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ONTOLOGY REPORT - ANNOTATIONS


Term:chloride channel activity
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Accession:GO:0005254 term browser browse the term
Definition:Enables the energy-independent facilitated diffusion of a chloride ion through a transmembrane aqueous pore or channel.
Synonyms:xref: Reactome:R-HSA-2684901 "ANOs transport cytosolic Cl- to extracellular region";   Reactome:R-HSA-2744242 "TTYH2/3 transport cytosolic Cl- to extracellular region";   Reactome:R-HSA-2744361 "BESTs transport cytosolic Cl- to extracellular region";   Reactome:R-HSA-9659568 "ANO1 transports cytosolic Cl- to extracellular region";   Reactome:R-HSA-9712204 "ANO2:Ca2+ translocates Cl- from the cytosol to the extracellular region";   Reactome:R-HSA-975449 "GABRR pentamers:GABA transports extracellular Cl- to cytosol";   reactome:R-HSA-2744349 "TTYH1 transports cytosolic Cl- to extracellular region";   reactome:R-HSA-427570 "Group 3 - Selective Cl- transport";   reactome:R-HSA-975340 "GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol"



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chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Ano1 anoctamin 1 enables ISO (PMID:24885604), (PMID:28963502), (PMID:32487539)
(PMID:24885604), (PMID:25779870), (PMID:28963502), (PMID:31147466)
RGD PMID:24885604 PMID:25779870 PMID:28963502 PMID:31147466 PMID:32487539 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
JBrowse link
G Ano10 anoctamin 10 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:121,841,664...121,960,739
Ensembl chr 8:121,841,665...121,962,670
JBrowse link
G Ano3 anoctamin 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:97,235,671...97,550,090
Ensembl chr 3:97,238,354...97,550,154
JBrowse link
G Ano5 anoctamin 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:101,086,490...101,187,547
Ensembl chr 1:101,087,341...101,187,555
JBrowse link
G Ano6 anoctamin 6 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:126,933,919...127,113,588
Ensembl chr 7:126,933,936...127,113,589
JBrowse link
G Ano7 anoctamin 7 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:93,917,524...93,945,323
Ensembl chr 9:93,917,524...93,945,323
JBrowse link
G Ano8 anoctamin 8 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:18,163,853...18,173,248
Ensembl chr16:18,163,843...18,173,545
JBrowse link
G Ano9 anoctamin 9 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:196,208,863...196,230,381
Ensembl chr 1:196,197,341...196,229,900
JBrowse link
G Best1 bestrophin 1 contributes_to
enables
ISO (PMID:17003041) RGD PMID:17003041 NCBI chr 1:206,629,340...206,646,085
Ensembl chr 1:206,629,500...206,646,063
JBrowse link
G Best2 bestrophin 2 enables
contributes_to
ISO (PMID:18400985)
(PMID:16707793), (PMID:18400985)
(PMID:16912113)
RGD PMID:16707793 PMID:16912113 PMID:18400985 NCBI chr19:23,142,324...23,148,351
Ensembl chr19:23,141,602...23,148,339
JBrowse link
G Best3 bestrophin 3 enables ISO (PMID:16563389) RGD PMID:16563389 NCBI chr 7:52,586,824...52,656,776
Ensembl chr 7:52,615,776...52,656,766
JBrowse link
G Best4 bestrophin 4 enables ISO (PMID:18400985) RGD PMID:18400985 NCBI chr 5:130,622,194...130,629,045
Ensembl chr 5:130,623,438...130,627,099
JBrowse link
G Bsnd barttin CLCNK type accessory subunit beta contributes_to ISS
ISO
GO_REF:0000024
(PMID:11734858)
UniProt
RGD
PMID:11734858 GO_REF:0000024 NCBI chr 5:121,251,774...121,260,571
Ensembl chr 5:121,251,774...121,260,571
JBrowse link
G Cftr CF transmembrane conductance regulator enables ISO
IEA
ISS
(PMID:11524016), (PMID:11707463), (PMID:15010471), (PMID:18570918), (PMID:19019741), (PMID:19621064), (PMID:22178883), (PMID:24885604)
(PMID:20231442), (PMID:24885604)
GO_REF:0000043
GO_REF:0000002
GO_REF:0000024
RGD
UniProt
InterPro
PMID:11524016 PMID:11707463 PMID:15010471 PMID:18570918 PMID:19019741 More... GO_REF:0000002 GO_REF:0000024 GO_REF:0000043 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Clca2 chloride channel accessory 2 enables ISO (PMID:15284223) RGD PMID:15284223 NCBI chr 2:233,993,619...234,022,691
Ensembl chr 2:233,995,078...234,022,199
JBrowse link
