LVRN (laeverin) - Rat Genome Database

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Gene: LVRN (laeverin) Homo sapiens
Analyze
Symbol: LVRN
Name: laeverin
RGD ID: 1604505
HGNC Page HGNC:26904
Description: Predicted to enable metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to be active in cytoplasm; extracellular space; and membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: aminopeptidase Q; AP-Q; APQ; AQPEP; CHL2 antigen; FLJ90650; MGC125378; MGC125379; TAQPEP
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385115,962,475 - 116,027,606 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5115,962,454 - 116,027,619 (+)EnsemblGRCh38hg38GRCh38
GRCh375115,298,172 - 115,363,303 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365115,326,170 - 115,391,199 (+)NCBINCBI36Build 36hg18NCBI36
Celera5111,246,534 - 111,311,673 (+)NCBICelera
Cytogenetic Map5q23.1NCBI
HuRef5110,478,890 - 110,544,021 (+)NCBIHuRef
CHM1_15114,730,769 - 114,796,042 (+)NCBICHM1_1
T2T-CHM13v2.05116,474,883 - 116,539,987 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)
extracellular space  (IBA)
membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Autism  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:14706636   PMID:15489334   PMID:15897020   PMID:16804865   PMID:17525158   PMID:19578876   PMID:19819873   PMID:20379614   PMID:21212512   PMID:21873635  
PMID:22402206   PMID:24623722   PMID:24959655   PMID:25367360   PMID:25378659   PMID:25416956   PMID:29355889   PMID:29681208   PMID:33355358   PMID:33982062  


Genomics

Comparative Map Data
LVRN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385115,962,475 - 116,027,606 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5115,962,454 - 116,027,619 (+)EnsemblGRCh38hg38GRCh38
GRCh375115,298,172 - 115,363,303 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365115,326,170 - 115,391,199 (+)NCBINCBI36Build 36hg18NCBI36
Celera5111,246,534 - 111,311,673 (+)NCBICelera
Cytogenetic Map5q23.1NCBI
HuRef5110,478,890 - 110,544,021 (+)NCBIHuRef
CHM1_15114,730,769 - 114,796,042 (+)NCBICHM1_1
T2T-CHM13v2.05116,474,883 - 116,539,987 (+)NCBIT2T-CHM13v2.0
Lvrn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391846,983,106 - 47,040,313 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1846,983,105 - 47,040,309 (+)EnsemblGRCm39 Ensembl
GRCm381846,848,826 - 46,907,246 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1846,850,038 - 46,907,242 (+)EnsemblGRCm38mm10GRCm38
MGSCv371847,009,693 - 47,065,100 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361846,975,376 - 47,030,777 (+)NCBIMGSCv36mm8
Celera1848,207,861 - 48,266,898 (+)NCBICelera
Cytogenetic Map18CNCBI
cM Map1824.84NCBI
Lvrn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81841,752,788 - 41,861,830 (+)NCBIGRCr8
mRatBN7.21839,606,047 - 39,675,247 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1839,607,722 - 39,675,165 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01840,858,828 - 40,957,472 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1840,883,224 - 40,953,864 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01840,527,597 - 40,601,604 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41841,091,421 - 41,159,543 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1837,857,623 - 37,926,884 (+)NCBICelera
Cytogenetic Map18q11NCBI
Lvrn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540835,761,884 - 35,822,443 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540835,761,737 - 35,823,550 (+)NCBIChiLan1.0ChiLan1.0
LVRN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24111,206,823 - 111,277,019 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15109,360,445 - 109,426,347 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05111,316,857 - 111,381,594 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15117,113,730 - 117,178,853 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5117,113,730 - 117,178,849 (+)Ensemblpanpan1.1panPan2
