Pink1 (PTEN induced putative kinase 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Pink1 (PTEN induced putative kinase 1) Mus musculus
Analyze
Symbol: Pink1
Name: PTEN induced putative kinase 1
RGD ID: 1314002
MGI Page MGI
Description: Enables ion binding activity and protein kinase activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of protein metabolic process; and protein stabilization. Acts upstream of or within positive regulation of dopamine secretion; positive regulation of dopaminergic synaptic transmission; and positive regulation of mitochondrial electron transport, NADH to ubiquinone. Located in endoplasmic reticulum and mitochondrial inner membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Used to study Parkinson's disease 6. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 6. Orthologous to human PINK1 (PTEN induced kinase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1190006F07Rik; AU042772; AW557854; br; BRPK; mFLJ00387; PTEN-induced putative kinase protein 1; serine/threonine-protein kinase PINK1, mitochondrial
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394138,040,718 - 138,053,631 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4138,040,720 - 138,053,618 (-)EnsemblGRCm39 Ensembl
GRCm384138,313,409 - 138,326,296 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4138,313,409 - 138,326,307 (-)EnsemblGRCm38mm10GRCm38
MGSCv374137,869,324 - 137,882,211 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364137,585,488 - 137,598,347 (-)NCBIMGSCv36mm8
Celera4140,093,554 - 140,110,379 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(R)-lipoic acid  (EXP)
1,1-dichloroethene  (EXP)
1,3-dichloropropan-2-ol  (ISO)
1,4-benzoquinone  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,5,6,7-TETRABROMOBENZOTRIAZOLE  (ISO)
4-nitrophenol  (EXP)
4-phenylbutyric acid  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetaldehyde  (ISO)
acetamide  (ISO)
acetylcholine  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
aluminium atom  (EXP)
aluminium(0)  (EXP)
amitrole  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
aristolochic acids  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bupivacaine  (EXP)
buspirone  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (EXP)
carnosic acid  (ISO)
CCCP  (EXP,ISO)
chloroquine  (EXP)
chlorpyrifos  (EXP,ISO)
chromium(6+)  (EXP,ISO)
cisplatin  (ISO)
clofibric acid  (ISO)
clotrimazole  (ISO)
coenzyme Q10  (EXP)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
curcumin  (ISO)
cyclosporin A  (EXP,ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (EXP)
deguelin  (ISO)
desferrioxamine B  (ISO)
Di-n-octyl phthalate  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dioxygen  (EXP,ISO)
dithionite(2-)  (ISO)
dopamine  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fenpyroximate  (ISO)
fenvalerate  (ISO)
fructose  (EXP)
furosemide  (ISO)
Fusaric acid  (ISO)
Genipin  (EXP)
glafenine  (ISO)
glucose  (ISO)
hexadecanoic acid  (ISO)
Honokiol  (ISO)
hydrogen peroxide  (EXP,ISO)
inositol  (ISO)
iodixanol  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lipoic acid  (EXP)
lycopene  (EXP)
manganese(II) chloride  (ISO)
melatonin  (EXP,ISO)
methimazole  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-acetylsphingosine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (ISO)
nickel atom  (EXP)
nickel dichloride  (EXP)
O-acetyl-L-carnitine  (EXP)
ochratoxin A  (ISO)
oleanolic acid  (ISO)
oleic acid  (ISO)
oligomycin A  (ISO)
Ophiopogonin D  (ISO)
oxidopamine  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
phlorizin  (EXP)
phytosphingosine  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
poly(vinylpyrrolidone)  (EXP)
ponasterone A  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
pyrimidifen  (ISO)
rac-lactic acid  (ISO)
reactive oxygen species  (EXP,ISO)
remifentanil  (ISO)
Repaglinide  (ISO)
resveratrol  (EXP,ISO)
rotenone  (EXP,ISO)
silibinin  (ISO)
silicon dioxide  (EXP,ISO)
silver(1+) nitrate  (EXP)
sirolimus  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
sorafenib  (EXP,ISO)
streptozocin  (EXP)
succimer  (ISO)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
superoxide  (EXP)
T-2 toxin  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (EXP)
taurine  (ISO)
tebufenpyrad  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thifluzamide  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
toyocamycin  (EXP)
tricalcium bis(phosphate)  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
trifloxystrobin  (ISO)
trifluoperazine  (ISO)
trovafloxacin  (ISO)
tunicamycin  (EXP,ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
autophagy  (IEA)
catecholamine secretion  (IMP)
cellular response to hydrogen sulfide  (ISO)
cellular response to hypoxia  (IMP,ISO)
cellular response to oxidative stress  (IMP,ISO)
cellular response to toxic substance  (IMP)
dopamine secretion  (IMP)
