GWAS1408915_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS1408915_H (total cholesterol measurement QTL GWAS1408915 (human)) Homo sapiens

Symbol: GWAS1408915_H
Name: total cholesterol measurement QTL GWAS1408915 (human)
RGD ID: 597312841
Trait: total cholesterol measurement
Measurement Type: blood total cholesterol level   (CMO:0000051)    
LOD Score: Not Available
P Value: 4.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382240,918,008 - 40,918,009RGD_MAPPER_PIPELINEGRCh38
GRCh372241,314,012 - 41,314,013RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1408915_HHumanblood total cholesterol level  IAGPrs5758128405850206 GWAS_CATALOGPMID:34594039

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS1408915_HHumantotal cholesterol measurement  IAGPrs5758128405850206 GWAS_CATALOGPMID:34594039

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1603202XPNPEP3X-prolyl aminopeptidase 3224085714840932815Human


Peak: (rs5758128)
Human AssemblyChrPosition (strand)Source
GRCh382240,918,008 - 40,918,009RGD_MAPPER_PIPELINE


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597312841GWAS1408915_Htotal cholesterol measurement QTL GWAS1408915 (human)4e-08total cholesterol measurementblood total cholesterol level (CMO:0000051)224091800840918009Human
597041122GWAS1137196_Hlow density lipoprotein cholesterol measurement QTL GWAS1137196 (human)6e-13low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)224091800840918009Human



Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS1408915_H GCST90018974 Total cholesterol levels 344,278 European ancestry individuals, 135,808 East Asian ancestry individuals T NR 4E-8 7.398 rs5758128 0.0128 total cholesterol measurement (EFO:0004574)
 PMID:34594039
GWAS1137196_H GCST010204 Low density lipoprotein cholesterol levels 324,708 British ancestry individuals ? NR 6E-13 12.222 rs5758128 0.0186 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:32154731
Database
Acc Id
Source(s)
GWAS Catalog GCST90018974 GWAS Catalog

Note Type Note Reference