(-)-epigallocatechin 3-gallate multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 epigallocatechin gallate promotes the reaction [Warfarin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of RPS6KB1 protein]] CTD PMID:36162953 (-)-gambogic acid decreases activity ISO RPS6KB1 (Homo sapiens) 6480464 gambogic acid results in decreased activity of RPS6KB1 protein CTD PMID:19433130 (S)-nicotine increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Nicotine results in increased phosphorylation of RPS6KB1 protein CTD PMID:30259641 (S)-nicotine multiple interactions EXP 6480464 Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:31926917 (S)-nicotine multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:30259641 and PMID:31926917 1,1'-azobis(N,N-dimethylformamide) increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Diamide results in increased phosphorylation of RPS6KB1 protein CTD PMID:16183647 1,1'-azobis(N,N-dimethylformamide) multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Diamide results in increased activity of MTOR protein] which results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:16183647 1,2-dichloroethane decreases expression EXP 6480464 ethylene dichloride results in decreased expression of RPS6KB1 mRNA CTD PMID:28960355 1,2-dimethylhydrazine affects expression EXP 6480464 1 and 2-Dimethylhydrazine affects the expression of RPS6KB1 mRNA CTD PMID:22206623 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Penfluridol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35530161 1-octadec-9-enoylglycero-3-phosphate increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein CTD PMID:17919812 1-octadec-9-enoylglycero-3-phosphate increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein CTD PMID:14769825 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein] CTD PMID:17919812 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:14769825 14,15-EET increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 14 more ... CTD PMID:16286479 14-Deoxy-11,12-didehydroandrographolide multiple interactions EXP 6480464 14-deoxy-11 more ... CTD PMID:30248417 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions EXP 6480464 [15-deoxy-delta(12 more ... CTD PMID:16611854 17beta-estradiol increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Estradiol results in increased phosphorylation of RPS6KB1 protein CTD PMID:16033851 and PMID:31614463 17beta-estradiol multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of RPS6KB1 protein CTD PMID:22465879 17beta-estradiol multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:16033851 more ... 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Dihydrotestosterone inhibits the reaction [FSHB protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:17510244 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:29264491 2,2',4,4'-Tetrabromodiphenyl ether increases phosphorylation EXP 6480464 2 more ... CTD PMID:29264491 2,3',4,4',5-Pentachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of RPS6KB1 mRNA CTD PMID:33387578 2-amino-2-deoxy-D-glucopyranose decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Glucosamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19254699 2-deoxy-D-glucose decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Deoxyglucose results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16183647 2-deoxy-D-glucose multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Deoxyglucose results in increased phosphorylation of and results in increased activity of RPS6KB1 protein and oxophenylarsine inhibits the reaction [Deoxyglucose results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:16183647 and PMID:23041229 2-hydroxypropanoic acid decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of RPS6KB1 mRNA CTD PMID:30851411 3,3',5-triiodo-L-thyronine decreases phosphorylation EXP 6480464 Triiodothyronine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30209975 3,3',5-triiodo-L-thyronine multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:30209975 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 bisindolylmaleimide I inhibits the reaction [Phenylephrine results in increased activity of RPS6KB1 protein] CTD PMID:12720544 3-bromopyruvic acid increases expression ISO RPS6KB1 (Homo sapiens) 6480464 bromopyruvate results in increased expression of RPS6KB1 protein modified form CTD PMID:24307199 3-chloropropane-1,2-diol multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [[Diosgenin co-treated with alpha-Chlorohydrin] results in decreased phosphorylation of RPS6KB1 protein] and [Diosgenin co-treated with alpha-Chlorohydrin] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35149085 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of RPS6KB1 protein CTD PMID:33171136 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 14-deoxy-11 more ... CTD PMID:30248417 3-methyladenine decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 3-methyladenine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:26804764 3-methyladenine increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 3-methyladenine results in increased phosphorylation of RPS6KB1 protein CTD PMID:35149085 3-methyladenine multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [[Diosgenin co-treated with alpha-Chlorohydrin] results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:35149085 3H-1,2-dithiole-3-thione decreases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in decreased expression of RPS6KB1 mRNA CTD PMID:19162173 4'-epidoxorubicin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Gossypol inhibits the reaction [Epirubicin results in increased phosphorylation of RPS6KB1 protein] and MK 2206 inhibits the reaction [Epirubicin results in increased phosphorylation of RPS6KB1 protein] CTD PMID:35872041 4'-epidoxorubicin increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Epirubicin results in increased phosphorylation of RPS6KB1 protein CTD PMID:35872041 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of RPS6KB1 mRNA CTD PMID:18648102 4,4'-diaminodiphenylmethane decreases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of RPS6KB1 mRNA CTD PMID:30723492 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of RPS6KB1 protein CTD PMID:30259641 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased phosphorylation of RPS6KB1 protein CTD PMID:30259641 4-hydroxynon-2-enal increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of RPS6KB1 protein CTD PMID:19289642 4-hydroxyphenyl retinamide decreases expression EXP 6480464 Fenretinide results in decreased expression of RPS6KB1 mRNA CTD PMID:28973697 4-nonylphenol decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 4-nonylphenol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:26804764 and PMID:28041982 4-nonylphenol multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of RPS6KB1 protein] more ... CTD PMID:26804764 and PMID:28041982 4-tert-Octylphenol increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 4-tert-octylphenol results in increased phosphorylation of RPS6KB1 protein CTD PMID:32466334 5-aza-2'-deoxycytidine multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Decitabine inhibits the reaction [sodium arsenite results in increased phosphorylation of RPS6KB1 protein] CTD PMID:26432159 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:30209975 9-cis-retinoic acid multiple interactions EXP 6480464 [15-deoxy-delta(12 more ... CTD PMID:16611854 acadesine multiple interactions EXP 6480464 acadesine promotes the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:31982503 acetaldehyde increases activity ISO RPS6KB1 (Homo sapiens) 6480464 Acetaldehyde results in increased activity of RPS6KB1 protein CTD PMID:16962100 acetaldehyde multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Sirolimus inhibits the reaction [Acetaldehyde results in increased activity of RPS6KB1 protein] CTD PMID:16962100 acetylsalicylic acid multiple interactions EXP 6480464 Aspirin results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein CTD PMID:10993886 aconitine increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Aconitine results in increased expression of RPS6KB1 mRNA CTD PMID:28099878 acrolein decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Acrolein results in decreased expression of RPS6KB1 protein modified form CTD PMID:21742783 actinomycin D multiple interactions EXP 6480464 PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:14640974 actinomycin D multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:14640974 adenosine increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Adenosine results in increased phosphorylation of RPS6KB1 protein CTD PMID:34070360 AICA ribonucleotide multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 AICA ribonucleotide inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] and naringin inhibits the reaction [AICA ribonucleotide results in increased phosphorylation of RPS6KB1 protein] CTD PMID:15342961 and PMID:21195169 AICA ribonucleotide decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 AICA ribonucleotide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:28041982 AICA ribonucleotide increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 AICA ribonucleotide results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342961 aldehydo-D-glucosamine decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Glucosamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19254699 aldehydo-D-glucose multiple interactions EXP 6480464 HU 308 inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] and Sirolimus inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30459625 and PMID:35445903 aldehydo-D-glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of RPS6KB1 protein CTD PMID:30459625 Alisol B decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 alisol B results in decreased phosphorylation of RPS6KB1 protein CTD PMID:20197400 all-trans-retinoic acid decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Tretinoin results in decreased expression of RPS6KB1 mRNA and Tretinoin results in decreased expression of RPS6KB1 protein modified form CTD PMID:15498508 more ... alpha,alpha-trehalose multiple interactions EXP 6480464 Trehalose inhibits the reaction [Cholesterol inhibits the reaction [Cadmium Chloride results in increased cleavage of RPS6KB1 protein]] more ... CTD PMID:29486218 and PMID:32773031 alpha,alpha-trehalose decreases phosphorylation EXP 6480464 Trehalose results in