FABP1 (fatty acid binding protein 1) - Rat Genome Database

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Gene: FABP1 (fatty acid binding protein 1) Pan paniscus
Analyze
Symbol: FABP1
Name: fatty acid binding protein 1
RGD ID: 11672548
Description: ENCODES a protein that exhibits bile acid binding (ortholog); binding (ortholog); fatty acid binding (ortholog); INVOLVED IN arachidonate metabolic process (ortholog); cell population proliferation (ortholog); cholesterol metabolic process (ortholog); ASSOCIATED WITH acute kidney tubular necrosis (ortholog); Acute Liver Failure (ortholog); end stage renal disease (ortholog); FOUND IN apical cortex (ortholog); peroxisomal matrix (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fatty acid-binding protein, liver
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21239,132,205 - 39,179,712 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A39,134,991 - 39,182,472 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A87,256,032 - 87,303,505 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A89,165,308 - 89,170,448 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A89,165,315 - 89,170,448 (-)EnsemblpanPan2panpan1.1
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
arachidonate metabolic process  (ISO)
cell population proliferation  (ISO)
cellular detoxification  (IEA)
cellular oxidant detoxification  (IEA)
cellular response to hydrogen peroxide  (IEA)
cellular response to hypoxia  (IEA)
cholesterol metabolic process  (ISO)
connective tissue replacement  (ISO)
D-glucose transmembrane transport  (ISO)
digestive system process  (ISO)
digestive tract development  (ISO)
endocannabinoid signaling pathway  (ISO)
fatty acid biosynthetic process  (ISO)
fatty acid metabolic process  (ISO)
fatty acid oxidation  (ISO)
fatty acid transport  (IEA,ISO)
gene expression  (ISO)
glucose metabolic process  (ISO)
glutamine metabolic process  (ISO)
glycerol metabolic process  (ISO)
glycolytic process  (ISO)
hepatic stellate cell activation  (ISO)
inflammatory response  (ISO)
intestinal absorption  (ISO)
ketone body metabolic process  (ISO)
lipid metabolic process  (ISO)
lipoprotein metabolic process  (ISO)
lipoprotein transport  (ISO)
liver development  (ISO)
long-chain fatty acid transport  (ISO)
multicellular organism growth  (ISO)
phospholipid metabolic process  (ISO)
positive regulation of fatty acid beta-oxidation  (ISO)
positive regulation of hydrolase activity  (ISO)
renal protein absorption  (ISO)
response to food  (ISO)
response to paracetamol  (ISO)
response to tetrachloromethane  (ISO)
response to vitamin B3  (ISO)
response to wounding  (ISO)
response to xenobiotic stimulus  (ISO)
retinol metabolic process  (ISO)
smooth muscle tissue development  (ISO)
triglyceride metabolic process  (ISO)
unsaturated fatty acid biosynthetic process  (ISO)
very-low-density lipoprotein particle clearance  (ISO)
xenobiotic transport  (ISO)

