Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: COPS5 (COP9 signalosome subunit 5) Homo sapiens
Symbol: COPS5
Name: COP9 signalosome subunit 5
Description: Exhibits metallopeptidase activity and thiol-dependent ubiquitin-specific protease activity. Involved in several processes, including protein modification by small protein removal; regulation of cellular response to stress; and regulation of transcription, DNA-templated. Localizes to several cellular components, including the nucleus; perinuclear region of cytoplasm; and synaptic vesicle. Colocalizes with the chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 38 kDa Mov34 homolog; COP9 constitutive photomorphogenic homolog subunit 5; COP9 signalosome complex subunit 5; CSN5; JAB1; jun activation domain-binding protein 1; MGC3149; MOV-34; SGN5; signalosome subunit 5; testis secretory sperm-binding protein Li 231m
Mus musculus (house mouse) : Cops5 (COP9 signalosome subunit 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cops5 (COP9 signalosome subunit 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cops5 (COP9 signalosome subunit 5)
Pan paniscus (bonobo/pygmy chimpanzee) : COPS5 (COP9 signalosome subunit 5)
Canis lupus familiaris (dog) : COPS5 (COP9 signalosome subunit 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cops5 (COP9 signalosome subunit 5)
Sus scrofa (pig) : COPS5 (COP9 signalosome subunit 5)
Chlorocebus sabaeus (green monkey) : COPS5 (COP9 signalosome subunit 5)
Heterocephalus glaber (naked mole-rat) : Cops5 (COP9 signalosome subunit 5)
more info ...
Related Pseudogenes: COPS5P1   COPS5P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl867,043,079 - 67,083,783 (-)Ensembl
GRCh38867,043,079 - 67,062,133 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37867,955,314 - 67,974,562 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36868,117,868 - 68,137,116 (-)NCBINCBI36hg18NCBI36
Build 34868,117,869 - 68,137,116NCBI
Celera863,948,870 - 63,967,877 (-)NCBI
Cytogenetic Map8q13.1NCBI
HuRef863,447,901 - 63,467,140 (-)NCBIHuRef
CHM1_1868,010,363 - 68,029,584 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on COPS5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321125
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.