decreased phosphorylation of RPS6KB1 protein CTD PMID:29486218 alpha-(methylamino)isobutyric acid multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 2-(methylamino)isobutyric acid inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein] CTD PMID:22215663 Alpinetin multiple interactions EXP 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein]] and alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein] CTD PMID:31676321 Alpinetin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]] more ... CTD PMID:31676321 alternariol decreases phosphorylation EXP 6480464 alternariol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25456271 amino acid multiple interactions EXP 6480464 [EIF2AK4 gene mutant form affects the susceptibility to Amino Acids deficiency] which results in increased phosphorylation of RPS6KB1 protein and Tunicamycin inhibits the reaction [[EIF2AK4 gene mutant form affects the susceptibility to Amino Acids deficiency] which results in increased phosphorylation of RPS6KB1 protein] CTD PMID:29449374 amiodarone decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Amiodarone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:23912912 and PMID:25881747 ammonium chloride affects expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of RPS6KB1 mRNA CTD PMID:16483693 ammonium chloride decreases phosphorylation EXP 6480464 Ammonium Chloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31310755 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone affects the reaction [flufenoxuron results in decreased phosphorylation of RPS6KB1 protein] more ... CTD PMID:20589738 more ... anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [Ketoglutaric Acids results in increased phosphorylation of RPS6KB1 protein] CTD PMID:31051157 anthra[1,9-cd]pyrazol-6(2H)-one decreases activity ISO RPS6KB1 (Homo sapiens) 6480464 pyrazolanthrone results in decreased activity of RPS6KB1 protein CTD PMID:12534346 ANTIMYCIN decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 antimycin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16183647 ANTIMYCIN multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 oxophenylarsine inhibits the reaction [antimycin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:16183647 apigenin decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Apigenin results in decreased expression of RPS6KB1 protein CTD PMID:15947208 arachidonic acid multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Arachidonic Acid promotes the reaction [Quercetin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:20551291 arsane multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:32802178 arsenic atom multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:32802178 arsenite(3-) multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 2-(methylamino)isobutyric acid inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:22215663 and PMID:31781319 arsenite(3-) increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 arsenite results in increased phosphorylation of RPS6KB1 protein CTD PMID:22215663 arsenite(3-) increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 arsenite results in increased phosphorylation of RPS6KB1 protein CTD PMID:17038550 and PMID:20377179 arsenite(3-) multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein] CTD PMID:20377179 arsenite(3-) increases phosphorylation EXP 6480464 arsenite results in increased phosphorylation of RPS6KB1 protein CTD PMID:22215663 and PMID:23396362 arsenite(3-) decreases phosphorylation EXP 6480464 arsenite results in decreased phosphorylation of RPS6KB1 protein CTD PMID:20589738 arsenite(3-) multiple interactions EXP 6480464 1 more ... CTD PMID:14516795 more ... arsenous acid decreases activity ISO RPS6KB1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased activity of RPS6KB1 protein CTD PMID:14633726 arsenous acid increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of RPS6KB1 protein and Arsenic Trioxide results in increased phosphorylation of S6K protein CTD PMID:18048359 and PMID:25758096 arsenous acid multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [lonidamine results in increased phosphorylation of RPS6KB1 protein] and Arsenic Trioxide inhibits the reaction [Sorafenib results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21889928 and PMID:25416439 arsenous acid decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of RPS6KB1 protein modified form CTD PMID:20574048 arsenous acid decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21594580 and PMID:25416439 atrazine decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Atrazine results in decreased expression of RPS6KB1 mRNA CTD PMID:22378314 aucubin increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 aucubin results in increased phosphorylation of RPS6KB1 protein CTD PMID:29408431 avobenzone increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 avobenzone results in increased phosphorylation of RPS6KB1 protein CTD PMID:29981360 azathioprine multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Azathioprine results in increased phosphorylation of RPS6KB1 protein] CTD PMID:23958494 azathioprine decreases phosphorylation EXP 6480464 Azathioprine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:23958494 azathioprine increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Azathioprine results in increased phosphorylation of RPS6KB1 protein CTD PMID:23958494 bafilomycin A1 decreases phosphorylation EXP 6480464 bafilomycin A1 results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31310755 bafilomycin A1 multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 bafilomycin A1 inhibits the reaction [EGF protein results in increased activity of and results in increased phosphorylation of RPS6KB1 protein] and bafilomycin A1 inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:22689575 baicalein multiple interactions EXP 6480464 baicalein results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein CTD PMID:24560969 BAPTA decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 1 more ... CTD PMID:16183647 BAPTA multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 oxophenylarsine inhibits the reaction [1 more ... CTD PMID:16183647 Bardoxolone methyl decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 bardoxolone methyl results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35929395 benzo[a]pyrene multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:32802178 benzo[a]pyrene diol epoxide I increases expression ISO RPS6KB1 (Homo sapiens) 6480464 7 more ... CTD PMID:26238291 benzofurans multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30696844 beta-D-glucosamine decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Glucosamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19254699 beta-thujaplicin decreases phosphorylation EXP 6480464 beta-thujaplicin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25044443 bicalutamide multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [bicalutamide co-treated with Testosterone] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21036700 bis(2-ethylhexyl) phthalate increases expression ISO RPS6KB1 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of RPS6KB1 mRNA and Diethylhexyl Phthalate results in increased expression of RPS6KB1 protein CTD PMID:23793038 bis(2-ethylhexyl) phthalate decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of RPS6KB1 protein CTD PMID:31163220 bis(2-ethylhexyl) phthalate multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Diethylhexyl Phthalate results in increased expression of RPS6KB1 mRNA] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Diethylhexyl Phthalate results in increased expression of RPS6KB1 protein] CTD PMID:23793038 bisphenol A increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of RPS6KB1 mRNA CTD PMID:25181051 more ... bisphenol A increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 bisphenol A results in increased phosphorylation of RPS6KB1 protein CTD PMID:32466334 and PMID:36232920 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of RPS6KB1 mRNA CTD PMID:33221593 bisphenol A decreases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of RPS6KB1 mRNA CTD PMID:27539358 bisphenol A decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 bisphenol A results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27296223 bisphenol A affects expression ISO Rps6kb1 (Rattus norvegicus) 6480464 bisphenol A affects the expression of RPS6KB1 mRNA CTD PMID:27296223 BMS-754807 decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 BMS 754807 results in decreased phosphorylation of RPS6KB1 protein CTD PMID:24986516 BMS-754807 multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [[CDK4 mutant form co-treated with CDK6 mutant form] results in increased susceptibility to BMS 754807] which results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:24986516 bortezomib increases expression ISO RPS6KB1 (Homo sapiens) 6480464 Bortezomib results in increased expression of RPS6KB1 mRNA CTD PMID:20977926 bromobenzene increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 bromobenzene results in increased expression of RPS6KB1 mRNA CTD PMID:15056800 bucladesine multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RPS6KB1 mRNA CTD PMID:20823114 butan-1-ol multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 1-Butanol inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] and 1-Butanol inhibits the reaction [PDGFB protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:15255942 and PMID:15919668 butan-1-ol multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 1-Butanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] and 1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein] CTD PMID:14769825 and PMID:15705590 butanal decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 butyraldehyde results in decreased expression of RPS6KB1 mRNA CTD PMID:26079696 Butylparaben decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 butylparaben results in decreased phosphorylation of RPS6KB1 protein CTD PMID:29319206 Butylparaben multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [butylparaben results in decreased phosphorylation of RPS6KB1 protein] and U 0126 inhibits the reaction [butylparaben results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:29319206 C.I. Natural Red 20 multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 shikonin promotes the reaction [Oxygen deficiency