Pacc1 (proton activated chloride channel 1) - Rat Genome Database

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Gene: Pacc1 (proton activated chloride channel 1) Rattus norvegicus
Analyze
Symbol: Pacc1
Name: proton activated chloride channel 1
RGD ID: 1359339
Description: Predicted to enable pH-gated chloride channel activity. Predicted to be involved in chloride transport. Predicted to act upstream of or within chloride transmembrane transport. Predicted to be integral component of plasma membrane. Predicted to be part of chloride channel complex. Orthologous to human PACC1 (proton activated chloride channel 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC95217; PAC; proton-activated chloride channel; RGD1359339; similar to RIKEN cDNA 2310028N02; Tmem206; transmembrane protein 206
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.213102,904,668 - 102,929,770 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl13102,894,612 - 102,929,770 (+)Ensembl
Rnor_6.013110,006,975 - 110,032,790 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,007,010 - 110,031,895 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013114,572,868 - 114,597,637 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413107,387,221 - 107,412,108 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113107,576,324 - 107,601,210 (+)NCBI
Celera13102,343,772 - 102,368,659 (+)NCBICelera
Cytogenetic Map13q27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:19581412   PMID:31023925   PMID:31318332  


Genomics

Comparative Map Data
Pacc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.213102,904,668 - 102,929,770 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl13102,894,612 - 102,929,770 (+)Ensembl
Rnor_6.013110,006,975 - 110,032,790 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,007,010 - 110,031,895 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013114,572,868 - 114,597,637 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413107,387,221 - 107,412,108 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113107,576,324 - 107,601,210 (+)NCBI
Celera13102,343,772 - 102,368,659 (+)NCBICelera
Cytogenetic Map13q27NCBI
PACC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381212,363,928 - 212,414,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1212,363,928 - 212,414,901 (-)EnsemblGRCh38hg38GRCh38
GRCh371212,537,270 - 212,588,228 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,604,439 - 210,654,890 (-)NCBINCBI36hg18NCBI36
Celera1185,763,548 - 185,813,983 (-)NCBI
Cytogenetic Map1q32.3NCBI
HuRef1183,214,097 - 183,264,414 (-)NCBIHuRef
CHM1_11213,810,681 - 213,861,148 (-)NCBICHM1_1
T2T-CHM13v2.01211,608,613 - 211,659,583 (-)NCBI
Pacc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391191,058,099 - 191,083,481 (+)NCBIGRCm39mm39
GRCm39 Ensembl1191,058,109 - 191,083,111 (+)Ensembl
GRCm381191,325,902 - 191,351,284 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,325,912 - 191,350,914 (+)EnsemblGRCm38mm10GRCm38
MGSCv371193,149,844 - 193,176,804 (+)NCBIGRCm37mm9NCBIm37
MGSCv361193,026,580 - 193,053,540 (+)NCBImm8
Celera1198,256,067 - 198,283,053 (+)NCBICelera
Cytogenetic Map1H6NCBI
Pacc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554065,035,745 - 5,058,189 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554065,036,167 - 5,058,189 (+)NCBIChiLan1.0ChiLan1.0
PACC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11192,790,932 - 192,843,577 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1192,790,932 - 192,843,577 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01187,928,923 - 187,980,274 (-)NCBIMhudiblu_PPA_v0panPan3
PACC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1710,568,030 - 10,606,672 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl710,568,026 - 10,610,578 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha710,143,342 - 10,181,979 (-)NCBI
ROS_Cfam_1.0710,273,755 - 10,312,411 (-)NCBI
ROS_Cfam_1.0 Ensembl710,273,755 - 10,312,420 (-)Ensembl
UMICH_Zoey_3.1710,196,568 - 10,235,194 (-)NCBI
UNSW_CanFamBas_1.0710,297,886 - 10,336,505 (-)NCBI
UU_Cfam_GSD_1.0710,421,365 - 10,460,215 (-)NCBI
Pacc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934463,868,253 - 63,901,887 (+)NCBI
SpeTri2.0NW_0049365571,108,556 - 1,142,844 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PACC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9130,835,317 - 131,001,479 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19130,968,208 - 131,001,491 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29144,015,830 - 144,048,093 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PACC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12517,116,762 - 17,160,851 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2517,116,852 - 17,161,760 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605517,617,246 - 17,661,350 (+)NCBIVero_WHO_p1.0
Pacc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477117,863,411 - 17,900,353 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462477117,863,411 - 17,900,222 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH78888  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.213102,919,124 - 102,919,277 (+)MAPPERmRatBN7.2
Rnor_6.013110,021,411 - 110,021,563NCBIRnor6.0
Rnor_5.013114,586,992 - 114,587,144UniSTSRnor5.0
RGSC_v3.413107,401,622 - 107,401,774UniSTSRGSC3.4
Celera13102,358,173 - 102,358,325UniSTS
Cytogenetic Map13q27UniSTS
RH134564  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.213102,929,368 - 102,929,550 (+)MAPPERmRatBN7.2
Rnor_6.013110,031,655 - 110,031,836NCBIRnor6.0
Rnor_5.013114,597,236 - 114,597,417UniSTSRnor5.0
RGSC_v3.413107,411,866 - 107,412,047UniSTSRGSC3.4
Celera13102,368,417 - 102,368,598UniSTS
RH 3.4 Map13727.8UniSTS
Cytogenetic Map13q27UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:232
Count of miRNA genes:154
Interacting mature miRNAs:168
Transcripts:ENSRNOT00000005387
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 34 17 10 18 10 74 35 41 10
Low 1 9 39 30 1 30 8 11 1 8
Below cutoff 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000005387   ⟹   ENSRNOP00000005387
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl13102,904,682 - 102,929,769 (+)Ensembl
Rnor_6.0 Ensembl13110,007,010 - 110,031,895 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105057   ⟹   ENSRNOP00000078608
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl13102,906,701 - 102,929,770 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114123   ⟹   ENSRNOP00000085237
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl13102,894,612 - 102,929,770 (+)Ensembl
RefSeq Acc Id: NM_001007679   ⟹   NP_001007680
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.213102,904,724 - 102,929,611 (+)NCBI
Rnor_6.013110,007,010 - 110,031,897 (+)NCBI
Rnor_5.013114,572,868 - 114,597,637 (+)NCBI
RGSC_v3.413107,387,221 - 107,412,108 (+)RGD
Celera13102,343,772 - 102,368,659 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250481   ⟹   XP_006250543
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.213102,904,668 - 102,929,770 (+)NCBI
Rnor_6.013110,006,980 - 110,032,790 (+)NCBI
Rnor_5.013114,572,868 - 114,597,637 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008769855   ⟹   XP_008768077
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.213102,904,668 - 102,929,770 (+)NCBI
Rnor_6.013110,006,975 - 110,032,056 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001007680 (Get FASTA)   NCBI Sequence Viewer  
  XP_006250543 (Get FASTA)   NCBI Sequence Viewer  
  XP_008768077 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH82061 (Get FASTA)   NCBI Sequence Viewer  
  EDL95002 (Get FASTA)   NCBI Sequence Viewer  
  Q66H28 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001007680   ⟸   NM_001007679
- UniProtKB: Q66H28 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006250543   ⟸   XM_006250481
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008768077   ⟸   XM_008769855
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000005387   ⟸   ENSRNOT00000005387
RefSeq Acc Id: ENSRNOP00000085237   ⟸   ENSRNOT00000114123
RefSeq Acc Id: ENSRNOP00000078608   ⟸   ENSRNOT00000105057

