NGB (neuroglobin) - Rat Genome Database

Name: NGB
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: NGB (neuroglobin) Pan paniscus

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Symbol:

NGB

Name:

neuroglobin

RGD ID:

11757206

Description:

ENCODES a protein that exhibits GDP-dissociation inhibitor activity (inferred); heme binding (inferred); metal ion binding (inferred); INVOLVED IN cellular response to hydrogen peroxide (ortholog); negative regulation of apoptotic process (ortholog); neuron projection development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Injuries (ortholog); encephalitis (ortholog); FOUND IN cytosol (ortholog); mitochondrial matrix (ortholog); perikaryon (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NGB (neuroglobin)	NCBI	Ortholog
Mus musculus (house mouse):	Ngb (neuroglobin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ngb (neuroglobin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ngb (neuroglobin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NGB (neuroglobin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ngb (neuroglobin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NGB (neuroglobin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NGB (neuroglobin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ngb (neuroglobin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	78,349,121 - 78,354,740 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	77,565,625 - 77,571,242 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	57,818,491 - 57,824,196 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	77,020,274 - 77,025,983 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	77,020,274 - 77,025,983 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

Brain Injuries (ISO)

encephalitis (ISO)

Nervous System Heredodegenerative Disorders (ISO)

retinal ischemia (ISO)

Sleep Deprivation (ISO)

Subarachnoid Hemorrhage (ISO)

transient cerebral ischemia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to hydrogen peroxide (ISO)

cellular response to hypoxia (IEA)

negative regulation of apoptotic process (ISO)

neuron projection development (ISO)

oxygen transport (IEA,ISO)

positive regulation of catalytic activity (ISO)

response to hypoxia (ISO)

response to iron ion (ISO)

Cellular Component

cytosol (ISO)

mitochondrial matrix (ISO)

perikaryon (ISO)

Molecular Function

GDP-dissociation inhibitor activity (IEA)

heme binding (IEA)

metal ion binding (IEA)

nitrite reductase activity (IEA)

oxygen binding (IEA)

oxygen carrier activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

NGB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	78,349,121 - 78,354,740 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	77,565,625 - 77,571,242 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	57,818,491 - 57,824,196 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	77,020,274 - 77,025,983 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	77,020,274 - 77,025,983 (-)	Ensembl	panpan1.1		panPan2

NGB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	77,265,483 - 77,271,206 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	77,265,483 - 77,271,206 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	77,731,826 - 77,737,549 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	76,801,587 - 76,807,408 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	76,801,580 - 76,807,408	NCBI
Celera	14	57,770,473 - 57,776,215 (-)	NCBI		Celera
Cytogenetic Map	14	q24.3	NCBI
HuRef	14	57,898,325 - 57,904,062 (-)	NCBI		HuRef
CHM1_1	14	77,671,361 - 77,677,104 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	71,474,790 - 71,480,551 (-)	NCBI		T2T-CHM13v2.0

Ngb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	87,144,305 - 87,149,313 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	87,144,305 - 87,149,313 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	87,097,531 - 87,102,539 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	87,097,531 - 87,102,539 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	88,438,481 - 88,443,489 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	87,986,634 - 87,991,642 (-)	NCBI		MGSCv36	mm8
Celera	12	88,562,002 - 88,567,162 (-)	NCBI		Celera
Cytogenetic Map	12	D2	NCBI
cM Map	12	41.29	NCBI

Ngb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	112,475,332 - 112,480,786 (-)	NCBI		GRCr8
mRatBN7.2	6	106,744,378 - 106,749,830 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	106,744,378 - 106,749,830 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	106,912,130 - 106,917,574 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	107,210,967 - 107,216,411 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	106,580,643 - 106,586,085 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	111,126,259 - 111,131,699 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	111,126,261 - 111,132,320 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	120,412,241 - 120,417,508 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	111,231,188 - 111,236,255 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	111,234,718 - 111,239,786 (-)	NCBI
Celera	6	104,565,839 - 104,571,131 (-)	NCBI		Celera
Cytogenetic Map	6	q31	NCBI

