| 2624 | Fn1 | fibronectin 1 | ENCODES a protein that exhibits mercury ion binding; protease binding; identical protein binding (ortholog); INVOLVED IN cell-matrix adhesion; cellular response to amyloid-beta; cellular response to angiotensin; PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; ASSOCIATED WITH acute kidney failure; Binge Drinking; calcium oxalate nephrolithiasis; FOUND IN basement membrane; extracellular space; apical plasma membrane (ortholog); INTERACTS WITH (R)-lipoic acid; 1-(5-isoquinolinesulfonyl)-2-methylpiperazine; 17alpha-ethynylestradiol | 9 | 80645507 | 80714200 | Rat | 1018 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1559983 | Fn3k | fructosamine 3 kinase | ENCODES a protein that exhibits protein-fructosamine 3-kinase activity (ortholog); INVOLVED IN epithelial cell differentiation (ortholog); fructosamine metabolic process (ortholog); peptidyl-lysine deglycation (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schi sandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 10 | 107198566 | 107214176 | Rat | 127 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 2625 | Fnta | farnesyltransferase, CAAX box, subunit alpha | ENCODES a protein that exhibits CAAX-protein geranylgeranyltransferase activity; heterocyclic compound binding; peptide binding; INVOLVED IN negative regulation of apoptotic process; positive regulation of cell cycle; positive regulation of cell population proliferation; FOUND IN CAAX-protein gerany lgeranyltransferase complex; microtubule associated complex (ortholog); protein farnesyltransferase complex (ortholog); INTERACTS WITH (+)-schisandrin B; (S)-(-)-perillyl alcohol; 2,4-dinitrotoluene | 16 | 72767864 | 72786193 | Rat | 173 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620119 | Fntb | farnesyltransferase, CAAX box, subunit beta | ENCODES a protein that exhibits peptide binding; protein farnesyltransferase activity; acetyltransferase activator activity (ortholog); INVOLVED IN positive regulation of cell cycle; positive regulation of cell population proliferation; CAAX-box protein maturation (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN microtubule associated complex (ortholog); protein farnesyltransferase complex (ortholog); INTERACTS WITH (S)-(-)-perillyl alcohol; 1,2,4-trimethylbenzene; 17beta-estradiol | 6 | 101269657 | 101352716 | Rat | 135 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621350 | Fnbp1 | formin binding protein 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN nervous system development; FOUND IN plasma membrane (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 3-chloropropane-1,2-diol; 4-amino-2,6-dinitrotoluene | 3 | 34706814 | 34826770 | Rat | 142 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1309238 | Fnbp4 | formin binding protein 4 | FOUND IN nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 97188852 | 97218916 | Rat | 104 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1310640 | Fndc1 | fibronectin type III domain containing 1 | INVOLVED IN cellular response to hypoxia; positive regulation of cardiac muscle cell apoptotic process; positive regulation of protein phosphorylation; FOUND IN cell-cell junction; cytoplasm; mitochondrial membrane; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodib enzodioxine | 1 | 49686856 | 49769263 | Rat | 100 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 6496095 | Fndc4 | fibronectin type III domain containing 4 | INVOLVED IN negative regulation of inflammatory response (ortholog); response to transforming growth factor beta (ortholog); ASSOCIATED WITH lipid storage disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta- estradiol; bisphenol A; (1->4)-beta-D-glucan (ortholog) | 6 | 30797102 | 30800782 | Rat | 91 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 708525 | Fndc5 | fibronectin type III domain containing 5 | ENCODES a protein that exhibits hormone activity (inferred); INVOLVED IN positive regulation of brown fat cell differentiation (ortholog); response to muscle activity (ortholog); ASSOCIATED WITH Cardiomegaly (ortholog); endomyocardial fibrosis (ortholog); hypertension (ortholog); FOUND IN endoplasmi c reticulum (ortholog); extracellular region (ortholog); plasma membrane (ortholog); INTERACTS WITH (R)-noradrenaline; 17beta-estradiol; 17beta-estradiol 3-benzoate | 5 | 146765951 | 146775611 | Rat | 147 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1309189 | Fndc7 | fibronectin type III domain containing 7 | INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A | 2 | 199189029 | 199226425 | Rat | 30 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310708 | Fndc8 | fibronectin type III domain containing 8 | ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); INTERACTS WITH bisphenol A; C60 fullerene; furan | 10 | 68323500 | 68331638 | Rat | 20 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2318580 | Fndc9 | fibronectin type III domain containing 9 | INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; testosterone | 10 | 31166051 | 31170964 | Rat | 18 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 2318339 | Fnip1 | folliculin interacting protein 1 | ENCODES a protein that exhibits ATPase inhibitor activity (ortholog); enzyme activator activity (ortholog); enzyme binding (ortholog); INVOLVED IN B cell differentiation (ortholog); cellular response to starvation (ortholog); immature B cell differentiation (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH genetic disease (ortholog); immunodeficiency 93 (ortholog); Wolff-Parkinson-White syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 17beta-estradiol; acetamide; amitrole | 10 | 39068432 | 39151552 | Rat | 138 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1562174 | Fnip2 | folliculin interacting protein 2 | ENCODES a protein that exhibits ATPase inhibitor activity (ortholog); protein-folding chaperone binding (ortholog); INVOLVED IN intrinsic apoptotic signaling pathway in response to DNA damage (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of transcri ption by RNA polymerase II (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Leukoencephalopathies (ortholog); FOUND IN centriolar satellite (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,4,7,8-Pentachlorodibenzofuran | 2 | 166894726 | 167006490 | Rat | 118 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1304570 | Fn3krp | fructosamine-3-kinase-related protein | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); protein-ribulosamine 3-kinase activity (inferred); INVOLVED IN DNA-templated transcription (inferred); positive regulation of DNA-templated transcription (inferred); regulation of DNA-templa ted transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH (+)-schisandrin B; 2,2',5,5'-tetrachlorobiphenyl; bisphenol A | 10 | 107186695 | 107195419 | Rat | 74 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1305386 | Fnbp1l | formin binding protein 1-like | ENCODES a protein that exhibits GTPase binding (ortholog); INVOLVED IN cilium assembly (ortholog); clathrin-dependent endocytosis (ortholog); membrane invagination (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ort holog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | 2 | 213331871 | 213432821 | Rat | 150 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1589420 | Fndc10 | fibronectin type III domain containing 10 | FOUND IN membrane (inferred); INTERACTS WITH 17beta-estradiol; bisphenol A; ochratoxin A | 5 | 171581960 | 171584519 | Rat | 36 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1564340 | Fndc11 | fibronectin type III domain containing 11 | ASSOCIATED WITH neuronal ceroid lipofuscinosis (ortholog); INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); acrylamide (ortholog) | 3 | 188708045 | 188710670 | Rat | 34 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304736 | Fndc3a | fibronectin type III domain containing 3a | INVOLVED IN cell-cell adhesion (ortholog); fertilization (ortholog); Sertoli cell development (ortholog); FOUND IN acrosomal vesicle (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; acetamide | 15 | 54099510 | 54276963 | Rat | 99 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1311673 | Fndc3b | fibronectin type III domain containing 3B | INVOLVED IN cell migration (ortholog); negative regulation of osteoblast differentiation (ortholog); positive regulation of fat cell differentiation (ortholog); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); Drug-Related Side Effects and Adverse Reactions (ortholog); keratoconus (ortholog) ; FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 2 | 112240108 | 112546113 | Rat | 151 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563846 | Fndc3c1 | fibronectin type III domain containing 3C1 | INTERACTS WITH 17beta-estradiol; 2,3,7,8-Tetrachlorodibenzofuran; 2-methoxyethanol | X | 75562242 | 75630812 | Rat | 11 | symbol , PhenoGen | gene, protein-coding, INFERRED [RefSeq] |
| 62039 | Plk3 | polo-like kinase 3 | ENCODES a protein that exhibits p53 binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cytoplasmic microtubule organization (ortholog); DNA damage response (ortholog); G1/S transition of mitotic cell cycle (ortholog); PARTICIPATES IN tuberculosis pathway; ASSOCIATED WITH breast carcinoma (ortholog); COVID-19 (ortholog); ovary epithelial cancer (ortholog); FOUND IN dendrite; neuronal cell body; centrosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene | 5 | 135843725 | 135848900 | Rat | 307 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 631329 | Tnfrsf12a | TNF receptor superfamily member 12A | INVOLVED IN positive regulation of collagen biosynthetic process; cell adhesion (ortholog); extrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; ASSOCIATED WITH Pulmonary Arterial Hypertension; acute kidney failure (ortholog); Experimental Liver Cirr hosis (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog); ruffle (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate | 10 | 13211670 | 13213666 | Rat | 312 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311401 | Prpf40a | pre-mRNA processing factor 40A | ENCODES a protein that exhibits proline-rich region binding (ortholog); INVOLVED IN mRNA cis splicing, via spliceosome (inferred); mRNA processing (inferred); RNA splicing (inferred); PARTICIPATES IN spliceosome pathway; FOUND IN nuclear matrix (ortholog); nuclear speck (ortholog); nucleus (ortholog ); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 3 | 58036779 | 58098996 | Rat | 106 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311878 | Actr8 | actin related protein 8 | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN Ino80 complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride | 16 | 5170649 | 5192883 | Rat | 64 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1560041 | Agfg1 | ArfGAP with FG repeats 1 | ENCODES a protein that exhibits DNA binding (inferred); GTPase activator activity (inferred); metal ion binding (inferred); INVOLVED IN acrosome assembly (ortholog); intermediate filament organization (ortholog); spermatid nucleus differentiation (ortholog); PARTICIPATES IN influenza A pathway; ASSO CIATED WITH Experimental Liver Cirrhosis (ortholog); oligoasthenoteratozoospermia (ortholog); FOUND IN cell projection (ortholog); cytoplasmic vesicle (ortholog); neuronal cell body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; 4,4'-diaminodiphenylmethane | 9 | 91572962 | 91630688 | Rat | 110 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1564895 | Ahcyl2 | adenosylhomocysteinase-like 2 | INVOLVED IN one-carbon metabolic process (inferred); PARTICIPATES IN cysteine and methionine metabolic pathway; ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN cytosol (ortholog); neuron projection (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-t hiouracil | 4 | 59348747 | 59498503 | Rat | 94 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 620052 | Atp5mc3 | ATP synthase membrane subunit c locus 3 | ENCODES a protein that exhibits ligand-gated channel activity; INVOLVED IN pore complex assembly; response to (R)-carnitine; response to ethanol; PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; ASSOCIATED WITH COVID-19 (ortholog); early-o nset dystonia and/or spastic paraplegia (ortholog); genetic disease (ortholog); FOUND IN cation channel complex; mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 3 | 79218014 | 79220664 | Rat | 117 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 619791 | Bub1b | BUB1 mitotic checkpoint serine/threonine kinase B | ENCODES a protein that exhibits ATP binding (inferred); protein kinase activity (inferred); INVOLVED IN metaphase/anaphase transition of