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ONTOLOGY REPORT - ANNOTATIONS

Term:metallopeptidase activity
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Accession:GO:0008237 term browser browse the term
Definition:Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
Synonyms:narrow_synonym: metalloprotease activity;   metalloproteinase activity
 xref: Reactome:R-HSA-2022368 "MME:Zn2+ hydrolyses AGT(34-42)";   Reactome:R-HSA-2022393 "ANPEP hydrolyzes Angiotensin-(2-8) to Angiotensin-(3-8)";   Reactome:R-HSA-2022396 "MME:Zn2+ hydrolyses AGT(34-43)";   Reactome:R-HSA-2022399 "ENPEP hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8)";   Reactome:R-HSA-5211340 "Anthrax lef cleaves target cell MAP2K1 (MEK1)";   Reactome:R-HSA-5211356 "Anthrax lef cleaves target cell MAP2K2 (MEK2)";   Reactome:R-HSA-5211387 "Anthrax lef cleaves target cell MAP2K7 (MEK7)";   Reactome:R-HSA-5211391 "Anthrax lef cleaves target cell MAP2K4 (MEK4)";   Reactome:R-HSA-5211400 "Anthrax lef cleaves target cell MAP2K3 (MEK3)";   Reactome:R-HSA-5211405 "Anthrax lef cleaves target cell MAP2K6 (MEK6)";   Reactome:R-HSA-9662837 "p-S,T-ADAM17(215-827):Zn2+ cleaves CD163";   Reactome:R-HSA-9759522 "Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform";   reactome:R-HSA-157629 "NOTCH2-ligand complex is cleaved to produce NEXT2";   reactome:R-HSA-157632 "Complex of NOTCH1 with its ligand is cleaved to produce NEXT1";   reactome:R-HSA-193679 "alpha-secretase cleaves the p75NTR extracellular domain";   reactome:R-HSA-2220944 "ADAM10/17 cleaves ligand-bound NOTCH1 PEST domain mutants to produce NEXT1 PEST domain mutants";   reactome:R-HSA-2220976 "NOTCH1 HD+PEST domain mutants are cleaved by ADAM10/17 irrespective of ligand binding";   reactome:R-HSA-2666278 "NOTCH1 t(7;9)(NOTCH1:M1580_K2555) is cleaved to produce NEXT1";   reactome:R-HSA-2730752 "NOTCH1 HD domain mutants are cleaved to produce NEXT1 irrespective of ligand binding";   reactome:R-HSA-3928660 "ADAM10 cleaves EFNAs";   reactome:R-HSA-8986181 "PITRM1 proteolyzes mitochondrial targeting peptides (presequences)";   reactome:R-HSA-9013284 "NOTCH3-ligand complex is cleaved to produce NEXT3";   reactome:R-HSA-9604264 "ADAM10 cleaves NOTCH4"


show annotations for term's descendants           Sort by:
metallopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme enables ISO
IEA
IBA
TAS
ISS
IDA		 (PMID:2554286)
(PMID:1320019), (PMID:1668266), (PMID:17077303), (PMID:2849100)		 RGD
TreeGrafter
GO_Central
Ensembl
InterPro
UniProt		 PMID:1320019 PMID:1668266 PMID:2554286 PMID:2849100 PMID:11299220 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 RGD:7401264 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACE2 angiotensin converting enzyme 2 enables IDA
IBA
IEA		 (PMID:10924499) UniProt
GO_Central
TreeGrafter
InterPro		 PMID:10924499 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ADAM10 ADAM metallopeptidase domain 10 enables IDA
IEA
IMP		 (PMID:12475894)
(PMID:12535668)		 UniProt
InterPro
Ensembl
BHF-UCL		 PMID:12475894 PMID:12535668 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr15:58,588,809...58,749,707
Ensembl chr15:58,588,809...58,749,791 		JBrowse link
G ADAM11 ADAM metallopeptidase domain 11 enables TAS (PMID:9693107) PINC PMID:9693107 NCBI chr17:44,758,988...44,781,846
Ensembl chr17:44,758,988...44,781,846 		JBrowse link
G ADAM12 ADAM metallopeptidase domain 12 enables IEA
TAS		 (PMID:9417060) UniProt
PINC		 PMID:9417060 GO_REF:0000043 NCBI chr10:126,012,391...126,388,477
Ensembl chr10:126,012,381...126,388,477 		JBrowse link
G ADAM15 ADAM metallopeptidase domain 15 enables TAS
IDA
IEA		 (PMID:9516430)
(PMID:12777399)		 PINC
BHF-UCL
UniProt		 PMID:9516430 PMID:12777399 GO_REF:0000043 NCBI chr 1:155,051,316...155,062,775
Ensembl chr 1:155,050,566...155,062,775 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 enables IMP
IEA
IDA		 (PMID:12535668)
(PMID:12777399)		 BHF-UCL
InterPro
UniProt		 PMID:12535668 PMID:12777399 GO_REF:0000002 GO_REF:0000043 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G ADAM18 ADAM metallopeptidase domain 18 enables TAS (PMID:10395895) PINC PMID:10395895 NCBI chr 8:39,584,568...39,730,065
Ensembl chr 8:39,584,489...39,730,065 		JBrowse link
G ADAM19 ADAM metallopeptidase domain 19 enables IEA UniProt GO_REF:0000043 NCBI chr 5:157,477,304...157,575,775
Ensembl chr 5:157,395,534...157,575,775 		JBrowse link
G ADAM2 ADAM metallopeptidase domain 2 enables TAS (PMID:9041139) PINC PMID:9041139 NCBI chr 8:39,743,735...39,838,227
Ensembl chr 8:39,743,735...39,838,227 		JBrowse link
G ADAM20 ADAM metallopeptidase domain 20 enables IEA
TAS		 (PMID:9469942) UniProt
PINC		 PMID:9469942 GO_REF:0000043 NCBI chr14:70,522,358...70,579,452
Ensembl chr14:70,522,358...70,535,015 		JBrowse link
G ADAM21 ADAM metallopeptidase domain 21 enables IEA
TAS		 (PMID:9469942) UniProt
PINC		 PMID:9469942 GO_REF:0000043 NCBI chr14:70,452,174...70,459,905
Ensembl chr14:70,417,107...70,460,427 		JBrowse link
G ADAM23 ADAM metallopeptidase domain 23 enables TAS (PMID:9693107) PINC PMID:9693107 NCBI chr 2:206,443,532...206,621,127
Ensembl chr 2:206,443,532...206,621,127 		JBrowse link
G ADAM28 ADAM metallopeptidase domain 28 enables TAS
IDA
IEA		 (PMID:10587367)
(PMID:12777399)		 PINC
BHF-UCL
UniProt		 PMID:10587367 PMID:12777399 GO_REF:0000043 NCBI chr 8:24,294,069...24,359,014
Ensembl chr 8:24,294,069...24,359,014 		JBrowse link
G ADAM29 ADAM metallopeptidase domain 29 enables TAS (PMID:10512762) PINC PMID:10512762 NCBI chr 4:174,918,358...174,978,180
Ensembl chr 4:174,829,668...174,978,180 		JBrowse link
G ADAM30 ADAM metallopeptidase domain 30 enables TAS
IEA		 (PMID:10512762) PINC
UniProt		 PMID:10512762 GO_REF:0000043 NCBI chr 1:119,893,533...119,896,515
Ensembl chr 1:119,893,533...119,896,515 		JBrowse link
G ADAM33 ADAM metallopeptidase domain 33 enables IEA UniProt GO_REF:0000043 NCBI chr20:3,667,975...3,682,010
Ensembl chr20:3,667,965...3,682,246 		JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 enables IEA
IDA		 (PMID:12777399), (PMID:15220135), (PMID:17548643) Ensembl
BHF-UCL
UniProt		 PMID:12777399 PMID:15220135 PMID:17548643 GO_REF:0000043 GO_REF:0000107 NCBI chr10:133,262,423...133,276,868
Ensembl chr10:133,262,420...133,276,868 		JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 enables IEA
IMP		 (PMID:12535668) UniProt
BHF-UCL		 PMID:12535668 GO_REF:0000043 NCBI chr 8:38,996,973...39,105,261
Ensembl chr 8:38,996,754...39,105,445 		JBrowse link
G ADAMDEC1 ADAM like decysin 1 enables IEA UniProt GO_REF:0000043 NCBI chr 8:24,384,285...24,406,013
Ensembl chr 8:24,384,285...24,406,013 		JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 enables TAS
IEA		 (PMID:10438512) PINC
UniProt		 PMID:10438512 GO_REF:0000043 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409 		JBrowse link
G ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif 10 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr19:8,580,240...8,610,715
Ensembl chr19:8,580,240...8,610,735 		JBrowse link
G ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif 12 enables IEA UniProt GO_REF:0000043 NCBI chr 5:33,523,535...33,891,990
Ensembl chr 5:33,523,535...33,892,019 		JBrowse link
G ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 enables TAS
IEA		 (PMID:11557746) UniProt
InterPro		 PMID:11557746 GO_REF:0000002 GO_REF:0000043 NCBI chr 9:133,414,337...133,459,386
Ensembl chr 9:133,414,358...133,459,402 		JBrowse link
G ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif 14 enables IEA UniProt GO_REF:0000043 NCBI chr10:70,672,506...70,762,441
Ensembl chr10:70,672,506...70,762,441 		JBrowse link
G ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif 15 enables IEA UniProt GO_REF:0000043 NCBI chr11:130,448,645...130,476,645
Ensembl chr11:130,448,645...130,476,645 		JBrowse link
G ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif 16 enables IEA UniProt GO_REF:0000043 NCBI chr 5:5,140,330...5,320,304
Ensembl chr 5:5,140,330...5,320,304 		JBrowse link
G ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif 17 enables IEA UniProt GO_REF:0000043 NCBI chr15:99,971,437...100,341,975
Ensembl chr15:99,971,437...100,342,005 		JBrowse link
G ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 enables IEA UniProt GO_REF:0000043 NCBI chr16:77,282,128...77,435,034
Ensembl chr16:77,247,813...77,435,034 		JBrowse link
G ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif 19 enables IEA UniProt GO_REF:0000043 NCBI chr 5:129,460,298...129,738,683
Ensembl chr 5:129,460,281...129,738,683 		JBrowse link
G ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif 2 enables TAS
IEA		 (PMID:10417273) PINC
UniProt		 PMID:10417273 GO_REF:0000043 NCBI chr 5:179,110,853...179,345,461
Ensembl chr 5:179,110,853...179,345,461 		JBrowse link
G ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif 20 enables IEA UniProt GO_REF:0000043 NCBI chr12:43,352,763...43,552,203
Ensembl chr12:43,353,866...43,552,203 		JBrowse link
G ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 enables IEA UniProt GO_REF:0000043 NCBI chr 4:72,280,969...72,569,221
Ensembl chr 4:72,280,969...72,569,221 		JBrowse link
G ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 enables IEA
IDA
TAS		 (PMID:21370305)
(PMID:10356395)		 InterPro
UniProt
PINC		 PMID:10356395 PMID:21370305 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:161,184,302...161,199,054
Ensembl chr 1:161,184,302...161,199,054 		JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 enables IEA
IDA
TAS		 (PMID:21370305), (PMID:33719441)
(PMID:10438522)		 UniProt
Ensembl
PINC		 PMID:10438522 PMID:21370305 PMID:33719441 GO_REF:0000043 GO_REF:0000107 NCBI chr21:26,917,922...26,967,088
Ensembl chr21:26,917,922...26,967,088 		JBrowse link
G ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif 6 enables TAS
IEA		 (PMID:10464288) PINC
UniProt		 PMID:10464288 GO_REF:0000043 NCBI chr 5:65,148,738...65,481,920
Ensembl chr 5:65,148,738...65,481,920 		JBrowse link
G ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif 7 enables IEA
TAS		 (PMID:10464288) Ensembl
UniProt
PINC		 PMID:10464288 GO_REF:0000043 GO_REF:0000107 NCBI chr15:78,759,206...78,811,464
Ensembl chr15:78,759,206...78,811,464 		JBrowse link
G ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif 8 enables TAS
IEA		 (PMID:10438512) PINC
UniProt		 PMID:10438512 GO_REF:0000043 NCBI chr11:130,404,923...130,428,609
Ensembl chr11:130,404,923...130,428,609 		JBrowse link
G ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 enables IDA