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FABP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21239,132,205 - 39,179,712 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A39,134,991 - 39,182,472 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A87,256,032 - 87,303,505 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A89,165,308 - 89,170,448 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A89,165,315 - 89,170,448 (-)EnsemblpanPan2panpan1.1
FABP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38288,122,982 - 88,128,062 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl288,122,982 - 88,128,062 (-)Ensemblhg38GRCh38
GRCh37288,422,501 - 88,427,581 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36288,203,625 - 88,208,693 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34288,261,771 - 88,266,840NCBI
Celera288,358,422 - 88,363,490 (+)NCBICelera
Cytogenetic Map2p11.2NCBI
HuRef287,344,752 - 87,349,901 (-)NCBIHuRef
CHM1_1288,351,787 - 88,356,936 (-)NCBICHM1_1
T2T-CHM13v2.0288,134,227 - 88,181,784 (-)NCBIT2T-CHM13v2.0
Fabp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39671,176,863 - 71,182,018 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl671,176,811 - 71,182,007 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38671,199,879 - 71,205,034 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl671,199,827 - 71,205,023 (+)Ensemblmm10GRCm38
MGSCv37671,149,882 - 71,155,017 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36671,129,467 - 71,134,602 (+)NCBIMGSCv36mm8
Celera673,279,169 - 73,284,304 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.14NCBI
Fabp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84104,744,302 - 104,753,119 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4104,744,309 - 104,753,113 (+)EnsemblGRCr8
mRatBN7.24103,191,015 - 103,194,791 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4103,191,006 - 103,194,788 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4108,579,494 - 108,583,270 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04104,354,593 - 104,358,369 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04102,960,918 - 102,964,694 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0499,063,181 - 99,066,957 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl499,063,181 - 99,066,954 (+)Ensemblrn6Rnor6.0
Rnor_5.04163,840,329 - 163,844,105 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44104,412,200 - 104,415,981 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera492,366,948 - 92,370,724 (+)NCBICelera
RGSC_v3.14104,656,680 - 104,660,462 (+)NCBI
Cytogenetic Map4q32NCBI
FABP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11738,242,119 - 38,247,969 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1738,242,119 - 38,247,962 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1737,927,199 - 37,933,049 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01738,974,817 - 38,980,672 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1738,974,817 - 38,980,665 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11738,141,305 - 38,147,138 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01738,177,707 - 38,183,562 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01738,525,592 - 38,531,443 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fabp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629280,115,372 - 80,120,099 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936712738,348 - 743,955 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936712738,361 - 743,073 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FABP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl357,850,499 - 57,854,956 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1357,850,511 - 57,854,966 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2360,622,675 - 60,627,082 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FABP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11418,660,058 - 18,666,730 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1418,659,836 - 18,667,127 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660801,109,470 - 1,116,478 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000047577   ⟹   ENSPPAP00000024752
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A89,165,315 - 89,170,448 (-)Ensembl
RefSeq Acc Id: XM_003805854   ⟹   XP_003805902
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,132,238 - 39,179,703 (+)NCBI
NHGRI_mPanPan12A39,134,998 - 39,182,472 (+)NCBI
Mhudiblu_PPA_v02A87,256,032 - 87,261,187 (-)NCBI
PanPan1.12A89,165,308 - 89,170,448 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034953515   ⟹   XP_034809406
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,132,231 - 39,179,703 (+)NCBI
NHGRI_mPanPan12A39,134,991 - 39,182,463 (+)NCBI
Mhudiblu_PPA_v02A87,256,032 - 87,303,505 (-)NCBI
RefSeq Acc Id: XM_063594583   ⟹   XP_063450653
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21239,132,205 - 39,179,712 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003805902 (Get FASTA)   NCBI Sequence Viewer  
  XP_034809406 (Get FASTA)   NCBI Sequence Viewer  
  XP_063450653 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024752.1
  ENSPPAP00050025382
RefSeq Acc Id: XP_003805902   ⟸   XM_003805854
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B589 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034809406   ⟸   XM_034953515
- Peptide Label: isoform X2
Ensembl Acc Id: ENSPPAP00000024752   ⟸   ENSPPAT00000047577
RefSeq Acc Id: XP_063450653   ⟸   XM_063594583
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B589 (UniProtKB/TrEMBL)
Protein Domains
Cytosolic fatty-acid binding proteins


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035506 Ensembl, UniProtKB/TrEMBL
  ENSPPAG00050018840 ENTREZGENE
Ensembl Transcript ENSPPAT00000047577.1 UniProtKB/TrEMBL
  ENSPPAT00050039744 ENTREZGENE
Gene3D-CATH 2.40.128.20 UniProtKB/TrEMBL
InterPro Calycin UniProtKB/TrEMBL
  Fatty_acid-bd UniProtKB/TrEMBL
  ILBP UniProtKB/TrEMBL
KEGG Report pps:100982892 UniProtKB/TrEMBL
NCBI Gene FABP1 ENTREZGENE
PANTHER PTHR11955 UniProtKB/TrEMBL
Pfam Lipocalin_7 UniProtKB/TrEMBL
PRINTS FATTYACIDBP UniProtKB/TrEMBL
PROSITE FABP UniProtKB/TrEMBL
Superfamily-SCOP SSF50814 UniProtKB/TrEMBL
UniProt A0A2R9B589 ENTREZGENE, UniProtKB/TrEMBL