LVRN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1115,684,244 - 5,750,792 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl115,684,568 - 5,776,455 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha115,835,040 - 5,901,425 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0115,676,282 - 5,742,693 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl115,676,037 - 5,742,090 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1115,625,222 - 5,691,572 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0115,702,629 - 5,769,024 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0115,954,851 - 6,019,641 (+)NCBIUU_Cfam_GSD_1.0
Lvrn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213128,423,731 - 128,506,695 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367421,124,524 - 1,206,008 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367421,124,286 - 1,207,439 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LVRN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2120,117,653 - 120,193,713 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12120,117,584 - 120,193,728 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22125,024,882 - 125,099,597 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LVRN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12319,243,593 - 19,317,447 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2319,244,673 - 19,321,208 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603459,087,464 - 59,166,687 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lvrn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247335,829,438 - 5,896,796 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247335,828,615 - 5,896,954 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LVRN
48 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 5q21.3-33.2(chr5:106619588-156124387)x1 copy number loss See cases [RCV000053524] Chr5:106619588..156124387 [GRCh38]
Chr5:105955289..155551397 [GRCh37]
Chr5:105983188..155483975 [NCBI36]
Chr5:5q21.3-33.2		 pathogenic
NM_173800.4(LVRN):c.1486G>A (p.Glu496Lys) single nucleotide variant Malignant melanoma [RCV000061098] Chr5:115999873 [GRCh38]
Chr5:115335570 [GRCh37]
Chr5:115363469 [NCBI36]
Chr5:5q23.1		 not provided
NM_173800.4(LVRN):c.1800T>C (p.Asn600=) single nucleotide variant Malignant melanoma [RCV000061099] Chr5:116001219 [GRCh38]
Chr5:115336916 [GRCh37]
Chr5:115364815 [NCBI36]
Chr5:5q23.1		 not provided
GRCh38/hg38 5q21.3-23.1(chr5:108585264-116815075)x1 copy number loss See cases [RCV000133813] Chr5:108585264..116815075 [GRCh38]
Chr5:107920965..116150771 [GRCh37]
Chr5:107948864..116178670 [NCBI36]
Chr5:5q21.3-23.1		 pathogenic
GRCh38/hg38 5q22.3-23.2(chr5:114707561-126507744)x1 copy number loss See cases [RCV000134895] Chr5:114707561..126507744 [GRCh38]
Chr5:114043258..125843436 [GRCh37]
Chr5:114071157..125871335 [NCBI36]
Chr5:5q22.3-23.2		 pathogenic
GRCh38/hg38 5q21.3-23.1(chr5:107002209-118025316)x1 copy number loss See cases [RCV000135699] Chr5:107002209..118025316 [GRCh38]
Chr5:106337910..117361011 [GRCh37]
Chr5:106365809..117388910 [NCBI36]
Chr5:5q21.3-23.1		 pathogenic
GRCh38/hg38 5q22.1-23.2(chr5:111463016-127193038)x1 copy number loss See cases [RCV000135549] Chr5:111463016..127193038 [GRCh38]
Chr5:110798714..126528730 [GRCh37]
Chr5:110826613..126556629 [NCBI36]
Chr5:5q22.1-23.2		 pathogenic
GRCh38/hg38 5q22.1-23.3(chr5:110687442-130103838)x1 copy number loss See cases [RCV000139235] Chr5:110687442..130103838 [GRCh38]
Chr5:110023143..129439531 [GRCh37]
Chr5:110051042..129467430 [NCBI36]
Chr5:5q22.1-23.3		 pathogenic|uncertain significance
GRCh38/hg38 5q14.3-23.3(chr5:90374606-128076423)x1 copy number loss See cases [RCV000139893] Chr5:90374606..128076423 [GRCh38]
Chr5:89670423..127412115 [GRCh37]
Chr5:89706179..127440014 [NCBI36]
Chr5:5q14.3-23.3		 pathogenic
GRCh38/hg38 5q14.3-23.1(chr5:92899734-119614119)x1 copy number loss See cases [RCV000141252] Chr5:92899734..119614119 [GRCh38]
Chr5:92235441..118949814 [GRCh37]
Chr5:92261197..118977713 [NCBI36]
Chr5:5q14.3-23.1		 pathogenic
GRCh38/hg38 5q22.2-23.1(chr5:112323517-117773507)x1 copy number loss See cases [RCV000140791] Chr5:112323517..117773507 [GRCh38]