TAS
IEA		 (PMID:12514189)
(PMID:10936055)		 MGI
PINC
UniProt		 PMID:10936055 PMID:12514189 GO_REF:0000043 NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000 		JBrowse link
G AFG3L2 AFG3 like matrix AAA peptidase subunit 2 enables IMP
IEA		 (PMID:27642048) UniProt PMID:27642048 GO_REF:0000043 NCBI chr18:12,328,944...12,377,227
Ensembl chr18:12,328,944...12,377,227 		JBrowse link
G AGBL1 AGBL carboxypeptidase 1 enables IEA UniProt GO_REF:0000043 NCBI chr15:86,079,620...87,031,476
Ensembl chr15:86,079,871...87,049,169 		JBrowse link
G AGBL2 AGBL carboxypeptidase 2 enables IEA UniProt GO_REF:0000043 NCBI chr11:47,659,591...47,715,369
Ensembl chr11:47,659,591...47,715,389 		JBrowse link
G AGBL3 AGBL carboxypeptidase 3 enables IEA UniProt GO_REF:0000043 NCBI chr 7:134,986,508...135,135,778
Ensembl chr 7:134,986,508...135,147,963 		JBrowse link
G AGBL4 AGBL carboxypeptidase 4 enables IEA UniProt GO_REF:0000043 NCBI chr 1:48,522,511...50,023,954
Ensembl chr 1:48,532,854...50,023,954 		JBrowse link
G AGBL5 AGBL carboxypeptidase 5 enables IEA UniProt GO_REF:0000043 NCBI chr 2:27,050,364...27,070,618
Ensembl chr 2:27,042,364...27,070,622 		JBrowse link
G AGTPBP1 ATP/GTP binding carboxypeptidase 1 enables IEA UniProt GO_REF:0000043 NCBI chr 9:85,546,539...85,805,483
Ensembl chr 9:85,546,539...85,742,029 		JBrowse link
G AMZ1 archaelysin family metallopeptidase 1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 7:2,679,522...2,765,138
Ensembl chr 7:2,679,522...2,775,500 		JBrowse link
G AMZ2 archaelysin family metallopeptidase 2 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr17:68,206,129...68,257,164
Ensembl chr17:68,205,481...68,257,712 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane enables IEA
TAS		 (PMID:2564851) InterPro
UniProt
PINC		 PMID:2564851 GO_REF:0000002 GO_REF:0000043 NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401 		JBrowse link
G AOPEP aminopeptidase O (putative) enables IEA UniProt GO_REF:0000043 NCBI chr 9:94,726,699...95,150,224
Ensembl chr 9:94,726,604...95,151,793 		JBrowse link
G ASTL astacin like metalloendopeptidase enables IEA UniProt GO_REF:0000043 NCBI chr 2:96,122,818...96,138,564
Ensembl chr 2:96,122,818...96,138,502 		JBrowse link
G ATP23 ATP23 metallopeptidase and ATP synthase assembly factor homolog enables IEA UniProt GO_REF:0000043 NCBI chr12:57,941,567...57,959,148
Ensembl chr12:57,906,039...57,959,148 		JBrowse link
G BMP1 bone morphogenetic protein 1 enables NAS
IEA		 (PMID:7798260) UniProt PMID:7798260 GO_REF:0000043 NCBI chr 8:22,165,372...22,212,326
Ensembl chr 8:22,165,140...22,212,326 		JBrowse link
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 enables IEA
IBA
IMP		 (PMID:17525341), (PMID:19214193), (PMID:19261746) UniProt
GO_Central
InterPro		 PMID:17525341 PMID:19214193 PMID:19261746 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000104 NCBI chr  X:155,071,508...155,123,077
Ensembl chr  X:155,071,420...155,123,077 		JBrowse link
G CHMP1A charged multivesicular body protein 1A enables TAS (PMID:8863740) PINC PMID:8863740 NCBI chr16:89,644,435...89,657,708
Ensembl chr16:89,640,816...89,657,738 		JBrowse link
G CIROP ciliated left-right organizer metallopeptidase enables IEA UniProt GO_REF:0000043 NCBI chr14:23,099,062...23,104,989
Ensembl chr14:23,099,062...23,104,989 		JBrowse link
G CLCA1 chloride channel accessory 1 enables IEA UniProt GO_REF:0000043 NCBI chr 1:86,468,927...86,500,259
Ensembl chr 1:86,468,368...86,500,259 		JBrowse link
G CLCA2 chloride channel accessory 2 enables IEA UniProt GO_REF:0000043 NCBI chr 1:86,424,171...86,456,553
Ensembl chr 1:86,424,171...86,456,553 		JBrowse link
G CLCA4 chloride channel accessory 4 enables IEA UniProt GO_REF:0000043 NCBI chr 1:86,547,078...86,580,754
Ensembl chr 1:86,547,078...86,580,754 		JBrowse link
G CNDP1 carnosine dipeptidase 1 enables IEA UniProt GO_REF:0000043 NCBI chr18:74,534,500...74,587,212
Ensembl chr18:74,534,500...74,587,212 		JBrowse link
G CNDP2 carnosine dipeptidase 2 enables IEA UniProt GO_REF:0000043 NCBI chr18:74,496,363...74,523,454
Ensembl chr18:74,495,816...74,523,454 		JBrowse link
G COPS5 COP9 signalosome subunit 5 enables IMP
IEA
IBA		 (PMID:19214193) UniProt
TreeGrafter
GO_Central
InterPro		 PMID:19214193 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 8:67,043,079...67,062,133
Ensembl chr 8:67,043,079...67,083,783 		JBrowse link
G COPS6 COP9 signalosome subunit 6 enables IEA InterPro GO_REF:0000002 NCBI chr 7:100,088,969...100,092,187
Ensembl chr 7:100,088,969...100,092,187 		JBrowse link
G CPA1 carboxypeptidase A1 enables IEA UniProt GO_REF:0000043 NCBI chr 7:130,380,494...130,388,108
Ensembl chr 7:130,380,339...130,388,114 		JBrowse link
G CPA2 carboxypeptidase A2 enables IEA UniProt GO_REF:0000043 NCBI chr 7:130,266,863...130,289,798
Ensembl chr 7:130,266,863...130,289,798 		JBrowse link
G CPA3 carboxypeptidase A3 enables IEA UniProt GO_REF:0000043 NCBI chr 3:148,865,296...148,897,203
Ensembl chr 3:148,865,296...148,897,203 		JBrowse link
G CPA4 carboxypeptidase A4 enables IEA UniProt GO_REF:0000043 NCBI chr 7:130,293,161...130,324,180
Ensembl chr 7:130,293,134...130,324,180 		JBrowse link
G CPA5 carboxypeptidase A5 enables IEA UniProt GO_REF:0000043 NCBI chr 7:130,344,816...130,374,599
Ensembl chr 7:130,344,816...130,368,730 		JBrowse link
G CPA6 carboxypeptidase A6 enables IEA UniProt GO_REF:0000043 NCBI chr 8:67,422,038...67,746,360
Ensembl chr 8:67,422,038...67,746,378 		JBrowse link
G CPB1 carboxypeptidase B1 enables IEA UniProt GO_REF:0000043 NCBI chr 3:148,827,811...148,860,187
Ensembl chr 3:148,791,102...148,860,187 		JBrowse link
G CPB2 carboxypeptidase B2 enables IEA UniProt GO_REF:0000043 NCBI chr13:46,053,186...46,105,033
Ensembl chr13:46,053,186...46,105,033 		JBrowse link
G CPD carboxypeptidase D enables IEA UniProt GO_REF:0000043 NCBI chr17:30,378,927...30,469,989
Ensembl chr17:30,378,927...30,469,989 		JBrowse link
G CPE carboxypeptidase E enables IEA UniProt GO_REF:0000043 NCBI chr 4:165,379,008...165,498,547
Ensembl chr 4:165,361,194...165,498,547 		JBrowse link
G CPM carboxypeptidase M enables IEA UniProt GO_REF:0000043 NCBI chr12:68,842,197...68,963,469
Ensembl chr12:68,842,197...68,971,570 		JBrowse link
G CPN1 carboxypeptidase N subunit 1 enables IEA UniProt GO_REF:0000043 NCBI chr10:100,042,193...100,081,869
Ensembl chr10:100,042,193...100,081,869 		JBrowse link
G CPO carboxypeptidase O enables IEA UniProt GO_REF:0000043 NCBI chr 2:206,939,518...206,969,474
Ensembl chr 2:206,939,518...206,969,474 		JBrowse link
G CPQ carboxypeptidase Q enables IEA UniProt GO_REF:0000043 NCBI chr 8:96,645,242...97,143,501
Ensembl chr 8:96,645,242...97,149,654 		JBrowse link
G CPXM1 carboxypeptidase X, M14 family member 1 enables IEA UniProt GO_REF:0000043 NCBI chr20:2,794,074...2,800,627
Ensembl chr20:2,794,074...2,800,627 		JBrowse link
G CPZ carboxypeptidase Z enables IEA UniProt GO_REF:0000043 NCBI chr 4:8,592,765...8,619,752
Ensembl chr 4:8,592,660...8,619,759 		JBrowse link
G DNPEP aspartyl aminopeptidase enables IEA UniProt GO_REF:0000043 NCBI chr 2:219,372,043...219,400,007
Ensembl chr 2:219,372,043...219,400,022 		JBrowse link
G DPEP1 dipeptidase 1 enables IEA UniProt GO_REF:0000043 NCBI chr16:89,613,308...89,641,540
Ensembl chr16:89,613,308...89,638,456 		JBrowse link
G DPEP2 dipeptidase 2 enables IEA UniProt GO_REF:0000043 NCBI chr16:67,987,390...68,000,619
Ensembl chr16:67,987,394...68,000,586 		JBrowse link
G DPP3 dipeptidyl peptidase 3 enables IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr11:66,480,434...66,509,657
Ensembl chr11:66,480,013...66,509,657 		JBrowse link
G ECE1 endothelin converting enzyme 1 enables IEA UniProt GO_REF:0000043 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572 		JBrowse link
G ECE2 endothelin converting enzyme 2 enables IEA UniProt GO_REF:0000043 NCBI chr 3:184,276,022...184,293,031
Ensembl chr 3:184,276,011...184,293,031 		JBrowse link
G ECEL1 endothelin converting enzyme like 1 enables IEA
TAS		 (PMID:9931490) UniProt
PINC		 PMID:9931490 GO_REF:0000043 NCBI chr 2:232,479,827...232,487,834
Ensembl chr 2:232,479,827...232,487,834 		JBrowse link
G EEF1AKMT4-ECE2 EEF1AKMT4-ECE2 readthrough enables IEA UniProt GO_REF:0000043 NCBI chr 3:184,249,672...184,293,031
Ensembl chr 3:184,249,695...184,293,031 		JBrowse link
G EIF3F eukaryotic translation initiation factor 3 subunit F enables IEA InterPro GO_REF:0000002 NCBI chr11:7,987,337...8,001,852
Ensembl chr11:7,970,251...8,001,862 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H enables IEA
IBA		 InterPro
TreeGrafter
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:116,642,130...116,766,374
Ensembl chr 8:116,642,130...116,766,925 		JBrowse link
G ENPEP glutamyl aminopeptidase enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 4:110,476,155...110,565,285
Ensembl chr 4:110,365,733...110,565,285 		JBrowse link
G ERAP1 endoplasmic reticulum aminopeptidase 1 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 5:96,760,813...96,935,854
Ensembl chr 5:96,760,810...96,808,100 		JBrowse link
G ERAP2 endoplasmic reticulum aminopeptidase 2 enables IEA
IDA		 (PMID:12799365) UniProt
HGNC-UCL
InterPro		 PMID:12799365 GO_REF:0000002 GO_REF:0000043 NCBI chr 5:96,875,939...96,919,716
Ensembl chr 5:96,875,986...96,919,703 		JBrowse link
G ERMP1 endoplasmic reticulum metallopeptidase 1 enables IEA UniProt GO_REF:0000043 NCBI chr 9:5,784,572...5,867,091
Ensembl chr 9:5,749,832...5,879,537 		JBrowse link
G FOLH1 folate hydrolase 1 enables IEA UniProt GO_REF:0000043 NCBI chr11:49,145,092...49,208,602
Ensembl chr11:49,145,092...49,208,638 		JBrowse link
G FOLH1B folate hydrolase 1B (pseudogene) enables IEA UniProt GO_REF:0000043 NCBI chr11:89,659,268...89,698,718
Ensembl chr11:89,659,297...89,698,718
Ensembl chr11:89,659,297...89,698,718 		JBrowse link
G IDE insulin degrading enzyme enables IEA UniProt GO_REF:0000043 NCBI chr10:92,451,684...92,574,093
Ensembl chr10:92,451,684...92,574,096 		JBrowse link
G KEL Kell metallo-endopeptidase (Kell blood group) enables IEA UniProt
Ensembl		 GO_REF:0000043 GO_REF:0000107 NCBI chr 7:142,941,114...142,962,363
Ensembl chr 7:142,941,114...142,962,363 		JBrowse link
G LMLN leishmanolysin like peptidase enables IEA UniProt GO_REF:0000043 NCBI chr 3:197,960,217...198,043,720
Ensembl chr 3:197,960,200...198,043,720 		JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase enables IEA
TAS		 (PMID:9177475) UniProt
PINC
InterPro		 PMID:9177475 GO_REF:0000002 GO_REF:0000043 NCBI chr 5:96,936,080...97,037,513
