XPNPEP3 (X-prolyl aminopeptidase 3) - Rat Genome Database

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Gene: XPNPEP3 (X-prolyl aminopeptidase 3) Sus scrofa
Analyze
Symbol: XPNPEP3
Name: X-prolyl aminopeptidase 3
RGD ID: 14062698
Description: ENCODES a protein that exhibits aminopeptidase activity (inferred); hydrolase activity (inferred); manganese ion binding (inferred); INVOLVED IN glomerular filtration (ortholog); protein processing (ortholog); PARTICIPATES IN presequence pathway of mitochondrial protein import; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); common variable immunodeficiency 4 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable Xaa-Pro aminopeptidase 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl57,530,999 - 7,582,961 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.157,530,993 - 7,582,981 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
mitochondrion  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
XPNPEP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl57,530,999 - 7,582,961 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.157,530,993 - 7,582,981 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
XPNPEP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382240,857,148 - 40,932,815 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2240,857,077 - 40,932,815 (+)EnsemblGRCh38hg38GRCh38
GRCh372241,253,152 - 41,328,819 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,583,040 - 39,653,829 (+)NCBINCBI36Build 36hg18NCBI36
Celera2225,056,765 - 25,127,557 (+)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2224,215,119 - 24,290,638 (+)NCBIHuRef
CHM1_12241,211,837 - 41,287,590 (+)NCBICHM1_1
T2T-CHM13v2.02241,329,340 - 41,405,008 (+)NCBIT2T-CHM13v2.0
Xpnpep3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,284,282 - 81,341,683 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1581,284,339 - 81,341,683 (+)EnsemblGRCm39 Ensembl
GRCm381581,400,105 - 81,457,482 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,400,138 - 81,457,482 (+)EnsemblGRCm38mm10GRCm38
MGSCv371581,230,618 - 81,285,318 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361581,227,443 - 81,282,143 (+)NCBIMGSCv36mm8
Celera1583,518,225 - 83,572,893 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.08NCBI
Xpnpep3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87114,806,398 - 114,858,934 (+)NCBIGRCr8
mRatBN7.27112,926,154 - 112,978,793 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7112,926,248 - 112,974,878 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7114,688,588 - 114,737,270 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07116,912,089 - 116,960,769 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07116,881,498 - 116,930,179 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07122,636,252 - 122,686,983 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7122,636,171 - 122,688,819 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07122,612,798 - 122,661,434 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47119,729,428 - 119,779,023 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7109,245,696 - 109,321,789 (+)NCBICelera
Cytogenetic Map7q34NCBI
Xpnpep3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541326,507,860 - 26,566,826 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541326,507,860 - 26,564,105 (+)NCBIChiLan1.0ChiLan1.0
XPNPEP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22350,687,824 - 50,762,868 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12253,387,709 - 53,462,763 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02221,752,015 - 21,827,146 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12239,848,045 - 39,915,398 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2239,848,077 - 39,915,398 (+)Ensemblpanpan1.1panPan2
