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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of molecular function
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Accession:GO:0044093 term browser browse the term
Definition:Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.


show annotations for term's descendants           Sort by:
activation of adenylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRHR growth hormone releasing hormone receptor ISO RGD PMID:9845677 RGD:1601338 NCBI chr 7:31,582,134...31,592,914
Ensembl chr 7:31,696,914...31,712,200 		JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO RGD PMID:8440169 RGD:2292602 NCBI chr2A:48,808,822...48,879,021
Ensembl chr2A:49,729,002...49,798,780 		JBrowse link
G VIPR2 vasoactive intestinal peptide receptor 2 ISO RGD PMID:8224221 RGD:70054 Ensembl chr 7:162,306,477...162,422,788 JBrowse link
activation of cysteine-type endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:10349840 RGD:9835366 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796 		JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCK cholecystokinin ISO RGD PMID:11964411 RGD:625521 NCBI chr 3:42,168,012...42,176,358
Ensembl chr 3:42,431,022...42,439,396 		JBrowse link
G TNFSF15 TNF superfamily member 15 ISO RGD PMID:11911831 RGD:634236 NCBI chr 9:85,881,800...85,904,191
Ensembl chr 9:114,249,472...114,265,441 		JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD3 SMAD family member 3 ISO TGF-beta1-induced cleavage of BAD to its more active 15 kD form RGD PMID:11839804 RGD:2301029 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185 		JBrowse link
activation of GTPase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF5 eukaryotic translation initiation factor 5 ISO RGD PMID:10805737 RGD:10755758 NCBI chr14:83,960,299...83,969,352
Ensembl chr14:103,773,309...103,783,403 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:15158121 RGD:1642626 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474 		JBrowse link
G RASA1 RAS p21 protein activator 1 ISO RGD PMID:8226805 RGD:9999452 NCBI chr 5:27,980,907...28,104,368
Ensembl chr 5:28,115,159...28,240,321 		JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 ISO RGD PMID:1379346 RGD:10003125 NCBI chr15:57,933,152...58,063,824
Ensembl chr15:76,891,556...77,022,534 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 ISO RGD PMID:18930714 RGD:10043296 NCBI chr21:17,483,273...17,925,301
Ensembl chr21:30,868,308...31,016,883 		JBrowse link
activation of Janus kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:9314843 RGD:6478796 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
G GHR growth hormone receptor ISO RGD PMID:11244571 RGD:1624962 NCBI chr 5:67,654,326...67,953,140
Ensembl chr 5:72,700,150...72,871,278 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:11818507 RGD:633057 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474 		JBrowse link
activation of phospholipase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1R1 ADCYAP receptor type I ISO RGD PMID:8396727 RGD:631732 NCBI chr 7:31,597,251...31,724,299
Ensembl chr 7:31,784,622...31,843,381 		JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO RGD PMID:7935320 RGD:69745 NCBI chr 8:25,947,996...26,138,022
Ensembl chr 8:22,853,677...23,044,388 		JBrowse link
G AGT angiotensinogen ISO RGD PMID:11100981 RGD:1582152 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein ISO RGD PMID:7835339 RGD:68218 NCBI chr 8:12,282,190...12,809,770
Ensembl chr 8:9,037,742...9,460,233 		JBrowse link
G LOC100986730 guanine nucleotide-binding protein G(q) subunit alpha ISO RGD PMID:14981460 RGD:1598489 NCBI chr 9:46,816,409...47,129,116
Ensembl chr 9:76,575,815...76,773,849 		JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:11388899 RGD:1599963 NCBI chr11:55,318,843...55,326,779
Ensembl chr11:58,764,911...58,772,567 		JBrowse link
activation of phospholipase D activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNA13 G protein subunit alpha 13 ISO RGD PMID:12435801 RGD:1598460 NCBI chr17:58,957,682...59,005,182 JBrowse link
G HPCA hippocalcin ISO RGD PMID:11211872 RGD:9686445 NCBI chr 1:32,176,465...32,185,133
Ensembl chr 1:33,363,673...33,371,524 		JBrowse link
G MARCKS myristoylated alanine rich protein kinase C substrate ISO RGD PMID:16341931 RGD:9685306 NCBI chr 6:111,647,847...111,653,821 JBrowse link
G PRKCZ protein kinase C zeta ISO RGD PMID:16113073 RGD:1642674 NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855 		JBrowse link
activation of protein kinase A activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UCN urocortin ISO RGD PMID:19460778 RGD:5508168 NCBI chr2A:27,309,458...27,311,268
Ensembl chr2A:27,397,295...27,397,669 		JBrowse link
activation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADNP activity dependent neuroprotector homeobox ISO Fyn kinase RGD PMID:19047645 RGD:2312772 NCBI chr20:47,233,696...47,276,075
Ensembl chr20:48,361,043...48,400,387 		JBrowse link