Ensembl chr 5:96,935,394...97,037,513 		JBrowse link
G LTA4H leukotriene A4 hydrolase enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr12:96,000,753...96,043,520
Ensembl chr12:96,000,753...96,043,520 		JBrowse link
G LVRN laeverin enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 5:115,962,475...116,027,606
Ensembl chr 5:115,962,454...116,027,619 		JBrowse link
G MATCAP1 microtubule associated tyrosine carboxypeptidase 1 enables IEA UniProt GO_REF:0000043 NCBI chr16:67,175,599...67,183,963
Ensembl chr16:67,175,599...67,184,040 		JBrowse link
G MATCAP2 microtubule associated tyrosine carboxypeptidase 2 enables IEA UniProt GO_REF:0000043 NCBI chr 7:36,324,152...36,390,357
Ensembl chr 7:36,324,152...36,390,125 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 enables IEA UniProt GO_REF:0000043 NCBI chr  X:21,839,617...21,885,423
Ensembl chr  X:21,839,617...21,885,423 		JBrowse link
G MEP1A meprin A subunit alpha enables IEA
IDA		 (PMID:22923609) UniProt
MGI		 PMID:22923609 GO_REF:0000043 NCBI chr 6:46,793,389...46,845,984
Ensembl chr 6:46,793,389...46,839,778 		JBrowse link
G MEP1B meprin A subunit beta enables IEA UniProt GO_REF:0000043 NCBI chr18:32,190,039...32,220,404
Ensembl chr18:32,185,069...32,220,404 		JBrowse link
G MIPEP mitochondrial intermediate peptidase enables IEA UniProt GO_REF:0000043 NCBI chr13:23,730,189...23,889,400
Ensembl chr13:23,730,189...23,889,400 		JBrowse link
G MME membrane metalloendopeptidase enables IEA UniProt GO_REF:0000043 NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704 		JBrowse link
G MMEL1 membrane metalloendopeptidase like 1 enables IEA UniProt GO_REF:0000043 NCBI chr 1:2,590,639...2,633,016
Ensembl chr 1:2,590,639...2,633,016 		JBrowse link
G MMP1 matrix metallopeptidase 1 enables IEA UniProt GO_REF:0000043 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP10 matrix metallopeptidase 10 enables IEA UniProt GO_REF:0000043 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628 		JBrowse link
G MMP11 matrix metallopeptidase 11 enables IEA Ensembl
UniProt		 GO_REF:0000043 GO_REF:0000107 NCBI chr22:23,772,849...23,784,316
Ensembl chr22:23,768,226...23,784,316 		JBrowse link
G MMP12 matrix metallopeptidase 12 enables IEA UniProt GO_REF:0000043 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G MMP13 matrix metallopeptidase 13 enables IEA UniProt GO_REF:0000043 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
G MMP14 matrix metallopeptidase 14 enables IEA UniProt GO_REF:0000043 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041 		JBrowse link
G MMP15 matrix metallopeptidase 15 enables IEA UniProt GO_REF:0000043 NCBI chr16:58,025,754...58,046,901
Ensembl chr16:58,025,754...58,046,901 		JBrowse link
G MMP16 matrix metallopeptidase 16 enables IEA UniProt GO_REF:0000043 NCBI chr 8:88,032,011...88,327,483
Ensembl chr 8:88,032,011...88,328,025 		JBrowse link
G MMP17 matrix metallopeptidase 17 enables IEA UniProt GO_REF:0000043 NCBI chr12:131,828,393...131,851,771
Ensembl chr12:131,828,393...131,851,783 		JBrowse link
G MMP19 matrix metallopeptidase 19 enables IEA UniProt GO_REF:0000043 NCBI chr12:55,835,433...55,842,936
Ensembl chr12:55,835,433...55,842,966 		JBrowse link
G MMP2 matrix metallopeptidase 2 enables IEA
IDA		 (PMID:24236012) UniProt PMID:24236012 GO_REF:0000043 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP20 matrix metallopeptidase 20 enables IEA UniProt GO_REF:0000043 NCBI chr11:102,576,832...102,625,332
Ensembl chr11:102,576,832...102,625,332 		JBrowse link
G MMP21 matrix metallopeptidase 21 enables IEA UniProt GO_REF:0000043 NCBI chr10:125,766,453...125,775,821
Ensembl chr10:125,753,580...125,775,821 		JBrowse link
G MMP23B matrix metallopeptidase 23B enables IEA
NAS		 (PMID:9740677) UniProt PMID:9740677 GO_REF:0000043 NCBI chr 1:1,632,173...1,634,654
Ensembl chr 1:1,632,163...1,635,263 		JBrowse link
G MMP24 matrix metallopeptidase 24 enables IEA UniProt GO_REF:0000043 NCBI chr20:35,226,690...35,276,998
Ensembl chr20:35,226,690...35,276,998 		JBrowse link
G MMP25 matrix metallopeptidase 25 enables IEA UniProt GO_REF:0000043 NCBI chr16:3,046,561...3,060,726
Ensembl chr16:3,046,062...3,060,726 		JBrowse link
G MMP26 matrix metallopeptidase 26 enables IEA UniProt GO_REF:0000043 NCBI chr11:4,704,784...4,992,429
Ensembl chr11:4,704,784...4,992,431 		JBrowse link
G MMP27 matrix metallopeptidase 27 enables IEA UniProt GO_REF:0000043 NCBI chr11:102,691,487...102,705,769
Ensembl chr11:102,691,487...102,705,769 		JBrowse link
G MMP28 matrix metallopeptidase 28 enables IEA UniProt GO_REF:0000043 NCBI chr17:35,756,249...35,795,641
Ensembl chr17:35,756,249...35,795,707 		JBrowse link
G MMP3 matrix metallopeptidase 3 enables IEA
IDA		 (PMID:9573338) UniProt PMID:9573338 GO_REF:0000043 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP7 matrix metallopeptidase 7 enables IDA
IEA		 (PMID:15297466), (PMID:26482249) CAFA
UniProt		 PMID:15297466 PMID:26482249 GO_REF:0000043 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750 		JBrowse link
G MMP8 matrix metallopeptidase 8 enables ISO
IEA		 RGD
UniProt		 PMID:16153442 GO_REF:0000043 RGD:2298554 NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050 		JBrowse link
G MMP9 matrix metallopeptidase 9 enables ISO
IDA
IEA		 (PMID:24236012), (PMID:26514923) RGD
UniProt		 PMID:11826121 PMID:24236012 PMID:26514923 GO_REF:0000043 RGD:70539 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MPND MPN domain containing enables IEA
IBA		 UniProt
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 NCBI chr19:4,343,562...4,360,078
Ensembl chr19:4,343,527...4,360,086 		JBrowse link
G MYSM1 Myb like, SWIRM and MPN domains 1 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:58,654,743...58,700,062
Ensembl chr 1:58,643,440...58,700,090 		JBrowse link
G NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 enables IEA UniProt GO_REF:0000043 NCBI chr11:90,131,699...90,192,894
Ensembl chr11:90,131,515...90,192,894 		JBrowse link
G NAALADL1 N-acetylated alpha-linked acidic dipeptidase like 1 enables IEA UniProt GO_REF:0000043 NCBI chr11:65,044,818...65,061,203
Ensembl chr11:65,044,818...65,058,553 		JBrowse link
G NLN neurolysin enables IEA UniProt GO_REF:0000043 NCBI chr 5:65,722,205...65,829,283
Ensembl chr 5:65,722,205...65,871,725 		JBrowse link
G NPEPPS aminopeptidase puromycin sensitive enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr17:47,522,933...47,623,276
Ensembl chr17:47,522,942...47,624,665 		JBrowse link
G NPEPPSP1 NPEPPS pseudogene 1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr17:38,195,740...38,257,249
Ensembl chr17:38,195,703...38,257,381
Ensembl chr17:38,195,703...38,257,381 		JBrowse link
G NRDC nardilysin convertase enables IEA UniProt GO_REF:0000043 NCBI chr 1:51,789,210...51,878,727
Ensembl chr 1:51,789,191...51,878,805 		JBrowse link
G OMA1 OMA1 zinc metallopeptidase enables IEA UniProt GO_REF:0000043 NCBI chr 1:58,480,719...58,546,726
Ensembl chr 1:58,415,384...58,546,802 		JBrowse link
G PAPPA pappalysin 1 enables IEA
NAS
IDA		 (PMID:10913121)
(PMID:10077652)		 UniProt
InterPro		 PMID:10077652 PMID:10913121 GO_REF:0000002 GO_REF:0000043 NCBI chr 9:116,153,791...116,402,321
Ensembl chr 9:116,153,791...116,402,321 		JBrowse link
G PAPPA2 pappalysin 2 enables IEA
IDA		 (PMID:11264294) UniProt
InterPro		 PMID:11264294 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:176,463,175...176,845,601
Ensembl chr 1:176,463,171...176,845,601 		JBrowse link
G PEPD peptidase D enables IEA UniProt GO_REF:0000043 NCBI chr19:33,386,950...33,521,791
Ensembl chr19:33,386,950...33,521,823 		JBrowse link
G PHEX phosphate regulating endopeptidase X-linked enables IEA UniProt GO_REF:0000043 NCBI chr  X:22,032,325...22,251,310
Ensembl chr  X:22,032,325...22,494,713 		JBrowse link
G PITRM1 pitrilysin metallopeptidase 1 enables EXP
IEA		 (PMID:19962426), (PMID:26697887) Reactome
UniProt		 PMID:19962426 PMID:26697887 GO_REF:0000043 NCBI chr10:3,137,727...3,172,841
Ensembl chr10:3,137,728...3,172,841 		JBrowse link
G PMPCA peptidase, mitochondrial processing subunit alpha contributes_to ISO RGD PMID:7490252 RGD:13463461 NCBI chr 9:136,410,658...136,423,761
Ensembl chr 9:136,410,630...136,427,992 		JBrowse link
G PMPCB peptidase, mitochondrial processing subunit beta contributes_to
enables		 ISO
IEA		 RGD
UniProt		 PMID:7490252 GO_REF:0000043 RGD:13463461 NCBI chr 7:103,297,435...103,347,542
Ensembl chr 7:103,297,407...103,331,818 		JBrowse link
G PRPF8 pre-mRNA processing factor 8 enables IEA InterPro GO_REF:0000002 NCBI chr17:1,650,629...1,684,867
Ensembl chr17:1,650,629...1,684,867 		JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 enables TAS
IEA		 (PMID:19214193) UniProt
TreeGrafter
InterPro		 PMID:19214193 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 2:161,308,425...161,411,717
Ensembl chr 2:161,308,425...161,411,717 		JBrowse link
G PSMD7 proteasome 26S subunit, non-ATPase 7 enables IEA InterPro GO_REF:0000002 NCBI chr16:74,296,814...74,306,288
Ensembl chr16:74,296,814...74,306,288 		JBrowse link
G RNPEP arginyl aminopeptidase enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:201,982,648...202,006,143
Ensembl chr 1:201,982,372...202,006,147 		JBrowse link
G RNPEPL1 arginyl aminopeptidase like 1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 2:240,568,484...240,581,372
Ensembl chr 2:240,565,804...240,581,372 		JBrowse link
G SPG7 SPG7 matrix AAA peptidase subunit, paraplegin enables IEA UniProt GO_REF:0000043 NCBI chr16:89,490,970...89,499,282
Ensembl chr16:89,490,719...89,557,766 		JBrowse link
G SPG7 SPG7 matrix AAA peptidase subunit, paraplegin enables IEA UniProt GO_REF:0000043 NCBI chr16:89,508,388...89,557,768
Ensembl chr16:89,490,719...89,557,766 		JBrowse link
G SPRTN SprT-like N-terminal domain enables IEA UniProt GO_REF:0000043 NCBI chr 1:231,338,293...231,355,023
Ensembl chr 1:231,337,104...231,355,023 		JBrowse link
G STAMBP STAM binding protein enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 2:73,828,961...73,873,656
Ensembl chr 2:73,828,916...73,873,659 		JBrowse link
G STAMBPL1 STAM binding protein like 1 enables IEA UniProt GO_REF:0000043 NCBI chr10:88,880,245...88,923,487
Ensembl chr10:88,879,734...88,975,153 		JBrowse link
G THOP1 thimet oligopeptidase 1 enables IEA UniProt GO_REF:0000043 NCBI chr19:2,785,503...2,815,807
Ensembl chr19:2,785,503...2,815,807 		JBrowse link
G TLL1 tolloid like 1 enables IEA UniProt GO_REF:0000043 NCBI chr 4:165,873,237...166,104,457
