Gene: Cflar (CASP8 and FADD-like apoptosis regulator)  Mus musculus
Symbol: Cflar
Name: CASP8 and FADD-like apoptosis regulator
Description: ENCODES a protein that exhibits enzyme activator activity (ortholog); protease binding (ortholog); INVOLVED IN negative regulation of apoptotic process; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of extrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN FasL mediated signaling pathway; Trail mediated signaling pathway; apoptotic cell death pathway; ASSOCIATED WITH abnormal abdominal lymph node morphology; abnormal B cell number; abnormal bone marrow cell number; FOUND IN cytoplasm; CD95 death-inducing signaling complex (ortholog); death-inducing signaling complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-galactopyranose; 3,4-methylenedioxymethamphetamine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310024N18Rik; A430105C05Rik; AI646576; AU021929; c-Flip; Cash; CASP8 and FADD-like apoptosis regulator; caspase homolog; caspase-eight-related protein; caspase-like apoptosis regulatory protein; Casper; cellular FLICE-like inhibitory protein; CLARP; ENSMUSG00000050533; ENSMUSG00000072980; FADD-like antiapoptotic molecule 1; FLAME; FLAME-1; FLAME-1; Flip; Gm9845; I-FLICE; inhibitor of FLICE; MACH-related inducer of toxicity; MGC103395; MRIT; OTTMUSP00000021141; OTTMUSP00000021142; OTTMUSP00000021143; OTTMUSP00000021144; usurpin
Orthologs: Homo sapiens : CFLAR (CASP8 and FADD-like apoptosis regulator)  HGNC
Rattus norvegicus : Cflar (CASP8 and FADD-like apoptosis regulator)
Related Pseudogenes: Gm9845  
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm38158,713,286 - 58,758,884+NCBI
Mouse cM Map129.16 NCBI
Mouse Celera Assembly159,232,248 - 59,277,933+NCBI
Mouse Genome Assembly Build 37158,770,130 - 58,815,728+NCBI
Mouse Genome Assembly Build 36.1158,770,130 - 58,815,728+NCBI
Mouse Cytogenetic Map1 C1.3 NCBI
Model

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Sequence

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RGD Object Information
RGD ID: 731977
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2013-05-28
Status: ACTIVE



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