results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:28684144 cadmium atom increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Cadmium results in increased phosphorylation of RPS6KB1 protein CTD PMID:14499349 cadmium atom decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Cadmium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:32693121 cadmium atom multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Sirolimus inhibits the reaction [Cadmium results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21933187 cadmium atom decreases phosphorylation EXP 6480464 Cadmium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21767558 cadmium dichloride multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] more ... CTD PMID:21195169 more ... cadmium dichloride decreases phosphorylation EXP 6480464 Cadmium Chloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35843418 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of RPS6KB1 mRNA CTD PMID:35843418 cadmium dichloride increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:18021293 more ... cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:21544200 and PMID:24299490 cadmium dichloride increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:18021293 more ... cadmium dichloride decreases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased expression of RPS6KB1 mRNA CTD PMID:33453195 cadmium dichloride increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of RPS6KB1 mRNA CTD PMID:21297351 cadmium dichloride multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 1 more ... CTD PMID:18021293 more ... cadmium dichloride multiple interactions EXP 6480464 1 more ... CTD PMID:21544200 more ... caffeine decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Caffeine results in decreased expression of RPS6KB1 protein modified form CTD PMID:21081844 caffeine decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35688186 caffeine decreases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Caffeine results in decreased expression of RPS6KB1 protein modified form CTD PMID:21081844 calciol decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Cholecalciferol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:18628207 calcium atom multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form and dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form] CTD PMID:23680031 calcium atom multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein] CTD PMID:12935885 calcium(0) multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form and dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form] CTD PMID:23680031 calcium(0) multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein] CTD PMID:12935885 calyculin a increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 calyculin A results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342961 cannabidiol multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Cannabidiol co-treated with moringin] results in decreased expression of RPS6KB1 mRNA CTD PMID:30096889 cantharidin increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Cantharidin results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342961 capsaicin decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Capsaicin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22226932 capsaicin increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Capsaicin results in increased phosphorylation of RPS6KB1 mRNA CTD PMID:36044967 carbachol multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 1-Butanol inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] and Carbachol results in increased phosphorylation of and results in increased activity of RPS6KB1 protein CTD PMID:15255942 carbon disulfide affects phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Carbon Disulfide affects the phosphorylation of RPS6KB1 protein CTD PMID:27530093 celastrol multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 celastrol inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] and PTEN protein promotes the reaction [celastrol inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein]] CTD PMID:24111524 chloroquine multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Chloroquine inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:22689575 chloroquine increases expression EXP 6480464 Chloroquine results in increased expression of RPS6KB1 protein modified form CTD PMID:25884947 chloroquine decreases phosphorylation EXP 6480464 Chloroquine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31310755 cholesterol increases phosphorylation EXP 6480464 Cholesterol results in increased phosphorylation of RPS6KB1 protein CTD PMID:29486218 cholesterol multiple interactions EXP 6480464 Trehalose inhibits the reaction [Cholesterol inhibits the reaction [Cadmium Chloride results in increased cleavage of RPS6KB1 protein]] and Trehalose inhibits the reaction [Cholesterol results in increased phosphorylation of RPS6KB1 protein] CTD PMID:29486218 chromium atom multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:18569013 chromium atom decreases phosphorylation EXP 6480464 Chromium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:18569013 chromium(6+) multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Sirolimus inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30236763 chromium(6+) increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 chromium hexavalent ion results in increased phosphorylation of RPS6KB1 protein CTD PMID:30236763 chromium(6+) multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Sirolimus inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30236763 chromium(6+) increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 chromium hexavalent ion results in increased phosphorylation of RPS6KB1 protein CTD PMID:30236763 chrysophanol decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 chrysophanic acid results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30300626 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of RPS6KB1 mRNA CTD PMID:21151649 cisplatin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [cordycepin co-treated with Cisplatin] results in decreased phosphorylation of RPS6KB1 protein and [cordycepin co-treated with Cisplatin] results in decreased phosphorylation of S6K protein CTD PMID:33520990 cisplatin multiple interactions EXP 6480464 trichostatin A promotes the reaction [Cisplatin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:29476062 cisplatin multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 trichostatin A promotes the reaction [Cisplatin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:29476062 cisplatin decreases phosphorylation EXP 6480464 Cisplatin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:29476062 cisplatin decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Cisplatin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:29476062 clofibrate affects phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Clofibrate affects the phosphorylation of RPS6KB1 protein CTD PMID:16616211 cobalt dichloride increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 cobaltous chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:25446852 cobalt dichloride multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 [cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:24989011 cobalt dichloride multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Flavanones inhibits the reaction [cobaltous chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:25446852 copper atom multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of RPS6KB1 mRNA CTD PMID:30911355 copper(0) multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of RPS6KB1 mRNA CTD PMID:30911355 copper(II) chloride increases phosphorylation EXP 6480464 cupric chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:32512069 copper(II) chloride multiple interactions EXP 6480464 CALB1 protein inhibits the reaction [cupric chloride results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:37981210 copper(II) chloride decreases phosphorylation EXP 6480464 cupric chloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:37981210 copper(II) sulfate increases expression ISO RPS6KB1 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of RPS6KB1 mRNA CTD PMID:19549813 cordycepin increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 cordycepin results in increased phosphorylation of RPS6KB1 protein CTD PMID:34070360 cordycepin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [cordycepin co-treated with Cisplatin] results in decreased phosphorylation of RPS6KB1 protein and [cordycepin co-treated with Cisplatin] results in decreased phosphorylation of S6K protein CTD PMID:33520990 Corynoxine B decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 corynoxine B results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30578841 Corynoxine B multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 corynoxine B promotes the reaction [manganese chloride results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:30578841 coumarin decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 coumarin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35688186 crocidolite asbestos decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased expression of RPS6KB1 protein modified form CTD PMID:21570478 cucurbitacin E decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 cucurbitacin E results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27363783 cucurbitacin E multiple interactions EXP 6480464 cucurbitacin E inhibits the reaction [Thioacetamide results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27363783 curcumin decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Curcumin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:18790744 and PMID:34634291 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Thioacetamide results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27363783 curcumin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Curcumin analog inhibits the reaction [Oxygen deficiency results in increased phosphorylation of RPS6KB1 protein] CTD PMID:20554536 cycloheximide multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]] CTD PMID:22689575 cyfluthrin increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 cyfluthrin results in increased expression of RPS6KB1 mRNA and cyfluthrin results in increased expression of RPS6KB1 protein CTD PMID:36515635 cyfluthrin increases expression