Ensembl chr 4:165,873,237...166,104,457 		JBrowse link
G TLL2 tolloid like 2 enables IEA UniProt GO_REF:0000043 NCBI chr10:96,364,608...96,513,926
Ensembl chr10:96,364,608...96,513,926 		JBrowse link
G TRABD2A TraB domain containing 2A enables IEA UniProt GO_REF:0000043 NCBI chr 2:84,821,666...84,881,084
Ensembl chr 2:84,821,650...84,907,008 		JBrowse link
G TRABD2B TraB domain containing 2B enables IEA UniProt GO_REF:0000043 NCBI chr 1:47,760,528...47,997,385
Ensembl chr 1:47,760,528...47,997,385 		JBrowse link
G TRHDE thyrotropin releasing hormone degrading enzyme enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr12:72,087,266...72,670,758
Ensembl chr12:72,087,266...72,670,758 		JBrowse link
G XPNPEP1 X-prolyl aminopeptidase 1 enables IEA UniProt GO_REF:0000043 NCBI chr10:109,864,766...109,923,511
Ensembl chr10:109,864,766...109,923,553 		JBrowse link
G XPNPEP2 X-prolyl aminopeptidase 2 enables IEA UniProt GO_REF:0000043 NCBI chr  X:129,738,979...129,769,536
Ensembl chr  X:129,738,949...129,769,536 		JBrowse link
G XPNPEP3 X-prolyl aminopeptidase 3 enables IEA UniProt GO_REF:0000043 NCBI chr22:40,857,148...40,932,815
Ensembl chr22:40,857,077...40,932,815 		JBrowse link
G YME1L1 YME1 like 1 ATPase enables IEA UniProt GO_REF:0000043 NCBI chr10:27,110,111...27,154,384
Ensembl chr10:27,110,111...27,155,266 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 enables IEA UniProt GO_REF:0000043 NCBI chr 1:40,258,236...40,294,180
Ensembl chr 1:40,258,041...40,294,180 		JBrowse link
metal-dependent deubiquitinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCC3 BRCA1/BRCA2-containing complex subunit 3 enables IMP
IEA		 (PMID:19261746) UniProt PMID:19261746 GO_REF:0000117 NCBI chr  X:155,071,508...155,123,077
Ensembl chr  X:155,071,420...155,123,077 		JBrowse link
G COPS5 COP9 signalosome subunit 5 enables IDA
IEA		 (PMID:19246649) FlyBase
UniProt		 PMID:19246649 GO_REF:0000117 NCBI chr 8:67,043,079...67,062,133
Ensembl chr 8:67,043,079...67,083,783 		JBrowse link
G COPS6 COP9 signalosome subunit 6 NOT|enables IKR (PMID:17559875) FlyBase PMID:17559875 NCBI chr 7:100,088,969...100,092,187
Ensembl chr 7:100,088,969...100,092,187 		JBrowse link
G EIF3F eukaryotic translation initiation factor 3 subunit F enables IDA (PMID:21124883) FlyBase PMID:21124883 NCBI chr11:7,987,337...8,001,852
Ensembl chr11:7,970,251...8,001,862 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H enables IDA
IEA		 (PMID:32269044) FlyBase
UniProt		 PMID:32269044 GO_REF:0000117 NCBI chr 8:116,642,130...116,766,374
Ensembl chr 8:116,642,130...116,766,925 		JBrowse link
G MPND MPN domain containing enables IEA UniProt GO_REF:0000117 NCBI chr19:4,343,562...4,360,078
Ensembl chr19:4,343,527...4,360,086 		JBrowse link
G MYSM1 Myb like, SWIRM and MPN domains 1 enables IDA
IEA		 (PMID:17707232) UniProt PMID:17707232 GO_REF:0000117 NCBI chr 1:58,654,743...58,700,062
Ensembl chr 1:58,643,440...58,700,090 		JBrowse link
G PRPF8 pre-mRNA processing factor 8 NOT|enables IKR (PMID:17559875) FlyBase PMID:17559875 NCBI chr17:1,650,629...1,684,867
Ensembl chr17:1,650,629...1,684,867 		JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 enables TAS
IBA
IEA
IMP		 (PMID:19214193)
(PMID:22909820)		 UniProt
GO_Central		 PMID:19214193 PMID:22909820 GO_REF:0000033 GO_REF:0000117 NCBI chr 2:161,308,425...161,411,717
Ensembl chr 2:161,308,425...161,411,717 		JBrowse link
G PSMD7 proteasome 26S subunit, non-ATPase 7 NOT|enables IKR (PMID:17559875) FlyBase PMID:17559875 NCBI chr16:74,296,814...74,306,288
Ensembl chr16:74,296,814...74,306,288 		JBrowse link
G STAMBP STAM binding protein enables IEA InterPro GO_REF:0000002 NCBI chr 2:73,828,961...73,873,656
Ensembl chr 2:73,828,916...73,873,659 		JBrowse link
G STAMBPL1 STAM binding protein like 1 enables IEA InterPro GO_REF:0000002 NCBI chr10:88,880,245...88,923,487
Ensembl chr10:88,879,734...88,975,153 		JBrowse link
metalloaminopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANPEP alanyl aminopeptidase, membrane enables IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401 		JBrowse link
G AOPEP aminopeptidase O (putative) enables IEA InterPro GO_REF:0000002 NCBI chr 9:94,726,699...95,150,224
Ensembl chr 9:94,726,604...95,151,793 		JBrowse link
G DNPEP aspartyl aminopeptidase enables IEA TreeGrafter GO_REF:0000118 NCBI chr 2:219,372,043...219,400,007
Ensembl chr 2:219,372,043...219,400,022 		JBrowse link
G ENPEP glutamyl aminopeptidase enables IDA
IEA
IBA
NAS		 (PMID:23888046), (PMID:8346219)
(PMID:8244382)		 UniProt
TreeGrafter
GO_Central		 PMID:8244382 PMID:8346219 PMID:23888046 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:110,476,155...110,565,285
Ensembl chr 4:110,365,733...110,565,285 		JBrowse link
G ERAP1 endoplasmic reticulum aminopeptidase 1 enables IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:96,760,813...96,935,854
Ensembl chr 5:96,760,810...96,808,100 		JBrowse link
G ERAP2 endoplasmic reticulum aminopeptidase 2 enables IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:96,875,939...96,919,716
Ensembl chr 5:96,875,986...96,919,703 		JBrowse link
G LAP3 leucine aminopeptidase 3 enables IEA InterPro GO_REF:0000002 NCBI chr 4:17,577,198...17,607,970
Ensembl chr 4:17,577,198...17,607,972 		JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase enables IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:96,936,080...97,037,513
Ensembl chr 5:96,935,394...97,037,513 		JBrowse link
G LTA4H leukotriene A4 hydrolase enables IMP
IEA		 (PMID:11675384) CAFA
TreeGrafter		 PMID:11675384 GO_REF:0000118 NCBI chr12:96,000,753...96,043,520
Ensembl chr12:96,000,753...96,043,520 		JBrowse link
G LVRN laeverin enables IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:115,962,475...116,027,606
Ensembl chr 5:115,962,454...116,027,619 		JBrowse link
G METAP1 methionyl aminopeptidase 1 enables IEA
IBA		 UniProt
GO_Central
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 NCBI chr 4:98,995,721...99,062,809
Ensembl chr 4:98,995,659...99,062,809 		JBrowse link
G METAP1D methionyl aminopeptidase type 1D, mitochondrial enables IEA
IBA		 InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 2:171,999,953...172,082,430
Ensembl chr 2:171,999,943...172,082,430 		JBrowse link
G METAP2 methionyl aminopeptidase 2 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr12:95,474,152...95,515,839
Ensembl chr12:95,473,520...95,515,839 		JBrowse link
G MMP14 matrix metallopeptidase 14 enables IDA
TAS		 (PMID:24970228)
(PMID:14645246)		 ParkinsonsUK-UCL PMID:14645246 PMID:24970228 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041 		JBrowse link
G MMP15 matrix metallopeptidase 15 enables TAS (PMID:14645246) ParkinsonsUK-UCL PMID:14645246 NCBI chr16:58,025,754...58,046,901
Ensembl chr16:58,025,754...58,046,901 		JBrowse link
G MMP16 matrix metallopeptidase 16 enables TAS
IDA		 (PMID:14645246)
(PMID:24970228)		 ParkinsonsUK-UCL PMID:14645246 PMID:24970228 NCBI chr 8:88,032,011...88,327,483
Ensembl chr 8:88,032,011...88,328,025 		JBrowse link
G MMP17 matrix metallopeptidase 17 enables TAS (PMID:14645246) ParkinsonsUK-UCL PMID:14645246 NCBI chr12:131,828,393...131,851,771
Ensembl chr12:131,828,393...131,851,783 		JBrowse link
G NPEPL1 aminopeptidase like 1 enables IEA InterPro GO_REF:0000002 NCBI chr20:58,689,131...58,715,844
Ensembl chr20:58,689,131...58,719,238 		JBrowse link
G NPEPPS aminopeptidase puromycin sensitive enables IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr17:47,522,933...47,623,276
Ensembl chr17:47,522,942...47,624,665 		JBrowse link
G NPEPPSP1 NPEPPS pseudogene 1 enables IBA GO_Central GO_REF:0000033 NCBI chr17:38,195,740...38,257,249
Ensembl chr17:38,195,703...38,257,381
Ensembl chr17:38,195,703...38,257,381 		JBrowse link
G PEPD peptidase D enables IEA InterPro GO_REF:0000002 NCBI chr19:33,386,950...33,521,791
Ensembl chr19:33,386,950...33,521,823 		JBrowse link
G RNPEP arginyl aminopeptidase enables ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central		 PMID:17142967 GO_REF:0000033 GO_REF:0000118 RGD:2325932 NCBI chr 1:201,982,648...202,006,143
Ensembl chr 1:201,982,372...202,006,147 		JBrowse link
G RNPEPL1 arginyl aminopeptidase like 1 enables IDA
IEA
IBA		 (PMID:11017071) UniProt
TreeGrafter
GO_Central		 PMID:11017071 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:240,568,484...240,581,372
Ensembl chr 2:240,565,804...240,581,372 		JBrowse link
G TRHDE thyrotropin releasing hormone degrading enzyme enables IBA GO_Central GO_REF:0000033 NCBI chr12:72,087,266...72,670,758
Ensembl chr12:72,087,266...72,670,758 		JBrowse link
G XPNPEP1 X-prolyl aminopeptidase 1 enables IEA
IDA		 (PMID:18515364), (PMID:35165443) InterPro
UniProt		 PMID:18515364 PMID:35165443 GO_REF:0000002 NCBI chr10:109,864,766...109,923,511
Ensembl chr10:109,864,766...109,923,553 		JBrowse link
G XPNPEP2 X-prolyl aminopeptidase 2 enables IEA InterPro GO_REF:0000002 NCBI chr  X:129,738,979...129,769,536
Ensembl chr  X:129,738,949...129,769,536 		JBrowse link
G XPNPEP3 X-prolyl aminopeptidase 3 enables IDA
IEA		 (PMID:25609706), (PMID:28476889) UniProt
InterPro		 PMID:25609706 PMID:28476889 GO_REF:0000002 NCBI chr22:40,857,148...40,932,815
Ensembl chr22:40,857,077...40,932,815 		JBrowse link
metallocarboxypeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 enables EXP (PMID:10924499), (PMID:10969042), (PMID:11815627) Reactome PMID:10924499 PMID:10969042 PMID:11815627 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G AEBP1 AE binding protein 1 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 7:44,104,345...44,114,560
Ensembl chr 7:44,104,345...44,114,562 		JBrowse link
G AGBL1 AGBL carboxypeptidase 1 enables ISS
IEA		 UniProt
InterPro		 GO_REF:0000002 GO_REF:0000024 NCBI chr15:86,079,620...87,031,476
Ensembl chr15:86,079,871...87,049,169 		JBrowse link
G AGBL2 AGBL carboxypeptidase 2 enables IEA
ISS		 InterPro
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr11:47,659,591...47,715,369
Ensembl chr11:47,659,591...47,715,389 		JBrowse link
G AGBL3 AGBL carboxypeptidase 3 enables IEA
IDA		 (PMID:17244817), (PMID:25103237) InterPro
UniProt
Ensembl		 PMID:17244817 PMID:25103237 GO_REF:0000002 GO_REF:0000107 NCBI chr 7:134,986,508...135,135,778
Ensembl chr 7:134,986,508...135,147,963 		JBrowse link
G AGBL4 AGBL carboxypeptidase 4 enables ISS
IEA		 UniProt
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:48,522,511...50,023,954
Ensembl chr 1:48,532,854...50,023,954 		JBrowse link
G AGBL5 AGBL carboxypeptidase 5 enables ISS
