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Gene: LAP3 (leucine aminopeptidase 3) Homo sapiens
Symbol: LAP3
Name: leucine aminopeptidase 3
Description: Predicted to have peptidase activity. Predicted to be involved in proteolysis. Localizes to cytosol; midbody; and nucleoplasm; PARTICIPATES IN arginine and proline metabolic pathway; glutathione metabolic pathway; INTERACTS WITH aflatoxin B1; antirheumatic drug; arsenous acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cytosol aminopeptidase; epididymis secretory protein Li 106; HEL-S-106; LAP; LAP-3; LAPEP; leucyl aminopeptidase; PEPS; peptidase S; proline aminopeptidase; prolyl aminopeptidase
Mus musculus (house mouse) : Lap3 (leucine aminopeptidase 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lap3 (leucine aminopeptidase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lap3 (leucine aminopeptidase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : LAP3 (leucine aminopeptidase 3)
Canis lupus familiaris (dog) : LAP3 (leucine aminopeptidase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lap3 (leucine aminopeptidase 3)
Sus scrofa (pig) : LAP3 (leucine aminopeptidase 3)
Chlorocebus sabaeus (African green monkey) : LAP3 (leucine aminopeptidase 3)
Heterocephalus glaber (naked mole-rat) : Lap3 (leucine aminopeptidase 3)
more info ...
Related Pseudogenes: LAP3P1   LAP3P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl417,577,192 - 17,607,972 (+)EnsemblGRCh38hg38GRCh38
GRCh38417,577,304 - 17,607,967 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37417,578,927 - 17,609,590 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36417,188,025 - 17,218,688 (+)NCBINCBI36hg18NCBI36
Build 34417,255,195 - 17,285,859NCBI
Celera418,043,925 - 18,074,586 (+)NCBI
Cytogenetic Map4p15.32NCBI
HuRef416,933,825 - 16,964,179 (+)NCBIHuRef
CHM1_1417,576,837 - 17,607,598 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on LAP3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317491
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.