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Gene: KLK7 (kallikrein related peptidase 7) Homo sapiens

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Symbol:

KLK7

Name:

kallikrein related peptidase 7

RGD ID:

1315024

HGNC Page

HGNC:6368

Description:

Enables peptidase activity. Involved in positive regulation of antibacterial peptide production. Located in epidermal lamellar body and extracellular space.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

hK7; hSCCE; kallikrein 7 (chymotryptic, stratum corneum); kallikrein-7; kallikrein-related peptidase 7; protease, serine, 6; PRSS6; SCCE; serine protease 6; signal protein; stratum corneum chymotryptic enzyme

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	50,976,468 - 50,984,064 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	50,976,468 - 50,984,099 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	51,479,724 - 51,487,320 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	56,171,541 - 56,178,962 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	48,531,233 - 48,539,211 (-)	NCBI		Celera
Cytogenetic Map	19	q13.41	NCBI
HuRef	19	47,813,130 - 47,820,053 (-)	NCBI		HuRef
CHM1_1	19	51,481,810 - 51,489,320 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	54,064,867 - 54,072,534 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
KLK7	Human	17beta-estradiol	multiple interactions	EXP		6480464	[Estradiol co-treated with TGFB1 protein] results in decreased expression of KLK7 mRNA	CTD	PMID:30165855
KLK7	Human	17beta-hydroxy-5alpha-androstan-3-one	increases expression	EXP		6480464	Dihydrotestosterone results in increased expression of KLK7 mRNA	CTD	PMID:17254854
KLK7	Human	4,4'-diaminodiphenylmethane	decreases expression	ISO	Klk7 (Mus musculus)	6480464	4 and 4'-diaminodiphenylmethane results in decreased expression of KLK7 mRNA	CTD	PMID:18648102
KLK7	Human	6-propyl-2-thiouracil	increases expression	ISO	Klk7 (Rattus norvegicus)	6480464	Propylthiouracil results in increased expression of KLK7 mRNA	CTD	PMID:24780913
KLK7	Human	acrylamide	decreases expression	ISO	Klk7 (Rattus norvegicus)	6480464	Acrylamide results in decreased expression of KLK7 mRNA	CTD	PMID:28959563
KLK7	Human	all-trans-retinoic acid	increases expression	EXP		6480464	Tretinoin results in increased expression of KLK7 mRNA	CTD	PMID:16249480
KLK7	Human	alpha-Zearalanol	multiple interactions	ISO	Klk7 (Rattus norvegicus)	6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of KLK7 mRNA	CTD	PMID:35163327
KLK7	Human	alpha-Zearalanol	decreases expression	ISO	Klk7 (Rattus norvegicus)	6480464	Zeranol results in decreased expression of KLK7 mRNA	CTD	PMID:35163327
KLK7	Human	aristolochic acid A	decreases expression	ISO	Klk7 (Rattus norvegicus)	6480464	aristolochic acid I results in decreased expression of KLK7 mRNA	CTD	PMID:17483316
KLK7	Human	arsane	multiple interactions	EXP		6480464	[sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of KLK7 mRNA	CTD	PMID:32525701
KLK7	Human	arsenic atom	multiple interactions	EXP		6480464	[sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of KLK7 mRNA	CTD	PMID:32525701
KLK7	Human	benzo[a]pyrene	multiple interactions	ISO	Klk7 (Mus musculus)	6480464	Benzo(a)pyrene promotes the reaction [AHR protein binds to KLK7 promoter]	CTD	PMID:19654925
KLK7	Human	benzo[a]pyrene	increases methylation	EXP		6480464	Benzo(a)pyrene results in increased methylation of KLK7 5' UTR and Benzo(a)pyrene results in increased methylation of KLK7 promoter	CTD	PMID:27901495
KLK7	Human	bis(2-ethylhexyl) phthalate	decreases expression	EXP		6480464	Diethylhexyl Phthalate results in decreased expression of KLK7 mRNA	CTD	PMID:31163220
KLK7	Human	bisphenol A	decreases expression	ISO	Klk7 (Rattus norvegicus)	6480464	bisphenol A results in decreased expression of KLK7 mRNA	CTD	PMID:25181051
KLK7	Human	cadmium atom	increases expression	EXP		6480464	Cadmium results in increased expression of KLK7 mRNA	CTD	PMID:21120746
KLK7	Human	calcitriol	increases expression	EXP		6480464	Calcitriol results in increased expression of KLK7 mRNA	CTD	PMID:26485663
KLK7	Human	carbamazepine	affects expression	EXP		6480464	Carbamazepine affects the expression of KLK7 mRNA	CTD	PMID:25979313
KLK7	Human	CGP 52608	multiple interactions	EXP		6480464	CGP 52608 promotes the reaction [RORA protein binds to KLK7 gene]	CTD	PMID:28238834
KLK7	Human	cisplatin	affects response to substance	EXP		6480464	KLK7 protein affects the susceptibility to Cisplatin	CTD	PMID:16217747
KLK7	Human	exemestane	increases expression	EXP		6480464	exemestane results in increased expression of KLK7 mRNA	CTD	PMID:17254854
KLK7	Human	formaldehyde	decreases expression	EXP		6480464	Formaldehyde results in decreased expression of KLK7 mRNA	CTD	PMID:27905399
KLK7	Human	furan	increases methylation	ISO	Klk7 (Rattus norvegicus)	6480464	furan results in increased methylation of KLK7 gene	CTD	PMID:22079235
KLK7	Human	indole-3-methanol	affects expression	ISO	Klk7 (Rattus norvegicus)	6480464	indole-3-carbinol affects the expression of KLK7 mRNA	CTD	PMID:21396975
KLK7	Human	pentanal	increases expression	EXP		6480464	pentanal results in increased expression of KLK7 mRNA	CTD	PMID:26079696
KLK7	Human	perfluorohexanesulfonic acid	increases expression	ISO	Klk7 (Mus musculus)	6480464	perfluorohexanesulfonic acid results in increased expression of KLK7 mRNA	CTD	PMID:37995155
KLK7	Human	perfluorooctanoic acid	multiple interactions	ISO	Klk7 (Rattus norvegicus)	6480464	[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of KLK7 mRNA	CTD	PMID:35163327
KLK7	Human	potassium dichromate	increases expression	ISO	Klk7 (Mus musculus)	6480464	Potassium Dichromate results in increased expression of KLK7 mRNA	CTD	PMID:23608068
KLK7	Human	sodium arsenate	multiple interactions	EXP		6480464	[sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of KLK7 mRNA	CTD	PMID:32525701
KLK7	Human	sodium arsenite	decreases expression	EXP		6480464	sodium arsenite results in decreased expression of KLK7 mRNA	CTD	PMID:12634122
KLK7	Human	sodium arsenite	increases expression	ISO	Klk7 (Mus musculus)	6480464	sodium arsenite results in increased expression of KLK7 mRNA	CTD	PMID:37682722
KLK7	Human	sodium fluoride	decreases expression	ISO	Klk7 (Mus musculus)	6480464	Sodium Fluoride results in decreased expression of KLK7 mRNA	CTD	PMID:27862939
KLK7	Human	Tesaglitazar	increases expression	ISO	Klk7 (Rattus norvegicus)	6480464	tesaglitazar results in increased expression of KLK7 mRNA	CTD	PMID:21515302
KLK7	Human	thioacetamide	decreases expression	ISO	Klk7 (Rattus norvegicus)	6480464	Thioacetamide results in decreased expression of KLK7 mRNA	CTD	PMID:23411599
KLK7	Human	trichloroethene	decreases expression	ISO	Klk7 (Rattus norvegicus)	6480464	Trichloroethylene results in decreased expression of KLK7 mRNA	CTD	PMID:33387578
KLK7	Human	triclosan	increases expression	EXP		6480464	Triclosan results in increased expression of KLK7 mRNA	CTD	PMID:30510588