IEA		 UniProt
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:27,050,364...27,070,618
Ensembl chr 2:27,042,364...27,070,622 		JBrowse link
G AGTPBP1 ATP/GTP binding carboxypeptidase 1 enables IEA
ISS
IDA		 (PMID:22170066) InterPro
UniProt
Ensembl		 PMID:22170066 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:85,546,539...85,805,483
Ensembl chr 9:85,546,539...85,742,029 		JBrowse link
G CPA1 carboxypeptidase A1 enables IEA
IBA
IDA
TAS		 (PMID:20385563)
(PMID:2920728)		 InterPro
TreeGrafter
GO_Central
UniProt
PINC		 PMID:2920728 PMID:20385563 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:130,380,494...130,388,108
Ensembl chr 7:130,380,339...130,388,114 		JBrowse link
G CPA2 carboxypeptidase A2 enables IEA
IBA
IDA
TAS		 (PMID:20385563), (PMID:2920728)
(PMID:2920728)		 InterPro
GO_Central
TreeGrafter
UniProt
PINC		 PMID:2920728 PMID:20385563 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:130,266,863...130,289,798
Ensembl chr 7:130,266,863...130,289,798 		JBrowse link
G CPA3 carboxypeptidase A3 enables NAS
IEA
IBA
TAS
EXP		 (PMID:2594780)
(PMID:1629626)
(PMID:2708524)		 UniProt
TreeGrafter
GO_Central
Reactome
InterPro		 PMID:1629626 PMID:2594780 PMID:2708524 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:148,865,296...148,897,203
Ensembl chr 3:148,865,296...148,897,203 		JBrowse link
G CPA4 carboxypeptidase A4 enables IEA
IBA
IDA
NAS		 (PMID:20385563)
(PMID:10383164)		 InterPro
GO_Central
TreeGrafter
UniProt		 PMID:10383164 PMID:20385563 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:130,293,161...130,324,180
Ensembl chr 7:130,293,134...130,324,180 		JBrowse link
G CPA5 carboxypeptidase A5 enables IEA
IBA		 InterPro
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:130,344,816...130,374,599
Ensembl chr 7:130,344,816...130,368,730 		JBrowse link
G CPA6 carboxypeptidase A6 enables IEA
IBA
NAS		 (PMID:11836249) InterPro
GO_Central
UniProt		 PMID:11836249 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:67,422,038...67,746,360
Ensembl chr 8:67,422,038...67,746,378 		JBrowse link
G CPB1 carboxypeptidase B1 enables IEA
IBA		 InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr 3:148,827,811...148,860,187
Ensembl chr 3:148,791,102...148,860,187 		JBrowse link
G CPB2 carboxypeptidase B2 enables TAS
IBA
IEA		 (PMID:10651877), (PMID:1939207) PINC
GO_Central
InterPro		 PMID:1939207 PMID:10651877 GO_REF:0000002 GO_REF:0000033 NCBI chr13:46,053,186...46,105,033
Ensembl chr13:46,053,186...46,105,033 		JBrowse link
G CPD carboxypeptidase D enables IEA
IBA		 UniProt
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr17:30,378,927...30,469,989
Ensembl chr17:30,378,927...30,469,989 		JBrowse link
G CPE carboxypeptidase E enables IEA
IBA		 InterPro
GO_Central
TreeGrafter
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:165,379,008...165,498,547
Ensembl chr 4:165,361,194...165,498,547 		JBrowse link
G CPM carboxypeptidase M enables IEA
IBA
TAS		 (PMID:2753907) InterPro
GO_Central
PINC		 PMID:2753907 GO_REF:0000002 GO_REF:0000033 NCBI chr12:68,842,197...68,963,469
Ensembl chr12:68,842,197...68,971,570 		JBrowse link
G CPN1 carboxypeptidase N subunit 1 enables IEA
IBA
TAS		 (PMID:2912725) UniProt
GO_Central
InterPro
PINC		 PMID:2912725 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr10:100,042,193...100,081,869
Ensembl chr10:100,042,193...100,081,869 		JBrowse link
G CPO carboxypeptidase O enables IDA
IBA
IEA		 (PMID:21921028) UniProt
GO_Central
InterPro		 PMID:21921028 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:206,939,518...206,969,474
Ensembl chr 2:206,939,518...206,969,474 		JBrowse link
G CPXM1 carboxypeptidase X, M14 family member 1 enables IEA InterPro GO_REF:0000002 NCBI chr20:2,794,074...2,800,627
Ensembl chr20:2,794,074...2,800,627 		JBrowse link
G CPXM2 carboxypeptidase X, M14 family member 2 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr10:123,745,639...123,944,104
Ensembl chr10:123,706,207...123,940,267 		JBrowse link
G CPZ carboxypeptidase Z enables TAS
IEA
IBA		 (PMID:9099699) PINC
TreeGrafter
GO_Central
InterPro		 PMID:9099699 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:8,592,765...8,619,752
Ensembl chr 4:8,592,660...8,619,759 		JBrowse link
G FOLH1 folate hydrolase 1 enables IEA
IDA		 (PMID:12949938), (PMID:17241121), (PMID:24863754) UniProt
BHF-UCL		 PMID:12949938 PMID:17241121 PMID:24863754 GO_REF:0000003 NCBI chr11:49,145,092...49,208,602
Ensembl chr11:49,145,092...49,208,638 		JBrowse link
G FOLH1B folate hydrolase 1B (pseudogene) enables IDA (PMID:17241121) BHF-UCL PMID:17241121 NCBI chr11:89,659,268...89,698,718
Ensembl chr11:89,659,297...89,698,718
Ensembl chr11:89,659,297...89,698,718 		JBrowse link
G MATCAP1 microtubule associated tyrosine carboxypeptidase 1 enables IDA (PMID:35482892) UniProt PMID:35482892 NCBI chr16:67,175,599...67,183,963
Ensembl chr16:67,175,599...67,184,040 		JBrowse link
G NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 enables IEA UniProt GO_REF:0000003 NCBI chr11:90,131,699...90,192,894
Ensembl chr11:90,131,515...90,192,894 		JBrowse link
G PEPD peptidase D enables TAS (PMID:1972707) PINC PMID:1972707 NCBI chr19:33,386,950...33,521,791
Ensembl chr19:33,386,950...33,521,823 		JBrowse link
G VASH1 vasohibin 1 enables IEA
IMP
IDA		 (PMID:31171830), (PMID:31235911)
(PMID:29146869)		 Ensembl
UniProt		 PMID:29146869 PMID:31171830 PMID:31235911 GO_REF:0000107 NCBI chr14:76,761,468...76,783,015
Ensembl chr14:76,761,468...76,783,015 		JBrowse link
G VASH2 vasohibin 2 enables IDA
IEA
IMP		 (PMID:29146869)
(PMID:31171830), (PMID:31235911)		 UniProt
Ensembl		 PMID:29146869 PMID:31171830 PMID:31235911 GO_REF:0000107 NCBI chr 1:212,950,541...212,991,585
Ensembl chr 1:212,950,520...212,992,037 		JBrowse link
metallodipeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme enables EXP
IDA		 (PMID:1848554), (PMID:1851160), (PMID:20011602), (PMID:2846041)
(PMID:7961923)		 Reactome
UniProt		 PMID:1848554 PMID:1851160 PMID:2846041 PMID:7961923 PMID:20011602 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ADAM10 ADAM metallopeptidase domain 10 enables IEA Ensembl GO_REF:0000107 NCBI chr15:58,588,809...58,749,707
Ensembl chr15:58,588,809...58,749,791 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 enables ISO (PMID:14993236) MGI PMID:14993236 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G CNDP1 carnosine dipeptidase 1 enables IEA InterPro GO_REF:0000002 NCBI chr18:74,534,500...74,587,212
Ensembl chr18:74,534,500...74,587,212 		JBrowse link
G CNDP2 carnosine dipeptidase 2 enables IEA InterPro GO_REF:0000002 NCBI chr18:74,496,363...74,523,454
Ensembl chr18:74,495,816...74,523,454 		JBrowse link
G CPQ carboxypeptidase Q enables IDA
IBA
IEA		 (PMID:10206990) UniProt
GO_Central
TreeGrafter
InterPro		 PMID:10206990 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:96,645,242...97,143,501
Ensembl chr 8:96,645,242...97,149,654 		JBrowse link
G DPEP1 dipeptidase 1 enables IDA
IEA		 (PMID:12144777), (PMID:19879002) UniProt
InterPro		 PMID:12144777 PMID:19879002 GO_REF:0000002 NCBI chr16:89,613,308...89,641,540
Ensembl chr16:89,613,308...89,638,456 		JBrowse link
G DPEP2 dipeptidase 2 enables IEA InterPro GO_REF:0000002 NCBI chr16:67,987,390...68,000,619
Ensembl chr16:67,987,394...68,000,586 		JBrowse link
G DPEP3 dipeptidase 3 enables IEA InterPro GO_REF:0000002 NCBI chr16:67,975,663...67,980,499
Ensembl chr16:67,975,663...67,980,549 		JBrowse link
G MEP1A meprin A subunit alpha enables IDA (PMID:22923609) MGI PMID:22923609 NCBI chr 6:46,793,389...46,845,984
Ensembl chr 6:46,793,389...46,839,778 		JBrowse link
metalloendopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme enables IDA (PMID:6208535), (PMID:7683654) UniProt PMID:6208535 PMID:7683654 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ADAM10 ADAM metallopeptidase domain 10 enables ISO
IEA
NAS
IMP
IDA
ISS
TAS		 (PMID:8694785)
(PMID:19114711)
(PMID:18676862)		 RGD
InterPro
UniProt
BHF-UCL
ARUK-UCL
Reactome		 PMID:8694785 PMID:10423016 PMID:18676862 PMID:19114711 GO_REF:0000002 GO_REF:0000024 RGD:631800 Reactome:R-HSA-4224014 NCBI chr15:58,588,809...58,749,707
Ensembl chr15:58,588,809...58,749,791 		JBrowse link
G ADAM11 ADAM metallopeptidase domain 11 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr17:44,758,988...44,781,846
Ensembl chr17:44,758,988...44,781,846 		JBrowse link
G ADAM12 ADAM metallopeptidase domain 12 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:126,012,391...126,388,477
Ensembl chr10:126,012,381...126,388,477 		JBrowse link
G ADAM15 ADAM metallopeptidase domain 15 enables TAS
IBA
IEA		 Reactome
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Reactome:R-HSA-4224014 NCBI chr 1:155,051,316...155,062,775
Ensembl chr 1:155,050,566...155,062,775 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 enables TAS
IEA
IBA
IDA
IMP		 (PMID:14625290), (PMID:15691827), (PMID:17010968), (PMID:24226769), (PMID:24337742), (PMID:36476876), (PMID:9774383), (PMID:9920899)
(PMID:9034190), (PMID:9034191)		 Reactome
TreeGrafter
GO_Central
BHF-UCL
InterPro		 PMID:9034190 PMID:9034191 PMID:9774383 PMID:9920899 PMID:14625290 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 Reactome:R-NUL-5362792 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G ADAM18 ADAM metallopeptidase domain 18 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:39,584,568...39,730,065
Ensembl chr 8:39,584,489...39,730,065 		JBrowse link
G ADAM19 ADAM metallopeptidase domain 19 enables IMP
IBA
IEA		 (PMID:11162584), (PMID:17112471) ARUK-UCL
GO_Central
InterPro		 PMID:11162584 PMID:17112471 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:157,477,304...157,575,775
Ensembl chr 5:157,395,534...157,575,775 		JBrowse link
G ADAM2 ADAM metallopeptidase domain 2 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:39,743,735...39,838,227
Ensembl chr 8:39,743,735...39,838,227 		JBrowse link
G ADAM20 ADAM metallopeptidase domain 20 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr14:70,522,358...70,579,452
Ensembl chr14:70,522,358...70,535,015 		JBrowse link
G ADAM21 ADAM metallopeptidase domain 21 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr14:70,452,174...70,459,905
Ensembl chr14:70,417,107...70,460,427 		JBrowse link
G ADAM22 ADAM metallopeptidase domain 22 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 7:87,934,251...88,202,889
Ensembl chr 7:87,934,143...88,202,889 		JBrowse link
G ADAM23 ADAM metallopeptidase domain 23 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:206,443,532...206,621,127