EXP 6480464 cyfluthrin results in increased expression of RPS6KB1 mRNA and cyfluthrin results in increased expression of RPS6KB1 protein CTD PMID:36515635 cyfluthrin decreases expression EXP 6480464 cyfluthrin results in decreased expression of RPS6KB1 protein modified form CTD PMID:36515635 cyfluthrin decreases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 cyfluthrin results in decreased expression of RPS6KB1 protein modified form CTD PMID:36515635 cypermethrin decreases phosphorylation EXP 6480464 cypermethrin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:37011868 D-glucose multiple interactions EXP 6480464 HU 308 inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] and Sirolimus inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30459625 and PMID:35445903 D-glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of RPS6KB1 protein CTD PMID:30459625 dactolisib decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 dactolisib results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21464613 daunorubicin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Sirolimus inhibits the reaction [Daunorubicin results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21898527 daunorubicin decreases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Daunorubicin results in decreased expression of RPS6KB1 mRNA CTD PMID:28099878 daunorubicin increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Daunorubicin results in increased phosphorylation of RPS6KB1 protein CTD PMID:21898527 deguelin decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 deguelin metabolite results in decreased expression of RPS6KB1 protein and deguelin results in decreased expression of RPS6KB1 protein CTD PMID:19139008 deguelin decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 deguelin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27255535 deoxynivalenol decreases phosphorylation EXP 6480464 deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34506767 deoxynivalenol multiple interactions EXP 6480464 lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:34506767 dexamethasone decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Dexamethasone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:15070696 dexamethasone decreases phosphorylation EXP 6480464 Dexamethasone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22733784 and PMID:22936724 dexamethasone multiple interactions EXP 6480464 14-deoxy-11 more ... CTD PMID:22733784 more ... dexamethasone multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein more ... CTD PMID:15070696 more ... dextran sulfate multiple interactions EXP 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein]] more ... CTD PMID:27611972 more ... dextran sulfate decreases phosphorylation EXP 6480464 Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27611972 and PMID:31926917 dextran sulfate increases phosphorylation EXP 6480464 Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein CTD PMID:31676321 dextran sulfate decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31926917 dextran sulfate multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 dorsomorphin inhibits the reaction [Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein]] and Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:31926917 diarsenic trioxide multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [lonidamine results in increased phosphorylation of RPS6KB1 protein] and Arsenic Trioxide inhibits the reaction [Sorafenib results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21889928 and PMID:25416439 diarsenic trioxide increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased phosphorylation of RPS6KB1 protein and Arsenic Trioxide results in increased phosphorylation of S6K protein CTD PMID:18048359 and PMID:25758096 diarsenic trioxide decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of RPS6KB1 protein modified form CTD PMID:20574048 diarsenic trioxide decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21594580 and PMID:25416439 diarsenic trioxide decreases activity ISO RPS6KB1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased activity of RPS6KB1 protein CTD PMID:14633726 dibenziodolium multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 diphenyleneiodonium inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:21984483 Dictamnine multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [dictamnine co-treated with Oxygen deficiency] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30266538 dieckol decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 dieckol results in decreased expression of RPS6KB1 protein CTD PMID:31291034 digitoxin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Digitoxin co-treated with Oxygen deficiency] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34717917 digitoxin decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Digitoxin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34717917 dihydrolipoic acid multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 dihydrolipoic acid inhibits the reaction [PDGFB protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21251946 Dihydrotanshinone I decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 dihydrotanshinone I results in decreased phosphorylation of RPS6KB1 protein CTD PMID:26282490 dimercaprol multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Dimercaprol inhibits the reaction [oxophenylarsine results in increased phosphorylation of RPS6KB1 protein] CTD PMID:16183647 Dinitramine decreases phosphorylation EXP 6480464 dinitramine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:33288293 dioscin decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 dioscin results in decreased expression of RPS6KB1 mRNA CTD PMID:29990575 diosgenin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [[Diosgenin co-treated with alpha-Chlorohydrin] results in decreased phosphorylation of RPS6KB1 protein] and [Diosgenin co-treated with alpha-Chlorohydrin] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35149085 dioxygen increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Oxygen deficiency results in increased phosphorylation of RPS6KB1 protein and Oxygen results in increased phosphorylation of RPS6KB1 protein CTD PMID:19587783 and PMID:20554536 dioxygen decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Oxygen deficiency results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34717917 dioxygen multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [dictamnine co-treated with Oxygen deficiency] results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:20554536 more ... dodecanoic acid multiple interactions EXP 6480464 lauric acid inhibits the reaction [deoxynivalenol results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:34506767 dopamine decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Dopamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19410601 dorsomorphin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 dorsomorphin inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein] more ... CTD PMID:23111315 more ... dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [14-deoxy-11 more ... CTD PMID:29859833 more ... dorsomorphin multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 dorsomorphin inhibits the reaction [4-nonylphenol results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:28041982 doxorubicin multiple interactions EXP 6480464 NRG1 protein affects the reaction [Doxorubicin affects the phosphorylation of RPS6KB1 protein] CTD PMID:15833803 doxorubicin decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of RPS6KB1 mRNA CTD PMID:29803840 doxorubicin affects expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Doxorubicin affects the expression of RPS6KB1 mRNA CTD PMID:28099878 doxorubicin increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Doxorubicin results in increased phosphorylation of RPS6KB1 protein CTD PMID:27666003 enzacamene increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 enzacamene results in increased phosphorylation of RPS6KB1 protein CTD PMID:30597193 erlotinib hydrochloride multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 resveratrol promotes the reaction [Erlotinib Hydrochloride results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:25895606 erlotinib hydrochloride decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Erlotinib Hydrochloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21655094 and PMID:25895606 ethanol multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Ethanol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein] CTD PMID:12935885 ethanol affects splicing EXP 6480464 Ethanol affects the splicing of RPS6KB1 mRNA CTD PMID:30319688 ethanol decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Ethanol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:17685400 ethanol decreases phosphorylation EXP 6480464 Ethanol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:18317950 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions EXP 6480464 Egtazic Acid inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] and Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:14516795 and PMID:21544200 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21544200 everolimus multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]] CTD PMID:24989011 everolimus multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Everolimus inhibits the reaction [Estradiol results in increased phosphorylation of RPS6KB1 protein] and Everolimus inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:16033851 and PMID:19567381 fasudil decreases activity ISO RPS6KB1 (Homo sapiens) 6480464 fasudil results in decreased activity of RPS6KB1 protein CTD PMID:10998351 fingolimod hydrochloride decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Fingolimod Hydrochloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25939952 flavanones decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Flavanones results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25446852 flavanones multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Flavanones inhibits the reaction [cobaltous chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:25446852 flavokawain B multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 TRIB3 protein affects the reaction [flavokawain B results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:30025493 flavokawain B decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 