DAG1 (dystroglycan 1) - Rat Genome Database
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Gene: DAG1 (dystroglycan 1) Pan paniscus
Analyze
Symbol: DAG1
Name: dystroglycan 1
RGD ID: 11744372
Description: ENCODES a protein that exhibits actin binding (ortholog); alpha-actinin binding (ortholog); dystroglycan binding (ortholog); INVOLVED IN aging (ortholog); angiogenesis involved in wound healing (ortholog); axon regeneration (ortholog); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2D (ortholog); autosomal recessive limb-girdle muscular dystrophy type 2P (ortholog); Bronchopulmonary Dysplasia (ortholog); FOUND IN adherens junction (ortholog); basement membrane (ortholog); basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: dystroglycan
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1350,637,707 - 50,703,852 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,640,615 - 50,703,852 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0349,396,180 - 49,464,689 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
angiogenesis involved in wound healing  (ISO)
axon regeneration  (ISO)
basement membrane organization  (ISO)
branching involved in salivary gland morphogenesis  (ISO)
calcium-dependent cell-matrix adhesion  (ISO)
cellular response to cholesterol  (ISO)
cellular response to mechanical stimulus  (ISO)
commissural neuron axon guidance  (ISO)
epithelial tube branching involved in lung morphogenesis  (ISO)
membrane protein ectodomain proteolysis  (ISO)
microtubule anchoring  (ISO)
modulation by virus of host process  (ISO)
morphogenesis of an epithelial sheet  (ISO)
myelination in peripheral nervous system  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of MAPK cascade  (ISO)
negative regulation of protein kinase B signaling  (ISO)
nerve development  (ISO)
nerve maturation  (ISO)
positive regulation of basement membrane assembly involved in embryonic body morphogenesis  (ISO)
positive regulation of cell-matrix adhesion  (ISO)
positive regulation of myelination  (ISO)
positive regulation of oligodendrocyte differentiation  (ISO)
positive regulation of protein kinase activity  (ISO)
regulation of epithelial to mesenchymal transition  (ISO)
regulation of gastrulation  (ISO)
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane  (ISO)
regulation of synapse organization  (ISO)
response to denervation involved in regulation of muscle adaptation  (ISO)
response to peptide hormone  (ISO)
retrograde trans-synaptic signaling by trans-synaptic protein complex  (ISO)
Schwann cell development  (ISO)
Schwann cell differentiation  (ISO)
skeletal muscle tissue regeneration  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
DAG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1350,637,707 - 50,703,852 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,640,615 - 50,703,852 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0349,396,180 - 49,464,689 (+)NCBIMhudiblu_PPA_v0panPan3
DAG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl349,468,703 - 49,535,618 (+)EnsemblGRCh38hg38GRCh38
GRCh38349,468,703 - 49,535,618 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37349,506,136 - 49,573,051 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,482,569 - 49,548,052 (+)NCBINCBI36hg18NCBI36
Build 34349,482,594 - 49,548,048NCBI
Celera349,470,589 - 49,537,675 (+)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,565,602 - 49,632,289 (+)NCBIHuRef
CHM1_1349,458,558 - 49,525,426 (+)NCBICHM1_1
Dag1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,082,060 - 108,141,176 (-)NCBIGRCm39mm39
GRCm39 Ensembl9108,081,833 - 108,141,157 (-)Ensembl
GRCm389108,204,861 - 108,263,977 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,204,634 - 108,263,958 (-)EnsemblGRCm38mm10GRCm38
MGSCv379108,108,289 - 108,166,067 (-)NCBIGRCm37mm9NCBIm37
MGSCv369108,064,059 - 108,121,837 (-)NCBImm8
Celera9107,814,579 - 107,872,572 (-)NCBICelera
Cytogenetic Map9F1- F2NCBI
cM Map959.08NCBI
Dag1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28108,890,926 - 108,955,611 (-)NCBI
Rnor_6.0 Ensembl8116,980,497 - 116,993,193 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08116,980,501 - 116,993,182 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08116,334,176 - 116,346,857 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,470,871 - 113,483,433 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18113,492,696 - 113,493,023 (-)NCBI
