ABCC8 (ATP binding cassette subfamily C member 8) - Rat Genome Database

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Gene: ABCC8 (ATP binding cassette subfamily C member 8) Pan paniscus
Analyze
Symbol: ABCC8
Name: ATP binding cassette subfamily C member 8
RGD ID: 11993162
Description: ENCODES a protein that exhibits ATPase-coupled cation transmembrane transporter activity (ortholog); potassium channel activity (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN cellular glucose homeostasis (ortholog); cellular response to organic substance (ortholog); female pregnancy (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; altered insulin secretion pathway; ASSOCIATED WITH atrial heart septal defect (ortholog); brain edema (ortholog); Brain Injuries (ortholog); FOUND IN inward rectifying potassium channel (ortholog); mitochondrion (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: ATP-binding cassette sub-family C member 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11117,133,063 - 17,216,870 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1117,133,063 - 17,216,870 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01117,447,564 - 17,531,513 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway  (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
altered insulin secretion pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
diabetes mellitus pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
forkhead class A signaling pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
gliclazide pharmacodynamics pathway  (ISO)
glyburide pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
insulin secretion pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
potassium channel inhibitors pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
type 2 diabetes mellitus pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

Genomics

Comparative Map Data
ABCC8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11117,133,063 - 17,216,870 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1117,133,063 - 17,216,870 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01117,447,564 - 17,531,513 (-)NCBIMhudiblu_PPA_v0panPan3
ABCC8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1117,392,498 - 17,476,894 (-)EnsemblGRCh38hg38GRCh38
GRCh381117,392,498 - 17,476,849 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371117,414,045 - 17,498,392 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361117,371,008 - 17,455,025 (-)NCBINCBI36hg18NCBI36
Build 341117,371,008 - 17,455,025NCBI
Celera1117,544,259 - 17,628,301 (-)NCBI
Cytogenetic Map11p15.1NCBI
HuRef1117,098,250 - 17,182,251 (-)NCBIHuRef
CHM1_11117,414,230 - 17,498,274 (-)NCBICHM1_1
Abcc8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,753,947 - 45,829,457 (-)NCBIGRCm39mm39
GRCm39 Ensembl745,753,947 - 45,829,457 (-)Ensembl
GRCm38746,104,523 - 46,180,039 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl746,104,523 - 46,180,033 (-)EnsemblGRCm38mm10GRCm38
MGSCv37753,359,893 - 53,435,403 (-)NCBIGRCm37mm9NCBIm37
MGSCv36745,972,565 - 46,048,075 (-)NCBImm8
Celera741,577,813 - 41,653,419 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.66NCBI
Abcc8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2196,598,663 - 96,679,495 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl196,598,647 - 96,679,510 (-)Ensembl
Rnor_6.01102,110,708 - 102,191,287 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1102,110,708 - 102,191,287 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01103,194,473 - 103,275,508 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,622,574 - 96,703,723 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1196,700,590 - 96,781,880 (-)NCBI
Celera190,849,685 - 90,928,224 (-)NCBICelera
Cytogenetic Map1q22NCBI
Abcc8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541432,216,196 - 32,289,053 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541432,216,243 - 32,289,028 (-)NCBIChiLan1.0ChiLan1.0
ABCC8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12139,963,001 - 40,037,040 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2139,962,947 - 40,036,981 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2139,461,452 - 39,537,172 (-)NCBI
ROS_Cfam_1.02141,066,585 - 41,142,504 (-)NCBI
UMICH_Zoey_3.12140,079,280 - 40,154,977 (-)NCBI
UNSW_CanFamBas_1.02140,286,724 - 40,362,392 (-)NCBI
UU_Cfam_GSD_1.02140,625,433 - 40,701,220 (-)NCBI
Abcc8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494745,574,794 - 45,648,893 (+)NCBI
SpeTri2.0NW_0049365281,608,782 - 1,682,873 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCC8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl241,666,909 - 41,754,620 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1241,666,974 - 41,754,624 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2244,725,495 - 44,812,691 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABCC8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1147,494,861 - 47,578,818 (+)NCBI
ChlSab1.1 Ensembl147,494,959 - 47,578,882 (+)Ensembl
Vero_WHO_p1.0NW_023666038144,915,676 - 145,009,083 (+)NCBI
Abcc8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247669,018,616 - 9,092,365 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000029671   ⟹   ENSPPAP00000007373
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1117,133,063 - 17,216,870 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029675   ⟹   ENSPPAP00000007374
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1117,133,169 - 17,216,837 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029676   ⟹   ENSPPAP00000007375
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1117,133,169 - 17,138,114 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029679   ⟹   ENSPPAP00000007378
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1117,147,075 - 17,216,837 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029680   ⟹   ENSPPAP00000007379
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1117,210,275 - 17,216,837 (-)Ensembl
RefSeq Acc Id: XM_003818212   ⟹   XP_003818260
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11117,133,063 - 17,216,870 (-)NCBI
Mhudiblu_PPA_v01117,447,564 - 17,531,511 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008971484   ⟹   XP_008969732
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11117,133,063 - 17,216,870 (-)NCBI
Mhudiblu_PPA_v01117,447,564 - 17,531,511 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024930811   ⟹   XP_024786579
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11117,133,063 - 17,216,870 (-)NCBI
Mhudiblu_PPA_v01117,447,564 - 17,531,511 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024930812   ⟹   XP_024786580
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11117,133,063 - 17,216,870 (-)NCBI
Mhudiblu_PPA_v01117,447,564 - 17,531,510 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034932230   ⟹   XP_034788121
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01117,447,564 - 17,531,511 (-)NCBI
RefSeq Acc Id: XM_034932231   ⟹   XP_034788122
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01117,447,670 - 17,531,511 (-)NCBI
RefSeq Acc Id: XM_034932232   ⟹   XP_034788123
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01117,447,564 - 17,531,511 (-)NCBI
RefSeq Acc Id: XM_034932234   ⟹   XP_034788125
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01117,448,947 - 17,531,513 (-)NCBI
RefSeq Acc Id: XR_004665018
RefSeq Status:
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01117,447,729 - 17,531,512 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_003818260   ⟸   XM_003818212
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008969732   ⟸   XM_008971484
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_024786580   ⟸   XM_024930812
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_024786579   ⟸   XM_024930811
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_034788123   ⟸   XM_034932232
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034788121   ⟸   XM_034932230
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034788122   ⟸   XM_034932231
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034788125   ⟸   XM_034932234
- Peptide Label: isoform X8
RefSeq Acc Id: ENSPPAP00000007379   ⟸   ENSPPAT00000029680
RefSeq Acc Id: ENSPPAP00000007374   ⟸   ENSPPAT00000029675
RefSeq Acc Id: ENSPPAP00000007375   ⟸   ENSPPAT00000029676
RefSeq Acc Id: ENSPPAP00000007378   ⟸   ENSPPAT00000029679
RefSeq Acc Id: ENSPPAP00000007373   ⟸   ENSPPAT00000029671


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000026555 Ensembl, ENTREZGENE
Ensembl Protein ENSPPAP00000007373 ENTREZGENE
  ENSPPAP00000007374 ENTREZGENE
NCBI Gene ABCC8 ENTREZGENE