establishment of localization in cell  (IMP)
establishment of protein localization to mitochondrion  (ISO)
hemopoiesis  (ISO)
intracellular signal transduction  (IDA,ISO)
maintenance of protein location in mitochondrion  (ISO)
mitochondrial fission  (ISO)
mitochondrion organization  (ISO)
mitochondrion to lysosome vesicle-mediated transport  (ISO)
mitophagy  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of autophagosome assembly  (ISO)
negative regulation of cellular process  (ISO)
negative regulation of fatty acid beta-oxidation  (ISO)
negative regulation of gene expression  (IMP,ISO)
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway  (ISO)
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway  (IMP)
negative regulation of intrinsic apoptotic signaling pathway  (ISO)
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide  (ISO)
negative regulation of macroautophagy  (ISO)
negative regulation of mitochondrial fission  (ISO)
negative regulation of mitophagy  (ISO)
negative regulation of neuron apoptotic process  (IMP,ISO)
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway  (ISO)
negative regulation of reactive oxygen species metabolic process  (ISO)
positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization  (ISO)
positive regulation of canonical NF-kappaB signal transduction  (ISO)
positive regulation of catecholamine secretion  (IMP)
positive regulation of cristae formation  (ISO)
positive regulation of dopamine secretion  (IMP)
positive regulation of macroautophagy  (ISO)
positive regulation of mitochondrial electron transport, NADH to ubiquinone  (IMP)
positive regulation of mitochondrial fission  (IBA,ISO)
positive regulation of mitophagy in response to mitochondrial depolarization  (ISO)
positive regulation of NMDA glutamate receptor activity  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of protein dephosphorylation  (IMP)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein targeting to mitochondrion  (ISO)
positive regulation of release of cytochrome c from mitochondria  (ISO)
positive regulation of synaptic transmission, dopaminergic  (IMP)
positive regulation of translation  (IMP)
protein stabilization  (IMP,ISO)
protein ubiquitination  (ISO)
regulation of apoptotic process  (IBA)
regulation of cellular response to oxidative stress  (ISO)
regulation of hydrogen peroxide metabolic process  (IMP)
regulation of mitochondrial membrane potential  (ISO)
regulation of mitochondrion organization  (ISO)
regulation of neuron apoptotic process  (IMP)
regulation of oxidative phosphorylation  (ISO)
regulation of protein targeting to mitochondrion  (ISO)
regulation of protein ubiquitination  (ISO)
regulation of protein-containing complex assembly  (ISO)
regulation of reactive oxygen species metabolic process  (ISO)
respiratory electron transport chain  (IMP)
response to ischemia  (ISO)
response to oxidative stress  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cell physiology  (IAGP)
abnormal cellular respiration  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal dopaminergic neuron morphology  (IAGP)
abnormal gait  (IAGP)
abnormal innervation  (IAGP)
abnormal locomotor behavior  (IAGP)
abnormal lysosome morphology  (IAGP)
abnormal mitochondrial ATP synthesis coupled electron transport  (IAGP)
abnormal mitochondrial morphology  (IAGP)
abnormal mitochondrial physiology  (IAGP)
abnormal motor neuron morphology  (IAGP)
abnormal nervous system electrophysiology  (IAGP)
abnormal nervous system physiology  (IAGP)
abnormal neurite morphology  (IAGP)
abnormal neuron physiology  (IAGP)
abnormal nucleolus morphology  (IAGP)
abnormal olfaction  (IAGP)
abnormal olfactory bulb glomerular layer morphology  (IAGP)
abnormal respiratory electron transport chain  (IAGP)
abnormal sensory capabilities/reflexes/nociception  (IAGP)
abnormal social investigation  (IAGP)
alpha-synuclein inclusion body  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral content  (IEA)
decreased bone mineral density  (IEA)
decreased dopamine level  (IAGP)
decreased locomotor activity  (IAGP)
decreased mean platelet volume  (IEA)
decreased stereotypic behavior  (IAGP)
decreased vertical activity  (IAGP)
extended life span  (IAGP)
hindlimb paralysis  (IAGP)
increased interleukin-1 beta secretion  (IAGP)
increased interleukin-10 secretion  (IAGP)
increased interleukin-12 secretion  (IAGP)
increased neuron apoptosis  (IAGP)
increased sensitivity to induced cell death  (IAGP)
kyphosis  (IAGP)
neurodegeneration  (IAGP)
neuron degeneration  (IAGP)
neuronal cytoplasmic inclusions  (IAGP)
oxidative stress  (IAGP)
paresis  (IAGP)
premature death  (IAGP)
reduced long-term depression  (IAGP)
reduced long-term potentiation  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Genes associated with Parkinson's disease: regulation of autophagy and beyond. Beilina A and Cookson MR, J Neurochem. 2015 Jul 30. doi: 10.1111/jnc.13266.
2. Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease. Dave KD, etal., Neurobiol Dis. 2014 Oct;70:190-203. doi: 10.1016/j.nbd.2014.06.009. Epub 2014 Jun 24.
3. The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications. Durcan TM and Fon EA, Genes Dev. 2015 May 15;29(10):989-99. doi: 10.1101/gad.262758.115.
4. PINK1 protein in normal human brain and Parkinson's disease. Gandhi S, etal., Brain. 2006 Jul;129(Pt 7):1720-31. Epub 2006 May 15.
5. Impaired intracellular trafficking defines early Parkinson's disease. Hunn BH, etal., Trends Neurosci. 2015 Mar;38(3):178-88. doi: 10.1016/j.tins.2014.12.009. Epub 2015 Jan 29.
6. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
7. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
8. Mitochondria and mitophagy: the yin and yang of cell death control. Kubli DA and Gustafsson AB, Circ Res. 2012 Oct 12;111(9):1208-21. doi: 10.1161/CIRCRESAHA.112.265819.
9. MGDs mouse GO annotations MGD data from the GO Consortium
10. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
11. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. Mouse MP Annotation Import Pipeline RGD automated import pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Parkin and PINK1: much more than mitophagy. Scarffe LA, etal., Trends Neurosci. 2014 Jun;37(6):315-24. doi: 10.1016/j.tins.2014.03.004. Epub 2014 Apr 13.
17. Regulation of dopamine presynaptic markers and receptors in the striatum of DJ-1 and Pink1 knockout rats. Sun J, etal., Neurosci Lett. 2013 Dec 17;557 Pt B:123-8. doi: 10.1016/j.neulet.2013.10.034. Epub 2013 Oct 22.
18. Early Expression of Parkinson's Disease-Related Mitochondrial Abnormalities in PINK1 Knockout Rats. Villeneuve LM, etal., Mol Neurobiol. 2016 Jan;53(1):171-86. doi: 10.1007/s12035-014-8927-y. Epub 2014 Nov 25.
19. Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses. Wei H, etal., Biochim Biophys Acta. 2015 Oct;1853(10 Pt B):2784-90. doi: 10.1016/j.bbamcr.2015.03.013. Epub 2015 Apr 1.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11494141   PMID:12477932   PMID:14607334   PMID:14681479   PMID:14697668   PMID:15489334   PMID:15782199  
PMID:16141072   PMID:16141073   PMID:16771836   PMID:17389931   PMID:17563363   PMID:17950257   PMID:18218782   PMID:18560593   PMID:18614015   PMID:18687899   PMID:18687901   PMID:19071114  
PMID:19167501   PMID:19229105   PMID:19276113   PMID:19285945   PMID:19492057   PMID:19546216   PMID:19786829   PMID:19909785   PMID:20049710   PMID:20068297   PMID:20153330   PMID:20404107  
PMID:20817094   PMID:20926611   PMID:20940149   PMID:21126574   PMID:21173115   PMID:21195752   PMID:21249202   PMID:21262209   PMID:21267068   PMID:21385841   PMID:21421046   PMID:21555650  
PMID:21601636   PMID:21606348   PMID:21637291   PMID:21664494   PMID:21672589   PMID:21677750   PMID:21839811   PMID:21873635   PMID:21945539   PMID:22028146   PMID:22043175   PMID:22223879  
PMID:22265660   PMID:22511790   PMID:22630785   PMID:22872702   PMID:23144451   PMID:23165879   PMID:23238720   PMID:23256036   PMID:23295771   PMID:23303188   PMID:23341629   PMID:23348839  
PMID:23440919   PMID:23449626   PMID:23472196   PMID:23620051   PMID:23638067   PMID:23688429   PMID:23751051   PMID:23754282   PMID:24037540   PMID:24128678   PMID:24151868   PMID:24167038  
PMID:24194600   PMID:24475098   PMID:24487387   PMID:24553947   PMID:24615332   PMID:24652937   PMID:24703837   PMID:24733019   PMID:24778451   PMID:24784582   PMID:24792327   PMID:24806840  
PMID:25037286   PMID:25058378   PMID:25083992   PMID:25092611   PMID:25154397   PMID:25215947   PMID:25217637   PMID:25222142   PMID:25284222   PMID:25296918   PMID:25305081   PMID:25336644  
PMID:25562319   PMID:25565208   PMID:25609609   PMID:25611391   PMID:25612572   PMID:25626353   PMID:25670069   PMID:25716315   PMID:25785991   PMID:25987559   PMID:26110811   PMID:26161534  
PMID:26184432   PMID:26203141   PMID:26440884   PMID:26498506   PMID:26538564   PMID:26746235   PMID:26850695   PMID:26975827   PMID:27034888   PMID:27345367   PMID:27445695   PMID:27528605  
PMID:27597528   PMID:27626380   PMID:27742469   PMID:27754761   PMID:27852436   PMID:28122242   PMID:28137779   PMID:28148912   PMID:28325755   PMID:28360124   PMID:28408307   PMID:28556983  
