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ONTOLOGY REPORT - ANNOTATIONS

Term:GABA-gated chloride ion channel activity
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Accession:GO:0022851 term browser browse the term
Definition:Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts.


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GABA-gated chloride ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 contributes_to
enables		 ISS
ISO
IEA
IDA
IBA		 GO_REF:0000024
(PMID:23909897)
GO_REF:0000107
(PMID:2538761), (PMID:30602789), (PMID:9039914)
PMID:9882711
(PMID:27129275)
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:2538761 PMID:9039914 PMID:23909897 PMID:27129275 PMID:30602789 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:405650244 NCBI chr10:27,096,731...27,152,563
Ensembl chr10:26,595,160...26,650,864 		JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 enables ISO
IBA		 (PMID:9039914)
GO_REF:0000033		 RGD
GO_Central		 PMID:9039914 GO_REF:0000033 NCBI chr14:37,451,218...37,587,458
Ensembl chr14:37,097,279...37,228,944 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 enables ISS
IEA
ISO
IDA
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:16412217), (PMID:29053855)
PMID:9882711
GO_REF:0000033		 UniProt
Ensembl
RGD
GO_Central		 PMID:16412217 PMID:29053855 PMID:9882711 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:405650244 NCBI chr  X:155,301,979...155,543,870
Ensembl chr  X:150,261,607...150,501,559 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:36,944,747...37,021,652
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 enables ISS
IDA
ISO
IBA
IEA		 GO_REF:0000024
PMID:10462548
(PMID:14993607)
GO_REF:0000033
GO_REF:0000107		 UniProt
RGD
GO_Central
Ensembl		 PMID:14993607 PMID:10462548 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:405650343 NCBI chr 1:117,404,446...117,517,424
Ensembl chr 1:108,268,776...108,380,917 		JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 contributes_to IMP RGD PMID:17395622 RGD:1626515 NCBI chr10:27,311,965...27,327,337
Ensembl chr10:26,810,423...26,825,769 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:16412217), (PMID:2538761), (PMID:26950270), (PMID:9039914)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:2538761 PMID:9039914 PMID:16412217 PMID:26950270 GO_REF:0000024 GO_REF:0000107 NCBI chr14:36,434,339...36,917,920
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 contributes_to ISS
ISO
IEA		 GO_REF:0000024
(PMID:23909897)
(PMID:27129275)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:23909897 PMID:27129275 GO_REF:0000024 GO_REF:0000107 NCBI chr10:27,438,127...27,657,680
Ensembl chr10:26,936,551...27,151,251 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 contributes_to
enables		 ISS
ISO
IDA		 GO_REF:0000024
(PMID:22303015), (PMID:26950270), (PMID:30602789), (PMID:9039914)
PMID:10462548
(PMID:9108119)
(PMID:27129275)		 UniProt
RGD		 PMID:9039914 PMID:9108119 PMID:22303015 PMID:26950270 PMID:27129275 More... GO_REF:0000024, RGD:405650343 NCBI chr 1:117,602,772...117,838,230
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gabre gamma-aminobutyric acid type A receptor subunit epsilon enables ISO
ISS
IBA		 (PMID:16412217), (PMID:9039914), (PMID:9882711)
GO_REF:0000024
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:9039914 PMID:9882711 PMID:16412217 GO_REF:0000024 GO_REF:0000033 NCBI chr  X:155,102,078...155,120,821
Ensembl chr  X:150,060,040...150,078,693 		JBrowse link
G Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:37,750,292...37,821,651
Ensembl chr14:37,396,294...37,635,956 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 contributes_to
enables		 ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:23909897)
(PMID:2538761), (PMID:30602789)
(PMID:27129275)
GO_REF:0000033
GO_REF:0000107		 UniProt
RGD
GO_Central
Ensembl		 PMID:2538761 PMID:23909897 PMID:27129275 PMID:30602789 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 enables IDA
IBA		 PMID:10462548
GO_REF:0000033		 GO_Central PMID:10462548 GO_REF:0000033, RGD:405650343 NCBI chr 1:116,763,332...117,386,770
Ensembl chr 1:107,627,390...108,246,763 		JBrowse link
G Gabrp gamma-aminobutyric acid type A receptor subunit pi enables ISO
ISS
IMP
IEA		 (PMID:10462548)
GO_REF:0000024
PMID:17003036
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:10462548 PMID:17003036 GO_REF:0000024 GO_REF:0000107, RGD:405650305 NCBI chr10:18,143,031...18,169,595
Ensembl chr10:18,143,038...18,169,516 		JBrowse link
G Gabrq gamma-aminobutyric acid type A receptor subunit theta enables ISO
IEA		 (PMID:16412217)
GO_REF:0000107		 RGD
Ensembl		 PMID:16412217 GO_REF:0000107 NCBI chr  X:155,737,838...155,755,225
Ensembl chr  X:150,696,427...150,709,919 		JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 enables IDA PMID:8524843 UniProt PMID:8524843 RGD:728796 NCBI chr 5:52,320,475...52,357,549
Ensembl chr 5:47,524,151...47,561,228 		JBrowse link
G Gabrr2 gamma-aminobutyric acid type A receptor subunit rho 2 enables IDA PMID:8524843 UniProt PMID:8524843 RGD:728796 NCBI chr 5:52,242,564...52,286,255
Ensembl chr 5:47,452,150...47,489,809 		JBrowse link
G Gabrr3 gamma-aminobutyric acid type A receptor subunit rho3 enables IDA PMID:11861315 UniProt PMID:11861315 RGD:405650323 NCBI chr11:54,372,017...54,424,466
Ensembl chr11:40,902,812...40,955,263 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21100
    molecular transducer activity 2665
      signaling receptor activity 2665
        neurotransmitter receptor activity 96
          transmitter-gated channel activity 60
            transmitter-gated monoatomic ion channel activity 60
              GABA-gated chloride ion channel activity 18
Path 2
Term Annotations click to browse term
  molecular_function 21100
    transporter activity 1274
      transmembrane transporter activity 1165
        passive transmembrane transporter activity 516
          channel activity 516
            gated channel activity 335
              ligand-gated channel activity 190
                ligand-gated monoatomic ion channel activity 185
                  extracellular ligand-gated monoatomic ion channel activity 70
                    transmitter-gated monoatomic ion channel activity 60
                      GABA-gated chloride ion channel activity 18
paths to the root