ADNP (activity dependent neuroprotector homeobox) - Rat Genome Database

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Gene: ADNP (activity dependent neuroprotector homeobox) Pan paniscus
Analyze
Symbol: ADNP
Name: activity dependent neuroprotector homeobox
RGD ID: 11735866
Description: ENCODES a protein that exhibits beta-tubulin binding (ortholog); copper ion binding (ortholog); peptide binding (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cGMP-mediated signaling (ortholog); estrous cycle (ortholog); ASSOCIATED WITH Agenesis of Corpus Callosum (ortholog); Alzheimer's disease (ortholog); autism spectrum disorder (ortholog); FOUND IN axon (ortholog); dendrite (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22156,639,252 - 56,680,364 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12056,632,380 - 56,673,982 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02047,233,696 - 47,276,075 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12048,361,036 - 48,400,399 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2048,361,043 - 48,400,387 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ADNP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22156,639,252 - 56,680,364 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12056,632,380 - 56,673,982 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02047,233,696 - 47,276,075 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12048,361,036 - 48,400,399 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2048,361,043 - 48,400,387 (-)Ensemblpanpan1.1panPan2
ADNP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382050,888,918 - 50,931,437 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2050,888,916 - 50,931,437 (-)EnsemblGRCh38hg38GRCh38
GRCh372049,505,455 - 49,547,974 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362048,940,290 - 48,980,934 (-)NCBINCBI36Build 36hg18NCBI36
Build 342048,940,289 - 48,980,934NCBI
Celera2046,211,143 - 46,251,787 (-)NCBICelera
Cytogenetic Map20q13.13NCBI
HuRef2046,255,283 - 46,295,816 (-)NCBIHuRef
CHM1_12049,412,276 - 49,452,793 (-)NCBICHM1_1
T2T-CHM13v2.02052,659,514 - 52,702,036 (-)NCBIT2T-CHM13v2.0
Adnp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392168,022,885 - 168,049,032 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2168,022,906 - 168,049,032 (-)EnsemblGRCm39 Ensembl
GRCm382168,180,965 - 168,207,112 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2168,180,986 - 168,207,112 (-)EnsemblGRCm38mm10GRCm38
MGSCv372168,006,465 - 168,032,562 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362168,006,465 - 168,032,562 (-)NCBIMGSCv36mm8
Celera2174,124,697 - 174,151,114 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map288.41NCBI
Adnp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83177,310,258 - 177,340,379 (-)NCBIGRCr8
mRatBN7.23156,886,921 - 156,921,500 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3156,891,381 - 156,917,312 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3160,686,196 - 160,712,108 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03169,185,277 - 169,211,206 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03166,926,977 - 166,952,906 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03164,937,188 - 164,964,819 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3164,937,198 - 164,964,702 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03171,077,543 - 171,087,330 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43159,345,280 - 159,355,067 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13159,253,471 - 159,255,943 (-)NCBI
Celera3155,464,855 - 155,474,635 (-)NCBICelera
Cytogenetic Map3q42NCBI
Adnp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554457,492,257 - 7,531,862 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554457,498,223 - 7,530,828 (+)NCBIChiLan1.0ChiLan1.0
ADNP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12437,211,776 - 37,245,938 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2437,213,942 - 37,243,702 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2436,453,839 - 36,487,910 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02437,921,440 - 37,955,536 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2437,922,782 - 37,953,382 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12437,156,924 - 37,191,002 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02437,290,872 - 37,324,932 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02437,835,833 - 37,869,965 (-)NCBIUU_Cfam_GSD_1.0
Adnp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640188,401,492 - 188,429,717 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365143,855,672 - 3,885,718 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365143,855,113 - 3,883,036 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADNP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1752,317,913 - 52,332,079 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11752,316,388 - 52,350,732 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21758,757,490 - 58,790,779 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADNP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1213,037,446 - 13,080,287 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl213,039,866 - 13,081,161 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605061,470,166 - 61,513,443 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adnp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247904,832,494 - 4,854,845 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247904,822,467 - 4,854,852 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000047927   ⟹   ENSPPAP00000025101
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2048,361,043 - 48,400,387 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000047933   ⟹   ENSPPAP00000025107
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2048,361,806 - 48,375,949 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000047940   ⟹   ENSPPAP00000025114
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2048,362,313 - 48,375,944 (-)Ensembl
RefSeq Acc Id: XM_034947244   ⟹   XP_034803135
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22156,639,252 - 56,680,364 (-)NCBI
NHGRI_mPanPan12056,632,380 - 56,672,999 (-)NCBI
Mhudiblu_PPA_v02047,233,696 - 47,276,075 (-)NCBI
RefSeq Acc Id: XM_034947245   ⟹   XP_034803136
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22156,639,252 - 56,680,364 (-)NCBI
NHGRI_mPanPan12056,632,380 - 56,672,999 (-)NCBI
Mhudiblu_PPA_v02047,233,696 - 47,276,075 (-)NCBI
RefSeq Acc Id: XM_034947247   ⟹   XP_034803138
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22156,639,252 - 56,659,396 (-)NCBI
NHGRI_mPanPan12056,632,380 - 56,673,982 (-)NCBI
Mhudiblu_PPA_v02047,233,696 - 47,250,588 (-)NCBI
RefSeq Acc Id: XM_034947248   ⟹   XP_034803139
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22156,639,252 - 56,679,885 (-)NCBI
NHGRI_mPanPan12056,632,380 - 56,672,923 (-)NCBI
Mhudiblu_PPA_v02047,233,696 - 47,275,526 (-)NCBI
RefSeq Acc Id: XM_055104865   ⟹   XP_054960840
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22156,639,252 - 56,679,895 (-)NCBI
NHGRI_mPanPan12056,632,380 - 56,672,958 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034803136   ⟸   XM_034947245
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B7R0 (UniProtKB/TrEMBL),   A0A2R9BDE7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034803135   ⟸   XM_034947244
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B7R0 (UniProtKB/TrEMBL),   A0A2R9BDE7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034803139   ⟸   XM_034947248
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034803138   ⟸   XM_034947247
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B7R0 (UniProtKB/TrEMBL),   A0A2R9BDE7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000025101   ⟸   ENSPPAT00000047927
RefSeq Acc Id: ENSPPAP00000025107   ⟸   ENSPPAT00000047933
RefSeq Acc Id: ENSPPAP00000025114   ⟸   ENSPPAT00000047940
RefSeq Acc Id: XP_054960840   ⟸   XM_055104865
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B7R0 (UniProtKB/TrEMBL)
Protein Domains
C2H2-type   Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035684 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047927.1 UniProtKB/TrEMBL
  ENSPPAT00000047933.1 UniProtKB/TrEMBL
  ENSPPAT00000047940.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro ADNP/ADNP2 UniProtKB/TrEMBL
  ADNP_Znf UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene ADNP ENTREZGENE
PANTHER ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN UniProtKB/TrEMBL
  PTHR15740 UniProtKB/TrEMBL
Pfam ADNP_N UniProtKB/TrEMBL
  Homeodomain UniProtKB/TrEMBL
PROSITE HOMEOBOX_2 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A2R9B691_PANPA UniProtKB/TrEMBL
  A0A2R9B7R0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BDE7 ENTREZGENE, UniProtKB/TrEMBL