G Clca4 chloride channel accessory 4 enables ISO (PMID:15284223) RGD PMID:15284223 NCBI chr 2:233,883,625...233,904,993
Ensembl chr 2:233,883,851...233,903,089
JBrowse link
G Clcc1 chloride channel CLIC-like 1 enables IDA
ISO
IEA
IBA
IMP
(PMID:37142673)
GO_REF:0000107
GO_REF:0000033
PMID:11279057
RGD
Ensembl
GO_Central
PMID:37142673 PMID:11279057 PMID:11279057 GO_REF:0000033 GO_REF:0000107, RGD:1299391, RGD:1299391 NCBI chr 2:196,296,350...196,326,914
Ensembl chr 2:196,296,393...196,326,913
JBrowse link
G Clcn3 chloride voltage-gated channel 3 enables IDA
ISO
(PMID:11274166) RGD PMID:11274166 PMID:10915634 RGD:628537 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Clcn4 chloride voltage-gated channel 4 enables ISO (PMID:10564087) RGD PMID:10564087 NCBI chr  X:23,729,194...23,795,391
Ensembl chr  X:23,729,338...23,793,238
JBrowse link
G Clcnka chloride voltage-gated channel Ka enables IDA
ISO
(PMID:23791703)
(PMID:12111250)
RGD PMID:12111250 PMID:23791703 PMID:7680033 PMID:12111250 RGD:68767, RGD:632278 NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148
JBrowse link
G Clcnkb chloride voltage-gated channel Kb enables IDA
ISO
(PMID:27335120)
(PMID:12111250)
RGD PMID:12111250 PMID:27335120 PMID:8021279 RGD:1600680 NCBI chr 5:153,710,086...153,733,162
Ensembl chr 5:153,710,094...153,732,153
JBrowse link
G Clic1 chloride intracellular channel 1 enables ISO
IBA
IEA
(PMID:9139710)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000043
RGD
GO_Central
Ensembl
UniProt
PMID:9139710 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
JBrowse link
G Clic2 chloride intracellular channel 2 enables IEA
IBA
GO_REF:0000043
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000043 NCBI chr20:149,337...164,375
Ensembl chr20:148,907...164,355
JBrowse link
G Clic3 chloride intracellular channel 3 enables ISO
IBA
(PMID:9880541)
GO_REF:0000033
RGD
GO_Central
PMID:9880541 GO_REF:0000033 NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018
JBrowse link
G Clic4 chloride intracellular channel 4 enables IDA
IBA
IEA
GO_REF:0000033
GO_REF:0000043
GO_Central
UniProt
RGD
PMID:12237120 GO_REF:0000033 GO_REF:0000043, RGD:632350 NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
JBrowse link
G Clic5 chloride intracellular channel 5 enables IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:8537381 GO_REF:0000033, RGD:727234 NCBI chr 9:16,710,980...16,813,502
Ensembl chr 9:16,710,980...16,813,427
JBrowse link
G Clic6 chloride intracellular channel 6 enables ISO
IEA
ISS
(PMID:37838179)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:37838179 GO_REF:0000024 GO_REF:0000107 NCBI chr11:31,737,813...31,780,360
Ensembl chr11:31,737,813...31,780,061
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 contributes_to
enables
IBA
IEA
GO_REF:0000033
GO_REF:0000043
GO_Central
UniProt
GO_REF:0000033 GO_REF:0000043 NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944
JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:150,244,745...150,501,566
Ensembl chr  X:150,261,607...150,501,559
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 contributes_to TAS
IBA
GO_REF:0000033 GO_Central
RGD
PMID:2153588 GO_REF:0000033, RGD:61593 NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 contributes_to
enables
IBA
IEA
GO_REF:0000033
GO_REF:0000043
GO_Central
UniProt
GO_REF:0000033 GO_REF:0000043 NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 enables IMP
IEA
PMID:18281286
GO_REF:0000043
UniProt PMID:18281286 GO_REF:0000043, RGD:8693370 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 enables IDA
IEA
GO_REF:0000043 UniProt
RGD
PMID:12356876 GO_REF:0000043, RGD:727440 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
JBrowse link
G Gabrd gamma-aminobutyric acid type A receptor subunit delta enables
contributes_to
IEA
IBA
GO_REF:0000043
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000043 NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411
JBrowse link
G Gabre gamma-aminobutyric acid type A receptor subunit epsilon contributes_to
enables
IBA
IEA
GO_REF:0000033
GO_REF:0000043
GO_Central
UniProt
GO_REF:0000033 GO_REF:0000043 NCBI chr  X:150,060,035...150,078,773
Ensembl chr  X:150,060,040...150,078,693
JBrowse link
G Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 contributes_to
enables
IBA
IEA
GO_REF:0000033
GO_REF:0000043
GO_Central
UniProt
GO_REF:0000033 GO_REF:0000043 NCBI chr14:37,396,217...37,469,606
Ensembl chr14:37,396,294...37,635,956
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 enables IDA
ISO
(PMID:18281286) RGD PMID:18281286 PMID:2561970 RGD:61596 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 enables IDA
IEA
GO_REF:0000043 UniProt
RGD
PMID:1311098 GO_REF:0000043, RGD:727524 NCBI chr 1:107,627,450...108,247,483
Ensembl chr 1:107,627,390...108,246,763
JBrowse link
G Gabrp gamma-aminobutyric acid type A receptor subunit pi contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:18,143,031...18,169,595
Ensembl chr10:18,143,038...18,169,516
JBrowse link
G Gabrq gamma-aminobutyric acid type A receptor subunit theta contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:150,696,161...150,712,948
Ensembl chr  X:150,696,427...150,709,919
JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 enables
contributes_to
IEA
IBA
GO_REF:0000043
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000043 NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228
JBrowse link
G Gabrr2 gamma-aminobutyric acid type A receptor subunit rho 2 contributes_to TAS
IBA
GO_REF:0000033 GO_Central
RGD
PMID:11891787 GO_REF:0000033, RGD:728465 NCBI chr 5:47,445,280...47,489,929
Ensembl chr 5:47,452,150...47,489,809
JBrowse link
G Gabrr3 gamma-aminobutyric acid type A receptor subunit rho3 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:40,902,812...40,955,263
Ensembl chr11:40,902,812...40,955,263
JBrowse link
G Glra1 glycine receptor, alpha 1 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
JBrowse link
G Glra2 glycine receptor, alpha 2 enables
contributes_to
IEA
IBA
GO_REF:0000043
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000043 NCBI chr  X:29,020,377...29,241,666
Ensembl chr  X:29,020,557...29,241,666
JBrowse link
G Glra3 glycine receptor, alpha 3 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:34,199,937...34,848,773
Ensembl chr16:34,204,811...34,848,753
JBrowse link
G Glra4 glycine receptor alpha 4 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:100,110,517...100,131,042
Ensembl chr  X:100,110,517...100,131,042
JBrowse link
G Glrb glycine receptor, beta contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:166,134,616...166,207,498
Ensembl chr 2:166,134,626...166,207,489
JBrowse link
G Mfsd8 major facilitator superfamily domain containing 8 enables ISO
IBA
(PMID:34910516)
GO_REF:0000033
RGD
GO_Central
PMID:34910516 GO_REF:0000033 NCBI chr 2:123,822,042...123,847,808
Ensembl chr 2:123,816,614...123,857,971
JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein enables ISO (PMID:25513726) RGD PMID:25513726 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074
JBrowse link
G Pacc1 proton activated chloride channel 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:102,904,668...102,929,770
Ensembl chr13:102,894,612...102,929,770
JBrowse link
G Slc17a6 solute carrier family 17 member 6 enables IDA
IEA
PMID:27133463
GO_REF:0000043
UniProt PMID:27133463 GO_REF:0000043, RGD:152025528 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542
JBrowse link
G Slc17a7 solute carrier family 17 member 7 enables ISS
ISO
IDA
GO_REF:0000024
(PMID:25433636), (PMID:29273736)
PMID:10938000
PMID:19169251
UniProt
RGD
PMID:25433636 PMID:29273736 PMID:10938000 PMID:19169251 GO_REF:0000024, RGD:12050146, RGD:152025512 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
JBrowse link
G Slc17a8 solute carrier family 17 member 8 enables IDA PMID:27133463 UniProt PMID:27133463 RGD:152025528 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079
JBrowse link
G Slc1a4 solute carrier family 1 member 4 enables ISO (PMID:8910405) RGD PMID:8910405 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
JBrowse link
G Slc26a11 solute carrier family 26 member 11 enables ISO (PMID:23733100) RGD PMID:23733100 NCBI chr10:104,613,498...104,635,873
Ensembl chr10:104,613,564...104,635,970
JBrowse link
G Slc26a7 solute carrier family 26 member 7 enables ISO (PMID:11834742)
(PMID:15591059), (PMID:24810589)
