Gene: CLCA1 (chloride channel accessory 1) Homo sapiens
Symbol: CLCA1
Name: chloride channel accessory 1
Description: This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CACC; CaCC-1; CACC1; calcium-activated chloride channel family member 1; calcium-activated chloride channel protein 1; calcium-activated chloride channel regulator 1; calcium-dependent chloride channel-1; chloride channel regulator 1; chloride channel, calcium activated, family member 1; CLCA family member 1, chloride channel regulator; CLCRG1; FLJ95147; GOB5; hCaCC-1; hCLCA1; OTTHUMP00000011907
Mus musculus (house mouse) : Clca1 (chloride channel accessory 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Clca1 (chloride channel accessory 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clca1 (chloride channel accessory 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CLCA1 (chloride channel accessory 1)
Canis lupus familiaris (dog) : CLCA1 (chloride channel accessory 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38186,468,843 - 86,500,294 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37186,934,526 - 86,965,977 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36186,707,114 - 86,738,565 (+)NCBINCBI36hg18NCBI36
Build 34186,646,071 - 86,677,963NCBI
Celera185,178,525 - 85,209,980 (+)NCBI
Cytogenetic Map1p22.3NCBI
HuRef185,045,156 - 85,076,624 (+)NCBIHuRef
CHM1_1187,049,378 - 87,080,831 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CLCA1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314775
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2018-03-13
Status: ACTIVE