PMID:28768533   PMID:28890682   PMID:28933786   PMID:29036556   PMID:29077793   PMID:29123128   PMID:29166608   PMID:29172924   PMID:29196503   PMID:29229503   PMID:29234155   PMID:29242192  
PMID:29242539   PMID:29287722   PMID:29321620   PMID:29337137   PMID:29352272   PMID:29363258   PMID:29458150   PMID:29501495   PMID:29665074   PMID:29689442   PMID:29844467   PMID:30100261  
PMID:30135585   PMID:30258205   PMID:30305733   PMID:30349076   PMID:30385753   PMID:30411223   PMID:30449314   PMID:30484658   PMID:30504091   PMID:30558471   PMID:30578322   PMID:30734931  
PMID:30735759   PMID:30863359   PMID:31139191   PMID:31170232   PMID:31207045   PMID:31229841   PMID:31277379   PMID:31316206   PMID:31336695   PMID:31339428   PMID:31486971   PMID:31489182  
PMID:31536960   PMID:31540955   PMID:31639106   PMID:31655049   PMID:31684073   PMID:31727366   PMID:31825802   PMID:31889458   PMID:32080200   PMID:32139798   PMID:32154065   PMID:32195921  
PMID:32209025   PMID:32351292   PMID:32400277   PMID:32484300   PMID:32493843   PMID:32929177   PMID:32936696   PMID:32941882   PMID:32947010   PMID:33023155   PMID:33137712   PMID:33291077  
PMID:33299968   PMID:33571581   PMID:33577398   PMID:33591165   PMID:33636335   PMID:33851544   PMID:33931895   PMID:33974284   PMID:34014489   PMID:34030589   PMID:34046942   PMID:34152608  
PMID:34288093   PMID:34328407   PMID:34576157   PMID:34614419   PMID:34655600   PMID:34706234   PMID:34823575   PMID:34924126   PMID:35129770   PMID:35248828   PMID:35422062   PMID:35436629  
PMID:35628458   PMID:35646911   PMID:35695893   PMID:35962179   PMID:35974013   PMID:36113482   PMID:36181536   PMID:36351375   PMID:36414008   PMID:36466826   PMID:36647427   PMID:36750550  
PMID:36754021   PMID:36791501   PMID:36804394   PMID:36809929   PMID:36992582   PMID:37183600   PMID:37259617   PMID:37278995   PMID:37331031   PMID:37458434   PMID:37505079   PMID:37574181  
PMID:37717824   PMID:37860954   PMID:37928264   PMID:37940999   PMID:38013600   PMID:38050606   PMID:38181706   PMID:38251428   PMID:38266580   PMID:38504131  


Genomics

Comparative Map Data
Pink1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394138,040,718 - 138,053,631 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4138,040,720 - 138,053,618 (-)EnsemblGRCm39 Ensembl
GRCm384138,313,409 - 138,326,296 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4138,313,409 - 138,326,307 (-)EnsemblGRCm38mm10GRCm38
MGSCv374137,869,324 - 137,882,211 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364137,585,488 - 137,598,347 (-)NCBIMGSCv36mm8
Celera4140,093,554 - 140,110,379 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.14NCBI
PINK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38120,633,458 - 20,651,511 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl120,633,458 - 20,651,511 (+)EnsemblGRCh38hg38GRCh38
GRCh37120,959,951 - 20,978,004 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36120,832,535 - 20,850,591 (+)NCBINCBI36Build 36hg18NCBI36
Build 34120,705,253 - 20,723,309NCBI
Celera119,284,119 - 19,302,182 (+)NCBICelera
Cytogenetic Map1p36.12NCBI
HuRef119,206,074 - 19,224,136 (+)NCBIHuRef
CHM1_1121,070,747 - 21,088,823 (+)NCBICHM1_1
T2T-CHM13v2.0120,459,649 - 20,477,706 (+)NCBIT2T-CHM13v2.0
Pink1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85155,813,838 - 155,825,950 (-)NCBIGRCr8
mRatBN7.25150,530,523 - 150,542,635 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5150,530,523 - 150,542,635 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5153,226,264 - 153,238,265 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05155,000,550 - 155,012,551 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05154,982,571 - 154,994,572 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05156,677,146 - 156,689,258 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5156,677,146 - 156,689,415 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05160,425,715 - 160,437,827 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45157,091,181 - 157,103,293 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15157,100,712 - 157,113,336 (-)NCBI
Celera5148,924,018 - 148,936,130 (-)NCBICelera