RGD PMID:11834742 PMID:15591059 PMID:24810589 NCBI chr 5:27,884,400...28,021,865
Ensembl chr 5:27,887,042...28,021,658
JBrowse link
G Slc26a8 solute carrier family 26 member 8 enables ISO (PMID:11834742) RGD PMID:11834742 NCBI chr20:6,686,206...6,749,478
Ensembl chr20:6,697,723...6,749,478
JBrowse link
G Slc26a9 solute carrier family 26 member 9 enables ISO (PMID:17673510), (PMID:18769029), (PMID:19289574), (PMID:20658517), (PMID:22544634), (PMID:32818062)
(PMID:31339488)
RGD PMID:17673510 PMID:18769029 PMID:19289574 PMID:20658517 PMID:22544634 More... NCBI chr13:43,177,806...43,205,450
Ensembl chr13:43,177,867...43,204,330
JBrowse link
G Ttyh1 tweety family member 1 NOT|enables ISO
IEA
(PMID:34385445)
GO_REF:0000104
RGD
UniProt
PMID:34385445 GO_REF:0000104 NCBI chr 1:70,053,312...70,071,872
Ensembl chr 1:70,053,324...70,071,845
JBrowse link
G Ttyh2 tweety family member 2 NOT|enables ISO (PMID:34385445) RGD PMID:34385445 NCBI chr10:99,709,063...99,753,449
Ensembl chr10:99,709,007...99,753,444
JBrowse link
G Ttyh3 tweety family member 3 enables
NOT|enables
ISO (PMID:15010458)
(PMID:34385445)
RGD PMID:15010458 PMID:34385445 NCBI chr12:13,996,831...14,025,457
Ensembl chr12:13,997,045...14,025,459
JBrowse link
extracellularly glutamate-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc17a7 solute carrier family 17 member 7 enables ISO (PMID:19169251) RGD PMID:19169251 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
JBrowse link
G Slc1a7 solute carrier family 1 member 7 enables ISO (PMID:16973698), (PMID:32233906) RGD PMID:16973698 PMID:32233906 NCBI chr 5:122,731,003...122,775,139
Ensembl chr 5:122,731,003...122,775,134
JBrowse link
extracellularly glycine-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glra1 glycine receptor, alpha 1 enables IDA
ISO
IEA
ISS
MGI:1856177|MGI:1856362 (PMID:16672662), (PMID:24801766), (PMID:8062927)
GO_REF:0000107
GO_REF:0000002
(PMID:16144831), (PMID:2155780), (PMID:7920629), (PMID:8137830)
RGD
Ensembl
InterPro
PMID:2155780 PMID:7920629 PMID:8062927 PMID:8137830 PMID:16144831 More... GO_REF:0000002 GO_REF:0000107, RGD:625689, RGD:8553668 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
JBrowse link
G Glra2 glycine receptor, alpha 2 enables TAS
IEA
ISO
GO_REF:0000002
GO_REF:0000107
(PMID:2155780)
InterPro
Ensembl
RGD
PMID:2155780 PMID:1645300 GO_REF:0000002 GO_REF:0000107, RGD:728718 NCBI chr  X:29,020,377...29,241,666
Ensembl chr  X:29,020,557...29,241,666
JBrowse link
G Glra3 glycine receptor, alpha 3 enables IDA
IEA
ISO
GO_REF:0000107
PMID:23895467
(PMID:26416729)
Ensembl
RGD
PMID:26416729 PMID:2176214 PMID:23895467 GO_REF:0000107, RGD:728440, RGD:11035333 NCBI chr16:34,199,937...34,848,773
Ensembl chr16:34,204,811...34,848,753
JBrowse link
G Glra4 glycine receptor alpha 4 enables ISO (PMID:10762330) RGD PMID:10762330 NCBI chr  X:100,110,517...100,131,042
Ensembl chr  X:100,110,517...100,131,042
JBrowse link
G Glrb glycine receptor, beta contributes_to
enables
ISO
IEA
ISS
(PMID:8717357)
MGI:1856363 (PMID:12809985), (PMID:16672662)
GO_REF:0000002
RGD
InterPro
PMID:8717357 PMID:12809985 PMID:16672662 PMID:8717357 GO_REF:0000002, RGD:8554374 NCBI chr 2:166,134,616...166,207,498
Ensembl chr 2:166,134,626...166,207,489
JBrowse link
GABA-gated chloride ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 contributes_to
enables
ISS
IBA
ISO
IDA
IEA
GO_REF:0000024
GO_REF:0000033
(PMID:27129275)
PMID:9882711
(PMID:2538761), (PMID:30602789), (PMID:9039914)
GO_REF:0000107
(PMID:23909897)
UniProt
GO_Central
RGD
Ensembl
PMID:2538761 PMID:9039914 PMID:23909897 PMID:27129275 PMID:30602789 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:405650244 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 enables ISO
IBA
IEA
(PMID:9039914)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:9039914 GO_REF:0000033 GO_REF:0000107 NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944
JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 enables ISS
IBA
IDA
ISO
IEA
GO_REF:0000024
GO_REF:0000033
PMID:9882711
(PMID:16412217), (PMID:29053855)
GO_REF:0000107
UniProt
GO_Central
RGD
Ensembl
PMID:16412217 PMID:29053855 PMID:9882711 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:405650244 NCBI chr  X:150,244,745...150,501,566