G CAMKK1 calcium/calmodulin dependent protein kinase kinase 1 ISO RGD PMID:16054095 RGD:2311420 NCBI chr17:3,908,598...3,941,118
Ensembl chr17:3,900,458...3,930,010 		JBrowse link
G CAMKK2 calcium/calmodulin dependent protein kinase kinase 2 ISO RGD PMID:16054095 RGD:2311420 NCBI chr12:118,835,862...118,896,918
Ensembl chr12:122,206,552...122,267,631 		JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:12086672 RGD:1580677 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G HNF1A HNF1 homeobox A ISO RGD PMID:20841353 RGD:150540305 NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911 		JBrowse link
activation of protein kinase B activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCZ protein kinase C zeta ISO in hepatocytes RGD PMID:15007074 RGD:1642700 NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855 		JBrowse link
activation of store-operated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STIM1 stromal interaction molecule 1 ISO RGD PMID:21541286 RGD:7175076 NCBI chr11:3,726,501...3,954,951
Ensembl chr11:3,840,513...4,065,224 		JBrowse link
G STIM2 stromal interaction molecule 2 ISO RGD PMID:21541286 RGD:7175076 NCBI chr 4:21,262,272...21,424,944
Ensembl chr 4:26,537,703...26,694,416 		JBrowse link
negative regulation of activation of Janus kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNF4A hepatocyte nuclear factor 4 alpha ISO RGD PMID:16584384 RGD:1625011 NCBI chr20:40,684,450...40,763,824
Ensembl chr20:41,779,034...41,856,536 		JBrowse link
negative regulation of guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha ISO RGD PMID:9582312 RGD:1581075 NCBI chr12:121,206,380...121,218,749
Ensembl chr12:125,433,227...125,446,665 		JBrowse link
G EIF2B4 eukaryotic translation initiation factor 2B subunit delta ISO RGD PMID:9582312 RGD:1581075 NCBI chr2A:27,368,189...27,374,265
Ensembl chr2A:27,456,457...27,462,706 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha ISO RGD PMID:9582312 RGD:1581075 NCBI chr14:47,935,691...47,960,055
Ensembl chr14:66,813,953...66,839,866 		JBrowse link
positive regulation of actin filament binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POLDIP2 DNA polymerase delta interacting protein 2 ISO RGD PMID:30354218 RGD:124713558 NCBI chr17:28,416,912...28,427,280
Ensembl chr17:28,919,371...28,928,682 		JBrowse link
positive regulation of adenylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:21143600 RGD:8693686 NCBI chr10:110,642,491...110,646,595 JBrowse link
G AKAP5 A-kinase anchoring protein 5 ISO RGD PMID:20410303 RGD:7242424 NCBI chr14:45,045,476...45,050,946
Ensembl chr14:63,302,200...63,303,483 		JBrowse link
G GCG glucagon ISO RGD PMID:2235678 RGD:11556254 NCBI chr2B:49,436,379...49,446,559
Ensembl chr2B:166,806,016...166,811,155 		JBrowse link
G HPCA hippocalcin ISO RGD PMID:15336960 RGD:9686438 NCBI chr 1:32,176,465...32,185,133
Ensembl chr 1:33,363,673...33,371,524 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:15901773 RGD:1598578 NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649 		JBrowse link
positive regulation of alkaline phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2 integrin subunit alpha 2 ISO RGD PMID:10867645 RGD:2307406 NCBI chr 5:60,935,452...61,040,726
Ensembl chr 5:62,555,370...62,659,720 		JBrowse link
G SMAD3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185 		JBrowse link
positive regulation of AMPA receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 ISO RGD PMID:16093395 RGD:13515081 NCBI chr22:17,475,693...17,618,299
Ensembl chr22:35,317,121...35,454,850 		JBrowse link
G CACNG3 calcium voltage-gated channel auxiliary subunit gamma 3 ISO RGD PMID:12771129 RGD:13515082 Ensembl chr16:24,501,881...24,608,921 JBrowse link
G CACNG4 calcium voltage-gated channel auxiliary subunit gamma 4 ISO RGD PMID:12771129 RGD:13515082 NCBI chr17:60,900,645...60,969,659 JBrowse link
G CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 ISO RGD PMID:12771129 RGD:13515082 NCBI chr19:50,899,256...50,920,028 JBrowse link
positive regulation of ATP-dependent activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:8760245 RGD:8548528 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892 		JBrowse link
G TPM1 tropomyosin 1 ISO RGD PMID:11329279 RGD:1600520 NCBI chr15:41,989,239...42,018,520
Ensembl chr15:60,286,587...60,315,530 		JBrowse link
positive regulation of ATPase-coupled calcium transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGN regucalcin ISO RGD PMID:10797571 RGD:9590178 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881 		JBrowse link
positive regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:31172217 RGD:329403053 NCBI chr 1:143,239,576...143,404,038
Ensembl chr 1:147,023,671...147,129,705 		JBrowse link
positive regulation of catalytic activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11100981 RGD:1582152 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G CDC42 cell division cycle 42 ISO RGD PMID:18562481 RGD:5688290 NCBI chr 1:21,245,970...21,286,210 JBrowse link
G CLPS colipase ISO RGD PMID:8656075 RGD:2303166 NCBI chr 6:35,357,206...35,359,929