flavokawain B results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30025493 flavonoids increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Flavonoids results in increased expression of RPS6KB1 mRNA CTD PMID:18035473 flufenoxuron decreases phosphorylation EXP 6480464 flufenoxuron results in decreased phosphorylation of RPS6KB1 protein CTD PMID:33771252 flufenoxuron multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [flufenoxuron results in decreased phosphorylation of RPS6KB1 protein] more ... CTD PMID:33771252 flutamide increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Flutamide results in increased expression of RPS6KB1 mRNA CTD PMID:24136188 formaldehyde decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of RPS6KB1 mRNA CTD PMID:23649840 FR900359 decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of RPS6KB1 protein CTD PMID:37730182 frenolicin B decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 frenolicin B results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30661989 Fusaric acid increases phosphorylation EXP 6480464 Fusaric Acid results in increased phosphorylation of RPS6KB1 protein CTD PMID:32156565 galangin decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 galangin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25450235 gefitinib decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 gefitinib results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21655094 genistein decreases expression EXP 6480464 Genistein results in decreased expression of RPS6KB1 mRNA CTD PMID:24967385 Gingerenone A increases response to substance ISO RPS6KB1 (Homo sapiens) 6480464 RPS6KB1 protein results in increased susceptibility to gingerenone A CTD PMID:26242912 Gingerenone A multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 gingerenone A results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein CTD PMID:33050000 Gingerenone A multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 gingerenone A promotes the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30296358 Gingerenone A decreases activity ISO RPS6KB1 (Homo sapiens) 6480464 gingerenone A results in decreased activity of RPS6KB1 protein CTD PMID:26242912 Gingerenone A multiple interactions EXP 6480464 gingerenone A affects the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30296358 gingerol decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 gingerol results in decreased expression of RPS6KB1 protein modified form CTD PMID:28249781 ginsenoside Re increases phosphorylation EXP 6480464 ginsenoside Re results in increased phosphorylation of RPS6KB1 protein CTD PMID:17885204 glucose multiple interactions EXP 6480464 HU 308 inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] and Sirolimus inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30459625 and PMID:35445903 glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of RPS6KB1 protein CTD PMID:30459625 glutathione increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Glutathione deficiency results in increased expression of RPS6KB1 mRNA CTD PMID:15345336 glycerol 2-phosphate multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein more ... CTD PMID:23111315 glyphosate increases expression ISO RPS6KB1 (Homo sapiens) 6480464 Glyphosate results in increased expression of RPS6KB1 mRNA CTD PMID:31874349 glyphosate decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Glyphosate results in decreased expression of RPS6KB1 mRNA CTD PMID:31295307 gold atom multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in decreased expression of RPS6KB1 protein CTD PMID:27470402 gold(0) multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in decreased expression of RPS6KB1 protein CTD PMID:27470402 gossypol multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Gossypol inhibits the reaction [Epirubicin results in increased phosphorylation of RPS6KB1 protein] CTD PMID:35872041 hexadecanoic acid decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Palmitic Acid results in decreased phosphorylation of RPS6KB1 protein CTD PMID:28073184 hexadecanoic acid multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 [Palmitic Acid co-treated with sodium bisulfide] inhibits the reaction [INS protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:35577173 HU-308 multiple interactions EXP 6480464 HU 308 inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30459625 hydrogen peroxide decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19451193 hydrogen peroxide increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased phosphorylation of RPS6KB1 protein CTD PMID:36162953 hydrogen peroxide multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 epigallocatechin gallate promotes the reaction [Warfarin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of RPS6KB1 protein]] and Warfarin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of RPS6KB1 protein] CTD PMID:36162953 hydrogen peroxide multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 1-Butanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] more ... CTD PMID:15705590 and PMID:25304210 hydrogen peroxide increases expression ISO RPS6KB1 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of RPS6KB1 protein CTD PMID:18603805 hydrogen sulfide increases phosphorylation EXP 6480464 Hydrogen Sulfide results in increased phosphorylation of RPS6KB1 protein CTD PMID:31843631 IC-87114 decreases phosphorylation EXP 6480464 IC 87114 results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16179367 indometacin increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Indomethacin results in increased expression of RPS6KB1 mRNA CTD PMID:18299717 irinotecan multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Irinotecan co-treated with rucaparib] results in decreased expression of RPS6KB1 protein CTD PMID:30612311 isoprenaline increases phosphorylation EXP 6480464 Isoproterenol results in increased phosphorylation of RPS6KB1 protein CTD PMID:18812163 isoprenaline affects expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Isoproterenol affects the expression of RPS6KB1 mRNA CTD PMID:28099878 ivermectin decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Ivermectin results in decreased expression of RPS6KB1 protein CTD PMID:32959892 KN-93 multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21933187 L-ascorbic acid 2-phosphate multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] affects the phosphorylation of RPS6KB1 protein more ... CTD PMID:23111315 lead diacetate decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 lead acetate results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22811615 and PMID:32879255 lead nitrate increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 lead nitrate results in increased phosphorylation of RPS6KB1 protein CTD PMID:27762461 lead nitrate multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27762461 Licochalcone A decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 licochalcone A results in decreased expression of RPS6KB1 mRNA CTD PMID:30055311 Licochalcone B decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 licochalcone B results in decreased phosphorylation of RPS6KB1 protein CTD PMID:35948134 lonidamine increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 lonidamine results in increased phosphorylation of RPS6KB1 protein CTD PMID:21889928 lonidamine multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 arsenic trioxide inhibits the reaction [lonidamine results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21889928 LY294002 decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of RPS6KB1 protein modified form CTD PMID:23255002 LY294002 multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [EDN1 protein results in increased activity of RPS6KB1 protein] more ... CTD PMID:12411397 and PMID:14769825 LY294002 decreases phosphorylation EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16179367 LY294002 decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21976531 more ... LY294002 multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] more ... CTD PMID:15297429 more ... LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] more ... CTD PMID:14516795 more ... manganese atom multiple interactions EXP 6480464 [[manganese chloride results in increased abundance of Manganese] which co-treated with Sirolimus] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31690173 manganese(0) multiple interactions EXP 6480464 [[manganese chloride results in increased abundance of Manganese] which co-treated with Sirolimus] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31690173 manganese(II) chloride increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 manganese chloride results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342272 manganese(II) chloride multiple interactions EXP 6480464 [[manganese chloride results in increased abundance of Manganese] which co-treated with Sirolimus] results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31690173 manganese(II) chloride decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 manganese chloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30578841 manganese(II) chloride multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 corynoxine B promotes the reaction [manganese chloride results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:30578841 manganese(II) chloride decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 manganese chloride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:23604964 medroxyprogesterone acetate multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RPS6KB1 mRNA CTD PMID:20823114 metformin multiple interactions EXP 6480464 3-benzyl-5-((2-nitrophenoxy)methyl)dihydrofuran-2(3H)-one inhibits the reaction [Metformin inhibits the reaction [lipopolysaccharide more ... CTD PMID:29859833 metformin decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Metformin results in decreased expression of RPS6KB1 protein modified form CTD PMID:33838154 metformin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Paclitaxel co-treated with Metformin] results in decreased expression of RPS6KB1 mRNA and Metformin inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein] CTD PMID:29309887 and PMID:34432352 methamphetamine decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Methamphetamine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34374793 methidathion decreases expression EXP 