Ensembl chr  X:150,261,607...150,501,559
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 enables ISS
IBA
ISO
IDA
GO_REF:0000024
GO_REF:0000033
(PMID:14993607)
PMID:10462548
UniProt
GO_Central
RGD
PMID:14993607 PMID:10462548 GO_REF:0000024 GO_REF:0000033, RGD:405650343 NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 contributes_to IMP RGD PMID:17395622 RGD:1626515 NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 enables ISS
ISO
GO_REF:0000024
(PMID:16412217), (PMID:2538761), (PMID:26950270), (PMID:9039914)
UniProt
RGD
PMID:2538761 PMID:9039914 PMID:16412217 PMID:26950270 GO_REF:0000024 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 contributes_to
enables
ISS
ISO
IEA
GO_REF:0000024
(PMID:27129275)
GO_REF:0000107
(PMID:23909897)
UniProt
RGD
Ensembl
PMID:23909897 PMID:27129275 GO_REF:0000024 GO_REF:0000107 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 contributes_to
enables
ISS
ISO
IDA
IEA
GO_REF:0000024
(PMID:27129275)
(PMID:9108119)
PMID:10462548
(PMID:22303015), (PMID:26950270), (PMID:30602789), (PMID:9039914)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:9039914 PMID:9108119 PMID:22303015 PMID:26950270 PMID:27129275 More... GO_REF:0000024 GO_REF:0000107, RGD:405650343 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
JBrowse link
G Gabre gamma-aminobutyric acid type A receptor subunit epsilon enables ISO
IBA
ISS
(PMID:16412217), (PMID:9039914), (PMID:9882711)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:9039914 PMID:9882711 PMID:16412217 GO_REF:0000024 GO_REF:0000033 NCBI chr  X:150,060,035...150,078,773
Ensembl chr  X:150,060,040...150,078,693
JBrowse link
G Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:37,396,217...37,469,606
Ensembl chr14:37,396,294...37,635,956
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 contributes_to
enables
ISS
IBA
ISO
IEA
GO_REF:0000024
GO_REF:0000033
(PMID:27129275)
(PMID:2538761), (PMID:30602789)
GO_REF:0000107
(PMID:23909897)
UniProt
GO_Central
RGD
Ensembl
PMID:2538761 PMID:23909897 PMID:27129275 PMID:30602789 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 enables IDA
IBA
PMID:10462548
GO_REF:0000033
GO_Central PMID:10462548 GO_REF:0000033, RGD:405650343 NCBI chr 1:107,627,450...108,247,483
Ensembl chr 1:107,627,390...108,246,763
JBrowse link
G Gabrp gamma-aminobutyric acid type A receptor subunit pi enables ISO
IEA
IMP
ISS
(PMID:10462548)
GO_REF:0000107
PMID:17003036
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:10462548 PMID:17003036 GO_REF:0000024 GO_REF:0000107, RGD:405650305 NCBI chr10:18,143,031...18,169,595
Ensembl chr10:18,143,038...18,169,516
JBrowse link
G Gabrq gamma-aminobutyric acid type A receptor subunit theta enables ISO (PMID:16412217) RGD PMID:16412217 NCBI chr  X:150,696,161...150,712,948
Ensembl chr  X:150,696,427...150,709,919
JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 enables IDA PMID:8524843 UniProt PMID:8524843 RGD:728796 NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228
JBrowse link
G Gabrr2 gamma-aminobutyric acid type A receptor subunit rho 2 enables IDA PMID:8524843 UniProt PMID:8524843 RGD:728796 NCBI chr 5:47,445,280...47,489,929
Ensembl chr 5:47,452,150...47,489,809
JBrowse link
G Gabrr3 gamma-aminobutyric acid type A receptor subunit rho3 enables IDA PMID:11861315 UniProt PMID:11861315 RGD:405650323 NCBI chr11:40,902,812...40,955,263
Ensembl chr11:40,902,812...40,955,263
JBrowse link
glycine-gated chloride ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glra2 glycine receptor, alpha 2 enables ISO
IEA
(PMID:23895467)
GO_REF:0000107
RGD
Ensembl
PMID:23895467 GO_REF:0000107 NCBI chr  X:29,020,377...29,241,666
Ensembl chr  X:29,020,557...29,241,666
JBrowse link
G Glra3 glycine receptor, alpha 3 enables ISO
IEA
ISS
(PMID:9677400)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:9677400 GO_REF:0000024 GO_REF:0000107 NCBI chr16:34,199,937...34,848,773
Ensembl chr16:34,204,811...34,848,753
JBrowse link
intracellularly ATP-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator enables ISO
IEA
ISS
(PMID:8910473)
GO_REF:0000003
GO_REF:0000024
RGD
UniProt