Chr5:111659214..117109202 [GRCh37]
Chr5:111687113..117137101 [NCBI36]
Chr5:5q22.2-23.1		 pathogenic
GRCh38/hg38 5q21.3-23.2(chr5:108308463-125777797)x1 copy number loss See cases [RCV000143326] Chr5:108308463..125777797 [GRCh38]
Chr5:107644164..125113490 [GRCh37]
Chr5:107672063..125141389 [NCBI36]
Chr5:5q21.3-23.2		 pathogenic
GRCh38/hg38 5q14.3-31.1(chr5:91411708-131319563)x1 copy number loss See cases [RCV000143746] Chr5:91411708..131319563 [GRCh38]
Chr5:90707525..130655256 [GRCh37]
Chr5:90743281..130683155 [NCBI36]
Chr5:5q14.3-31.1		 pathogenic
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3 copy number gain not provided [RCV000487658] Chr5:94844077..178830410 [GRCh37]
Chr5:5q15-35.3		 likely benign
GRCh37/hg19 5q22.1-23.2(chr5:110407606-122522885)x1 copy number loss See cases [RCV000446959] Chr5:110407606..122522885 [GRCh37]
Chr5:5q22.1-23.2		 pathogenic
GRCh37/hg19 5q21.1-23.2(chr5:100607918-125900735)x1 copy number loss See cases [RCV000445968] Chr5:100607918..125900735 [GRCh37]
Chr5:5q21.1-23.2		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3 copy number gain See cases [RCV000448245] Chr5:106716357..180687338 [GRCh37]
Chr5:5q21.3-35.3		 pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
NC_000005.9:g.(?_86400000)_(154000000_?)del deletion Familial adenomatous polyposis 1 [RCV002231249]|Hereditary cancer-predisposing syndrome [RCV000554476] Chr5:86400000..154000000 [GRCh37]
Chr5:5q14.3-33.2		 pathogenic
NM_173800.5(LVRN):c.605A>G (p.Tyr202Cys) single nucleotide variant Inborn genetic diseases [RCV003242909] Chr5:115963222 [GRCh38]
Chr5:115298919 [GRCh37]
Chr5:5q23.1		 uncertain significance
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3		 pathogenic
Single allele duplication Autism [RCV000754292] Chr5:114046360..118610426 [GRCh38]
Chr5:5q22.3-23.1		 likely pathogenic
GRCh37/hg19 5q23.1(chr5:115229725-115450657)x3 copy number gain not provided [RCV000745101] Chr5:115229725..115450657 [GRCh37]
Chr5:5q23.1		 benign
GRCh37/hg19 5q23.1(chr5:115236690-115453671)x3 copy number gain not provided [RCV000745102] Chr5:115236690..115453671 [GRCh37]
Chr5:5q23.1		 benign
GRCh37/hg19 5q23.1(chr5:115322822-115517399)x3 copy number gain not provided [RCV000745103] Chr5:115322822..115517399 [GRCh37]
Chr5:5q23.1		 benign
NM_173800.5(LVRN):c.1828T>C (p.Trp610Arg) single nucleotide variant Inborn genetic diseases [RCV003268042] Chr5:116002842 [GRCh38]
Chr5:115338539 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.2514G>A (p.Glu838=) single nucleotide variant not provided [RCV000969202] Chr5:116015315 [GRCh38]
Chr5:115351012 [GRCh37]
Chr5:5q23.1		 benign
NM_173800.5(LVRN):c.2806G>A (p.Val936Ile) single nucleotide variant not provided [RCV000959593] Chr5:116022440 [GRCh38]
Chr5:115358137 [GRCh37]
Chr5:5q23.1		 benign
NM_173800.5(LVRN):c.2533A>G (p.Thr845Ala) single nucleotide variant Inborn genetic diseases [RCV003266898] Chr5:116015334 [GRCh38]
Chr5:115351031 [GRCh37]
Chr5:5q23.1		 uncertain significance
Single allele deletion Neurodevelopmental disorder [RCV000787436] Chr5:14685137..149511942 [GRCh37]
Chr5:5p15.2-q32		 uncertain significance
GRCh37/hg19 5q14.3-23.3(chr5:89949118-129317455)x3 copy number gain not provided [RCV000849289] Chr5:89949118..129317455 [GRCh37]
Chr5:5q14.3-23.3		 pathogenic
GRCh37/hg19 5q21.3-23.1(chr5:108304806-121335239)x1 copy number loss not provided [RCV000846246] Chr5:108304806..121335239 [GRCh37]
Chr5:5q21.3-23.1		 pathogenic
NM_173800.5(LVRN):c.1521G>A (p.Ala507=) single nucleotide variant not provided [RCV000956304] Chr5:116000438 [GRCh38]
Chr5:115336135 [GRCh37]
Chr5:5q23.1		 benign
GRCh37/hg19 5q22.1-23.1(chr5:111443783-116255660) copy number loss not specified [RCV002053518] Chr5:111443783..116255660 [GRCh37]
Chr5:5q22.1-23.1		 pathogenic
GRCh37/hg19 5q21.1-23.2(chr5:100607918-125900735) copy number loss not specified [RCV002053515] Chr5:100607918..125900735 [GRCh37]
Chr5:5q21.1-23.2		 pathogenic
NM_173800.5(LVRN):c.2705G>A (p.Arg902Gln) single nucleotide variant Inborn genetic diseases [RCV002749462] Chr5:116015714 [GRCh38]
