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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of signaling receptor activity
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Accession:GO:2000273 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of signaling receptor activity.
Synonyms:exact_synonym: positive regulation of signalling receptor activity


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positive regulation of signaling receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 involved_in ISO (PMID:29020624) RGD PMID:29020624 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Edn1 endothelin 1 acts_upstream_of ISO (PMID:17178876) RGD PMID:17178876 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (MGI:4845816|PMID:20660291) RGD PMID:20660291 MGI:4845816 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Hdac1 histone deacetylase 1 acts_upstream_of ISO (PMID:18316616) RGD PMID:18316616 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of ISO (PMID:18316616) RGD PMID:18316616 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hdac6 histone deacetylase 6 acts_upstream_of ISO (PMID:15916966), (PMID:18316616) RGD PMID:15916966 PMID:18316616 NCBI chr  X:15,396,185...15,417,486
Ensembl chr  X:15,295,473...15,316,671
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Hfe homeostatic iron regulator involved_in ISO UniProtKB:P02787|UniProtKB:P61769|UniProtKB:Q07891|UniProtKB:Q9UP52 (PMID:18353247) RGD PMID:18353247 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of
involved_in
ISO
IEA
(PMID:17178876)
GO_REF:0000107
RGD
Ensembl
PMID:17178876 GO_REF:0000107 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Ifng interferon gamma involved_in ISO UniProtKB:P05067|UniProtKB:P49768 (MGI:5776417|PMID:26227742) RGD PMID:26227742 MGI:5776417 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 acts_upstream_of_or_within ISO (PMID:10443688) RGD PMID:10443688 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Itgb1 integrin subunit beta 1 involved_in ISO
IEA
(PMID:24044949)
GO_REF:0000107
RGD
Ensembl
PMID:24044949 GO_REF:0000107 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Jak2 Janus kinase 2 involved_in ISO UniProtKB:P01580 (MGI:5776417|PMID:26227742) RGD PMID:26227742 MGI:5776417 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
positive regulation of AMPA receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb2 adrenoceptor beta 2 involved_in ISO
IEA
ComplexPortal:CPX-1070 (PMID:20395454)
GO_REF:0000107
RGD
Ensembl
PMID:20395454 GO_REF:0000107 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein involved_in IBA
IMP
PMID:21873635
PMID:17088211
GO_Central
CACAO
PMID:21873635, PMID:17088211 RGD:13792537, RGD:10047209 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 IDA RGD PMID:16093395 RGD:13515081 NCBI chr 7:119,228,112...119,353,332
Ensembl chr 7:119,228,102...119,352,605
JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 IDA RGD PMID:12771129 RGD:13515082 NCBI chr 1:192,613,766...192,708,371
Ensembl chr 1:192,613,372...192,709,078
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 IDA RGD PMID:12771129 RGD:13515082 NCBI chr10:95,954,160...96,015,484
Ensembl chr10:95,951,234...96,015,499
JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 IDA RGD PMID:12771129 RGD:13515082 NCBI chr 1:64,330,106...64,350,338
Ensembl chr 1:64,330,106...64,350,338
JBrowse link
G Nlgn3 neuroligin 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5320268|PMID:21642956)
BHF-UCL
RGD
PMID:21642956 GO_REF:0000024 MGI:5320268 NCBI chr  X:71,199,390...71,227,460
Ensembl chr  X:71,199,491...71,222,732
JBrowse link
G Reln reelin involved_in IEA
ISO
GO_REF:0000107
(MGI:3765383|PMID:17229826)
Ensembl
RGD
PMID:17229826 GO_REF:0000107 MGI:3765383 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:4948759|PMID:21423165)
GO_REF:0000024
Ensembl
RGD
BHF-UCL
PMID:21423165 GO_REF:0000024 GO_REF:0000107 MGI:4948759 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link
positive regulation of androgen receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bud31 BUD31 homolog involved_in ISS
ISO
GO_REF:0000024
(PMID:25091737)
UniProt
RGD
PMID:25091737 GO_REF:0000024 NCBI chr12:11,232,963...11,240,449
Ensembl chr12:11,232,964...11,240,400
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:17510388)
ParkinsonsUK-UCL
Ensembl
RGD
PMID:17510388 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Rwdd1 RWD domain containing 1 involved_in ISO (MGI:5882884|PMID:18761815) RGD PMID:18761815 MGI:5882884 NCBI chr20:27,534,361...27,552,225
Ensembl chr20:27,535,324...27,552,349
JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:20181722) RGD PMID:20181722 NCBI chr  X:71,412,291...71,486,456
Ensembl chr  X:71,412,289...71,485,085
JBrowse link
positive regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO
IEA
(PMID:17655843), (PMID:18483258)
GO_REF:0000107
RGD
Ensembl
PMID:17655843 PMID:18483258 GO_REF:0000107 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adora1 adenosine A1 receptor IMP RGD PMID:19574994 RGD:2317913 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:17655843) RGD PMID:17655843 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Areg amphiregulin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Btc betacellulin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:18,231,854...18,270,621
Ensembl chr14:18,231,860...18,272,484
JBrowse link
G Egf epidermal growth factor involved_in ISO (PMID:15611079), (PMID:20353436), (PMID:22732145) RGD PMID:15611079 PMID:20353436 PMID:22732145 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Epgn epithelial mitogen involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:1934957|PMID:11278323)
PMID:21873635
(PMID:15611079)
HGNC-UCL
RGD
PMID:11278323 PMID:15611079, PMID:21873635 GO_REF:0000024 MGI:1934957, RGD:13792537 NCBI chr14:18,627,103...18,635,135
Ensembl chr14:18,626,644...18,634,309
JBrowse link
G Ereg epiregulin involved_in IBA
IDA
PMID:21873635
PMID:9990076
GO_Central
UniProt