Cytogenetic Map5q36NCBI
Pink1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554521,171,205 - 1,185,125 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554521,171,115 - 1,186,338 (+)NCBIChiLan1.0ChiLan1.0
PINK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21206,472,787 - 206,490,710 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11205,585,116 - 205,603,037 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0119,583,330 - 19,601,248 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1120,627,364 - 20,646,377 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl120,627,693 - 20,645,560 (+)Ensemblpanpan1.1panPan2
PINK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1278,276,091 - 78,293,761 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl278,277,077 - 78,294,123 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha274,790,397 - 74,808,514 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0278,842,969 - 78,861,096 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl278,842,996 - 78,861,044 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1275,661,680 - 75,679,782 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0276,673,498 - 76,691,638 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0277,677,116 - 77,695,256 (-)NCBIUU_Cfam_GSD_1.0
Pink1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505840,749,706 - 40,764,701 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364746,573,623 - 6,589,478 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364746,574,471 - 6,589,478 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PINK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl678,863,190 - 78,884,640 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1678,863,195 - 78,884,663 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2673,117,387 - 73,128,340 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PINK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120111,902,135 - 111,919,082 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20111,902,765 - 111,919,069 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660334,316,686 - 4,333,643 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pink1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247645,656,229 - 5,671,260 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247645,656,207 - 5,671,260 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pink1
535 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:557
Count of miRNA genes:275
Interacting mature miRNAs:301
Transcripts:ENSMUST00000030536, ENSMUST00000105816, ENSMUST00000105817
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124055093141572792Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124055093142438020Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124264957142230960Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
4141154Nba1_mNew Zealand Black autoimmunity 1 (mouse)Not determined131650724140879275Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133676733156860686Mouse
1301108Scon2_msucrose consumption 2 (mouse)Not determined4134654451156860686Mouse
1300537Ap3q_malcohol preference 3 QTL (mouse)Not determined4134654451156860686Mouse
12050091Shm2_msperm head morphology 2 (mouse)4136876000138342753Mouse
1357534Cinda3_mcytokine induced activation 3 (mouse)Not determined4137617848142289472Mouse
1300553Athsq1_matherosclerosis susceptibility QTL 1 (mouse)Not determined4137617848151654550Mouse
4141184Tb2r1_mTGF-beta2 responsiveness 1 (mouse)Not determined137674005150676858Mouse

Markers in Region
AW557854  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384138,313,910 - 138,314,021UniSTSGRCm38
MGSCv374137,869,825 - 137,869,936UniSTSGRCm37
Celera4140,094,055 - 140,094,166UniSTS
Cytogenetic Map4D3UniSTS
Whitehead/MRC_RH41812.2UniSTS
AU042772  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384138,313,550 - 138,313,786UniSTSGRCm38
MGSCv374137,869,465 - 137,869,701UniSTSGRCm37
Celera4140,093,695 - 140,093,931UniSTS
Cytogenetic Map4D3UniSTS
Whitehead/MRC_RH41814.19UniSTS
Pink1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D3UniSTS