Ensembl chr 6:36,559,250...36,561,607 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO Eno1 RGD PMID:21958194 RGD:10059326 NCBI chr11:117,890,545...117,895,262
Ensembl chr11:121,809,800...121,815,773 		JBrowse link
G NGB neuroglobin ISO RGD PMID:23036890 RGD:9743969 NCBI chr14:57,818,491...57,824,196
Ensembl chr14:77,020,274...77,025,983 		JBrowse link
G NPM1 nucleophosmin 1 ISO DNA polymerase alpha RGD PMID:11481036 RGD:1600909 NCBI chr 5:166,735,904...166,756,321
Ensembl chr 5:173,490,197...173,510,656 		JBrowse link
G NPM2 nucleophosmin/nucleoplasmin 2 ISO DNA polymerase alpha, lesser effect than Npm1 RGD PMID:11481036 RGD:1600909 NCBI chr 8:21,268,873...21,281,684
Ensembl chr 8:18,208,934...18,221,577 		JBrowse link
positive regulation of cation channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:22505670 RGD:6893581 NCBI chr10:110,642,491...110,646,595 JBrowse link
G ASIC2 acid sensing ion channel subunit 2 ISO RGD PMID:12736332 RGD:1298620 NCBI chr17:22,628,322...23,774,249 JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:20806410 RGD:9686372 NCBI chr 5:64,673,392...65,116,259
Ensembl chr 5:69,724,767...70,158,761 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO RGD PMID:23785408 RGD:7296920 NCBI chr11:17,440,522...17,444,075
Ensembl chr11:17,127,557...17,128,729 		JBrowse link
G NTSR1 neurotensin receptor 1 ISO RGD PMID:19359367 RGD:9743912 NCBI chr20:59,100,110...59,151,563
Ensembl chr20:60,392,736...60,446,056 		JBrowse link
positive regulation of chromatin binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KAT2B lysine acetyltransferase 2B ISO Ep300 RGD PMID:20870727 RGD:9590266 NCBI chr 3:19,956,067...20,070,637
Ensembl chr 3:20,286,865...20,400,770 		JBrowse link
G KDM1A lysine demethylase 1A ISO RGD PMID:20418916 RGD:9588315 NCBI chr 1:22,205,624...22,269,571
Ensembl chr 1:23,153,066...23,217,692 		JBrowse link
G MBD2 methyl-CpG binding domain protein 2 ISO RGD PMID:25135974 RGD:9589119 NCBI chr18:47,534,356...47,609,481 JBrowse link
G MFN2 mitofusin 2 ISO Tfap2a RGD PMID:27997345 RGD:12910740 NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077 		JBrowse link
positive regulation of collagen binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITGA2 integrin subunit alpha 2 ISO epithelial cell binding mediated by syndecan-2 RGD PMID:19394307 RGD:2307393 NCBI chr 5:60,935,452...61,040,726
Ensembl chr 5:62,555,370...62,659,720 		JBrowse link
positive regulation of CREB transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1D calcium voltage-gated channel subunit alpha1 D ISO RGD PMID:16706838 RGD:6906921 NCBI chr 3:53,432,189...53,751,347
Ensembl chr 3:54,495,952...54,970,444 		JBrowse link
positive regulation of cyclic-nucleotide phosphodiesterase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNAT1 G protein subunit alpha transducin 1 ISO RGD PMID:7878085 RGD:1599022 NCBI chr 3:50,119,267...50,126,131
Ensembl chr 3:51,354,472...51,360,568 		JBrowse link
positive regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC6 cell division cycle 6 ISO RGD PMID:22223646 RGD:10045360 NCBI chr17:16,987,721...17,002,488
Ensembl chr17:17,211,681...17,225,972 		JBrowse link
G CDK5RAP1 CDK5 regulatory subunit associated protein 1 ISO RGD PMID:10721722 RGD:632478 NCBI chr20:29,648,003...29,690,210
Ensembl chr20:30,762,967...30,804,237 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO RGD PMID:22223646 RGD:10045360 NCBI chr12:12,742,258...12,747,404
Ensembl chr12:13,120,306...13,125,541 		JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO RGD PMID:15105833 RGD:2313858 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602 		JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:19171933 RGD:5510006 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155 		JBrowse link
G CCN2 cellular communication network factor 2 ISO caspase 3/7 RGD PMID:19625611 RGD:2314487 NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077 		JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:15519734 RGD:8662904 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612 		JBrowse link
G HSF1 heat shock transcription factor 1 ISO RGD PMID:21192280 RGD:10403035 NCBI chr 8:141,055,310...141,078,360
Ensembl chr 8:144,062,137...144,067,866 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO RGD PMID:14522843 RGD:2304239 NCBI chr 5:175,437,167...175,495,469
Ensembl chr 5:182,748,381...182,795,135 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:18322138 RGD:8693423 NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786 		JBrowse link
G PYCARD PYD and CARD domain containing ISO RGD PMID:19401709 RGD:5491174 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828 		JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:17425560 RGD:1642961 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G WDR35 WD repeat domain 35 ISO RGD PMID:20193664 RGD:11553917 NCBI chr2A:19,896,498...19,977,295
Ensembl chr2A:20,014,127...20,093,810 		JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNF tumor necrosis factor ISO RGD PMID:12131680 RGD:14995454 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