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
KLK7	Human	epidermis development	involved_in	TAS		150520179	PMID:8034709	PINC	PMID:8034709
KLK7	Human	extracellular matrix disassembly	involved_in	TAS		150520179		Reactome	Reactome:R-HSA-1474228
KLK7	Human	positive regulation of antibacterial peptide production	involved_in	IMP		150520179	PMID:17012259	UniProt	PMID:17012259
KLK7	Human	protein maturation	involved_in	IBA	MGI:109267 more ...	150520179		GO_Central	GO_REF:0000033
KLK7	Human	proteolysis	involved_in	IEA	UniProtKB-KW:KW-0645	150520179		UniProt	GO_REF:0000043
KLK7	Human	proteolysis	involved_in	IEA	InterPro:IPR001254 and InterPro:IPR018114	150520179		InterPro	GO_REF:0000002

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
KLK7	Human	cornified envelope	is_active_in	IEA	UniProtKB:Q91VE3 and ensembl:ENSMUSP00000032955	150520179		Ensembl	GO_REF:0000107
KLK7	Human	epidermal lamellar body	located_in	IDA		150520179	PMID:15675955	UniProt	PMID:15675955
KLK7	Human	extracellular region	located_in	IEA	UniProtKB-SubCell:SL-0243	150520179		UniProt	GO_REF:0000044
KLK7	Human	extracellular region	located_in	IEA	UniProtKB-KW:KW-0964	150520179		UniProt	GO_REF:0000043
KLK7	Human	extracellular region	located_in	TAS		150520179		Reactome	Reactome:R-HSA-3827958
KLK7	Human	extracellular space	located_in	IMP		150520179	PMID:17012259	UniProt	PMID:17012259
KLK7	Human	extracellular space	is_active_in	IBA	MGI:109266 more ...	150520179		GO_Central	GO_REF:0000033
KLK7	Human	secretory granule	is_active_in	IBA	MGI:3615275 more ...	150520179		GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
KLK7	Human	hydrolase activity	enables	IEA	UniProtKB-KW:KW-0378	150520179		UniProt	GO_REF:0000043
KLK7	Human	metalloendopeptidase activity	enables	TAS		150520179		Reactome	Reactome:R-HSA-3827958
KLK7	Human	peptidase activity	enables	IMP		150520179	PMID:17012259	UniProt	PMID:17012259
KLK7	Human	peptidase activity	enables	IEA	UniProtKB-KW:KW-0645	150520179		UniProt	GO_REF:0000043
KLK7	Human	serine-type endopeptidase activity	enables	IEA	InterPro:IPR001254 and InterPro:IPR018114	150520179		InterPro	GO_REF:0000002
KLK7	Human	serine-type endopeptidase activity	enables	IBA	MGI:109267 more ...	150520179		GO_Central	GO_REF:0000033
KLK7	Human	serine-type peptidase activity	enables	TAS		150520179	PMID:8034709	PINC	PMID:8034709
KLK7	Human	serine-type peptidase activity	enables	IEA	UniProtKB-KW:KW-0720	150520179		UniProt	GO_REF:0000043

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:7794273	PMID:8034709	PMID:8393902	PMID:8889549	PMID:10974542	PMID:11054574	PMID:12477932	PMID:12738725	PMID:14691584	PMID:14972646	PMID:15140227	PMID:15191543
PMID:15297163	PMID:15489334	PMID:15675955	PMID:15766562	PMID:16344560	PMID:16628198	PMID:16800723	PMID:16800724	PMID:17012259	PMID:17275179	PMID:17909180	PMID:17989887
PMID:18163887	PMID:18325919	PMID:18329042	PMID:18343220	PMID:18774391	PMID:18953252	PMID:18976018	PMID:19085836	PMID:19091121	PMID:19118981	PMID:19350120	PMID:19423540
PMID:19453546	PMID:19558318	PMID:19921697	PMID:20090765	PMID:20332224	PMID:20406964	PMID:20424135	PMID:20438785	PMID:20544292	PMID:20665732	PMID:20944116	PMID:21168996
PMID:21520985	PMID:21548205	PMID:21616098	PMID:21832049	PMID:21868565	PMID:21873635	PMID:22521249	PMID:22573795	PMID:22825846	PMID:23224034	PMID:23413953	PMID:23495698
PMID:25153388	PMID:25182706	PMID:25448018	PMID:25477184	PMID:25640309	PMID:26022646	PMID:26032414	PMID:26186194	PMID:26231762	PMID:27279059	PMID:27478344	PMID:27769847
PMID:28479159	PMID:28514442	PMID:28636767	PMID:29229980	PMID:29319165	PMID:29498930	PMID:29779317	PMID:30644845	PMID:30705123	PMID:31180492	PMID:31883963	PMID:32323843
PMID:33276948	PMID:33588911	PMID:33961781	PMID:34525904	PMID:36543142	PMID:38189409

KLK7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	50,976,468 - 50,984,064 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	50,976,468 - 50,984,099 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	51,479,724 - 51,487,320 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	56,171,541 - 56,178,962 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	48,531,233 - 48,539,211 (-)	NCBI		Celera
Cytogenetic Map	19	q13.41	NCBI
HuRef	19	47,813,130 - 47,820,053 (-)	NCBI		HuRef
CHM1_1	19	51,481,810 - 51,489,320 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	54,064,867 - 54,072,534 (-)	NCBI		T2T-CHM13v2.0

Klk7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	43,460,718 - 43,465,811 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	43,460,718 - 43,465,783 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	43,811,294 - 43,816,387 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	43,811,294 - 43,816,359 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	51,066,814 - 51,071,729 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	43,679,486 - 43,684,401 (+)	NCBI		MGSCv36	mm8
Celera	7	39,278,059 - 39,282,925 (+)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	28.27	NCBI

Klk7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	103,403,206 - 103,407,907 (+)	NCBI		GRCr8
mRatBN7.2	1	94,267,170 - 94,271,361 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	94,266,605 - 94,271,332 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	99,652,577 - 99,656,768 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	108,125,248 - 108,129,439 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	101,414,839 - 101,419,040 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	99,749,991 - 99,754,723 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	99,749,936 - 99,754,435 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	100,818,808 - 100,823,452 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	94,243,421 - 94,246,711 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	94,320,659 - 94,323,995 (+)	NCBI
Celera	1	88,535,508 - 88,538,798 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

