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Gene: XPNPEP3 (X-prolyl aminopeptidase 3) Homo sapiens
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Symbol: XPNPEP3
Name: X-prolyl aminopeptidase 3
Description: Exhibits manganese ion binding activity; metalloaminopeptidase activity; and protein homodimerization activity. Involved in glomerular filtration and protein processing. Localizes to mitochondrion. Implicated in nephronophthisis-like nephropathy 1.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: aminopeptidase P3; APP3; ICP55; Intermediate Cleaving Peptidase 55; NPHPL1; probable Xaa-Pro aminopeptidase 3; X-Pro aminopeptidase 3; X-prolyl aminopeptidase (aminopeptidase P) 3, putative; X-prolyl aminopeptidase 3, mitochondrial; xaa-Pro aminopeptidase 3
Orthologs:
Mus musculus (house mouse) : Xpnpep3 (X-prolyl aminopeptidase 3, mitochondrial)  MGI  Alliance
Rattus norvegicus (Norway rat) : Xpnpep3 (X-prolyl aminopeptidase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xpnpep3 (X-prolyl aminopeptidase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : XPNPEP3 (X-prolyl aminopeptidase 3)
Canis lupus familiaris (dog) : XPNPEP3 (X-prolyl aminopeptidase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xpnpep3 (X-prolyl aminopeptidase 3)
Sus scrofa (pig) : XPNPEP3 (X-prolyl aminopeptidase 3)
Chlorocebus sabaeus (African green monkey) : XPNPEP3 (X-prolyl aminopeptidase 3)
Heterocephalus glaber (naked mole-rat) : Xpnpep3 (X-prolyl aminopeptidase 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2240,857,077 - 40,932,815 (+)EnsemblGRCh38hg38GRCh38
GRCh382240,857,081 - 40,932,815 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372241,253,085 - 41,328,823 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,583,040 - 39,653,829 (+)NCBINCBI36hg18NCBI36
Celera2225,056,765 - 25,127,557 (+)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2224,215,119 - 24,290,638 (+)NCBIHuRef
CHM1_12241,211,837 - 41,287,590 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on XPNPEP3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603202
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.