6480464 methidathion results in decreased expression of RPS6KB1 mRNA CTD PMID:34813904 methotrexate increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Methotrexate results in increased expression of RPS6KB1 mRNA CTD PMID:15120968 methoxyacetic acid affects expression ISO Rps6kb1 (Rattus norvegicus) 6480464 methoxyacetic acid affects the expression of RPS6KB1 mRNA CTD PMID:20864626 metoprolol increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Metoprolol results in increased expression of RPS6KB1 mRNA CTD PMID:28099878 miconazole decreases expression EXP 6480464 Miconazole results in decreased expression of RPS6KB1 mRNA CTD PMID:27462272 microcystin-LR multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:26506538 more ... microcystin-LR increases phosphorylation EXP 6480464 cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein CTD PMID:31714646 microcystin-LR increases expression ISO RPS6KB1 (Homo sapiens) 6480464 cyanoginosin LR results in increased expression of RPS6KB1 protein modified form CTD PMID:28984034 microcystin-LR multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 naringin inhibits the reaction [cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein] CTD PMID:15342961 microcystin-LR increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342961 microcystin-LR increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 cyanoginosin LR results in increased phosphorylation of RPS6KB1 protein CTD PMID:26506538 and PMID:34432352 MK-2206 multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 MK 2206 inhibits the reaction [Epirubicin results in increased phosphorylation of RPS6KB1 protein] CTD PMID:35872041 ML-7 multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 ML 7 inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:16799973 ML-7 multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 ML 7 results in decreased susceptibility to [quinocetone results in increased phosphorylation of RPS6KB1 protein] CTD PMID:26446980 morin increases expression ISO RPS6KB1 (Homo sapiens) 6480464 morin results in increased expression of RPS6KB1 mRNA CTD PMID:28689916 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide decreases activity ISO RPS6KB1 (Homo sapiens) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of RPS6KB1 protein CTD PMID:10998351 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] more ... CTD PMID:14516795 more ... N-acetyl-L-cysteine multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of RPS6KB1 protein] and Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21195169 and PMID:26804764 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Sirolimus promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:31645432 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31645432 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein] and Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]] CTD PMID:22689575 N-methyl-4-phenylpyridinium decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25017139 N-methyl-4-phenylpyridinium decreases response to substance EXP 6480464 RPS6KB1 protein modified form results in decreased susceptibility to 1-Methyl-4-phenylpyridinium CTD PMID:25680463 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 [ULK1 protein results in decreased phosphorylation of RPS6KB1 protein] which results in increased susceptibility to 1-Methyl-4-phenylpyridinium and ULK1 protein promotes the reaction [1-Methyl-4-phenylpyridinium results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:25680463 N-methyl-4-phenylpyridinium decreases phosphorylation EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25680463 N-methyl-N-nitrosourea multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of RPS6KB1 protein CTD PMID:22465879 N-nitrosodimethylamine multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Dimethylnitrosamine results in increased phosphorylation of and results in increased activity of RPS6KB1 protein CTD PMID:12971962 naringin multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 naringin inhibits the reaction [AICA ribonucleotide results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:15342961 and PMID:19810018 neomycin affects phosphorylation EXP 6480464 Neomycin affects the phosphorylation of RPS6KB1 protein CTD PMID:16537399 niclosamide decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Niclosamide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27542212 and PMID:30258081 nicotine increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Nicotine results in increased phosphorylation of RPS6KB1 protein CTD PMID:30259641 nicotine multiple interactions EXP 6480464 Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:31926917 nicotine multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:30259641 and PMID:31926917 nicotinic acid multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Niacin results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein CTD PMID:12837665 nitric oxide multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [resveratrol results in decreased activity of RPS6KB1 protein] which results in increased abundance of Nitric Oxide and [Sirolimus results in decreased activity of RPS6KB1 protein] which results in increased abundance of Nitric Oxide CTD PMID:21544240 Nodularin increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 nodularin results in increased phosphorylation of RPS6KB1 protein and nodularin results in increased phosphorylation of RPS6KB1 protein alternative form CTD PMID:25192816 Nonylphenol increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 nonylphenol results in increased expression of RPS6KB1 mRNA CTD PMID:27832966 Nonylphenol decreases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 nonylphenol results in decreased expression of RPS6KB1 mRNA CTD PMID:27832966 ochratoxin A increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 ochratoxin A results in increased phosphorylation of RPS6KB1 protein CTD PMID:31154016 okadaic acid multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 naringin inhibits the reaction [Okadaic Acid results in increased phosphorylation of RPS6KB1 protein] CTD PMID:15342961 okadaic acid increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Okadaic Acid results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342961 oligopeptide decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Oligopeptides analog results in decreased phosphorylation of RPS6KB1 protein CTD PMID:24875536 omipalisib decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 omipalisib results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21464613 and PMID:22733540 orotic acid multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Orotic Acid inhibits the reaction [STK11 protein results in decreased phosphorylation of RPS6KB1 protein] and Sirolimus inhibits the reaction [Orotic Acid results in increased phosphorylation of RPS6KB1 protein] CTD PMID:22863860 orotic acid increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Orotic Acid results in increased phosphorylation of RPS6KB1 protein CTD PMID:22863860 ouabain affects expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Ouabain affects the expression of RPS6KB1 mRNA CTD PMID:28099878 oxybenzone increases expression ISO RPS6KB1 (Homo sapiens) 6480464 oxybenzone results in increased expression of RPS6KB1 mRNA CTD PMID:36581016 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of RPS6KB1 mRNA CTD PMID:27106289 p-tert-Amylphenol increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 4-tert-octylphenol results in increased phosphorylation of RPS6KB1 protein CTD PMID:32466334 paclitaxel multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Paclitaxel co-treated with Metformin] results in decreased expression of RPS6KB1 mRNA CTD PMID:29309887 palbociclib multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 palbociclib promotes the reaction [BMS 754807 results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:24986516 paraquat decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Paraquat results in decreased phosphorylation of RPS6KB1 protein CTD PMID:20929985 Parthenin decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 parthenin analog results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25196075 Parthenin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [parthenin analog results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:25196075 PD173074 multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [PKI 166 co-treated with PD 173074] results in decreased activity of RPS6KB1 protein CTD PMID:15377668 perfluorooctanoic acid increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 perfluorooctanoic acid results in increased expression of RPS6KB1 protein CTD PMID:37236338 phenethyl isothiocyanate decreases phosphorylation EXP 6480464 phenethyl isothiocyanate results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27579538 phenethyl isothiocyanate decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 phenethyl isothiocyanate results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27579538 phenobarbital affects expression ISO RPS6KB1 (Homo sapiens) 6480464 Phenobarbital affects the expression of RPS6KB1 mRNA CTD PMID:19159669 phenylarsine oxide multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [oxophenylarsine results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:16183647 phenylarsine oxide increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 oxophenylarsine results in increased phosphorylation of RPS6KB1 protein CTD PMID:16183647 phenylephrine multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3 more ... CTD PMID:12411397 more ... phenylephrine increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Phenylephrine results in increased phosphorylation of RPS6KB1 protein CTD PMID:15757502 and PMID:15795328 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] more ... CTD PMID:10993886 phorbol 13-acetate 12-myristate multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein] and Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30696844 phorbol 13-acetate 12-myristate increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein CTD PMID:30696844 phosphatidic acid multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Phosphatidic Acids results in increased phosphorylation of and results in increased activity of RPS6KB1 protein CTD PMID:15255942 pioglitazone multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6KB1 protein] CTD