positive regulation of cytochrome-c oxidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:15107407 RGD:1578311 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016 		JBrowse link
G MYO5A myosin VA ISO RGD PMID:29217155 RGD:42721980 NCBI chr15:31,246,192...31,470,040
Ensembl chr15:49,578,491...49,704,319 		JBrowse link
positive regulation of DNA binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EP300 E1A binding protein p300 ISO RGD PMID:19057620 RGD:2311715 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604 		JBrowse link
G ITGA2 integrin subunit alpha 2 ISO DNA binding by NF-kappaB RGD PMID:19239475 RGD:2307394 NCBI chr 5:60,935,452...61,040,726
Ensembl chr 5:62,555,370...62,659,720 		JBrowse link
G JAK2 Janus kinase 2 ISO Stat3 RGD PMID:15322111 RGD:1641932 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:12873812 RGD:10059626 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 ISO RGD PMID:11181516 RGD:2311195 NCBI chr13:9,199,572...9,206,202 JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:16272348 RGD:1598594 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNRNPU heterogeneous nuclear ribonucleoprotein U ISO RGD PMID:20554522 RGD:10058983 NCBI chr 1:220,450,218...220,461,412
Ensembl chr 1:225,817,899...225,842,031 		JBrowse link
positive regulation of DNA-binding transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EP300 E1A binding protein p300 ISO RGD PMID:19057620 RGD:2311715 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit ISO RGD PMID:12371906 RGD:629541 NCBI chr11:61,252,513...61,261,032
Ensembl chr11:64,581,841...64,589,304 		JBrowse link
G HMGA2 high mobility group AT-hook 2 ISO RGD PMID:9311991 RGD:1601604 NCBI chr12:22,954,946...23,096,623 JBrowse link
G JAK2 Janus kinase 2 ISO Stat3 RGD PMID:15322111 RGD:1641932 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626 		JBrowse link
G NCOA3 nuclear receptor coactivator 3 ISO RGD PMID:11713241 RGD:727330 NCBI chr20:43,838,227...43,992,407
Ensembl chr20:45,000,422...45,073,549 		JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:16272348 RGD:1598594 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
G UBE2I ubiquitin conjugating enzyme E2 I ISO glucocorticoid receptor, independent of sumoylation activity or presence of a GME RGD PMID:11812797 RGD:2301354 Ensembl chr16:1,367,288...1,382,575 JBrowse link
positive regulation of DNA-directed DNA polymerase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPM1 nucleophosmin 1 ISO RGD PMID:8123045 RGD:11535022 NCBI chr 5:166,735,904...166,756,321
Ensembl chr 5:173,490,197...173,510,656 		JBrowse link
positive regulation of dUTP diphosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGN regucalcin ISO RGD PMID:1315924 RGD:2301218 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881 		JBrowse link
positive regulation of endopeptidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKIRIN2 akirin 2 ISO MMP-9 RGD PMID:18460465 RGD:2306009 NCBI chr 6:85,549,728...85,577,114 JBrowse link
positive regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor ISO RGD PMID:19574994 RGD:2317913 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760 		JBrowse link
positive regulation of glucokinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DUSP12 dual specificity phosphatase 12 ISO increases glucokinase activity by direct dephosphorylation RGD PMID:10913113 RGD:68242 NCBI chr 1:137,161,774...137,169,503
Ensembl chr 1:140,959,867...140,968,821 		JBrowse link
G PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 ISO RGD PMID:15047617 RGD:2302684 NCBI chr  X:47,143,081...47,209,034
Ensembl chr  X:55,374,807...55,441,024 		JBrowse link
G PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 ISO RGD PMID:16980436 RGD:2304071 NCBI chr 1:182,655,487...182,683,881
Ensembl chr 1:186,934,446...186,961,995 		JBrowse link
positive regulation of glutamate-cysteine ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCLM glutamate-cysteine ligase modifier subunit ISO RGD PMID:16137247 RGD:1582663 NCBI chr 1:96,548,850...96,573,273
Ensembl chr 1:95,278,665...95,297,893 		JBrowse link
positive regulation of GTP binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAPGEF3 Rap guanine nucleotide exchange factor 3 ISO Ran-GTP RGD PMID:18689492 RGD:9835375 NCBI chr12:40,974,756...40,999,471
Ensembl chr12:41,848,785...41,873,252 		JBrowse link
positive regulation of GTPase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 ISO RGD PMID:9348539 RGD:631926 NCBI chr2B:33,168,767...33,228,075
Ensembl chr2B:127,716,550...127,775,378 		JBrowse link
G GNAO1 G protein subunit alpha o1 ISO RGD PMID:7544301 RGD:2302012 NCBI chr16:36,473,852...36,643,789
Ensembl chr16:55,606,920...55,776,619 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:17662049 RGD:7240703 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605 		JBrowse link
G LOC100995139 amphiphysin ISO RGD PMID:9348539 RGD:631926 NCBI chr 7:39,015,699...39,262,120