PMID:8910473 GO_REF:0000003 GO_REF:0000024 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
intracellularly calcium-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano1 anoctamin 1 enables IMP
ISO
IBA
IDA
(PMID:18724360), (PMID:20056604), (PMID:22075693), (PMID:22634729), (PMID:23532839), (PMID:23576756), (PMID:28561733)
(PMID:21984732), (PMID:22178883), (PMID:22946059), (PMID:37253099)
GO_REF:0000033
PMID:25201006
RGD
GO_Central
PMID:18724360 PMID:20056604 PMID:21984732 PMID:22075693 PMID:22178883 More... GO_REF:0000033, RGD:9684846, RGD:10047211, RGD:9684847 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
JBrowse link
G Ano10 anoctamin 10 enables
NOT|enables
ISO (PMID:22946059)
(PMID:23532839)
(PMID:21984732)
RGD PMID:21984732 PMID:22946059 PMID:23532839 NCBI chr 8:121,841,664...121,960,739
Ensembl chr 8:121,841,665...121,962,670
JBrowse link
G Ano2 anoctamin 2 enables IDA
ISO
IBA
IMP
MGI:5052299 (PMID:19474308), (PMID:19475416), (PMID:19561302), (PMID:20056604), (PMID:21516098), (PMID:22075693), (PMID:23532839)
GO_REF:0000033
(PMID:19474308), (PMID:21984732)
RGD
GO_Central
PMID:19474308 PMID:19475416 PMID:19561302 PMID:20056604 PMID:21516098 More... GO_REF:0000033, RGD:9684847, RGD:9684847 NCBI chr 4:158,514,200...158,855,639
Ensembl chr 4:158,496,014...158,855,651
JBrowse link
G Ano3 anoctamin 3 NOT|enables ISO (PMID:21984732)
(PMID:23532839)
RGD PMID:21984732 PMID:23532839 NCBI chr 3:97,235,671...97,550,090
Ensembl chr 3:97,238,354...97,550,154
JBrowse link
G Ano4 anoctamin 4 enables
NOT|enables
ISO
IBA
(PMID:22946059)
(PMID:22075693), (PMID:23532839)
GO_REF:0000033
RGD
GO_Central
PMID:22075693 PMID:22946059 PMID:23532839 GO_REF:0000033 NCBI chr 7:23,329,015...23,738,423
Ensembl chr 7:23,329,070...23,738,434
JBrowse link
G Ano5 anoctamin 5 enables
NOT|enables
ISO (PMID:22946059)
(PMID:23532839)
(PMID:22075693)
RGD PMID:22075693 PMID:22946059 PMID:23532839 NCBI chr 1:101,086,490...101,187,547
Ensembl chr 1:101,087,341...101,187,555
JBrowse link
G Ano6 anoctamin 6 enables
NOT|enables
ISO (PMID:22946059)
(PMID:20056604), (PMID:23159814), (PMID:30785399)
(PMID:22075693), (PMID:23532839)
(PMID:21984732)
RGD PMID:20056604 PMID:21984732 PMID:22075693 PMID:22946059 PMID:23159814 More... NCBI chr 7:126,933,919...127,113,588
Ensembl chr 7:126,933,936...127,113,589
JBrowse link
G Ano7 anoctamin 7 enables
NOT|enables
ISO (PMID:22946059)
(PMID:23532839)
(PMID:21984732), (PMID:22075693)
RGD PMID:21984732 PMID:22075693 PMID:22946059 PMID:23532839 NCBI chr 9:93,917,524...93,945,323
Ensembl chr 9:93,917,524...93,945,323
JBrowse link
G Ano8 anoctamin 8 enables
NOT|enables
ISO (PMID:22946059)
(PMID:23532839)
(PMID:21984732), (PMID:22178883)
RGD PMID:21984732 PMID:22178883 PMID:22946059 PMID:23532839 NCBI chr16:18,163,853...18,173,248
Ensembl chr16:18,163,843...18,173,545
JBrowse link
G Ano9 anoctamin 9 enables
NOT|enables
ISO (PMID:22946059)
(PMID:23532839)
(PMID:21984732), (PMID:22178883)
RGD PMID:21984732 PMID:22178883 PMID:22946059 PMID:23532839 NCBI chr 1:196,208,863...196,230,381
Ensembl chr 1:196,197,341...196,229,900
JBrowse link
G Best1 bestrophin 1 enables ISO (PMID:11904445), (PMID:12907679), (PMID:18179881), (PMID:18400985), (PMID:19853238), (PMID:21330666), (PMID:26200502), (PMID:26720466), (PMID:35789156) RGD PMID:11904445 PMID:12907679 PMID:18179881 PMID:18400985 PMID:19853238 More... NCBI chr 1:206,629,340...206,646,085
Ensembl chr 1:206,629,500...206,646,063
JBrowse link
G Best3 bestrophin 3 enables ISO (PMID:12907679) RGD PMID:12907679 NCBI chr 7:52,586,824...52,656,776
Ensembl chr 7:52,615,776...52,656,766
JBrowse link
G Best4 bestrophin 4 enables ISO (PMID:12907679) RGD PMID:12907679 NCBI chr 5:130,622,194...130,629,045
Ensembl chr 5:130,623,438...130,627,099
JBrowse link
G Clca1 chloride channel accessory 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369
JBrowse link
G Clca2 chloride channel accessory 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:233,993,619...234,022,691
Ensembl chr 2:233,995,078...234,022,199
JBrowse link
G Clca4 chloride channel accessory 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:233,883,625...233,904,993
Ensembl chr 2:233,883,851...233,903,089
JBrowse link