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66H28-F1-model_v2 AlphaFold Q66H28 1-350 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699115
Promoter ID:EPDNEW_R9640
Type:initiation region
Name:Tmem206_1
Description:transmembrane protein 206
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013110,006,968 - 110,007,028EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 110030397 110030398 A C snv BXH2/CubMcwi (2020)


Assembly: mRatBN7.2
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
13 102928111 102928112 A C snv BXH2/CubMcwi (2020)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359339 AgrOrtholog
BioCyc Gene G2FUF-16846 BioCyc
Ensembl Genes ENSRNOG00000003915 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000005387 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000078608.1 UniProtKB/TrEMBL
  ENSRNOP00000085237.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005387 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000105057.1 UniProtKB/TrEMBL
  ENSRNOT00000114123.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7132483 IMAGE-MGC_LOAD
InterPro TMEM206 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:305070 UniProtKB/Swiss-Prot
MGC_CLONE MGC:95217 IMAGE-MGC_LOAD
NCBI Gene 305070 ENTREZGENE
PANTHER PTHR16087 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TMEM206 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pacc1 PhenoGen
UniProt A0A8I5ZNJ7_RAT UniProtKB/TrEMBL
  A0A8I6A2U8_RAT UniProtKB/TrEMBL
  Q66H28 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-05 Pacc1  proton activated chloride channel 1  Tmem206  transmembrane protein 206  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-02 Tmem206  transmembrane protein 206  RGD1359339  similar to RIKEN cDNA 2310028N02  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 RGD1359339  similar to RIKEN cDNA 2310028N02  MGC95217    Symbol updated 1299863 APPROVED
2005-07-29 MGC95217  similar to RIKEN cDNA 2310028N02      Symbol and Name status set to provisional 70820 PROVISIONAL