mitotic cell cycle (ortholog); mitotic spindle assembly checkpoint signaling (ortholog); protein localization to chromosome, centromeric region (ortholog); PARTICI PATES IN cell cycle pathway, mitotic; mitotic spindle checkpoint pathway; ASSOCIATED WITH Aneuploidy (ortholog); cerebral palsy (ortholog); colon carcinoma (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); kinetochore (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 3 | 126017019 | 126069470 | Rat | 285 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 2291 | Ccnb1 | cyclin B1 | ENCODES a protein that exhibits protein kinase binding; protein-containing complex binding; cyclin-dependent protein serine/threonine kinase activator activity (ortholog); INVOLVED IN cellular response to fatty acid; cellular response to hypoxia; cellular response to iron(III) ion; PARTICIPATES IN c ell cycle pathway, mitotic; G1/S transition pathway; G2/M checkpoint pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; Experimental Liver Neoplasms; Experimental Seizures; FOUND IN centrosome (ortholog); cyclin B1-CDK1 complex (ortholog); cytoplasm (ortholog); INTERACTS WITH (-)-citrinin; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,3-dichloropropan-2-ol | 2 | 33646252 | 33655225 | Rat | 859 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 2315 | Cd81 | Cd81 molecule | ENCODES a protein that exhibits cholesterol binding (ortholog); integrin binding (ortholog); MHC class II protein binding (ortholog); INVOLVED IN regulation of cell population proliferation; regulation of growth; CD4-positive, alpha-beta T cell costimulation (ortholog); PARTICIPATES IN B cell recept or signaling pathway; hepatitis C pathway; malaria pathway; ASSOCIATED WITH common variable immunodeficiency (ortholog); common variable immunodeficiency 6 (ortholog); hepatitis C (ortholog); FOUND IN apical plasma membrane; basal plasma membrane (ortholog); basolateral plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-di-tert-butyl-4-methylphenol | 1 | 207665274 | 207681094 | Rat | 237 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1566215 | Copg2 | coat protein complex I subunit gamma 2 | ENCODES a protein that exhibits structural molecule activity (inferred); INVOLVED IN intra-Golgi vesicle-mediated transport (ortholog); ASSOCIATED WITH Weight Gain (ortholog); FOUND IN COPI vesicle coat (ortholog); COPI-coated vesicle (ortholog); Golgi membrane (ortholog); INTERACTS WITH 17beta-estr adiol; benzo[a]pyrene; bisphenol A | 4 | 60333455 | 60468953 | Rat | 95 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1565584 | Crebzf | CREB/ATF bZIP transcription factor | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of gene expression, epigenetic (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleus (orth olog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 1 | 153829544 | 153836073 | Rat | 98 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 2447 | Ctsh | cathepsin H | ENCODES a protein that exhibits aminopeptidase activity; identical protein binding; kininogen binding; INVOLVED IN cellular response to thyroid hormone stimulus; metanephros development; response to odorant; ASSOCIATED WITH Contusions; polycystic kidney disease; Sleep Deprivation; FOUND IN acrosomal vesicle; alveolar lamellar body; axoneme; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol | 8 | 99488756 | 99507639 | Rat | 321 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1306597 | Cyc1 | cytochrome c-1 | ENCODES a protein that exhibits electron transfer activity (inferred); heme binding (inferred); metal ion binding (inferred); INVOLVED IN response to glucagon; PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; ASSOCIATED WITH mitochondrial complex III deficiency nuclear type 1 (ortholog); mitochondrial complex III deficiency nuclear type 6 (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex III (ortholog); INTERACTS WITH 17beta-estradiol; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 109947750 | 109950142 | Rat | 145 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 621889 | Ddb1 | damage-specific DNA binding protein 1 | ENCODES a protein that exhibits damaged DNA binding; cullin family protein binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN biological process involved in interaction with symbiont (ortholog); cellular response to UV (ortholog); DNA damage response (ortholog); PARTICIPA TES IN altered nucleotide excision repair pathway; nucleotide excision repair pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); communication disorder (ortholog); congenital heart disease (ortholog); FOUND IN Cul4-RING E3 ubiquitin ligase complex (ortholog); Cul4A-RING E3 ubiquitin ligase complex (ortholog); Cul4B-RING E3 ubiquitin ligase complex (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 1 | 216677810 | 216703605 | Rat | 178 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1306989 | Dhrs7c | dehydrogenase/reductase 7C | ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (ortholog); INVOLVED IN D-glucose import (ortholog); D-glucose import across plasma membrane (ortholog); intracellular calcium ion homeostasis (ortholog); FOUND IN longitudinal sarcoplasmic reticulum (ortholog); sarcopla smic reticulum membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; aconitine | 10 | 52994205 | 53012281 | Rat | 58 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1306643 | Fam120a | family with sequence similarity 120 member A | FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acetamide | 17 | 15890151 | 15981337 | Rat | 80 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1303096 | Fut8 | fucosyltransferase 8 | ENCODES a protein that exhibits alpha-(1->6)-fucosyltransferase activity (ortholog); glycoprotein 6-alpha-L-fucosyltransferase activity (ortholog); glycosyltransferase activity (ortholog); INVOLVED IN cell migration (ortholog); GDP-L-fucose metabolic process (ortholog); integrin-mediated signaling p athway (ortholog); PARTICIPATES IN keratan sulfate biosynthetic pathway; N-linked glycan biosynthetic pathway; ASSOCIATED WITH Congenital Disorder of Glycosylation with Defective Fucosylation 1 (ortholog); genetic disease (ortholog); pulmonary emphysema (ortholog); FOUND IN Golgi cisterna membrane (inferred); membrane (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 6 | 101682354 | 101909784 | Rat | 168 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 620282 | Golga2 | golgin A2 | ENCODES a protein that exhibits importin-alpha family protein binding; protein kinase binding; protein-containing complex binding; INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport; Golgi disassembly; mitotic spindle assembly; ASSOCIATED WITH Developmental Delay with Hypotonia, M yopathy, and Brain Abnormalities (ortholog); neuromuscular disease (ortholog); FOUND IN cis-Golgi network; Golgi apparatus; Golgi cis cisterna; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 3 | 35981783 | 36002023 | Rat | 162 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 2721 | Got1 | glutamic-oxaloacetic transaminase 1 | ENCODES a protein that exhibits carboxylic acid binding; L-aspartate:2-oxoglutarate aminotransferase activity; L-cysteine transaminase activity; INVOLVED IN aspartate metabolic process; cellular response to mechanical stimulus; dicarboxylic acid metabolic process; PARTICIPATES IN gluconeogenesis pat hway; AGAT deficiency pathway; alkaptonuria pathway; ASSOCIATED WITH Acute Lung Injury; cardiomyopathy; Febrile Seizures; FOUND IN axon terminus; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH (+)-taxifolin; (2E,4E)-hexa-2,4-dienoic acid; (E)-thiamethoxam | 1 | 252306541 | 252337622 | Rat | 616 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 2787 | Hcrtr1 | hypocretin receptor 1 | ENCODES a protein that exhibits orexin receptor activity; peptide hormone binding; INVOLVED IN feeding behavior; G protein-coupled receptor signaling pathway; neuropeptide signaling pathway; PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1; orexin/hypocretin signaling pathway; ASSOCIATED WITH Cocaine-Related Disorders (ortholog); withdrawal disorder (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride | 5 | 147761392 | 147771846 | Rat | 103 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 2837 | Hsd17b7 | hydroxysteroid (17-beta) dehydrogenase 7 | ENCODES a protein that exhibits estradiol 17-beta-dehydrogenase [NAD(P)+] activity; prolactin receptor binding; 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity (ortholog); INVOLVED IN estrogen biosynthetic process; hippocampus development; maternal process involved in female pregnancy; PARTIC IPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH polycystic ovary syndrome; FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1-naphthyl isothiocyanate; 17beta-estradiol | 13 | 84702875 | 84722810 | Rat | 292 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1563216 | Isca2 | iron-sulfur cluster assembly 2 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN protein maturation (ortholog); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; ASSOCIATED WITH Developmental Disabilities (ortholog); genetic disease (ortholog); multiple mitochondrial dys functions syndrome (ortholog); FOUND IN mitochondrial [4Fe-4S] assembly complex (ortholog); mitochondrion (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,6-dinitrotoluene; 6-propyl-2-thiouracil | 6 | 110149593 | 110151103 | Rat | 71 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1563945 | Jade3 | jade family PHD finger 3 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN regulation of cell cycle (ortholog); regulation of DNA biosynthetic process (ortholog); regulation of DNA replication (ortholog); FOUND IN histone acetyltransferase complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; Cuprizon | X | 4222369 | 4424164 | Rat | 63 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 620239 | Kif2c | kinesin family member 2C | ENCODES a protein that exhibits microtubule plus-end binding (ortholog); INVOLVED IN attachment of mitotic spindle microtubules to kinetochore (ortholog); establishment or maintenance of microtubule cytoskeleton polarity (ortholog); metaphase chromosome alignment (ortholog); ASSOCIATED WITH colorect al cancer (ortholog); contact dermatitis (ortholog); COVID-19 (ortholog); FOUND IN chromosome, centromeric region (ortholog); cytoplasmic microtubule (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 5 | 135873925 | 135899267 | Rat | 253 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 62389 | Klf6 | KLF transcription factor 6 | ENCODES a protein that exhibits DNA-binding transcription factor activity; double-stranded DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to endothelin; cellular response to hydrogen peroxide; positive regulation of tra nscription by RNA polymerase II; ASSOCIATED WITH COVID-19 (ortholog); Experimental Liver Cirrhosis (ortholog); Hypotension (ortholog); FOUND IN cytoplasm (ortholog); fibrillar center (ortholog); nucleolus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 17 | 69449483 | 69458478 | Rat | 317 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1564085 | Lats1 | large tumor suppressor kinase 1 | ENCODES a protein that exhibits ATP binding (ortholog); magnesium ion binding (ortholog); nuclear estrogen receptor binding (ortholog); INVOLVED IN regulation of postsynaptic density assembly; G2/M transition of mitotic cell cycle (ortholog); hippo signaling (ortholog); ASSOCIATED WITH basal cell ca rcinoma (ortholog); Ependymomas (ortholog); Glandular and Epithelial Neoplasms (ortholog); FOUND IN glutamatergic synapse; postsynapse; cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 1 | 3980801 | 4014029 | Rat | 177 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1564875 | Ldb3 | LIM domain binding 3 | ENCODES a protein that exhibits enzyme binding; cytoskeletal protein binding (ortholog); muscle alpha-actinin binding (ortholog); INVOLVED IN sarcomere organization (ortholog); PARTICIPATES IN protein kinase C (PKC) signaling pathway; ASSOCIATED WITH arrhythmogenic right ventricular cardiomyopathy ( ortholog); cardiomyopathy (ortholog); congenital myopathy (ortholog); FOUND IN Z disc; cytoskeleton (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; alpha-Zearalanol | 16 | 9862161 | 9926338 | Rat | 157 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 6502346 | LOC100909675 | uncharacterized LOC100909675 | | 4 | 12179988 | 12184203 | Rat | | GenBank Nucleotide | gene, ncrna, VALIDATED [RefSeq] |
| 6496734 | LOC100910802 | uncharacterized LOC100910802 | | 12 | 25379031 | 25394160 | Rat | | GenBank Nucleotide | gene, ncrna, VALIDATED [RefSeq] |