G Clca4l chloride channel calcium activated 4-like enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:233,826,133...233,846,137
Ensembl chr 2:233,826,133...233,846,716
JBrowse link
G Clca5 chloride channel accessory 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:233,796,569...233,818,867
Ensembl chr 2:233,796,575...233,818,949
JBrowse link
G Clns1a chloride nucleotide-sensitive channel 1A enables ISO (PMID:15905169) RGD PMID:15905169 NCBI chr 1:152,019,369...152,039,670
Ensembl chr 1:152,019,378...152,039,661
JBrowse link
G Nmur2 neuromedin U receptor 2 enables ISO
IEA
(PMID:10899166)
GO_REF:0000107
RGD
Ensembl
PMID:10899166 GO_REF:0000107 NCBI chr10:40,166,223...40,182,078
Ensembl chr10:40,166,226...40,182,078
JBrowse link
G Ttyh1 tweety family member 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:70,053,312...70,071,872
Ensembl chr 1:70,053,324...70,071,845
JBrowse link
G Ttyh2 tweety family member 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:99,709,063...99,753,449
Ensembl chr10:99,709,007...99,753,444
JBrowse link
G Ttyh3 tweety family member 3 enables ISO
IBA
(PMID:16219661)
GO_REF:0000033
RGD
GO_Central
PMID:16219661 GO_REF:0000033 NCBI chr12:13,996,831...14,025,457
Ensembl chr12:13,997,045...14,025,459
JBrowse link
pH-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp6 aquaporin 6 enables IDA PMID:10647010 UniProt PMID:10647010 RGD:408345219 NCBI chr 7:130,732,216...130,735,149
Ensembl chr 7:130,633,579...130,735,194
Ensembl chr 7:130,633,579...130,735,194
JBrowse link
G Pacc1 proton activated chloride channel 1 enables ISS
ISO
IEA
GO_REF:0000024
(PMID:31023925)
GO_REF:0000107
(PMID:31023925), (PMID:31318332)
UniProt
RGD
Ensembl
PMID:31023925 PMID:31318332 GO_REF:0000024 GO_REF:0000107 NCBI chr13:102,904,668...102,929,770
Ensembl chr13:102,894,612...102,929,770
JBrowse link
voltage-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano1 anoctamin 1 enables ISO (PMID:22634729) RGD PMID:22634729 NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069
JBrowse link
G Ano6 anoctamin 6 enables ISO (PMID:22006324) RGD PMID:22006324 NCBI chr 7:126,933,919...127,113,588
Ensembl chr 7:126,933,936...127,113,589
JBrowse link
G Clcn1 chloride voltage-gated channel 1 enables IDA
IBA
ISO
IEA
GO_REF:0000033
(PMID:22521272), (PMID:26007199), (PMID:26502825)
GO_REF:0000104
GO_Central
RGD
UniProt
PMID:22521272 PMID:26007199 PMID:26502825 PMID:1659664 GO_REF:0000033 GO_REF:0000104, RGD:727583 NCBI chr 4:71,171,949...71,201,483
Ensembl chr 4:71,172,547...71,199,984
JBrowse link
G Clcn2 chloride voltage-gated channel 2 enables IDA
IMP
ISO
IBA
IEA
PMID:1334533
PMID:8816717
(PMID:16155254), (PMID:29403011), (PMID:36964785)
MGI:2183262 (PMID:11976342)
GO_REF:0000033
GO_REF:0000002
RGD
GO_Central
InterPro
PMID:11976342 PMID:16155254 PMID:29403011 PMID:36964785 PMID:1311421 More... GO_REF:0000002 GO_REF:0000033, RGD:69809, RGD:405650350, RGD:405650388 NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657
JBrowse link
G Clcn3 chloride voltage-gated channel 3 enables IDA
IBA
IEA
GO_REF:0000033
PMID:10915634
GO_REF:0000104
GO_Central
UniProt
RGD
PMID:10915634 PMID:10915634 GO_REF:0000033 GO_REF:0000104, RGD:628537, RGD:628537 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Clcn4 chloride voltage-gated channel 4 enables IEA
IBA
GO_REF:0000104
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000104 NCBI chr  X:23,729,194...23,795,391
Ensembl chr  X:23,729,338...23,793,238
JBrowse link
G Clcn5 chloride voltage-gated channel 5 enables IDA
IBA
IEA
ISO
GO_REF:0000033
GO_REF:0000104
(PMID:8559248)
GO_Central
UniProt
RGD
PMID:8559248 PMID:8626585 GO_REF:0000033 GO_REF:0000104, RGD:727659 NCBI chr  X:15,185,380...15,339,977
Ensembl chr  X:15,185,451...15,334,264
JBrowse link
G Clcn6 chloride voltage-gated channel 6 enables ISO (PMID:20466723) RGD PMID:20466723 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
JBrowse link
G Clcn7 chloride voltage-gated channel 7 enables IEA GO_REF:0000002
GO_REF:0000104
InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chr10:14,151,758...14,177,130
Ensembl chr10:14,151,758...14,177,130
JBrowse link
G Clcnka chloride voltage-gated channel Ka enables IEA
IBA
TAS
GO_REF:0000104
