Gene: Timp3 (tissue inhibitor of metalloproteinase 3)  Mus musculus

Symbol: Timp3
Name: tissue inhibitor of metalloproteinase 3
Description: ENCODES a protein that exhibits enzyme inhibitor activity (inferred); metal ion binding (inferred); metalloendopeptidase inhibitor activity (inferred); INVOLVED IN cellular response to organic substance; negative regulation of membrane protein ectodomain proteolysis (ortholog); negative regulation of proteolysis (ortholog); ASSOCIATED WITH abnormal apoptosis; abnormal branching involved in terminal bronchiole morphogenesis; abnormal bronchiole morphology; ASSOCIATED WITH Diabetes Mellitus, Experimental; Breast Neoplasms (ortholog); Carcinoma, Renal Cell (ortholog); FOUND IN basement membrane; cytoplasm (ortholog); INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: metalloproteinase inhibitor 3; OTTMUSP00000023387; Timp-3; tissue inhibitor of metalloproteinases 3
Orthologs: Homo sapiens : TIMP3 (TIMP metallopeptidase inhibitor 3)  HGNC
Rattus norvegicus : Timp3 (TIMP metallopeptidase inhibitor 3)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm381086,300,412 - 86,349,505+NCBI
Mouse cM Map1042.83 NCBI
Mouse Celera Assembly1088,278,411 - 88,327,541+NCBI
Mouse Genome Assembly Build 371085,763,157 - 85,812,250+NCBI
Mouse Genome Assembly Build 36.11085,763,157 - 85,812,250+NCBI
Mouse Cytogenetic Map10 C1-D1 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Timp3
Entrez Gene
Ensembl Gene
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MGI Report
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RGD Object Information
RGD ID: 11419
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2013-04-02
Status: ACTIVE