Chr5:115351411 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.757G>A (p.Glu253Lys) single nucleotide variant Inborn genetic diseases [RCV002990707] Chr5:115983348 [GRCh38]
Chr5:115319045 [GRCh37]
Chr5:5q23.1		 uncertain significance
GRCh37/hg19 5q22.2-23.3(chr5:112557391-128106299)x1 copy number loss not provided [RCV002475732] Chr5:112557391..128106299 [GRCh37]
Chr5:5q22.2-23.3		 pathogenic
NM_173800.5(LVRN):c.400A>G (p.Thr134Ala) single nucleotide variant Inborn genetic diseases [RCV002779548] Chr5:115963017 [GRCh38]
Chr5:115298714 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.1798A>G (p.Asn600Asp) single nucleotide variant Inborn genetic diseases [RCV002946400] Chr5:116001217 [GRCh38]
Chr5:115336914 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.1064T>C (p.Leu355Pro) single nucleotide variant Inborn genetic diseases [RCV002782153] Chr5:115987898 [GRCh38]
Chr5:115323595 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.364G>C (p.Ala122Pro) single nucleotide variant Inborn genetic diseases [RCV002822674] Chr5:115962981 [GRCh38]
Chr5:115298678 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.949C>T (p.His317Tyr) single nucleotide variant Inborn genetic diseases [RCV002978715] Chr5:115984680 [GRCh38]
Chr5:115320377 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.559T>C (p.Tyr187His) single nucleotide variant Inborn genetic diseases [RCV002822178] Chr5:115963176 [GRCh38]
Chr5:115298873 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.2057G>A (p.Arg686Lys) single nucleotide variant Inborn genetic diseases [RCV002804295] Chr5:116005931 [GRCh38]
Chr5:115341628 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.2645C>G (p.Ser882Cys) single nucleotide variant Inborn genetic diseases [RCV002668176] Chr5:116015654 [GRCh38]
Chr5:115351351 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.229G>C (p.Glu77Gln) single nucleotide variant Inborn genetic diseases [RCV002698870] Chr5:115962846 [GRCh38]
Chr5:115298543 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.547C>G (p.Leu183Val) single nucleotide variant Inborn genetic diseases [RCV002803047] Chr5:115963164 [GRCh38]
Chr5:115298861 [GRCh37]
Chr5:5q23.1		 likely benign
NM_173800.5(LVRN):c.608A>T (p.Glu203Val) single nucleotide variant Inborn genetic diseases [RCV002788872] Chr5:115963225 [GRCh38]
Chr5:115298922 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.2438A>G (p.His813Arg) single nucleotide variant Inborn genetic diseases [RCV002665347] Chr5:116014515 [GRCh38]
Chr5:115350212 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.182C>G (p.Pro61Arg) single nucleotide variant Inborn genetic diseases [RCV002832302] Chr5:115962799 [GRCh38]
Chr5:115298496 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.811G>C (p.Val271Leu) single nucleotide variant Inborn genetic diseases [RCV002673596] Chr5:115983402 [GRCh38]
Chr5:115319099 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.1051A>G (p.Ile351Val) single nucleotide variant Inborn genetic diseases [RCV002939985] Chr5:115987885 [GRCh38]
Chr5:115323582 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.558A>T (p.Glu186Asp) single nucleotide variant Inborn genetic diseases [RCV002959838] Chr5:115963175 [GRCh38]
Chr5:115298872 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.376C>T (p.Pro126Ser) single nucleotide variant Inborn genetic diseases [RCV002673408] Chr5:115962993 [GRCh38]
Chr5:115298690 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.1950G>C (p.Leu650Phe) single nucleotide variant Inborn genetic diseases [RCV003208364] Chr5:116003293 [GRCh38]
Chr5:115338990 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.995G>A (p.Arg332Gln) single nucleotide variant Inborn genetic diseases [RCV003194234] Chr5:115987829 [GRCh38]
Chr5:115323526 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.37C>G (p.Arg13Gly) single nucleotide variant Inborn genetic diseases [RCV003212086] Chr5:115962654 [GRCh38]
Chr5:115298351 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.899C>T (p.Thr300Met) single nucleotide variant Inborn genetic diseases [RCV003184734] Chr5:115984630 [GRCh38]