Ensembl chr 7:39,250,081...39,495,844 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO basal and EGF-activated Rac1 RGD PMID:17183546 RGD:2292641 NCBI chr15:45,337,117...45,438,826
Ensembl chr15:63,613,961...63,714,161 		JBrowse link
G RAP1GDS1 Rap1 GTPase-GDP dissociation stimulator 1 ISO RGD PMID:18348285 RGD:2314690 NCBI chr 4:90,671,891...90,846,501
Ensembl chr 4:101,336,286...101,510,517 		JBrowse link
G RASA1 RAS p21 protein activator 1 ISO RGD PMID:14707121 RGD:9999423 NCBI chr 5:27,980,907...28,104,368
Ensembl chr 5:28,115,159...28,240,321 		JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 ISO RGD PMID:15798216 RGD:10003119 NCBI chr15:57,933,152...58,063,824
Ensembl chr15:76,891,556...77,022,534 		JBrowse link
G RGN regucalcin ISO RGD PMID:11693188 RGD:9590216 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881 		JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:9430692 PMID:20530129 RGD:7207369 RGD:7207375 NCBI chr 1:138,488,317...138,496,497
Ensembl chr 1:142,284,040...142,292,225 		JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 ISO RGD PMID:14711826 RGD:1304283 NCBI chr 1:103,893,199...103,898,381
Ensembl chr 1:102,608,839...102,609,987 		JBrowse link
positive regulation of guanylate cyclase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GUCA1A guanylate cyclase activator 1A ISO RGD PMID:12545196 RGD:1599357 NCBI chr 6:41,693,593...41,774,591
Ensembl chr 6:43,045,307...43,070,520 		JBrowse link
positive regulation of high voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:22187436 RGD:13514092 NCBI chr12:39,918,022...39,931,386
Ensembl chr12:40,797,293...40,811,409 		JBrowse link
positive regulation of hydrolase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FABP1 fatty acid binding protein 1 ISO peroxisomal medium- and long-chain acyl-CoA thioesterases RGD PMID:16262600 RGD:1626442 NCBI chr2A:87,256,032...87,303,505
Ensembl chr2A:89,165,315...89,170,448 		JBrowse link
G GM2A ganglioside GM2 activator ISO Phospholipase D RGD PMID:9770472 RGD:1598995 NCBI chr 5:146,680,277...146,696,505
Ensembl chr 5:152,680,696...152,697,018 		JBrowse link
positive regulation of ion transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTR3A 5-hydroxytryptamine receptor 3A ISO RGD PMID:10854267 RGD:61635 NCBI chr11:108,851,954...108,869,119
Ensembl chr11:112,695,891...112,711,695 		JBrowse link
G HTR3B 5-hydroxytryptamine receptor 3B ISO RGD PMID:10854267 RGD:61635 NCBI chr11:108,783,514...108,825,266
Ensembl chr11:112,624,864...112,671,439 		JBrowse link
positive regulation of isoleucine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPL5 ribosomal protein L5 ISO RGD PMID:1665486 RGD:11040680 NCBI chr 1:95,497,047...95,507,006
Ensembl chr 1:94,230,451...94,241,522 		JBrowse link
positive regulation of JUN kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1B interleukin 1 beta ISO RGD PMID:12667655 RGD:1626684 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO RGD PMID:12667655 RGD:1626684 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chr 5:57,116,405...57,197,017
Ensembl chr 5:58,745,579...58,826,959 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:20716917 RGD:10412640 NCBI chr 6:134,316,841...134,582,843
Ensembl chr 6:138,406,398...138,641,727 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:15226266 RGD:1642623 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474 		JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25825749 RGD:11537351 NCBI chr 9:62,782,183...63,005,626
Ensembl chr 9:90,851,983...90,965,084 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 ISO RGD PMID:16203995 RGD:10043312 NCBI chr21:17,483,273...17,925,301
Ensembl chr21:30,868,308...31,016,883 		JBrowse link
positive regulation of large conductance calcium-activated potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKG1 protein kinase cGMP-dependent 1 ISO RGD PMID:23407708 RGD:7777099 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882 		JBrowse link
positive regulation of MAP kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSK C-terminal Src kinase ISO RGD PMID:10884975 RGD:5134370 NCBI chr15:53,724,814...53,745,710
Ensembl chr15:73,342,703...73,363,476 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO RGD PMID:15087293 RGD:1624373 NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826 		JBrowse link
G ILK integrin linked kinase ISO inhibits Gsk3b which in turn inhibits Erk/Mapk3 activation RGD PMID:17182785 RGD:2301767 NCBI chr11:6,735,735...6,742,922
Ensembl chr11:6,418,717...6,425,788 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 ISO RGD PMID:23987506 RGD:11049533 NCBI chr15:69,076,025...69,190,082
Ensembl chr15:88,276,851...88,388,594 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO RGD PMID:10969813 RGD:1600497 NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9110999 RGD:2293488 NCBI chr 5:57,116,405...57,197,017
Ensembl chr 5:58,745,579...58,826,959 		JBrowse link
