RGN (regucalcin) - Rat Genome Database

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Gene: RGN (regucalcin) Pan paniscus
Analyze
Symbol: RGN
Name: regucalcin
RGD ID: 11929158
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); gluconolactonase activity (ortholog); zinc ion binding (ortholog); INVOLVED IN aging (ortholog); cellular calcium ion homeostasis (ortholog); kidney development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Chemical and Drug Induced Liver Injury (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: regucalcin (senescence marker protein-30)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X47,371,225 - 47,388,881 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX47,371,226 - 47,388,881 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X39,513,135 - 39,530,188 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
cellular calcium ion homeostasis  (ISO)
kidney development  (ISO)
L-ascorbic acid biosynthetic process  (ISO)
liver development  (ISO)
liver regeneration  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of bone development  (ISO)
negative regulation of calcium-dependent ATPase activity  (ISO)
negative regulation of cyclic-nucleotide phosphodiesterase activity  (ISO)
negative regulation of DNA biosynthetic process  (ISO)
negative regulation of DNA catabolic process  (ISO)
negative regulation of epithelial cell proliferation  (ISO)
negative regulation of flagellated sperm motility  (ISO)
negative regulation of GTPase activity  (ISO)
negative regulation of leucine-tRNA ligase activity  (ISO)
negative regulation of nitric oxide biosynthetic process  (ISO)
negative regulation of phosphoprotein phosphatase activity  (ISO)
negative regulation of protein kinase activity  (ISO)
negative regulation of protein phosphorylation  (ISO)
negative regulation of RNA biosynthetic process  (ISO)
positive regulation of ATP-dependent activity  (ISO)
positive regulation of ATPase-coupled calcium transmembrane transporter activity  (ISO)
positive regulation of dUTP diphosphatase activity  (ISO)
positive regulation of fatty acid biosynthetic process  (ISO)
positive regulation of glucose metabolic process  (ISO)
positive regulation of GTPase activity  (ISO)
positive regulation of phosphatase activity  (ISO)
positive regulation of proteolysis involved in cellular protein catabolic process  (ISO)
positive regulation of superoxide dismutase activity  (ISO)
positive regulation of triglyceride biosynthetic process  (ISO)
regulation of calcium-mediated signaling  (ISO)
spermatogenesis  (ISO)

Cellular Component
cytoplasm  (ISO)
cytosol  (ISO)
nucleus  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
RGN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X47,371,225 - 47,388,881 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX47,371,226 - 47,388,881 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X39,513,135 - 39,530,188 (+)NCBIMhudiblu_PPA_v0panPan3
RGN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX47,078,355 - 47,093,314 (+)EnsemblGRCh38hg38GRCh38
GRCh38X47,078,414 - 47,093,313 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X46,937,842 - 46,952,712 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X46,822,719 - 46,837,656 (+)NCBINCBI36hg18NCBI36
Build 34X46,696,510 - 46,708,966NCBI
CeleraX51,129,720 - 51,148,035 (+)NCBI
Cytogenetic MapXp11.3NCBI
HuRefX44,651,176 - 44,667,384 (+)NCBIHuRef
CHM1_1X46,969,564 - 46,984,507 (+)NCBICHM1_1
Rgn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X20,416,005 - 20,428,328 (+)NCBIGRCm39mm39
GRCm39 EnsemblX20,416,026 - 20,428,328 (+)Ensembl
GRCm38X20,549,766 - 20,562,089 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX20,549,787 - 20,562,089 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X20,126,944 - 20,139,213 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X19,706,777 - 19,719,046 (+)NCBImm8
CeleraX18,681,357 - 18,693,626 (+)NCBICelera
Cytogenetic MapXA1.3NCBI
Rgn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X1,619,030 - 1,634,456 (-)NCBImRatBN7.2
mRatBN7.2 EnsemblX1,619,032 - 1,634,450 (-)Ensembl
Rnor_6.0X1,833,484 - 1,848,904 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX1,833,492 - 1,848,904 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X2,626,525 - 2,641,949 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X13,037,171 - 13,052,846NCBIRGSC3.4rn4RGSC3.4
CeleraX2,182,952 - 2,198,371 (-)NCBICelera
Cytogenetic MapXq11NCBI
Rgn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955516955,680 - 978,910 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955516958,416 - 978,829 (-)NCBIChiLan1.0ChiLan1.0
RGN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X40,697,292 - 40,715,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX40,698,768 - 40,715,490 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX15,074,578 - 15,090,960 (+)NCBI
ROS_Cfam_1.0X40,818,343 - 40,849,916 (+)NCBI
UMICH_Zoey_3.1X40,806,174 - 40,837,694 (+)NCBI
UNSW_CanFamBas_1.0X40,793,810 - 40,825,378 (+)NCBI
UU_Cfam_GSD_1.0X40,886,864 - 40,918,439 (+)NCBI
Rgn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X33,032,122 - 33,050,817 (+)NCBI
SpeTri2.0NW_00493650212,872,938 - 12,891,270 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX41,726,526 - 41,749,726 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X41,725,660 - 41,749,736 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X46,902,494 - 46,926,414 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RGN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X44,282,825 - 44,299,027 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 EnsemblX44,285,601 - 44,299,258 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660769,539,184 - 9,555,388 (+)NCBIVero_WHO_p1.0
Rgn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248873,881,624 - 3,900,144 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000045912   ⟹   ENSPPAP00000023092
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX47,371,226 - 47,388,881 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045931   ⟹   ENSPPAP00000023111
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX47,374,529 - 47,388,515 (+)Ensembl
RefSeq Acc Id: XM_003809673   ⟹   XP_003809721
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1X47,371,225 - 47,388,881 (+)NCBI
Mhudiblu_PPA_v0X39,513,136 - 39,530,188 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003809674   ⟹   XP_003809722
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1X47,371,225 - 47,388,881 (+)NCBI
Mhudiblu_PPA_v0X39,513,135 - 39,530,187 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008961948   ⟹   XP_008960196
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1X47,371,228 - 47,388,881 (+)NCBI
Mhudiblu_PPA_v0X39,513,138 - 39,530,187 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008961949   ⟹   XP_008960197
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1X47,371,228 - 47,388,881 (+)NCBI
Mhudiblu_PPA_v0X39,513,138 - 39,530,187 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003809721 (Get FASTA)   NCBI Sequence Viewer  
  XP_003809722 (Get FASTA)   NCBI Sequence Viewer  
  XP_008960196 (Get FASTA)   NCBI Sequence Viewer  
  XP_008960197 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003809722   ⟸   XM_003809674
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003809721   ⟸   XM_003809673
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008960196   ⟸   XM_008961948
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008960197   ⟸   XM_008961949
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000023092   ⟸   ENSPPAT00000045912
RefSeq Acc Id: ENSPPAP00000023111   ⟸   ENSPPAT00000045931


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034719 Ensembl, ENTREZGENE
Ensembl Protein ENSPPAP00000023092 ENTREZGENE
NCBI Gene RGN ENTREZGENE