Ensembl chr 2:206,443,532...206,621,127 		JBrowse link
G ADAM28 ADAM metallopeptidase domain 28 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:24,294,069...24,359,014
Ensembl chr 8:24,294,069...24,359,014 		JBrowse link
G ADAM29 ADAM metallopeptidase domain 29 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:174,918,358...174,978,180
Ensembl chr 4:174,829,668...174,978,180 		JBrowse link
G ADAM30 ADAM metallopeptidase domain 30 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:119,893,533...119,896,515
Ensembl chr 1:119,893,533...119,896,515 		JBrowse link
G ADAM32 ADAM metallopeptidase domain 32 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:39,107,529...39,284,917
Ensembl chr 8:39,106,990...39,284,917 		JBrowse link
G ADAM33 ADAM metallopeptidase domain 33 enables NAS
IBA
IEA		 (PMID:11814695) UniProt
GO_Central
InterPro		 PMID:11814695 GO_REF:0000002 GO_REF:0000033 NCBI chr20:3,667,975...3,682,010
Ensembl chr20:3,667,965...3,682,246 		JBrowse link
G ADAM7 ADAM metallopeptidase domain 7 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:24,441,026...24,509,565
Ensembl chr 8:24,440,930...24,526,970 		JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:133,262,423...133,276,868
Ensembl chr10:133,262,420...133,276,868 		JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 enables IMP
IBA
IEA
IDA		 (PMID:22480688)
(PMID:12054541), (PMID:9920899)		 BHF-UCL
GO_Central
InterPro
ARUK-UCL		 PMID:9920899 PMID:12054541 PMID:22480688 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:38,996,973...39,105,261
Ensembl chr 8:38,996,754...39,105,445 		JBrowse link
G ADAMDEC1 ADAM like decysin 1 enables NAS
IBA
IEA		 (PMID:12037602), (PMID:9271581) UniProt
GO_Central
InterPro		 PMID:9271581 PMID:12037602 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:24,384,285...24,406,013
Ensembl chr 8:24,384,285...24,406,013 		JBrowse link
G ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif 1 enables IEA
IBA
IDA		 (PMID:11278559), (PMID:25122765) Ensembl
GO_Central
TreeGrafter
UniProt
InterPro		 PMID:11278559 PMID:25122765 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr21:26,835,755...26,845,409
Ensembl chr21:26,835,755...26,845,409 		JBrowse link
G ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif 10 enables IEA
IBA		 InterPro
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr19:8,580,240...8,610,715
Ensembl chr19:8,580,240...8,610,735 		JBrowse link
G ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif 12 enables IDA
IBA
IEA		 (PMID:16611630), (PMID:17895370), (PMID:18485748) BHF-UCL
GO_Central
InterPro		 PMID:16611630 PMID:17895370 PMID:18485748 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:33,523,535...33,891,990
Ensembl chr 5:33,523,535...33,892,019 		JBrowse link
G ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 enables IEA
IBA
TAS
EXP		 (PMID:12775718), (PMID:18983500), (PMID:31439947) InterPro
GO_Central
Reactome
TreeGrafter		 PMID:12775718 PMID:18983500 PMID:31439947 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-9824402 Reactome:R-HSA-9844241 NCBI chr 9:133,414,337...133,459,386
Ensembl chr 9:133,414,358...133,459,402 		JBrowse link
G ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif 14 enables TAS
IBA
IEA		 Reactome
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 Reactome:R-HSA-2002428 NCBI chr10:70,672,506...70,762,441
Ensembl chr10:70,672,506...70,762,441 		JBrowse link
G ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif 15 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr11:130,448,645...130,476,645
Ensembl chr11:130,448,645...130,476,645 		JBrowse link
G ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif 16 enables IEA
IBA		 InterPro
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:5,140,330...5,320,304
Ensembl chr 5:5,140,330...5,320,304 		JBrowse link
G ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif 17 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr15:99,971,437...100,341,975
Ensembl chr15:99,971,437...100,342,005 		JBrowse link
G ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 enables IEA
IBA		 InterPro
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr16:77,282,128...77,435,034
Ensembl chr16:77,247,813...77,435,034 		JBrowse link
G ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif 19 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:129,460,298...129,738,683
Ensembl chr 5:129,460,281...129,738,683 		JBrowse link
G ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif 2 enables TAS
IBA
IEA		 (PMID:10417273) PINC
GO_Central
InterPro
UniProt		 PMID:10417273 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 Reactome:R-HSA-2002428 NCBI chr 5:179,110,853...179,345,461
Ensembl chr 5:179,110,853...179,345,461 		JBrowse link
G ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif 20 enables IEA
IBA		 Ensembl
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr12:43,352,763...43,552,203
Ensembl chr12:43,353,866...43,552,203 		JBrowse link
G ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 enables TAS
IBA
IEA
NAS		 (PMID:11812023) Reactome
GO_Central
TreeGrafter
InterPro
UniProt		 PMID:11812023 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-2002428 NCBI chr 4:72,280,969...72,569,221
Ensembl chr 4:72,280,969...72,569,221 		JBrowse link
G ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 enables TAS
IBA
IEA		 Reactome
GO_Central
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-3788075 Reactome:R-NUL-2533988 NCBI chr 1:161,184,302...161,199,054
Ensembl chr 1:161,184,302...161,199,054 		JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 enables TAS
IBA
IDA
IEA		 (PMID:25122765), (PMID:26668318) Reactome
GO_Central
UniProt
InterPro		 PMID:25122765 PMID:26668318 GO_REF:0000002 GO_REF:0000033 Reactome:R-HSA-3788075 Reactome:R-NUL-2533988 NCBI chr21:26,917,922...26,967,088
Ensembl chr21:26,917,922...26,967,088 		JBrowse link
G ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif 6 enables IEA
IBA		 InterPro
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:65,148,738...65,481,920
Ensembl chr 5:65,148,738...65,481,920 		JBrowse link
G ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif 7 enables IDA
IBA
IEA		 (PMID:18485748) BHF-UCL
GO_Central
TreeGrafter
InterPro		 PMID:18485748 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr15:78,759,206...78,811,464
Ensembl chr15:78,759,206...78,811,464 		JBrowse link
G ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif 8 enables IEA
IBA		 InterPro
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr11:130,404,923...130,428,609
Ensembl chr11:130,404,923...130,428,609 		JBrowse link
G ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000 		JBrowse link
G ADAMTSL2 ADAMTS like 2 NOT|enables IBA GO_Central GO_REF:0000033 NCBI chr 9:133,532,164...133,575,519
Ensembl chr 9:133,532,164...133,575,519 		JBrowse link
G ADAMTSL4 ADAMTS like 4 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:150,549,408...150,560,937
Ensembl chr 1:150,549,369...150,560,937 		JBrowse link
G ADAMTSL5 ADAMTS like 5 enables IEA TreeGrafter GO_REF:0000118 NCBI chr19:1,505,022...1,513,019
Ensembl chr19:1,505,022...1,513,604 		JBrowse link
G AFG3L2 AFG3 like matrix AAA peptidase subunit 2 enables IEA
IDA
IBA		 (PMID:19748354), (PMID:22354088), (PMID:28396416), (PMID:29545505), (PMID:29932645), (PMID:31327635), (PMID:37917749), (PMID:38157846) InterPro
UniProt
TreeGrafter
GO_Central		 PMID:19748354 PMID:22354088 PMID:28396416 PMID:29545505 PMID:29932645 More... GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr18:12,328,944...12,377,227
Ensembl chr18:12,328,944...12,377,227 		JBrowse link
G ASTL astacin like metalloendopeptidase enables IEA
IBA		 InterPro
TreeGrafter
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000118 NCBI chr 2:96,122,818...96,138,564
Ensembl chr 2:96,122,818...96,138,502 		JBrowse link
G ATP23 ATP23 metallopeptidase and ATP synthase assembly factor homolog enables IEA InterPro GO_REF:0000002 NCBI chr12:57,941,567...57,959,148
Ensembl chr12:57,906,039...57,959,148 		JBrowse link
G BMP1 bone morphogenetic protein 1 enables IEA
IBA
TAS		 UniProt
GO_Central
InterPro
Reactome
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 Reactome:R-HSA-2002428 Reactome:R-HSA-2002440 Reactome:R-HSA-2022141 NCBI chr 8:22,165,372...22,212,326
Ensembl chr 8:22,165,140...22,212,326 		JBrowse link
G CIROP ciliated left-right organizer metallopeptidase enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr14:23,099,062...23,104,989
Ensembl chr14:23,099,062...23,104,989 		JBrowse link
G CLCA1 chloride channel accessory 1 enables TAS Reactome Reactome:R-HSA-5333671 NCBI chr 1:86,468,927...86,500,259
Ensembl chr 1:86,468,368...86,500,259 		JBrowse link
G CLCA2 chloride channel accessory 2 enables TAS Reactome Reactome:R-HSA-5333671 NCBI chr 1:86,424,171...86,456,553
Ensembl chr 1:86,424,171...86,456,553 		JBrowse link
G CLCA3P chloride channel accessory 3, pseudogene enables TAS Reactome Reactome:R-HSA-5333671 NCBI chr 1:86,634,276...86,655,376
Ensembl chr 1:86,634,276...86,654,745
Ensembl chr 1:86,634,276...86,654,745 		JBrowse link
G CLCA4 chloride channel accessory 4 enables TAS Reactome Reactome:R-HSA-5333671 NCBI chr 1:86,547,078...86,580,754
Ensembl chr 1:86,547,078...86,580,754 		JBrowse link
G ECE1 endothelin converting enzyme 1 enables TAS
IBA
IEA
ISS		 (PMID:8062389) Reactome
GO_Central
UniProt
InterPro
BHF-UCL		 PMID:8062389 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 Reactome:R-HSA-8876868 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572 		JBrowse link
G ECE2 endothelin converting enzyme 2 enables IEA
IBA
TAS
IDA		 (PMID:11718899) InterPro
TreeGrafter
GO_Central
Reactome
UniProt		 PMID:11718899 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-8877620 NCBI chr 3:184,276,022...184,293,031
Ensembl chr 3:184,276,011...184,293,031 		JBrowse link
G ECEL1 endothelin converting enzyme like 1 enables IEA
IBA		 UniProt
TreeGrafter
GO_Central
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:232,479,827...232,487,834
Ensembl chr 2:232,479,827...232,487,834 		JBrowse link
G EEF1AKMT4-ECE2 EEF1AKMT4-ECE2 readthrough enables IDA
IBA
IEA
TAS		 (PMID:11718899) UniProt
GO_Central
InterPro
Reactome		 PMID:11718899 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 Reactome:R-HSA-8877620 NCBI chr 3:184,249,672...184,293,031
Ensembl chr 3:184,249,695...184,293,031 		JBrowse link
G IDE insulin degrading enzyme enables ISO
IEA
IBA
IDA