cM Map4 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_026880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB053476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF316872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL807249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC044743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC067066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX238874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000030536   ⟹   ENSMUSP00000030536
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4138,040,723 - 138,053,618 (-)Ensembl
GRCm38.p6 Ensembl4138,313,412 - 138,326,307 (-)Ensembl
RefSeq Acc Id: ENSMUST00000105816   ⟹   ENSMUSP00000101442
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4138,040,720 - 138,043,737 (-)Ensembl
GRCm38.p6 Ensembl4138,313,409 - 138,316,426 (-)Ensembl
RefSeq Acc Id: ENSMUST00000105817   ⟹   ENSMUSP00000101443
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4138,041,230 - 138,053,551 (-)Ensembl
GRCm38.p6 Ensembl4138,313,919 - 138,326,240 (-)Ensembl
RefSeq Acc Id: NM_026880   ⟹   NP_081156
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394138,040,720 - 138,053,607 (-)NCBI
GRCm384138,313,409 - 138,326,296 (-)ENTREZGENE
MGSCv374137,869,324 - 137,882,211 (-)RGD
Celera4140,093,554 - 140,110,379 (-)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036164400   ⟹   XP_036020293
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394138,040,718 - 138,053,631 (-)NCBI
Sequence:
RefSeq Acc Id: NP_081156   ⟸   NM_026880
- Peptide Label: precursor
- UniProtKB: Q811I8 (UniProtKB/Swiss-Prot),   Q7TMZ3 (UniProtKB/Swiss-Prot),   A2AM77 (UniProtKB/Swiss-Prot),   Q91XU5 (UniProtKB/Swiss-Prot),   Q99MQ3 (UniProtKB/Swiss-Prot),   Q3U258 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000101442   ⟸   ENSMUST00000105816
RefSeq Acc Id: ENSMUSP00000101443   ⟸   ENSMUST00000105817
RefSeq Acc Id: ENSMUSP00000030536   ⟸   ENSMUST00000030536
RefSeq Acc Id: XP_036020293   ⟸   XM_036164400
- Peptide Label: isoform X1
- UniProtKB: Q3U258 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99MQ3-F1-model_v2 AlphaFold Q99MQ3 1-580 view protein structure

Promoters
RGD ID:6835854
Promoter ID:MM_KWN:40309
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung
Transcripts:ENSMUST00000105816
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364137,873,004 - 137,873,504 (-)MPROMDB
RGD ID:6847837
Promoter ID:MM_ACW:36205
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:PINK1.FSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364137,873,311 - 137,873,811 (-)MPROMDB
RGD ID:6835856
Promoter ID:MM_KWN:40310
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4
Transcripts:OTTMUST00000023184,   OTTMUST00000023185,   UC008VKV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364137,881,594 - 137,882,094 (-)MPROMDB
RGD ID:6885184
Promoter ID:EPDNEW_M6043
Type:initiation region
Name:Pink1_1
Description:Mus musculus PTEN induced putative kinase 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384138,326,271 - 138,326,331EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916193 AgrOrtholog
Ensembl Genes ENSMUSG00000028756 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000030536 ENTREZGENE
  ENSMUST00000030536.13 UniProtKB/Swiss-Prot
  ENSMUST00000105816.8 UniProtKB/TrEMBL
  ENSMUST00000105817.4 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kinase-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PINK1_STKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:68943 UniProtKB/Swiss-Prot
MGD MGI:1916193 ENTREZGENE
NCBI Gene 68943 ENTREZGENE
PANTHER SERINE/THREONINE PROTEIN KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE PINK1, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pink1 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AM76_MOUSE UniProtKB/TrEMBL
  A2AM77 ENTREZGENE
  A2AM78_MOUSE UniProtKB/TrEMBL
  PINK1_MOUSE UniProtKB/Swiss-Prot
  Q3U258 ENTREZGENE, UniProtKB/TrEMBL
  Q5DU52_MOUSE UniProtKB/TrEMBL
  Q6IS31_MOUSE UniProtKB/TrEMBL
  Q7TMZ3 ENTREZGENE
  Q811I8 ENTREZGENE
  Q91XU5 ENTREZGENE
  Q99MQ3 ENTREZGENE
UniProt Secondary A2AM77 UniProtKB/Swiss-Prot
  Q7TMZ3 UniProtKB/Swiss-Prot
  Q811I8 UniProtKB/Swiss-Prot
  Q91XU5 UniProtKB/Swiss-Prot