Klk7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955558	1,490,120 - 1,494,993 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955558	1,490,884 - 1,494,843 (+)	NCBI	ChiLan1.0	ChiLan1.0

KLK7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	57,046,646 - 57,053,670 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	58,967,738 - 58,974,995 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	47,944,072 - 47,951,506 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

KLK7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	105,891,206 - 105,895,441 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	105,464,096 - 105,467,219 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	106,399,900 - 106,404,253 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	106,400,435 - 106,403,750 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	106,071,917 - 106,075,040 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	105,713,325 - 105,716,448 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	106,508,823 - 106,511,946 (+)	NCBI		UU_Cfam_GSD_1.0

Klk7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	22,761,330 - 22,766,037 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936889	637,996 - 641,126 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936889	637,526 - 641,126 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KLK7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	55,644,628 - 55,648,961 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	55,644,627 - 55,649,000 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

KLK7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	43,998,661 - 44,021,478 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666073	24,022,871 - 24,029,762 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Klk7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	3,775,252 - 3,778,432 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	3,774,837 - 3,778,646 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in KLK7
40 total Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3	copy number gain	See cases [RCV000050883]	Chr19:50191219..58535818 [GRCh38] Chr19:50694476..59047185 [GRCh37] Chr19:55386288..63738997 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3	copy number gain	See cases [RCV000052925]	Chr19:49907832..58557889 [GRCh38] Chr19:50411089..59069256 [GRCh37] Chr19:55102901..63761068 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3	copy number gain	See cases [RCV000052914]	Chr19:47908540..58539965 [GRCh38] Chr19:48411797..59051332 [GRCh37] Chr19:53103609..63743144 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3	copy number gain	See cases [RCV000052915]	Chr19:47929575..58572206 [GRCh38] Chr19:48432832..59083573 [GRCh37] Chr19:53124644..63775385 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3	copy number gain	See cases [RCV000135843]	Chr19:50152520..58581203 [GRCh38] Chr19:50655777..59092570 [GRCh37] Chr19:55347589..63784382 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50489390-59095359)x3	copy number gain	See cases [RCV000445925]	Chr19:50489390..59095359 [GRCh37] Chr19:19q13.33-13.43	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3	copy number gain	See cases [RCV000511289]	Chr19:260912..58956888 [GRCh37] Chr19:19p13.3-q13.43	pathogenic\|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)	copy number gain	See cases [RCV000512296]	Chr19:260912..58956888 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3	copy number gain	not provided [RCV000752444]	Chr19:260912..59097160 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3	copy number gain	not provided [RCV000752439]	Chr19:68029..59110290 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50740074-59097160)x3	copy number gain	not provided [RCV000740208]	Chr19:50740074..59097160 [GRCh37] Chr19:19q13.33-13.43	pathogenic
NM_005046.4(KLK7):c.624G>T (p.Pro208=)	single nucleotide variant	not provided [RCV000962711]	Chr19:50977674 [GRCh38] Chr19:51480930 [GRCh37] Chr19:19q13.41	benign
NM_005046.4(KLK7):c.678C>T (p.Cys226=)	single nucleotide variant	not provided [RCV000966620]	Chr19:50977620 [GRCh38] Chr19:51480876 [GRCh37] Chr19:19q13.41	benign
NM_005046.4(KLK7):c.441C>T (p.Ser147=)	single nucleotide variant	not provided [RCV000951348]	Chr19:50980268 [GRCh38] Chr19:51483524 [GRCh37] Chr19:19q13.41	benign
NM_005046.4(KLK7):c.725C>T (p.Thr242Ile)	single nucleotide variant	not provided [RCV000955570]	Chr19:50977573 [GRCh38] Chr19:51480829 [GRCh37] Chr19:19q13.41	benign
GRCh37/hg19 19q13.31-13.42(chr19:44738088-53621561)x3	copy number gain	not provided [RCV001007050]	Chr19:44738088..53621561 [GRCh37] Chr19:19q13.31-13.42	pathogenic
GRCh37/hg19 19q13.32-13.42(chr19:47939842-54626871)	copy number gain	not provided [RCV001249294]	Chr19:47939842..54626871 [GRCh37] Chr19:19q13.32-13.42	not provided
GRCh37/hg19 19q13.33-13.41(chr19:50469730-51916485)x3	copy number gain	not provided [RCV001007055]	Chr19:50469730..51916485 [GRCh37] Chr19:19q13.33-13.41	uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3	copy number gain	not provided [RCV001259944]	Chr19:48463931..57095254 [GRCh37] Chr19:19q13.33-13.43	pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:49911081-53127438)	copy number gain	not specified [RCV002052689]	Chr19:49911081..53127438 [GRCh37] Chr19:19q13.33-13.41	likely pathogenic
NM_005046.4(KLK7):c.341T>C (p.Met114Thr)	single nucleotide variant	not specified [RCV004314024]	Chr19:50980368 [GRCh38] Chr19:51483624 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.261C>G (p.Asp87Glu)	single nucleotide variant	not specified [RCV004076674]	Chr19:50980448 [GRCh38] Chr19:51483704 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.127T>C (p.Trp43Arg)	single nucleotide variant	not specified [RCV004237449]	Chr19:50981861 [GRCh38] Chr19:51485117 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.493T>A (p.Cys165Ser)	single nucleotide variant	not specified [RCV004114726]	Chr19:50979901 [GRCh38] Chr19:51483157 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.515C>G (p.Ser172Cys)	single nucleotide variant	not specified [RCV004141780]	Chr19:50979879 [GRCh38] Chr19:51483135 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.232G>A (p.Val78Met)	single nucleotide variant	not specified [RCV004225772]	Chr19:50980477 [GRCh38] Chr19:51483733 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.595A>C (p.Asn199His)	single nucleotide variant	not specified [RCV004239576]	Chr19:50979799 [GRCh38] Chr19:51483055 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.26T>A (p.Leu9Gln)	single nucleotide variant	not specified [RCV004154001]	Chr19:50982374 [GRCh38] Chr19:51485630 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.458C>T (p.Thr153Met)	single nucleotide variant	not provided [RCV004695701]\|not specified [RCV004210474]	Chr19:50980251 [GRCh38] Chr19:51483507 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.533A>G (p.Lys178Arg)	single nucleotide variant	not specified [RCV004239683]	Chr19:50979861 [GRCh38] Chr19:51483117 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.415C>T (p.Pro139Ser)	single nucleotide variant	not specified [RCV004078898]	Chr19:50980294 [GRCh38] Chr19:51483550 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.151A>C (p.Asn51His)	single nucleotide variant	not specified [RCV004276410]	Chr19:50981837 [GRCh38] Chr19:51485093 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.275G>C (p.Arg92Thr)	single nucleotide variant	not specified [RCV004262199]	Chr19:50980434 [GRCh38] Chr19:51483690 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.328G>A (p.Val110Ile)	single nucleotide variant	not specified [RCV004285189]	Chr19:50980381 [GRCh38] Chr19:51483637 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.720G>C (p.Lys240Asn)	single nucleotide variant	not specified [RCV004265868]	Chr19:50977578 [GRCh38] Chr19:51480834 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.468T>A (p.Asp156Glu)	single nucleotide variant	not specified [RCV004345332]	Chr19:50980241 [GRCh38] Chr19:51483497 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.430T>G (p.Cys144Gly)	single nucleotide variant	not specified [RCV004631595]	Chr19:50980279 [GRCh38] Chr19:51483535 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.527G>C (p.Cys176Ser)	single nucleotide variant	not specified [RCV004644218]	Chr19:50979867 [GRCh38] Chr19:51483123 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.753G>C (p.Lys251Asn)	single nucleotide variant	not specified [RCV004935730]	Chr19:50977545 [GRCh38] Chr19:51480801 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.307G>A (p.Gly103Ser)	single nucleotide variant	not specified [RCV004308038]	Chr19:50980402 [GRCh38] Chr19:51483658 [GRCh37] Chr19:19q13.41	uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3	copy number gain	not provided [RCV003485200]	Chr19:49625130..57647352 [GRCh37] Chr19:19q13.33-13.43	likely pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:48905537-51614930)x3	copy number gain	not specified [RCV003986127]	Chr19:48905537..51614930 [GRCh37] Chr19:19q13.33-13.41	likely pathogenic
NM_005046.4(KLK7):c.158T>C (p.Leu53Pro)	single nucleotide variant	not specified [RCV004409668]	Chr19:50981830 [GRCh38] Chr19:51485086 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.182A>G (p.Asn61Ser)	single nucleotide variant	not specified [RCV004409669]	Chr19:50981806 [GRCh38] Chr19:51485062 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.187C>T (p.Arg63Cys)	single nucleotide variant	not specified [RCV004409670]	Chr19:50981801 [GRCh38] Chr19:51485057 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.376T>C (p.Ser126Pro)	single nucleotide variant	not specified [RCV004409671]	Chr19:50980333 [GRCh38] Chr19:51483589 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.496G>A (p.Val166Met)	single nucleotide variant	not specified [RCV004409672]	Chr19:50979898 [GRCh38] Chr19:51483154 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.623C>T (p.Pro208Leu)	single nucleotide variant	not specified [RCV004409673]	Chr19:50977675 [GRCh38] Chr19:51480931 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.188G>C (p.Arg63Pro)	single nucleotide variant	not specified [RCV004644217]	Chr19:50981800 [GRCh38] Chr19:51485056 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.134T>C (p.Val45Ala)	single nucleotide variant	not specified [RCV004935727]	Chr19:50981854 [GRCh38] Chr19:51485110 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.202G>A (p.Ala68Thr)	single nucleotide variant	not specified [RCV004935728]	Chr19:50981786 [GRCh38] Chr19:51485042 [GRCh37] Chr19:19q13.41	uncertain significance
NM_005046.4(KLK7):c.734T>C (p.Ile245Thr)	single nucleotide variant	not specified [RCV004935729]	Chr19:50977564 [GRCh38] Chr19:51480820 [GRCh37] Chr19:19q13.41	uncertain significance