GO_REF:0000033
PMID:8041726
UniProt
GO_Central
PMID:8041726 GO_REF:0000033 GO_REF:0000104, RGD:632474 NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148
JBrowse link
G Clcnkb chloride voltage-gated channel Kb enables IEA
IBA
TAS
GO_REF:0000104
GO_REF:0000033
PMID:8041726
UniProt
GO_Central
PMID:8041726 GO_REF:0000033 GO_REF:0000104, RGD:632474 NCBI chr 5:153,710,086...153,733,162
Ensembl chr 5:153,710,094...153,732,153
JBrowse link
G Clic1 chloride intracellular channel 1 TAS RGD PMID:15190104 RGD:1304001 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
JBrowse link
G Tmc4 transmembrane channel-like 4 enables ISS
ISO
GO_REF:0000024
(PMID:34429071)
(PMID:34429071), (PMID:34468713)
UniProt
RGD
PMID:34429071 PMID:34468713 GO_REF:0000024 NCBI chr 1:65,539,777...65,551,683
Ensembl chr 1:65,539,721...65,551,677
JBrowse link
volume-sensitive chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 enables IMP PMID:1334533 UniProt PMID:1334533 RGD:405650350 NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657
JBrowse link
G Clcn3 chloride voltage-gated channel 3 enables
NOT|enables
ISO
IEA
(PMID:12183454)
GO_REF:0000107
MGI:2183297 (PMID:11182090)
RGD
Ensembl
PMID:11182090 PMID:12183454 GO_REF:0000107 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Ttyh1 tweety family member 1 enables ISO
ISS
IBA
(PMID:16219661)
GO_REF:0000024
(PMID:31138989)
GO_REF:0000033
RGD
UniProt
GO_Central
PMID:16219661 PMID:31138989 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:70,053,312...70,071,872
Ensembl chr 1:70,053,324...70,071,845
JBrowse link
G Ttyh2 tweety family member 2 enables ISO
IBA
(PMID:31138989)
GO_REF:0000033
RGD
GO_Central
PMID:31138989 GO_REF:0000033 NCBI chr10:99,709,063...99,753,449
Ensembl chr10:99,709,007...99,753,444
JBrowse link
G Ttyh3 tweety family member 3 enables ISO
IBA
(PMID:31138989)
GO_REF:0000033
RGD
GO_Central
PMID:31138989 GO_REF:0000033 NCBI chr12:13,996,831...14,025,457
Ensembl chr12:13,997,045...14,025,459
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20634
    transporter activity 1253
      transmembrane transporter activity 1153
        monoatomic ion transmembrane transporter activity 762
          monoatomic ion channel activity 451
            monoatomic anion channel activity 102
              chloride channel activity 81
                GABA-gated chloride ion channel activity 18
                extracellularly glutamate-gated chloride channel activity 2
                extracellularly glycine-gated chloride channel activity 5
                glycine-gated chloride ion channel activity 2
                histamine-gated chloride channel activity 0
                intracellularly ATP-gated chloride channel activity 1
                intracellularly calcium-gated chloride channel activity 23
                pH-gated chloride channel activity 2
                serotonin-gated chloride channel activity 0
                voltage-gated chloride channel activity + 13
                volume-sensitive chloride channel activity 5
Path 2
Term Annotations click to browse term
  molecular_function 20634
    transporter activity 1253
      transmembrane transporter activity 1153
        passive transmembrane transporter activity 511
          channel activity 511
            monoatomic ion channel activity 451
              monoatomic anion channel activity 102
                chloride channel activity 81
                  GABA-gated chloride ion channel activity 18
                  extracellularly glutamate-gated chloride channel activity 2
                  extracellularly glycine-gated chloride channel activity 5
                  glycine-gated chloride ion channel activity 2
                  histamine-gated chloride channel activity 0
                  intracellularly ATP-gated chloride channel activity 1
                  intracellularly calcium-gated chloride channel activity 23
                  pH-gated chloride channel activity 2
                  serotonin-gated chloride channel activity 0
                  voltage-gated chloride channel activity + 13
                  volume-sensitive chloride channel activity 5
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