Chr5:115320327 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.2371G>A (p.Ala791Thr) single nucleotide variant Inborn genetic diseases [RCV003179269] Chr5:116014448 [GRCh38]
Chr5:115350145 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.11C>A (p.Pro4His) single nucleotide variant Inborn genetic diseases [RCV003265574] Chr5:115962628 [GRCh38]
Chr5:115298325 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.1265T>C (p.Phe422Ser) single nucleotide variant Inborn genetic diseases [RCV003345077] Chr5:115993745 [GRCh38]
Chr5:115329442 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.2690C>T (p.Ser897Leu) single nucleotide variant Inborn genetic diseases [RCV003370697] Chr5:116015699 [GRCh38]
Chr5:115351396 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.179C>A (p.Pro60His) single nucleotide variant Inborn genetic diseases [RCV003384490] Chr5:115962796 [GRCh38]
Chr5:115298493 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.2446A>G (p.Asn816Asp) single nucleotide variant Inborn genetic diseases [RCV003352483] Chr5:116014523 [GRCh38]
Chr5:115350220 [GRCh37]
Chr5:5q23.1		 uncertain significance
NM_173800.5(LVRN):c.1436C>G (p.Thr479Ser) single nucleotide variant Inborn genetic diseases [RCV003383190] Chr5:115999823 [GRCh38]
Chr5:115335520 [GRCh37]
Chr5:5q23.1		 likely benign
NM_173800.5(LVRN):c.2229T>C (p.Asp743=) single nucleotide variant not provided [RCV003429738] Chr5:116010876 [GRCh38]
Chr5:115346573 [GRCh37]
Chr5:5q23.1		 likely benign
NM_173800.5(LVRN):c.525C>G (p.Pro175=) single nucleotide variant not provided [RCV003429737] Chr5:115963142 [GRCh38]
Chr5:115298839 [GRCh37]
Chr5:5q23.1		 likely benign
GRCh37/hg19 5q15-23.2(chr5:93828571-123711334)x1 copy number loss not specified [RCV003986577] Chr5:93828571..123711334 [GRCh37]
Chr5:5q15-23.2		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3264
Count of miRNA genes:845
Interacting mature miRNAs:964
Transcripts:ENST00000357872, ENST00000395528, ENST00000503203, ENST00000503329, ENST00000504467, ENST00000506279, ENST00000512314, ENST00000512413, ENST00000514509, ENST00000515454
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D5S2055  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,296,897 - 115,297,109UniSTSGRCh37
Build 365115,324,796 - 115,325,008RGDNCBI36
Celera5111,245,280 - 111,245,492RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,477,628 - 110,477,848UniSTS
Marshfield Genetic Map5125.91RGD
Marshfield Genetic Map5125.91UniSTS
Genethon Genetic Map5125.6UniSTS
Whitehead-YAC Contig Map5 UniSTS
RH66556  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,301,945 - 115,302,064UniSTSGRCh37
Build 365115,329,844 - 115,329,963RGDNCBI36
Celera5111,250,328 - 111,250,447RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,482,684 - 110,482,803UniSTS
GeneMap99-GB4 RH Map5473.68UniSTS
NCBI RH Map5826.1UniSTS
RH98999  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,362,589 - 115,362,741UniSTSGRCh37
Build 365115,390,488 - 115,390,640RGDNCBI36
Celera5111,310,963 - 111,311,115RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,543,311 - 110,543,463UniSTS
GeneMap99-GB4 RH Map5473.58UniSTS
RH98415  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,363,087 - 115,363,223UniSTSGRCh37
Build 365115,390,986 - 115,391,122RGDNCBI36
Celera5111,311,461 - 111,311,597RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,543,809 - 110,543,945UniSTS
GeneMap99-GB4 RH Map5473.58UniSTS
RH120572  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,338,433 - 115,338,769UniSTSGRCh37
Build 365115,366,332 - 115,366,668RGDNCBI36
Celera5111,286,807 - 111,287,143RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,519,156 - 110,519,492UniSTS
TNG Radiation Hybrid Map553061.0UniSTS
SHGC-151261  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,296,803 - 115,296,993UniSTSGRCh37
Build 365115,324,702 - 115,324,892RGDNCBI36
Celera5111,245,186 - 111,245,376RGD
Cytogenetic Map5q23.1UniSTS
HuRef5110,477,534 - 110,477,724UniSTS
TNG Radiation Hybrid Map553071.0UniSTS