Predicted Target Of

	Summary Value
Count of predictions:	1915
Count of miRNA genes:	787
Interacting mature miRNAs:	864
Transcripts:	ENST00000304045, ENST00000336317, ENST00000391807, ENST00000593904, ENST00000595638, ENST00000595820, ENST00000597707
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
597178072	GWAS1274146_H	kallikrein-7 measurement QTL GWAS1274146 (human)		5e-154	kallikrein-7 measurement		19	50982366	50982367	Human
597178074	GWAS1274148_H	kallikrein-7 measurement QTL GWAS1274148 (human)		2e-12	kallikrein-7 measurement		19	50981325	50981326	Human
597178075	GWAS1274149_H	kallikrein-7 measurement QTL GWAS1274149 (human)		6e-30	kallikrein-7 measurement		19	50979695	50979696	Human
597440895	GWAS1536969_H	kallikrein-7 measurement QTL GWAS1536969 (human)		1e-45	kallikrein-7 measurement		19	50983811	50983812	Human
597300691	GWAS1396765_H	kallikrein-7 measurement QTL GWAS1396765 (human)		1e-66	kallikrein-7 measurement		19	50981306	50981307	Human
597309047	GWAS1405121_H	vaginal microbiome measurement QTL GWAS1405121 (human)		0.000001	vaginal microbiome measurement		19	50978977	50978978	Human
597122746	GWAS1218820_H	blood protein measurement QTL GWAS1218820 (human)		7e-33	blood protein amount (VT:0005416)	blood protein measurement (CMO:0000028)	19	50983919	50983920	Human
597178071	GWAS1274145_H	kallikrein-7 measurement QTL GWAS1274145 (human)		5e-34	kallikrein-7 measurement		19	50976847	50976848	Human
597051033	GWAS1147107_H	protein measurement QTL GWAS1147107 (human)		6e-08	protein measurement		19	50981938	50981939	Human
1559110	SCL22_H	Serum cholesterol level QTL 22 (human)	3.59	0.000241	Lipid level	LDL cholesterol	19	31907594	57907594	Human
597140230	GWAS1236304_H	level of kallikrein-10 in blood serum QTL GWAS1236304 (human)		1e-20	level of kallikrein-10 in blood serum		19	50977726	50977727	Human
597291947	GWAS1388021_H	kallikrein-7 measurement QTL GWAS1388021 (human)		1e-15	kallikrein-7 measurement		19	50982366	50982367	Human
597477416	GWAS1573490_H	blood protein measurement QTL GWAS1573490 (human)		2e-44	blood protein amount (VT:0005416)	blood protein measurement (CMO:0000028)	19	50983811	50983812	Human
597077295	GWAS1173369_H	blood protein measurement QTL GWAS1173369 (human)		4e-24	blood protein amount (VT:0005416)	blood protein measurement (CMO:0000028)	19	50979506	50979507	Human
597266851	GWAS1362925_H	kallikrein-7 measurement QTL GWAS1362925 (human)		3e-71	kallikrein-7 measurement		19	50977573	50977574	Human
597310784	GWAS1406858_H	vaginal microbiome measurement QTL GWAS1406858 (human)		0.000006	vaginal microbiome measurement		19	50978977	50978978	Human
597272963	GWAS1369037_H	kallikrein-7 measurement QTL GWAS1369037 (human)		2e-29	kallikrein-7 measurement		19	50979695	50979696	Human
597272962	GWAS1369036_H	kallikrein-7 measurement QTL GWAS1369036 (human)		5e-53	kallikrein-7 measurement		19	50982366	50982367	Human
1331657	COPD9_H	Chronic obstructive pulmonary disease QTL 9 (human)	1.94		Chronic airflow obstruction	post-bronchodilator FEV1	19	31021760	57021760	Human