XPNPEP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11024,304,342 - 24,379,562 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1024,307,091 - 24,379,448 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1024,238,414 - 24,314,015 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01025,051,673 - 25,127,569 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1025,052,064 - 25,127,204 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11024,767,255 - 24,842,815 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01025,087,877 - 25,163,708 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01025,262,479 - 25,338,089 (-)NCBIUU_Cfam_GSD_1.0
Xpnpep3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049457,910,924 - 7,966,668 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936492919,689 - 976,910 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936492919,963 - 976,926 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XPNPEP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11923,413,111 - 23,473,293 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1923,413,215 - 23,473,170 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045102,090,595 - 102,161,675 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Xpnpep3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247527,574,920 - 7,634,838 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247527,573,399 - 7,634,875 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in XPNPEP3
2039 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1
Low 10 4 3 4 2 22 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000043980   ⟹   ENSSSCP00000034837
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl57,533,815 - 7,582,888 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000060667   ⟹   ENSSSCP00000033364
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl57,530,999 - 7,582,959 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000062118   ⟹   ENSSSCP00000040460
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl57,530,999 - 7,582,961 (-)Ensembl
RefSeq Acc Id: XM_021091465   ⟹   XP_020947124
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.157,530,993 - 7,582,980 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091466   ⟹   XP_020947125
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.157,530,993 - 7,582,871 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091467   ⟹   XP_020947126
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.157,530,993 - 7,582,963 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091468   ⟹   XP_020947127
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.157,530,993 - 7,582,981 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091469   ⟹   XP_020947128
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.157,530,993 - 7,582,961 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091470   ⟹   XP_020947129
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.157,530,993 - 7,582,961 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091471   ⟹   XP_020947130
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.157,530,993 - 7,582,963 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091472   ⟹   XP_020947131
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.157,530,993 - 7,569,516 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020947127   ⟸   XM_021091468
- Peptide Label: isoform X4
- UniProtKB: A0A286ZT65 (UniProtKB/TrEMBL),   A0A8D1MWJ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020947124   ⟸   XM_021091465
- Peptide Label: isoform X1
- UniProtKB: A0A8D1Y3G0 (UniProtKB/TrEMBL),   A0A480KMG1 (UniProtKB/TrEMBL),   A0A8D0I625 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020947126   ⟸   XM_021091467
- Peptide Label: isoform X3
- UniProtKB: A0A481AAL5 (UniProtKB/TrEMBL),   A0A8D2BLV6 (UniProtKB/TrEMBL),   A0A8D0VAR4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020947130   ⟸   XM_021091471
- Peptide Label: isoform X5
- UniProtKB: A0A287A9A6 (UniProtKB/TrEMBL),   A0A8D2C346 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020947129   ⟸   XM_021091470
- Peptide Label: isoform X5
- UniProtKB: A0A287A9A6 (UniProtKB/TrEMBL),   A0A8D2C346 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020947128   ⟸   XM_021091469
- Peptide Label: isoform X5
- UniProtKB: A0A287A9A6 (UniProtKB/TrEMBL),   A0A8D2C346 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020947125   ⟸   XM_021091466