SHGC-152535  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375115,296,861 - 115,297,055UniSTSGRCh37
GRCh375115,296,861 - 115,297,043UniSTSGRCh37
Build 365115,324,760 - 115,324,954RGDNCBI36
Celera5111,245,244 - 111,245,438RGD
Celera5111,245,244 - 111,245,426UniSTS
Cytogenetic Map5q23.1UniSTS
HuRef5110,477,592 - 110,477,798UniSTS
HuRef5110,477,592 - 110,477,796UniSTS
HuRef5110,477,592 - 110,477,774UniSTS
TNG Radiation Hybrid Map195697.0UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 36 11 3 15 470 13 3 7 6 613 11 2
Low 1689 1167 393 125 239 17 2759 1233 679 44 709 430 109 589 2011 3
Below cutoff 619 1582 1140 341 1309 290 1072 935 2990 245 634 1065 60 2 766

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_173800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047416913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047416914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047416915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047416916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047416917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047416918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047416919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054352017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054352018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054352019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054352020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054352021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054352022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC010282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC034236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK027809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK055381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY560010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC036440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC045809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC109022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC109023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX096521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF457980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000357872   ⟹   ENSP00000350541
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5115,962,475 - 116,027,606 (+)Ensembl
RefSeq Acc Id: ENST00000395528   ⟹   ENSP00000378899
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5115,962,494 - 116,027,601 (+)Ensembl
RefSeq Acc Id: ENST00000503203
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5116,014,418 - 116,020,115 (+)Ensembl
RefSeq Acc Id: ENST00000503329   ⟹   ENSP00000427418
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5115,995,377 - 116,027,619 (+)Ensembl
RefSeq Acc Id: ENST00000504467   ⟹   ENSP00000423604
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5115,962,454 - 116,026,416 (+)Ensembl
RefSeq Acc Id: ENST00000506279
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5116,022,181 - 116,026,230 (+)Ensembl
RefSeq Acc Id: ENST00000512314   ⟹   ENSP00000427500
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5115,995,397 - 116,026,410 (+)Ensembl
RefSeq Acc Id: ENST00000512413
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5116,021,027 - 116,027,603 (+)Ensembl
RefSeq Acc Id: ENST00000514509   ⟹   ENSP00000427574
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5115,995,377 - 116,026,420 (+)Ensembl
RefSeq Acc Id: ENST00000515454
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5116,014,420 - 116,023,649 (+)Ensembl
RefSeq Acc Id: NM_173800   ⟹   NP_776161
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385115,962,475 - 116,027,606 (+)NCBI
GRCh375115,298,151 - 115,363,303 (+)NCBI
Build 365115,326,170 - 115,391,199 (+)NCBI Archive
Celera5111,246,534 - 111,311,673 (+)RGD
HuRef5110,478,890 - 110,544,021 (+)ENTREZGENE
CHM1_15114,730,769 - 114,796,042 (+)NCBI
T2T-CHM13v2.05116,474,883 - 116,539,987 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047416913   ⟹   XP_047272869