D19S1082

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	19	51,480,648 - 51,480,751	UniSTS	GRCh37
Build 36	19	56,172,460 - 56,172,563	RGD	NCBI36
Celera	19	48,532,152 - 48,532,251	RGD
Cytogenetic Map	19	q13.41	UniSTS
HuRef	19	47,814,043 - 47,814,142	UniSTS

KLK7_7860

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	19	51,480,402 - 51,480,865	UniSTS	GRCh37
Build 36	19	56,172,214 - 56,172,677	RGD	NCBI36
Celera	19	48,531,906 - 48,532,365	RGD
HuRef	19	47,813,797 - 47,814,256	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system	visual system
1112	2237	2609	1965	4779	1377	1931	5	365	1142	206	2124	5552	5221	33	3641	1	676	1656	1471	174	1


RefSeq Transcripts	NM_001207053	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001243126	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_005046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_139277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	A42048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AA101043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC011483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF166330	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF243527	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF332583	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF411214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF411215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AI049783	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK289660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK295313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY601109	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY646152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC032005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471135	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CQ785390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA243628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA307925	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ018784	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KF963189	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KF963190	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KF963191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KF963192	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KF963193	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX519464	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KX519465	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L33404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	MN510775	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	MN510776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000304045 ⟹ ENSP00000304791

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	50,976,482 - 50,984,099 (-)	Ensembl

Ensembl Acc Id:

ENST00000391807 ⟹ ENSP00000375683

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	50,976,488 - 50,983,815 (-)	Ensembl

Ensembl Acc Id:

ENST00000593904 ⟹ ENSP00000470084

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	50,980,286 - 50,983,914 (-)	Ensembl

Ensembl Acc Id:

ENST00000595638

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	50,982,095 - 50,984,064 (-)	Ensembl

Ensembl Acc Id:

ENST00000595820 ⟹ ENSP00000470538

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	50,976,468 - 50,983,917 (-)	Ensembl

Ensembl Acc Id:

ENST00000597707 ⟹ ENSP00000469950

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	50,977,359 - 50,984,038 (-)	Ensembl

RefSeq Acc Id:

NM_001207053 ⟹ NP_001193982

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	50,976,468 - 50,983,917 (-)	NCBI
GRCh37	19	51,479,735 - 51,487,320 (-)	ENTREZGENE
HuRef	19	47,813,130 - 47,820,053 (-)	ENTREZGENE
CHM1_1	19	51,481,810 - 51,489,320 (-)	NCBI
T2T-CHM13v2.0	19	54,064,867 - 54,072,387 (-)	NCBI

Sequence:

show sequence

GAAGATTTTGGAGCCCAGCTGTGTGCCAGCCCAAGTCGGAACTTGGATCACATCAGATCCTCTCGAGCCCAGGGTGACAAGATTATTGATGGCGCCCCATGTGCAAGAGGCTCCCACCCATGGCAGGT
GGCCCTGCTCAGTGGCAATCAGCTCCACTGCGGAGGCGTCCTGGTCAATGAGCGCTGGGTGCTCACTGCCGCCCACTGCAAGATGAATGAGTACACCGTGCACCTGGGCAGTGATACGCTGGGCGACA
GGAGAGCTCAGAGGATCAAGGCCTCGAAGTCATTCCGCCACCCCGGCTACTCCACACAGACCCATGTTAATGACCTCATGCTCGTGAAGCTCAATAGCCAGGCCAGGCTGTCATCCATGGTGAAGAAA
GTCAGGCTGCCCTCCCGCTGCGAACCCCCTGGAACCACCTGTACTGTCTCCGGCTGGGGCACTACCACGAGCCCAGATGTGACCTTTCCCTCTGACCTCATGTGCGTGGATGTCAAGCTCATCTCCCC
CCAGGACTGCACGAAGGTTTACAAGGACTTACTGGAAAATTCCATGCTGTGCGCTGGCATCCCCGACTCCAAGAAAAACGCCTGCAATGGTGACTCAGGGGGACCGTTGGTGTGCAGAGGTACCCTGC
AAGGTCTGGTGTCCTGGGGAACTTTCCCTTGCGGCCAACCCAATGACCCAGGAGTCTACACTCAAGTGTGCAAGTTCACCAAGTGGATAAATGACACCATGAAAAAGCATCGCTAACGCCACACTGAG
TTAATTAACTGTGTGCTTCCAACAGAAAATGCACAGGAGTGAGGACGCCGATGACCTATGAAGTCAAATTTGACTTTACCTTTCCTCAAAGATATATTTAAACCAACCTCATGCCCTGTTGATAAACC
AATCAAATTGGTAAAGACCTAAAACCAAAACAAATAAAGAAACACAAAACCCTCAGTGCTGGAGAAGAGTCAGTGAGACCAGCACTCTCAAACACTGGAACTGGACGTTCGTACAGTCTTTACGGAAG
ACACTTGGTCAACGTACACCGAGACCCTTATTCACCACCTTTGACCCAGTAACTCTAATCTTAGGAAGAACCTACTGAAACAAAAAAAATCCAAAATGTAGAACAAGACTTGAATTTACCATGATATT
ATTTATCACAGAAATGAAGTGAAACCATCAAACATGTTCCAAAAGTACCAGATGGCTTAAATAATAGTCTGGCTTGGCACAACGATGTTTTTTTTCTTTGAGACAGAGTCTCTGTTGCTTGGGCTGCA
ATGCAGTGATGCAATCTTGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCGTGCTTCAGCCTCCCAAGTACCTGGGACTACAGGTGTGCACCACCACACCAGGCTAATTTTTTGTGTAT
TTTTACTAGAGACAGGGTTTCACCATGTTGGCCAGCATGGTCTTGAACGCCTGACCTCAGATGATCCACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGGCCAGCCCACA
ATGATATTACAAACCTATTAAAAATGATACTTAGACAGAATTGTCAGTATTATTCAAGAACATTTAGGCTATAGGATGTTAAATGACAAAAGGAAGGACAAAAATATATATGTATGTGACCCTACCCA
TAAAAAATGAAATATTCACAGAATCAGATCTGAAAACACATGTCCCAGACTGCATACTGGGGTCGTCATGAGGTGTCTCCTTCCTTCTGTGTACTTTTCCTTGAATGTGCACTTTTATAACATGAAAA
ATAAAGGTGGGGAAAAAAGTCTGAAGATCTAA

hide sequence

RefSeq Acc Id:

NM_001243126 ⟹ NP_001230055

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	50,976,479 - 50,984,064 (-)	NCBI
GRCh37	19	51,479,735 - 51,487,320 (-)	NCBI
HuRef	19	47,813,130 - 47,820,053 (-)	NCBI
CHM1_1	19	51,481,810 - 51,489,320 (-)	NCBI
T2T-CHM13v2.0	19	54,064,878 - 54,072,534 (-)	NCBI

