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Gene: AEBP1 (AE binding protein 1) Homo sapiens
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Symbol: AEBP1
Name: AE binding protein 1
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and collagen binding activity. Involved in negative regulation of transcription by RNA polymerase II and regulation of collagen fibril organization. Localizes to the collagen-containing extracellular matrix and extracellular exosome. Implicated in Ehlers-Danlos syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACLP; adipocyte enhancer binding protein 1; adipocyte enhancer-binding protein 1; AE-binding protein 1; aortic carboxypeptidase-like protein; FLJ33612
Orthologs:
Mus musculus (house mouse) : Aebp1 (AE binding protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aebp1 (AE binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aebp1 (AE binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AEBP1 (AE binding protein 1)
Canis lupus familiaris (dog) : AEBP1 (AE binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aebp1 (AE binding protein 1)
Sus scrofa (pig) : AEBP1 (AE binding protein 1)
Chlorocebus sabaeus (African green monkey) : AEBP1 (AE binding protein 1)
Heterocephalus glaber (naked mole-rat) : Aebp1 (AE binding protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl744,104,345 - 44,114,562 (+)EnsemblGRCh38hg38GRCh38
GRCh38744,104,320 - 44,114,564 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37744,143,960 - 44,154,164 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,110,485 - 44,120,684 (+)NCBINCBI36hg18NCBI36
Build 34743,917,199 - 43,927,398NCBI
Celera744,241,911 - 44,252,113 (+)NCBI
Cytogenetic Map7p13NCBI
HuRef744,029,222 - 44,039,430 (+)NCBIHuRef
CHM1_1744,147,805 - 44,158,013 (+)NCBICHM1_1
CRA_TCAGchr7v2744,183,452 - 44,193,659 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on AEBP1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1315812
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.