G PRKCD protein kinase C delta ISO RGD PMID:16935468 RGD:1642549 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:11941412 RGD:150523765 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634 		JBrowse link
G TAB1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 ISO RGD PMID:21607062 RGD:5508182 NCBI chr22:20,303,547...20,343,314
Ensembl chr22:38,122,835...38,162,705 		JBrowse link
positive regulation of methionine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPL5 ribosomal protein L5 ISO RGD PMID:1665486 RGD:11040680 NCBI chr 1:95,497,047...95,507,006
Ensembl chr 1:94,230,451...94,241,522 		JBrowse link
positive regulation of microtubule binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSF1 heat shock transcription factor 1 ISO RGD PMID:21229611 RGD:10403032 NCBI chr 8:141,055,310...141,078,360
Ensembl chr 8:144,062,137...144,067,866 		JBrowse link
positive regulation of mRNA binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HNRNPL heterogeneous nuclear ribonucleoprotein L ISO RGD PMID:19273590 RGD:9999430 NCBI chr19:35,943,720...35,959,795 JBrowse link
positive regulation of NAD(P)H oxidase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:27912212 RGD:13507308 NCBI chr 3:50,154,731...50,187,948
Ensembl chr 3:51,398,981...51,421,988 		JBrowse link
G GNAI3 G protein subunit alpha i3 ISO RGD PMID:27912212 RGD:13507308 NCBI chr 1:111,925,668...111,971,941
Ensembl chr 1:111,154,060...111,198,768 		JBrowse link
G LOC100986914 cytochrome b-245 light chain ISO RGD PMID:12631082 RGD:11040676 NCBI chr16:69,356,396...69,364,225
Ensembl chr16:89,016,349...89,024,719 		JBrowse link
positive regulation of NF-kappaB transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMH anti-Mullerian hormone ISO RGD PMID:11356848 RGD:70295 NCBI chr19:1,260,219...1,263,395 JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:19211730 RGD:5130956 NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:9062344 RGD:1600239 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta ISO RGD PMID:15939736 RGD:7495757 NCBI chr 8:41,515,613...41,576,229
Ensembl chr 8:38,960,594...39,020,971 		JBrowse link
G ITGB2 integrin subunit beta 2 ISO RGD PMID:9062344 RGD:1600239 NCBI chr21:31,181,228...31,216,033
Ensembl chr21:44,470,999...44,505,963 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO RGD PMID:14576830 RGD:1600488 NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335 		JBrowse link
G TGFB1 transforming growth factor beta 1 ISO RGD PMID:15781474 RGD:1579751 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973 		JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:16651628 RGD:1598593 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
G TNFRSF8 TNF receptor superfamily member 8 ISO RGD PMID:8982082 RGD:730027 NCBI chr 1:10,813,111...10,893,005
Ensembl chr 1:12,029,038...12,108,495 		JBrowse link
G TRAF2 TNF receptor associated factor 2 ISO RGD PMID:10713108 RGD:2298798 NCBI chr 9:107,938,935...107,984,797
Ensembl chr 9:136,917,358...136,955,331 		JBrowse link
positive regulation of nitric-oxide synthase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALM1 calmodulin 1 ISO RGD PMID:20529840 RGD:7241266 NCBI chr14:71,015,099...71,026,322
Ensembl chr19:52,121,687...52,131,135 		JBrowse link
G CALM2 calmodulin 2 ISO RGD PMID:20529840 RGD:7241266 NCBI chr2A:47,274,722...47,290,861
Ensembl chr2A:48,204,518...48,220,697 		JBrowse link
G CALM3 calmodulin 3 ISO RGD PMID:20529840 RGD:7241266 NCBI chr19:43,593,069...43,602,550
Ensembl chr19:52,121,687...52,131,135 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO RGD PMID:14576830 RGD:1600488 NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 ISO RGD PMID:22870324 RGD:9831169 NCBI chr 7:31,060,245...31,109,012
Ensembl chr 7:31,182,275...31,208,742 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:21926342 RGD:10041069 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474 		JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:9537427 RGD:14985259 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
positive regulation of NMDA glutamate receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFL1 cofilin 1 ISO RGD PMID:24089484 RGD:11570552 NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806 		JBrowse link
G PINK1 PTEN induced kinase 1 ISO RGD PMID:20698836 RGD:13463453 NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560 		JBrowse link
G RGS9 regulator of G protein signaling 9 ISO RGD PMID:16510730 RGD:1599994 NCBI chr17:59,085,707...59,176,368
Ensembl chr17:64,262,585...64,389,559 		JBrowse link
positive regulation of oxidative phosphorylation uncoupler activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC25A4 solute carrier family 25 member 4 ISO RGD PMID:18251717 RGD:7242053 NCBI chr 4:177,310,982...177,315,016
Ensembl chr 4:189,531,914...189,534,549 		JBrowse link
positive regulation of oxidoreductase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FDX1 ferredoxin 1 ISO p-nitrophenol hydroxylase, dimethylnitrosamine demethylase RGD PMID:11325963 RGD:4145669 NCBI chr11:105,311,613...105,345,414 JBrowse link
