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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of binding
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Accession:GO:0051099 term browser browse the term
Definition:Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
Synonyms:exact_synonym: up regulation of binding;   upregulation of binding
 narrow_synonym: activation of binding;   stimulation of binding


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negative regulation of guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha IDA RGD PMID:9582312 RGD:1581075 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta IDA RGD PMID:9582312 RGD:1581075 NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA RGD PMID:9582312 RGD:1581075 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Gpsm1 G-protein signaling modulator 1 involved_in ISO (PMID:11024022) RGD PMID:11024022 NCBI chr 3:9,140,816...9,167,828
Ensembl chr 3:9,128,636...9,167,827 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Stmn1 stathmin 1 involved_in ISO (PMID:25198505) RGD PMID:25198505 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
negative regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ripor1 RHO family interacting cell polarization regulator 1 involved_in ISO (PMID:25588844) RGD PMID:25588844 NCBI chr19:33,477,750...33,506,424
Ensembl chr19:33,477,793...33,506,420 		JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23241886)
(PMID:25588844)		 UniProt
RGD		 PMID:23241886 PMID:25588844 GO_REF:0000024 NCBI chr17:40,323,748...40,547,482
Ensembl chr17:40,323,867...40,548,092 		JBrowse link
positive regulation of actin filament binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Poldip2 DNA polymerase delta interacting protein 2 IMP RGD PMID:30354218 RGD:124713558 NCBI chr10:63,407,237...63,417,605
Ensembl chr10:63,407,213...63,417,605 		JBrowse link
positive regulation of chromatin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kat2b lysine acetyltransferase 2B IMP Ep300 RGD PMID:20870727 RGD:9590266 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Kdm1a lysine demethylase 1A IMP RGD PMID:20418916 RGD:9588315 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IMP RGD PMID:25135974 RGD:9589119 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794 		JBrowse link
G Mfn2 mitofusin 2 IMP Tfap2a RGD PMID:27997345 RGD:12910740 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
positive regulation of collagen binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2 integrin subunit alpha 2 IMP epithelial cell binding mediated by syndecan-2 RGD PMID:19394307 RGD:2307393 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
positive regulation of DNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ep300 E1A binding protein p300 IMP RGD PMID:19057620 RGD:2311715 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Itga2 integrin subunit alpha 2 IMP DNA binding by NF-kappaB RGD PMID:19239475 RGD:2307394 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
G Jak2 Janus kinase 2 IMP Stat3 RGD PMID:15322111 RGD:1641932 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IMP RGD PMID:12873812 RGD:10059626 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IMP RGD PMID:11181516 RGD:2311195 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Tlr4 toll-like receptor 4 IMP RGD PMID:16272348 RGD:1598594 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of GTP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rapgef3 Rap guanine nucleotide exchange factor 3 IMP Ran-GTP RGD PMID:18689492 RGD:9835375 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521 		JBrowse link
positive regulation of guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tns3 tensin 3 involved_in ISO (PMID:27505886) RGD PMID:27505886 NCBI chr14:83,173,649...83,405,671
Ensembl chr14:83,173,649...83,405,998 		JBrowse link
positive regulation of microtubule binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:21229611 RGD:10403032 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
positive regulation of mRNA binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpl heterogeneous nuclear ribonucleoprotein L IMP RGD PMID:19273590 RGD:9999430 NCBI chr 1:84,098,558...84,111,568
Ensembl chr 1:84,100,879...84,111,553 		JBrowse link
positive regulation of protein binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 IMP Npc1l1, Rab11a, Myo5b RGD PMID:21844200 RGD:5688279 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Cald1 caldesmon 1 IDA RGD PMID:3384851 RGD:2303065 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 IMP Akt1-Hsp90 RGD PMID:18443201 RGD:4108490 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 IDA RGD PMID:11415446 RGD:4892111 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta IDA RGD PMID:7908909 RGD:633201 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690 		JBrowse link
G Pacs1 phosphofurin acidic cluster sorting protein 1 IMP RGD PMID:9695949 RGD:633354 NCBI chr 1:202,437,503...202,569,473
Ensembl chr 1:202,437,505...202,569,473 		JBrowse link
G Plk2 polo-like kinase 2 IDA Sipa1l1 binding to Btcr and Fbxw11 RGD PMID:18723513 RGD:7241135 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Ramp1 receptor activity modifying protein 1 IDA RGD PMID:11556887 RGD:1299115 NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151 		JBrowse link
G Ramp2 receptor activity modifying protein 2 IDA RGD PMID:11556887 RGD:1299115 NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Trim28 tripartite motif-containing 28 IDA RGD PMID:12748187 RGD:1299608 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380 		JBrowse link
positive regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epha4 Eph receptor A4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12775584)		 UniProt
RGD		 PMID:12775584 GO_REF:0000024 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Poldip2 DNA polymerase delta interacting protein 2 IDA RGD PMID:30726115 RGD:124713559 NCBI chr10:63,407,237...63,417,605
Ensembl chr10:63,407,213...63,417,605 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    biological regulation 13559
      regulation of molecular function 1784
        regulation of binding 59
          positive regulation of binding 34
            negative regulation of guanyl-nucleotide exchange factor activity + 8
            positive regulation of DNA binding + 6
            positive regulation of GTP binding + 4
            positive regulation of RNA binding + 1
            positive regulation of calcium ion binding 0
            positive regulation of chromatin binding + 4
            positive regulation of collagen binding 1
            positive regulation of ferrous iron binding 0
            positive regulation of heparan sulfate binding 0
            positive regulation of lipid binding 0
            positive regulation of protein binding + 12
paths to the root