Sequence:

show sequence

AATTGCTCTCGCTGCGTCAGGGTTCCAGATAACCAGAACCGCAAATGCAGGCGGGGGTGTCCCA
GAGTCGGCTCCGCCTGCACCCCAGGGCGCTGGGGCCGGGCATGGGGCGGGGGGTGATATAAGAGGACGGCCCAGCAGAGGGATGAAGATTTTGGAGCCCAGCTGTGTGCCAGCCCAAGTCGGAACTTG
GATCACATCAGATCCTCTCGAGCTCCAGCAGGAGAGGCCCTTCCTCGCCTGGCAGCCCCTGAGCGGCTCAGCAGGGCACCATGGCAAGATCCCTTCTCCTGCCCCTGCAGATCTTACTGCTATCCTTA
GCCTTGGAAACTGCAGGAGAAGAAGTGAGTACACCGTGCACCTGGGCAGTGATACGCTGGGCGACAGGAGAGCTCAGAGGATCAAGGCCTCGAAGTCATTCCGCCACCCCGGCTACTCCACACAGACC
CATGTTAATGACCTCATGCTCGTGAAGCTCAATAGCCAGGCCAGGCTGTCATCCATGGTGAAGAAAGTCAGGCTGCCCTCCCGCTGCGAACCCCCTGGAACCACCTGTACTGTCTCCGGCTGGGGCAC
TACCACGAGCCCAGATGTGACCTTTCCCTCTGACCTCATGTGCGTGGATGTCAAGCTCATCTCCCCCCAGGACTGCACGAAGGTTTACAAGGACTTACTGGAAAATTCCATGCTGTGCGCTGGCATCC
CCGACTCCAAGAAAAACGCCTGCAATGGTGACTCAGGGGGACCGTTGGTGTGCAGAGGTACCCTGCAAGGTCTGGTGTCCTGGGGAACTTTCCCTTGCGGCCAACCCAATGACCCAGGAGTCTACACT
CAAGTGTGCAAGTTCACCAAGTGGATAAATGACACCATGAAAAAGCATCGCTAACGCCACACTGAGTTAATTAACTGTGTGCTTCCAACAGAAAATGCACAGGAGTGAGGACGCCGATGACCTATGAA
GTCAAATTTGACTTTACCTTTCCTCAAAGATATATTTAAACCAACCTCATGCCCTGTTGATAAACCAATCAAATTGGTAAAGACCTAAAACCAAAACAAATAAAGAAACACAAAACCCTCAGTGCTGG
AGAAGAGTCAGTGAGACCAGCACTCTCAAACACTGGAACTGGACGTTCGTACAGTCTTTACGGAAGACACTTGGTCAACGTACACCGAGACCCTTATTCACCACCTTTGACCCAGTAACTCTAATCTT
AGGAAGAACCTACTGAAACAAAAAAAATCCAAAATGTAGAACAAGACTTGAATTTACCATGATATTATTTATCACAGAAATGAAGTGAAACCATCAAACATGTTCCAAAAGTACCAGATGGCTTAAAT
AATAGTCTGGCTTGGCACAACGATGTTTTTTTTCTTTGAGACAGAGTCTCTGTTGCTTGGGCTGCAATGCAGTGATGCAATCTTGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCGTG
CTTCAGCCTCCCAAGTACCTGGGACTACAGGTGTGCACCACCACACCAGGCTAATTTTTTGTGTATTTTTACTAGAGACAGGGTTTCACCATGTTGGCCAGCATGGTCTTGAACGCCTGACCTCAGAT
GATCCACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGGCCAGCCCACAATGATATTACAAACCTATTAAAAATGATACTTAGACAGAATTGTCAGTATTATTCAAGAACA
TTTAGGCTATAGGATGTTAAATGACAAAAGGAAGGACAAAAATATATATGTATGTGACCCTACCCATAAAAAATGAAATATTCACAGAATCAGATCTGAAAACACATGTCCCAGACTGCATACTGGGG
TCGTCATGAGGTGTCTCCTTCCTTCTGTGTACTTTTCCTTGAATGTGCACTTTTATAACATGAAAAATAAAGGTGGGGAAAAAAGTCAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_005046 ⟹ NP_005037

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	50,976,468 - 50,983,917 (-)	NCBI
GRCh37	19	51,479,735 - 51,487,320 (-)	ENTREZGENE
Build 36	19	56,171,541 - 56,178,962 (-)	NCBI Archive
HuRef	19	47,813,130 - 47,820,053 (-)	ENTREZGENE
CHM1_1	19	51,481,810 - 51,489,320 (-)	NCBI
T2T-CHM13v2.0	19	54,064,867 - 54,072,387 (-)	NCBI

Sequence:

show sequence

GAAGATTTTGGAGCCCAGCTGTGTGCCAGCCCAAGTCGGAACTTGGATCACATCAGATCCTCTCGAGCTCCAGCAGGAGAGGCCCTTCCTCGCCTGGCAGCCCCTGAGCGGCTCAGCAGGGCACCATG
GCAAGATCCCTTCTCCTGCCCCTGCAGATCTTACTGCTATCCTTAGCCTTGGAAACTGCAGGAGAAGAAGCCCAGGGTGACAAGATTATTGATGGCGCCCCATGTGCAAGAGGCTCCCACCCATGGCA
GGTGGCCCTGCTCAGTGGCAATCAGCTCCACTGCGGAGGCGTCCTGGTCAATGAGCGCTGGGTGCTCACTGCCGCCCACTGCAAGATGAATGAGTACACCGTGCACCTGGGCAGTGATACGCTGGGCG
ACAGGAGAGCTCAGAGGATCAAGGCCTCGAAGTCATTCCGCCACCCCGGCTACTCCACACAGACCCATGTTAATGACCTCATGCTCGTGAAGCTCAATAGCCAGGCCAGGCTGTCATCCATGGTGAAG
AAAGTCAGGCTGCCCTCCCGCTGCGAACCCCCTGGAACCACCTGTACTGTCTCCGGCTGGGGCACTACCACGAGCCCAGATGTGACCTTTCCCTCTGACCTCATGTGCGTGGATGTCAAGCTCATCTC
CCCCCAGGACTGCACGAAGGTTTACAAGGACTTACTGGAAAATTCCATGCTGTGCGCTGGCATCCCCGACTCCAAGAAAAACGCCTGCAATGGTGACTCAGGGGGACCGTTGGTGTGCAGAGGTACCC
TGCAAGGTCTGGTGTCCTGGGGAACTTTCCCTTGCGGCCAACCCAATGACCCAGGAGTCTACACTCAAGTGTGCAAGTTCACCAAGTGGATAAATGACACCATGAAAAAGCATCGCTAACGCCACACT
GAGTTAATTAACTGTGTGCTTCCAACAGAAAATGCACAGGAGTGAGGACGCCGATGACCTATGAAGTCAAATTTGACTTTACCTTTCCTCAAAGATATATTTAAACCAACCTCATGCCCTGTTGATAA
ACCAATCAAATTGGTAAAGACCTAAAACCAAAACAAATAAAGAAACACAAAACCCTCAGTGCTGGAGAAGAGTCAGTGAGACCAGCACTCTCAAACACTGGAACTGGACGTTCGTACAGTCTTTACGG
AAGACACTTGGTCAACGTACACCGAGACCCTTATTCACCACCTTTGACCCAGTAACTCTAATCTTAGGAAGAACCTACTGAAACAAAAAAAATCCAAAATGTAGAACAAGACTTGAATTTACCATGAT
ATTATTTATCACAGAAATGAAGTGAAACCATCAAACATGTTCCAAAAGTACCAGATGGCTTAAATAATAGTCTGGCTTGGCACAACGATGTTTTTTTTCTTTGAGACAGAGTCTCTGTTGCTTGGGCT
GCAATGCAGTGATGCAATCTTGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCGTGCTTCAGCCTCCCAAGTACCTGGGACTACAGGTGTGCACCACCACACCAGGCTAATTTTTTGTG
TATTTTTACTAGAGACAGGGTTTCACCATGTTGGCCAGCATGGTCTTGAACGCCTGACCTCAGATGATCCACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGGCCAGCCC
ACAATGATATTACAAACCTATTAAAAATGATACTTAGACAGAATTGTCAGTATTATTCAAGAACATTTAGGCTATAGGATGTTAAATGACAAAAGGAAGGACAAAAATATATATGTATGTGACCCTAC
CCATAAAAAATGAAATATTCACAGAATCAGATCTGAAAACACATGTCCCAGACTGCATACTGGGGTCGTCATGAGGTGTCTCCTTCCTTCTGTGTACTTTTCCTTGAATGTGCACTTTTATAACATGA
AAAATAAAGGTGGGGAAAAAAGTCTGAAGATCTAA