positive regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNM2 dynamin 2 ISO RGD PMID:12205083 RGD:727418 NCBI chr19:10,272,172...10,386,032
Ensembl chr19:10,933,672...11,106,478 		JBrowse link
positive regulation of phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGN regucalcin ISO RGD PMID:9671264 RGD:9590174 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881 		JBrowse link
G RPL5 ribosomal protein L5 ISO RGD PMID:7649987 RGD:2316860 NCBI chr 1:95,497,047...95,507,006
Ensembl chr 1:94,230,451...94,241,522 		JBrowse link
positive regulation of phospholipase A2 activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2B calcium/calmodulin dependent protein kinase II beta ISO RGD PMID:15576376 RGD:6482753 NCBI chr 7:44,930,859...45,040,078
Ensembl chr 7:45,001,267...45,110,342 		JBrowse link
positive regulation of phospholipase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPCA hippocalcin ISO RGD PMID:11211872 RGD:9686445 NCBI chr 1:32,176,465...32,185,133
Ensembl chr 1:33,363,673...33,371,524 		JBrowse link
positive regulation of phospholipase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTAFR platelet activating factor receptor ISO RGD PMID:8798508 RGD:9999203 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861 		JBrowse link
positive regulation of phosphoprotein phosphatase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JAK2 Janus kinase 2 ISO Ptpn11 activity RGD PMID:17021051 RGD:1641809 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626 		JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:23219599 RGD:9835413 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:24265448 RGD:8693600 NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786 		JBrowse link
positive regulation of potassium ion transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor ISO RGD PMID:23212096 RGD:7244285 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
positive regulation of potassium:proton exchanging ATPase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAPGEF3 Rap guanine nucleotide exchange factor 3 ISO RGD PMID:11897793 RGD:625394 NCBI chr12:40,974,756...40,999,471
Ensembl chr12:41,848,785...41,873,252 		JBrowse link
positive regulation of protein binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR3 actin related protein 3 ISO Npc1l1, Rab11a, Myo5b RGD PMID:21844200 RGD:5688279 NCBI chr2B:827,184...900,424
Ensembl chr2B:114,373,392...114,445,729 		JBrowse link
G CALD1 caldesmon 1 ISO RGD PMID:3384851 RGD:2303065 NCBI chr 7:126,743,466...126,935,412
Ensembl chr 7:139,337,692...139,440,643 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 ISO Akt1-Hsp90 RGD PMID:18443201 RGD:4108490 NCBI chr 6:43,842,796...43,849,637
Ensembl chr 6:45,125,773...45,133,872 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO RGD PMID:11415446 RGD:4892111 NCBI chr 5:128,463,186...128,517,563
Ensembl chr 5:134,619,076...134,673,658 		JBrowse link
G LOC100990116 phosphofurin acidic cluster sorting protein 1 ISO RGD PMID:9695949 RGD:633354 NCBI chr11:61,434,702...61,633,334
Ensembl chr11:64,884,048...64,935,947
Ensembl chr11:64,884,048...64,935,947 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta ISO RGD PMID:7908909 RGD:633201 NCBI chr16:68,063,869...68,076,772 JBrowse link
G PLK2 polo like kinase 2 ISO Sipa1l1 binding to Btcr and Fbxw11 RGD PMID:18723513 RGD:7241135 NCBI chr 5:55,543,828...55,550,116
Ensembl chr 5:57,177,836...57,184,793 		JBrowse link
G RAMP1 receptor activity modifying protein 1 ISO RGD PMID:11556887 RGD:1299115 NCBI chr2B:125,092,164...125,144,032
Ensembl chr2B:243,942,771...243,995,221 		JBrowse link
G RAMP2 receptor activity modifying protein 2 ISO RGD PMID:11556887 RGD:1299115 NCBI chr17:14,554,888...14,557,175
Ensembl chr17:14,779,666...14,781,481 		JBrowse link
G TRIM28 tripartite motif containing 28 ISO RGD PMID:12748187 RGD:1299608 NCBI chr19:55,557,130...55,563,802
Ensembl chr19:64,371,477...64,377,144 		JBrowse link
positive regulation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXIN1 axin 1 ISO RGD PMID:15228590 RGD:1304344 Ensembl chr16:278,239...337,891 JBrowse link
G AXIN2 axin 2 ISO RGD PMID:9566905 RGD:68736 NCBI chr17:59,476,336...59,509,358
Ensembl chr17:64,688,416...64,720,086 		JBrowse link
G CAMKK1 calcium/calmodulin dependent protein kinase kinase 1 ISO RGD PMID:7642608 RGD:632489 NCBI chr17:3,908,598...3,941,118
Ensembl chr17:3,900,458...3,930,010 		JBrowse link
G CCNB1 cyclin B1 ISO histone H1 RGD PMID:15291744 RGD:1578405 NCBI chr 5:44,826,103...44,836,832
Ensembl chr 5:46,394,362...46,405,332 		JBrowse link
G DAG1 dystroglycan 1 ISO RGD PMID:18556591 RGD:11541067 NCBI chr 3:49,396,180...49,464,689
Ensembl chr 3:50,640,615...50,703,852 		JBrowse link
G DAXX death domain associated protein ISO RGD PMID:21572393 RGD:9587767 NCBI chr 6:32,890,846...32,895,307
Ensembl chr 6:34,004,543...34,008,717 		JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A ISO RGD PMID:9653190 RGD:8554053 NCBI chr 7:86,863,919...87,251,634
Ensembl chr 7:100,455,357...100,833,220 		JBrowse link