- Peptide Label: isoform X2
- UniProtKB: A0A8D1ABS6 (UniProtKB/TrEMBL),   A0A286ZP46 (UniProtKB/TrEMBL),   A0A8D2BLV6 (UniProtKB/TrEMBL),   A0A8D0VAR4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020947131   ⟸   XM_021091472
- Peptide Label: isoform X5
- UniProtKB: A0A287A9A6 (UniProtKB/TrEMBL),   A0A8D2C346 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000033364   ⟸   ENSSSCT00000060667
RefSeq Acc Id: ENSSSCP00000040460   ⟸   ENSSSCT00000062118
RefSeq Acc Id: ENSSSCP00000034837   ⟸   ENSSSCT00000043980
Protein Domains
Aminopeptidase P N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000033823 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005004403 UniProtKB/TrEMBL
  ENSSSCG00015062127 UniProtKB/TrEMBL
  ENSSSCG00025010768 UniProtKB/TrEMBL
  ENSSSCG00030005333 UniProtKB/TrEMBL
  ENSSSCG00035051950 UniProtKB/TrEMBL
  ENSSSCG00040019545 UniProtKB/TrEMBL
  ENSSSCG00045029189 UniProtKB/TrEMBL
  ENSSSCG00050052942 UniProtKB/TrEMBL
  ENSSSCG00055016147 UniProtKB/TrEMBL
  ENSSSCG00060049772 UniProtKB/TrEMBL
  ENSSSCG00065026609 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000043980.2 UniProtKB/TrEMBL
  ENSSSCT00000060667 ENTREZGENE
  ENSSSCT00000060667.3 UniProtKB/TrEMBL
  ENSSSCT00000062118 ENTREZGENE
  ENSSSCT00000062118.3 UniProtKB/TrEMBL
  ENSSSCT00005006513.1 UniProtKB/TrEMBL
  ENSSSCT00005006557.1 UniProtKB/TrEMBL
  ENSSSCT00005006593.1 UniProtKB/TrEMBL
  ENSSSCT00005006644.1 UniProtKB/TrEMBL
  ENSSSCT00005006688.1 UniProtKB/TrEMBL
  ENSSSCT00015082951.1 UniProtKB/TrEMBL
  ENSSSCT00015083287.1 UniProtKB/TrEMBL
  ENSSSCT00015083610.1 UniProtKB/TrEMBL
  ENSSSCT00025014120.1 UniProtKB/TrEMBL
  ENSSSCT00025014138.1 UniProtKB/TrEMBL
  ENSSSCT00025014155.1 UniProtKB/TrEMBL
  ENSSSCT00030007264.1 UniProtKB/TrEMBL
  ENSSSCT00030007266.1 UniProtKB/TrEMBL
  ENSSSCT00030007269.1 UniProtKB/TrEMBL
  ENSSSCT00035069216.1 UniProtKB/TrEMBL
  ENSSSCT00035069227.1 UniProtKB/TrEMBL
  ENSSSCT00035069234.1 UniProtKB/TrEMBL
  ENSSSCT00035069237.1 UniProtKB/TrEMBL
  ENSSSCT00040026372.1 UniProtKB/TrEMBL
  ENSSSCT00040026403.1 UniProtKB/TrEMBL
  ENSSSCT00040026428.1 UniProtKB/TrEMBL
  ENSSSCT00045049781.1 UniProtKB/TrEMBL
  ENSSSCT00045049908.1 UniProtKB/TrEMBL
  ENSSSCT00045050018.1 UniProtKB/TrEMBL
  ENSSSCT00050072097.1 UniProtKB/TrEMBL
  ENSSSCT00050072103.1 UniProtKB/TrEMBL
  ENSSSCT00055031795.1 UniProtKB/TrEMBL
  ENSSSCT00055031902.1 UniProtKB/TrEMBL
  ENSSSCT00055031952.1 UniProtKB/TrEMBL
  ENSSSCT00060067613.1 UniProtKB/TrEMBL
  ENSSSCT00060067620.1 UniProtKB/TrEMBL
  ENSSSCT00060067626.1 UniProtKB/TrEMBL
  ENSSSCT00065035779.1 UniProtKB/TrEMBL
  ENSSSCT00065035782.1 UniProtKB/TrEMBL
  ENSSSCT00065035787.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.350.10 UniProtKB/TrEMBL
  3.90.230.10 UniProtKB/TrEMBL
InterPro Aminopep_P_N UniProtKB/TrEMBL
  Creatin/AminoP/Spt16_NTD UniProtKB/TrEMBL
  Creatinase/aminopeptidase-like UniProtKB/TrEMBL
  Pept_M24 UniProtKB/TrEMBL
NCBI Gene XPNPEP3 ENTREZGENE
PANTHER XAA-PRO AMINOPEPTIDASE 3 UniProtKB/TrEMBL
  XAA-PRO AMINOPEPTIDASE 3 UniProtKB/TrEMBL
Pfam AMP_N UniProtKB/TrEMBL
  Peptidase_M24 UniProtKB/TrEMBL
SMART AMP_N UniProtKB/TrEMBL
Superfamily-SCOP SSF53092 UniProtKB/TrEMBL
  SSF55920 UniProtKB/TrEMBL
UniProt A0A286ZP46 ENTREZGENE, UniProtKB/TrEMBL
  A0A286ZT65 ENTREZGENE, UniProtKB/TrEMBL
  A0A287A9A6 ENTREZGENE, UniProtKB/TrEMBL
  A0A480KMG1 ENTREZGENE, UniProtKB/TrEMBL
  A0A481AAL5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0HYP5_PIG UniProtKB/TrEMBL
  A0A8D0I625 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0LEF9_PIG UniProtKB/TrEMBL
  A0A8D0LF11_PIG UniProtKB/TrEMBL
  A0A8D0VAR4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1ABR7_PIG UniProtKB/TrEMBL
  A0A8D1ABS6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1DQR4_PIG UniProtKB/TrEMBL
  A0A8D1DR20_PIG UniProtKB/TrEMBL
  A0A8D1MWJ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Y3G0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2BLV6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2C346 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:95002 ENTREZGENE