Ngb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	1,170,888 - 1,175,978 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	1,170,888 - 1,175,978 (-)	NCBI	ChiLan1.0	ChiLan1.0

NGB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	50,081,960 - 50,086,071 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	50,081,960 - 50,085,435 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	49,769,803 - 49,773,792 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	50,314,590 - 50,325,270 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	50,315,118 - 50,319,630 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	49,978,294 - 49,982,287 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	50,001,322 - 50,005,311 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	50,399,520 - 50,403,524 (-)	NCBI		UU_Cfam_GSD_1.0

Ngb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	25,969,328 - 25,974,879 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936488	6,095,016 - 6,098,543 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936488	6,094,089 - 6,098,876 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NGB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	100,340,940 - 100,346,438 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	100,341,974 - 100,346,263 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	106,610,972 - 106,615,261 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NGB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	54,510,877 - 54,518,535 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	54,511,924 - 54,516,210 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	42,711,096 - 42,716,772 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ngb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	24,640,181 - 24,647,243 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	24,640,389 - 24,645,041 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003808864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000058308 ⟹ ENSPPAP00000035420

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	14	77,020,274 - 77,025,983 (-)	Ensembl

RefSeq Acc Id:

XM_003808864 ⟹ XP_003808912

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	15	78,349,121 - 78,354,740 (-)	NCBI
NHGRI_mPanPan1	14	77,565,625 - 77,571,242 (-)	NCBI
Mhudiblu_PPA_v0	14	57,818,491 - 57,824,196 (-)	NCBI
PanPan1.1	14	77,020,274 - 77,025,983 (-)	NCBI

Sequence:

