin results in increased expression of TP53 mRNA; Capsaicin results in increased expression of TP53 protein
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased expression of TP53 protein]; 3-aminobenzamide inhibits the reaction [Capsaicin results in increased expression of TP53 protein]; 3-aminobenzamide inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in increased degradation of TP53 protein]; Caffeine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]; Capsaicin promotes the reaction [resveratrol results in increased expression of TP53 protein]; Capsaicin results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein; Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein; Capsaicin results in increased phosphorylation of and results in increased expression of TP53 protein; CAT protein inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]; MAPK8 protein promotes the reaction [Capsaicin results in decreased degradation of TP53 protein]; pifithrin inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of TP53 protein]; pyrazolanthrone inhibits the reaction [Capsaicin results in increased expression of and results in increased phosphorylation of and results in increased activity of TP53 protein]; resveratrol promotes the reaction [Capsaicin results in increased expression of TP53 protein]; TP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS2 protein]]; TP53 affects the reaction [Capsaicin promotes the reaction [resveratrol results in increased expression of NOS3 protein]]; TP53 affects the reaction [Capsaicin results in decreased expression of MDM2 protein]; TP53 affects the reaction [Capsaicin results in increased expression of NOS1 protein]; TP53 affects the reaction [Capsaicin results in increased expression of NOS3 protein]; TP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS2 protein]]; TP53 affects the reaction [resveratrol promotes the reaction [Capsaicin results in increased expression of NOS3 protein]]; TP53 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]; Tunicamycin promotes the reaction [Capsaicin results in increased degradation of TP53 protein]
TP53 affects the susceptibility to Capsaicin		 CTD PMID:9461043 PMID:14871840 PMID:16540674 PMID:17292493 PMID:18991268 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Trp53inp2 transformation related protein 53 inducible nuclear protein 2 increases expression ISO Capsaicin results in increased expression of TP53INP2 mRNA CTD PMID:36044967 NCBI chr 2:155,223,742...155,231,767
Ensembl chr 2:155,222,979...155,231,770 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions
decreases expression
increases activity		 ISO Calcium affects the reaction [Capsaicin inhibits the reaction [TRPA1 protein affects the susceptibility to mustard oil]]
Capsaicin results in decreased expression of TRPA1 mRNA
Capsaicin results in increased activity of TRPA1 protein		 CTD PMID:17590514 PMID:18079164 PMID:29054683 NCBI chr 1:14,942,868...14,989,086
Ensembl chr 1:14,942,872...14,989,086 		JBrowse link
G Trpc5 transient receptor potential cation channel, subfamily C, member 5 increases expression ISO Capsaicin results in increased expression of TRPC5 mRNA CTD PMID:16278290 NCBI chr  X:143,160,323...143,471,176
Ensembl chr  X:143,164,667...143,471,176 		JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 decreases expression
increases activity		 ISO Capsaicin results in decreased expression of TRPM8 mRNA
Capsaicin results in increased activity of TRPM8 protein		 CTD PMID:18079164 PMID:29054683 NCBI chr 1:88,234,457...88,318,909
Ensembl chr 1:88,205,383...88,317,015 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 affects response to substance
decreases response to substance
increases response to substance
multiple interactions
affects binding
decreases expression
increases activity
increases expression
affects localization		 ISO
EXP		 TRPV1 protein affects the susceptibility to Capsaicin; TRPV1 protein polymorphism affects the susceptibility to Capsaicin analog
TRPV1 protein mutant form results in decreased susceptibility to Capsaicin; TRPV1 results in decreased susceptibility to Capsaicin
TRPV1 protein results in increased susceptibility to Capsaicin; TRPV1 results in increased susceptibility to Capsaicin
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; CALCA protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]; Capsaicin binds to and results in increased activity of TRPV1 protein; capsazepine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; CYBB protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]; Linolenic Acids inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; RARRES2 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; RTKI cpd inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; TAC1 protein affects the reaction [TRPV1 protein results in increased susceptibility to Capsaicin]; TRPV1 gene mutant form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]; TRPV1 gene mutant form inhibits the reaction [Capsaicin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; TRPV1 gene mutant form inhibits the reaction [Capsaicin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in decreased expression of LRP1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased abundance of Reactive Oxygen Species]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of ABCA1 protein]; TRPV1 gene mutant form inhibits the reaction [Capsaicin results in increased expression of TNFRSF1A protein]; TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]; TRPV1 mutant form inhibits the reaction [Capsaicin results in increased abundance of Reactive Oxygen Species]; TRPV1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; TRPV1 protein affects the reaction [Capsaicin results in increased transport of Calcium]; TRPV1 results in decreased susceptibility to [Capsaicin co-treated with Tetradecanoylphorbol Acetate]; U 0126 inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]