Celera8108,195,279 - 108,207,962 (-)NCBICelera
Cytogenetic Map8q32NCBI
Dag1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555321,397,900 - 1,466,312 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555321,446,553 - 1,465,310 (+)NCBIChiLan1.0ChiLan1.0
DAG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2039,708,053 - 39,778,550 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12039,707,672 - 39,779,094 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dag1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365291,099,510 - 1,171,587 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DAG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,029,329 - 32,092,453 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,028,019 - 32,092,450 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DAG1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,864,058 - 10,934,179 (+)NCBI
ChlSab1.1 Ensembl2210,865,724 - 10,934,200 (+)Ensembl
Dag1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247303,417,356 - 3,488,300 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000048237   ⟹   ENSPPAP00000025410
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl350,640,615 - 50,703,852 (+)Ensembl
RefSeq Acc Id: XM_003818856   ⟹   XP_003818904
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1350,638,847 - 50,703,852 (+)NCBI
Mhudiblu_PPA_v0349,397,619 - 49,464,689 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008972265   ⟹   XP_008970513
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1350,640,615 - 50,703,852 (+)NCBI
Mhudiblu_PPA_v0349,398,246 - 49,464,689 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008972266   ⟹   XP_008970514
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1350,637,707 - 50,703,852 (+)NCBI
Mhudiblu_PPA_v0349,396,180 - 49,464,689 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034956459   ⟹   XP_034812350
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0349,397,645 - 49,464,688 (+)NCBI
RefSeq Acc Id: XM_034956460   ⟹   XP_034812351
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0349,397,619 - 49,464,689 (+)NCBI
RefSeq Acc Id: XM_034956461   ⟹   XP_034812352
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0349,397,619 - 49,464,689 (+)NCBI
RefSeq Acc Id: XM_034956462   ⟹   XP_034812353
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0349,397,619 - 49,464,689 (+)NCBI
RefSeq Acc Id: XM_034956463   ⟹   XP_034812354
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0349,397,619 - 49,464,689 (+)NCBI
RefSeq Acc Id: XM_034956464   ⟹   XP_034812355
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0349,397,763 - 49,464,689 (+)NCBI
RefSeq Acc Id: XM_034956465   ⟹   XP_034812356
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0349,397,763 - 49,464,689 (+)NCBI
RefSeq Acc Id: XM_034956467   ⟹   XP_034812358
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0349,397,763 - 49,464,689 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_008970514   ⟸   XM_008972266
- Sequence:
RefSeq Acc Id: XP_003818904   ⟸   XM_003818856
- Sequence:
RefSeq Acc Id: XP_008970513   ⟸   XM_008972265
- Sequence:
RefSeq Acc Id: XP_034812354   ⟸   XM_034956463
RefSeq Acc Id: XP_034812351   ⟸   XM_034956460
RefSeq Acc Id: XP_034812353   ⟸   XM_034956462
RefSeq Acc Id: XP_034812352   ⟸   XM_034956461
RefSeq Acc Id: XP_034812350   ⟸   XM_034956459
RefSeq Acc Id: XP_034812355   ⟸   XM_034956464
RefSeq Acc Id: XP_034812356   ⟸   XM_034956465
RefSeq Acc Id: XP_034812358   ⟸   XM_034956467
RefSeq Acc Id: ENSPPAP00000025410   ⟸   ENSPPAT00000048237
Protein Domains
Peptidase S72


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035837 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000025410 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000048237 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.30.70.1040 UniProtKB/TrEMBL
InterPro Alpha-dystroglycan_domain_2 UniProtKB/TrEMBL
  Alpha_DG1_N2 UniProtKB/TrEMBL
  Cadg UniProtKB/TrEMBL
  Cadherin-like UniProtKB/TrEMBL
  DAG1 UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  SEA_DG_dom UniProtKB/TrEMBL
KEGG Report pps:100987680 UniProtKB/TrEMBL
NCBI Gene DAG1 ENTREZGENE
Pfam a_DG1_N2 UniProtKB/TrEMBL
  DAG1 UniProtKB/TrEMBL
PROSITE SEA_DG UniProtKB/TrEMBL
SMART CADG UniProtKB/TrEMBL
Superfamily-SCOP SSF111006 UniProtKB/TrEMBL
  SSF49313 UniProtKB/TrEMBL
UniProt A0A2R9BAV6_PANPA UniProtKB/TrEMBL