Gene: Tek (endothelial-specific receptor tyrosine kinase)  Mus musculus

Symbol: Tek
Name: endothelial-specific receptor tyrosine kinase
Description: ENCODES a protein that exhibits protein tyrosine kinase activity; receptor activity; growth factor binding (ortholog); INVOLVED IN angiogenesis; cell-cell adhesion; cell-matrix adhesion; PARTICIPATES IN angiopoietin signaling pathway; rheumatoid arthritis pathway; ASSOCIATED WITH abnormal angiogenesis; abnormal blood vessel morphology; abnormal cardiovascular development; ASSOCIATED WITH Acute Kidney Injury (ortholog); Arteriovenous Malformations (ortholog); Brain Ischemia (ortholog); FOUND IN apical plasma membrane (ortholog); basal plasma membrane (ortholog); basolateral plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA517024; angiopoietin-1 receptor; Cd202b; endothelial tyrosine kinase; Hyk; mTIE2; OTTMUSP00000008222; OTTMUSP00000008261; OTTMUSP00000008262; p140 TEK; STK1; tie-2; Tie2; tunica interna endothelial cell kinase; tyrosine kinase with Ig and EGF homology domains-2; tyrosine-protein kinase receptor TEK; tyrosine-protein kinase receptor TIE-2
Orthologs: Homo sapiens : TEK (TEK tyrosine kinase, endothelial)  HGNC
Rattus norvegicus : Tek (TEK tyrosine kinase, endothelial)
Related Pseudogenes: Gm12661  
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm38494,739,300 - 94,874,939+NCBI
Mouse cM Map443.34 NCBI
Mouse Celera Assembly493,148,719 - 93,271,150+NCBI
Mouse Genome Assembly Build 37494,405,991 - 94,541,630+NCBI
Mouse Genome Assembly Build 36.1494,405,991 - 94,541,630+NCBI
Mouse Cytogenetic Map4 C5 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tek
Entrez Gene
Ensembl Gene
Genome Browser
MGI Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1552464
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2013-04-30
Status: ACTIVE