1-Methyl-3-isobutylxanthine promotes the reaction [Capsaicin results in increased activity of TRPV1]; 2,3-bis(4-hydroxyphenyl)-propionitrile inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 2,4-bis(4'-fluorophenethylamino)-6-(3'-(N,N-dimethylamino)propylamino)-1,3,5-triazine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 3-amino-5-((2-((2-methoxyethyl)amino)-6-(4-(trifluoromethyl)phenyl)pyrimidin-4-yl)oxy)quinoxalin-2(1H)-one inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP promotes the reaction [Capsaicin results in increased activity of TRPV1]; [Capsaicin binds to and affects the activity of TRPV1 protein] which results in increased secretion of Adenosine Triphosphate; [Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Cobalt; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; Acrylamide analog inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Amitriptyline inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; benzimidazole analog inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Bupivacaine affects the reaction [Capsaicin results in increased activity of TRPV1 protein]; Butyrates promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Butyrates promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Cadmium inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Calcium affects the reaction [Capsaicin inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; Calcium affects the reaction [mustard oil inhibits the reaction [TRPV1 protein affects the susceptibility to Capsaicin]]; Capsaicin binds to and results in increased activity of TRPV1 protein; Capsaicin inhibits the reaction [[1,2-naphthoquinone co-treated with Vehicle Emissions] results in increased expression of TRPV1 mRNA]; Capsaicin promotes the reaction [adenosine 5'-O-(3-thiotriphosphate) results in increased activity of TRPV1 protein]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; Capsaicin promotes the reaction [TRPV1 protein binds to TRPV1 protein]; capsazepine inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Cobalt]; capsazepine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; chelerythrine inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein]; Cobalt inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Colforsin promotes the reaction [Capsaicin results in increased activity of TRPV1]; Copper inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Docosahexaenoic Acids promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Eicosapentaenoic Acid inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Estradiol inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Fulvestrant inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; gamma-Linolenic Acid inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; geldanamycin affects the reaction [Capsaicin results in increased activity of TRPV1]; iodoresiniferatoxin inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein]; JYL 1421 inhibits the reaction [Capsaicin binds to TRPV1 protein]; JYL 1421 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; KJM 429 inhibits the reaction [Capsaicin binds to TRPV1 protein]; Lidocaine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; MCS-18 inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; N-((4-(((3-(6-((2-amino-1,3-benzothiazol-4-yl)oxy)pyrimidin-4-yl)) -6-(trifluoromethyl)pyridin-2-yl)amino)methyl)-2-fluorophenyl)methanesulfonamide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Nickel inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Octoxynol inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; oxophenylarsine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; oxophenylarsine inhibits the reaction [Lidocaine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]; Ruthenium Red inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; Ruthenium Red inhibits the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Cobalt]; Serotonin promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased transport of Calcium]; STAT1 mutant form inhibits the reaction [Capsaicin results in increased expression of TRPV1 protein]; Tamoxifen inhibits the reaction [2,3-bis(4-hydroxyphenyl)-propionitrile inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]]; Tamoxifen inhibits the reaction [Estradiol inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]]; tert-butyl-2-(6-((2-(acetylamino)-1,3-benzothiazol-4-yl)oxy)pyrimidin-4-yl)-5-(trifluoromethyl)phenylcarbamate inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; Tetracaine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; TRPV1 protein affects the reaction [Capsaicin results in increased secretion of CALCA protein]
