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Gene: ADAMTS1 (ADAM metallopeptidase with thrombospondin type 1 motif 1) Homo sapiens
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Symbol: ADAMTS1
Name: ADAM metallopeptidase with thrombospondin type 1 motif 1
RGD ID: 736845
Description: Exhibits metalloendopeptidase activity. Involved in several processes, including positive regulation of G1/S transition of mitotic cell cycle; positive regulation of vascular associated smooth muscle cell migration; and positive regulation of vascular associated smooth muscle cell proliferation. Colocalizes with collagen-containing extracellular matrix.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A disintegrin and metalloproteinase with thrombospondin motifs 1; a disintegrin and metalloproteinase with thrombospondin motifs 1 (adamts-1); a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM metallopeptidase with thrombospondin type 1 motif, 1; ADAM-TS 1; ADAM-TS1; ADAMTS-1; C3-C5; human metalloproteinase with thrombospondin type 1 motifs; KIAA1346; METH-1; METH1
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2126,835,755 - 26,845,409 (-)EnsemblGRCh38hg38GRCh38
GRCh382126,835,755 - 26,845,409 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372128,208,606 - 28,217,728 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362127,130,477 - 27,139,599 (-)NCBINCBI36hg18NCBI36
Build 342127,130,478 - 27,139,599NCBI
Celera2113,391,944 - 13,401,066 (-)NCBI
Cytogenetic Map21q21.3NCBI
HuRef2113,613,149 - 13,622,273 (-)NCBIHuRef
CHM1_12127,770,054 - 27,779,178 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ADAMTS1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736845
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.