PMID:26643070 pioglitazone decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 pioglitazone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:26643070 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of RPS6KB1 mRNA CTD PMID:20813756 platycodin D decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 platycodin D results in decreased expression of RPS6KB1 protein modified form CTD PMID:26078792 prazosin multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Prazosin inhibits the reaction [Phenylephrine results in increased activity of RPS6KB1 protein] CTD PMID:12720544 progesterone multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of RPS6KB1 protein CTD PMID:22465879 propranolol increases phosphorylation EXP 6480464 Propranolol results in increased phosphorylation of RPS6KB1 protein CTD PMID:16537399 propranolol multiple interactions EXP 6480464 Sirolimus inhibits the reaction [Propranolol results in increased phosphorylation of RPS6KB1 protein] CTD PMID:16537399 puerarin increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 puerarin results in increased phosphorylation of RPS6KB1 protein CTD PMID:27796870 puerarin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Sirolimus inhibits the reaction [puerarin results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27796870 puerarin multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 puerarin inhibits the reaction [lead nitrate results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27762461 pyrvinium decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 pyrvinium results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27542212 quercetin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Quercetin analog co-treated with Gold analog] results in decreased expression of RPS6KB1 protein more ... CTD PMID:20551291 more ... quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [IGF1 protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:24353828 quercetin multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [arsenite results in increased phosphorylation of RPS6KB1 protein] CTD PMID:20377179 quercetin decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Quercetin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:20551291 and PMID:23094058 quercetin decreases activity ISO RPS6KB1 (Homo sapiens) 6480464 Quercetin results in decreased activity of RPS6KB1 protein CTD PMID:10998351 rac-lactic acid decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of RPS6KB1 mRNA CTD PMID:30851411 resveratrol increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 resveratrol results in increased phosphorylation of RPS6KB1 protein CTD PMID:23680031 resveratrol decreases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 resveratrol results in decreased expression of RPS6KB1 protein modified form CTD PMID:25394677 resveratrol decreases phosphorylation EXP 6480464 resveratrol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:24304514 and PMID:26223300 resveratrol decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 resveratrol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16979140 more ... resveratrol decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 resveratrol results in decreased phosphorylation of RPS6KB1 protein CTD PMID:18562309 and PMID:24304514 resveratrol decreases activity ISO RPS6KB1 (Homo sapiens) 6480464 resveratrol results in decreased activity of RPS6KB1 protein CTD PMID:15297429 more ... resveratrol multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 [Sirolimus co-treated with resveratrol] results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:12237323 more ... resveratrol decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 resveratrol results in decreased expression of RPS6KB1 protein and resveratrol results in decreased expression of RPS6KB1 protein modified form CTD PMID:17534123 more ... resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of RPS6KB1 protein modified form CTD PMID:21224254 resveratrol multiple interactions EXP 6480464 [[resveratrol results in increased activity of SIRT1 protein] which results in decreased activity of MTOR protein] which results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:21321189 more ... resveratrol multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 more ... CTD PMID:15297429 more ... rotenone decreases phosphorylation EXP 6480464 Rotenone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:26031332 rotenone multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 [Rotenone results in increased abundance of Hydrogen Peroxide] inhibits the reaction [MTOR protein results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:25304210 rottlerin multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 rottlerin inhibits the reaction [Phenylephrine results in increased activity of RPS6KB1 protein] CTD PMID:12720544 rottlerin decreases activity ISO Rps6kb1 (Rattus norvegicus) 6480464 rottlerin results in decreased activity of RPS6KB1 protein CTD PMID:12720544 roxarsone multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Roxarsone results in increased expression of and results in increased phosphorylation of RPS6KB1 protein and Sirolimus inhibits the reaction [Roxarsone results in increased expression of and results in increased phosphorylation of RPS6KB1 protein] CTD PMID:35985552 roxarsone increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Roxarsone results in increased expression of RPS6KB1 mRNA CTD PMID:35985552 rucaparib multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Irinotecan co-treated with rucaparib] results in decreased expression of RPS6KB1 protein CTD PMID:30612311 Salidroside multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]] and rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:24989011 SB 203580 multiple interactions EXP 6480464 SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] and Sodium Salicylate inhibits the reaction [SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]] CTD PMID:10993886 SB 415286 multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 and 5-dione inhibits the reaction [resveratrol results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:23292070 serpentine asbestos decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Asbestos and Serpentine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:24735948 sertraline multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Sertraline results in increased phosphorylation of and results in increased activity of RPS6KB1 protein and Sirolimus inhibits the reaction [Sertraline results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:17728140 sertraline decreases phosphorylation EXP 6480464 Sertraline results in decreased phosphorylation of RPS6KB1 protein CTD PMID:33124469 sertraline multiple interactions EXP 6480464 VDAC1 protein affects the reaction [Sertraline results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:33124469 sertraline decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Sertraline results in decreased phosphorylation of RPS6KB1 protein CTD PMID:33124469 Shikonin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 shikonin promotes the reaction [Oxygen deficiency results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:28684144 silicon dioxide decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Silicon Dioxide analog results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27613482 simvastatin decreases phosphorylation EXP 6480464 Simvastatin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27734117 and PMID:33034787 simvastatin multiple interactions EXP 6480464 FST protein inhibits the reaction [Simvastatin results in decreased phosphorylation of RPS6KB1 protein] and IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:27734117 and PMID:33034787 sirolimus multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Dexamethasone co-treated with Sirolimus] inhibits the reaction [IGF1 protein results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:15070696 more ... sirolimus increases expression EXP 6480464 Sirolimus results in increased expression of RPS6KB1 protein modified form CTD PMID:25884947 sirolimus increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Sirolimus results in increased phosphorylation of RPS6KB1 protein CTD PMID:24304514 sirolimus decreases phosphorylation EXP 6480464 Sirolimus results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16537399 more ... sirolimus decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Sirolimus results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16391472 and PMID:24304514 sirolimus decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Sirolimus results in decreased expression of RPS6KB1 protein modified form CTD PMID:23255002 more ... sirolimus decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Sirolimus results in decreased phosphorylation of RPS6KB1 protein and Sirolimus results in decreased phosphorylation of S6K protein CTD PMID:15070696 more ... sirolimus decreases activity EXP 6480464 Sirolimus results in decreased activity of RPS6KB1 protein CTD PMID:19246562 sirolimus multiple interactions EXP 6480464 [[manganese chloride results in increased abundance of Manganese] which co-treated with Sirolimus] results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:14516795 more ... sirolimus decreases activity ISO RPS6KB1 (Homo sapiens) 6480464 [Sirolimus results in decreased activity of MTOR protein] which results in decreased activity of RPS6KB1 protein and Sirolimus results in decreased activity of RPS6KB1 protein CTD PMID:14673156 more ... sirolimus multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 [Sirolimus co-treated with Resveratrol] results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:12411397 more ... sodium arsenite multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of RPS6KB1 protein more ... CTD PMID:22869613 more ... sodium arsenite increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 sodium arsenite results in increased phosphorylation of RPS6KB1 protein CTD PMID:26432159 sodium arsenite increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 sodium arsenite results in increased phosphorylation of RPS6KB1 protein CTD PMID:26432159 and PMID:33781819 sodium arsenite decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 sodium arsenite results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22869613 sodium fluoride decreases phosphorylation EXP 6480464 Sodium