1-Methyl-3-isobutylxanthine promotes the reaction [Capsaicin results in increased activity of TRPV1]; 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP promotes the reaction [Capsaicin results in increased activity of TRPV1]; [Capsaicin binds to and results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased import of Calcium; [Capsaicin results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; [Capsaicin results in increased activity of TRPV1] which results in increased uptake of Calcium; BDKRB2 affects the reaction [Capsaicin results in increased activity of TRPV1 protein]; BDKRB2 affects the reaction [KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]]; Cannabidiol inhibits the reaction [[Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [Capsaicin binds to TRPV1 protein]; Capsaicin binds to and results in increased activity of TRPV1 protein; Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]; Capsaicin promotes the reaction [TRPV1 protein results in increased activity of CASP3 protein]; Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]; capsazepine inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; capsazepine inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; capsazepine inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Phosphatidylinositol 4,5-Diphosphate affects the reaction [Capsaicin results in increased activity of TRPV1 protein]]; capsazepine promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Colforsin promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Colforsin promotes the reaction [Capsaicin results in increased activity of TRPV1]; Edetic Acid inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; EDN1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Egtazic Acid inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; iodoresiniferatoxin inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; KNG1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Phosphatidylinositol 4,5-Diphosphate affects the reaction [Capsaicin results in increased activity of TRPV1 protein]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]]; Rimonabant inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; Ruthenium Red inhibits the reaction [Capsaicin promotes the reaction [TRPV1 protein results in increased abundance of Calcium]]; Tetradecanoylphorbol Acetate inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1 mRNA]; TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1R mRNA]; TRPV1 inhibits the reaction [Capsaicin results in increased expression of and results in increased activity of MMP9 protein]; TRPV1 promotes the reaction [Capsaicin results in increased uptake of Calcium]; TRPV1 protein promotes the reaction [Capsaicin results in increased expression of IL6 mRNA]; TRPV1 protein promotes the reaction [Capsaicin results in increased expression of IL6 protein]; Xenon inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]
Capsaicin results in decreased expression of TRPV1 mRNA; Capsaicin results in decreased expression of TRPV1 protein
Capsaicin analog results in increased activity of TRPV1 protein; Capsaicin results in increased activity of TRPV1; Capsaicin results in increased activity of TRPV1 protein
Capsaicin results in increased expression of TRPV1 mRNA; Capsaicin results in increased expression of TRPV1 protein
Capsaicin affects the localization of TRPV1 protein
TRPV1 protein results in increased susceptibility to Capsaicin; TRPV1 protein results in increased susceptibility to Capsaicin analog		 CTD PMID:11140687 PMID:11278420 PMID:11358970 PMID:11606325 PMID:11930156 More... NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases expression ISO Capsaicin results in increased expression of TRPV4 mRNA CTD PMID:16278290 NCBI chr 5:114,760,213...114,796,497
Ensembl chr 5:114,760,213...114,796,482 		JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 multiple interactions
increases response to substance		 ISO TRPV6 protein promotes the reaction [Capsaicin results in increased abundance of Calcium]; TRPV6 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]
TRPV6 protein results in increased susceptibility to Capsaicin		 CTD PMID:17292493 NCBI chr 6:41,597,553...41,613,339
Ensembl chr 6:41,597,558...41,613,339 		JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO Capsaicin results in decreased expression of TXNIP mRNA CTD PMID:33512557 NCBI chr 3:96,465,273...96,469,173
Ensembl chr 3:96,465,273...96,469,199 		JBrowse link
G Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) decreases expression
multiple interactions		 ISO Capsaicin results in decreased expression of UCP1 mRNA; Capsaicin results in decreased expression of UCP1 protein
Capsaicin promotes the reaction [Dietary Fats results in increased expression of UCP1 mRNA]		 CTD PMID:18079164 PMID:20359164 NCBI chr 8:84,016,977...84,025,085
Ensembl chr 8:84,016,981...84,025,081 		JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) affects response to substance
multiple interactions		 ISO UCP2 protein polymorphism affects the susceptibility to Capsaicin analog
Capsaicin inhibits the reaction [Dietary Fats results in decreased expression of UCP2 mRNA]		 CTD PMID:19056576 PMID:20359164 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227 		JBrowse link
G Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) multiple interactions ISO Capsaicin inhibits the reaction [Dietary Fats results in increased expression of UCP3 protein] CTD PMID:20517883 NCBI chr 7:100,122,198...100,135,639