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385115,964,680 - 116,027,606 (+)NCBI
RefSeq Acc Id: XM_047416914   ⟹   XP_047272870
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385115,965,748 - 116,027,606 (+)NCBI
RefSeq Acc Id: XM_047416915   ⟹   XP_047272871
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385115,963,380 - 116,027,606 (+)NCBI
RefSeq Acc Id: XM_047416916   ⟹   XP_047272872
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385115,992,151 - 116,027,606 (+)NCBI
RefSeq Acc Id: XM_047416917   ⟹   XP_047272873
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385115,997,541 - 116,027,606 (+)NCBI
RefSeq Acc Id: XM_047416918   ⟹   XP_047272874
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385115,994,732 - 116,027,606 (+)NCBI
RefSeq Acc Id: XM_047416919   ⟹   XP_047272875
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385115,993,770 - 116,027,606 (+)NCBI
RefSeq Acc Id: XM_054352017   ⟹   XP_054207992
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.05116,480,218 - 116,539,987 (+)NCBI
RefSeq Acc Id: XM_054352018   ⟹   XP_054207993
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.05116,475,788 - 116,539,987 (+)NCBI
RefSeq Acc Id: XM_054352019   ⟹   XP_054207994
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.05116,504,548 - 116,539,987 (+)NCBI
RefSeq Acc Id: XM_054352020   ⟹   XP_054207995
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.05116,509,916 - 116,539,987 (+)NCBI
RefSeq Acc Id: XM_054352021   ⟹   XP_054207996
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.05116,507,132 - 116,539,987 (+)NCBI
RefSeq Acc Id: XM_054352022   ⟹   XP_054207997
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.05116,506,166 - 116,539,987 (+)NCBI
Protein Sequences
Protein RefSeqs NP_776161 (Get FASTA)   NCBI Sequence Viewer  
  XP_047272869 (Get FASTA)   NCBI Sequence Viewer  
  XP_047272870 (Get FASTA)   NCBI Sequence Viewer  
  XP_047272871 (Get FASTA)   NCBI Sequence Viewer  
  XP_047272872 (Get FASTA)   NCBI Sequence Viewer  
  XP_047272873 (Get FASTA)   NCBI Sequence Viewer  
  XP_047272874 (Get FASTA)   NCBI Sequence Viewer  
  XP_047272875 (Get FASTA)   NCBI Sequence Viewer  
  XP_054207992 (Get FASTA)   NCBI Sequence Viewer  
  XP_054207993 (Get FASTA)   NCBI Sequence Viewer  
  XP_054207994 (Get FASTA)   NCBI Sequence Viewer  
  XP_054207995 (Get FASTA)   NCBI Sequence Viewer  
  XP_054207996 (Get FASTA)   NCBI Sequence Viewer  
  XP_054207997 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH60869 (Get FASTA)   NCBI Sequence Viewer  
  AAH68560 (Get FASTA)   NCBI Sequence Viewer  
  AAI09023 (Get FASTA)   NCBI Sequence Viewer  
  AAI09024 (Get FASTA)   NCBI Sequence Viewer  
  AAS66719 (Get FASTA)   NCBI Sequence Viewer  
  BAC11422 (Get FASTA)   NCBI Sequence Viewer  
  BAF84344 (Get FASTA)   NCBI Sequence Viewer  
  EAW48946 (Get FASTA)   NCBI Sequence Viewer  
  EAW48947 (Get FASTA)   NCBI Sequence Viewer  
  EAW48948 (Get FASTA)   NCBI Sequence Viewer  
  EAW48949 (Get FASTA)   NCBI Sequence Viewer  
  EAW48950 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000350541
  ENSP00000350541.4
  ENSP00000423604.1
  ENSP00000427418.1
  ENSP00000427500.1
  ENSP00000427574.1
GenBank Protein Q6Q4G3 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_776161   ⟸   NM_173800
- UniProtKB: Q86XA3 (UniProtKB/Swiss-Prot),   Q4G0V2 (UniProtKB/Swiss-Prot),   Q4G0I9 (UniProtKB/Swiss-Prot),   Q32MR1 (UniProtKB/Swiss-Prot),   C9JGD2 (UniProtKB/Swiss-Prot),   A8K6J0 (UniProtKB/Swiss-Prot),   Q8NBZ2 (UniProtKB/Swiss-Prot),   Q6Q4G3 (UniProtKB/Swiss-Prot),   Q0P5U8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000427418   ⟸   ENST00000503329
RefSeq Acc Id: ENSP00000423604   ⟸   ENST00000504467
RefSeq Acc Id: ENSP00000427500   ⟸   ENST00000512314
RefSeq Acc Id: ENSP00000378899   ⟸   ENST00000395528
RefSeq Acc Id: ENSP00000350541   ⟸   ENST00000357872
RefSeq Acc Id: ENSP00000427574   ⟸   ENST00000514509
RefSeq Acc Id: XP_047272871   ⟸   XM_047416915
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047272869   ⟸   XM_047416913