| 3072 | Mdh1 | malate dehydrogenase 1 | ENCODES a protein that exhibits L-malate dehydrogenase (NAD+) activity; malate dehydrogenase activity; NAD binding; INVOLVED IN malate metabolic process; NAD+ metabolic process; oxaloacetate metabolic process; PARTICIPATES IN Leigh disease pathway; nicotinamide adenine dinucleotide metabolic pathway ; primary hyperoxaluria type 2 pathway; ASSOCIATED WITH Liver Injury; Acute Liver Failure (ortholog); adult respiratory distress syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1-benzylpiperazine; 1-naphthyl isothiocyanate; 17beta-estradiol | 14 | 99831934 | 99847227 | Rat | 257 | GenBank Nucleotide | gene, protein-coding, REVIEWED [RefSeq] |
| 1306415 | Med20 | mediator complex subunit 20 | ENCODES a protein that exhibits ubiquitin protein ligase activity; INVOLVED IN protein ubiquitination; skeletal muscle cell differentiation (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; FOUND IN ubiquitin ligase complex; mediator complex (ortholog); nucleus (ortholog); INTERAC TS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; bisphenol A | 9 | 20867681 | 20880288 | Rat | 76 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1310230 | Mff | mitochondrial fission factor | ENCODES a protein that exhibits GTPase binding; protein-containing complex binding; identical protein binding (ortholog); INVOLVED IN cellular response to hydrogen peroxide; positive regulation of cardiac muscle cell apoptotic process; positive regulation of mitochondrial fission; PARTICIPATES IN mi tochondria fission pathway; ASSOCIATED WITH transient cerebral ischemia; encephalopathy due to defective mitochondrial and peroxisomal fission 2 (ortholog); genetic disease (ortholog); FOUND IN mitochondrial membrane; synaptic vesicle; synaptic vesicle membrane; INTERACTS WITH atrazine; benzo[a]pyrene; bisphenol A | 9 | 91455931 | 91484171 | Rat | 179 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 621680 | Mipep | mitochondrial intermediate peptidase | ENCODES a protein that exhibits endopeptidase activity; INVOLVED IN proteolysis (inferred); PARTICIPATES IN presequence pathway of mitochondrial protein import; ASSOCIATED WITH cardiomyopathy (ortholog); combined oxidative phosphorylation deficiency 31 (ortholog); genetic disease (ortholog); FOUND I N mitochondrial matrix; mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 39102301 | 39227915 | Rat | 120 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 620400 | Mlxipl | MLX interacting protein-like | ENCODES a protein that exhibits DNA binding; DNA-binding transcription factor activity; protein kinase binding; INVOLVED IN cellular response to glucose stimulus; energy homeostasis; fatty acid homeostasis; PARTICIPATES IN glycolysis/gluconeogenesis pathway; ASSOCIATED WITH end stage renal disease; Hypertriglyceridemia; Insulin Resistance; FOUND IN cytosol; nucleus; chromatin (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 27178158 | 27213675 | Rat | 313 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 3140 | Myh9 | myosin, heavy chain 9 | ENCODES a protein that exhibits follicle-stimulating hormone receptor binding; G-protein alpha-subunit binding; identical protein binding; INVOLVED IN actin filament bundle assembly; actin filament bundle distribution; cell-cell adhesion; PARTICIPATES IN follicle-stimulating hormone signaling pathwa y; myocarditis pathway; ASSOCIATED WITH Carotid Artery Injuries; metabolic acidosis; AIDS-Associated Nephropathy (ortholog); FOUND IN actin filament; apical plasma membrane; brush border; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol 3-benzoate | 7 | 111224291 | 111304963 | Rat | 450 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1561931 | Nexmif | neurite extension and migration factor | INVOLVED IN negative regulation of cell adhesion mediated by integrin; negative regulation of cell-cell adhesion mediated by cadherin; negative regulation of cell-matrix adhesion; ASSOCIATED WITH autism spectrum disorder (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN nucleopla sm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide | X | 73153786 | 73284943 | Rat | 74 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1308213 | Pbx1 | PBX homeobox 1 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN adrenal gland development (ortholog); animal organ morphogenesis (ortholog); anterior/posterior pattern specification (ortholog); ASSOCIATED WITH brain infarction; glaucoma; autism spectrum disorder (ortholog); FOUND IN cytoplasm (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 13 | 82811664 | 83121447 | Rat | 248 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 3276 | Pctp | phosphatidylcholine transfer protein | ENCODES a protein that exhibits phosphatidylcholine binding (ortholog); phosphatidylcholine transporter activity (ortholog); INVOLVED IN cholesterol metabolic process (ortholog); negative regulation of cold-induced thermogenesis (ortholog); phospholipid transport (ortholog); FOUND IN cytosol (orthol og); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 10 | 75305999 | 75351919 | Rat | 169 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 620393 | Pdp1 | pyruvate dehydrogenase phosphatase catalytic subunit 1 | ENCODES a protein that exhibits calcium ion binding; magnesium ion binding; protein serine/threonine phosphatase activity; INVOLVED IN peptidyl-threonine dephosphorylation (ortholog); positive regulation of pyruvate decarboxylation to acetyl-CoA (ortholog); PARTICIPATES IN pyruvate metabolic pathway ; ASSOCIATED WITH genetic disease (ortholog); obesity (ortholog); Prostatic Neoplasms (ortholog); FOUND IN mitochondrion; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 5 | 30245699 | 30252494 | Rat | 151 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 3311 | Pfkl | phosphofructokinase, liver type | ENCODES a protein that exhibits 6-phosphofructokinase activity; ATP binding; fructose-6-phosphate binding; INVOLVED IN fructose 1,6-bisphosphate metabolic process; fructose 6-phosphate metabolic process; glycolytic process; PARTICIPATES IN glycolysis pathway; glycolysis/gluconeogenesis pathway; fruc tose and mannose metabolic pathway; ASSOCIATED WITH hemolytic anemia (ortholog); FOUND IN 6-phosphofructokinase complex (ortholog); cytosol (ortholog); INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether | 20 | 10663907 | 10685967 | Rat | 276 | GenBank Nucleotide | gene, protein-coding, PROVISIONAL [RefSeq] |