Ensembl chr 7:100,122,197...100,135,639 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of Capsaicin CTD PMID:14557274 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 increases glucuronidation ISO UGT1A10 protein results in increased glucuronidation of Capsaicin CTD PMID:14557274 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of Capsaicin CTD PMID:14557274 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
G Ulk1 unc-51 like kinase 1 increases expression ISO Capsaicin results in increased expression of ULK1 mRNA CTD PMID:36044967 NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963 		JBrowse link
G Unc13a unc-13 homolog A increases expression ISO Capsaicin results in increased expression of UNC13A mRNA CTD PMID:16278290 NCBI chr 8:72,079,356...72,124,418
Ensembl chr 8:72,077,061...72,124,401 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 (isopeptidase T) decreases expression ISO Capsaicin results in decreased expression of USP5 mRNA CTD PMID:20349343 NCBI chr 6:124,791,982...124,806,404
Ensembl chr 6:124,791,982...124,806,447 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 decreases expression ISO Capsaicin results in decreased expression of VAMP2 mRNA CTD PMID:20349343 NCBI chr11:68,979,354...68,983,207
Ensembl chr11:68,979,316...68,983,210 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression
multiple interactions		 ISO Capsaicin results in increased expression of VCAM1 protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of VCAM1 protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of VCAM1 protein]; Sumatriptan inhibits the reaction [Capsaicin results in increased expression of VCAM1 protein]		 CTD PMID:9973426 PMID:22150557 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
decreases activity
increases secretion
multiple interactions
increases expression		 ISO
EXP		 Capsaicin results in decreased expression of VEGFA protein
Capsaicin results in decreased activity of VEGFA
Capsaicin results in increased secretion of VEGFA protein
[Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of VEGFA protein]; Naproxen inhibits the reaction [Capsaicin results in increased expression of VEGFA protein]; Sumatriptan affects the reaction [Capsaicin results in increased expression of VEGFA protein]
Capsaicin results in increased expression of VEGFA mRNA		 CTD PMID:12242509 PMID:14744780 PMID:17505005 PMID:21310942 PMID:22150557 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295 		JBrowse link
G Vim vimentin multiple interactions
decreases expression		 ISO Capsaicin inhibits the reaction [Dietary Fats results in increased expression of VIM protein]
Capsaicin results in decreased expression of VIM protein		 CTD PMID:20359164 PMID:36044967 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637 		JBrowse link
G Vip vasoactive intestinal polypeptide decreases expression
increases expression		 ISO Capsaicin results in decreased expression of VIP mRNA
Capsaicin results in increased expression of VIP mRNA		 CTD PMID:8971780 PMID:20349343 NCBI chr10:5,589,131...5,597,617
Ensembl chr10:5,589,218...5,597,617 		JBrowse link
G Wnt7a wingless-type MMTV integration site family, member 7A decreases expression ISO Capsaicin results in decreased expression of WNT7A mRNA CTD PMID:16278290 NCBI chr 6:91,340,963...91,388,335
Ensembl chr 6:91,340,963...91,388,345 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A increases expression ISO Capsaicin results in increased expression of ZC3H12A mRNA CTD PMID:36044967 NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633 		JBrowse link
G Zfp2 zinc finger protein 2 increases expression ISO Capsaicin results in increased expression of ZFP2 mRNA CTD PMID:16278290 NCBI chr11:50,788,092...50,807,043
Ensembl chr11:50,789,539...50,806,992 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22205
    role 22190
      biological role 22189
        pharmacological role 19801
          agonist 19253
            TRPV1 agonist 519
              capsaicin 518
Path 2
Term Annotations click to browse term
  CHEBI ontology 22205
    subatomic particle 22197
      composite particle 22197
        hadron 22197
          baryon 22197
            nucleon 22169
              atomic nucleus 22197
                atom 22197
                  main group element atom 22131
                    p-block element atom 22131
                      carbon group element atom 21928
                        carbon atom 21854
                          organic molecular entity 21854
                            heteroorganic entity 21512
                              organochalcogen compound 21001
                                organooxygen compound 20845
                                  carbon oxoacid 19638
                                    carboxylic acid 19631
                                      carboacyl group 18297
                                        univalent carboacyl group 18297
                                          carbamoyl group 18111
                                            carboxamide 18111
                                              monocarboxylic acid amide 15838
                                                fatty amide 822
                                                  capsaicinoid 520
                                                    capsaicin 518
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