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047272870   ⟸   XM_047416914
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047272872   ⟸   XM_047416916
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047272875   ⟸   XM_047416919
- Peptide Label: isoform X5
RefSeq Acc Id: XP_047272874   ⟸   XM_047416918
- Peptide Label: isoform X5
RefSeq Acc Id: XP_047272873   ⟸   XM_047416917
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054207993   ⟸   XM_054352018
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054207992   ⟸   XM_054352017
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054207994   ⟸   XM_054352019
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054207997   ⟸   XM_054352022
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054207996   ⟸   XM_054352021
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054207995   ⟸   XM_054352020
- Peptide Label: isoform X4
Protein Domains
Aminopeptidase N-like N-terminal   ERAP1-like C-terminal   Peptidase M1 membrane alanine aminopeptidase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6Q4G3-F1-model_v2 AlphaFold Q6Q4G3 1-990 view protein structure

Promoters
RGD ID:6870328
Promoter ID:EPDNEW_H8329
Type:initiation region
Name:LVRN_1
Description:laeverin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H8330  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385115,962,475 - 115,962,535EPDNEW
RGD ID:6870330
Promoter ID:EPDNEW_H8330
Type:initiation region
Name:LVRN_2
Description:laeverin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H8329  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385115,962,591 - 115,962,651EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:26904 AgrOrtholog
COSMIC LVRN COSMIC
Ensembl Genes ENSG00000172901 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000357872 ENTREZGENE
  ENST00000357872.9 UniProtKB/Swiss-Prot
  ENST00000503329.5 UniProtKB/Swiss-Prot
  ENST00000504467.5 UniProtKB/Swiss-Prot
  ENST00000512314.5 UniProtKB/Swiss-Prot
  ENST00000514509.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.390.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.50.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1730 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.1910 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000172901 GTEx
HGNC ID HGNC:26904 ENTREZGENE
Human Proteome Map LVRN Human Proteome Map
InterPro Aminopeptidase_N-like_N UniProtKB/Swiss-Prot
  Aminopeptidase_N-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aminopeptidase_N-like_N UniProtKB/TrEMBL
  ERAP1-like_C_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  M1_APN-typ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M4/M1_CTD_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:206338 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 206338 ENTREZGENE
OMIM 610046 OMIM
PANTHER AMINOPEPTIDASE Q UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEASE M1 ZINC METALLOPROTEASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ERAP1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA166181553 PharmGKB
PRINTS ALADIPTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ZINC_PROTEASE UniProtKB/Swiss-Prot
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF63737 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8K6J0 ENTREZGENE
  AMPQ_HUMAN UniProtKB/Swiss-Prot
  C9JGD2 ENTREZGENE
  Q0P5U8 ENTREZGENE, UniProtKB/TrEMBL
  Q32MR1 ENTREZGENE
  Q4G0I9 ENTREZGENE
  Q4G0V2 ENTREZGENE
  Q6Q4G3 ENTREZGENE
  Q86XA3 ENTREZGENE
  Q8NBZ2 ENTREZGENE
UniProt Secondary A8K6J0 UniProtKB/Swiss-Prot
  C9JGD2 UniProtKB/Swiss-Prot
  Q32MR1 UniProtKB/Swiss-Prot
  Q4G0I9 UniProtKB/Swiss-Prot
  Q4G0V2 UniProtKB/Swiss-Prot
  Q86XA3 UniProtKB/Swiss-Prot
  Q8NBZ2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-02-18 LVRN  laeverin  AQPEP    Symbol and/or name change 5135510 APPROVED
2014-01-14 AQPEP  laeverin  LVRN    Symbol and/or name change 5135510 APPROVED
2014-01-07 LVRN  laeverin  AQPEP    Symbol and/or name change 5135510 APPROVED
2011-07-27 AQPEP  laeverin  LVRN  laeverin  Symbol and/or name change 5135510 APPROVED