show sequence

TTCCCAGGCCACCATAGCGGCTGGCGGAGGGAGCGCGCGCCTTGCTGGCCTGGGAGGGGGGCGG
GGGGGCGTGGCGGCTTTAAAGCGCCCAGCCCAGGCGTCGCGGGGTGGGGCGGCTCTGGCGGCTG
CGGGGCGCGGGGCGCAGGGCGTAGCGGCCAAGCGGGGTCCCCGGAAGCACAGCTGGGGGTGTCT
CCACCTACGACTGGCCGCGCGTCTTTTCTCTCCCGCGCCAGGGAAGGAGCGGCTGCGGCCCCCG
CCAGGCGGAGGCACGGGGGGCGTACGAGGGGCGGAGGGGACCGCGTCGCGGAGGAGATGGCGCG
GCACGTGCGGTGACGGCACCCGAGCCCTGAGGGTCCCAGCCCCGCGCTCCGCGTCCCCGGGACA
GCATGGAGCGCCCGGAGCCCGAGCTGATCCGGCAGAGCTGGCGGGCAGTGAGCCGCAGCCCGCT
GGAGCACGGCACCGTCCTGTTTGCCAGGCTGTTTGCCCTGGAGCCTGACCTGCTGCCCCTCTTC
CAGTACAACTGCCGCCAGTTCTCCAGCCCAGAGGACTGTCTCTCCTCGCCTGAGTTCCTGGACC
ACATCAGGAAGGTGATGCTCGTGATTGATGCTGCAGTGACCAATGTGGAAGACCTGTCCTCACT
GGAGGAGTACCTTGCCAGCCTGGGTAGGAAGCACCGGGCAGTGGGTGTGAAGCTCAGCTCCTTC
TCGACAGTGGGTGAGTCTCTGCTCTACATGCTGGAGAAGTGTCTGGGCCCTGCCTTCACACCAG
CCACACGGGCTGCCTGGAGCCAACTCTACGGGGCCGTAGTGCAGGCCATGAGTCGAGGCTGGGA
TGGCGAGTAAGAGGCGACCCCGCCCGGCAGCCCCCATCCATCTGTGTCTGTCTGTTGGCCTGTA
TCTGTTGTAGCCCAGGCTCCCCAAGCTTCCCTGCATCTTGGTCCTTGTCCCCTTGGCCACACTG
GAGAGGTGATGGGGCAGGGCTGGGTCTCAGTATCCCAGAGTCCAGCTGCAGAAGGAGTGGCTTT
TCCTCCAGGAAGGGGCTTCTGGGTGTCCCCTCATCCCCAGTAGCCTCTTTCTTGCCTTTCTTTT
TACCTTTTTGGCACTCCCTCTGACCCCGCGATGAGTGTTTTGGTGGTAGAGGTGGGATGAGCTG
GAAAGGTATGGAGGTGGGAGAGGATGGGGCTCTTCTGTCTGTCCTGCTTCTTCAGGTGAGTGCA
GGCCAAGGCGGGGGTGAGATGGCTGAGCTTCCAGCCCCTTCTATCCTGCCTGCCCAGTCCCTTC
ACTGCTTTCCTGCCCCAAGATGGCTTGCTTTTCTCAAATAAGAGAAAGAGCAGCTTTAGCCTTC
TTGGTGGAATCCCAGGCAGTGGGAGCAGAATCAGAACTGCCAGGGAAGGGAAGGGGGACCTGGG
TCTCAATGGGTCTCATCTGAGTCTCGCGGGCTGTGCAGATGCCCTGACAGAGTCAGTTTCCTTT
GGCGGCATTCCCTTTCCCTCATTCAGCACTTCTGCTGGGAACTCCCTGACTATTCCGCTGCTGC
AGGAACCCAGCTAGCTGGCCAGGTGGGGAGGGGCTGGGGACCGGCCAGGAAGGAGGGGTGACTT
CATCCCAGAGAGACCCAAGTTCCCCCAGCCCTTCATCACCAACCCGCTCCTGCAGGAGTGAGTC
TTAACCTCCCCTGGCCCTCCTTTGTGGCTCAGCCTGCAGCGACTGTGAGGCCACAGCTCCTCAG
ATTCACTGCCCGCTGTGTGCCAGTACTCAGGCAGCTGGAGAGAAGAGAAGGCAGCCGCAGAGGC
CCCCGCCCTCACCCCAGCCATCTGCACTTTTACCGTTTGCTCTATGCTGACTGTGGTCCTATAA
ACTCATGAGAAATAAACTGGTTCTGTGTGCCTCTCTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003808912	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000035420
	ENSPPAP00000035420.1

RefSeq Acc Id:	XP_003808912 ⟸ XM_003808864
- UniProtKB:	A0A2R9C3L3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MERPEPELIRQSWRAVSRSPLEHGTVLFARLFALEPDLLPLFQYNCRQFSSPEDCLSSPEFLDH IRKVMLVIDAAVTNVEDLSSLEEYLASLGRKHRAVGVKLSSFSTVGESLLYMLEKCLGPAFTPA TRAAWSQLYGAVVQAMSRGWDGE hide sequence

Ensembl Acc Id:

ENSPPAP00000035420 ⟸ ENSPPAT00000058308

Protein Domains

GLOBIN

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000040520	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000058308.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.490.10	UniProtKB/TrEMBL
InterPro	Globin	UniProtKB/TrEMBL
	Globin-like_OT	UniProtKB/TrEMBL
	Globin-like_sf	UniProtKB/TrEMBL
	Globin/Proto	UniProtKB/TrEMBL
KEGG Report	pps:100991110	UniProtKB/TrEMBL
NCBI Gene	NGB	ENTREZGENE
PANTHER	BLR2807 PROTEIN	UniProtKB/TrEMBL
	NEUROGLOBIN	UniProtKB/TrEMBL
Pfam	Globin	UniProtKB/TrEMBL
PROSITE	GLOBIN	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46458	UniProtKB/TrEMBL
UniProt	A0A2R9C3L3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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