G SDC4 syndecan 4 ISO RGD PMID:12571249 RGD:1580031 NCBI chr20:41,656,406...41,679,549
Ensembl chr20:42,746,281...42,769,737 		JBrowse link
positive regulation of protein kinase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MARCKS myristoylated alanine rich protein kinase C substrate ISO RGD PMID:16341931 RGD:9685306 NCBI chr 6:111,647,847...111,653,821 JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:25825749 RGD:11537351 NCBI chr 9:62,782,183...63,005,626
Ensembl chr 9:90,851,983...90,965,084 		JBrowse link
positive regulation of protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSP90AB1 heat shock protein 90 alpha family class B member 1 ISO Akt1 RGD PMID:18443201 RGD:4108490 NCBI chr 6:43,842,796...43,849,637
Ensembl chr 6:45,125,773...45,133,872 		JBrowse link
positive regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POLDIP2 DNA polymerase delta interacting protein 2 ISO RGD PMID:30726115 RGD:124713559 NCBI chr17:28,416,912...28,427,280
Ensembl chr17:28,919,371...28,928,682 		JBrowse link
positive regulation of store-operated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 ISO RGD PMID:20844246 RGD:8801954 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752 		JBrowse link
positive regulation of superoxide dismutase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RGN regucalcin ISO RGD PMID:15375603 RGD:9590277 NCBI chr  X:39,513,135...39,530,188
Ensembl chr  X:47,371,226...47,388,881 		JBrowse link
positive regulation of threonine-tRNA ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPL5 ribosomal protein L5 ISO RGD PMID:8049265 RGD:1556518 NCBI chr 1:95,497,047...95,507,006
Ensembl chr 1:94,230,451...94,241,522 		JBrowse link
positive regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO RGD PMID:20478999 RGD:13514093 NCBI chr 7:73,917,439...74,410,627
Ensembl chr 7:87,579,004...88,068,482 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chr12:39,918,022...39,931,386
Ensembl chr12:40,797,293...40,811,409 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 ISO RGD PMID:12821675 RGD:737839 NCBI chr2B:39,137,777...39,399,007
Ensembl chr2B:156,379,469...156,639,328 		JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO RGD PMID:14679187 RGD:7243967 NCBI chr21:20,818,395...20,884,053
Ensembl chr21:34,190,043...34,190,441 		JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 ISO RGD PMID:14679187 RGD:7243967 NCBI chr11:69,527,663...69,540,236
Ensembl chr11:72,835,048...72,835,359 		JBrowse link
G LOC106634235 uncharacterized LOC106634235 ISO RGD PMID:14679187 RGD:7243967 NCBI chr21:20,548,631...20,739,999
Ensembl chr21:34,107,443...34,107,814
Ensembl chr21:34,107,443...34,107,814 		JBrowse link
G S100A1 S100 calcium binding protein A1 ISO RGD PMID:19657060 RGD:7205633 NCBI chr 1:128,984,296...128,987,979 JBrowse link
positive regulation of voltage-gated chloride channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLCN2 chloride voltage-gated channel 2 ISO RGD PMID:29344669 RGD:213230158 NCBI chr 3:181,383,608...181,399,200
Ensembl chr 3:189,862,489...189,881,049 		JBrowse link
G PTAFR platelet activating factor receptor ISO RGD PMID:8168510 RGD:61717 NCBI chr 1:27,405,880...27,436,184
Ensembl chr 1:28,447,833...28,448,861 		JBrowse link
positive regulation of voltage-gated potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO RGD PMID:12183335 RGD:728122 NCBI chr11:17,447,564...17,531,513
Ensembl chr11:17,133,063...17,216,870 		JBrowse link
G AMIGO1 adhesion molecule with Ig like domain 1 ISO RGD PMID:22056818 RGD:14390155 NCBI chr 1:111,881,753...111,887,308
Ensembl chr 1:111,113,632...111,115,113 		JBrowse link
G KCNA1 potassium voltage-gated channel subfamily A member 1 ISO RGD PMID:21943416 RGD:7242916 NCBI chr12:5,027,333...5,037,136
Ensembl chr12:4,950,938...4,952,425 		JBrowse link
G KCNC1 potassium voltage-gated channel subfamily C member 1 ISO RGD PMID:21943417 RGD:12910700 NCBI chr11:17,788,010...17,936,591
Ensembl chr11:17,472,158...17,517,892 		JBrowse link
G KCNC2 potassium voltage-gated channel subfamily C member 2 ISO RGD PMID:21943417 RGD:12910700 NCBI chr12:72,566,924...72,736,270 JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 ISO RGD PMID:7568179 RGD:12910723 NCBI chr21:20,818,395...20,884,053
Ensembl chr21:34,190,043...34,190,441 		JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 ISO RGD PMID:31347976 RGD:151347452 NCBI chr2A:26,688,938...26,729,860
Ensembl chr2A:26,780,475...26,819,123 		JBrowse link
positive regulation of voltage-gated sodium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPER1 G protein-coupled estrogen receptor 1 ISO RGD PMID:24097558 RGD:39939085 NCBI chr 7:1,331,586...1,338,194 JBrowse link
G KIF5B kinesin family member 5B ISO RGD PMID:24198377 RGD:11073607 NCBI chr10:32,138,964...32,186,448
Ensembl chr10:32,731,150...32,778,242 		JBrowse link
receptor transactivation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 ISO RGD PMID:25232008 RGD:13703036 NCBI chr2A:9,478,080...9,545,363
Ensembl chr2A:9,641,201...9,708,054 		JBrowse link
Term paths to the root