hide sequence

RefSeq Acc Id:

NM_139277 ⟹ NP_644806

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	50,976,479 - 50,983,815 (-)	NCBI
GRCh37	19	51,479,735 - 51,487,320 (-)	ENTREZGENE
Build 36	19	56,171,541 - 56,178,883 (-)	NCBI Archive
HuRef	19	47,813,130 - 47,820,053 (-)	ENTREZGENE
CHM1_1	19	51,481,810 - 51,489,071 (-)	NCBI
T2T-CHM13v2.0	19	54,064,878 - 54,072,285 (-)	NCBI

Sequence:

show sequence

GGAGAGGGTGATGCTGGCTCCAAGCCTGACTCTGCTCTCGAGAGCTCCAGCAGGAGAGGCCCTT
CCTCGCCTGGCAGCCCCTGAGCGGCTCAGCAGGGCACCATGGCAAGATCCCTTCTCCTGCCCCTGCAGATCTTACTGCTATCCTTAGCCTTGGAAACTGCAGGAGAAGAAGCCCAGGGTGACAAGATT
ATTGATGGCGCCCCATGTGCAAGAGGCTCCCACCCATGGCAGGTGGCCCTGCTCAGTGGCAATCAGCTCCACTGCGGAGGCGTCCTGGTCAATGAGCGCTGGGTGCTCACTGCCGCCCACTGCAAGAT
GAATGAGTACACCGTGCACCTGGGCAGTGATACGCTGGGCGACAGGAGAGCTCAGAGGATCAAGGCCTCGAAGTCATTCCGCCACCCCGGCTACTCCACACAGACCCATGTTAATGACCTCATGCTCG
TGAAGCTCAATAGCCAGGCCAGGCTGTCATCCATGGTGAAGAAAGTCAGGCTGCCCTCCCGCTGCGAACCCCCTGGAACCACCTGTACTGTCTCCGGCTGGGGCACTACCACGAGCCCAGATGTGACC
TTTCCCTCTGACCTCATGTGCGTGGATGTCAAGCTCATCTCCCCCCAGGACTGCACGAAGGTTTACAAGGACTTACTGGAAAATTCCATGCTGTGCGCTGGCATCCCCGACTCCAAGAAAAACGCCTG
CAATGGTGACTCAGGGGGACCGTTGGTGTGCAGAGGTACCCTGCAAGGTCTGGTGTCCTGGGGAACTTTCCCTTGCGGCCAACCCAATGACCCAGGAGTCTACACTCAAGTGTGCAAGTTCACCAAGT
GGATAAATGACACCATGAAAAAGCATCGCTAACGCCACACTGAGTTAATTAACTGTGTGCTTCCAACAGAAAATGCACAGGAGTGAGGACGCCGATGACCTATGAAGTCAAATTTGACTTTACCTTTC
CTCAAAGATATATTTAAACCAACCTCATGCCCTGTTGATAAACCAATCAAATTGGTAAAGACCTAAAACCAAAACAAATAAAGAAACACAAAACCCTCAGTGCTGGAGAAGAGTCAGTGAGACCAGCA
CTCTCAAACACTGGAACTGGACGTTCGTACAGTCTTTACGGAAGACACTTGGTCAACGTACACCGAGACCCTTATTCACCACCTTTGACCCAGTAACTCTAATCTTAGGAAGAACCTACTGAAACAAA
AAAAATCCAAAATGTAGAACAAGACTTGAATTTACCATGATATTATTTATCACAGAAATGAAGTGAAACCATCAAACATGTTCCAAAAGTACCAGATGGCTTAAATAATAGTCTGGCTTGGCACAACG
ATGTTTTTTTTCTTTGAGACAGAGTCTCTGTTGCTTGGGCTGCAATGCAGTGATGCAATCTTGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCGTGCTTCAGCCTCCCAAGTACCTGG
GACTACAGGTGTGCACCACCACACCAGGCTAATTTTTTGTGTATTTTTACTAGAGACAGGGTTTCACCATGTTGGCCAGCATGGTCTTGAACGCCTGACCTCAGATGATCCACCCACCTTGGCCTCCC
AAAGTGCTGGGATTACAGGCATGAGCCACCACGGCCAGCCCACAATGATATTACAAACCTATTAAAAATGATACTTAGACAGAATTGTCAGTATTATTCAAGAACATTTAGGCTATAGGATGTTAAAT
GACAAAAGGAAGGACAAAAATATATATGTATGTGACCCTACCCATAAAAAATGAAATATTCACAGAATCAGATCTGAAAACACATGTCCCAGACTGCATACTGGGGTCGTCATGAGGTGTCTCCTTCC
TTCTGTGTACTTTTCCTTGAATGTGCACTTTTATAACATGAAAAATAAAGGTGGGGAAAAAAGTCAAAAAAAAAAAAA