| 68419 | Pfkm | phosphofructokinase, muscle | ENCODES a protein that exhibits 6-phosphofructokinase activity; AMP binding; ATP binding; INVOLVED IN fructose 1,6-bisphosphate metabolic process; fructose 6-phosphate metabolic process; glycolytic process; PARTICIPATES IN Fanconi syndrome pathway; glycogen storage disease type VII pathway; glycolys is pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); genetic disease (ortholog); glycogen storage disease (ortholog); FOUND IN 6-phosphofructokinase complex (ortholog); apical plasma membrane (ortholog); cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-D | 7 | 131100684 | 131138250 | Rat | 284 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 61893 | Pfkp | phosphofructokinase, platelet | ENCODES a protein that exhibits 6-phosphofructokinase activity; ATP binding; fructose-6-phosphate binding; INVOLVED IN fructose 1,6-bisphosphate metabolic process; fructose 6-phosphate metabolic process; glycolytic process; PARTICIPATES IN fructose and mannose metabolic pathway; galactose metabolic pathway; gluconeogenesis pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); syndromic microphthalmia 5 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 17 | 68639749 | 68704055 | Rat | 290 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 3312 | Pgam1 | phosphoglycerate mutase 1 | ENCODES a protein that exhibits phosphoglycerate mutase activity; bisphosphoglycerate mutase activity (ortholog); protein kinase binding (ortholog); INVOLVED IN canonical glycolysis (ortholog); gluconeogenesis (ortholog); PARTICIPATES IN Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficien cy pathway; gluconeogenesis pathway; ASSOCIATED WITH adenocarcinoma (ortholog); Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); FOUND IN neuronal cell body; nucleus; ooplasm; INTERACTS WITH (R,R,R)-alpha-tocopherol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 250673152 | 250680762 | Rat | 250 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1583832 | Pgd | phosphogluconate dehydrogenase | ENCODES a protein that exhibits carbohydrate binding; carboxylic acid binding; NADP binding; INVOLVED IN D-gluconate metabolic process; NADP+ metabolic process; pentose-phosphate shunt; PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - oxidative phase; ribose 5-phosphate isomera se deficiency pathway; ASSOCIATED WITH COVID-19 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH (R)-noradrenaline; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol | 5 | 164865830 | 164882029 | Rat | 277 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 3374 | Ppm1b | protein phosphatase, Mg2+/Mn2+ dependent, 1B | ENCODES a protein that exhibits phosphoprotein phosphatase activity (ortholog); protein serine/threonine phosphatase activity (ortholog); INVOLVED IN N-terminal protein myristoylation (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); negative regulation of defens e response to virus (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; ASSOCIATED WITH hypotonia-cystinuria syndrome (ortholog); Lynch syndrome (ortholog); Myocardial Ischemia (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; aconitine | 6 | 15399559 | 15460301 | Rat | 175 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 3377 | Ppp1cc | protein phosphatase 1 catalytic subunit gamma | ENCODES a protein that exhibits lamin binding; protein domain specific binding; protein phosphatase 1 binding; INVOLVED IN neuron differentiation; positive regulation of glial cell proliferation; blastocyst development (ortholog); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathw ay; dopamine signaling pathway; glycogen biosynthetic pathway; ASSOCIATED WITH congestive heart failure; Spinal Cord Injuries; Ovarian Neoplasms (ortholog); FOUND IN dendritic spine; glutamatergic synapse; postsynapse; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium acetate; ammonium chloride | 12 | 40043822 | 40061301 | Rat | 212 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 3387 | Prkaa1 | protein kinase AMP-activated catalytic subunit alpha 1 | ENCODES a protein that exhibits AMP-activated protein kinase activity; ATP binding; kinase binding; INVOLVED IN cellular response to calcium ion; cellular response to ethanol; cellular response to glucose stimulus; PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pat hway; vascular endothelial growth factor signaling pathway; autophagy pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury; cholestasis; Diabetes Complications; FOUND IN apical plasma membrane; axon; cytoplasm; INTERACTS WITH (+)-schisandrin B; (R,R)-tramadol; 1,2,3,4,7,8-Hexachlorodibenzodioxin | 2 | 55967766 | 56003450 | Rat | 658 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 62047 | Ptbp1 | polypyrimidine tract binding protein 1 | ENCODES a protein that exhibits mRNA binding; regulatory region RNA binding; sequence-specific DNA binding; INVOLVED IN 3'-UTR-mediated mRNA stabilization; cardiac ventricle development; mRNA processing; PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcin oma (ortholog); Experimental Mammary Neoplasms (ortholog); FOUND IN neuron projection terminus; nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 7 | 10493199 | 10502957 | Rat | 177 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1308297 | Rbm26 | RNA binding motif protein 26 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); ASSOCIATED WITH anthracosis (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3-chloropropane-1,2-diol | 15 | 88299378 | 88379365 | Rat | 93 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 2324318 | Rps4x | ribosomal protein S4, X-linked | ENCODES a protein that exhibits structural constituent of ribosome (ortholog); INVOLVED IN response to ethanol; positive regulation of cell population proliferation (ortholog); positive regulation of translation (ortholog); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); FOUND IN ribosome; cytoplasmic ribonucleoprotein granule (ortholog); cytosolic ribosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2-nitrofluorene | X | 71338478 | 71342921 | Rat | 133 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1306706 | Rttn | rotatin | INVOLVED IN determination of left/right symmetry (ortholog); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH bisphenol A; gentamycin; paracetamol | 18 | 84495813 | 84673079 | Rat | 82 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1583843 | S1pr3 | sphingosine-1-phosphate receptor 3 | ENCODES a protein that exhibits integrin binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); inflammatory response (ortholog); negative regulation of establishment of endothelial barrier (ortholog); PARTICIPATES IN sphingosine 1-phosp hate signaling pathway; FOUND IN plasma membrane (ortholog); presynapse (ortholog); INTERACTS WITH acetamide; aldehydo-D-glucose; ammonium chloride | 17 | 13932773 | 13946213 | Rat | 170 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1308369 | Samhd1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 | ENCODES a protein that exhibits deoxynucleoside triphosphate hydrolase activity (ortholog); dGTP binding (ortholog); dGTPase activity (ortholog); INVOLVED IN dATP catabolic process (ortholog); defense response to virus (ortholog); deoxyribonucleotide catabolic process (ortholog); ASSOCIATED WITH acu te myeloid leukemia (ortholog); Aicardi-Goutieres syndrome (ortholog); Aicardi-Goutieres Syndrome 5 (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); site of double-strand break (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil | 3 | 166179742 | 166214448 | Rat | 223 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1308481 | Sdr42e1 | short chain dehydrogenase/reductase family 42E, member 1 | ENCODES a protein that exhibits oxidoreductase activity (inferred); oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (inferred); INVOLVED IN steroid biosynthetic process (inferred); ASSOCIATED WITH acromesomelic dysplasia 4 (ortholog); Experimental Liver Cirrhosi s (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 19 | 62624130 | 62636652 | Rat | 78 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1560377 | Snapin | SNAP-associated protein | ENCODES a protein that exhibits protein-macromolecule adaptor activity (ortholog); SNARE binding (ortholog); INVOLVED IN anterograde axonal transport (ortholog); anterograde synaptic vesicle transport (ortholog); autophagosome maturation (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN glut amatergic synapse; presynapse; secretory granule; INTERACTS WITH acetamide; bisphenol A; cadmium dichloride | 2 | 178269157 | 178271746 | Rat | 145 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1310259 | Ssna1 | SS nuclear autoantigen 1 | ENCODES a protein that exhibits identical protein binding (ortholog); microtubule binding (ortholog); INVOLVED IN axon arborization (ortholog); axon extension (ortholog); axonogenesis (ortholog); FOUND IN axon (ortholog); axoneme (ortholog); centriole (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodi benzodioxine; 2,4,6-trinitrotoluene; 4,4'-sulfonyldiphenol | 3 | 28483107 | 28484571 | Rat | 88 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1303113 | Syap1 | synapse associated protein 1 | INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to insulin stimulus (ortholog); cellular response to insulin-like growth factor stimulus (ortholog); FOUND IN axon (ortholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | X | 35423947 | 35458472 | Rat | 115 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1310907 | Tlk2 | tousled-like kinase 2 | ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cellular response to gamma radiation (ortholog); chromosome segregation (ortholog); DNA damage response (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal dominant intellectual developmental disorder 57 (ortholog); Developmental Disease (ortholog); FOUND IN intermediate filament (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 90648623 | 90748427 | Rat | 127 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 708403 | Tmem176b | transmembrane protein 176B | INVOLVED IN negative regulation of dendritic cell differentiation (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); long QT syndrome (ortholog); FOUND IN membrane (inferred); nuclear membrane (inferred); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 4 | 79097808 | 79105263 | Rat | 119 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 6495353 | Tmem45a | transmembrane protein 45A | ASSOCIATED WITH COVID-19 (ortholog); Lung Neoplasms (ortholog); FOUND IN membrane (inferred); INTERACTS WITH all-trans-retinoic acid; alpha-Zearalanol; bisphenol A | 11 | 57181686 | 57268630 | Rat | 97 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1308940 | Tmod4 | tropomodulin 4 | ENCODES a protein that exhibits tropomyosin binding (ortholog); INVOLVED IN pointed-end actin filament capping (inferred); FOUND IN striated muscle thin filament (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene; 6-propyl-2-thiouracil | 2 | 185384547 | 185389549 | Rat | 73 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 621057 | Tnc | tenascin C | ENCODES a protein that exhibits integrin binding (ortholog); syndecan binding (ortholog); INVOLVED IN bud outgrowth involved in lung branching; cellular response to prostaglandin D stimulus; cellular response to retinoic acid; PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix sig naling pathway; ASSOCIATED WITH cholangiocarcinoma; Experimental Diabetes Mellitus; high grade glioma; FOUND IN extracellular matrix of synaptic cleft; glutamatergic synapse; basement membrane (ortholog); INTERACTS WITH (+)-pilocarpine; 1-naphthyl isothiocyanate; 11-deoxycorticosterone | 5 | 82391340 | 82476197 | Rat | 404 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 621562 | Ubb | ubiquitin B | INVOLVED IN adipose tissue development (ortholog); energy homeostasis (ortholog); fat pad development (ortholog); PARTICIPATES IN Parkinson's disease pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN mitochondrion (ortholog); neuron projection (ortholog); neuronal cell body (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride | 10 | 47746923 | 47748628 | Rat | 152 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1564700 | Ubp1 | upstream binding protein 1 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN angiogenesis (ortholog); negati ve regulation of viral transcription (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,4,7,8-Pentachlorodibenzofuran; bisphenol A; gentamycin | 8 | 122748005 | 122793824 | Rat | 73 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1308045 | Usp12 | ubiquitin specific peptidase 12 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); cysteine-type endopeptidase activity (ortholog); deubiquitinase activity (ortholog); INVOLVED IN protein deubiquitination (ortholog); PARTICIPATES IN histone modification pathway; FOUND IN cytoplasm (ortholog); nucleus (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 12 | 13423625 | 13477547 | Rat | 104 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1593979 | Zfp58 | zinc finger protein 58 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH bisphenol A; (-)-epigallocatechin 3 -gallate (ortholog); 1,2-dimethylhydrazine (ortholog) | 1 | 36848858 | 36861605 | Rat | 37 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1566325 | Zfp874b | zinc finger protein 874b | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred); INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiou racil; amitrole | 1 | 36830702 | 36842705 | Rat | 35 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 61854 | Zranb2 | zinc finger RANBP2-type containing 2 | ENCODES a protein that exhibits metal ion binding (inferred); RNA binding (inferred); zinc ion binding (inferred); INVOLVED IN mRNA processing (inferred); RNA processing (inferred); RNA splicing (inferred); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitr otoluene; 3H-1,2-dithiole-3-thione | 2 | 249232010 | 249245786 | Rat | 101 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 1565468 | Zzz3 | zinc finger, ZZ-type containing 3 | ENCODES a protein that exhibits histone binding (ortholog); INVOLVED IN chromatin organization (ortholog); regulation of cell cycle (ortholog); regulation of cell division (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH pancreatic ductal carcinoma (ort holog); FOUND IN ATAC complex (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH bisphenol A; methimazole; oxaliplatin | 2 | 243990305 | 244057251 | Rat | 97 | GenBank Nucleotide | gene, protein-coding, VALIDATED [RefSeq] |
| 735078 | Lamtor1 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 | ENCODES a protein that exhibits GTPase binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to nutrient levels (ortholog); cholesterol homeostasis (ortholog ); PARTICIPATES IN mTOR signaling pathway; FOUND IN late endosome membrane; membrane raft; FNIP-folliculin RagC/D GAP (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A | 1 | 165684001 | 165689698 | Rat | 136 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1562501 | Lamtor2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); fibroblast migration (ortholog); intracellular protein localization (ortholog); PARTICIPATES IN mTOR signalin g pathway; ASSOCIATED WITH Immunodeficiency due to Defect in MAPBP-Interacting Protein (ortholog); FOUND IN FNIP-folliculin RagC/D GAP (ortholog); late endosome (ortholog); lysosomal membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; acetamide | 2 | 176306353 | 176310617 | Rat | 106 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307133 | Lamtor3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); kinase activator activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); intracellular protein localization (ortholog); positive regulation of M APK cascade (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN FNIP-folliculin RagC/D GAP (ortholog); late endosome (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,6-dinitrotoluene; amphetamine | 2 | 229084795 | 229097028 | Rat | 119 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309735 | Lamtor4 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); positive regulation of TOR signaling (ortholog); positive regulation of TORC1 signaling (ortholog); PARTICIPA TES IN mTOR signaling pathway; FOUND IN FNIP-folliculin RagC/D GAP (ortholog); lysosomal membrane (ortholog); lysosome (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 12 | 22372269 | 22376090 | Rat | 76 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305005 | Lamtor5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); negative regulation of apoptotic process (ortholog); positive regulation of canonical NF-kappaB signal transd uction (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); glucose intolerance (ortholog); FOUND IN cytosol (ortholog); FNIP-folliculin RagC/D GAP (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 197588242 | 197593598 | Rat | 89 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 619804 | Rraga | Ras-related GTP binding A | ENCODES a protein that exhibits GTP binding; GTPase activity (ortholog); phosphoprotein binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to amino acid stimulus (ortholog); cellular response to nutrient levels (ortholog); PARTICIPATES IN mTOR si gnaling pathway; FOUND IN cytoplasm (ortholog); FNIP-folliculin RagC/D GAP (ortholog); GATOR1 complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3H-1,2-dithiole-3-thione | 5 | 106159335 | 106160930 | Rat | 172 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311760 | Rragc | Ras-related GTP binding C | ENCODES a protein that exhibits enzyme-substrate adaptor activity (ortholog); GDP binding (ortholog); GTP binding (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to nutrient levels (ortholog); positive regulation of TORC1 signaling (ortholog); PARTICI PATES IN mTOR signaling pathway; ASSOCIATED WITH follicular lymphoma (ortholog); genetic disease (ortholog); LONG-OLSEN-DISTELMAIER SYNDROME (ortholog); FOUND IN cytoplasm (ortholog); FNIP-folliculin RagC/D GAP (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole | 5 | 141433014 | 141452546 | Rat | 136 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311881 | Slc38a9 | solute carrier family 38, member 9 | ENCODES a protein that exhibits amino acid transmembrane transporter activity (ortholog); arginine binding (ortholog); cholesterol binding (ortholog); INVOLVED IN amino acid transmembrane transport (ortholog); asparagine transport (ortholog); cellular response to amino acid stimulus (ortholog); ASSO CIATED WITH Liver Neoplasms (ortholog); FOUND IN FNIP-folliculin RagC/D GAP (ortholog); late endosome (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 2 | 46024731 | 46102419 | Rat | 105 | description | gene, protein-coding, PROVISIONAL [RefSeq] |