Fluoride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34536393 sodium fluoride multiple interactions EXP 6480464 4 more ... CTD PMID:34536393 sodium fluoride decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 Sodium Fluoride results in decreased phosphorylation of RPS6KB1 protein CTD PMID:34536393 sodium fluoride decreases expression EXP 6480464 Sodium Fluoride results in decreased expression of RPS6KB1 mRNA CTD PMID:34536393 Sodium salicylate multiple interactions EXP 6480464 Sodium Salicylate inhibits the reaction [SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]] more ... CTD PMID:10993886 sorafenib multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 arsenic trioxide inhibits the reaction [sorafenib results in increased phosphorylation of RPS6KB1 protein] CTD PMID:25416439 sorafenib decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Sorafenib results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21858812 sorafenib increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 sorafenib results in increased phosphorylation of RPS6KB1 protein CTD PMID:25416439 stilbenoid decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Stilbenes results in decreased phosphorylation of RPS6KB1 protein CTD PMID:23059970 succimer multiple interactions EXP 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of RPS6KB1 mRNA CTD PMID:21641980 sulfates affects methylation ISO RPS6KB1 (Homo sapiens) 6480464 Sulfates affects the methylation of RPS6KB1 promoter CTD PMID:25395096 sulfates multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Soot co-treated with Sulfates] affects the methylation of RPS6KB1 promoter CTD PMID:25395096 sunitinib increases expression ISO RPS6KB1 (Homo sapiens) 6480464 Sunitinib results in increased expression of RPS6KB1 mRNA CTD PMID:31533062 superoxide multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [resveratrol results in decreased activity of RPS6KB1 protein] which results in decreased abundance of Superoxides and [Sirolimus results in decreased activity of RPS6KB1 protein] which results in decreased abundance of Superoxides CTD PMID:21544240 swainsonine decreases phosphorylation EXP 6480464 Swainsonine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:36402259 tamibarotene affects expression ISO RPS6KB1 (Homo sapiens) 6480464 tamibarotene affects the expression of RPS6KB1 mRNA CTD PMID:15498508 tamoxifen multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [Tamoxifen results in decreased activity of MTOR protein] which results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19931998 tamoxifen increases activity ISO RPS6KB1 (Homo sapiens) 6480464 [Tamoxifen results in increased activity of AKT1 protein] which results in increased activity of RPS6KB1 protein CTD PMID:20372086 tamoxifen decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Tamoxifen results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19931998 Tautomycin increases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 tautomycin results in increased phosphorylation of RPS6KB1 protein CTD PMID:15342961 Temsirolimus multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 temsirolimus promotes the reaction [2-(4-hydroxyphenyl)-3-methyl-1-(4-(2-piperidin-1-yl-ethoxy)-benzyl)-1H-indol-5-ol results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:16954435 Temsirolimus multiple interactions EXP 6480464 temsirolimus inhibits the reaction [Dronabinol results in increased phosphorylation of RPS6KB1 protein] CTD PMID:32773031 Temsirolimus decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 temsirolimus results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16033649 and PMID:16954435 teriflunomide decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 teriflunomide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:19174558 testosterone multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [bicalutamide co-treated with Testosterone] results in decreased phosphorylation of RPS6KB1 protein more ... CTD PMID:21036700 testosterone increases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Testosterone results in increased phosphorylation of RPS6KB1 protein CTD PMID:21036700 testosterone decreases phosphorylation EXP 6480464 Testosterone deficiency results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21045173 testosterone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Testosterone deficiency results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:21045173 testosterone increases activity ISO RPS6KB1 (Homo sapiens) 6480464 [Testosterone results in increased activity of RAF1 protein] which results in increased activity of RPS6KB1 protein CTD PMID:20372086 tetrathiomolybdate(2-) decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 tetrathiomolybdate results in decreased phosphorylation of RPS6KB1 protein CTD PMID:37290678 theobromine multiple interactions ISO Rps6kb1 (Rattus norvegicus) 127229954 [Theobromine co-treated with Theanine] inhibits the reaction [1 more ... RGD thioacetamide increases phosphorylation EXP 6480464 Thioacetamide results in increased phosphorylation of RPS6KB1 protein CTD PMID:27363783 thioacetamide multiple interactions EXP 6480464 cucurbitacin E inhibits the reaction [Thioacetamide results in increased phosphorylation of RPS6KB1 protein] and Curcumin inhibits the reaction [Thioacetamide results in increased phosphorylation of RPS6KB1 protein] CTD PMID:27363783 Thiorphan decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 Thiorphan results in decreased phosphorylation of RPS6KB1 protein CTD PMID:31054283 torin 1 decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1 and 6)naphthyridin-2(1H)-one results in decreased phosphorylation of RPS6KB1 protein CTD PMID:21858812 more ... torin 1 decreases phosphorylation EXP 6480464 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1 and 6)naphthyridin-2(1H)-one results in decreased phosphorylation of RPS6KB1 protein CTD PMID:29945972 trametinib decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 trametinib results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22733540 Tributyltin oxide decreases phosphorylation EXP 6480464 bis(tri-n-butyltin)oxide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:22174045 Tributyltin oxide multiple interactions EXP 6480464 bis(tri-n-butyltin)oxide results in decreased expression of and results in decreased phosphorylation of RPS6KB1 protein CTD PMID:24375594 trichloroethene increases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of RPS6KB1 mRNA CTD PMID:19448997 trichloroethene decreases expression ISO Rps6kb1 (Rattus norvegicus) 6480464 Trichloroethylene results in decreased expression of RPS6KB1 mRNA CTD PMID:33387578 trichostatin A multiple interactions EXP 6480464 trichostatin A promotes the reaction [Cisplatin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:29476062 trichostatin A multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 trichostatin A promotes the reaction [Cisplatin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:29476062 trichostatin A decreases phosphorylation ISO Rps6kb1 (Rattus norvegicus) 6480464 trichostatin A results in decreased phosphorylation of RPS6KB1 protein CTD PMID:29476062 trifluoperazine multiple interactions EXP 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21544200 trifluoperazine multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21544200 troglitazone multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 troglitazone results in decreased activity of and results in decreased phosphorylation of RPS6KB1 protein CTD PMID:16825603 trovafloxacin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 [trovafloxacin co-treated with TNF protein] results in increased phosphorylation of RPS6KB1 protein CTD PMID:33609687 tunicamycin increases expression EXP 6480464 Tunicamycin results in increased expression of RPS6KB1 mRNA CTD PMID:17127020 tunicamycin multiple interactions EXP 6480464 Tunicamycin inhibits the reaction [[EIF2AK4 gene mutant form affects the susceptibility to Amino Acids deficiency] which results in increased phosphorylation of RPS6KB1 protein] CTD PMID:29449374 ursolic acid decreases expression ISO RPS6KB1 (Homo sapiens) 6480464 Ursolic Acid results in decreased expression of RPS6KB1 protein CTD PMID:24802810 usnic acid decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 usnic acid results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25078063 valproic acid increases expression ISO RPS6KB1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of RPS6KB1 mRNA CTD PMID:29154799 vanadium atom multiple interactions EXP 6480464 PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] and Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein CTD PMID:14971662 vanadium(0) multiple interactions EXP 6480464 PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] and Vanadium results in increased phosphorylation of and results in increased activity of RPS6KB1 protein CTD PMID:14971662 warfarin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 epigallocatechin gallate promotes the reaction [Warfarin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of RPS6KB1 protein]] and Warfarin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of RPS6KB1 protein] CTD PMID:36162953 wortmannin multiple interactions EXP 6480464 wortmannin inhibits the reaction [arsenite affects the activity of RPS6KB1 protein] CTD PMID:14516795 wortmannin multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 Wortmannin inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased phosphorylation of RPS6KB1 protein] and Wortmannin inhibits the reaction [INS protein results in increased expression of RPS6KB1 protein modified form] CTD PMID:20936651 and PMID:32802178 wortmannin multiple interactions ISO Rps6kb1 (Rattus norvegicus) 6480464 wortmannin inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21195169 wortmannin decreases phosphorylation ISO RPS6KB1 (Homo sapiens) 6480464 wortmannin results in decreased phosphorylation of RPS6KB1 protein CTD PMID:25663935 zearalenone multiple interactions EXP 6480464 2-aminoethyl diphenylborinate inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein] more ... CTD PMID:30394307 and PMID:31982503 zearalenone decreases phosphorylation EXP 6480464 Zearalenone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:30394307 and PMID:31982503 zotarolimus multiple interactions ISO RPS6KB1 (Homo sapiens) 6480464 zotarolimus inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein] CTD PMID:19567381