hide sequence


Protein RefSeqs	NP_001193982	(Get FASTA)	NCBI Sequence Viewer
	NP_001230055	(Get FASTA)	NCBI Sequence Viewer
	NP_005037	(Get FASTA)	NCBI Sequence Viewer
	NP_644806	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC37551	(Get FASTA)	NCBI Sequence Viewer
	AAD49718	(Get FASTA)	NCBI Sequence Viewer
	AAG33360	(Get FASTA)	NCBI Sequence Viewer
	AAH32005	(Get FASTA)	NCBI Sequence Viewer
	AAK69624	(Get FASTA)	NCBI Sequence Viewer
	AAN03662	(Get FASTA)	NCBI Sequence Viewer
	AAN03663	(Get FASTA)	NCBI Sequence Viewer
	AAT66047	(Get FASTA)	NCBI Sequence Viewer
	AAU04540	(Get FASTA)	NCBI Sequence Viewer
	AAY97797	(Get FASTA)	NCBI Sequence Viewer
	AHN52223	(Get FASTA)	NCBI Sequence Viewer
	AHN52224	(Get FASTA)	NCBI Sequence Viewer
	AQM73456	(Get FASTA)	NCBI Sequence Viewer
	AQM73457	(Get FASTA)	NCBI Sequence Viewer
	BAF82349	(Get FASTA)	NCBI Sequence Viewer
	BAG58291	(Get FASTA)	NCBI Sequence Viewer
	CAA02644	(Get FASTA)	NCBI Sequence Viewer
	CAG17626	(Get FASTA)	NCBI Sequence Viewer
	EAW71958	(Get FASTA)	NCBI Sequence Viewer
	EAW71959	(Get FASTA)	NCBI Sequence Viewer
	EAW71960	(Get FASTA)	NCBI Sequence Viewer
	EAW71961	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000375683
	ENSP00000375683.1
	ENSP00000469950
	ENSP00000469950.1
	ENSP00000470538
	ENSP00000470538.1
GenBank Protein	P49862	(Get FASTA)	NCBI Sequence Viewer
	QIB02117	(Get FASTA)	NCBI Sequence Viewer
	QIB02118	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001193982 ⟸ NM_001207053
- Peptide Label:	isoform 2
- UniProtKB:	P49862 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNA CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR hide sequence

RefSeq Acc Id:	NP_005037 ⟸ NM_005046
- Peptide Label:	isoform 1 preproprotein
- UniProtKB:	Q8N5N9 (UniProtKB/Swiss-Prot), A8K0U5 (UniProtKB/Swiss-Prot), Q8NFV7 (UniProtKB/Swiss-Prot), P49862 (UniProtKB/Swiss-Prot), A0A024R4H6 (UniProtKB/TrEMBL), B8K1J4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERW VLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAG IPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR hide sequence

RefSeq Acc Id:	NP_644806 ⟸ NM_139277
- Peptide Label:	isoform 1 preproprotein
- UniProtKB:	Q8N5N9 (UniProtKB/Swiss-Prot), A8K0U5 (UniProtKB/Swiss-Prot), Q8NFV7 (UniProtKB/Swiss-Prot), P49862 (UniProtKB/Swiss-Prot), A0A024R4H6 (UniProtKB/TrEMBL), B8K1J4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERW VLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAG IPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR hide sequence

RefSeq Acc Id:	NP_001230055 ⟸ NM_001243126
- Peptide Label:	isoform 3
- UniProtKB:	P49862 (UniProtKB/Swiss-Prot), B4DHX9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKILEPSCVPAQVGTWITSDPLELQQERPFLAWQPLSGSAGHHGKIPSPAPADLTAILSLGNCR RRSEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN ACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR hide sequence

Ensembl Acc Id:

ENSP00000470538 ⟸ ENST00000595820

Protein Domains

Peptidase S1

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P49862-F1-model_v2	AlphaFold	P49862	1-253	view protein structure

RGD ID:

13205315

Promoter ID:

EPDNEW_H26238

Type:

initiation region

Name:

KLK7_2

Description:

kallikrein related peptidase 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H26239 EPDNEW_H26240 EPDNEW_H26241

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	50,983,915 - 50,983,975	EPDNEW

RGD ID:

13205317

Promoter ID:

EPDNEW_H26239

Type:

initiation region

Name:

KLK7_3

Description:

kallikrein related peptidase 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H26238 EPDNEW_H26240 EPDNEW_H26241

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	50,984,038 - 50,984,098	EPDNEW

RGD ID:

13205319

Promoter ID:

EPDNEW_H26240

Type:

initiation region

Name:

KLK7_4

Description:

kallikrein related peptidase 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H26238 EPDNEW_H26239 EPDNEW_H26241

Experiment Methods:

Single-end sequencing.; Paired-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	50,984,202 - 50,984,262	EPDNEW

Database	Acc Id	Source(s)
COSMIC	KLK7	COSMIC
Ensembl Genes	ENSG00000169035	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000391807	ENTREZGENE
	ENST00000391807.5	UniProtKB/Swiss-Prot
	ENST00000595820	ENTREZGENE
	ENST00000595820.6	UniProtKB/Swiss-Prot
	ENST00000597707	ENTREZGENE
	ENST00000597707.5	UniProtKB/Swiss-Prot
Gene3D-CATH	2.40.10.10	UniProtKB/Swiss-Prot
GTEx	ENSG00000169035	GTEx
HGNC ID	HGNC:6368	ENTREZGENE
Human Proteome Map	KLK7	Human Proteome Map
InterPro	Peptidase_S1_PA	UniProtKB/Swiss-Prot
	Peptidase_S1_PA_chymotrypsin	UniProtKB/Swiss-Prot
	Peptidase_S1A	UniProtKB/Swiss-Prot
	Trypsin_dom	UniProtKB/Swiss-Prot
	TRYPSIN_HIS	UniProtKB/Swiss-Prot
	TRYPSIN_SER	UniProtKB/Swiss-Prot
KEGG Report	hsa:5650	UniProtKB/Swiss-Prot
NCBI Gene	5650	ENTREZGENE
OMIM	604438	OMIM
PANTHER	KALLIKREIN-7	UniProtKB/Swiss-Prot
	KALLIKREIN-RELATED	UniProtKB/Swiss-Prot
Pfam	Trypsin	UniProtKB/Swiss-Prot
PharmGKB	PA30157	PharmGKB
PRINTS	CHYMOTRYPSIN	UniProtKB/Swiss-Prot
PROSITE	TRYPSIN_DOM	UniProtKB/Swiss-Prot
	TRYPSIN_HIS	UniProtKB/Swiss-Prot
	TRYPSIN_SER	UniProtKB/Swiss-Prot
SMART	Tryp_SPc	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50494	UniProtKB/Swiss-Prot
UniProt	A0A024R4H6	ENTREZGENE, UniProtKB/TrEMBL
	A0A2H4GDB2_HUMAN	UniProtKB/TrEMBL
	A0A2H4GDB6_HUMAN	UniProtKB/TrEMBL
	A8K0U5	ENTREZGENE
	B4DHX9	ENTREZGENE, UniProtKB/TrEMBL
	B8K1J4	ENTREZGENE, UniProtKB/TrEMBL
	KLK7_HUMAN	UniProtKB/Swiss-Prot
	M0QYU8_HUMAN	UniProtKB/TrEMBL
	P49862	ENTREZGENE
	Q6DTY1_HUMAN	UniProtKB/TrEMBL
	Q8N5N9	ENTREZGENE
	Q8NFV7	ENTREZGENE
	X2J289_HUMAN	UniProtKB/TrEMBL
	X2J4X7_HUMAN	UniProtKB/TrEMBL
UniProt Secondary	A8K0U5	UniProtKB/Swiss-Prot
	Q8N5N9	UniProtKB/Swiss-Prot
	Q8NFV7	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-17	KLK7	kallikrein related peptidase 7	KLK7	kallikrein-related peptidase 7	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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