Gene: Scn10a (sodium channel, voltage-gated, type X, alpha) Mus musculus
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Symbol: Scn10a
Name: sodium channel, voltage-gated, type X, alpha
Description: ENCODES a protein that exhibits voltage-gated sodium channel activity; ion channel binding (ortholog); INVOLVED IN cardiac conduction; regulation of atrial cardiac muscle cell membrane depolarization; sodium ion transport; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH abnormal action potential; abnormal behavioral response to addictive substance; abnormal brain wave pattern; ASSOCIATED WITH Atrial Fibrillation (ortholog); atrial fibrillation (ortholog); Brugada Syndrome (ortholog); FOUND IN axon; C-fiber; plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; capsaicin
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Nav1.8; peripheral nerve sodium channel 3; PN3; sensory neuron sodium channel; SNS; sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; voltage gated sodium channel; voltage-gated sodium channel Nav1.8 variant a; voltage-gated sodium channel Nav1.8 variant b; voltage-gated sodium channel subunit alpha Nav1.8
Orthologs:
Homo sapiens (human) : SCN10A (sodium voltage-gated channel alpha subunit 10)  HGNC
Rattus norvegicus (Norway rat) : Scn10a (sodium voltage-gated channel alpha subunit 10)
Chinchilla lanigera (long-tailed chinchilla) : Scn10a (sodium voltage-gated channel alpha subunit 10)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN10A (sodium voltage-gated channel alpha subunit 10)
Canis lupus familiaris (dog) : SCN10A (sodium voltage-gated channel alpha subunit 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn10a (sodium voltage-gated channel alpha subunit 10)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389119,608,456 - 119,719,322 (-)NCBIGRCm38mm10GRCm38
MGSCv379119,517,584 - 119,603,478 (-)NCBIGRCm37mm9NCBIm37
MGSCv369119,457,165 - 119,543,058 (-)NCBImm8
Celera9120,082,157 - 120,189,198 (-)NCBI
Cytogenetic Map9 F3NCBImapview
cM Map971.33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Scn10a
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
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Vista + UCSC

RGD Object Information
RGD ID: 736179
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2017-09-05
Status: ACTIVE