TAS		 atrial natriuretic peptide cleaved at the Ser25-Phe26 bond
(PMID:17051221), (PMID:17613531)
(PMID:10684867)		 RGD
TreeGrafter
GO_Central
UniProt
InterPro
ARUK-UCL		 PMID:10684867 PMID:15494400 PMID:15749695 PMID:17051221 PMID:17613531 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 RGD:1626704 RGD:1626705 NCBI chr10:92,451,684...92,574,093
Ensembl chr10:92,451,684...92,574,096 		JBrowse link
G KEL Kell metallo-endopeptidase (Kell blood group) enables IDA
IBA
IEA		 (PMID:15769748) HGNC-UCL
GO_Central
TreeGrafter
InterPro		 PMID:15769748 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:142,941,114...142,962,363
Ensembl chr 7:142,941,114...142,962,363 		JBrowse link
G KLK7 kallikrein related peptidase 7 enables TAS Reactome Reactome:R-HSA-3827958 NCBI chr19:50,976,468...50,984,064
Ensembl chr19:50,976,468...50,984,099 		JBrowse link
G LMLN leishmanolysin like peptidase enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr 3:197,960,217...198,043,720
Ensembl chr 3:197,960,200...198,043,720 		JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 enables TAS
IBA
IEA
IDA
EXP		 (PMID:9659902)
(PMID:11163209)		 PINC
GO_Central
TreeGrafter
InterPro
UniProt
Reactome		 PMID:9659902 PMID:11163209 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:21,839,617...21,885,423
Ensembl chr  X:21,839,617...21,885,423 		JBrowse link
G MEP1A meprin A subunit alpha enables IEA
IBA		 UniProt
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000104 NCBI chr 6:46,793,389...46,845,984
Ensembl chr 6:46,793,389...46,839,778 		JBrowse link
G MEP1B meprin A subunit beta enables ISO
IBA
IEA		 RGD
GO_Central
UniProt
InterPro		 PMID:12437103 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 RGD:633322 NCBI chr18:32,190,039...32,220,404
Ensembl chr18:32,185,069...32,220,404 		JBrowse link
G MIPEP mitochondrial intermediate peptidase enables TAS
IBA
IEA		 (PMID:9073519) PINC
GO_Central
InterPro
UniProt		 PMID:9073519 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 NCBI chr13:23,730,189...23,889,400
Ensembl chr13:23,730,189...23,889,400 		JBrowse link
G MME membrane metalloendopeptidase enables IMP
IEA
IBA
IDA		 (PMID:2521388)
(PMID:15283675), (PMID:27588448), (PMID:6208535), (PMID:6349683)		 UniProt
TreeGrafter
GO_Central
InterPro		 PMID:2521388 PMID:6208535 PMID:6349683 PMID:15283675 PMID:27588448 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704 		JBrowse link
G MMEL1 membrane metalloendopeptidase like 1 enables ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter
InterPro
UniProt		 PMID:11964170 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 RGD:2314417 NCBI chr 1:2,590,639...2,633,016
Ensembl chr 1:2,590,639...2,633,016 		JBrowse link
G MMP1 matrix metallopeptidase 1 enables IDA
IEA
IBA
TAS		 (PMID:9920899)
(PMID:3027129)		 BHF-UCL
TreeGrafter
GO_Central
UniProt
PINC
InterPro		 PMID:3027129 PMID:9920899 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-1454757 Reactome:R-HSA-1454822 Reactome:R-HSA-1474213 Reactome:R-HSA-1564120 Reactome:R-HSA-1564169 Reactome:R-HSA-3791149 Reactome:R-HSA-381435 Reactome:R-NUL-2484859 Reactome:R-NUL-2484869 Reactome:R-NUL-3814821 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP10 matrix metallopeptidase 10 enables IEA
IBA
TAS		 (PMID:2844164) UniProt
GO_Central
Reactome
InterPro		 PMID:2844164 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 Reactome:R-HSA-1564142 Reactome:R-HSA-1564164 Reactome:R-HSA-3791149 Reactome:R-NUL-2485115 Reactome:R-NUL-2533858 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628 		JBrowse link
G MMP11 matrix metallopeptidase 11 enables TAS
IBA
IEA		 (PMID:7746327) Reactome
GO_Central
TreeGrafter
InterPro		 PMID:7746327 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-1564112 NCBI chr22:23,772,849...23,784,316
Ensembl chr22:23,768,226...23,784,316 		JBrowse link
G MMP12 matrix metallopeptidase 12 enables TAS
IBA
IDA
IEA
IMP		 (PMID:8226919)
(PMID:24784232)
(PMID:19932771)		 Reactome
GO_Central
CAFA
InterPro		 PMID:8226919 PMID:19932771 PMID:24784232 GO_REF:0000002 GO_REF:0000033 Reactome:R-HSA-1454757 Reactome:R-HSA-1564142 Reactome:R-HSA-2168046 Reactome:R-HSA-2485148 Reactome:R-NUL-3814821 NCBI chr11:102,862,736...102,874,982
Ensembl chr11:102,862,736...102,874,982 		JBrowse link
G MMP13 matrix metallopeptidase 13 enables ISO
IBA
IEA
TAS
IDA		 (PMID:8609233)
(PMID:8576151), (PMID:9065415)		 RGD
GO_Central
TreeGrafter
InterPro
Reactome
UniProt
Ensembl		 PMID:8576151 PMID:8609233 PMID:8910479 PMID:9065415 PMID:17941091 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:2296055 RGD:2298541 Reactome:R-HSA-1454757 Reactome:R-HSA-1454822 Reactome:R-HSA-1474213 Reactome:R-HSA-2485148 Reactome:R-HSA-3791149 Reactome:R-HSA-8942302 Reactome:R-NUL-2482219 Reactome:R-NUL-2484854 Reactome:R-NUL-2484948 Reactome:R-NUL-3814821 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732 		JBrowse link
G MMP14 matrix metallopeptidase 14 enables IEA
IBA
IDA
ISS
TAS		 (PMID:35177851), (PMID:8015608)
(PMID:8015608)		 Ensembl
GO_Central
UniProt
TreeGrafter
InterPro
Reactome		 PMID:8015608 PMID:35177851 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 Reactome:R-HSA-1474210 Reactome:R-HSA-2514790 Reactome:R-HSA-2514831 Reactome:R-HSA-2533950 Reactome:R-HSA-2534240 Reactome:R-HSA-3791155 Reactome:R-HSA-3828025 Reactome:R-NUL-2473583 Reactome:R-NUL-2473590 Reactome:R-NUL-2533890 Reactome:R-NUL-2533964 NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041 		JBrowse link
G MMP15 matrix metallopeptidase 15 enables TAS
IEA
IBA		 (PMID:7649159) Reactome
TreeGrafter
GO_Central
InterPro		 PMID:7649159 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-2473584 Reactome:R-HSA-2473594 Reactome:R-HSA-2473596 Reactome:R-HSA-2534240 Reactome:R-NUL-2533964 NCBI chr16:58,025,754...58,046,901
Ensembl chr16:58,025,754...58,046,901 		JBrowse link
G MMP16 matrix metallopeptidase 16 enables IDA
IBA
IEA
TAS		 (PMID:27229514)
(PMID:7559440)		 ParkinsonsUK-UCL
GO_Central
InterPro
PINC		 PMID:7559440 PMID:27229514 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:88,032,011...88,327,483
Ensembl chr 8:88,032,011...88,328,025 		JBrowse link
G MMP17 matrix metallopeptidase 17 enables TAS
IBA
IEA		 (PMID:8640782) PINC
GO_Central
TreeGrafter
InterPro		 PMID:8640782 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr12:131,828,393...131,851,771
Ensembl chr12:131,828,393...131,851,783 		JBrowse link
G MMP19 matrix metallopeptidase 19 enables EXP
IBA
IEA
TAS		 (PMID:10809722) Reactome
GO_Central
InterPro		 PMID:10809722 GO_REF:0000002 GO_REF:0000033 Reactome:R-HSA-3791149 NCBI chr12:55,835,433...55,842,936
Ensembl chr12:55,835,433...55,842,966 		JBrowse link
G MMP2 matrix metallopeptidase 2 enables IEA
IBA
TAS		 (PMID:2834383) Ensembl
GO_Central
InterPro
UniProt
Reactome		 PMID:2834383 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 Reactome:R-HSA-1454757 Reactome:R-HSA-1454822 Reactome:R-HSA-1564112 Reactome:R-HSA-1564120 Reactome:R-HSA-1564142 Reactome:R-HSA-1564164 Reactome:R-HSA-2485148 Reactome:R-HSA-2534248 Reactome:R-HSA-3791149 Reactome:R-HSA-381435 Reactome:R-HSA-8940554 Reactome:R-HSA-8943959 Reactome:R-NUL-2484859 Reactome:R-NUL-2484869 Reactome:R-NUL-3814821 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP20 matrix metallopeptidase 20 enables TAS
IEA
IBA
IDA		 (PMID:9398237) PINC
TreeGrafter
GO_Central
InterPro
CACAO		 PMID:9398237 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr11:102,576,832...102,625,332
Ensembl chr11:102,576,832...102,625,332 		JBrowse link
G MMP21 matrix metallopeptidase 21 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:125,766,453...125,775,821
Ensembl chr10:125,753,580...125,775,821 		JBrowse link
G MMP23B matrix metallopeptidase 23B enables NAS
IBA
IEA
IDA		 (PMID:9740677)
(PMID:9988691)		 UniProt
GO_Central
InterPro		 PMID:9740677 PMID:9988691 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:1,632,173...1,634,654
Ensembl chr 1:1,632,163...1,635,263 		JBrowse link
G MMP24 matrix metallopeptidase 24 enables ISS
IBA
IEA
TAS		 (PMID:10363975) UniProt
GO_Central
TreeGrafter
InterPro
Ensembl
PINC		 PMID:10363975 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr20:35,226,690...35,276,998
Ensembl chr20:35,226,690...35,276,998 		JBrowse link
G MMP25 matrix metallopeptidase 25 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr16:3,046,561...3,060,726
Ensembl chr16:3,046,062...3,060,726 		JBrowse link
G MMP26 matrix metallopeptidase 26 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr11:4,704,784...4,992,429
Ensembl chr11:4,704,784...4,992,431 		JBrowse link
G MMP27 matrix metallopeptidase 27 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr11:102,691,487...102,705,769
Ensembl chr11:102,691,487...102,705,769 		JBrowse link
G MMP28 matrix metallopeptidase 28 enables IEA
IBA
TAS		 (PMID:11121398), (PMID:11255011) InterPro
GO_Central
UniProt		 PMID:11121398 PMID:11255011 GO_REF:0000002 GO_REF:0000033 NCBI chr17:35,756,249...35,795,641
Ensembl chr17:35,756,249...35,795,707 		JBrowse link
G MMP3 matrix metallopeptidase 3 enables IEA
IBA
TAS		 (PMID:3360803) UniProt
GO_Central
InterPro
Reactome		 PMID:3360803 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 Reactome:R-HSA-1454757 Reactome:R-HSA-1564120 Reactome:R-HSA-1564142 Reactome:R-HSA-2534248 Reactome:R-HSA-3791149 Reactome:R-HSA-4086205 Reactome:R-NUL-2482219 Reactome:R-NUL-2484854 Reactome:R-NUL-2484859 Reactome:R-NUL-3814821 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609 		JBrowse link
G MMP7 matrix metallopeptidase 7 enables IEA
IBA
TAS		 (PMID:1497627) UniProt
TreeGrafter
GO_Central
InterPro
Reactome		 PMID:1497627 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-1454757 Reactome:R-HSA-1564142 Reactome:R-HSA-2534248 Reactome:R-HSA-3791149 Reactome:R-HSA-4086205 Reactome:R-HSA-8940561 Reactome:R-NUL-3814821 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750 		JBrowse link
G MMP8 matrix metallopeptidase 8 enables TAS
IBA
IEA		 Reactome
GO_Central
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-1454757 Reactome:R-HSA-1454822 Reactome:R-HSA-1474213 Reactome:R-HSA-3791149 NCBI chr11:102,711,796...102,724,954
Ensembl chr11:102,711,796...102,727,050 		JBrowse link
G MMP9 matrix metallopeptidase 9 enables IEA
IBA
IDA
TAS		 (PMID:16192646), (PMID:24164424), (PMID:2551898), (PMID:9789069) Ensembl
GO_Central
TreeGrafter
InterPro
MGI
UniProt