PMID:21873635, PMID:9990076 RGD:13792537, RGD:632743 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr 2:184,230,191...184,309,805
Ensembl chr 2:184,231,260...184,309,664
JBrowse link
G Hbegf heparin-binding EGF-like growth factor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 involved_in ISO (PMID:26514923) RGD PMID:26514923 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Neurl1 neuralized E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:2152037 (MGI:2149168|PMID:11481456) RGD PMID:11481456 MGI:2149168 NCBI chr 1:266,953,006...267,038,879
Ensembl chr 1:266,952,561...267,038,883
JBrowse link
G Tgfa transforming growth factor alpha involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:11278323)
HGNC-UCL
RGD
PMID:11278323, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
positive regulation of NMDA glutamate receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 involved_in IGI PMID:27094552 ARUK-UCL PMID:27094552 RGD:14397550 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in IGI PMID:27094552 ARUK-UCL PMID:27094552 RGD:14397550
G Cfl1 cofilin 1 IMP RGD PMID:24089484 RGD:11570552 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Ephb2 Eph receptor B2 involved_in ISO (MGI:4867584|PMID:21113149) RGD PMID:21113149 MGI:4867584 NCBI chr 5:155,024,478...155,143,539
Ensembl chr 5:155,022,493...155,204,456
JBrowse link
G Ifng interferon gamma involved_in IGI PMID:27094552 ARUK-UCL PMID:27094552 RGD:14397550 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr1 interferon gamma receptor 1 involved_in IGI PMID:27094552 ARUK-UCL PMID:27094552 RGD:14397550 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Ifngr2 interferon gamma receptor 2 involved_in IGI PMID:27094552 ARUK-UCL PMID:27094552 RGD:14397550 NCBI chr11:31,694,339...31,712,611
Ensembl chr11:31,694,339...31,712,611
JBrowse link
G Pink1 PTEN induced kinase 1 IMP RGD PMID:20698836 RGD:13463453 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Rgs9 regulator of G-protein signaling 9 IDA RGD PMID:16510730 RGD:1599994 NCBI chr10:97,509,971...97,582,188
Ensembl chr10:97,509,971...97,582,188
JBrowse link
receptor transactivation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in IMP
IEA
ISO
GO_REF:0000107
(PMID:17655843)
Ensembl
RGD
PMID:17655843, PMID:25232008 GO_REF:0000107, RGD:13703036 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:17215105), (PMID:17655843) RGD PMID:17215105 PMID:17655843 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Adra2b adrenoceptor alpha 2B involved_in ISO (PMID:17215105) RGD PMID:17215105 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987
JBrowse link
G Adra2c adrenoceptor alpha 2C involved_in ISO (PMID:17215105) RGD PMID:17215105 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of molecular function 3070
        regulation of signaling receptor activity 170
          positive regulation of signaling receptor activity 48
            positive regulation of AMPA receptor activity 9
            positive regulation of G protein-coupled receptor activity in other organism 0
            positive regulation of GABA-A receptor activity 0
            positive regulation of NMDA glutamate receptor activity 9
            positive regulation of advanced glycation end-product receptor activity 0
            positive regulation of androgen receptor activity 4
            positive regulation of beta1-adrenergic receptor activity 0
            positive regulation of brain-derived neurotrophic factor-activated receptor activity 0
            positive regulation of chemorepellent activity 0
            positive regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway 0
            positive regulation of corticotropin-releasing hormone receptor activity 0
            positive regulation of cytokine activity 0
            positive regulation of epidermal growth factor-activated receptor activity 13
            positive regulation of growth hormone activity 0
            positive regulation of nerve growth factor receptor activity 0
            positive regulation of osmolarity-sensing cation channel activity 0
            positive regulation of proteinase activated receptor activity 0
            receptor transactivation 4
Path 2
Term Annotations click to browse term
  biological_process 19491
    biological regulation 13515
      regulation of biological process 12773
        regulation of cellular process 12275
          signal transduction 6881
            regulation of signal transduction 2960
              regulation of signaling receptor activity 170
                positive regulation of signaling receptor activity 48
                  positive regulation of AMPA receptor activity 9
                  positive regulation of G protein-coupled receptor activity in other organism 0
                  positive regulation of GABA-A receptor activity 0
                  positive regulation of NMDA glutamate receptor activity 9
                  positive regulation of advanced glycation end-product receptor activity 0
                  positive regulation of androgen receptor activity 4
                  positive regulation of beta1-adrenergic receptor activity 0
                  positive regulation of brain-derived neurotrophic factor-activated receptor activity 0
                  positive regulation of chemorepellent activity 0
                  positive regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway 0
                  positive regulation of corticotropin-releasing hormone receptor activity 0
                  positive regulation of cytokine activity 0
                  positive regulation of epidermal growth factor-activated receptor activity 13
                  positive regulation of growth hormone activity 0
                  positive regulation of nerve growth factor receptor activity 0
                  positive regulation of osmolarity-sensing cation channel activity 0
                  positive regulation of proteinase activated receptor activity 0
                  receptor transactivation 4
paths to the root