Reactome		 PMID:2551898 PMID:9789069 PMID:16192646 PMID:24164424 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 Reactome:R-HSA-1454757 Reactome:R-HSA-1474213 Reactome:R-HSA-1564112 Reactome:R-HSA-1564142 Reactome:R-HSA-1564164 Reactome:R-HSA-2485148 Reactome:R-HSA-3827958 Reactome:R-HSA-8943959 Reactome:R-NUL-2484859 Reactome:R-NUL-2484927 Reactome:R-NUL-2484948 Reactome:R-NUL-3814821 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G NLN neurolysin enables ISO
IBA
IEA
TAS		 RGD
GO_Central
TreeGrafter
Reactome
InterPro		 PMID:7836437 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 RGD:9831155 Reactome:R-HSA-8940959 NCBI chr 5:65,722,205...65,829,283
Ensembl chr 5:65,722,205...65,871,725 		JBrowse link
G NRDC nardilysin convertase enables IEA
NAS		 (PMID:9581555) UniProt
TreeGrafter
InterPro		 PMID:9581555 GO_REF:0000002 GO_REF:0000003 GO_REF:0000118 NCBI chr 1:51,789,210...51,878,727
Ensembl chr 1:51,789,191...51,878,805 		JBrowse link
G OMA1 OMA1 zinc metallopeptidase enables IDA
IBA
IEA
IMP		 (PMID:25275009), (PMID:32132706), (PMID:32132707)
(PMID:20038677)		 UniProt
GO_Central
InterPro
Ensembl		 PMID:20038677 PMID:25275009 PMID:32132706 PMID:32132707 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:58,480,719...58,546,726
Ensembl chr 1:58,415,384...58,546,802 		JBrowse link
G PAPLN papilin, proteoglycan like sulfated glycoprotein enables IEA TreeGrafter GO_REF:0000118 NCBI chr14:73,235,805...73,274,623
Ensembl chr14:73,237,497...73,274,640 		JBrowse link
G PAPPA pappalysin 1 enables EXP
IEA
IBA
TAS		 (PMID:11513734) Reactome
TreeGrafter
GO_Central		 PMID:11513734 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-381537 NCBI chr 9:116,153,791...116,402,321
Ensembl chr 9:116,153,791...116,402,321 		JBrowse link
G PAPPA2 pappalysin 2 enables EXP
IBA
TAS		 (PMID:11513734) Reactome
GO_Central		 PMID:11513734 GO_REF:0000033 Reactome:R-HSA-381537 NCBI chr 1:176,463,175...176,845,601
Ensembl chr 1:176,463,171...176,845,601 		JBrowse link
G PHEX phosphate regulating endopeptidase X-linked enables IEA
IBA
TAS		 (PMID:9593714) InterPro
GO_Central
TreeGrafter
PINC		 PMID:9593714 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr  X:22,032,325...22,251,310
Ensembl chr  X:22,032,325...22,494,713 		JBrowse link
G PITRM1 pitrilysin metallopeptidase 1 enables IMP
IEA
IBA
IDA		 (PMID:16849325), (PMID:24931469)
(PMID:10360838), (PMID:19196155)		 UniProt
TreeGrafter
GO_Central		 PMID:10360838 PMID:16849325 PMID:19196155 PMID:24931469 GO_REF:0000033 GO_REF:0000118 NCBI chr10:3,137,727...3,172,841
Ensembl chr10:3,137,728...3,172,841 		JBrowse link
G PMPCA peptidase, mitochondrial processing subunit alpha enables IEA InterPro GO_REF:0000002 NCBI chr 9:136,410,658...136,423,761
Ensembl chr 9:136,410,630...136,427,992 		JBrowse link
G PMPCB peptidase, mitochondrial processing subunit beta enables TAS
IBA
IEA
IDA		 (PMID:22354088) Reactome
GO_Central
TreeGrafter
InterPro
UniProt		 PMID:22354088 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-8949649 NCBI chr 7:103,297,435...103,347,542
Ensembl chr 7:103,297,407...103,331,818 		JBrowse link
G PRSS2 serine protease 2 enables TAS Reactome Reactome:R-HSA-1454822 NCBI chr 7:142,770,970...142,774,560
Ensembl chr 7:142,760,398...142,774,564 		JBrowse link
G RCE1 Ras converting CAAX endopeptidase 1 enables IEA
IBA		 InterPro
GO_Central
TreeGrafter		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr11:66,843,441...66,846,552
Ensembl chr11:66,842,835...66,846,552 		JBrowse link
G SAT1 spermidine/spermine N1-acetyltransferase 1 enables IEA InterPro GO_REF:0000002 NCBI chr  X:23,783,173...23,786,210
Ensembl chr  X:23,783,173...23,786,210 		JBrowse link
G SPG7 SPG7 matrix AAA peptidase subunit, paraplegin enables IEA InterPro GO_REF:0000002 NCBI chr16:89,490,970...89,499,282
Ensembl chr16:89,490,719...89,557,766 		JBrowse link
G SPG7 SPG7 matrix AAA peptidase subunit, paraplegin enables IEA
IDA
IBA		 (PMID:11549317), (PMID:28396416), (PMID:31097542) InterPro
UniProt
GO_Central		 PMID:11549317 PMID:28396416 PMID:31097542 GO_REF:0000002 GO_REF:0000033 NCBI chr16:89,508,388...89,557,768
Ensembl chr16:89,490,719...89,557,766 		JBrowse link
G SPRTN SprT-like N-terminal domain enables IEA
IDA		 (PMID:27852435), (PMID:27871365), (PMID:27871366), (PMID:32649882), (PMID:36608669) InterPro
UniProt		 PMID:27852435 PMID:27871365 PMID:27871366 PMID:32649882 PMID:36608669 GO_REF:0000002 NCBI chr 1:231,338,293...231,355,023
Ensembl chr 1:231,337,104...231,355,023 		JBrowse link
G THOP1 thimet oligopeptidase 1 enables IEA
IBA
TAS		 (PMID:7639763) InterPro
GO_Central
TreeGrafter
PINC		 PMID:7639763 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-8940641 NCBI chr19:2,785,503...2,815,807
Ensembl chr19:2,785,503...2,815,807 		JBrowse link
G TLL1 tolloid like 1 enables IEA
IBA
TAS		 UniProt
GO_Central
InterPro
Reactome		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 Reactome:R-HSA-2002440 Reactome:R-HSA-2022141 NCBI chr 4:165,873,237...166,104,457
Ensembl chr 4:165,873,237...166,104,457 		JBrowse link
G TLL2 tolloid like 2 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:96,364,608...96,513,926
Ensembl chr10:96,364,608...96,513,926 		JBrowse link
G TMPRSS6 transmembrane serine protease 6 enables TAS Reactome Reactome:R-HSA-1474210 Reactome:R-HSA-2514790 Reactome:R-HSA-2514831 Reactome:R-HSA-2533950 Reactome:R-HSA-3791155 Reactome:R-HSA-3828025 Reactome:R-NUL-2473583 Reactome:R-NUL-2473590 Reactome:R-NUL-2533890 NCBI chr22:37,065,436...37,110,536
Ensembl chr22:37,065,436...37,109,713 		JBrowse link
G TRABD2A TraB domain containing 2A enables IDA
IBA
IEA
ISS		 (PMID:22726442) UniProt
GO_Central
ParkinsonsUK-UCL		 PMID:22726442 GO_REF:0000033 GO_REF:0000104 NCBI chr 2:84,821,666...84,881,084
Ensembl chr 2:84,821,650...84,907,008 		JBrowse link
G TRABD2B TraB domain containing 2B enables IDA
IBA		 (PMID:22726442) ParkinsonsUK-UCL
GO_Central		 PMID:22726442 GO_REF:0000033 NCBI chr 1:47,760,528...47,997,385
Ensembl chr 1:47,760,528...47,997,385 		JBrowse link
G UQCRC2 ubiquinol-cytochrome c reductase core protein 2 enables IEA InterPro GO_REF:0000002 NCBI chr16:21,953,361...21,983,660
Ensembl chr16:21,953,288...21,983,660 		JBrowse link
G YBEY ybeY metalloendoribonuclease enables IEA InterPro GO_REF:0000002 NCBI chr21:46,286,342...46,313,225
Ensembl chr21:46,286,342...46,297,751 		JBrowse link
G YME1L1 YME1 like 1 ATPase enables IEA InterPro GO_REF:0000002 NCBI chr10:27,110,111...27,154,384
Ensembl chr10:27,110,111...27,155,266 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 enables IEA
IBA		 UniProt
GO_Central
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr 1:40,258,236...40,294,180
Ensembl chr 1:40,258,041...40,294,180 		JBrowse link
metalloendopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM10 ADAM metallopeptidase domain 10 enables ISS
IBA
IEA
IMP		 (PMID:28164773) ARUK-UCL
GO_Central
TreeGrafter
UniProt		 PMID:28164773 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr15:58,588,809...58,749,707
Ensembl chr15:58,588,809...58,749,791 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 enables IDA (PMID:9774383) ARUK-UCL PMID:9774383 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732 		JBrowse link
G ADAM19 ADAM metallopeptidase domain 19 enables IMP (PMID:17112471) ARUK-UCL PMID:17112471 NCBI chr 5:157,477,304...157,575,775
Ensembl chr 5:157,395,534...157,575,775 		JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 enables IDA (PMID:12054541) ARUK-UCL PMID:12054541 NCBI chr 8:38,996,973...39,105,261
Ensembl chr 8:38,996,754...39,105,445 		JBrowse link
metalloexopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPEP1 dipeptidase 1 enables TAS (PMID:2303490) UniProt PMID:2303490 NCBI chr16:89,613,308...89,641,540
Ensembl chr16:89,613,308...89,638,456 		JBrowse link
G DPP3 dipeptidyl peptidase 3 enables IEA InterPro GO_REF:0000002 NCBI chr11:66,480,434...66,509,657
Ensembl chr11:66,480,013...66,509,657 		JBrowse link
G ERAP1 endoplasmic reticulum aminopeptidase 1 enables IDA (PMID:10220586) UniProt PMID:10220586 NCBI chr 5:96,760,813...96,935,854
Ensembl chr 5:96,760,810...96,808,100 		JBrowse link
G ERMP1 endoplasmic reticulum metallopeptidase 1 enables IEA InterPro GO_REF:0000002 NCBI chr 9:5,784,572...5,867,091
Ensembl chr 9:5,749,832...5,879,537 		JBrowse link
G LAP3 leucine aminopeptidase 3 enables NAS (PMID:1908238) UniProt PMID:1908238 NCBI chr 4:17,577,198...17,607,970
Ensembl chr 4:17,577,198...17,607,972 		JBrowse link
G METAP1 methionyl aminopeptidase 1 enables TAS (PMID:16386852) UniProt PMID:16386852 NCBI chr 4:98,995,721...99,062,809
Ensembl chr 4:98,995,659...99,062,809 		JBrowse link
G METAP1D methionyl aminopeptidase type 1D, mitochondrial enables TAS (PMID:14532271) UniProt PMID:14532271 NCBI chr 2:171,999,953...172,082,430
Ensembl chr 2:171,999,943...172,082,430 		JBrowse link
G METAP2 methionyl aminopeptidase 2 enables IDA
IEA
IBA		 (PMID:8858118) UniProt
TreeGrafter
GO_Central		 PMID:8858118 GO_REF:0000033 GO_REF:0000118 NCBI chr12:95,474,152...95,515,839
Ensembl chr12:95,473,520...95,515,839 		JBrowse link
G NUDT16 nudix hydrolase 16 enables IDA (PMID:21337011) UniProt PMID:21337011 NCBI chr 3:131,381,671...131,388,830
Ensembl chr 3:131,381,671...131,388,830 		JBrowse link
G RNPEP arginyl aminopeptidase enables NAS (PMID:12119107) UniProt PMID:12119107 NCBI chr 1:201,982,648...202,006,143
Ensembl chr 1:201,982,372...202,006,147 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 enables TAS (PMID:10373325) PINC PMID:10373325 NCBI chr 1:40,258,236...40,294,180
Ensembl chr 1:40,258,041...40,294,180 		JBrowse link
tubulin-tyrosine carboxypeptidase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MATCAP1 microtubule associated tyrosine carboxypeptidase 1 enables IDA (PMID:35482892) UniProt PMID:35482892 NCBI chr16:67,175,599...67,183,963
Ensembl chr16:67,175,599...67,184,040 		JBrowse link
G VASH1 vasohibin 1 enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr14:76,761,468...76,783,015
Ensembl chr14:76,761,468...76,783,015 		JBrowse link
G VASH2 vasohibin 2 enables IEA UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:212,950,541...212,991,585
Ensembl chr 1:212,950,520...212,992,037 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19488
    catalytic activity 5987
      catalytic activity, acting on a protein 2451
        peptidase activity 652
          metallopeptidase activity 195
            metal-dependent deNEDDylase activity 0
            metal-dependent deubiquitinase activity 12
            metalloendopeptidase activity + 116
            metalloexopeptidase activity + 71
paths to the root